bicuculline and sr 95531

Topics: Animals; Bicuculline; Binding Sites; Brain; gamma-Aminobutyric Acid; Muscimol; Pyridazines; Rats; Receptors, GABA-A; Surface-Active Agents; Up-Regulation

Topics: Animals; Binding, Competitive; Convulsants; Female; GABA-A Receptor Antagonists; In Vitro Techniques; Mice; Models, Molecular; Molecular Conformation; Muscimol; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship

Topics: Alkaloids; Androstanes; Azasteroids; Azepines; Bicuculline; Crystallization; Dibenzazepines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Heterocyclic Compounds, 4 or More Rings; Heterocyclic Compounds, Bridged-Ring; Isoxazoles; Lactones; Models, Molecular; Molecular Conformation; Molecular Structure; Piperidines; Pyridazines; Receptors, GABA-A; Structure-Activity Relationship; Tubocurarine; X-Ray Diffraction

Topics: Animals; Bicuculline; Brain; Cerebellum; Frontal Lobe; GABA Antagonists; In Vitro Techniques; Kinetics; Male; Pyridazines; Radioligand Assay; Rats; Rats, Inbred Strains

Topics: Analgesics; Anesthesia; Animals; Bicuculline; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Medulla Oblongata; Microinjections; Nociceptors; Pyridazines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter

Topics: alpha-MSH; Animals; Bicuculline; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Pyridazines; Rats; Receptors, GABA-A

Topics: Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; GABA Antagonists; In Vitro Techniques; Isonicotinic Acids; Membrane Potentials; Pyridazines; Receptors, Nicotinic; Solutions; Swine

Topics: Animals; Bicuculline; Cerebral Cortex; Chlorides; Chlorine; GABA Antagonists; In Vitro Techniques; Male; Pyridazines; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes

Topics: Animals; Bicuculline; Chlorides; Electrophysiology; Ion Channels; Pyridazines; Rats; Receptors, GABA-A; Synapses

Topics: Animals; Bicuculline; Electric Stimulation; GABA Antagonists; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Peristalsis; Picrotoxin; Pyridazines; Receptors, GABA-A; Sesterterpenes

Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Median Eminence; Nipecotic Acids; Picrotoxin; Potassium; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes

Topics: Animals; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Embryo, Mammalian; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Kidney; Pyridazines; Rats; Receptors, GABA-A; Recombination, Genetic

Topics: Animals; Bicuculline; Binding Sites; Cells, Cultured; Chickens; Chloride Channels; Dose-Response Relationship, Drug; Flunitrazepam; GABA Antagonists; GABA-A Receptor Antagonists; Hexachlorocyclohexane; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Retina; Sesterterpenes; Signal Transduction

Topics: Anesthesia; Animals; Bicuculline; Depression, Chemical; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Male; Pepsinogens; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Vagotomy

Topics: Animals; Behavior, Animal; Bicuculline; Diazepam; GABA Antagonists; Glutamates; Glutamic Acid; Injections, Spinal; Isonicotinic Acids; Male; Medulla Oblongata; Microinjections; Nociceptors; Pyridazines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, GABA; Skin Temperature; Spinal Cord

Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela

Topics: Animals; Autoradiography; Bicuculline; Brain; Bridged Bicyclo Compounds, Heterocyclic; GABA Antagonists; Male; Membranes; Pyridazines; Rats; Rats, Wistar; Receptors, GABA; Sulfur Radioisotopes

Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Bicuculline; Binding Sites; Cells, Cultured; Chloride Channels; Chlorides; Etomidate; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Models, Molecular; Neurons; Pentobarbital; Pyridazines; Rats; Receptors, GABA-A

Topics: Animals; Baclofen; Bicuculline; Brain Stem; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Conduction System; In Vitro Techniques; Medulla Oblongata; Neurons; Organophosphorus Compounds; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Synapses

Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Bicuculline; Binding Sites; Binding, Competitive; Cell Line; Coturnix; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Transport; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Pentobarbital; Point Mutation; Pregnanediones; Pregnanolone; Protein Binding; Pyridazines; Receptors, GABA-A; Structure-Activity Relationship

Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Bicuculline; Brain Stem; Denervation; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Image Processing, Computer-Assisted; In Vitro Techniques; Isonicotinic Acids; Male; Neurons, Afferent; Nodose Ganglion; Presynaptic Terminals; Pyridazines; Rats; Rats, Inbred WKY; Receptors, GABA-A; Vagus Nerve

Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Flunarizine; GABA Antagonists; Hippocampus; Levetiracetam; Male; Piracetam; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures

Topics: Action Potentials; Animals; Bicuculline; Calcium; Convulsants; Electrophysiology; Enzyme Inhibitors; GABA Antagonists; Hippocampus; Male; Organ Culture Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Thapsigargin

Topics: Aging; Animals; Animals, Newborn; Bicuculline; Electrophysiology; Female; Ferrets; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Membrane Potentials; Periodicity; Picrotoxin; Pregnancy; Pyridazines; Retinal Ganglion Cells; Strychnine

Topics: Anesthetics; Animals; Anti-Anxiety Agents; Bicuculline; Carbolines; Cerebral Cortex; Chemoreceptor Cells; Clonazepam; Desoxycorticosterone; Diazepam; Feeding Behavior; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Glutathione; Hydra; Neurotransmitter Agents; Pregnanolone; Progesterone; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Tritium

Topics: Alkaline Phosphatase; Animals; Bicuculline; Caffeine; Calcineurin; Calcium; Calcium Channels; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Membrane Potentials; Phosphodiesterase Inhibitors; Phosphoric Monoester Hydrolases; Pyridazines; Receptors, Cytoplasmic and Nuclear; Receptors, GABA-A; Retinal Ganglion Cells; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin; Turtles

Topics: Animals; Bicuculline; Coloring Agents; GABA Antagonists; Ionophores; Kinetics; Male; Protein Binding; Pyridazines; Rats; Rats, Wistar; Receptors, GABA; Temperature; Thermodynamics; Thiocyanates

Topics: Animals; Bicuculline; Cells, Cultured; Coculture Techniques; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Histamine; Imidazoles; Models, Neurological; Neuroglia; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Cone Photoreceptor Cells; Swine

Topics: Action Potentials; Animals; Baclofen; Bicuculline; Dopamine; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Kinetics; Male; Neurons; Phosphinic Acids; Picrotoxin; Propanolamines; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Substantia Nigra

Topics: Animals; Auditory Cortex; Auditory Pathways; Bicuculline; Binding, Competitive; Brain Mapping; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gerbillinae; Male; Pyridazines; Synapses

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Evoked Potentials; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Strychnine; Sucrose; Tetrodotoxin

Topics: Amygdala; Animals; Anti-Anxiety Agents; Bicuculline; Evoked Potentials; Flurazepam; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Neurons; Nipecotic Acids; Nitrazepam; Oximes; Pyridazines; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Strychnine; Synaptic Transmission

Topics: Alcoholism; Animals; Azides; Benzodiazepines; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebellum; Drug Combinations; Female; Furosemide; GABA Agonists; GABA Antagonists; Ligands; Male; Pyridazines; Rats; Receptors, GABA-A; Sodium Chloride

Topics: Animals; Bicuculline; Electric Stimulation; Epilepsy; Evoked Potentials; Functional Laterality; GABA Antagonists; Hippocampus; Male; Pyridazines; Rats; Rats, Sprague-Dawley

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Evoked Potentials; Image Processing, Computer-Assisted; Immunohistochemistry; In Vitro Techniques; Male; Microscopy, Video; Patch-Clamp Techniques; Posterior Horn Cells; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Strychnine; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin

Topics: Animals; Bicuculline; Calcium; Cells, Cultured; Convulsants; Electrophysiology; Enzyme Inhibitors; Epilepsy; GABA Antagonists; Hippocampus; Immunohistochemistry; Microelectrodes; Nerve Net; Neurons; Pyridazines; Rats; Rats, Wistar; Thapsigargin

Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Bicuculline; GABA Antagonists; GABA-A Receptor Antagonists; Male; Nociceptors; Pain Measurement; Pregnanediones; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Reference Values; Spinal Cord; Steroids; Time Factors

