Page last updated: 2024-08-21

bicuculline and morphine

bicuculline has been researched along with morphine in 116 studies

Research

Studies (116)

Timeframe	Studies, this research(%)	All Research%
pre-1990	39 (33.62)	18.7374
1990's	25 (21.55)	18.2507
2000's	32 (27.59)	29.6817
2010's	19 (16.38)	24.3611
2020's	1 (0.86)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Bruinvels, J; de Boer, T; Metselaar, HJ	1
Bulaev, VM; Ostrovskaia, RU	1
Rivier, C; Vale, W	1
Grandison, L; Guidotti, A	1
Arnt, J; Scheel-Krüger, J	1
Ho, IK; Loh, HH; Way, EL	1
Gillis, RA; Pineo, S; Taveira Da Silva, AM	1
Hosoki, R; Otsuka, M; Yanagisawa, M	1
Bagri, A; Di Scala, G; Sandner, G	1
Harris, V; Vasko, MR	1
Alberch, J; Arenas, E; Marsal, J	1
Kerr, DI; Ong, J; Prager, RH	1
Han, JS; Yu, LC	1
Aley, KO; Kulkarni, SK	1
Gale, K; Maggio, R	1
Bapna, JS; Ramaswamy, S; Suthakaran, C	1
Suzuki, Y; Taguchi, K	1
Fujii, E; Nomoto, T	1
Arasteh, K; Trulson, ME	1
Gale, K	1
Gale, K; Garant, DS	1
Ho, IK; Sivam, SP	2
Ossowska, K; Wardas, J; Wolfarth, S	1
Li, P; Wang, Q	1
Ferrario, P; Hafner, B; Mantegazza, P; Tammiso, R; Zambotti, F; Zonta, N	1
Djavdan, M; Zarrindast, MR	1
Jenck, F; Karli, P; Moreau, JL	1
Kruszewska, A	1
Gala, RR; Haisenleder, DJ	1
Fields, HL; Moreau, JL	1
Bespalova, ZhD; Mirzoian, RS; Ragimov, KhS	1
Langwiński, R; Matla, J	1
Mantegazza, P; Parenti, M; Tammiso, R; Vita, P; Zambotti, F; Zonta, N	1
Bulayev, VM; Ostrovskaya, RU; Zakusov, VV	1
Foong, FW; Satoh, M	1
Mantegazza, P; Tammiso, R; Vicentini, L; Zambotti, F; Zonta, N	1
Bruinvels, J; van der Laan, JW	1
Havemann, U; Kuschinsky, K; Turski, L	1
Massotti, M; Sagratella, S	1
Foote, F; Gale, K	1
DeFeudis, FV; Grognet, A; Hertz, F	1
Curtis, DR; Leah, JD; Malik, R	1
Winter, JC	1
Cheney, DL; McGill, W; Murray, TF	1
Kaneto, H; Rahman, AF; Takahashi, M	1
Gore, JC; Petroff, OA; Prichard, JW; Zhong, J	1
Ahmad, I; Pleuvry, BJ	1
Carpenter, DO; Lin, Y	1
Misawa, M; Nagase, H; Narita, M; Suzuki, T; Takahashi, Y	1
Brusa, L; D'Amore, A; Lorenzini, P; Massotti, M	1
Chrobak, JJ; Napier, TC	1
Beitz, AJ; Mullet, MA; Williams, FG	1
Bartolini, A; Galeotti, N; Ghelardini, C	1
Fields, HL; Pan, ZZ	1
Chieng, B; Christie, MD	1
Elliott, KJ; Inturrisi, CE; Shimoyama, M; Shimoyama, N	1
Bontempi, B; Sharp, FR	1
Brodin, E; Fried, K; Gustafsson, H; Stiller, CO	1
Dickenson, AH; Kerr, NC; Reeve, AJ	1
Kasaba, T; Takasaki, M; Takeshita, M	1
Leite-Panissi, CR; Menescal-de-Oliveira, L; Monassi, CR	1
Han, S; Jia, YS; Ju, G; Liu, QS	1
Misawa, M; Mizoguchi, H; Nagase, H; Narita, M; Suzuki, T; Takahashi-Nakano, Y; Tseng, LF; Yajima, Y	1
Schindler, CJ; Slamberová, R; Vathy, I; Velísková, J	1
Aston-Jones, G; Ivanov, A	1
Mahmoudi, M; Zarrindast, MR	2
Schindler, CJ; Slamberová, R; Vathy, I	3
Falahi, M; Ghoshooni, H; Hossein Salimi, S; Kamalnegad, M; Mohseni Astani, A; Sahraei, H; Shafaghi, B	1
Kawamata, M; Kawamata, T; Namiki, A; Omote, K; Toriyabe, M	1
Leite-Panissi, CR; Menescal-de-Oliveira, L	1
Mogil, JS; Nemmani, KV	1
Ahmadi, S; Haeri-Rohani, A; Jafari, MR; Jafari-Sabet, M; Rezayof, A; Zarrindast, MR	1
Jia, H; Tang, JS; Xiao, DQ; Xie, YF	1
Clayton, CC; Morgan, MM	1
Amiri, YA; Ghoshooni, H; Haeri-Rohani, A; Pourmotabbed, A; Sahraei, H; Salimi, SH; Sepehri, H; Zahirodin, A; Zardooz, H	1
Haeri-Rohani, A; Motamedi, F; Noorbakhshnia, M; Rezayof, A; Zarrindast, MR	1
