bicuculline has been researched along with naloxone in 157 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 51 (32.48) | 18.7374 |
| 1990's | 57 (36.31) | 18.2507 |
| 2000's | 24 (15.29) | 29.6817 |
| 2010's | 21 (13.38) | 24.3611 |
| 2020's | 4 (2.55) | 2.80 |
| Authors | Studies |
|---|---|
| Gilfillan, K; Heap, Y; McLennan, H | 1 |
| Bruinvels, J; de Boer, T; Metselaar, HJ | 1 |
| Burchfiel, JL; Duffy, FH; Snodgrass, SR | 1 |
| Rivier, C; Vale, W | 1 |
| Ho, IK; Loh, HH; Way, EL | 1 |
| Pinnock, RD | 2 |
| Rochford, J; Stewart, J | 1 |
| Gillis, RA; Pineo, S; Taveira Da Silva, AM | 1 |
| Brandão, ML; Coimbra, NC; Tomaz, C | 1 |
| Iasnetsov, VV; Novikov, VE; Sharov, AN | 1 |
| Badoer, E; Chalmers, J | 1 |
| Desban, M; Gauchy, C; Glowinski, J; Kemel, ML | 1 |
| Inokuchi, H; Nishi, S; Polosa, C; Trzebski, A; Yoshimura, M | 1 |
| De Koninck, Y; Henry, JL | 1 |
| Miñano, FJ; Sancibrian, M; Serrano, JS | 1 |
| Jackson, HC; Nutt, DJ | 1 |
| Chalmers, J; Drolet, G; Morilak, DA | 1 |
| Harrison, NL; Lambert, NA; Teyler, TJ | 1 |
| Desban, M; Gauchy, C; Glowinski, J; Kemel, ML; Krebs, MO | 2 |
| Herrera-Marschitz, M; Reid, MS; Ungerstedt, U | 1 |
| Chrobak, JJ; Hanin, I; Napier, TC; Walsh, TJ | 1 |
| Bidzseranova, A; Penke, B; Telegdy, G; Tóth, G | 1 |
| Giordano, J | 1 |
| Han, JS; Yu, LC | 1 |
| Persson, B; Rubenson, A; Sillén, U | 1 |
| Ji, CF; Li, CY; Zhu, LX | 1 |
| Masotto, C; Negro-Vilar, A; Wisniewski, G | 1 |
| Baba, S; Takeda, T; Tanaka, C; Taniyama, K | 1 |
| Gallagher, JP; Twery, MJ | 1 |
| Pang, K; Rose, GM | 1 |
| Gu, YH; Wei, D | 2 |
| Suzuki, Y; Taguchi, K | 1 |
| Castellano, C; Introini-Collison, IB; McGaugh, JL; Pavone, F | 1 |
| Aston-Jones, G; Ennis, M | 1 |
| Bueno, L; Fargeas, MJ; Fioramonti, J | 1 |
| Skarphedinsson, JO; Thorén, P | 1 |
| Alho, H; Fujimoto, M; Geffard, M; Guidotti, A; Hanbauer, I; Kataoka, Y; Kelly, GD | 1 |
| Clarke, RJ; de Azeredo, FA; Guedes, RC; Hicks, TP; Tashiro, T | 1 |
| Dowell, RT; Eldridge, FL; Paydarfar, D; Scott, SC | 1 |
| Agmo, A; Tarasco, C | 1 |
| Gale, K; Garant, DS | 1 |
| Ho, IK; Sivam, SP | 2 |
| Burchfiel, JL; Duffy, FH; Joy, RM; Mower, GD; Snodgrass, SR | 1 |
| Hori, N; Kastuda, N; Nakanishi, H | 1 |
| Kulkarni, SK; Kunchandy, J | 1 |
| Li, P; Wang, Q | 1 |
| Kavaliers, M; Wiebe, JP | 2 |
| Djavdan, M; Zarrindast, MR | 1 |
| Henry, JL; Salter, MW | 1 |
| Gala, RR; Haisenleder, DJ | 1 |
| Murakoshi, T; Otsuka, M | 1 |
| Foong, FW; Satoh, M | 1 |
| Overstreet, D; Pilotto, R; Singer, G | 1 |
| Massotti, M; Sagratella, S | 1 |
| Lovick, TA; Wolstencroft, JH | 1 |
| DeFeudis, FV; Jadot, G; Mandel, P; Mesdjian, E; Valli, M | 1 |
| Ignatov, IuD; Petrova, IuV; Poshivalov, VP | 1 |
| Foote, F; Gale, K | 1 |
| DeFeudis, FV; Grognet, A; Hertz, F | 1 |
| Eldridge, FL; Millhorn, DE; Waldrop, TG | 1 |
| Curtis, DR; Leah, JD; Malik, R | 1 |
| Winter, JC | 1 |
| Kneip, J; Levine, AS; Morley, JE; Murray, SS | 1 |
| LaBella, FS; Sawynok, J | 1 |
| Henry, JL | 1 |
| Imura, H; Katakami, H; Kato, Y; Matsushita, N; Shimatsu, A | 1 |
| de Jonge, FH; Lopes da Silva, FH; Mollevanger, WJ; Tielen, AM | 1 |
| Bowery, NG; Malcangio, M | 1 |
| Colwell, DD; Kavaliers, M | 1 |
| Randić, M; Wang, RA | 1 |
| Jinnai, K; Kimura, F | 1 |
| Lewis, DV; Xie, CW | 1 |
| Bolser, DC; Chapman, RW; Hey, JA; Kreutner, W; Krobatsch, D; Mingo, G | 1 |
| Carpenter, DO; Lin, Y | 1 |
| Ahmad, I; Lauretti, GR; Pleuvry, BJ | 1 |
| Grider, JR | 2 |
| Castellano, C; Introini-Collison, IB; McGaugh, JL | 1 |
| Chrobak, JJ; Napier, TC | 1 |
| Brotchie, JM; Crossman, AR; Maneuf, YP; Mitchell, IJ | 1 |
| Funabashi, T; Hiruma, H; Kimura, F; Sano, A | 1 |
| Moriya, H; Murayama, S; Nakaya, H; Nemoto, T; Okamoto, Y; Sekikawa, T; Suzuki, T | 1 |
| Davies, A; Gent, JP; Goodchild, CS; Guo, Z | 1 |
| Fields, HL; Pan, ZZ | 1 |
| Fields, HL; Roychowdhury, SM | 1 |
| Chieng, B; Christie, MD | 1 |
| Hao, JX; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Feng, JQ; Kendig, JJ | 1 |
| Biró, E; Penke, B; Telegdy, G | 1 |
| Haymal, B; Taleisnik, S | 1 |
| Elliott, KJ; Inturrisi, CE; Shimoyama, M; Shimoyama, N | 1 |
| Bontempi, B; Sharp, FR | 1 |
| Colwell, DD; Kavaliers, M; Perrot-Sinal, TS | 1 |
| Brodin, E; Fried, K; Gustafsson, H; Stiller, CO | 1 |
| Budai, D; Fields, HL | 1 |
| Dickenson, AH; Kerr, NC; Reeve, AJ | 1 |
| Kasaba, T; Takasaki, M; Takeshita, M | 1 |
| Behbehani, MM; Hall, CW | 1 |
| Chavkin, C; Jin, W | 1 |
| Funabashi, T; Kimura, F; Mitsushima, D | 1 |
| Asai, T; Ikeda, H; Murase, K; Randić, M | 1 |
| Mousa-Ahmadi, E; Zarrindast, MR | 1 |
| Leite-Panissi, CR; Menescal-de-Oliveira, L; Monassi, CR | 1 |
| Asai, T; Ikeda, H; Murase, K | 1 |
| Dixon, AK; Freeman, TC; Lee, K; Preston, Z; Richardson, PJ; Widdowson, L | 1 |
| Gao, X; Wu, GC; Zhang, LM; Zhang, YQ | 1 |
| Germane, S; Klusa, V; Opmane, B; Svirskis, S; Wikberg, JE | 1 |
| Aston-Jones, G; Ivanov, A | 1 |
| Bhandari, RN; Clarke, RW; Leggett, J | 1 |
| Mahmoudi, M; Zarrindast, MR | 1 |
| Castellan-Baldan, L; Coimbra, NC; Corrêa, SA; Da Silva, LA; Eichenberger, GC; Maruoka, RY; Osaki, MY; Resende, GC; Ribeiro, SJ | 1 |
| Adamik, A; Telegdy, G | 4 |
| Kawamata, M; Kawamata, T; Namiki, A; Omote, K; Toriyabe, M | 1 |
| Leite-Panissi, CR; Menescal-de-Oliveira, L | 1 |
| Brailoiu, GC; Dun, NJ; Ohtubo, Y; Wu, SY | 1 |
| Radhakrishnan, R; Rohlwing, JJ; Skyba, DA; Sluka, KA; Wright, A | 1 |
| Jia, H; Tang, JS; Xiao, DQ; Xie, YF | 1 |
| Deng, XM; Liu, SX; Wang, YW; You, XM; Zhao, ZQ | 1 |
| Carvalho, AD; Castellan-Baldan, L; Ciscato, JG; Coimbra, NC; Corrêa, SA; D'Angelo-Dias, R; de Oliveira, R; de Oliveira, RC; Felippotti, TT; Hoffmann, A; Moreira, JE; Rebouças, EC; Ribeiro, SJ | 1 |
| Ford, CP; Mark, GP; Williams, JT | 1 |
| Calvo, F; Coimbra, NC | 1 |
| da Silva, LF; Menescal-de-Oliveira, L | 1 |
| Han, JS; Liu, FY; Qu, XX; Wan, Y; Xing, GG | 1 |
