Page last updated: 2024-08-17

biguanides and olanexidine

biguanides has been researched along with olanexidine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's4 (25.00)29.6817
2010's4 (25.00)24.3611
2020's5 (31.25)2.80

Authors

AuthorsStudies
Kudo, S; Miyamoto, G; Morita, S; Odomi, M; Uchida, M; Umehara, K1
Kudo, S; Miyamoto, G; Mizooku, Y; Odomi, M; Sogawa, Y; Sugai, T1
Kajimura, K; Mimura, M; Nishimura, H; Sakagami, Y; Yokoyama, H1
Hirao, Y; Kudo, S; Miyamoto, G; Morita, S; Odomi, M; Uchida, M; Umehara, K1
Hirao, Y; Kudo, S; Miyamoto, G; Morita, S; Ohtani, T; Uchida, M; Umehara, K1
Kajimura, K; Nishimura, H; Sakagami, Y1
Koga, T; Miyamoto, G; Ohtani, T; Shimokawa, Y; Umehara, K1
Hagi, A; Inoue, Y; Iwata, K; Nakata, H; Nii, T; Tsubotani, Y1
Hagi, A; Imamura, T; Inoue, Y; Nakata, H; Nii, T; Tsubotani, Y1
Kar, SK; Roy, P; Shahi, MK1
Abe, Y; Fukuda, K; Harada, H; Hirukawa, K; Hori, S; Irino, T; Ishida, T; Isobe, Y; Kawakubo, H; Kitagawa, Y; Kitago, M; Kondo, T; Maeda, Y; Mayanagi, S; Nakamura, R; Obara, H; Okabayashi, K; Oshima, G; Sato, Y; Sekimoto, Y; Shinoda, M; Shito, M; Takeuchi, M; Tsuruta, M; Wada, N; Yagi, H; Yokose, T1
Hu, Y; Kumar, V; Liu, H; Lu, C; Rao, Z; Xiao, Y1
Vogt, D; Willy, C1
Hayashi, K; Kawakubo, H; Kitagawa, Y; Kondo, T; Maeda, Y; Obara, H; Okabayashi, K; Sato, Y; Sekimoto, Y; Shinoda, M; Takeuchi, M1
Atmar, RL; Estes, MK; Ettayebi, K; Hagi, A; Imai, K; Neill, FH; Prasad, BVV; Salmen, W1
Boermeester, MA; Buis, DR; Dreissen, YE; Goosen, JH; Griekspoor, M; Groenen, H; Harmsen, WJ; Ijpma, FF; Jalalzadeh, H; Schaad, RR; Segers, P; van der Laan, MJ; van der Zwet, WC; Wolfhagen, N1

Reviews

1 review(s) available for biguanides and olanexidine

ArticleYear
Efficacy of different preoperative skin antiseptics on the incidence of surgical site infections: a systematic review, GRADE assessment, and network meta-analysis.
    The Lancet. Microbe, 2022, Volume: 3, Issue:10

    Topics: Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Ethanol; GRADE Approach; Humans; Incidence; Iodine; Network Meta-Analysis; Povidone-Iodine; Surgical Wound Infection

2022

Trials

2 trial(s) available for biguanides and olanexidine

ArticleYear
Comparison of olanexidine versus povidone-iodine for preventing surgical site infection in gastrointestinal surgery: study protocol for a multicentre, single-blind, randomised controlled clinical trial.
    BMJ open, 2019, 05-28, Volume: 9, Issue:5

    Topics: Anti-Infective Agents, Local; Biguanides; Digestive System Surgical Procedures; Humans; Povidone-Iodine; Research Design; Surgical Wound Infection

2019
Aqueous olanexidine versus aqueous povidone-iodine for surgical skin antisepsis on the incidence of surgical site infections after clean-contaminated surgery: a multicentre, prospective, blinded-endpoint, randomised controlled trial.
    The Lancet. Infectious diseases, 2020, Volume: 20, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Antisepsis; Biguanides; Dermatologic Agents; Female; Humans; Incidence; Japan; Male; Middle Aged; Povidone-Iodine; Prospective Studies; Surgical Wound Infection; Treatment Outcome; Young Adult

