bicuculline has been researched along with pentobarbital in 163 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 67 (41.10) | 18.7374 |
| 1990's | 65 (39.88) | 18.2507 |
| 2000's | 23 (14.11) | 29.6817 |
| 2010's | 7 (4.29) | 24.3611 |
| 2020's | 1 (0.61) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Dray, A; Gonye, TJ; Oakley, NR | 1 |
| Kuschinsky, W; Wahl, M | 1 |
| Duggan, AW; Headley, PM; Lodge, D | 1 |
| Bowery, NG; Dray, A | 2 |
| Evans, RH | 1 |
| Franco, S; Schlosser, W | 1 |
| Sastry, BR | 1 |
| Brown, DA; Constanti, A | 1 |
| Fukushima, H; Tsuchiya, T | 1 |
| Nicoll, RA | 1 |
| Bartolini, A; Ghelardini, C; Giotti, A; Malcangio, M; Malmberg-Aiello, P | 1 |
| Atkinson, AE; Barnard, EA; Beadle, DJ; Bermudez, I; Darlison, MG; Earley, FG; King, LA; Possee, RD | 1 |
| Gillis, RA; Pineo, S; Taveira Da Silva, AM | 1 |
| Lin, WC; Watanabe, K; Yano, S | 2 |
| Cairns, A; Schneiderman, JH; Sterling, CA | 1 |
| Berger, T; Kettenmann, H; Schnitzer, J; Walz, W | 1 |
| Arakawa, O; Nakahiro, M; Narahashi, T | 1 |
| Dolin, SJ; Morris, PJ; Smith, MB; Soar, J | 1 |
| Long, SK; van Wilgenburg, H; Wesselman, JP | 1 |
| Araki, Y; Gomita, Y; Ichimaru, Y; Moriyama, M | 1 |
| Asprodini, EK; Rainnie, DG; Shinnick-Gallagher, P | 1 |
| Kaneko, A; Suzuki, S; Tachibana, M | 1 |
| Miledi, R; Polenzani, L; Woodward, RM | 1 |
| Blakeman, DP; Im, WB | 1 |
| MacIver, MB; Mody, I; Tanelian, DL | 1 |
| Fu, QG; Sandkühler, J; Willmann, E | 1 |
| Akaike, N; Nakagawa, T; Nakaye, T; Shirasaki, T; Wakamori, M | 1 |
| Hori, S; Ito, T; Kadokawa, T; Miura, Y; Miyahara, T; Shimada, J | 1 |
| Albertson, TE; Joy, RM | 1 |
| Dashkin, AN; Garashchuk, OA; Valeev, AE | 1 |
| Fincher, AS; Frye, GD; Griffith, WH; Lorenzetti, M; Trzeciakowski, J | 1 |
| Ferrendelli, JA; Miller, JW | 1 |
| Kim, KH; Takeuchi, H | 1 |
| Paul, SM; Schwartz, RD; Skolnick, P; Suzdak, PD | 1 |
| Bourque, CW; Randle, JC; Renaud, LP | 1 |
| Chernevskaia, NI; Valeev, AE; Vrublevskiĭ, SV | 1 |
| Smith, GK; Suzuki, SS | 1 |
| Atsoggiu, T; Biggio, G; Concas, A; Pepitoni, S; Toffano, G | 1 |
| Dudek, BC; Phillips, TJ | 1 |
| Kamei, J; Kasuya, Y; Ogawa, M | 1 |
| Abel, MS; Blume, AJ; Garrett, KM | 1 |
| Kulkarni, SK; Ticku, MK | 1 |
| Nistri, A; Sivilotti, L | 1 |
| Gale, RG; Little, HJ; Nutt, DJ; Standing, BL; Taylor, SC | 1 |
| Hara, S; Morioka, S; Satoh, K; Yanagihara, S | 1 |
| De Medici, D; Gatta, F; Longo, VG; Massotti, M | 1 |
| Mehta, AK; Ticku, MK | 2 |
| Barnard, EA; Blair, LA; Dionne, VE; Levitan, ES | 1 |
| Eysel, UT; Pape, HC; Van Schayck, R | 2 |
| Gross, RA; Macdonald, RL; Weddle, MG | 1 |
| Andres-Trelles, F; Orviz, P | 1 |
| Duce, IR; Scott, RH | 1 |
| McGarrick, JD; Stone, TW; Thexton, AJ | 1 |
| Iwai, S; Shirakawa, J; Tanaka, C; Taniyama, K | 1 |
| Olsen, RW; Snowman, AM | 1 |
| Rastogi, SK; Ticku, MK | 1 |
| Scholfield, CN; Steel, L | 1 |
| Lee, RJ; Lomax, P; McCabe, RT; Olsen, RW; Wamsley, JK | 1 |
| Jackson, JA; Paul, SM; Schwartz, RD; Skolnick, P; Weigert, D | 1 |
| Little, HJ; Nutt, DJ; Taylor, SC | 1 |
| Dierssen, MM; Flórez, J; Hurlé, MA | 1 |
| Chweh, AY; Swinyard, EA; Wolf, HH | 1 |
| Majewska, MD; Mienville, JM; Vicini, S | 1 |
| Koga, K; Miura, I | 1 |
| Haberly, LB; Tseng, GF | 1 |
| Akaike, N; Maruyama, T; Tokutomi, N | 1 |
| Liljequist, S; Tabakoff, B | 1 |
| Girard, CL; Matte, JJ; Seoane, JR | 1 |
| Ramanjaneyulu, R; Ticku, MK | 1 |
| Kerr, DI; Ong, J | 1 |
| Collingridge, GL; Gage, PW; Robertson, B | 1 |
| Nicoll, RA; Wojtowicz, JM | 1 |
| Macdonald, RL; Schulz, DW | 1 |
| Davis, WC; Ticku, MK | 1 |
| Leeb-Lundberg, LM; Olsen, RW | 1 |
| Ashton, D | 1 |
| DiMicco, JA; Gillis, RA; Hamosh, P; Norman, WP; Segal, SA; Williford, DJ; Yamada, KA | 1 |
| Brunello, N; Cheney, DL | 1 |
| Gillis, RA; Hamosh, P; Moerschbaecher, JM; Yamada, KA | 1 |
| Alger, BE; Nicoll, RA | 2 |
| Macdonald, RL; McLean, MJ | 1 |
| Gormley, JM; Holtman, JR; Richter, JA; Simon, JR | 1 |
| Desarmenien, M; Feltz, P; Headley, PM; Santangelo, F | 1 |
| Burnham, WM; Kalichman, MW; Livingston, KE | 1 |
| Bormann, J; Feigenspan, A | 1 |
| Nabeshima, A; Saito, T; Takahata, N; Toki, S | 1 |
| Bormann, J; Feigenspan, A; Wässle, H | 1 |
| Kelder, D; Ross, SB | 1 |
| Ma, JY; Narahashi, T | 1 |
| Gore, JC; Petroff, OA; Prichard, JW; Zhong, J | 1 |
| Fukuda, H; Ito, Y; Segawa, K | 1 |
| Ferguson, AV; Loucks, C | 1 |
| Garau, F; Harris, RA; Sanna, E | 1 |
| Griffith, WH; Murchison, DA | 1 |
| Bähring, R; Grantyn, R; Martelli, EA; Standhardt, H | 1 |
| Belelli, D; Chen, R; Lambert, JJ; Lan, NC; Peters, JA; Reyes, A | 1 |
| Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Santoro, G | 1 |
| Lukasiewicz, PD; Maple, BR; Werblin, FS | 1 |
| Brown, J; Butterworth, AR; Little, HJ; Rabbani, M | 1 |
| Aguayo, LG; Alarcón, JM | 1 |
| Smart, TG; Xie, X | 1 |
| Misawa, M; Motegi, H; Suzuki, T | 1 |
| Dowling, JE; Qian, H | 1 |
| Krůsek, J; Vanĕcek, J; Zemková, H | 1 |
| Chang, YF; Gao, XM | 1 |
| Burt, D; Cestari, IN; Li, L; Uchida, I; Yang, J | 1 |
| Akaike, N; Harata, N; Shimura, M; Tamai, M | 1 |
| Fiszer de Plazas, S; Mitridate de Novara, A; Viapiano, MS | 1 |
| Harris, CL; Quinn, MR | 1 |
| Cestari, IN; Uchida, I; Yang, J | 1 |
| Bracamontes, J; Steinbach, JH; Ueno, S; Weiss, DS; Zorumski, C | 1 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Belachew, S; Coucke, P; Goffin, F; Lefebvre, PP; Malgrange, B; Moonen, G; Rigo, JM; Van de Water, TR; Xhauflaire, G | 1 |
