bicuculline has been researched along with piperidines in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (19.12) | 18.7374 |
| 1990's | 19 (27.94) | 18.2507 |
| 2000's | 21 (30.88) | 29.6817 |
| 2010's | 15 (22.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braestrup, C; Falch, E; Krogsgaard-Larsen, P; Nielsen, M | 2 |
| Andre, JM; Boulanger, T; Durant, F; Hoffmann, R; Rognan, D; Vercauteren, DP; Wermuth, CG | 1 |
| Falch, E; Kristiansen, U; Krogsgaard-Larsen, P; Lambert, JD | 1 |
| Fernández-Guasti, A; Larsson, K; Roldán-Roldán, G | 1 |
| Bardgett, ME; Gray, BC; Miller, JW | 1 |
| Dziki, M; Ikonomidou, C; Parada-Turska, J; Turski, WA; Urbanska, E | 1 |
| Ferrendelli, JA; Miller, JW | 1 |
| Kumasaka, Y; Ueki, S; Yamamoto, T | 1 |
| Altman, HJ; Normile, HJ | 1 |
| Byberg, JR; Curtis, DR; Falch, E; Gynther, BD; Hjeds, H; Krogsgaard-Larsen, P; Labouta, IM | 1 |
| Iversen, LL; Wong, EH | 1 |
| Beutler, JA; Brubaker, AN; Curtis, DR; Enna, SJ; Karbon, EW; Malik, R | 1 |
| Curtis, DR; Falch, E; Krogsgaard-Larsen, P; Nielsen, L | 1 |
| Curtis, DR; Gynther, BD; Malik, R | 1 |
| Curtis, DR; Gynther, BD | 2 |
| Curtis, DR; Leah, JD; Malik, R | 1 |
| Curtis, DR; Falch, E; Krogsgaard-Larsen, P; Lodge, D; Schousboe, A | 1 |
| Aghajanian, GK; Gellman, RL | 1 |
| Galvan, M; Piguet, P | 1 |
| Brown, MC; Liberman, MC; Sewell, WF; Sridhar, TS | 1 |
| Alreja, M | 1 |
| Rosenberg, HC; Tersigni, TJ | 1 |
| Sañudo-Peña, MC; Walker, JM | 2 |
| Gisselmann, G; Gottmann, K; Hatt, H; Mehrle, A | 1 |
| Almond, HR; Carmosin, RJ; Carson, JR; Pitis, PM; Stables, JP; Swinyard, EA; Vaught, JL; White, HS; Wolf, HH | 1 |
| Kouznetsova, M; Nistri, A | 2 |
| Bear, MF; Huganir, RL; Philpot, BD; Quinlan, EM | 1 |
| Aghajanian, GK; Marek, GJ | 1 |
| Fischer, H; Grass, K; Kraus, M; Lamberti, C; Philippu, A; Prast, H; Tran, MH | 1 |
| Blanchet, F; Gauchy, C; Glowinski, J; Kemel, ML; Pérez, S; Soubrié, P | 1 |
| Linden, DJ; Takahashi, KA | 1 |
| Cheer, JF; Kendall, DA; Marsden, CA; Mason, R | 1 |
| Ebert, B; Fjalland, B; Hansen, SL; Kristiansen, U | 1 |
| Boscan, P; Kasparov, S; Paton, JF | 1 |
| D'Hooge, R; De Deyn, PP; Marescau, B; Van Bogaert, PP; Van de Vijver, G; Vanholder, R | 1 |
| Ito, I; Kato, Y; Kawakami, R; Shigemoto, R; Shinohara, Y; Sugiyama, H | 1 |
| Ogier, R; Raggenbass, M | 1 |
| Andrade, R; Béïque, JC; Chapin-Penick, EM; Mladenovic, L | 1 |
| Bale, AS; Carpenter-Hyland, EP; Chandler, LJ; Tu, Y; Woodward, JJ | 1 |
| Bianchi, C; Della Corte, L; Fantin, M; Manzalini, M; Marti, M; Morari, M | 1 |
| Ballini, C; Blandina, P; Cenni, G; Della Corte, L; Formigli, L; Giannoni, P; Mackie, K; Mannaioni, PF; Nosi, D; Passani, MB | 1 |
| Marti, M; Morari, M; Trapella, C; Viaro, R | 1 |
| Chen, Q; Dong, L; Fu, CY; Ni, JM; Wang, R; Zhao, YL | 1 |
| Ma, YL; Stephens, GJ; Weston, SE; Whalley, BJ | 1 |
| Luna, VM; Schoppa, NE | 1 |
| Kovacs, FE; Szabo, B; Urbanski, MJ | 1 |