Topics: Acrylates; Animals; Bicuculline; Calcium; Cholecystokinin; Cytarabine; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Immunohistochemistry; Intestinal Neoplasms; Kinetics; Mice; Mice, Transgenic; Neuroendocrine Tumors; Organophosphorus Compounds; Pyridazines; Receptors, GABA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

Topics: Animals; Bicuculline; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Mice; Midazolam; Models, Neurological; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Propofol; Pyridazines; Receptors, GABA-A

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Bicuculline; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Guinea Pigs; Hippocampus; Neural Inhibition; Neurons, Afferent; Organ Culture Techniques; Picrotoxin; Pyridazines; Receptors, AMPA; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols

Topics: Animals; Bicuculline; Cells, Cultured; Cerebellum; Cerebral Cortex; Electrophysiology; GABA Agonists; GABA-A Receptor Agonists; Isonicotinic Acids; Isoxazoles; Mice; Neurons; Oocytes; Patch-Clamp Techniques; Piperidines; Pyridazines; Receptors, GABA-A; Xenopus laevis

Topics: Action Potentials; Animals; Axons; Bicuculline; Dendrites; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Interneurons; Neural Inhibition; Patch-Clamp Techniques; Pyramidal Cells; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission; Time Factors

Topics: Action Potentials; Analgesics, Opioid; Anesthesia; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Antagonists; Male; Narcotic Antagonists; Neurons; Nociceptin; Nociceptin Receptor; Oligopeptides; Opioid Peptides; Peptide Fragments; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid; Signal Transduction; Thalamus; Urethane; Vasodilator Agents

Topics: Animals; Autoradiography; Bicuculline; Blotting, Western; Cerebral Cortex; Chlorides; Convulsants; Female; GABA Agonists; GABA Antagonists; Kinetics; Ligands; Male; Mice; Mice, Knockout; Muscimol; Pyridazines; Radioligand Assay; Receptors, GABA-A; Seizures

Topics: Anesthesia; Animals; Behavior, Animal; Bicuculline; Electric Stimulation; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Hyperalgesia; Interneurons; Ligands; Male; Motor Neurons; Muscle, Skeletal; Nociceptors; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Spinal Cord

Topics: Animals; Bicuculline; Carbachol; Choline O-Acetyltransferase; Cholinergic Agonists; Efferent Pathways; Electroencephalography; Electromyography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Immunohistochemistry; Kainic Acid; Kynurenic Acid; Male; Medulla Oblongata; Phytohemagglutinins; Pons; Proto-Oncogene Proteins c-fos; Pyridazines; Rats; Rats, Sprague-Dawley; Sleep, REM; Tegmentum Mesencephali; Wakefulness

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Bicuculline; Excitatory Amino Acid Antagonists; Extracellular Space; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Motor Activity; Neural Inhibition; Pyridazines; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Serotonin

Topics: Animals; Bicuculline; Binding, Competitive; Cells, Cultured; Cerebellum; Furosemide; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Patch-Clamp Techniques; Protein Subunits; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Zinc

Topics: Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Bicuculline; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; Glycine Agents; Infusions, Intravenous; Injections, Intraperitoneal; Isoflurane; Ketamine; Male; Picrotoxin; Propofol; Pulmonary Alveoli; Pyridazines; Rats; Rats, Sprague-Dawley; Strychnine

Topics: Action Potentials; Animals; Bicuculline; Dendrites; Evoked Potentials; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Interneurons; Neocortex; Neural Inhibition; Organophosphorus Compounds; Patch-Clamp Techniques; Pyramidal Cells; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Somatosensory Cortex; Synapses; Synaptic Transmission

Topics: Action Potentials; Animals; Bicuculline; GABA Antagonists; In Vitro Techniques; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Suprachiasmatic Nucleus; Time Factors

Topics: Animals; Bicuculline; Electrophysiology; Exocrine Glands; GABA Antagonists; Insecta; Larva; Neural Inhibition; NG-Nitroarginine Methyl Ester; Organophosphorus Compounds; Physical Stimulation; Predatory Behavior; Pyridazines; Rest; Swimming; Trigeminal Nerve; Xenopus laevis

