Page last updated: 2024-08-21

bicuculline and valproic acid

bicuculline has been researched along with valproic acid in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (60.38)	18.7374
1990's	14 (26.42)	18.2507
2000's	4 (7.55)	29.6817
2010's	3 (5.66)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bruinvels, J; de Boer, T; Metselaar, HJ	1
Hayashi, T; Negishi, K	1
Stone, WE	1
Bulaev, VM; Ostrovskaia, RU	1
Rose, D	1
Ciesielski, L; Kempf, E; Mack, G; Maitre, M; Mandel, P; Simler, S	1
Frey, HH; Löscher, W	1
Molodavkin, GM; Ostrovskaia, RU	1
Markovich, VV; Molodavkin, GM; Ostrovskaia, RU	1
Fujita, S; Kusunoki, M; Sakanoue, Y; Shoji, Y; Utsunomiya, J; Yamamura, T; Yanagi, H	1
Dai, X; Li, Y; Yang, S	1
Dickinson, SL; Jackson, HC; Nutt, DJ; Ripley, TL	1
Bhowmick, S; Bose, R; Pal, M; Pal, SP	1
Hamilton, MS; Shephard, RA	1
Aley, KO; Kulkarni, SK	1
Amenta, F; Erdö, SL; Ezer, E; Matuz, J; Wolff, JR	1
Bhargava, KP; Gupta, GP; Gupta, MB	1
Akhundov, RA; Rozhanets, VV; Val'dman, AV; Voronina, TA	1
Kent, AP; Webster, RA	1
Durán, JA; Miñano, FJ; Sancibrián, M; Serrano, JS	1
Lloyd, KG	1
Klee, MR; Preisendörfer, U; Zeise, ML	1
Piredda, SG; Swinyard, EA; Woodhead, JH	1
Hinko, CN; Lee, JA; Moore, JA; Nicholson, JM; Scott, KR; Zalucky, TB	1
Chweh, AY; Coleman, JC; Shenoy, AK; Swinyard, EA	1
Bulayev, VM; Ostrovskaya, RU; Zakusov, VV	1
Bruinvels, J; van der Laan, JW	1
Bichard, AR; Little, HJ	1
Harrison, NL; Simmonds, MA	1
Engel, JA; Liljequist, S	1
DeFeudis, FV; Jadot, G; Mandel, P; Mesdjian, E; Valli, M	1
Bizière, K; Calassi, R; Chambon, JP; Leyris, R; Maruani, J; Molimard, JC; Rodier, D; Roncucci, R; Sigault, G	1
Kharlamov, AN; Raevskiĭ, KS	1
Kuruvilla, A; Uretsky, N	1
Ostrovskaia, RU; Zakusov, VV	1
Depaulis, A; Rodgers, RJ	1
Alkadhi, KA; Tian, LM	1
Gean, PW; Huang, CC; Hung, CR; Tsai, JJ	1
Cao, BJ; Peng, NA	1
DeBold, JF; Frye, CA; Mermelstein, PG	1
Amico-Roxas, M; Caruso, A; Cutuli, VM; de Bernardis, E; Lucenti, A; Villari, L	1
Ayata, G; Cutrer, FM; Limmroth, V; Moskowitz, MA	1
Dalvi, A; Rodgers, RJ	1
Chunngam, T; Patarapanich, C; Sooksawate, T; Tantisira, B; Tantisira, MH	1
Albus, H; Williamson, R	1
Alkadhi, KA; Otoom, SA	1
Chen, Z; Fujii, Y; Ishizawa, K; Kamei, C; Okuma, C; Sugimoto, Y	1
Aoyagi, Y; Ohta, A; Watanabe, Y; Yamada, K	1
Aubry, JM; Moscianese, K; Navarra, P; Pozzoli, G; Preziosi, P; Tringali, G; Vairano, M; Zamori, C	1
Jiruska, P; Mares, P; Otáhal, J; Proks, J	1
Brismar, T; Englund, M; Hyllienmark, L	1
Abe, M; Egashira, N; Fujiwara, M; Iwasaki, K; Mishima, K; Niki, T; Oishi, R; Shirakawa, A	1
Fueta, Y; Kanda, Y; Sekino, Y; Ueno, S; Yoshida, S	1