| Andó, RD; Sperlágh, B; Sylvester Vizi, E; Windisch, K | 1 |
| Bernard, JF; Hamon, M; Laguzzi, R; Mandjee, N; Netzer, F; Sévoz-Couche, C; Verberne, AJ | 1 |
| Hasanein, P; Keshavarz, S; Moghaddam, AH; Rezvani, ME; Roohbakhsh, A | 1 |
| Bernardi, G; Castelli, M; Cavasinni, F; Centonze, D; De Chiara, V; Errico, F; Mataluni, G; Musella, A; Rossi, S; Sacchetti, L; Siracusano, A; Usiello, A | 1 |
| Hillard, CJ; Ho, WS; Patel, S; Roberts, CJ; Stuhr, KL; Thompson, JR | 1 |
| Ali, U; Feng, JJ; Gui, ZH; Hui, YP; Li, LB; Liu, J; Niu, XL; Wu, ZH; Zhang, QJ | 1 |
| Adermark, L | 1 |
| Le, L; Meaney, DF; Spaethling, J | 1 |
| Eisenach, JC; Hayashida, K; Kimura, M; Obata, H; Saito, S | 1 |
| Coimbra, NC; Crippa, JA; Freitas, RL; Hallak, JE; Salgado-Rohner, CJ | 1 |
| Aguiar, JC; Guimarães, FS; Lisboa, SF; Magesto, AC; Resstel, LB | 1 |
| Aissouni, Y; Chalus, M; Courteix, C; Dupuis, A; Eschalier, A; Hernández, A; Marin, P; Pelissier, T; Pichon, X; Privat, AM; Wattiez, AS | 1 |
| Everitt, BJ; Milton, AL; Ratano, P | 1 |
| Jin, CY; Pertovaara, A; Viisanen, H; Wei, H; You, HJ | 1 |
| Jang, HJ; Joo, K; Kim, MJ; Lee, C; Rhie, DJ | 1 |
| Chen, SR; Pan, HL; Zhu, Y | 1 |
| Coimbra, NC; Dos Anjos-Garcia, T; Falconi-Sobrinho, LL; Ullah, F | 1 |
| Antero, LS; Lisboa, SF; Reis, DG; Resstel, LB; Spiacci, GB | 1 |
68 other study(ies) available for bicuculline and piperidines
| Article | Year |
|---|---|
Partial agonists for brain GABA/benzodiazepine receptor complex.
Topics: Animals; Benzodiazepines; Bicuculline; Brain; Crotonates; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, Drug; Sulfonic Acids | 1979 |
Structure and molecular modeling of GABAA receptor antagonists.
Topics: Alkaloids; Androstanes; Azasteroids; Azepines; Bicuculline; Crystallization; Dibenzazepines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Heterocyclic Compounds, 4 or More Rings; Heterocyclic Compounds, Bridged-Ring; Isoxazoles; Lactones; Models, Molecular; Molecular Conformation; Molecular Structure; Piperidines; Pyridazines; Receptors, GABA-A; Structure-Activity Relationship; Tubocurarine; X-Ray Diffraction | 1992 |
Electrophysiological studies of the GABAA receptor ligand, 4-PIOL, on cultured hippocampal neurones.
Topics: Animals; Bicuculline; Cells, Cultured; Female; Hippocampus; Isonicotinic Acids; Isoxazoles; Membrane Potentials; Neurons; Piperidines; Pregnancy; Rats; Receptors, GABA-A; Spinal Cord | 1991 |
Anxiolytics reverse the acceleration of ejaculation resulting from enforced intercopulatory intervals in rats.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Anxiety Agents; Arousal; Benzodiazepines; Bicuculline; Buspirone; Dose-Response Relationship, Drug; Ejaculation; Male; Piperidines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Receptors, Serotonin; Sexual Behavior, Animal; Social Environment | 1991 |
The role of the laterodorsal tegmental nucleus of the rat in experimental seizures.