| Chen, Q; Dong, L; Fu, CY; Ni, JM; Wang, R; Zhao, YL | 1 |
| Ghasemi, T; Hajimashhadi, Z; Karimian, SM; Mirzaii-Dizgah, I; Riahi, E | 1 |
| Hotta, H; Kagitani, F; Uchida, S | 1 |
| Coutinho, MR; da Silva, LF; Menescal-de-Oliveira, L | 1 |
| Prado, WA; Silva, JR; Silva, ML | 2 |
| Chen, Q; Ji, YK; Lu, SS; Mi, ZY; Su, SF; Yang, AM; Yang, QZ; Yang, SB | 1 |
| Choi, SH; Han, CH; Jang, EY; Kim, HY; Lee, BH; Lee, JH; Yang, CH | 1 |
| Micov, AM; Paranos, SLj; Stepanović-Petrović, RM; Tomić, MA | 1 |
| Ferreira, MD; Menescal-de-Oliveira, L | 2 |
| Jászberényi, M; Telegdy, G | 1 |
| Hasanein, P; Parviz, M | 1 |
| Andrade, CA; Andrade-Franzé, GM; Colombari, DS; De Luca, LA; De Oliveira, LB; Menani, JV | 1 |
| Duffy, AM; Harte-Hargrove, LC; Milner, TA; Scharfman, HE; Varga-Wesson, A | 1 |
| Bowman, BR; Goodchild, AK | 1 |
| Azizi, H; Davoudi, M; Mirnajafi-Zadeh, J; Semnanian, S | 2 |
| Bach-Rojecky, L; Drinovac Vlah, V; Lacković, Z | 1 |
| Almada, RC; Biagioni, AF; Coimbra, NC; da Silva, JA; de Freitas, RL | 1 |
| Abbasnejad, M; Esmaeili-Mahani, S; Haghani, J; Kooshki, R; Rahbar, I; Raoof, M | 1 |
| Almada, RC; Calvo, F; Coimbra, NC; da Silva Soares, R; da Silva, JA; de Paiva, YB; Medeiros, P; Roncon, CM | 1 |
| Candiotti, KA; Gitlin, M; Rodriguez-Blanco, YF; Sevilla, A; Su, C; Weller, R; Wu, J; Yang, J; Zhang, Y; Zheng, C | 1 |
| Ahmad, S; Ahn, MJ; Ali, A; Faheem, M; Khalil, AAK; Nasir, A; Nazir, N; Nisar, M; Sajjad, W; Shah, SMM; Shah, SWA; Shoaib, M; Subhan, F | 1 |
| Coimbra, NC; de Araújo Berber, RC; de Avila, DR; de Oliveira, RC; Maia Fernandes, BF; Oliveira, R; Pichinelli Maffei, TH; Santana, VC; Streg, RV; Vale, JS | 1 |
| Flores-Murrieta, FJ; Gonzalez-Cortazar, M; Herrera-Ruiz, ML; Juárez-Aragón, MC; Molina-Cabrera, J; Montiel-Ruiz, RM; Vargas-Ruiz, R; Zamilpa, A | 1 |
3 review(s) available for bicuculline and naloxone
| Article | Year |
|---|---|
The pharmacology of amblyopia.
Topics: Adult; Amblyopia; Aminobutyrates; Animals; Bicuculline; Cats; Child; GABA Antagonists; Humans; Naloxone; Quaternary Ammonium Compounds; Sensory Deprivation; Vision, Ocular; Visual Acuity; Visual Cortex | 1978 |
The pharmacology of basal forebrain involvement in cognition.
Topics: Animals; Avoidance Learning; Aziridines; beta-Endorphin; Bicuculline; Cerebral Ventricles; Choline; Cognition; Muscimol; Naloxone; Neurons; Neurotoxins; Prosencephalon; Rats; Substance P | 1991 |
GABA in morphine analgesia and tolerance.
Topics: Analgesia; Animals; Baclofen; Benzodiazepines; Bicuculline; Brain Chemistry; Cyclohexanecarboxylic Acids; Drug Tolerance; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Morphine; Muscimol; Naloxone; Picrotoxin; Rats; Receptors, GABA-A; Synaptic Transmission | 1985 |
154 other study(ies) available for bicuculline and naloxone
| Article | Year |
|---|---|
Some pharmacological observations on the analgesia induced by acupuncture in rabbits.
Topics: Acupuncture Therapy; Analgesia; Animals; Bicuculline; Electric Stimulation; Fenclonine; Naloxone; Rabbits; Sensation; Strychnine | 1977 |
Suppression of GABA-induced abstinence behaviour in naive rats by morphine and bicuculline.
Topics: Aminobutyrates; Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoquinolines; Male; Morphine; Motor Activity; Naloxone; Rats; Receptors, Drug; Receptors, Opioid; Substance Withdrawal Syndrome; Valerates; Valproic Acid | 1977 |
Effects of gamma-aminobutyric acid and histamine on prolactin secretion in the rat.
Topics: Aminobutyrates; Animals; Bicuculline; Cells, Cultured; Clonidine; Diphenhydramine; Dopamine; Drug Interactions; Estrogens; gamma-Aminobutyric Acid; Haloperidol; Histamine; Male; Morphine; Naloxone; Nerve Tissue Proteins; Phenoxybenzamine; Pituitary Gland; Progesterone; Prolactin; Rats; Thyrotropin-Releasing Hormone | 1977 |
Pharmacological manipulation of gamma-aminobutyric acid (GABA) in morphine analgesia, tolerance and physical dependence.
Topics: Alanine; Aminobutyrates; Aminooxyacetic Acid; Analgesia; Animals; Bicuculline; Biological Transport; Drug Interactions; Drug Tolerance; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Receptors, Drug; Substance Withdrawal Syndrome; Substance-Related Disorders | 1976 |
A highly selective kappa-opioid receptor agonist, CI-977, reduces excitatory synaptic potentials in the rat locus coeruleus in vitro.
Topics: Amino Acids; Analgesics; Animals; Benzofurans; Benzomorphans; Bicuculline; Depression, Chemical; Electric Stimulation; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Ligands; Locus Coeruleus; Membrane Potentials; Naloxone; Naltrexone; Picrotoxin; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1992 |
Naloxone-induced hypoalgesia: lack of involvement of the GABA-benzodiazepine receptor complex.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Diazepam; Male; Muscimol; Naloxone; Pain Measurement; Rats; Rats, Wistar; Receptors, GABA-A | 1992 |
Gamma-aminobutyric acid type A receptor blockade at the intermediate area of the ventral surface of the medulla counteracts the cardiorespiratory depression produced by intravenous midazolam.
Topics: Animals; Bicuculline; Cardiovascular System; Cats; GABA-A Receptor Antagonists; Medulla Oblongata; Midazolam; Morphine; Naloxone; Pentobarbital; Respiratory System | 1992 |
Evidence for the involvement of serotonin in the antinociception induced by electrical or chemical stimulation of the mesencephalic tectum.
Topics: Animals; Bicuculline; Brain Mapping; Electric Stimulation; Escape Reaction; gamma-Aminobutyric Acid; Male; Methysergide; Naloxone; Nociceptors; Periaqueductal Gray; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid; Sensory Thresholds; Serotonin; Superior Colliculi; Synaptic Transmission; Tectum Mesencephali | 1992 |
[A pharmacological analysis of the role of GABA- and opioidergic systems in the development of brain edema].