Reviews

1 review(s) available for bicuculline and valproic acid

Article	Year
[GABAergic theory of epilepsy]. La Revue du praticien, 1986, Jan-21, Volume: 36, Issue:5 Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Brain; Dogs; Epilepsy; gamma-Aminobutyric Acid; Humans; Mice; Nerve Endings; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Receptors, GABA-A; Synapses; Valproic Acid	1986

Trials

1 trial(s) available for bicuculline and valproic acid

Article	Year
gamma-Aminobutyric acid enhances the tone of human internal anal sphincter. The Journal of surgical research, 1991, Volume: 51, Issue:4 Topics: Anal Canal; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Humans; Muscimol; Muscle Contraction; Muscle Relaxation; Pressure; Receptors, GABA-A; Valproic Acid	1991

Other Studies

51 other study(ies) available for bicuculline and valproic acid

Article	Year
Suppression of GABA-induced abstinence behaviour in naive rats by morphine and bicuculline. Life sciences, 1977, Mar-15, Volume: 20, Issue:6 Topics: Aminobutyrates; Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoquinolines; Male; Morphine; Motor Activity; Naloxone; Rats; Receptors, Drug; Receptors, Opioid; Substance Withdrawal Syndrome; Valerates; Valproic Acid	1977
Suppression of retinal spike discharge by dipropylacetate (Depakene): a possible involvement of GABA. Brain research, 1979, Oct-19, Volume: 175, Issue:2 Topics: Animals; Bicuculline; Carps; Evoked Potentials; gamma-Aminobutyric Acid; Neural Inhibition; Photic Stimulation; Retina; Synaptic Transmission; Valproic Acid	1979
Effects of alterations in the metabolism of gamma-aminobutyrate on convulsant potencies. Epilepsia, 1977, Volume: 18, Issue:4 Topics: 3-Mercaptopropionic Acid; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Diacetyl; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Hydrazines; Male; Mice; Pentylenetetrazole; Phenelzine; Picrotoxin; Pyridoxine; Reaction Time; Seizures; Thiones; Valproic Acid	1977
[Effect of GABA-ergic substances on the analgesic effect of morphine in rats]. Biulleten' eksperimental'noi biologii i meditsiny, 1979, Volume: 88, Issue:7 Topics: Analgesia; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Male; Morphine; Rats; Receptors, Drug; Thiosemicarbazones; Time Factors; Valproic Acid; Vocalization, Animal	1979
Facilitation of bicuculline- and picrotoxin-induced seizures by sodium valproate in rats. Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 239, Issue:1 Topics: Animals; Bicuculline; Drug Synergism; Male; Picrotoxin; Rats; Seizures; Valproic Acid	1979
Involvement of central GABA-ergic systems in convulsions and aggressive behavior. Advances in experimental medicine and biology, 1979, Volume: 123 Topics: 4-Aminobutyrate Transaminase; Aggression; Allylglycine; Animals; Bicuculline; Brain; Fatty Acids; gamma-Aminobutyric Acid; Humans; Kinetics; Mice; Muscimol; Picrotoxin; Rats; Seizures; Structure-Activity Relationship; Valproic Acid	1979
Di-n-propylacetic acid--profile of anticonvulsant activity in mice. Arzneimittel-Forschung, 1976, Volume: 26, Issue:2 Topics: Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electroshock; Ethosuximide; Female; Male; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Seizures; Strychnine; Trimethadione; Valerates; Valproic Acid	1976
[GABA-ergic mechanism of action of diazepam on cerebral cortex neurons]. Biulleten' eksperimental'noi biologii i meditsiny, 1976, Volume: 82, Issue:9 Topics: Aminobutyrates; Animals; Bicuculline; Brain Chemistry; Diazepam; Evoked Potentials; GABA Antagonists; Male; Neurons; Rats; Semicarbazides; Somatosensory Cortex; Valproic Acid	1976