Topics: Alcian Blue; Animals; Baclofen; Bicuculline; Female; Histocytochemistry; In Vitro Techniques; Microinjections; Pentylenetetrazole; Piperidines; Rats; Rats, Inbred Strains; Seizures; Strychnine; Tegmentum Mesencephali; Thalamic Nuclei | 1991 |
Excitatory amino acid antagonists protect mice against seizures induced by bicuculline.
Topics: Animals; Bicuculline; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; Muscimol; Pipecolic Acids; Piperazines; Piperidines; Receptors, Amino Acid; Receptors, Cell Surface; Seizures | 1990 |
Characterization of GABAergic seizure regulation in the midline thalamus.
Topics: Animals; Baclofen; Bicuculline; Electroencephalography; Epilepsy; Female; Flurazepam; gamma-Aminobutyric Acid; Pentobarbital; Pentylenetetrazole; Piperidines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thalamic Nuclei | 1990 |
Behavioral analysis of zopiclone on the basis of their discriminative stimulus properties in the rat.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Behavior, Animal; Benzodiazepines; Bicuculline; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Hypnotics and Sedatives; Male; Muscimol; Naphthyridines; Pentylenetetrazole; Piperazines; Piperidines; Rats; Rats, Inbred WKY; Ritanserin; Serotonin Antagonists; Sulfur Compounds | 1989 |
Evidence for a possible interaction between noradrenergic and serotonergic neurotransmission in the retrieval of a previously learned aversive habit in mice.
Topics: Animals; Avoidance Learning; Bicuculline; Brain; Haloperidol; Male; Memory; Mental Recall; Mice; Mice, Inbred Strains; Phenoxybenzamine; Piperidines; Propranolol; Receptors, Adrenergic; Receptors, Serotonin; Retention, Psychology; Scopolamine; Synaptic Transmission; Tranquilizing Agents | 1987 |
Synthesis and biological activity of a GABAA agonist which has no effect on benzodiazepine binding and of structurally related glycine antagonists.
Topics: Animals; Bicuculline; Brain Chemistry; Chemical Phenomena; Chemistry; Diazepam; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Isoxazoles; Oxazoles; Piperidines; Pyrrolidines; Rats; Receptors, GABA-A; Synaptic Membranes | 1987 |
Modulation of [3H]diazepam binding in rat cortical membranes by GABAA agonists.
Topics: Androstanes; Animals; Azasteroids; Bicuculline; Cell Membrane; Cerebral Cortex; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isonicotinic Acids; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, GABA-A; Taurine | 1985 |
Securinine alkaloids: a new class of GABA receptor antagonist.
Topics: Alkaloids; Animals; Azepines; Bicuculline; Cats; Central Nervous System; Convulsants; Female; Heterocyclic Compounds, 4 or More Rings; Heterocyclic Compounds, Bridged-Ring; Lactones; Mice; Mice, Inbred ICR; Piperidines; Receptors, GABA-A; Seizures; Stimulation, Chemical | 1985 |
GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol.
Topics: Animals; Bicuculline; Brain; Cats; Chemical Phenomena; Chemistry; Diazepam; gamma-Aminobutyric Acid; Isoxazoles; Molecular Conformation; Muscimol; Neurons; Oxazolidinones; Piperidines; Rats; Receptors, GABA-A; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Synaptic Membranes | 1985 |
A pharmacological study of group I muscle afferent terminals and synaptic excitation in the intermediate nucleus and Clarke's column of the cat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Cats; gamma-Aminobutyric Acid; Interneurons; Muscles; Neurons, Afferent; Piperidines; Spinal Cord; Synaptic Transmission | 1986 |
On the probable absence of GABA receptors on the terminations of motor axon collaterals in the cat spinal cord.
Topics: Animals; Anterior Horn Cells; Bicuculline; Cats; gamma-Aminobutyric Acid; Interneurons; Motor Neurons; Piperidines; Receptors, GABA-A; Synaptic Transmission | 1986 |
Divalent cations reduce depolarization of primary afferent terminations by GABA.