Topics: Animals; Bicuculline; Brain; Brain Edema; Female; Male; Mitochondria; Naloxone; Oxidative Phosphorylation; Picrotoxin; Rats; Receptors, GABA-A; Receptors, Opioid; Semicarbazides | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Interactions of endogenous opioid and excitatory amino acid inputs to the caudal ventrolateral medulla of the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; Endorphins; Heart Rate; Hemodynamics; Injections; Medulla Oblongata; Muscimol; Naloxone; Rats; Rats, Inbred WKY | 1992 |
Functional heterogeneity of the matrix compartment in the cat caudate nucleus as demonstrated by the cholinergic presynaptic regulation of dopamine release.
Topics: Acetylcholine; Animals; Atropine; Autoradiography; Bicuculline; Cats; Caudate Nucleus; Dopamine; Dynorphins; Female; gamma-Aminobutyric Acid; Male; Naloxone; Neurons; Parasympathetic Nervous System; Pempidine; Receptors, Muscarinic; Receptors, Nicotinic; Synapses; Tetrodotoxin | 1992 |
Fast inhibitory postsynaptic potentials and responses to inhibitory amino acids of sympathetic preganglionic neurons in the adult cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Atropine; Bicuculline; Cats; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Glycine; Membrane Potentials; Naloxone; Neurons; Phentolamine; Quinoxalines; Spinal Cord; Strychnine; Synapses | 1992 |
Peripheral vibration causes an adenosine-mediated postsynaptic inhibitory potential in dorsal horn neurons of the cat spinal cord.
Topics: Adenosine; Adenosine Monophosphate; Animals; Bicuculline; Cats; Evoked Potentials; Iontophoresis; Membrane Potentials; Naloxone; Neurons; Pain; Physical Stimulation; Purinergic Antagonists; Spinal Cord; Strychnine; Synapses; Theophylline; Vibration | 1992 |
Opioid and prostaglandin mechanisms involved in the effects of GABAergic drugs on body temperature.
Topics: Animals; Baclofen; Bicuculline; Body Temperature; Dose-Response Relationship, Drug; Endorphins; gamma-Aminobutyric Acid; Indomethacin; Injections, Intraperitoneal; Muscimol; Naloxone; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
Differential effects of selective mu-, kappa- and delta-opioid antagonists on electroshock seizure threshold in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electroshock; gamma-Aminobutyric Acid; Indoles; Male; Mice; Mice, Inbred Strains; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Phenytoin; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1991 |
Opioid innervation of the caudal ventrolateral medulla is not critical for the expression of the aortic depressor nerve response in the rabbit.
Topics: Animals; Aorta; Bicuculline; Blood Pressure; Electric Stimulation; Endorphins; Glutamates; Glutamic Acid; Hemorrhage; Male; Medulla Oblongata; Microinjections; Naloxone; Nervous System; Nervous System Physiological Phenomena; Rabbits | 1991 |
Evidence for mu opiate receptors on inhibitory terminals in area CA1 of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Barium; Bicuculline; Dendrites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Ion Channel Gating; Naloxone; Nerve Endings; Potassium Channels; Quinoxalines; Rats; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Role of dynorphin-containing neurons in the presynaptic inhibitory control of the acetylcholine-evoked release of dopamine in the striosomes and the matrix of the cat caudate nucleus.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Analgesics; Animals; Bicuculline; Cats; Caudate Nucleus; Dopamine; Dynorphins; Female; Male; Models, Neurological; Naloxone; Neurons; Peptide Fragments; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Synapses; Tetrodotoxin; Tyrosine | 1991 |
Effects of intranigral substance P and neurokinin A on striatal dopamine release--II. Interactions with bicuculline and naloxone.
Topics: Animals; Bicuculline; Corpus Striatum; Dopamine; Drug Combinations; Drug Interactions; Male; Naloxone; Neurokinin A; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra | 1990 |
The effects of atrial natriuretic peptide on electroconvulsive shock-induced amnesia in rats. Transmitter-mediated action.
Topics: Amnesia; Animals; Atrial Natriuretic Factor; Atropine; Avoidance Learning; Bicuculline; Electroshock; Haloperidol; Male; Memory; Methysergide; Naloxone; Phenoxybenzamine; Propranolol; Rats | 1991 |
Analgesic profile of centrally administered 2-methylserotonin against acute pain in rats.
Topics: Analgesics; Animals; Bicuculline; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Spinal; Ketanserin; Male; Mianserin; Motor Activity; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, Serotonin; Respiration; Serotonin; Serotonin Antagonists; Tropanes | 1991 |
Habenula as a relay in the descending pathway from nucleus accumbens to periaqueductal grey subserving antinociception.
Topics: Animals; Bicuculline; Efferent Pathways; Enkephalin, Methionine; Immune Sera; Injections; Morphine; Muscimol; Naloxone; Nociceptors; Nucleus Accumbens; Periaqueductal Gray; Rabbits; Thalamic Nuclei | 1990 |
Central effects of baclofen on the L-dopa induced hyperactive urinary bladder of the rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Injections, Intraventricular; Levodopa; Male; Naloxone; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1985 |
Dual action of substance P in nociception and pain modulation at spinal level.
Topics: Animals; Bicuculline; Efferent Pathways; Naloxone; Neurons; Nociceptors; Pain; Rats; Spinal Cord; Substance P | 1987 |
Different gamma-aminobutyric acid receptor subtypes are involved in the regulation of opiate-dependent and independent luteinizing hormone-releasing hormone secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine Vasopressin; Baclofen; Bicuculline; Dinoprostone; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Male; Median Eminence; Muscimol; Naloxone; Narcotics; Oxytocin; Phentolamine; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Putative mechanisms involved in excitatory and inhibitory effects of somatostatin on intestinal motility.
Topics: Acetylcholine; Animals; Bicuculline; Electric Stimulation; Female; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Somatostatin; Theophylline; Yohimbine | 1989 |
Somatostatin hyperpolarizes neurons and inhibits spontaneous activity in the rat dorsolateral septal nucleus.
Topics: Animals; Bicuculline; Brain; Calcium; Electric Stimulation; Magnesium; Male; Membrane Potentials; Naloxone; Neurons; Rats; Rats, Inbred Strains; Somatostatin; Synapses; Tetrodotoxin | 1989 |
Differential effects of methionine5-enkephalin on hippocampal pyramidal cells and interneurons.
Topics: Action Potentials; Animals; Bicuculline; Enkephalin, Methionine; Hippocampus; Interneurons; Magnesium; Male; Naloxone; Pyramidal Tracts; Rats; Rats, Inbred Strains | 1989 |
[Mechanisms underlying depressor and bradycardia effects of A1-excitation in rats].
Topics: Animals; Bicuculline; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Microinjections; Naloxone; Phentolamine; Propranolol; Rats; Rats, Inbred Strains | 1989 |
[Mechanisms underlying depressor and bradycardia effects of A5-excitation (compared with that of A1-excitation) in rats].
Topics: Animals; Bicuculline; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Microinjections; Naloxone; Phentolamine; Propranolol; Rats; Rats, Inbred Strains | 1989 |
Effects of microiontophoretically-applied morphine on the Purkinje cell in the cerebellum of the cat.
Topics: Animals; Bicuculline; Cats; Cerebellum; Female; GABA Antagonists; Iontophoresis; Male; Morphine; Naloxone; Picrotoxin; Purkinje Cells | 1989 |
Effects of naloxone and naltrexone on memory consolidation in CD1 mice: involvement of GABAergic mechanisms.
Topics: Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Naloxone; Naltrexone; Picrotoxin | 1989 |
GABA-mediated inhibition of locus coeruleus from the dorsomedial rostral medulla.
Topics: Animals; Bicuculline; Dioxanes; Evoked Potentials; gamma-Aminobutyric Acid; Idazoxan; Iontophoresis; Locus Coeruleus; Male; Medulla Oblongata; Naloxone; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains | 1989 |
Central and peripheral action of GABAA and GABAB agonists on small intestine motility in rats.
Topics: Animals; Atropine; Baclofen; Bicuculline; Electromyography; Gastrointestinal Motility; Intestine, Small; Male; Muscimol; Naloxone; Phentolamine; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Endorphin mechanisms are responsible for the beneficial effects of opioid antagonists on cerebral function during relative cerebral ischaemia in rats.
Topics: Animals; Azocines; Bicuculline; Brain; Brain Ischemia; Evoked Potentials, Somatosensory; Hemodynamics; Male; Naloxone; Rats; Rats, Inbred SHR; Receptors, Opioid; Thyrotropin-Releasing Hormone | 1988 |
Intrinsic gamma aminobutyric acid receptors modulate the release of catecholamine from canine adrenal gland in situ.