| Simmonds, MA; Zhong, Y | 1 |
| Aimi, N; Leewanich, P; Matsumoto, K; Subhadhirasakul, S; Takayama, H; Tohda, M; Watanabe, H | 1 |
| Chang, X; Javors, MA; King, TS; Levinson, C; Ticku, MK | 1 |
| Greenfield, LJ; Macdonald, RL; Neelands, TR; Turner, RS; Zhang, J | 1 |
| Heal, DJ; Martin, KF; Phillips, I; Thompson, KS | 1 |
| Alvarez-Hernandez, X; Bueno, OF; Leidenheimer, NJ; Robinson, LC | 1 |
| Curtis, DR; Lacey, G | 1 |
| Guertin, PA; Hounsgaard, J | 1 |
| Hu, HZ; Li, ZW; Shao, M | 1 |
| Ben-Ari, Y; Rovira, C | 1 |
| Chau, C; Hales, TG; Kaufman, DL; Tian, J | 1 |
| Chen, CL; Chiu, TH; Yang, YR | 1 |
| Sapp, DW; Yeh, HH | 1 |
| Drinyaev, VA; Grichenko, AS; Kokoz, YM; Korystova, AF; Kruglyak, EB; Mosin, VA; Sterlina, TS; Tsyganova, VG; Victorov, AV; Zenchenko, KI | 1 |
| Birnir, B; Eghbali, M; Everitt, AB; Gage, PW | 1 |
| Findlay, GS; Harris, RA; Harrison, NL; Ueno, S | 2 |
| Kawamata, M; Namiki, A; Narimatsu, E; Tohdoh, Y | 1 |
| Lambert, JJ; Nicholls, DG; Rego, AC | 1 |
| Bozzini, CE; Fiszer de Plazas, S; Mitridate de Novara, AM; Viapiano, MS | 1 |
| Benson, JA; Darlison, MG; Forster, IC; Harvey, RJ | 1 |
| Baur, R; Dodd, RH; Furtmueller, R; Razet, R; Sieghart, W; Sigel, E | 1 |
| Baufreton, J; Bioulac, B; Dovero, S; Dufy, B; Garret, M; Taupignon, A | 1 |
| Aoyagi, Y; Ohta, A; Watanabe, Y; Yamada, K | 1 |
| Kullmann, DM; Semyanov, A | 1 |
| Menzikov, S; Menzikova, O | 1 |
| Birnir, B; Eghbali, M; Gage, PW | 1 |
| Dohi, S; Oshima, T | 1 |
| Chen, Z; Dillon, GH; Huang, RQ | 1 |
| Fregosi, RF; Iizuka, M; Luo, Z | 1 |
| Ariwodola, OJ; Weiner, JL | 1 |
| Forster, MJ; Gatch, MB; Selvig, M | 1 |
| Bäckström, T; Holmberg, E; Isaksson, M; Johansson, IM; Lindblad, C; Rahman, M; Taube, M; Wang, MD; Zhu, D | 1 |
| Mathers, DA; Puil, E; Wan, X | 1 |
| Archer, DP; Nguyen, KQ; Roth, SH; Samanani, N | 1 |
| Behan, M; Carey, HV; Hengen, KB; Johnson, SM; Jones, MV | 1 |
| Behan, M; Gomez, TM; Hengen, KB; Johnson, SM; Stang, KM | 1 |
| Egashira, N; Fujiwara, M; Ishibashi, A; Iwasaki, K; Mishima, K; Nishimura, R; Nogami, A; Oishi, R; Takasaki, K; Uchida, N | 1 |
| Behan, M; Crader, SM; Hengen, KB; Johnson, SM; Mitchell, GS; Nelson, NR; Stang, KM; Watters, JJ | 1 |
| Grauer, M; Jabs, R; Passlick, S; Schäfer, C; Seifert, G; Steinhäuser, C | 1 |
| Cheong, JH; Gao, Q; Hong, E; Jang, DS; Jeon, SJ; Lee, HE; Park, HJ; Park, SJ; Ryu, JH; Shin, CY | 1 |
| Dong, Z; Han, H; He, W; Tan, T; Tu, M; Wang, W | 1 |
| Chesnoy-Marchais, D | 1 |
| Chai, X; Chen, S; Gao, X; Huang, L; Jiao, S; Li, J; Ma, X; Tu, P; Wuken, S | 1 |
163 other study(ies) available for bicuculline and pentobarbital
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Caudate stimulation and substantia nigra activity in the rat.
Topics: Action Potentials; Anesthesia; Animals; Bicuculline; Brain Mapping; Caudate Nucleus; Electric Stimulation; Male; Mesencephalon; Neurons; Neurotransmitter Agents; Pentobarbital; Rats; Reticular Formation; Strychnine; Substantia Nigra; Urethane | 1976 |
Perivascular pH and pial arterial diameter during bicuculline induced seizures in cats.
Topics: Acid-Base Equilibrium; Animals; Arteries; Bicuculline; Cats; Chloralose; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Male; Pentobarbital; Phentolamine; Pia Mater; Seizures; Vasodilation | 1979 |
Drug-induced rhythmical activity in the inferior olivary complex of the rat.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Dopamine; Fenclonine; Gallamine Triethiodide; gamma-Aminobutyric Acid; Glutamates; Glycine; Harmaline; Harmine; Male; Neurons; Norepinephrine; Olivary Nucleus; Pentobarbital; Rats; Serotonin; Strychnine; Tryptamines; Tubocurarine | 1976 |
Barbiturate reversal of amino acid antagonism produced by convulsant agents.
Topics: Aminobutyrates; Animals; Barbiturates; Bicuculline; Binding Sites; Brain Stem; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Isoquinolines; Neurons; Pentobarbital; Rats; Receptors, Neurotransmitter; Strychnine | 1976 |
Reversal of the action of amino acid antagonists by barbiturates and other hypnotic drugs.
Topics: Aminobutyrates; Animals; Benzodiazepines; Bicuculline; Central Nervous System; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Interactions; Flurazepam; GABA Antagonists; Hypnotics and Sedatives; Male; Pentobarbital; Rats; Secobarbital; Strychnine; Synaptic Transmission | 1978 |
Potentiation of the effects of GABA by pentobarbitone.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Autonomic; Ganglia, Spinal; Nipecotic Acids; Pentobarbital; Rats; Receptors, Neurotransmitter; Spinal Cord | 1979 |
Modification of GABA-mediated depolarization of the cat ganglion by pentobarbital and two benzodiazepines.
Topics: Animals; Benzodiazepines; Bicuculline; Cats; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; Pentobarbital; Picrotoxin | 1979 |
Gamma-Aminobutyric acid and primary afferent depolarization in feline spinal cord.
Topics: Animals; Bicuculline; Cats; Female; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neuromuscular Depolarizing Agents; Neurons, Afferent; Nipecotic Acids; Pentobarbital; Semicarbazides; Spinal Cord; Time Factors | 1979 |
Interaction of pentobarbitone and gamma-aminobutyric acid on mammalian sympathetic ganglion cells.