Topics: Action Potentials; Animals; Bicuculline; Cations, Divalent; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Interneurons; Membrane Potentials; Muscles; Neurons, Afferent; Piperidines; Spinal Cord | 1987 |
Two or more conformations of benzodiazepine receptors depending on GABA receptors and other variables.
Topics: Animals; Benzodiazepines; Bicuculline; Brain; Diazepam; gamma-Aminobutyric Acid; Macromolecular Substances; Male; Muscimol; Piperidines; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Structure-Activity Relationship; Synaptic Membranes | 1980 |
The effects of naloxone, morphine and methionine enkephalinamide on Ia afferent terminations in the cat spinal cord.
Topics: Afferent Pathways; Animals; Bicuculline; Cats; Electric Stimulation; Enkephalin, Methionine; gamma-Aminobutyric Acid; Morphine; Muscles; Naloxone; Piperidines; Procaine; Reflex, Monosynaptic; Synapses | 1984 |
Piperidine-4-sulphonic acid, a new specific GABA agonist.
Topics: Animals; Astrocytes; Bicuculline; Cats; gamma-Aminobutyric Acid; Mice; Neurons; Piperidines; Receptors, Drug; Spinal Cord; Structure-Activity Relationship | 1980 |
Serotonin2 receptor-mediated excitation of interneurons in piriform cortex: antagonism by atypical antipsychotic drugs.
Topics: Action Potentials; Animals; Antipsychotic Agents; Bicuculline; Cerebral Cortex; Chlorpromazine; Clozapine; Electrophysiology; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Interneurons; Isoxazoles; Male; Membrane Potentials; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin Antagonists | 1994 |
Transient and long-lasting actions of 5-HT on rat dentate gyrus neurones in vitro.
Topics: Animals; Bicuculline; Dioxins; Electrophysiology; Excitatory Amino Acid Antagonists; Fluorobenzenes; GABA Antagonists; Glutamic Acid; Hippocampus; Indoles; Long-Term Potentiation; Male; Piperidines; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Spiro Compounds; Tetrodotoxin | 1994 |
A novel cholinergic "slow effect" of efferent stimulation on cochlear potentials in the guinea pig.
Topics: Acoustic Stimulation; Animals; Atropine; Bicuculline; Cochlea; Decamethonium Compounds; Dose-Response Relationship, Drug; Efferent Pathways; Electric Stimulation; Guinea Pigs; Hair Cells, Auditory, Outer; Hexamethonium; Membrane Potentials; Models, Neurological; Nerve Fibers; Piperidines; Strychnine; Time Factors; Vestibulocochlear Nerve | 1995 |
Excitatory actions of serotonin on GABAergic neurons of the medial septum and diagonal band of Broca.
Topics: Animals; Bicuculline; Brain; Electrophysiology; Evoked Potentials; Extracellular Space; Fluorobenzenes; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Piperidines; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Tetrodotoxin; Visual Pathways | 1996 |
Local pressure application of cannabinoid agonists increases spontaneous activity of rat substantia nigra pars reticulata neurons without affecting response to iontophoretically-applied GABA.
Topics: Action Potentials; Analgesics; Analysis of Variance; Animals; Benzoxazines; Bicuculline; Cannabinoids; Cyclohexanols; gamma-Aminobutyric Acid; Iontophoresis; Male; Morpholines; Naphthalenes; Neurons; Piperidines; Pressure; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Substantia Nigra | 1996 |
Role of the subthalamic nucleus in cannabinoid actions in the substantia nigra of the rat.
Topics: Analgesics; Animals; Benzoxazines; Bicuculline; Cannabinoids; GABA Antagonists; Male; Morpholines; Naphthalenes; Neural Pathways; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Substantia Nigra; Thalamic Nuclei | 1997 |
Presynaptic control of subunit composition of NMDA receptors mediating synaptic plasticity.
Topics: Animals; Bicuculline; Cells, Cultured; Coculture Techniques; Embryo, Mammalian; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Kinetics; Macromolecular Substances; Magnesium; N-Methylaspartate; Neuronal Plasticity; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Polymerase Chain Reaction; Presynaptic Terminals; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 1997 |
Aroyl(aminoacyl)pyrroles, a new class of anticonvulsant agents.