Topics: Adrenal Medulla; Animals; Baclofen; Bicuculline; Chromaffin Granules; Dogs; Electric Stimulation; Epinephrine; Female; Hexamethonium; Hexamethonium Compounds; Histocytochemistry; Isoxazoles; Muscimol; Naloxone; Norepinephrine; Receptors, GABA-A; Splanchnic Nerves | 1986 |
Opioid mechanisms involved in the slow potential change and neuronal refractoriness during cortical spreading depression.
Topics: Animals; Bicuculline; Cerebral Cortex; Cortical Spreading Depression; Electroencephalography; Electroshock; gamma-Aminobutyric Acid; Gerbillinae; Glutamates; Glutamic Acid; Injections, Intravenous; Iontophoresis; Naloxone; Rats; Rats, Inbred Strains; Reaction Time; Seizures | 1987 |
Role of endogenous adenosine in recurrent generalized seizures.
Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Cats; Cerebral Cortex; Dipyridamole; Doxapram; Naloxone; Penicillins; Receptors, Purinergic; Reference Values; Seizures; Theophylline | 1989 |
Interactions between naloxone and GABA in the control of locomotor activity in the rat.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Brain; gamma-Aminobutyric Acid; Male; Motor Activity; Naloxone; Neural Inhibition; Rats; Rats, Inbred Strains; Synaptic Transmission | 1985 |
Infusion of opiates into substantia nigra protects against maximal electroshock seizures in rats.
Topics: Animals; Bicuculline; Electroshock; Enkephalin, Methionine; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, kappa; Seizures; Substantia Nigra | 1985 |
Comparative pharmacological effects on visual cortical neurons in monocularly deprived cats.
Topics: Acetates; Amblyopia; Ammonium Chloride; Animals; Bicuculline; Cats; gamma-Aminobutyric Acid; Naloxone; Neural Inhibition; Synaptic Transmission; Visual Cortex | 1985 |
Neostriatal evoked inhibition and effects of dopamine on globus pallidal neurons in rat slice preparations.
Topics: Animals; Bicuculline; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Globus Pallidus; Male; Naloxone; Neural Inhibition; Rats; Strychnine; Synaptic Transmission | 1985 |
Naloxone-sensitive and GABAA receptor mediated analgesic response of benzodiazepines in mice.
Topics: Analgesics; Animals; Benzodiazepines; Benzodiazepinones; Bicuculline; Female; Flumazenil; Male; Mice; Naloxone; Phenytoin; Reaction Time; Receptors, GABA-A | 1987 |
Inhibition of baroreflex following microinjection of GABA or morphine into the nucleus tractus solitarii in rabbits.
Topics: Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Heart Rate; Histological Techniques; Male; Medulla Oblongata; Microinjections; Morphine; Naloxone; Pressoreceptors; Rabbits | 1988 |
Analgesic effects of the progesterone metabolite, 3 alpha-hydroxy-5 alpha-pregnan-20-one, and possible modes of action in mice.
Topics: Analgesics; Animals; Bicuculline; Brain; Calcium Channel Blockers; Flumazenil; Injections, Intraventricular; Male; Mice; Naloxone; Picrotoxin; Progesterone | 1987 |
Analgesic effects of the putative FSH-suppressing gonadal steroid, 3 alpha-hydroxy-4-pregnen-20-one: possible modes of action.
Topics: 20-alpha-Dihydroprogesterone; Analgesia; Analgesics; Animals; Bicuculline; Calcium Channel Blockers; Cerebral Ventricles; Flumazenil; Follicle Stimulating Hormone; Injections, Intraventricular; Male; Mice; Naloxone; Progesterone; Reference Values | 1988 |
GABAA-antagonists and baclofen analgesia.
Topics: Analgesia; Animals; Baclofen; Bicuculline; GABA Antagonists; Injections, Intraperitoneal; Male; Mice; Morphine; Naloxone; Picrotoxin; Time Factors | 1988 |
Evidence that adenosine mediates the depression of spinal dorsal horn neurons induced by peripheral vibration in the cat.
Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Caffeine; Cats; Dipyridamole; Injections, Intravenous; Iontophoresis; Naloxone; Neurons; Spinal Cord; Strychnine; Theophylline; Vibration | 1987 |
Restraint stress decreases afternoon plasma prolactin levels in female rats. Influence of neural antagonists and agonists on restraint-induced changes in plasma prolactin and corticosterone.
Topics: Animals; Arecoline; Atropine; Bicuculline; Corticosterone; Female; Injections, Intravenous; Morphine; Naloxone; Ovariectomy; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Pimozide; Prolactin; Propranolol; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological; Sympathomimetics | 1986 |
Respiratory reflexes in an isolated brainstem-lung preparation of the newborn rat: possible involvement of gamma-aminobutyric acid and glycine.
Topics: Animals; Animals, Newborn; Bicuculline; Brain Stem; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Lung; Naloxone; Neural Inhibition; Rats; Rats, Inbred Strains; Reflex; Respiratory Physiological Phenomena; Spinal Nerve Roots; Strychnine | 1985 |
Neurotransmitter-blocking agents influence antinociceptive effects of carbamazepine, baclofen, pentazocine and morphine on bradykinin-induced trigeminal pain.
Topics: Analgesics; Animals; Atropine; Baclofen; Bicuculline; Bradykinin; Carbamazepine; Haloperidol; Male; Methysergide; Morphine; Naloxone; Neurotransmitter Agents; Pentazocine; Rats; Rats, Inbred Strains; Sympatholytics; Trigeminal Neuralgia; Trigeminal Nucleus, Spinal | 1984 |
Self-injection of diazepam in naive rats: effects of dose, schedule and blockade of different receptors.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Extinction, Psychological; Flumazenil; Haloperidol; Male; Naloxone; Rats; Receptors, Drug; Reinforcement Schedule; Self Administration | 1984 |
Convulsant and anticonvulsant effects of opioids: relationship to GABA-mediated transmission.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Brain; Convulsants; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Morphine; Naloxone; Narcotics; Picrotoxin; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1982 |
Actions of GABA, glycine, methionine-enkephalin and beta-endorphin compared with electrical stimulation of nucleus raphe magnus on responses evoked by tooth pulp stimulation in the medial reticular formation in the cat.
Topics: Animals; beta-Endorphin; Bicuculline; Brain Stem; Cats; Dental Pulp; Electric Stimulation; Endorphins; Enkephalin, Methionine; Female; gamma-Aminobutyric Acid; Glycine; Male; Naloxone; Neurons; Raphe Nuclei; Reticular Formation; Sensation | 1983 |
Antinociceptive action of sodium valproate in the mouse.
Topics: Acetates; Analgesics; Animals; Bicuculline; Male; Mice; Naloxone; Reaction Time; Valproic Acid | 1983 |
[Pharmaco-ethological study of analgesia induced by intraspecies fighting behavior].
Topics: Aggression; Analgesia; Animals; Behavior, Animal; Bicuculline; Conflict, Psychological; Dominance-Subordination; Humans; Male; Mice; Mice, Inbred C57BL; Naloxone; Pain; Sensory Thresholds; Time Factors | 1984 |
Morphine potentiates seizures induced by GABA antagonists and attenuates seizures induced by electroshock in the rat.
Topics: Animals; Bicuculline; Drug Synergism; Electroshock; GABA Antagonists; Isoniazid; Male; Morphine; Naloxone; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1983 |
Comparison of the analgesic actions of THIP and morphine.
Topics: Analgesics; Animals; Atropine; Benzoquinones; Bicuculline; Hypnotics and Sedatives; Isoxazoles; Male; Mice; Morphine; Naloxone; Oxazoles; Quinones; Reaction Time | 1983 |
Inhibition of breathing after stimulation of muscle is mediated by endogenous opiates and GABA.
Topics: Animals; Bicuculline; Catecholamines; Cats; Endorphins; gamma-Aminobutyric Acid; Muscles; Naloxone; Respiration; Serotonin; Time Factors | 1983 |
The effects of naloxone, morphine and methionine enkephalinamide on Ia afferent terminations in the cat spinal cord.
Topics: Afferent Pathways; Animals; Bicuculline; Cats; Electric Stimulation; Enkephalin, Methionine; gamma-Aminobutyric Acid; Morphine; Muscles; Naloxone; Piperidines; Procaine; Reflex, Monosynaptic; Synapses | 1984 |
The stimulus properties of gamma-hydroxybutyrate.
Topics: Animals; Bicuculline; Conditioning, Operant; Female; Hydroxybutyrates; Lysergic Acid Diethylamide; Morphine; Naloxone; Prejudice; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Sodium Oxybate | 1981 |
GABAergic drugs, morphine and morphine tolerance: a study in relation to nociception and gastrointestinal transit in mice.