Topics: Aminobutyrates; Animals; Bicuculline; Drug Synergism; GABA Antagonists; Membrane Potentials; Neural Conduction; Neurons; Pentobarbital; Rats; Taurine | 1978 |
Effects of benzodiazepines and pentobarbitone on the gaba-ergic recurrent inhibition of hippocampal neurons.
Topics: Action Potentials; Aminobutyrates; Animals; Benzodiazepines; Bicuculline; Cats; Diazepam; Drug Synergism; Female; gamma-Aminobutyric Acid; Hippocampus; Male; Neural Inhibition; Neurons; Pentobarbital | 1978 |
Pentobarbital: action on frog motoneurons.
Topics: Animals; Anura; Aspartic Acid; Bicuculline; Cell Membrane Permeability; Depression, Chemical; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Motor Neurons; Pentobarbital; Picrotoxin | 1975 |
Desensitization of GABAB receptors and antagonism by CGP 35348, prevent bicuculline- and picrotoxin-induced antinociception.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Drug Tolerance; GABA-A Receptor Antagonists; Injections, Intraventricular; Male; Mice; Motor Activity; Organophosphorus Compounds; Pain Measurement; Pentobarbital; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Assembly of functional GABAA receptors in insect cells using baculovirus expression vectors.
Topics: Animals; Baculoviridae; Bicuculline; Cattle; Cell Line; Cloning, Molecular; Evoked Potentials; gamma-Aminobutyric Acid; Genetic Vectors; Macromolecular Substances; Moths; Pentobarbital; Receptors, GABA-A; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1992 |
Gamma-aminobutyric acid type A receptor blockade at the intermediate area of the ventral surface of the medulla counteracts the cardiorespiratory depression produced by intravenous midazolam.
Topics: Animals; Bicuculline; Cardiovascular System; Cats; GABA-A Receptor Antagonists; Medulla Oblongata; Midazolam; Morphine; Naloxone; Pentobarbital; Respiratory System | 1992 |
Involvement of central GABAA receptor complex in controlling the basal gastric secretory activity in pylorus-ligated rats.
Topics: Analysis of Variance; Anesthesia; Animals; Bicuculline; Diazepam; Gastric Acid; Male; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1992 |
Evoked CA3 field potentials corresponding to both EPSPs and IPSPs in hippocampal slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Dendrites; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Penicillins; Pentobarbital; Phenobarbital; Pyramidal Tracts; Quinoxalines; Receptors, GABA-A; Synapses | 1992 |
GABA- and glutamate-activated currents in glial cells of the mouse corpus callosum slice.
Topics: Action Potentials; Animals; Bicuculline; Chloride Channels; Corpus Callosum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channel Gating; Kainic Acid; Membrane Proteins; Mice; Muscimol; Oligodendroglia; Pentobarbital; Potassium Channels; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Stem Cells | 1992 |
Chloride current induced by alcohols in rat dorsal root ganglion neurons.
Topics: Alcohols; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chlordiazepoxide; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Picrotoxin; Rats; Structure-Activity Relationship | 1992 |
Does glycine antagonism underlie the excitatory effects of methohexitone and propofol?
Topics: Anesthesia, General; Animals; Bicuculline; Central Nervous System; Electroencephalography; Ethanol; Glycine; Male; Methohexital; Mice; Mice, Inbred Strains; Pentobarbital; Propofol; Seizures; Strychnine | 1992 |
The effects of pentobarbital and benzodiazepines on GABA-responses in the periphery and spinal cord in vitro.
Topics: Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Male; Pentobarbital; Peripheral Nerves; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Synapses; Vagus Nerve | 1991 |
Effects of anxiolytic drugs on escape behavior induced by dorsal central gray stimulation in rats.
Topics: Animals; Anti-Anxiety Agents; Arousal; Avoidance Learning; Bicuculline; Brain Mapping; Bromazepam; Chlordiazepoxide; Diazepam; Electric Stimulation; Escape Reaction; GABA Antagonists; Male; Meprobamate; Pentobarbital; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains; Sensory Thresholds | 1991 |
Inhibitory transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Baclofen; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Pentobarbital; Potassium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
Effects of glycine and GABA on isolated bipolar cells of the mouse retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channels; Mice; Neurons; Pentobarbital; Picrotoxin; Potassium; Retina; Sodium; Strychnine | 1990 |
Expression of mammalian gamma-aminobutyric acid receptors with distinct pharmacology in Xenopus oocytes.
Topics: Animals; Baclofen; Bicuculline; Cattle; Cerebral Cortex; Electric Conductivity; gamma-Aminobutyric Acid; Gene Expression; Membrane Potentials; Oocytes; Pentobarbital; Picrotoxin; Poly A; Rats; Receptors, GABA-A; Retina; RNA; RNA, Messenger; Transfection; Xenopus | 1991 |
Correlation between gamma-aminobutyric acidA receptor ligand-induced changes in t-butylbicyclophosphoro[35S]thionate binding and 36Cl- uptake in rat cerebrocortical membranes.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Chloride Channels; Chlorides; Desoxycorticosterone; Diazepam; Ethanol; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Membrane Proteins; Pentobarbital; Pregnanolone; Rats; Receptors, GABA-A; Synaptosomes | 1991 |
Halothane enhances tonic neuronal inhibition by elevating intracellular calcium.
Topics: Animals; Bicuculline; Calcium; Dantrolene; Egtazic Acid; Evoked Potentials; gamma-Aminobutyric Acid; Halothane; Hippocampus; In Vitro Techniques; Male; Neurons; Pentobarbital; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses | 1991 |
Characteristics of midbrain control of spinal nociceptive neurons and nonsomatosensory parameters in the pentobarbital-anesthetized rat.
Topics: Anesthesia; Animals; Bicuculline; Blood Pressure; Electric Stimulation; Evoked Potentials; Glutamates; Hot Temperature; Male; Mesencephalon; Microinjections; Muscles; Neurons; Nociceptors; Pentobarbital; Rats; Rats, Inbred Strains; Somatosensory Cortex; Spinal Cord | 1991 |
gamma-Aminobutyric acid-induced response in acutely isolated nucleus solitarii neurons of the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Medulla Oblongata; Membrane Potentials; Muscimol; Neurons; Penicillin G; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1991 |
Effects of enoxacin and its combination with 4-biphenylacetate, an active metabolite of fenbufen, on population spikes in rat hippocampal slices.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Bicuculline; Clorazepate Dipotassium; Drug Interactions; Electric Stimulation; Enoxacin; Hippocampus; In Vitro Techniques; Male; Muscimol; Pentobarbital; Phenylacetates; Phenylbutyrates; Rats; Rats, Inbred Strains | 1991 |
Interactions of GABAA antagonists with deltamethrin, diazepam, pentobarbital, and SKF100330A in the rat dentate gyrus.
Topics: Action Potentials; Animals; Anticonvulsants; Bicuculline; Diazepam; Drug Interactions; Female; GABA Antagonists; Hippocampus; Insecticides; Male; Membrane Potentials; Nicotinic Acids; Nitriles; Pentobarbital; Picrotoxin; Pyrethrins; Rats; Rats, Inbred Strains | 1991 |
[Taurine-activated currents in isolated neurons of the rat cerebellum].
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Membrane Potentials; Oxazepam; Pentobarbital; Purkinje Cells; Rats; Strychnine; Taurine | 1990 |
Comparison of contractile responses of the guinea pig ileum longitudinal muscle to ethanol and GABAA agonists.
Topics: Animals; Atropine; Bicuculline; Chlorides; Ethanol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Taurine; Tetrodotoxin | 1990 |
Characterization of GABAergic seizure regulation in the midline thalamus.
Topics: Animals; Baclofen; Bicuculline; Electroencephalography; Epilepsy; Female; Flurazepam; gamma-Aminobutyric Acid; Pentobarbital; Pentylenetetrazole; Piperidines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thalamic Nuclei | 1990 |
Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones.