Topics: Animals; Auditory Threshold; Bicuculline; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; In Vitro Techniques; Inferior Colliculi; Iontophoresis; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pyridazines; Rabbits; Rats; Rats, Long-Evans; Reaction Time; Receptors, GABA-A; Recruitment, Neurophysiological; Synapses

Topics: Action Potentials; Animals; Behavior, Animal; Bicuculline; Cerebellar Nuclei; GABA-A Receptor Antagonists; Haplorhini; Movement; Neurons; Pyridazines; Reaction Time; Time Factors

Topics: Anesthetics, Intravenous; Animals; Bicuculline; Cells, Cultured; Diazepam; Electrophysiology; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Hypothalamus; Intracellular Signaling Peptides and Proteins; Male; Neurons; Neuropeptides; Orexin Receptors; Orexins; Propofol; Pyridazines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, GABA-A; Receptors, Neuropeptide

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isonicotinic Acids; Lipoproteins; Magnesium; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium; Pyridazines; Rats; Seizures

Topics: Acetylcholine; Animals; Bicuculline; Bungarotoxins; Cadmium; Conotoxins; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Isoenzymes; Mecamylamine; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Neural Networks, Computer; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Picrotoxin; Protein Subunits; Pyridazines; Receptors, Nicotinic; Superior Colliculi

Topics: Acoustic Stimulation; Animals; Auditory Cortex; Auditory Perception; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gerbillinae; Iontophoresis; Male; Neurons; Pyridazines

Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chloride Channels; GABA Antagonists; Glutamic Acid; Hippocampus; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Small-Conductance Calcium-Activated Potassium Channels; Synaptic Transmission

Topics: Animals; Bicuculline; Body Weight; Efferent Pathways; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Phrenic Nerve; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Respiratory Mechanics; Respiratory Muscles; Spinal Cord Injuries; Stereotaxic Techniques; Strychnine; Vagotomy

Topics: Bicuculline; Binding, Competitive; Cell Line; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Humans; Neurons; Pyramidal Cells; Pyridazines; Receptors, GABA-A

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Bicuculline; Cyclopropanes; Enkephalin, Methionine; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Interneurons; Male; Mice; Mice, Inbred C57BL; Mossy Fibers, Hippocampal; Muscimol; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Pyridazines; Pyridinium Compounds; Receptors, GABA-A; Synaptic Transmission; Tetrodotoxin

Topics: Action Potentials; Animals; beta-Alanine; Bicuculline; Crotonates; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Furosemide; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Imidazoles; Microinjections; Mutation; Neural Inhibition; Neurons; Oocytes; Picrotoxin; Pyridazines; Rats; Receptors, GABA-A; Sesterterpenes; Taurine; Xenopus laevis; Zinc

Topics: Action Potentials; Animals; Bicuculline; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Hippocampus; Humans; Male; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A

Topics: Action Potentials; Animals; Bicuculline; Cats; Female; GABA Antagonists; Male; Neural Inhibition; Neurons; Posture; Psychomotor Performance; Pyramidal Tracts; Pyridazines; Receptors, GABA-A

Topics: Animals; Bicuculline; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Isoxazoles; Male; Medulla Oblongata; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Rats; Receptors, GABA-A; Synapses

Topics: Acoustic Stimulation; Anesthetics, Dissociative; Animals; Auditory Cortex; Bicuculline; Electrophysiology; Evoked Potentials, Auditory; GABA Antagonists; Gerbillinae; Iontophoresis; Ketamine; Male; Pyridazines; Spectrum Analysis

Topics: Animals; Bicuculline; Body Temperature; Dinoprostone; Dose-Response Relationship, Drug; Fever; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Male; Muscimol; Preoptic Area; Pyridazines; Rats; Rats, Wistar; Synaptic Transmission; Vasoconstriction