[The effect of substnaces altering gamma-aminobutyric acid metabolism on the recovery cycle of the interzonal response of the cat motor cortex]. Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 79, Issue:2 Topics: Aminobutyrates; Animals; Arecoline; Bemegride; Benactyzine; Bicuculline; Caffeine; Cats; Drug Interactions; Electrophysiology; gamma-Aminobutyric Acid; Motor Cortex; Receptors, Drug; Semicarbazides; Somatosensory Cortex; Sulfhydryl Compounds; Valproic Acid	1975
[Effect of sodium valproate on bicuculline-induced epileptiform activity in rat hippocampal slices in vitro]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1991, Volume: 22, Issue:1 Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Rats; Rats, Inbred Strains; Valproic Acid	1991
Anticonvulsant activity of the imidazoline 6,7-benzoidazoxan. Epilepsy research, 1991, Volume: 9, Issue:2 Topics: Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Dioxanes; Electroshock; Imidazoles; Male; Mice; Phenytoin; Postural Balance; Rats; Rats, Inbred Strains; Seizures; Valproic Acid	1991
Antiulcer activity of N-phthaloyl GABA--a new GABA mimetic agent. Indian journal of experimental biology, 1990, Volume: 28, Issue:2 Topics: 3-Mercaptopropionic Acid; Animals; Anti-Ulcer Agents; Bicuculline; Cimetidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Rats; Stomach Ulcer; Valproic Acid	1990
Chlordiazepoxide and valproate enhancement of saline drinking by nondeprived rats: effects of bicuculline, picrotoxin and Ro15-1788. Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:2 Topics: Animals; Bicuculline; Chlordiazepoxide; Dose-Response Relationship, Drug; Drinking Behavior; Drug Combinations; Drug Interactions; Flumazenil; Male; Picrotoxin; Rats; Rats, Inbred Strains; Sodium Chloride; Valproic Acid	1989
GABAergic agents-induced antinociceptive effect in mice. Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:10 Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Mice; Morphine; Muscimol; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds; Valproic Acid	1989
GABAA receptors in the rat stomach may mediate mucoprotective effects. European journal of pharmacology, 1989, Jun-08, Volume: 165, Issue:1 Topics: Administration, Oral; Aminooxyacetic Acid; Animals; Anti-Ulcer Agents; Baclofen; Bicuculline; Binding, Competitive; Ethanol; gamma-Aminobutyric Acid; Gastric Mucosa; Ligands; Muscimol; Rats; Receptors, GABA-A; Stomach Ulcer; Vagotomy; Valproic Acid	1989
Central GABA-ergic mechanism in stress-induced gastric ulceration. British journal of pharmacology, 1985, Volume: 84, Issue:3 Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cold Temperature; Epinephrine; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Hydrogen-Ion Concentration; Injections, Intraventricular; Male; Neurotransmitter Agents; Picrotoxin; Pylorus; Rats; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Valproic Acid	1985
[Mechanism of the tranquilizing action of electron structural analogs of nicotinamide]. Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:3 Topics: Animals; Benzodiazepinones; Bicuculline; Brain; Conflict, Psychological; Flumazenil; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Inosine; Male; Niacinamide; Radioligand Assay; Rats; Receptors, GABA-A; Serotonin; Synaptosomes; Tranquilizing Agents; Valproic Acid	1986
The role of GABA and excitatory amino acids in the development of the leptazol-induced epileptogenic EEG. Neuropharmacology, 1986, Volume: 25, Issue:9 Topics: Allylglycine; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Clonazepam; Dose-Response Relationship, Drug; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Time Factors; Valproic Acid	1986
Involvement of bicuculline-insensitive receptors in the hypothermic effect of GABA and its agonists. General pharmacology, 1985, Volume: 16, Issue:5 Topics: Amino Acids; Amino Acids, Neutral; Animals; Bicuculline; Body Temperature; Drug Interactions; Female; gamma-Aminobutyric Acid; Hypothermia; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors; Valproic Acid	1985