Topics: Aminooxyacetic Acid; Analgesia; Animals; Baclofen; Bicuculline; Cyclohexanecarboxylic Acids; Digestion; Digestive System; Digestive System Physiological Phenomena; Drug Tolerance; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Morphine; Muscimol; Naloxone; Nociceptors; Oxazoles; Picrotoxin | 1983 |
Peptidergic regulation of norepinephrine induced feeding.
Topics: Animals; Bicuculline; Calcitonin; Cholecystokinin; Feeding Behavior; Hormones; Hypothalamus; Injections, Intraventricular; Male; Naloxone; Norepinephrine; Peptides; Rats; Rats, Inbred Strains | 1982 |
On the involvement of GABA in the analgesia produced by baclofen, muscimol and morphine.
Topics: 4-Aminobutyrate Transaminase; Analgesia; Analgesics; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Naloxone; Picrotoxin; Transaminases | 1982 |
Pharmacological studies on the prolonged depressant effects of baclofen on lumbar dorsal horn units in the cat.
Topics: Animals; Baclofen; Bicuculline; Cats; Depression, Chemical; Drug Interactions; Electric Stimulation; Glycine; Muscimol; Naloxone; Nociceptors; Spinal Cord; Strychnine | 1982 |
Possible involvement of gamma-aminobutyric acid in growth hormone release induced by a Met5-enkephalin analog in conscious rats.
Topics: Animals; Bicuculline; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalins; gamma-Aminobutyric Acid; Growth Hormone; Hormones; Kinetics; Male; Naloxone; Picrotoxin; Rats; Rats, Inbred Strains | 1981 |
Differential effects of enkephalin within hippocampal areas.
Topics: Animals; Bicuculline; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Hippocampus; In Vitro Techniques; Naloxone; Neurons; Rats | 1981 |
Spinal cord SP release and hyperalgesia in monoarthritic rats: involvement of the GABAB receptor system.
Topics: Animals; Arthritis, Experimental; Bicuculline; Electric Stimulation; GABA-B Receptor Antagonists; Hyperalgesia; In Vitro Techniques; Male; Naloxone; Pain Measurement; Pain Threshold; Radioimmunoassay; Rats; Rats, Inbred Lew; Receptors, GABA-B; Spinal Cord; Substance P; Weight Loss | 1994 |
Decreased predator avoidance in parasitized mice: neuromodulatory correlates.
Topics: Animals; Anxiety; Avoidance Learning; Bicuculline; Cats; Coccidiosis; Dizocilpine Maleate; Eimeria; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; Male; Mice; N-Methylaspartate; Naloxone; Odorants; Picrotoxin; Predatory Behavior; Receptors, GABA-A | 1995 |
Activation of mu-opioid receptor modulates GABAA receptor-mediated currents in isolated spinal dorsal horn neurons.
Topics: Action Potentials; Amino Acid Sequence; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Sequence Data; Muscimol; Naloxone; Naltrexone; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Opioid, mu; Spinal Cord | 1994 |
Bicuculline infusions advance the timing of luteinizing hormone surge in proestrous rats: comparisons with naloxone effects.
Topics: Animals; Bicuculline; Brain; Circadian Rhythm; Estrogens; Female; Injections, Intraventricular; Luteinizing Hormone; Naloxone; Neurons; Proestrus; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid | 1994 |
Endogenous opioids regulate long-term potentiation of synaptic inhibition in the dentate gyrus of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Electric Stimulation; GABA-A Receptor Antagonists; Hippocampus; Homeostasis; In Vitro Techniques; Long-Term Potentiation; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Opioid Peptides; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 1995 |
Respiratory effects of baclofen and 3-aminopropylphosphinic acid in guinea-pigs.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Baclofen; Bicuculline; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Guinea Pigs; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Organophosphorus Compounds; Pulmonary Ventilation; Respiration; Tidal Volume | 1995 |
Direct excitatory opiate effects mediated by non-synaptic actions on rat medial vestibular neurons.
Topics: Action Potentials; Animals; Bicuculline; Calcium; Enkephalin, Leucine-2-Alanine; Iontophoresis; Magnesium; Male; Morphine; Naloxone; Neurons; Rats; Rats, Wistar; Receptors, GABA; Receptors, Opioid, delta; Receptors, Opioid, mu; Synaptic Transmission; Vestibular Nuclei | 1994 |
Role of dynorphin and GABA in the inhibitory regulation of NMDA-induced dopamine release in striosome- and matrix-enriched areas of the rat striatum.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Bicuculline; Corpus Striatum; Dopamine; Dynorphins; gamma-Aminobutyric Acid; Kinetics; Male; N-Methylaspartate; Naloxone; Neurons; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrodotoxin; Tritium | 1994 |
The activity of opioid analgesics in seizure models utilizing N-methyl-DL-aspartic acid, kainic acid, bicuculline and pentylenetetrazole.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Bicuculline; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Kainic Acid; Male; Mice; N-Methylaspartate; Naloxone; Pentylenetetrazole; Seizures | 1994 |
Interplay of somatostatin, opioid, and GABA neurons in the regulation of the peristaltic reflex.
Topics: Animals; Antibodies; Bicuculline; Colon; Enkephalin, Methionine; gamma-Aminobutyric Acid; In Vitro Techniques; Muscle Relaxation; Naloxone; Neurons; Neurotransmitter Agents; Nitric Oxide; Peristalsis; Rats; Somatostatin | 1994 |
Interaction of beta-endorphin and GABAergic drugs in the regulation of memory storage.
Topics: Animals; Avoidance Learning; beta-Endorphin; Bicuculline; Conditioning, Classical; Dose-Response Relationship, Drug; Electroshock; Fear; Injections, Intraperitoneal; Male; Mice; Muscimol; Naloxone; Naltrexone; Picrotoxin; Reaction Time; Receptors, GABA; Receptors, Opioid; Retention, Psychology | 1993 |
Opioid and GABA modulation of accumbens-evoked ventral pallidal activity.
Topics: Action Potentials; Animals; Bicuculline; Electric Stimulation; Electrodes; Endorphins; gamma-Aminobutyric Acid; Globus Pallidus; Iontophoresis; Male; Morphine; Naloxone; Norepinephrine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1993 |
On the role of enkephalin cotransmission in the GABAergic striatal efferents to the globus pallidus.
Topics: Animals; Bicuculline; Corpus Striatum; Drug Combinations; Efferent Pathways; Enkephalins; gamma-Aminobutyric Acid; Globus Pallidus; Male; Motor Activity; Naloxone; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Reserpine; Synaptic Transmission | 1994 |
Effects of gamma-aminobutyric acid-A receptor antagonist, bicuculline, on the electrical activity of luteinizing hormone-releasing hormone pulse generator in the ovariectomized rat.
Topics: Animals; Bicuculline; Electrophysiology; Female; GABA-A Receptor Antagonists; Gonadotropin-Releasing Hormone; Hypothalamus; Luteinizing Hormone; Muscimol; Naloxone; Ovariectomy; Rats; Rats, Wistar | 1993 |
Effects of GABAergic drugs on the recovery of reflex potentials after spinal cord ischemia in cats.
Topics: Animals; Bicuculline; Cats; Female; Ischemia; Male; Membrane Potentials; Naloxone; Receptors, GABA; Reflex; Spinal Cord Injuries; Time Factors | 1995 |
Antinociceptive actions of intrathecal xylazine: interactions with spinal cord opioid pathways.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bicuculline; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Fentanyl; Idazoxan; Imidazoles; Male; Naloxone; Nociceptors; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid; Spinal Cord; Xylazine | 1996 |
Endogenous opioid-mediated inhibition of putative pain-modulating neurons in rat rostral ventromedial medulla.
Topics: Animals; Bicuculline; Brain Mapping; Enkephalins; Evoked Potentials; Male; Medulla Oblongata; Morphine; Naloxone; Nerve Endings; Neurons; Pain; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Reflex | 1996 |
Endogenous opioids acting at a medullary mu-opioid receptor contribute to the behavioral antinociception produced by GABA antagonism in the midbrain periaqueductal gray.
Topics: Animals; Bicuculline; Brain Mapping; GABA Antagonists; Male; Medulla Oblongata; Mesencephalon; Microinjections; Models, Neurological; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Time Factors | 1996 |
Local opioid withdrawal in rat single periaqueductal gray neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Baclofen; Bicuculline; Clonidine; Drug Tolerance; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Male; Membrane Potentials; Morphine; Naloxone; Narcotic Antagonists; Neurons; Organ Culture Techniques; Periaqueductal Gray; Potassium Channels; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Substance Withdrawal Syndrome; Tetrodotoxin; Time Factors; Valine | 1996 |
Nociceptin or antinociceptin: potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-2 Receptor Antagonists; Analysis of Variance; Animals; Bicuculline; Electromyography; Electroshock; Female; GABA-A Receptor Antagonists; Imidazoles; Injections, Spinal; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Nerve Fibers; Nociceptin; Opioid Peptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Cord; Sural Nerve | 1996 |
Propofol potentiates the depressant effect of alfentanil in isolated neonatal rat spinal cord and blocks naloxone-precipitated hyperresponsiveness.