Topics: Acoustic Stimulation; Action Potentials; Animals; Bicuculline; Cochlear Nucleus; GABA Antagonists; Gerbillinae; Glycine Agents; Iontophoresis; Neural Inhibition; Neurons; Pyridazines; Reaction Time; Strychnine; Time Factors

Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Cerebellar Nuclei; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Kynurenic Acid; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Strychnine; Synapses

Topics: Age Factors; Animals; Animals, Newborn; Axons; Bicuculline; Drug Interactions; GABA Antagonists; Glycine Agents; Green Fluorescent Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Mice; Mice, Transgenic; Neural Inhibition; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channels, Inwardly Rectifying; Presynaptic Terminals; Pyridazines; Pyridines; Receptors, Metabotropic Glutamate; Retina; Retinal Bipolar Cells; Strychnine

Topics: Action Potentials; Animals; Bicuculline; Cell Culture Techniques; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Frontal Lobe; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Mice; Mice, Inbred ICR; Microelectrodes; Muscimol; Nerve Net; Neurons; Propylene Glycols; Pyridazines; Receptors, GABA-A; Tissue Array Analysis

Topics: Amino Acid Sequence; Animals; Bicuculline; Binding Sites; Chloride Channels; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA-A Receptor Antagonists; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Kinetics; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oocytes; Organophosphonates; Organophosphorus Compounds; Patch-Clamp Techniques; Phosphinic Acids; Protein Structure, Tertiary; Protein Subunits; Pyridazines; Rats; Receptors, GABA; Receptors, GABA-A; Sensitivity and Specificity; Sequence Homology, Amino Acid; Xenopus laevis

Topics: Animals; Bicuculline; Body Temperature; Dinoprostone; Fever; Functional Laterality; GABA Antagonists; GABA-A Receptor Antagonists; Male; Microinjections; Oxygen Consumption; Preoptic Area; Pyridazines; Rats; Rats, Wistar; Thermogenesis

Topics: Acetylcholine; Animals; Atropine; Bicuculline; Carbachol; Cholinergic Agonists; Cholinergic Fibers; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscarinic Antagonists; Neural Inhibition; Neural Pathways; Pons; Pyridazines; Rats; Rats, Long-Evans; Receptors, GABA-A; Reticular Formation; Sleep, REM; Synaptic Transmission

Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Bicuculline; Electrophysiology; Evoked Potentials; Female; In Vitro Techniques; Male; Medulla Oblongata; Mice; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridazines; Receptor, Adenosine A1; Respiratory Center; Respiratory Mechanics; Strychnine; Synaptic Transmission; Xanthines

Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Bicuculline; Electric Impedance; Electric Stimulation; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Neostriatum; Neurons; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Phosphinic Acids; Presynaptic Terminals; Propanolamines; Pyridazines; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Tetrodotoxin

Topics: Amygdala; Animals; Bicuculline; Brain; Cell Culture Techniques; Cerebellum; Chlorides; Diagnostic Imaging; Electric Stimulation; GABA Antagonists; Genetic Vectors; Hippocampus; Interneurons; Mice; Mice, Transgenic; Microscopy, Confocal; Neural Inhibition; Neurons; Pyridazines; Recombinant Fusion Proteins; Superior Colliculi; Synaptic Transmission; Transfection

Topics: Animals; Bicuculline; Blood Pressure; Excitatory Amino Acid Antagonists; GABA Agonists; GABA-A Receptor Antagonists; Glutamic Acid; Hypoxia; Kynurenic Acid; Male; Medulla Oblongata; Models, Neurological; Muscimol; Neurons; Phrenic Nerve; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Respiratory Mechanics; Sodium Cyanide; Splanchnic Nerves; Strychnine; Sympathetic Nervous System; Vagotomy

Topics: Animals; Animals, Newborn; Bicuculline; Biophysics; Calcium; Dendrites; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Methoxyhydroxyphenylglycol; Mice; Olfactory Bulb; Patch-Clamp Techniques; Pyridazines; Receptors, Metabotropic Glutamate; Sensory Receptor Cells