Topics: Anesthesia; Animals; Anticonvulsants; Bicuculline; Calcium; Cerebellum; Electroshock; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Piperidines; Potassium; Pyrroles; Rats; Seizures; Structure-Activity Relationship; Veratridine | 1997 |
Modulation by substance P of synaptic transmission in the mouse hippocampal slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Mice; Microelectrodes; Patch-Clamp Techniques; Piperidines; Pyramidal Cells; Quinuclidines; Receptors, Neurokinin-1; Substance P; Synaptic Transmission; Tetrodotoxin; Time Factors | 1998 |
A novel neurotransmitter system involved in the control of motor behavior by the basal ganglia.
Topics: Action Potentials; Analgesics; Animals; Basal Ganglia; Benzoxazines; Bicuculline; Cannabinoids; Cyclohexanols; Dopamine; Dopamine Agonists; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Morpholines; Motor Neurons; Naphthalenes; Nerve Degeneration; Neurotransmitter Agents; Oxidopamine; Piperidines; Pyrazoles; Quinpirole; Rats; Rimonabant; Sympatholytics; Thalamic Nuclei | 1998 |
Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Animals, Suckling; Bicuculline; Cycloheximide; Darkness; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation, Developmental; Glycine; Kynurenic Acid; Light; Male; Models, Neurological; Nerve Tissue Proteins; Neuronal Plasticity; Optic Nerve; Photic Stimulation; Piperidines; Protein Synthesis Inhibitors; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sensory Deprivation; Synapses; Vision, Ocular; Visual Cortex; Zinc | 1999 |
Serotonin, via 5-HT2A receptors, increases EPSCs in layer V pyramidal cells of prefrontal cortex by an asynchronous mode of glutamate release.
Topics: Animals; Bicuculline; Calcium; Calcium-Binding Proteins; Dendrites; Electric Stimulation; Excitatory Postsynaptic Potentials; Fluorobenzenes; Free Radical Scavengers; GABA Antagonists; Glutamic Acid; Indophenol; Male; Membrane Glycoproteins; Nerve Tissue Proteins; Organ Culture Techniques; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Strontium; Synaptotagmins | 1999 |
Histaminergic neurons modulate acetylcholine release in the ventral striatum: role of H3 histamine receptors.
Topics: Acetylcholine; Animals; Bicuculline; Dopamine; Dopamine Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Histamine; Histamine Antagonists; Ligands; Male; Methylhistidines; Neurons; Perfusion; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Stereotaxic Techniques; Time Factors; Visual Cortex | 1999 |
Control by GABA and tachykinins of the evoked release of acetylcholine in striatal compartments under different modalities of NMDA receptor stimulation.
Topics: Acetylcholine; Animals; Benzamides; Bicuculline; Cell Compartmentation; Cells, Cultured; Corpus Striatum; Dopamine Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; N-Methylaspartate; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-2; Stimulation, Chemical; Sulpiride; Tachykinins | 2000 |
Cannabinoid receptor modulation of synapses received by cerebellar Purkinje cells.
Topics: Animals; Axons; Benzoxazines; Bicuculline; Calcium Channel Blockers; Cannabinoids; Cerebellum; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; In Vitro Techniques; Male; Membrane Potentials; Morpholines; Naphthalenes; Patch-Clamp Techniques; Piperidines; Presynaptic Terminals; Purkinje Cells; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Synapses | 2000 |
Facilitation of cholinergic transmission by substance P methyl ester in the mouse hippocampal slice preparation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Carbachol; Cholinergic Agonists; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Hippocampus; Male; Membrane Potentials; Mice; Patch-Clamp Techniques; Piperidines; Pyramidal Cells; Quinuclidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Substance P; Tetrodotoxin; Valine | 2000 |
Lack of response suppression follows repeated ventral tegmental cannabinoid administration: an in vitro electrophysiological study.
Topics: Action Potentials; Animals; Bicuculline; Cannabinoids; Dopamine; Dronabinol; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reward; Rimonabant; Ventral Tegmental Area | 2000 |
Effects of GABA(A) receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositions.