Valproate enhances inhibitory postsynaptic potentials in hippocampal neurons in vitro. Brain research, 1987, Dec-01, Volume: 435, Issue:1-2 Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neurons; Picrotoxin; Synapses; Valproic Acid	1987
Effect of stimulus intensity on the profile of anticonvulsant activity of phenytoin, ethosuximide and valproate. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3 Topics: Animals; Anticonvulsants; Bicuculline; Electroshock; Ethosuximide; Male; Mice; Pentylenetetrazole; Phenytoin; Picrotoxin; Seizures; Valproic Acid	1985
Spiro[4.5] and spiro[4.6] carboxylic acids: cyclic analogues of valproic acid. Synthesis and anticonvulsant evaluation. Journal of medicinal chemistry, 1985, Volume: 28, Issue:4 Topics: Animals; Anticonvulsants; Bicuculline; Carboxylic Acids; Male; Mice; Pentylenetetrazole; Picrotoxin; Spiro Compounds; Structure-Activity Relationship; Valproic Acid	1985
An analysis of the in vivo interactions between chemical convulsants and anticonvulsants. Life sciences, 1985, Aug-26, Volume: 37, Issue:8 Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Valproic Acid	1985
GABA-opiates interactions in the activity of analgesics. Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 265, Issue:1 Topics: Aminooxyacetic Acid; Analgesics, Opioid; Animals; Bicuculline; Cyclic GMP; Drug Interactions; gamma-Aminobutyric Acid; Male; Morphine; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Opioid; Structure-Activity Relationship; Valproic Acid	1983
Dipropylacetate-induced quasi-morphine abstinence behaviour in the rat: involvement of amygdaloid and thalamic structures. Brain research, 1981, Dec-14, Volume: 229, Issue:1 Topics: Amygdala; Animals; Bicuculline; Caudate Nucleus; Hippocampus; Humans; Male; Morphine; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Opioid; Substance Withdrawal Syndrome; Substantia Nigra; Thalamic Nuclei; Valproic Acid	1981
Drugs that increase gamma-aminobutyric acid transmission protect against the high pressure neurological syndrome. British journal of pharmacology, 1982, Volume: 76, Issue:3 Topics: Anesthetics; Animals; Bicuculline; Body Temperature; Flurazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Pressure; Seizures; Synaptic Transmission; Tremor; Valproic Acid	1982
Sodium valproate enhances responses to GABA receptor activation only at high concentrations. Brain research, 1982, Oct-28, Volume: 250, Issue:1 Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Medulla Oblongata; Muscimol; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Tissue Distribution; Valproic Acid	1982
Reversal of the anti-conflict action of valproate by various GABA and benzodiazepine antagonists. Life sciences, 1984, Jun-18, Volume: 34, Issue:25 Topics: Animals; Benzodiazepines; Benzodiazepinones; Bicuculline; Conflict, Psychological; Flumazenil; GABA Antagonists; Male; Motor Activity; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Valproic Acid	1984
Antinociceptive action of sodium valproate in the mouse. General pharmacology, 1983, Volume: 14, Issue:6 Topics: Acetates; Analgesics; Animals; Bicuculline; Male; Mice; Naloxone; Reaction Time; Valproic Acid	1983
Anticonvulsant activity of 4,9-dioxo-5,10-diazatetradecane (CM 40142), a new GABA derivative, in mice and photosensitive baboons). Arzneimittel-Forschung, 1984, Volume: 34, Issue:9 Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Electroshock; Female; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Papio; Pentylenetetrazole; Photic Stimulation; Seizures; Strychnine; Valproic Acid	1984