Topics: Acoustic Stimulation; Action Potentials; Animals; Auditory Cortex; Auditory Pathways; Auditory Threshold; Bicuculline; Biophysics; Chiroptera; Dose-Response Relationship, Drug; Echolocation; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Inferior Colliculi; Iontophoresis; Neural Inhibition; Neurons; Pitch Perception; Psychophysics; Pyridazines; Sound Localization

Topics: Anesthetics, Intravenous; Animals; Bicuculline; Cells, Cultured; Furosemide; GABA Antagonists; Inhibitory Postsynaptic Potentials; Male; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Propofol; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium Potassium Chloride Symporter Inhibitors; Solitary Nucleus; Synaptic Transmission

Topics: Amacrine Cells; Animals; Bicuculline; Boron Compounds; Cadmium Chloride; Calcium; Calcium Channel Blockers; Cells, Cultured; Dantrolene; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Imidazoles; Inhibitory Postsynaptic Potentials; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Membrane Potentials; Oxazoles; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anti-Anxiety Agents; Bicuculline; Cerebral Cortex; Cyclic Nucleotide-Gated Cation Channels; Desoxycorticosterone; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Agents; Homeostasis; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Patch-Clamp Techniques; Potassium Channels; Protein Subunits; Pyramidal Cells; Pyridazines; Pyrimidines; Receptors, GABA-A; Sodium Channel Blockers; Synapses; Tetrodotoxin; Up-Regulation; Valine

Topics: Animals; Bicuculline; GABA Antagonists; GABA-A Receptor Agonists; Glycine Agents; Hypercapnia; Male; Microinjections; Muscimol; Organophosphorus Compounds; Pyridazines; Rabbits; Receptors, GABA; Receptors, Glycine; Respiratory Center; Respiratory Physiological Phenomena; Strychnine; Time Factors

Topics: Acoustic Stimulation; Animals; Auditory Cortex; Auditory Perception; Bicuculline; Brain Mapping; Chiroptera; Echolocation; Electrophysiological Phenomena; Functional Laterality; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Neurons; Noise; Pyridazines

Topics: Animals; Bicuculline; Furosemide; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Motor Neurons; Picrotoxin; Presynaptic Terminals; Pyridazines; Receptors, GABA-A; Reflex, Monosynaptic; Spinal Cord; Synaptic Potentials; Turtles

Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bicuculline; Biological Clocks; Biophysical Phenomena; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Norepinephrine; Olfactory Bulb; Pyridazines; Quinoxalines; Rats; Receptors, Adrenergic; Valine

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Bicuculline; Cholinergic Agents; Corpus Striatum; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; Functional Laterality; GABA-A Receptor Antagonists; In Vitro Techniques; Interneurons; Light; Male; Models, Biological; Phosphinic Acids; Photic Stimulation; Propanolamines; Pyridazines; Rats; Rats, Long-Evans; Regression Analysis; Statistics, Nonparametric; Thalamus; Valine; Visual Pathways

Topics: Animals; Astrocytes; Bestrophins; Bicuculline; CA1 Region, Hippocampal; Cerebellum; Eye Proteins; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Ion Channels; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Pyridazines; Recombinant Fusion Proteins

Topics: Analgesics, Opioid; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Opioid, mu; Sodium Channel Blockers; Solitary Nucleus; Tetrodotoxin

Topics: Adenosine Triphosphate; Animals; Bicuculline; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cells, Cultured; Chelating Agents; Dendrites; Egtazic Acid; Embryo, Mammalian; Eukaryotic Initiation Factor-4G; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Gene Knockdown Techniques; Hippocampus; Humans; Immunoprecipitation; MAP Kinase Signaling System; Mutation; Neurons; Phosphorus Isotopes; Phosphorylation; Pyridazines; Rats; Rats, Sprague-Dawley; RNA Caps; RNA, Messenger; RNA, Small Interfering; Serine; Sodium Channel Blockers; Tetrodotoxin; TOR Serine-Threonine Kinases; Transfection