Topics: Alfentanil; Analgesics, Opioid; Anesthetics, Intravenous; Animals; Animals, Newborn; Bicuculline; Depression, Chemical; Drug Synergism; Evoked Potentials; GABA Antagonists; Naloxone; Narcotic Antagonists; Propofol; Rats; Rats, Sprague-Dawley; Spinal Cord | 1997 |
Role of different neurotransmitter systems in the cholecystokinin octapeptide-induced anxiogenic response in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Atropine; Bicuculline; Dopamine Antagonists; GABA Antagonists; Haloperidol; Injections, Intraventricular; Male; Methysergide; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar; Serotonin Antagonists; Sincalide | 1997 |
Dual effect of electrochemical stimulation of the medial preoptic area on the release of LH: possible neurotransmitter involvement.
Topics: Animals; Bicuculline; Electric Stimulation; Electrodes, Implanted; Female; GABA Antagonists; Luteinizing Hormone; Methysergide; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Ovulation; Preoptic Area; Rats; Serotonin Antagonists; Stimulation, Chemical | 1997 |
Gabapentin enhances the antinociceptive effects of spinal morphine in the rat tail-flick test.
Topics: Acetates; Amines; Analgesics; Animals; Bicuculline; Cyclohexanecarboxylic Acids; Drug Combinations; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Morphine; Movement; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Tail | 1997 |
Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area.
Topics: Afferent Pathways; Analgesics, Opioid; Animals; Behavior, Animal; Benzazepines; Bicuculline; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Injections; Injections, Intraperitoneal; Interneurons; Morphine; Motor Activity; Naloxone; Nerve Tissue Proteins; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substantia Nigra; Tegmentum Mesencephali | 1997 |
Opioid and non-opioid NMDA-mediated predator-induced analgesia in mice and the effects of parasitic infection.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acids; Analgesia; Animals; Behavior, Animal; Bicuculline; Butyrates; Butyric Acid; Excitatory Amino Acid Antagonists; GABA Antagonists; Histamine Antagonists; Host-Parasite Interactions; Male; Mice; Mice, Inbred Strains; Naloxone; Narcotic Antagonists; Nematospiroides dubius; Nociceptors; Odorants; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Serotonin Receptor Agonists; Stress, Physiological; Strongylida Infections; Time Factors | 1997 |
Opioid-induced release of neurotensin in the periaqueductal gray matter of freely moving rats.
Topics: Analgesics, Opioid; Animals; Bicuculline; Calcium; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Agonists; GABA Antagonists; Male; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Narcotics; Neurotensin; Periaqueductal Gray; Rats; Rats, Sprague-Dawley | 1997 |
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; GABA Antagonists; Hot Temperature; Iontophoresis; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Peptide Fragments; Peptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail | 1998 |
Spinal effects of bicuculline: modulation of an allodynia-like state by an A1-receptor agonist, morphine, and an NMDA-receptor antagonist.
Topics: Adenosine; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Kynurenic Acid; Male; Morphine; Naloxone; Nerve Fibers; Neurons; Pain; Physical Stimulation; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Touch | 1998 |
[The effects of flumazenil or bicuculline on the respiratory depression by morphine].
Topics: Action Potentials; Animals; Bicuculline; Depression, Chemical; Flumazenil; GABA Antagonists; GABA Modulators; Morphine; Naloxone; Narcotic Antagonists; Phrenic Nerve; Rats; Respiration; Respiratory Insufficiency | 1998 |
Synaptic effects of nitric oxide on enkephalinergic, GABAergic, and glutamatergic networks of the rat periaqueductal gray.
Topics: Animals; Bicuculline; Blood Pressure; Enkephalins; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Hydroxylamine; Imidazoles; Male; Membrane Potentials; Naloxone; Nerve Net; Neural Inhibition; Nitric Oxide; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Synapses | 1998 |
Regulation of excitatory neural input to longitudinal intestinal muscle by myenteric interneurons.
Topics: Animals; Bicuculline; Colon; Dimethylphenylpiperazinium Iodide; Enkephalin, Methionine; gamma-Aminobutyric Acid; Ganglia, Autonomic; In Vitro Techniques; Interneurons; Models, Neurological; Muscle, Smooth; Myenteric Plexus; Naloxone; Neurotransmitter Agents; Nitric Oxide; Nitroarginine; Peptide Fragments; Rats; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1998 |
Mu opioids enhance mossy fiber synaptic transmission indirectly by reducing GABAB receptor activation.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Antagonists; Long-Term Potentiation; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Naloxone; Narcotic Antagonists; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission | 1999 |
Fos expression in gonadotropin-releasing hormone neurons by naloxone or bicuculline in intact male rats.
Topics: Animals; Bicuculline; GABA Antagonists; Gonadotropin-Releasing Hormone; Immunohistochemistry; Infusions, Intravenous; Luteinizing Hormone; Male; Naloxone; Narcotic Antagonists; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar | 1999 |
Robust suppression of afferent-induced excitation in the rat spinal dorsal horn after conditioning low-frequency stimulation.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Bicuculline; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Naloxone; Nerve Fibers; Neuronal Plasticity; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Reaction Time; Strychnine | 1999 |
Effects of GABAergic system on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Morphine Dependence; Muscimol; Naloxone; Narcotic Antagonists; Organophosphorus Compounds; Picrotoxin; Substance Withdrawal Syndrome | 1999 |
Ventrolateral periaqueductal gray matter and the control of tonic immobility.
Topics: Animals; Bicuculline; Brain Mapping; Carbachol; Escape Reaction; Guinea Pigs; Male; Microinjections; Morphine; Muscimol; Naloxone; Neural Pathways; Periaqueductal Gray; Posture; Restraint, Physical | 1999 |
Robust changes of afferent-induced excitation in the rat spinal dorsal horn after conditioning high-frequency stimulation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Chlorides; Conditioning, Psychological; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine Agents; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neuronal Plasticity; Optics and Photonics; Pain; Posterior Horn Cells; Potassium; Rats; Rats, Sprague-Dawley; Spinal Nerve Roots; Strychnine | 2000 |
Adenosine receptor expression and function in rat striatal cholinergic interneurons.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Baclofen; Bicuculline; Caffeine; Cholinergic Fibers; Corpus Striatum; Dose-Response Relationship, Drug; GABA Antagonists; Gene Expression; Male; Membrane Potentials; Naloxone; Narcotic Antagonists; Neurons; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Tritium; Xanthines | 2000 |
The release of serotonin in rat spinal dorsal horn and periaqueductal gray following carrageenan inflammation.
Topics: Animals; Bicuculline; Carrageenan; Cerebral Ventricles; Hydroxyindoleacetic Acid; Inflammation; Injections, Intraventricular; Kinetics; Male; Microdialysis; Naloxone; Periaqueductal Gray; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Time Factors | 2000 |
The gamma(2)-MSH peptide mediates a central analgesic effect via a GABA-ergic mechanism that is independent from activation of melanocortin receptors.
Topics: alpha-MSH; Analgesics; Animals; Bicuculline; Catalepsy; Central Nervous System Depressants; Diazepam; Drug Interactions; Ethanol; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; gamma-MSH; Male; Mice; Mice, Inbred BALB C; Muscimol; Naloxone; Narcotic Antagonists; Nociceptors; Pain Threshold; Peptides, Cyclic; Receptors, Corticotropin; Receptors, Melanocortin; Tail | 2001 |
Local opiate withdrawal in locus coeruleus neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Barium; Bicuculline; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Kynurenic Acid; Locus Coeruleus; Male; Membrane Potentials; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Neurons; Ouabain; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tetrodotoxin; Thionucleotides | 2001 |
Opioid and GABA receptors involved in mediation and modulation of tonic and stimulus-evoked inhibition of a spinal reflex in the decerebrated and spinalized rabbit.
Topics: Animals; Bicuculline; Conditioning, Classical; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Methionine; Female; GABA Antagonists; Male; Muscle Tonus; Naloxone; Naltrexone; Narcotic Antagonists; Organophosphorus Compounds; Rabbits; Receptors, GABA; Receptors, Opioid; Receptors, Opioid, mu; Receptors, sigma; Reflex | 2001 |
GABA mechanisms and antinociception in mice with ligated sciatic nerve.
