Page last updated: 2024-09-02

bifendate and chalcone

bifendate has been researched along with chalcone in 2 studies

Compound Research Comparison

Studies (bifendate)	Trials (bifendate)	Recent Studies (post-2010) (bifendate)	Studies (chalcone)	Trials (chalcone)	Recent Studies (post-2010) (chalcone)
124	8	43	2,015	22	1,086

Protein Interaction Comparison

Protein	Taxonomy	chalcone (IC50)
perilipin-5	Homo sapiens (human)	4.245
perilipin-1	Homo sapiens (human)	4.194
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	Homo sapiens (human)	4.2195
Amine oxidase [flavin-containing] A	Homo sapiens (human)	1.41
Amine oxidase [flavin-containing] B	Homo sapiens (human)	1.41
Sortase A	Streptococcus mutans	5

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gu, X; Lai, Y; Ma, Y; Peng, H; Peng, S; Ren, Z; Tang, X; Zhang, Y	1
Gu, X; Peng, H; Peng, S; Ren, Z; Zhang, Y	1

Other Studies

2 other study(ies) available for bifendate and chalcone

Article	Year
Synthesis and biological evaluation of bifendate-chalcone hybrids as a new class of potential P-glycoprotein inhibitors. Bioorganic & medicinal chemistry, 2012, Apr-15, Volume: 20, Issue:8 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; K562 Cells; Structure-Activity Relationship	2012
Bifendate-chalcone hybrids: a new class of potential dual inhibitors of P-glycoprotein and breast cancer resistance protein. Biochemical and biophysical research communications, 2014, Dec-12, Volume: 455, Issue:3-4 Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biphenyl Compounds; Chalcone; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Inhibitory Concentration 50; Neoplasm Proteins	2014

Article

Year

Synthesis and biological evaluation of bifendate-chalcone hybrids as a new class of potential P-glycoprotein inhibitors.

Bioorganic & medicinal chemistry, 2012, Apr-15, Volume: 20, Issue:8

Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; K562 Cells; Structure-Activity Relationship

2012

Bifendate-chalcone hybrids: a new class of potential dual inhibitors of P-glycoprotein and breast cancer resistance protein.

Biochemical and biophysical research communications, 2014, Dec-12, Volume: 455, Issue:3-4

Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biphenyl Compounds; Chalcone; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Inhibitory Concentration 50; Neoplasm Proteins

2014