2020

Other Studies

13 other study(ies) available for biguanides and olanexidine

ArticleYear
Metabolism of 1-(3,4-dichlorobenzyl)-5-octylbiguanide in the dog.
    Xenobiotica; the fate of foreign compounds in biological systems, 1998, Volume: 28, Issue:5

    Topics: Animals; Anti-Infective Agents, Local; Biguanides; Biotransformation; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dogs; Feces; Hydroxylation; Male; Molecular Structure; Radioisotope Dilution Technique; Spectrometry, Mass, Fast Atom Bombardment

1998
High-performance liquid chromatography-electrospray tandem mass spectrometry for the measurement of 1-(3,4-dichlorobenzyl)-5-octylbiguanide in human serum.
    Therapeutic drug monitoring, 1998, Volume: 20, Issue:6

    Topics: Adult; Anti-Infective Agents, Local; Biguanides; Chromatography, High Pressure Liquid; Drug Stability; Freezing; Humans; Male; Mass Spectrometry; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity

1998
Electron-microscopic study of the bactericidal effect of OPB-2045, a new mono-biguanide disinfectant produced from biguanide group compounds, against Pseudomonas aeruginosa.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:2

    Topics: Anti-Infective Agents, Local; Biguanides; Colony Count, Microbial; Disinfectants; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Microscopy, Electron; Pseudomonas aeruginosa

1999
Oxidative cleavage of the octyl side chain of 1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045) in rat and dog liver preparations.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:8

    Topics: Animals; Biguanides; Chlorobenzoates; Chromatography, High Pressure Liquid; Dogs; In Vitro Techniques; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Species Specificity

2000
In vitro characterization of the oxidative cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:12

    Topics: Animals; Anti-Infective Agents; Biguanides; Biotransformation; Chromatography, High Pressure Liquid; Dogs; Enzyme Inhibitors; In Vitro Techniques; Microsomes, Liver; Oxidation-Reduction

2000
Electron-microscopic study of the bactericidal effect of OPB-2045, a new disinfectant produced from biguanide group compounds, against methicillin-resistant Staphylococcus aureus.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:12

    Topics: Anti-Infective Agents, Local; Biguanides; Cell Division; Disinfectants; Dose-Response Relationship, Drug; Methicillin Resistance; Microbial Sensitivity Tests; Microscopy, Electron; Staphylococcus aureus

2000
Oxidative one-carbon cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:1

    Topics: Animals; Anti-Infective Agents; Biguanides; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Dogs; Enzyme Inhibitors; Microsomes, Liver; NADP; Oxidation-Reduction; Quinidine; Quinine; Spectrometry, Mass, Electrospray Ionization

2004
Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Cell Membrane; Chlorhexidine; Escherichia coli; Gluconates; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Povidone-Iodine

2015
Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys.
    Journal of medical microbiology, 2017, Volume: 66, Issue:5

    Topics: Acinetobacter baumannii; Administration, Topical; Animals; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Gluconates; Glucuronates; Macaca fascicularis; Povidone-Iodine; Preoperative Care; Skin; Staphylococcus aureus; Staphylococcus epidermidis; Surgical Wound Infection

2017
Understanding the anxiety phenomenology in psychotic prodrome: A case report.
    Asian journal of psychiatry, 2017, Volume: 28

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Biguanides; Clonazepam; Drug Therapy, Combination; Female; Humans; Middle Aged; Prodromal Symptoms; Psychotic Disorders; Treatment Outcome

2017
Carbon-carbon Bond Cleavage Catalyzed by Human Cytochrome P450 Enzymes: α-ketol as the Key Intermediate Metabolite in Sequential Metabolism of Olanexidine.
    Drug metabolism letters, 2021, Volume: 14, Issue:1

    Topics: Biguanides; Carbon; Catalysis; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Microsomes, Liver

2021
Should olanexidine be used routinely for surgical skin antisepsis?
    The Lancet. Infectious diseases, 2020, Volume: 20, Issue:11

    Topics: Antisepsis; Biguanides; Humans; Incidence; Povidone-Iodine; Prospective Studies; Surgical Wound Infection

2020
Antiviral Activity of Olanexidine-Containing Hand Rub against Human Noroviruses.
    mBio, 2022, 04-26, Volume: 13, Issue:2

    Topics: Animals; Antiviral Agents; Biguanides; Blood Group Antigens; Disinfectants; Gastroenteritis; Humans; Norovirus; Swine

2022