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; Ligation; Male; Mice; Mice, Inbred Strains; Morphine; Muscimol; Naloxone; Organophosphorus Compounds; Pain; Pain Measurement; Sciatic Nerve | 2001 |
Neuroanatomical and psychopharmacological evidence for interaction between opioid and GABAergic neural pathways in the modulation of fear and defense elicited by electrical and chemical stimulation of the deep layers of the superior colliculus and dorsal
Topics: Aggression; Animals; Bicuculline; Electric Stimulation; Fear; GABA Antagonists; Immunohistochemistry; Male; Mesencephalon; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Neurons; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, GABA; Receptors, Opioid; Stimulation, Chemical; Superior Colliculi | 2002 |
The action of orexin A on passive avoidance learning. Involvement of transmitters.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Avoidance Learning; Bicuculline; Carrier Proteins; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; GABA Antagonists; Haloperidol; Injections, Intraventricular; Intracellular Signaling Peptides and Proteins; Male; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Neuropeptides; Neurotransmitter Agents; Nitric Oxide Synthase; Orexins; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar | 2002 |
Intracerebroventricular morphine produces antinociception by evoking gamma-aminobutyric acid release through activation of 5-hydroxytryptamine 3 receptors in the spinal cord.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Spinal Cord | 2002 |
Central nucleus of the amygdala and the control of tonic immobility in guinea pigs.
Topics: Amygdala; Animals; Bicuculline; Carbachol; Cholinergic Agonists; Fear; GABA Agonists; GABA Antagonists; Guinea Pigs; Male; Microinjections; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Narcotics; Reflex, Startle | 2002 |
Effects of endomorphin on substantia gelatinosa neurons in rat spinal cord slices.
Topics: Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Postsynaptic Potentials; Female; Male; Membrane Potentials; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord; Substantia Gelatinosa; Tetrodotoxin; Time Factors | 2003 |
Joint manipulation reduces hyperalgesia by activation of monoamine receptors but not opioid or GABA receptors in the spinal cord.
Topics: Adrenergic alpha-Antagonists; Animals; Bicuculline; GABA Antagonists; Hyperalgesia; Joints; Male; Methysergide; Naloxone; Narcotic Antagonists; Pain; Pain Management; Physical Stimulation; Physical Therapy Modalities; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, GABA; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Yohimbine | 2003 |
Involvement of GABAergic modulation of the nucleus submedius (Sm) morphine-induced antinociception.
Topics: Analgesics, Opioid; Animals; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Nociceptors; Pain Threshold; Rats; Rats, Sprague-Dawley; Reflex; Tail; Thalamic Nuclei | 2004 |
Effects of pituitary adenylate cyclase polypeptide (PACAP) on extinction of active avoidance learning in rats: involvement of neurotransmitters.
Topics: Adrenergic beta-Antagonists; Animals; Avoidance Learning; Bicuculline; Dopamine Antagonists; Enzyme Inhibitors; GABA Antagonists; Haloperidol; Male; Naloxone; Narcotic Antagonists; Nerve Growth Factors; Neuropeptides; Neurotransmitter Agents; Nitroarginine; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Propranolol; Rats; Rats, Wistar | 2005 |
Involvement of GABA and opioid peptide receptors in sevoflurane-induced antinociception in rat spinal cord.
Topics: Anesthetics, Inhalation; Animals; Bicuculline; Dose-Response Relationship, Drug; Electromyography; GABA-A Receptor Antagonists; Male; Methyl Ethers; Naloxone; Narcotic Antagonists; Nerve Fibers, Unmyelinated; Nociceptors; Rats; Rats, Sprague-Dawley; Sevoflurane; Spinal Cord | 2005 |
Functional and ultrastructural neuroanatomy of interactive intratectal/tectonigral mesencephalic opioid inhibitory links and nigrotectal GABAergic pathways: involvement of GABAA and mu1-opioid receptors in the modulation of panic-like reactions elicited b
Topics: Animals; Bicuculline; Electric Stimulation; GABA Antagonists; Male; Mesencephalon; Microscopy, Electron; Naloxone; Narcotic Antagonists; Neural Pathways; Neurons; Panic; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, mu; Substantia Nigra; Tectum Mesencephali | 2005 |
Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location.
Topics: Amygdala; Analgesics; Animals; Bicuculline; Biotin; Cell Count; Dopamine; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Female; GABA Antagonists; Immunohistochemistry; In Vitro Techniques; Limbic System; Male; Membrane Potentials; Mice; Mice, Inbred DBA; Microinjections; Molecular Sequence Data; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neural Pathways; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Reaction Time; Serotonin; Serotonin Receptor Agonists; Synaptic Transmission; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2006 |
Interactions between opioid-peptides-containing pathways and GABA(A)-receptors-mediated systems modulate panic-like-induced behaviors elicited by electric and chemical stimulation of the inferior colliculus.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Drug Interactions; Electric Stimulation; Freezing Reaction, Cataleptic; GABA Antagonists; Inferior Colliculi; Male; Morphine; Naloxone; Narcotic Antagonists; Neural Pathways; Opioid Peptides; Pain; Rats; Rats, Wistar; Receptors, GABA-A; Stimulation, Chemical | 2006 |
Role of opioidergic and GABAergic neurotransmission of the nucleus raphe magnus in the modulation of tonic immobility in guinea pigs.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Immobility Response, Tonic; Male; Microinjections; Models, Neurological; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Raphe Nuclei | 2007 |
Long-term synaptic plasticity in the spinal dorsal horn and its modulation by electroacupuncture in rats with neuropathic pain.
Topics: Action Potentials; Animals; Bicuculline; Dizocilpine Maleate; Drug Combinations; Electroacupuncture; Excitatory Amino Acid Antagonists; GABA Antagonists; Hyperesthesia; Ligation; Long-Term Synaptic Depression; Male; Methysergide; Naloxone; Narcotic Antagonists; Nerve Fibers, Unmyelinated; Neuralgia; Neuronal Plasticity; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Nerves; Synapses; Time Factors | 2007 |
In vivo characterization of the effects of human hemokinin-1 and human hemokinin-1(4-11), mammalian tachykinin peptides, on the modulation of pain in mice.
Topics: Analgesics; Animals; Benzamides; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Humans; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Tachykinins; Tropanes | 2008 |
Attenuation of morphine withdrawal signs by muscimol in the locus coeruleus of rats.
Topics: Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Locus Coeruleus; Male; Morphine Dependence; Muscimol; Naloxone; Narcotic Antagonists; Organophosphorus Compounds; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2008 |
Mechanism of the reflex inhibition of heart rate elicited by acupuncture-like stimulation in anesthetized rats.
Topics: Acupuncture Points; Afferent Pathways; Anesthesia; Animals; Bicuculline; Bradycardia; Electric Stimulation; GABA Antagonists; Heart Rate; Injections, Intravenous; Male; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Neural Inhibition; Neurons; Rats; Rats, Wistar; Reflex; Skin; Sympathetic Nervous System; Tibial Nerve; Vagotomy | 2008 |
Opioidergic and GABAergic mechanisms in the rostral ventromedial medulla modulate the nociceptive response of vocalization in guinea pigs.
Topics: Analgesics, Opioid; Animals; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Medulla Oblongata; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Vocalization, Animal | 2010 |
Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the activation of different descending pain inhibitory mechanisms.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Antagonists; Analgesia; Anesthetics, Intravenous; Animals; Atropine; Baclofen; Bicuculline; Biophysics; Dioxanes; Disease Models, Animal; Electroacupuncture; GABA Agents; Male; Methysergide; Models, Biological; Multivariate Analysis; Naloxone; Narcotic Antagonists; Pain; Pain Management; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Serotonin Antagonists; Tail; Thiopental; Time Factors | 2011 |
Intracerebroventricular administration of neuronostatin induces depression-like effect in forced swim test of mice.
Topics: Affect; Animals; Bicuculline; Depression; GABA-A Receptor Antagonists; Infusions, Intraventricular; Male; Melanocyte-Stimulating Hormones; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Peptide Hormones; Receptor, Melanocortin, Type 3; Receptors, GABA-A; Solid-Phase Synthesis Techniques; Swimming; Time Factors | 2011 |
Effect of acupuncture on naloxone-precipitated withdrawal syndrome in morphine-experienced rats: the mediation of GABA receptors.
Topics: Acupuncture Points; Acupuncture Therapy; Animals; Bicuculline; Diarrhea; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Morphine; Morphine Dependence; Morpholines; Muscle Contraction; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Substance Withdrawal Syndrome; Tremor | 2011 |
The mechanisms of antihyperalgesic effect of topiramate in a rat model of inflammatory hyperalgesia.