Topics: Animals; Baclofen; Bicuculline; Crotonates; Diazepam; Dibenzazepines; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Neurons; Pentobarbital; Picrotoxin; Receptors, GABA-A; Snails | 1990 |
Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes.
Topics: Animals; Bicuculline; Biological Transport; Brain; Cell-Free System; Chlorides; Ethanol; In Vitro Techniques; Ion Channels; Muscimol; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Synaptosomes | 1986 |
Characterization of spontaneous and evoked inhibitory postsynaptic potentials in rat supraoptic neurosecretory neurons in vitro.
Topics: Animals; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Male; Membrane Potentials; Neural Inhibition; Neurons; Neurosecretory Systems; Pentobarbital; Rats; Rats, Inbred Strains; Strychnine; Supraoptic Nucleus; Synapses | 1986 |
[GABA-activated conductance of mammalian cerebellar neurons].
Topics: Animals; Bicuculline; Chlorides; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Pentobarbital; Potassium; Purkinje Cells; Rats; Receptors, GABA-A | 1986 |
Spontaneous EEG spikes in the normal hippocampus. V. Effects of ether, urethane, pentobarbital, atropine, diazepam and bicuculline.
Topics: Anesthetics; Animals; Atropine; Behavior, Animal; Bicuculline; Diazepam; Electroencephalography; Ether; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Pentobarbital; Rats; Reference Values; Seizures; Urethane | 1988 |
Aging reduces the GABA-dependent 36Cl- flux in rat brain membrane vesicles.
Topics: Aging; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebellum; Cerebral Cortex; Chlorides; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Genotype-dependent effects of GABAergic agents on sedative properties of ethanol.
Topics: Animals; Bicuculline; Ethanol; gamma-Aminobutyric Acid; Genetics, Behavioral; Genotype; Hypnotics and Sedatives; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Muscimol; Pentobarbital; Picrotoxin; Species Specificity | 1989 |
Effects of GABA antagonists on the pentobarbital-induced depression of respiration and cough in rats.
Topics: Animals; Bicuculline; Cough; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reflex; Respiration; Strychnine | 1989 |
Differential effects of iodide and chloride on allosteric interactions of the GABAA receptor.
Topics: Allosteric Regulation; Animals; Anions; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Chlorides; Diazepam; gamma-Aminobutyric Acid; Iodides; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
RO15-4513 but not FG-7142 reverses anticonvulsant effects of ethanol against bicuculline- and picrotoxin-induced convulsions in rats.
Topics: Affinity Labels; Animals; Appetite Depressants; Azides; Benzodiazepines; Bicuculline; Carbolines; Ethanol; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1989 |
Pharmacology of a novel effect of gamma-aminobutyric acid on the frog optic tectum in vitro.
Topics: Animals; Bicuculline; Chlorides; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Midazolam; Muscimol; Pentobarbital; Rana temporaria; Superior Colliculi | 1989 |
Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice.
Topics: Animals; Anticonvulsants; Bicuculline; Body Temperature; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; Infusions, Intravenous; Male; Mice; Motor Activity; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1988 |
Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors.
Topics: Animals; Anticonvulsants; Atropine; beta-Alanine; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Indomethacin; Male; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stomach Ulcer; Taurine | 1988 |
Effects of drugs on the electrical activity of the red nucleus in the rabbit. Activation of benzodiazepine and barbiturate receptors.
Topics: Animals; Bicuculline; Carbolines; Diazepam; Drug Interactions; Electroencephalography; Flumazenil; Muscle Relaxation; Pentobarbital; Pyridazines; Rabbits; Receptors, GABA-A; Receptors, Neurotransmitter; Red Nucleus | 1988 |
Interactions of pentobarbital and phenobarbital with GABAergic drugs against chemoconvulsants in rats.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Convulsants; Diazepam; Drug Interactions; Isoxazoles; Male; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Strychnine | 1988 |
Biophysical and pharmacological properties of cloned GABAA receptor subunits expressed in Xenopus oocytes.
Topics: Animals; Bicuculline; Female; Membrane Potentials; Oocytes; Pentobarbital; Receptors, GABA-A; Xenopus laevis | 1988 |
Excitatory and differential disinhibitory actions of acetylcholine in the lateral geniculate nucleus of the cat.
Topics: Acetylcholine; Action Potentials; Animals; Bicuculline; Cats; Cold Temperature; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamates; Glutamic Acid; Neural Inhibition; Neurons; Pentobarbital; Retinal Ganglion Cells; Time Factors; Visual Cortex | 1986 |
Benzodiazepine, beta-carboline, and barbiturate actions on GABA responses.
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Bicuculline; Carbolines; Cells, Cultured; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Membrane Potentials; Mice; Neurons; Nitrazepam; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, GABA-A; Spinal Cord | 1986 |
Effects of microiontophoretic pentobarbitone on conditioned inhibitions mediated by GABA-A receptors in the cuneate nucleus of the rat in-vivo.
Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials; Iontophoresis; Male; Medulla Oblongata; Neural Inhibition; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Pharmacology of GABA receptors on skeletal muscle fibres of the locust (Schistocerca gregaria).
Topics: Amino Acids; Animals; Bicuculline; Dicarboxylic Acids; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Grasshoppers; Hydrogen-Ion Concentration; Muscles; Pentobarbital; Receptors, GABA-A | 1987 |
Contributions of inhibitory mechanisms to the shift responses of X and Y cells in the cat lateral geniculate nucleus.
Topics: Acetylcholine; Action Potentials; Anesthesia, General; Animals; Bicuculline; Cats; Geniculate Bodies; Glutamates; Glutamic Acid; Neural Inhibition; Neurons; Pentobarbital; Time Factors | 1987 |
Pharmacologically induced changes in the latency of digastric reflexes in 1-7 day old rabbits.
Topics: Animals; Animals, Newborn; Bicuculline; Decerebrate State; Diazepam; Electromyography; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rabbits; Reflex; Stomach; Strychnine; Synaptic Transmission | 1988 |
Regulation of [3H]GABA release from strips of guinea pig urinary bladder.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Bicuculline; Clonazepam; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Pentobarbital; Phenylephrine; Pirenzepine; Potassium; Prazosin; Tritium; Urinary Bladder; Yohimbine | 1988 |
Avermectin B1a modulation of gamma-aminobutyric acid/benzodiazepine receptor binding in mammalian brain.
Topics: Animals; Bicuculline; Brain; Cattle; Cell Membrane; Cerebral Cortex; Etazolate; gamma-Aminobutyric Acid; Isonicotinic Acids; Ivermectin; Lactones; Muscimol; Pentobarbital; Rats; Receptors, GABA-A | 1985 |
Involvement of a GABAergic mechanism in the anticonvulsant effect of pentobarbital against maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Drug Interactions; Electroshock; Ethanol; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Sleep | 1985 |
gamma-Aminobutyric acid partly mediates the pentobarbitone depression of synaptic excitation in the guinea-pig olfactory cortex in vitro.
Topics: Animals; Bicuculline; Drug Interactions; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Limbic System; Male; Membrane Potentials; Olfactory Pathways; Pentobarbital; Picrotoxin; Synapses; Synaptic Transmission | 1985 |
Benzodiazepine/gamma-aminobutyric acid receptor deficit in the midbrain of the seizure-susceptible gerbil.
Topics: Animals; Bicuculline; Diazepam; Disease Models, Animal; Flunitrazepam; Gerbillinae; Mesencephalon; Muscimol; Pentobarbital; Receptors, GABA-A; Seizures | 1985 |
Characterization of barbiturate-stimulated chloride efflux from rat brain synaptoneurosomes.