[Tranquilizing effect of n-dipropylacetate and other GABA-ergic substances in conflict situations]. Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:7 Topics: Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Caffeine; Conflict, Psychological; Male; Models, Psychological; Pantothenic Acid; Pentylenetetrazole; Piracetam; Pyrrolidinones; Rats; Tranquilizing Agents; Valproic Acid	1980
The interaction of chlordiazepoxide and sodium valproate in the nucleus accumbens of the rat. Life sciences, 1981, Jan-26, Volume: 28, Issue:4 Topics: Animals; Bicuculline; Chlordiazepoxide; Dopamine; Drug Synergism; Motor Activity; Nucleus Accumbens; Rats; Septal Nuclei; Valproic Acid	1981
[New evidence for a GABA-ergic component in the mechanism of action of benzodiazepine tranquilizers]. Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 91, Issue:5 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Bicuculline; Central Nervous System; Drug Interactions; gamma-Aminobutyric Acid; Male; Rabbits; Semicarbazides; Valproic Acid	1981
GABAergic influences on defensive fighting in rats. Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:3 Topics: Aggression; Aminocaproates; Animals; Baclofen; Bicuculline; Electroshock; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Valproic Acid; Vigabatrin	1982
Valproic acid inhibits the depolarizing rectification in neurons of rat amygdala. Neuropharmacology, 1994, Volume: 33, Issue:10 Topics: Amygdala; Animals; Bicuculline; Male; Membrane Potentials; Neurons; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin; Valproic Acid	1994
Valproic acid suppresses the synaptic response mediated by the NMDA receptors in rat amygdalar slices. Brain research bulletin, 1994, Volume: 33, Issue:3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Bicuculline; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Valproic Acid	1994
Magnesium valproate attenuates hyperactivity induced by dexamphetamine-chlordiazepoxide mixture in rodents. European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3 Topics: Analysis of Variance; Animals; Antipsychotic Agents; Bicuculline; Chlordiazepoxide; Dextroamphetamine; Drug Interactions; Female; GABA-A Receptor Antagonists; Isoniazid; Mice; Motor Activity; Picrotoxin; Rats; Rats, Sprague-Dawley; Valproic Acid	1993
Bicuculline infused into the hamster ventral tegmentum inhibits, while sodium valproate facilitates, sexual receptivity. Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:1 Topics: Animals; Bicuculline; Cricetinae; Estradiol; Female; GABA-A Receptor Antagonists; Mesocricetus; Ovariectomy; Posture; Progesterone; Receptors, GABA-B; Sexual Behavior, Animal; Tegmentum Mesencephali; Valproic Acid	1993
Effects of GABAergic drugs on ethanol-induced gastric lesions. Journal of physiology, Paris, 1993, Volume: 87, Issue:6 Topics: Animals; Baclofen; Bicuculline; Diazepam; Ethanol; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Hemorrhage; Indomethacin; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA; Valproic Acid	1993
Attenuation by valproate of c-fos immunoreactivity in trigeminal nucleus caudalis induced by intracisternal capsaicin. British journal of pharmacology, 1995, Volume: 116, Issue:8 Topics: Animals; Baclofen; Bicuculline; Brain Stem; Capsaicin; GABA Agents; GABA Antagonists; Guinea Pigs; Injections, Intraventricular; Male; Proto-Oncogene Proteins c-fos; Trigeminal Nuclei; Valproic Acid	1995
GABAergic influences on plus-maze behaviour in mice. Psychopharmacology, 1996, Volume: 128, Issue:4 Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; Diazepam; GABA Modulators; Male; Mice; Mice, Inbred DBA; Muscimol; Nipecotic Acids; Oximes; Picrotoxin; Valproic Acid	1996