Topics: Analgesics; Animals; Bicuculline; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Fructose; Hyperalgesia; Inflammation; Male; Naloxone; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Receptors, Opioid; Topiramate; Yohimbine | 2013 |
Opioidergic, GABAergic and serotonergic neurotransmission in the dorsal raphe nucleus modulates tonic immobility in guinea pigs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Bicuculline; Drug Interactions; GABAergic Neurons; Guinea Pigs; Immobility Response, Tonic; Male; Microinjections; Morphine; Muscimol; Naloxone; Opioid Peptides; Raphe Nuclei; Serotonergic Neurons; Serotonin; Serotonin 5-HT2 Receptor Agonists; Synaptic Transmission | 2012 |
Involvement of transmitters in the anxiolytic action of urocortin 3 in mice.
Topics: Analysis of Variance; Animals; Anxiety; Atropine; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Male; Maze Learning; Methysergide; Mice; Naloxone; Neurotransmitter Agents; Propranolol; Time Factors; Urocortins | 2013 |
Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the anterior pretectal nucleus.
Topics: Analgesia; Animals; Atropine; Bicuculline; Electroacupuncture; GABA-A Receptor Antagonists; Male; Mesencephalon; Methiothepin; Methysergide; Muscarinic Antagonists; Naloxone; Naltrexone; Narcotic Antagonists; Pain Management; Rats; Rats, Wistar; Serotonin Antagonists; Somatostatin | 2013 |
Transmitter mediation of the anxiolytic action of apelin-13 in male mice.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Atropine; Bicuculline; Dopamine Antagonists; GABA-A Receptor Antagonists; Haloperidol; Intercellular Signaling Peptides and Proteins; Male; Maze Learning; Methysergide; Mice; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Propranolol; Receptors, Neurotransmitter; Serotonin Antagonists | 2014 |
Nociceptive vocalization response in guinea pigs modulated by opioidergic, GABAergic and serotonergic neurotransmission in the dorsal raphe nucleus.
Topics: Analgesics, Opioid; Animals; Bicuculline; Dorsal Raphe Nucleus; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Nociception; Serotonin; Synaptic Transmission; Vocalization, Animal | 2014 |
Role of GABAA receptor in modulation of acute thermal pain using a rat model of cholestasis.
Topics: Acute Pain; Animals; Bicuculline; Cholestasis; Disease Models, Animal; Muscimol; Naloxone; Rats; Receptors, GABA-A; Rotarod Performance Test | 2014 |
Gabaergic and opioid receptors mediate the facilitation of NaCl intake induced by α₂-adrenergic activation in the lateral parabrachial nucleus.
Topics: Animals; Antihypertensive Agents; Baclofen; Bicuculline; Captopril; Enzyme Inhibitors; Furosemide; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; Imidazoles; Male; Naloxone; Narcotic Antagonists; Parabrachial Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, GABA; Receptors, Opioid; Sodium Chloride; Sodium Potassium Chloride Symporter Inhibitors | 2015 |
Neurotransmitter-mediated anxiogenic action of PACAP-38 in rats.
Topics: Adrenergic Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Arginine; Atropine; Bicuculline; Dopamine Antagonists; Exploratory Behavior; Haloperidol; Male; Maze Learning; Methysergide; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Nitroso Compounds; Peptide Fragments; Phenoxybenzamine; Pituitary Adenylate Cyclase-Activating Polypeptide; Propranolol; Rats; Rats, Wistar; Receptors, GABA; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Opioid receptor-dependent sex differences in synaptic plasticity in the hippocampal mossy fiber pathway of the adult rat.
Topics: Animals; Baclofen; Bicuculline; Dendritic Spines; Estrous Cycle; Female; GABA-A Receptor Antagonists; Hippocampus; Long-Term Potentiation; Male; Mossy Fibers, Hippocampal; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Sex Characteristics; Somatostatin; Synapses | 2015 |
GABA and enkephalin tonically alter sympathetic outflows in the rat spinal cord.
Topics: Adipose Tissue, Brown; Animals; Bicuculline; Blood Pressure; Body Temperature; Enkephalins; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Heart Rate; Male; Naloxone; Narcotic Antagonists; Protein Precursors; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Opioid, delta; Receptors, Opioid, mu; RNA, Messenger; Spinal Cord; Sympathetic Nervous System | 2015 |
The blockade of GABAA receptors attenuates the inhibitory effect of orexin type 1 receptors antagonist on morphine withdrawal syndrome in rats.
Topics: Animals; Benzoxazoles; Bicuculline; GABA-A Receptor Antagonists; Locus Coeruleus; Male; Microinjections; Morphine; Naloxone; Naphthyridines; Narcotic Antagonists; Orexin Receptor Antagonists; Orexin Receptors; Rats, Wistar; Substance Withdrawal Syndrome; Urea | 2016 |
Antinociceptive action of botulinum toxin type A in carrageenan-induced mirror pain.
Topics: Analgesics; Animals; Bicuculline; Botulinum Toxins, Type A; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Functional Laterality; Hyperalgesia; Male; Naloxone; Pain; Pain Measurement; Rats; Rats, Wistar; Spinal Cord; Synaptosomal-Associated Protein 25 | 2016 |
Panicolytic-like effects caused by substantia nigra pars reticulata pretreatment with low doses of endomorphin-1 and high doses of CTOP or the NOP receptors antagonist JTC-801 in male Rattus norvegicus.
Topics: Aminoquinolines; Analgesics, Opioid; Animals; Benzamides; Bicuculline; Dose-Response Relationship, Drug; Fear; gamma-Aminobutyric Acid; Male; Naloxone; Nociceptin; Nociceptin Receptor; Oligopeptides; Opioid Peptides; Pars Reticulata; Rats; Rats, Wistar; Receptors, Opioid; Somatostatin; Superior Colliculi | 2017 |
The effect of central administration of alpha-pinene on capsaicin-induced dental pulp nociception.
Topics: Animals; Bicuculline; Bicyclic Monoterpenes; Capsaicin; Cerebral Ventricles; Dental Pulp; Fluorescent Antibody Technique; Male; Monoterpenes; Naloxone; Nociception; Random Allocation; Rats; Rats, Wistar | 2019 |
Decrease of inhibitory synaptic currents of locus coeruleus neurons via orexin type 1 receptors in the context of naloxone-induced morphine withdrawal.
Topics: Analgesics, Opioid; Animals; Bicuculline; GABAergic Neurons; Locus Coeruleus; Male; Morphine; Naloxone; Narcotic Antagonists; Neurons; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Synaptic Potentials; Synaptic Transmission | 2019 |
The Blockade of µ1- and κ-Opioid Receptors in the Inferior Colliculus Decreases the Expression of Panic Attack-Like Behaviours Induced by Chemical Stimulation of the Dorsal Midbrain.
Topics: Animals; Behavior, Animal; Bicuculline; Exploratory Behavior; GABA-A Receptor Antagonists; Inferior Colliculi; Male; Mesencephalon; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Panic; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2019 |
The mechanism of chronic nicotine exposure and nicotine withdrawal on pain perception in an animal model.
Topics: Animals; Baclofen; Bicuculline; Disease Models, Animal; Down-Regulation; Endorphins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyperalgesia; Male; Naloxone; Nicotine; Pain Perception; Pain Threshold; Rats; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome; Time Factors; Up-Regulation | 2020 |
Evaluation of antinociceptive activity of Ilex dipyrena Wall. in mice.
Topics: Analgesics; Animals; Bicuculline; GABA-A Receptor Antagonists; Ilex; Mice, Inbred BALB C; Models, Animal; Naloxone; Narcotic Antagonists; Pain; Plant Extracts; Toxicity Tests, Acute | 2021 |
The blockade of μ‑opioid receptors in the lateral hypothalamus enhances panic attack‑like behaviour and diminishes defensive antinociception.
Topics: Animals; Behavior, Animal; Bicuculline; Fear; Hypothalamic Area, Lateral; Naloxone; Narcotic Antagonists; Nociception; Panic; Panic Disorder; Rats; Rats, Wistar; Receptors, Opioid, mu | 2022 |
Bio-guided study of the antinociceptive, anti-inflammatory, and free-radical scavenging capacity of the leaves of Rhus virens Lindh. ex A. Gray and its possible mechanism of antinociception.
Topics: Adenosine Triphosphate; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Bicuculline; Edema; Glyburide; Hexanes; Mice; Naloxone; NG-Nitroarginine Methyl Ester; Pain; Plant Extracts; Plant Leaves; Rhus | 2023 |