Topics: Amobarbital; Animals; Barbiturates; Bicuculline; Brain; Cell Membrane Permeability; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Hexobarbital; Male; Mephobarbital; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Rubidium; Secobarbital; Synapses | 1985 |
The effects of drugs acting at the GABAA-receptor/ionophore after chemical kindling with the benzodiazepine receptor ligand FG 7142.
Topics: Animals; Bicuculline; Body Temperature; Carbolines; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1986 |
Mechanism of the respiratory action of pentobarbital at the medullary and pontine levels.
Topics: Animals; Bicuculline; Cats; Female; Hemodynamics; Male; Medulla Oblongata; Pentobarbital; Pons; Receptors, GABA-A; Respiration; Time Factors | 1986 |
Comparison of anticonvulsant effect of pentobarbital and phenobarbital against seizures induced by maximal electroshock and picrotoxin in rats.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Anticonvulsants; Bicuculline; Electroshock; Male; Muscimol; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1986 |
Hypnotic action of pentobarbital in mice: a possible mechanism.
Topics: Animals; Baclofen; Bicuculline; Isoxazoles; Male; Mice; Oxazoles; Pentobarbital; Receptors, GABA-A; Reflex; Sleep | 1987 |
Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Pentobarbital; Pregnenolone; Rats; Steroids | 1988 |
A measurement of cerebral glucose uptake rate by 31P MRS.
Topics: Analgesia; Animals; Bicuculline; Blood Pressure; Brain; Deoxy Sugars; Deoxyglucose; Epilepsy; Glucose-6-Phosphate; Glucosephosphates; Heart Rate; Kinetics; Magnetic Resonance Spectroscopy; Male; Nitrous Oxide; Pentobarbital; Rats; Rats, Inbred WKY | 1988 |
Characterization of synaptically mediated fast and slow inhibitory processes in piriform cortex in an in vitro slice preparation.
Topics: Animals; Bicuculline; Cerebral Cortex; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Pentobarbital; Picrotoxin; Potassium; Rats; Reaction Time; Synapses | 1988 |
Possible involvement of the central GABAergic system in pentobarbital-stimulated gastric acid secretion in the perfused rat stomach preparation.
Topics: 3-Mercaptopropionic Acid; Anesthesia; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Male; Pentobarbital; Pentylenetetrazole; Perfusion; Picrotoxin; Rats; Rats, Inbred Strains; Urethane | 1988 |
Kinetic properties of the pentobarbitone-gated chloride current in frog sensory neurones.
Topics: Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Neurons, Afferent; Pentobarbital; Picrotoxin; Rana catesbeiana | 1987 |
Bicuculline-pentobarbital interactions on [35S]TBPS binding in various brain areas.
Topics: Animals; Bicuculline; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Dose-Response Relationship, Drug; Drug Interactions; Kinetics; Male; Mice; Mice, Inbred C57BL; Pentobarbital; Tissue Distribution | 1986 |
Studies of the role of gamma-aminobutyric acid in the hypothalamic control of feed intake in sheep.
Topics: Animals; Bicuculline; Brain; Eating; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Pentobarbital; Picrotoxin; Sheep | 1985 |
Differential interactions of GABA agonists, depressant and convulsant drugs with [35S]-t-butylbicyclophosphorothionate binding sites in cortex and cerebellum.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Central Nervous System Depressants; Cerebellum; Cerebral Cortex; Convulsants; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Mitochondria; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission; Thiocyanates | 1984 |
Potentiation of GABAA-receptor-mediated responses by barbiturates in the guinea-pig ileum.
Topics: Animals; Barbiturates; Bicuculline; Drug Interactions; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes | 1984 |
Inhibitory post-synaptic currents in rat hippocampal CA1 neurones.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Time Factors | 1984 |
The effects of pentobarbital and related compounds on frog motoneurons.
Topics: Amino Acids; Animals; Anura; Bicuculline; Chloralose; Chlordiazepoxide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Motor Neurons; Muscimol; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Spinal Cord; Strychnine; Synaptic Transmission | 1980 |
Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions.
Topics: Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Ion Channels; Mice; Neural Inhibition; Neurons; Pentobarbital; Phenobarbital; Spinal Cord | 1981 |
Pentobarbital enhances [3H]diazepam binding to soluble receptors at the benzodiazepine--GABA-receptor-ionophore complex.
Topics: Animals; Bicuculline; Diazepam; Dose-Response Relationship, Drug; In Vitro Techniques; Ionophores; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Tritium | 1981 |
Heterogeneity of benzodiazepine receptor interactions with gamma-aminobutyric acid and barbiturate receptor sites.
Topics: Animals; Bicuculline; Binding Sites; Brain; Diazepam; gamma-Aminobutyric Acid; Kinetics; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Tissue Distribution | 1983 |
Diazepam, pentobarbital and D-etomidate produced increases in bicuculline seizure threshold; selective antagonism by RO15-1788, picrotoxin and (+/-)-DMBB.
Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Diazepam; Etomidate; Flumazenil; Imidazoles; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1983 |
Central gamma-aminobutyric acid involvement in blood pressure control.
Topics: Animals; Bicuculline; Blood Pressure; Brain; Cats; Disease Models, Animal; gamma-Aminobutyric Acid; Guinea Pigs; Hypertension; Medulla Oblongata; Pentobarbital; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Respiration | 1984 |
The septal-hippocampal cholinergic pathway: role in antagonism of pentobarbital anesthesia and regulation by various afferents.
Topics: Acetylcholine; Anesthesia; Animals; Bicuculline; Brain; Hippocampus; Kainic Acid; Male; Neural Pathways; Neurons, Afferent; Parasympathetic Nervous System; Pentobarbital; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1981 |
Pentobarbital causes cardiorespiratory depression by interacting with a GABAergic system at the ventral surface of the medulla.
Topics: Animals; Bicuculline; Blood Pressure; Cats; gamma-Aminobutyric Acid; Heart Rate; Medulla Oblongata; Pentobarbital; Respiration; Tidal Volume | 1983 |
Pharmacological evidence for two kinds of GABA receptor on rat hippocampal pyramidal cells studied in vitro.
Topics: Animals; Bicuculline; Dendrites; Diazepam; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Membrane Potentials; Penicillins; Pentobarbital; Pyramidal Tracts; Rats; Receptors, Drug | 1982 |
Cellular bases of barbiturate and phenytoin anticonvulsant drug action.
Topics: Animals; Barbiturates; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Neurons; Pentobarbital; Phenobarbital; Phenytoin; Synapses | 1982 |
High-affinity choline uptake in the hippocampus: its relationship to the physiological state produced by administration of barbiturates and other treatments.
Topics: Animals; Barbiturates; Bicuculline; Choline; Convulsants; Hippocampus; Kinetics; Male; Mice; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Septum Pellucidum; Synaptosomes | 1982 |
Direct action of pentobarbitone in potentiating the responses to GABA of rat dorsal root ganglion neurones in vitro.
Topics: Action Potentials; Animals; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Neurons; Pentobarbital; Picrotoxin; Rats | 1981 |
Pharmacological investigation of gamma aminobutyric acid (GABA) and the development of amygdala-kindled seizures in the rat.
Topics: 3-Mercaptopropionic Acid; 4-Aminobutyrate Transaminase; Aminocaproates; Amygdala; Animals; Bicuculline; gamma-Aminobutyric Acid; Imidazoles; Kindling, Neurologic; Male; Pentobarbital; Picrotoxin; Rats; Seizures; Vigabatrin | 1981 |
Spontaneous inhibitory post-synaptic potentials in hippocampus: mechanism for tonic inhibition.
Topics: Animals; Bicuculline; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Pentobarbital; Rats; Synapses; Tetrodotoxin | 1980 |
Differential pharmacology of GABAA and GABAC receptors on rat retinal bipolar cells.