Topics: Animals; Bicuculline; Cells, Cultured; Cerebellum; Cerebral Cortex; Electrophysiology; GABA Agonists; GABA-A Receptor Agonists; Isonicotinic Acids; Isoxazoles; Mice; Neurons; Oocytes; Patch-Clamp Techniques; Piperidines; Pyridazines; Receptors, GABA-A; Xenopus laevis | 2001 |
Somatic nociception activates NK1 receptors in the nucleus tractus solitarii to attenuate the baroreceptor cardiac reflex.
Topics: Animals; Baroreflex; Bicuculline; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Microinjections; Neural Inhibition; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Pain Measurement; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Neurokinin-1; Solitary Nucleus; Substance P | 2002 |
Involvement of voltage- and ligand-gated Ca2+ channels in the neuroexcitatory and synergistic effects of putative uremic neurotoxins.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Calcium Channels; Cells, Cultured; Drug Synergism; Excitatory Amino Acid Antagonists; GABA Antagonists; Guanidines; Membrane Potentials; Mice; Neurons; Nickel; Piperidines; Potassium Channel Blockers; Seizures; Spermine; Spinal Cord; Succinates; Synapses; Tetraethylammonium; Tetrodotoxin; Uremia | 2003 |
Asymmetrical allocation of NMDA receptor epsilon2 subunits in hippocampal circuitry.
Topics: Animals; Bicuculline; Dendrites; Denervation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Patch-Clamp Techniques; Perforant Pathway; Phenols; Piperidines; Pyramidal Cells; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses | 2003 |
Action of tachykinins in the rat hippocampus: modulation of inhibitory synaptic transmission.
Topics: Animals; Animals, Newborn; Bicuculline; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Interneurons; Membrane Potentials; Neural Inhibition; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuropeptides; Patch-Clamp Techniques; Peptide Fragments; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Synaptic Transmission; Tachykinins; Time Factors | 2003 |
Serotonergic facilitation of synaptic activity in the developing rat prefrontal cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Bicuculline; Fluorobenzenes; GABA-A Receptor Antagonists; Glutamic Acid; Indoles; Lidocaine; Male; Patch-Clamp Techniques; Phenols; Pindolol; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors | 2004 |
Alterations in glutamatergic and gabaergic ion channel activity in hippocampal neurons following exposure to the abused inhalant toluene.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Bicuculline; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Immunohistochemistry; Ion Channel Gating; Ion Channels; Membrane Potentials; Microscopy, Confocal; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solvents; Symporters; Time Factors; Toluene | 2005 |
Striatal glutamate release evoked in vivo by NMDA is dependent upon ongoing neuronal activity in the substantia nigra, endogenous striatal substance P and dopamine.
Topics: Adrenergic Agents; Animals; Benzazepines; Bicuculline; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Glutamic Acid; Magnesium; Male; N-Methylaspartate; Neurons; Oxidopamine; Piperidines; Potassium Chloride; Quinuclidines; Raclopride; Rats; Rats, Sprague-Dawley; Substance P; Substantia Nigra; Tetrodotoxin; Time Factors | 2005 |
Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain.
Topics: Analysis of Variance; Animals; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Modulators; Cannabinoids; Cell Differentiation; Chromatography, High Pressure Liquid; Endocannabinoids; GABA Antagonists; gamma-Aminobutyric Acid; Histamine; Hypothalamus; Immunohistochemistry; Male; Microdialysis; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Time Factors; Wakefulness | 2006 |
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway.
Topics: Animals; Antiparkinson Agents; Benzimidazoles; Bicuculline; Drug Synergism; Drug Therapy, Combination; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Injections; Levodopa; Male; Microdialysis; Motor Activity; Neural Pathways; Nociceptin Receptor; Oxidopamine; Parkinsonian Disorders; Perfusion; Piperidines; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium Channel Blockers; Stereotaxic Techniques; Substantia Nigra; Tetrodotoxin; Thalamus | 2007 |
In vivo characterization of the effects of human hemokinin-1 and human hemokinin-1(4-11), mammalian tachykinin peptides, on the modulation of pain in mice.
Topics: Analgesics; Animals; Benzamides; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Humans; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Tachykinins; Tropanes | 2008 |
The phytocannabinoid Delta(9)-tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum.