Topics: Action Potentials; Animals; Bicuculline; Brain Stem; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Motor Neurons; Picrotoxin; Pregnanolone; Protein Subunits; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Agents; Anesthetics, Local; Animals; Animals, Newborn; Bicuculline; Biophysics; Calcium; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Feedback, Physiological; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; In Vitro Techniques; Lidocaine; Lysine; Male; Mice; Mice, Transgenic; Monte Carlo Method; Neostriatum; Neural Inhibition; Neural Pathways; Neurons; Oxidopamine; Parkinsonian Disorders; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Wistar; Reaction Time; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission; Time Factors; Valine

Topics: Amino Acid Sequence; Animals; Bicuculline; Cells, Cultured; Corpus Striatum; Dopamine; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; HEK293 Cells; Humans; Male; Molecular Sequence Data; Mutation; Neurons; Picrotoxin; Protein Binding; Protein Subunits; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc

Topics: Animals; Bicuculline; Blood Pressure; Brain Ischemia; Cerebral Cortex; Docosahexaenoic Acids; GABA-A Receptor Antagonists; Injections, Intravenous; Laser-Doppler Flowmetry; Male; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Tritium; Vasodilation; Vasodilator Agents

Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials, Visual; GABA Antagonists; Mice; Mice, Inbred C57BL; Photic Stimulation; Pyridazines; Retina; Visual Cortex; Visual Pathways

Topics: Action Potentials; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Glycine Agents; In Vitro Techniques; Mice; Neurons; Picrotoxin; Preoptic Area; Pyridazines; Receptors, Glycine; Strychnine; Synapses; Taurine

Topics: Action Potentials; Adrenergic Fibers; Animals; Animals, Newborn; Bicuculline; GABA-A Receptor Antagonists; Glycine Agents; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Strychnine; Thoracic Vertebrae

Topics: Alkenes; Animals; Bicuculline; Cerebellum; Cholinergic Agents; Drug Interactions; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Gene Expression Regulation; Male; Neurons; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Piperidines; Pirenzepine; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Synaptic Transmission; Vestibular Nuclei

Topics: Animals; beta-Alanine; Bicuculline; Brain Stem; Central Nervous System Agents; Chlorine; GABA Agents; Hypoglossal Nerve; Midazolam; Motor Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Pentobarbital; Phosphinic Acids; Pregnanolone; Pyridazines; Pyridines; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Strychnine; Taurine; Tissue Culture Techniques

Topics: Animals; Bicuculline; Cells, Cultured; Drug Interactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Oocytes; Pyridazines; Receptors, GABA-A; Recovery of Function; Xenopus laevis

Topics: Animals; Bicuculline; Brain Stem; Diet, High-Fat; GABA Agonists; GABA Antagonists; Gastrointestinal Motility; Isoxazoles; Male; Neural Inhibition; Neurons; Pyridazines; Rats, Sprague-Dawley; Vagus Nerve

Topics: Animals; Bicuculline; Central Nervous System Agents; Female; gamma-Aminobutyric Acid; Neurons, Afferent; Patch-Clamp Techniques; Pregnanolone; Pyridazines; Rats, Sprague-Dawley; Receptors, GABA-A; Solitary Nucleus; Synaptic Transmission; Tissue Culture Techniques

Topics: Aminooxyacetic Acid; Animals; Anions; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Larva; Metamorphosis, Biological; Muscimol; Neurotransmitter Agents; Pyridazines; Receptors, GABA-A; Serotonin; Snails

Topics: Allosteric Regulation; Animals; Bicuculline; Binding, Competitive; Brain Tissue Transplantation; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Oocytes; Patch-Clamp Techniques; Protein Isoforms; Pyridazines; Receptors, GABA; Receptors, GABA-A; Substrate Specificity; Suramin; Xenopus

Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Hippocampus; Kindling, Neurologic; Male; Mice; Microinjections; Neural Inhibition; Neurosteroids; Pregnanolone; Pyridazines; Receptors, GABA-A; Seizures; Zinc

Topics: Animals; Behavior, Animal; Bicuculline; Discrimination, Psychological; GABA-A Receptor Antagonists; Hyperesthesia; Mice; Nerve Tissue Proteins; Neural Inhibition; Neurons, Afferent; Presynaptic Terminals; Pyridazines; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Sensory Receptor Cells; Skin; Spinal Cord Dorsal Horn; Touch