Topics: Animals; Bicuculline; Binding Sites; Cells, Cultured; Chickens; Chloride Channels; Dose-Response Relationship, Drug; Flunitrazepam; GABA Antagonists; GABA-A Receptor Antagonists; Hexachlorocyclohexane; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Retina; Sesterterpenes; Signal Transduction | 1994 |
[Changes in GABAA/benzodiazepine receptor complex function in the pentobarbital-dependent rat. II: Strain differences between Lewis and Wistar-Kyoto rats].
Topics: Animals; Bicuculline; Brain; Chlorine; Ethanol; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Lew; Rats, Inbred WKY; Receptors, GABA-A; Substance-Related Disorders | 1995 |
Pharmacology of GABA receptor Cl- channels in rat retinal bipolar cells.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Photoreceptor Cells; Picrotoxin; Pregnanediones; Rats; Receptors, GABA-A; Sesterterpenes; Strychnine | 1993 |
Counteraction of the rapid tolerance to 8-OH-DPAT-induced corticosterone secretion in rats by activation of the GABAA receptor-chloride channel complex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzodiazepines; Bicuculline; Chloride Channels; Chlormethiazole; Corticosterone; Drug Tolerance; Ion Channels; Male; Membrane Proteins; Muscimol; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1993 |
Enhancement of gamma-aminobutyric acid-activated chloride channel currents by lanthanides in rat dorsal root ganglion neurons.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chlordiazepoxide; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Metals, Rare Earth; Neurons; Penicillins; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Terbium; Zinc | 1993 |
Barbiturate-reversible reduction of water diffusion coefficient in flurothyl-induced status epilepticus in rats.
Topics: Animals; Bicuculline; Body Water; Brain; Diffusion; Dose-Response Relationship, Drug; Electroencephalography; Female; Flurothyl; Halothane; Magnetic Resonance Imaging; Morphine; Nitrous Oxide; Pentobarbital; Rats; Status Epilepticus; Time Factors | 1995 |
Functional diversity of GABAA receptor ligand-gated chloride channels in rat synaptoneurosomes.
Topics: Animals; Bicuculline; Brain; Chloride Channels; Chlorides; Desoxycorticosterone; Ion Channel Gating; Ligands; Male; Muscimol; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Synaptosomes; Tissue Distribution | 1995 |
Cardiovascular and single-unit responses to subfornical organ stimulation are abolished by pentobarbital anesthesia.
Topics: Angiotensin II; Animals; Bicuculline; Blood Pressure; Electric Stimulation; GABA Antagonists; Male; Neural Pathways; Pentobarbital; Pituitary Gland, Posterior; Rats; Subfornical Organ; Urethane | 1994 |
Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Propofol; Receptors, GABA-A; Strychnine; Xenopus laevis | 1995 |
Enhancement of GABA-activated membrane currents in aged Fischer 344 rat basal forebrain neurons.
Topics: Action Potentials; Aging; Animals; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Ion Channel Gating; Lanthanum; Midazolam; Pentobarbital; Rats; Rats, Inbred F344; Receptors, GABA-A; Septum Pellucidum; Tetrodotoxin; Zinc | 1995 |
GABA-activated chloride currents of postnatal mouse retinal ganglion cells are blocked by acetylcholine and acetylcarnitine: how specific are ion channels in immature neurons?
Topics: Acetylcarnitine; Acetylcholine; Action Potentials; Animals; Bicuculline; Chloride Channels; Clonazepam; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Potassium Chloride; Pregnanolone; Quinoxalines; Retina; Retinal Ganglion Cells; Strychnine; Substrate Specificity; Tetrodotoxin; Zinc | 1994 |
Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cloning, Molecular; Convulsants; DNA Primers; DNA, Complementary; Drosophila melanogaster; Female; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Molecular Sequence Data; Muscimol; Oocytes; Pentobarbital; Picrotoxin; Polymerase Chain Reaction; Receptors, GABA; Receptors, GABA-A; Transcription, Genetic; Xenopus laevis | 1994 |
Effects of propofol, pentobarbital and alphaxalone on t-[35S]butylbicyclophosphorothionate binding in rat cerebral cortex.
Topics: Anesthetics; Animals; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Male; Membranes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes | 1994 |
A novel GABA receptor on bipolar cell terminals in the tiger salamander retina.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela | 1994 |
Dihydropyridine-sensitive calcium channels and barbiturate tolerance and withdrawal.
Topics: Anesthesia, General; Animals; Ataxia; Barbiturates; Bicuculline; Calcium Channels; Carbolines; Dihydropyridines; Drug Tolerance; Male; Mice; Mice, Inbred Strains; Nitrendipine; Pentobarbital; Seizures; Substance Withdrawal Syndrome | 1994 |
Modulation of the developing rat sympathetic GABAA receptor by Zn++, benzodiazepines, barbiturates and ethanol.
Topics: Aging; Animals; Barbiturates; Benzodiazepines; Bicuculline; Diazepam; Ethanol; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Neurons; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sensitivity and Specificity; Superior Cervical Ganglion; Zinc | 1993 |
Properties of GABA-mediated synaptic potentials induced by zinc in adult rat hippocampal pyramidal neurones.
Topics: Action Potentials; Animals; Bicuculline; Culture Techniques; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Pentobarbital; Picrotoxin; Rats; Synapses; Synaptic Transmission; Zinc | 1993 |
Attenuation of anticonvulsant effects of diazepam after chronic treatment with bicuculline.
Topics: Animals; Anticonvulsants; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, GABA; Sleep | 1993 |
Novel GABA responses from rod-driven retinal horizontal cells.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscimol; Pentobarbital; Perches; Photoreceptor Cells; Receptors, GABA; Retina | 1993 |
Electrophysiological characterization of GABAA receptors in anterior pituitary cells of newborn rats.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Diazepam; Drug Tolerance; Electric Conductivity; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pituitary Gland, Anterior; Rats; Receptors, GABA; Zinc | 1995 |
L-lysine is a barbiturate-like anticonvulsant and modulator of the benzodiazepine receptor.
Topics: Animals; Anions; Anticonvulsants; Barbiturates; Bicuculline; Brain Chemistry; Cattle; Central Nervous System Depressants; Diazepam; gamma-Aminobutyric Acid; Lysine; Male; Mice; Pentobarbital; Picrotoxin; Radioligand Assay; Receptors, GABA-A; Stimulation, Chemical | 1995 |
The agonistic action of pentobarbital on GABAA beta-subunit homomeric receptors.
Topics: Animals; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; Mice; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Xenopus | 1996 |
Allosteric modulation of GABAA receptors in acutely dissociated neurons of the suprachiasmatic nucleus.
Topics: Allosteric Regulation; Animals; Bicuculline; Chlorides; Diazepam; Electric Conductivity; Female; GABA Antagonists; GABA-A Receptor Agonists; Intracellular Membranes; Male; Neurons; Pentobarbital; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Suprachiasmatic Nucleus | 1996 |
Pentobarbital modulatory effect on GABA binding sites in developing chick optic lobe.
Topics: Animals; Bicuculline; Brain; Chick Embryo; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Pentobarbital; Picrotoxin; Sesterterpenes; Synaptic Membranes | 1995 |
Taurine allosterically inhibits binding of [35S]-t-butylbicyclophosphorothionate (TBPS) to rat brain synaptic membranes.
Topics: Allosteric Regulation; Animals; Bicuculline; Binding Sites; Brain Stem; Bridged Bicyclo Compounds, Heterocyclic; Clonazepam; Convulsants; gamma-Aminobutyric Acid; Male; Pentobarbital; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes; Synaptic Membranes; Taurine | 1995 |
The differential antagonism by bicuculline and SR95531 of pentobarbitone-induced currents in cultured hippocampal neurons.
Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Bicuculline; Binding Sites; Cells, Cultured; Chloride Channels; Chlorides; Etomidate; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Models, Molecular; Neurons; Pentobarbital; Pyridazines; Rats; Receptors, GABA-A | 1996 |
Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Bicuculline; Binding Sites; Binding, Competitive; Cell Line; Coturnix; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Transport; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Pentobarbital; Point Mutation; Pregnanediones; Pregnanolone; Protein Binding; Pyridazines; Receptors, GABA-A; Structure-Activity Relationship | 1997 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Diazepam-insensitive GABAA receptors on postnatal spiral ganglion neurones in culture.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Carbolines; Cells, Cultured; Convulsants; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spiral Ganglion; Zinc | 1997 |
Interactions between loreclezole, chlormethiazole and pentobarbitone at GABA(A) receptors: functional and binding studies.
Topics: Animals; Anticonvulsants; Bicuculline; Chlormethiazole; Flunitrazepam; In Vitro Techniques; Male; Medulla Oblongata; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Triazoles | 1997 |
Inhibitory effects of corymine, an alkaloidal component from the leaves of Hunteria zeylanica, on glycine receptors expressed in Xenopus oocytes.
Topics: Alkaloids; Animals; Bicuculline; Brain; Convulsants; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Midazolam; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Plant Leaves; Rats; Receptors, GABA-A; Receptors, Glycine; Trees; Xenopus | 1997 |
Characterization of chloride efflux from GT1-7 neurons: lack of effect of ethanol on GABAA response.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicuculline; Bumetanide; Cells, Cultured; Central Nervous System Stimulants; Chlorides; Diuretics; Ethanol; GABA Agonists; GABA Antagonists; GABA Modulators; Mice; Muscimol; Neurons; Pentobarbital; Receptors, GABA-A; Temperature | 1998 |
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells.
Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem | 1998 |
GABA-evoked depolarisations in the rat cortical wedge: involvement of GABAA receptors and HCO3- ions.
Topics: Animals; Bicarbonates; Bicuculline; Cerebral Cortex; Chlordiazepoxide; Electrophysiology; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Ions; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1998 |
Functional characterization and visualization of a GABAA receptor-GFP chimera expressed in Xenopus oocytes.
Topics: Anesthetics; Animals; Bicuculline; Cell Membrane; Desoxycorticosterone; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indicators and Reagents; Ion Channel Gating; Luminescent Proteins; Membrane Potentials; Microscopy, Confocal; Midazolam; Oocytes; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Fusion Proteins; Xenopus laevis | 1998 |
Prolonged GABA(B) receptor-mediated synaptic inhibition in the cat spinal cord: an in vivo study.
Topics: Animals; Baclofen; Bicuculline; Cats; Electric Stimulation; Electrophysiology; Female; GABA Agonists; GABA Antagonists; GABA Modulators; Male; Membrane Potentials; Motor Neurons; Neural Inhibition; Pentobarbital; Phosphinic Acids; Propanolamines; Receptors, GABA-A; Receptors, GABA-B; Reflex; Spinal Cord; Synapses | 1998 |
Non-volatile general anaesthetics reduce spinal activity by suppressing plateau potentials.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Bicuculline; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Excitatory Postsynaptic Potentials; GABA Antagonists; Interneurons; Motor Neurons; Pentobarbital; Propofol; Receptors, GABA-A; Serotonin; Spinal Cord; Tetrodotoxin; Thiopental; Turtles | 1999 |
Enhancement of GABA-activated current by muscarine in rat dorsal root ganglion neurons.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Carbachol; Carbolines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Modulators; Gallamine Triethiodide; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channel Gating; Ion Channels; Male; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nerve Tissue Proteins; Nicotinic Antagonists; Patch-Clamp Techniques; Pentobarbital; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Muscarinic | 1999 |
Developmental study of miniature IPSCs of CA3 hippocampal cells: modulation by midazolam.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA Modulators; Hippocampus; Isonicotinic Acids; Male; Midazolam; Neural Inhibition; Neurons; Organ Culture Techniques; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Tetrodotoxin | 1999 |
GABA(A) receptors mediate inhibition of T cell responses.
Topics: Amidines; Animals; Autocrine Communication; Bicuculline; CD3 Complex; Cell Division; Enzyme Inhibitors; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hypersensitivity, Delayed; Immunosuppression Therapy; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred NOD; Muscimol; Pentobarbital; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; T-Lymphocytes; Vigabatrin | 1999 |
Activation of rat locus coeruleus neuron GABA(A) receptors by propofol and its potentiation by pentobarbital or alphaxalone.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Baclofen; Barium Compounds; Bicuculline; Chlorides; Diazepam; Drug Synergism; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ionophores; Locus Coeruleus; Male; Neurons; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds | 1999 |
Heterogeneity of GABA(A) receptor-mediated responses in the human IMR-32 neuroblastoma cell line.
Topics: Anticonvulsants; Bicuculline; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Humans; Neuroblastoma; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Protein Isoforms; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles; Tumor Cells, Cultured; Zinc | 2000 |
Selective cytostatic and neurotoxic effects of avermectins and activation of the GABAalpha receptors.
Topics: Animals; Bicuculline; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Ivermectin; Male; Neuroblastoma; Neurons; Neurotoxins; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Septal Nuclei; Tumor Cells, Cultured | 1999 |
Bicuculline, pentobarbital and diazepam modulate spontaneous GABA(A) channels in rat hippocampal neurons.
Topics: Animals; Bicuculline; Cells, Cultured; Diazepam; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Pentobarbital; Rats; Receptors, GABA-A | 2000 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors [corrected].
Topics: Allosteric Regulation; Amino Acid Substitution; Animals; Bicuculline; Cells, Cultured; Female; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Picrotoxin; Protein Structure, Tertiary; Receptors, GABA-A; Steroids; Xenopus laevis | 2000 |
The involvement of adenosine neuromodulation in pentobarbital-induced field excitatory postsynaptic potentials depression in rat hippocampal slices.
Topics: Adenosine; Aminophylline; Animals; Bicuculline; Depression, Chemical; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA Modulators; Hippocampus; In Vitro Techniques; Male; Neurotransmitter Agents; Pentobarbital; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission; Xanthines | 2000 |
Developmental profile of excitatory GABA(A) responses in cultured rat cerebellar granule cells.
Topics: Allosteric Regulation; Animals; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Differentiation; Cells, Cultured; Cerebellum; Chlorides; Cytosol; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Mitochondria; Nifedipine; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Steroids | 2001 |
Prolonged exposure to hypobaric hypoxia transiently reduces GABA(A) receptor number in mice cerebral cortex.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Cerebral Cortex; Desoxycorticosterone; GABA Antagonists; GABA Modulators; Hypoxia, Brain; Male; Mice; Pentobarbital; Receptors, GABA-A | 2001 |
Functional pharmacology of GABA(A) receptors containing the chicken brain gamma 4 subunit.
Topics: Animals; Bicuculline; Brain Chemistry; Chickens; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Oocytes; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Protein Subunits; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis; Zinc | 2001 |
Differential cross talk of ROD compounds with the benzodiazepine binding site.
Topics: Alkaloids; Allosteric Regulation; Animals; Benzodiazepines; Bicuculline; Binding Sites; Cells, Cultured; GABA Modulators; Humans; Pentobarbital; Rats; Receptor Cross-Talk; Receptors, GABA-A | 2001 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors.
Topics: Allosteric Regulation; Animals; Bicuculline; Electric Conductivity; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pregnanolone; Protein Isoforms; Receptors, GABA-A; Xenopus laevis | 2001 |
Activation of GABA(A) receptors in subthalamic neurons in vitro: properties of native receptors and inhibition mechanisms.
Topics: Animals; Bicarbonates; Bicuculline; Chlorides; Diazepam; Electrophysiology; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Organ Culture Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes; Subthalamic Nucleus | 2001 |
Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Convulsants; Diazepam; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Injections, Intraventricular; Male; Mice; Pentobarbital; Picrotoxin; Pyrazines; Seizures; Sleep; Time Factors; Valproic Acid | 2001 |
Relative picrotoxin insensitivity distinguishes ionotropic GABA receptor-mediated IPSCs in hippocampal interneurons.