Topics: Animals; Benzoxazines; Bicuculline; Cannabinoids; Cerebellum; Dronabinol; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Morpholines; Naphthalenes; Patch-Clamp Techniques; Piperidines; Purkinje Cells; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Synapses; Synaptic Transmission | 2008 |
GABAergic circuits control input-spike coupling in the piriform cortex.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Cerebral Cortex; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Lysine; Models, Neurological; Nerve Net; Neurons; Olfactory Pathways; Patch-Clamp Techniques; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Triazines | 2008 |
Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling.
Topics: Aniline Compounds; Animals; Animals, Newborn; Arachidonic Acids; Benzamides; Bicuculline; Biophysics; Calcium; Calcium Signaling; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Carbamates; Cerebellum; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluoresceins; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycerides; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lactones; Mice; Muscimol; Orlistat; Patch-Clamp Techniques; Piperidines; Purkinje Cells; Pyrazoles; Quinoxalines; Rimonabant; Signal Transduction; Synapses; Valine | 2009 |
Neurochemical evidence that stimulation of CB1 cannabinoid receptors on GABAergic nerve terminals activates the dopaminergic reward system by increasing dopamine release in the rat nucleus accumbens.
Topics: Animals; Benzoxazines; Bicuculline; Dopamine; Electric Stimulation; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Morpholines; Naphthalenes; Nerve Endings; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reward | 2009 |
Inhibition of the bradycardic component of the von Bezold-Jarisch reflex and carotid chemoreceptor reflex by periaqueductal gray stimulation: involvement of medullary receptors.
Topics: Animals; Bicuculline; Biguanides; Bradycardia; Carotid Arteries; Chemoreceptor Cells; GABA Antagonists; Granisetron; Immunohistochemistry; Male; Microinjections; Parasympathetic Nervous System; Periaqueductal Gray; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Neurokinin-1; Receptors, Serotonin, 5-HT3; Reflex; Serotonin Agents; Solitary Nucleus; Sympathetic Nervous System; Tetrazoles | 2009 |
Role of endocannabinoid system in the ventral hippocampus of rats in the modulation of anxiety-like behaviours.
Topics: Amidohydrolases; Animals; Anxiety; Baclofen; Behavior, Animal; Benzamides; Bicuculline; Cannabinoid Receptor Modulators; Carbamates; Dose-Response Relationship, Drug; Endocannabinoids; GABA Antagonists; Hippocampus; Male; Maze Learning; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2009 |
Voluntary exercise and sucrose consumption enhance cannabinoid CB1 receptor sensitivity in the striatum.
Topics: Animals; Baclofen; Bicuculline; Corpus Striatum; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Exploratory Behavior; Food Preferences; GABA Agonists; GABA Antagonists; Inhibitory Postsynaptic Potentials; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Physical Conditioning, Animal; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reward; Statistics, Nonparametric; Stress, Psychological; Sucrose; Time Factors | 2010 |
Endocannabinoid modulation of hyperaemia evoked by physiologically relevant stimuli in the rat primary somatosensory cortex.
Topics: Animals; Arachidonic Acids; Benzoxazines; Bicuculline; Cannabinoid Receptor Modulators; Endocannabinoids; Functional Laterality; Glycerides; Hyperemia; Male; Morpholines; Naphthalenes; Piperidines; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Somatosensory Cortex; Vibrissae | 2010 |
The pyramidal neurons in the medial prefrontal cortex show decreased response to 5-hydroxytryptamine-3 receptor stimulation in a rodent model of Parkinson's disease.
Topics: Action Potentials; Analysis of Variance; Animals; Bicuculline; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Indoles; Male; Oxidopamine; Parkinson Disease; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Serotonin Agents; Statistics, Nonparametric; Substantia Nigra; Tropisetron; Tyrosine 3-Monooxygenase | 2011 |
Modulation of endocannabinoid-mediated long-lasting disinhibition of striatal output by cholinergic interneurons.
Topics: Animals; Animals, Newborn; Benzazepines; Bicuculline; Biophysics; Cannabinoid Receptor Modulators; Cholinergic Agents; Chromones; Corpus Striatum; Dopamine Antagonists; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Interneurons; Long-Term Potentiation; Models, Neurological; Neural Inhibition; Piperidines; Pyrazoles; Pyridines; Rats; Rats, Wistar; Signal Transduction; Sulpiride; Valine | 2011 |
NMDA receptor mediated phosphorylation of GluR1 subunits contributes to the appearance of calcium-permeable AMPA receptors after mechanical stretch injury.