Preliminary evaluation of the anticonvulsant activity of a valproic acid analog: N-(2-propylpentanoyl) urea. Research communications in molecular pathology and pharmacology, 1997, Volume: 97, Issue:2 Topics: Animals; Anticonvulsants; Bicuculline; Central Nervous System; Convulsants; Dose-Response Relationship, Drug; Electroshock; Lethal Dose 50; Male; Mice; Motor Activity; Pentylenetetrazole; Seizures; Sleep; Strychnine; Time Factors; Urea; Valproic Acid	1997
Electrophysiologic analysis of the actions of valproate on pyramidal neurons in the rat hippocampal slice. Epilepsia, 1998, Volume: 39, Issue:2 Topics: Action Potentials; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Hippocampus; Neural Conduction; Phenytoin; Potassium; Pyramidal Cells; Rats; Rats, Wistar; Refractory Period, Electrophysiological; Sodium Channels; Temperature; Valproic Acid	1998
Valproic acid intensifies epileptiform activity in the hippocampal pyramidal neurons. Neuroscience research, 1999, Dec-30, Volume: 35, Issue:4 Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Epilepsy; GABA Antagonists; Hippocampus; Male; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Channels; Valproic Acid	1999
Participation of GABAergic and histaminergic systems in inhibiting amygdaloid kindled seizures. Japanese journal of pharmacology, 2000, Volume: 82, Issue:1 Topics: Amygdala; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Histamine; Imidazoles; Kindling, Neurologic; Male; Muscimol; Rats; Rats, Wistar; Seizures; Thiourea; Valproic Acid	2000
Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain. Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:9 Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Convulsants; Diazepam; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Injections, Intraventricular; Male; Mice; Pentobarbital; Picrotoxin; Pyrazines; Seizures; Sleep; Time Factors; Valproic Acid	2001
Valproic acid inhibits corticotropin-releasing factor synthesis and release from the rat hypothalamus in vitro: evidence for the involvement of GABAergic neurotransmission. Journal of psychiatry & neuroscience : JPN, 2004, Volume: 29, Issue:6 Topics: Animals; Anticonvulsants; Bicuculline; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Gene Expression; Hippocampus; Male; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; RNA, Messenger; Secretory Rate; Synaptic Transmission; Tissue Culture Techniques; Valproic Acid	2004
Motor correlates of models of secondary bilateral synchrony and multiple epileptic foci. Seizure, 2007, Volume: 16, Issue:7 Topics: Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Convulsants; Data Interpretation, Statistical; Electrodes, Implanted; Electroencephalography; Electrophysiology; Epilepsy; Functional Laterality; Male; Movement; Posture; Rats; Rats, Wistar; Valproic Acid	2007
Effect of valproate, lamotrigine and levetiracetam on excitability and firing properties of CA1 neurons in rat brain slices. Cellular and molecular neurobiology, 2011, Volume: 31, Issue:4 Topics: Action Potentials; Animals; Bicuculline; CA1 Region, Hippocampal; Female; In Vitro Techniques; Lamotrigine; Levetiracetam; Male; Neurons; Piracetam; Rats; Rats, Sprague-Dawley; Triazines; Valproic Acid	2011
Effects of mood stabilizers on marble-burying behavior in mice: involvement of GABAergic system. Psychopharmacology, 2013, Volume: 226, Issue:2 Topics: Animals; Antipsychotic Agents; Baclofen; Behavior, Animal; Bicuculline; Carbamazepine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Lamotrigine; Lithium Carbonate; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Obsessive-Compulsive Disorder; Receptors, GABA-A; Triazines; Valproic Acid	2013
Prenatal exposure to valproic acid alters the development of excitability in the postnatal rat hippocampus. Neurotoxicology, 2018, Volume: 65 Topics: Action Potentials; Aging; Animals; Bicuculline; CA1 Region, Hippocampal; Excitatory Postsynaptic Potentials; Eye; Female; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Valproic Acid	2018