Topics: Animals; Bicuculline; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Iontophoresis; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pyramidal Cells; Pyridines; Receptors, GABA; Receptors, GABA-A; Zolpidem | 2002 |
Interaction of pentobarbital with gabaergic drugs acting on the Cl(-)-ATPase activity of the plasma membranes from bream brain (Abramis brama L.).
Topics: Adenosine Triphosphatases; Animals; Anion Transport Proteins; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sea Bream | 2002 |
Conductance of GABAA channels activated by pentobarbitone in hippocampal neurons from newborn rats.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Diazepam; Electric Conductivity; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Ion Channel Gating; Neurons; Patch-Clamp Techniques; Pentobarbital; Rats; Receptors, GABA-A | 2003 |
Isoflurane facilitates hiccup-like reflex through gamma aminobutyric acid (GABA)A- and suppresses through GABAB-receptors in pentobarbital-anesthetized cats.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Bicuculline; Blood Pressure; Cats; Cisterna Magna; Electromyography; GABA Agonists; GABA Antagonists; GABA Modulators; Heart Rate; Hiccup; Hyperventilation; Injections; Injections, Intravenous; Isoflurane; Organophosphorus Compounds; Pentobarbital; Pharynx; Physical Stimulation; Receptors, GABA-A; Receptors, GABA-B; Respiration, Artificial | 2004 |
Molecular basis for modulation of recombinant alpha1beta2gamma2 GABAA receptors by protons.
Topics: Bicuculline; Binding Sites; Cell Line; Diethyl Pyrocarbonate; Electrophysiology; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Mutation; Patch-Clamp Techniques; Pentobarbital; Protons; Receptors, GABA-A; Recombinant Proteins; Zinc | 2004 |
GABAA receptors mediate postnatal depression of respiratory frequency by barbiturates.
Topics: Animals; Animals, Newborn; Bicuculline; Drug Interactions; Female; GABA Agents; Hypnotics and Sedatives; In Vitro Techniques; Muscimol; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Respiratory Center; Respiratory Insufficiency; Respiratory Mechanics; Spinal Cord; Spinal Nerve Roots | 2004 |
Ethanol potentiation of GABAergic synaptic transmission may be self-limiting: role of presynaptic GABA(B) receptors.
Topics: Animals; Autoreceptors; Baclofen; Bicuculline; Central Nervous System Depressants; Electric Stimulation; Electrophysiology; Ethanol; Flunitrazepam; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Male; Morpholines; Neural Inhibition; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission | 2004 |
GABAergic modulation of the discriminative stimulus effects of methamphetamine.
Topics: Animals; Bicuculline; Central Nervous System Stimulants; Chlordiazepoxide; Discrimination Learning; Discrimination, Psychological; Drug Interactions; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Methamphetamine; Pentobarbital; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2005 |
GABA-site antagonism and pentobarbital actions do not depend on the alpha-subunit type in the recombinant rat GABA receptor.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Female; GABA Antagonists; Oocytes; Patch-Clamp Techniques; Pentobarbital; Rats; Receptors, GABA-A; Recombinant Proteins; Xenopus | 2006 |
Barbiturate activation and modulation of GABA(A) receptors in neocortex.
Topics: Animals; Animals, Newborn; Barbiturates; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neocortex; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Thalamus | 2007 |
Pentobarbital enhances gamma-aminobutyric acid-mediated excitation without altering synaptic plasticity in rat hippocampus.
Topics: Adjuvants, Anesthesia; Animals; Baclofen; Bicarbonates; Bicuculline; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neuronal Plasticity; Neurons; Pentobarbital; Rats; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Time Factors | 2007 |
Hibernation induces pentobarbital insensitivity in medulla but not cortex.
Topics: Action Potentials; Allosteric Regulation; Animals; Bicuculline; Body Temperature; Cerebral Cortex; GABA Agonists; GABA Antagonists; GABA Modulators; Hibernation; In Vitro Techniques; Ligands; Medulla Oblongata; Muscimol; Pentobarbital; Protein Conformation; Protein Subunits; Receptors, GABA-A; Respiratory Center; Sciuridae; Seasons; Solitary Nucleus; Time Factors | 2009 |
Changes in ventral respiratory column GABAaR ε- and δ-subunits during hibernation mediate resistance to depression by EtOH and pentobarbital.
Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; Ethanol; GABA-A Receptor Antagonists; Gene Expression; Gene Expression Regulation; Hibernation; Medulla Oblongata; Neurons; Pentobarbital; Protein Subunits; Receptors, GABA-A; Sciuridae; Solitary Nucleus; Synapses; Synaptophysin | 2011 |
Yokukansan enhances pentobarbital-induced sleep in socially isolated mice: possible involvement of GABA(A)-benzodiazepine receptor complex.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Male; Medicine, Kampo; Mice; Mice, Inbred Strains; Pentobarbital; Receptors, GABA-A; Sleep; Sleep Wake Disorders; Social Isolation; Stress, Psychological | 2011 |
Increased GABA(A) receptor ε-subunit expression on ventral respiratory column neurons protects breathing during pregnancy.
Topics: Anesthesia; Animals; Base Sequence; Bicuculline; Brain Stem; Cerebral Cortex; Electrophysiological Phenomena; Female; GABA Antagonists; Gene Expression Regulation; Hypercapnia; Hypoxia; Immunohistochemistry; In Vitro Techniques; Male; Medulla Oblongata; Molecular Sequence Data; Neurons; Pentobarbital; Phrenic Nerve; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Neurokinin-1; Respiration; RNA, Messenger | 2012 |
Expression of the γ2-subunit distinguishes synaptic and extrasynaptic GABA(A) receptors in NG2 cells of the hippocampus.
Topics: Animals; Benzodiazepines; Bicuculline; Diazepam; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Muscimol; Neuroglia; Neurons; Patch-Clamp Techniques; Pentobarbital; Protein Subunits; Receptors, GABA-A; Synapses | 2013 |
Positive effects of β-amyrin on pentobarbital-induced sleep in mice via GABAergic neurotransmitter system.
Topics: Animals; Bicuculline; Brain; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice, Inbred ICR; Molecular Structure; Oleanolic Acid; Pentobarbital; Random Allocation; Sleep; Sleep Aids, Pharmaceutical; Time Factors; Wakefulness-Promoting Agents | 2015 |
Acute pentobarbital treatment impairs spatial learning and memory and hippocampal long-term potentiation in rats.
Topics: Animals; Bicuculline; Biophysics; Dose-Response Relationship, Drug; Electric Stimulation; Escape Reaction; GABA-A Receptor Antagonists; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Learning Disabilities; Long-Term Potentiation; Male; Maze Learning; Memory Disorders; Pentobarbital; Rats; Rats, Sprague-Dawley; Reaction Time; Spatial Learning; Time Factors | 2015 |
Persistent GABAA/C responses to gabazine, taurine and beta-alanine in rat hypoglossal motoneurons.
Topics: Animals; beta-Alanine; Bicuculline; Brain Stem; Central Nervous System Agents; Chlorine; GABA Agents; Hypoglossal Nerve; Midazolam; Motor Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Pentobarbital; Phosphinic Acids; Pregnanolone; Pyridazines; Pyridines; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Strychnine; Taurine; Tissue Culture Techniques | 2016 |
Zerumbone, a major sesquiterpene from Syringa pinnatifolia Hemsl., exerts the sedative effect by regulating GABAergic nervous system.
Topics: Animals; Bicuculline; Chlorides; Flumazenil; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Mice; Molecular Docking Simulation; Nervous System; Pentobarbital; Plant Extracts; Rats; Receptors, GABA-A; Sesquiterpenes; Syringa | 2023 |