Topics: Animals; Bicuculline; Blotting, Western; Brain Injuries; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Antagonists; Phenols; Phosphorylation; Piperidines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2012 |
Relief of hypersensitivity after nerve injury from systemic donepezil involves spinal cholinergic and γ-aminobutyric acid mechanisms.
Topics: Animals; Atropine; Bicuculline; Cholinergic Agents; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; GABA Agents; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Indans; Male; Mecamylamine; Neuralgia; Nicotinic Antagonists; Organophosphorus Compounds; Parasympatholytics; Peripheral Nerve Injuries; Piperidines; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2013 |
Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei: role of the endocannabinoid
Topics: Analysis of Variance; Animals; Bicuculline; Defense Mechanisms; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Antagonists; Hyperalgesia; Hypothalamus; Instinct; Male; Microinjections; Pain Measurement; Pain Threshold; Panic; Piperidines; Prefrontal Cortex; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, GABA-A | 2013 |
Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats.
Topics: Animals; Anxiety; Apomorphine; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; GABA-A Receptor Antagonists; Male; Maze Learning; Nitric Oxide Synthase; Oxadiazoles; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2013 |
Disruption of 5-HT2A receptor-PDZ protein interactions alleviates mechanical hypersensitivity in carrageenan-induced inflammation in rats.
Topics: Animals; Bicuculline; Carrageenan; Disks Large Homolog 4 Protein; Fluorobenzenes; Fluoxetine; Hyperalgesia; Inflammation; Injections; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Pain; Peptides; Piperidines; Posterior Horn Cells; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists | 2013 |
The CB1 receptor antagonist AM251 impairs reconsolidation of pavlovian fear memory in the rat basolateral amygdala.
Topics: Amidohydrolases; Animals; Auditory Perception; Basolateral Nuclear Complex; Benzamides; Bicuculline; Cannabinoid Receptor Antagonists; Carbamates; Conditioning, Classical; Electroshock; Enzyme Inhibitors; Fear; GABA-A Receptor Antagonists; Male; Memory; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, GABA-A | 2014 |
Histamine in the locus coeruleus promotes descending noradrenergic inhibition of neuropathic hypersensitivity.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; Animals; Benzothiazoles; Bicuculline; GABA-A Receptor Antagonists; Histamine; Histamine H2 Antagonists; Hot Temperature; Hyperalgesia; Imidazoles; Indans; Locus Coeruleus; Male; Neuralgia; Phenoxypropanolamines; Physical Stimulation; Piperidines; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Histamine; Spinal Nerves | 2014 |
GluN2B-containing N-methyl-D-aspartate receptors compensate for the inhibitory control of synaptic plasticity during the early critical period in the rat visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Bicuculline; Diazepam; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Modulators; GABA-A Receptor Antagonists; Gene Expression Regulation, Developmental; Long-Term Potentiation; Male; Neural Inhibition; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Visual Cortex | 2015 |
Muscarinic receptor subtypes differentially control synaptic input and excitability of cerebellum-projecting medial vestibular nucleus neurons.
Topics: Alkenes; Animals; Bicuculline; Cerebellum; Cholinergic Agents; Drug Interactions; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Gene Expression Regulation; Male; Neurons; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Piperidines; Pirenzepine; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Synaptic Transmission; Vestibular Nuclei | 2016 |
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Topics: Animals; Arachidonic Acids; Bicuculline; Disease Models, Animal; Endocannabinoids; Escape Reaction; GABA-A Receptor Antagonists; Male; Panic Disorder; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, GABA-A; TRPV Cation Channels; Ventromedial Hypothalamic Nucleus | 2017 |
Dorsal hippocampus cannabinoid type 1 receptors modulate the expression of contextual fear conditioning in rats: Involvement of local glutamatergic/nitrergic and GABAergic neurotransmissions.
Topics: Animals; Bicuculline; Conditioning, Psychological; Emotions; Fear; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Male; Nitric Oxide; Nitric Oxide Synthase; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Synaptic Transmission | 2016 |