Jia, H; Qu, CL; Tang, JS	1
Haeri-Rohani, A; Rassouli, Y; Razavi, S; Rezayof, A; Zarrindast, MR	1
Calvo, F; Coimbra, NC	1
Ghadimi, M; Ramezani-Tehrani, B; Sahebgharani, M; Zarrindast, MR	1
Cao, DQ; Chang, YT; Chen, YP; Tan, CH; Xu, JM	1
da Silva, LF; Menescal-de-Oliveira, L	1
Fathi-Azarbaijani, F; Hajizadeh-Moghaddam, A; Heidari-Darvishani, A; Jafari-Sabet, M; Rezayof, A; Zarrindast, MR	1
Choi, KH; Jang, EY; Kim, HS; Kim, JA; Kim, MR; Lee, BH; Shim, I; Yang, CH; Yoon, SS; Yun, J	1
Li, X; Xu, MY; Xu, Y	1
Baghdoyan, HA; Bowman, HR; Lydic, R; Zhu, Z	1
Heinmiller, A; Ting-A-Kee, R; van der Kooy, D; Vargas-Perez, H; Yeh, A	1
Dallel, R; Miraucourt, LS; Moisset, X; Voisin, DL	1
Dockstader, C; Grieder, T; Heinmiller, A; Ting-A-Kee, R; van der Kooy, D	1
Abe, T; Kobayashi, M; Satoh, F; Sugiyo, S; Takemura, M; Uehashi, D; Yonehara, N	1
Allison, DW; Bufalino, MR; Clarke, L; Hansen, DM; Razavi, R; Steffensen, SC; Ting-A Kee, R; van der Kooy, D; Vargas-Perez, H; Walton, CH	1
Choi, KH; Choi, SH; Hwang, M; Kim, H; Kim, KJ; Lee, BH; Lee, YK; Lim, SC; Yang, CH; Yoon, SS	1
Coutinho, MR; da Silva, LF; Menescal-de-Oliveira, L	1
Rassouli, Y; Rezayof, A; Zarrindast, MR	1
Dong, YX; Hou, Y; Sun, JY; Wang, F; Wu, CF; Yang, JY	1
Bu, Q; Cen, X; Deng, Y; Li, Y; Lv, L; Shao, X; Yan, G; Yang, Y; Zhao, J; Zhao, Y; Zhou, J; Zhu, R	1
Choi, SH; Han, CH; Jang, EY; Kim, HY; Lee, BH; Lee, JH; Yang, CH	1
Ahmadi, R; Ashabi, G; Oryan, S; Valizadegan, F	1
Ferreira, MD; Menescal-de-Oliveira, L	2
Bailey, CP; Dewey, WL; Gabra, BH; Henderson, G; Hull, LC	1
Li, G; Liang, Z; Tang, Y; Xia, J; Yang, Y; Zhou, Y	1
Kirby, LG; Li, C; Staub, DR	1
Bobeck, EN; Chen, Q; Ingram, SL; Morgan, MM	1
Chang, SC; Gwak, YS; Kim, HY; Kim, JS; Kim, NJ; Ku, JY; Lee, BH; Lee, HJ; Lee, YK; Lim, SC; Yang, CH; Zhao, RJ	1
Liu, P; Song, W; Wang, F; Wu, C; Xiang, R; Yang, J; Yang, X; Yu, L	1
Arase, M; Bertolini, JF; Fischer, L; Lima, MMS; Pontarolla, FM; Tobaldini, G; Tomim, DH	1
Azizi, H; Davoudi, M; Mirnajafi-Zadeh, J; Semnanian, S	2
Rezayof, A; Sharifi, KA; Torkaman-Boutorabi, A; Zarrindast, MR	1
Alaei, H; Amohashemi, E; Reisi, P	1

Reviews

2 review(s) available for bicuculline and morphine

Article	Year
Mechanisms of seizure control mediated by gamma-aminobutyric acid: role of the substantia nigra. Federation proceedings, 1985, Volume: 44, Issue:8 Topics: Animals; Bicuculline; Cell Compartmentation; Epilepsy; gamma-Aminobutyric Acid; Microinjections; Morphine; Muscimol; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Seizures; Substantia Nigra	1985
GABA in morphine analgesia and tolerance. Life sciences, 1985, Jul-22, Volume: 37, Issue:3 Topics: Analgesia; Animals; Baclofen; Benzodiazepines; Bicuculline; Brain Chemistry; Cyclohexanecarboxylic Acids; Drug Tolerance; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Morphine; Muscimol; Naloxone; Picrotoxin; Rats; Receptors, GABA-A; Synaptic Transmission	1985

Other Studies

114 other study(ies) available for bicuculline and morphine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Suppression of GABA-induced abstinence behaviour in naive rats by morphine and bicuculline. Life sciences, 1977, Mar-15, Volume: 20, Issue:6 Topics: Aminobutyrates; Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoquinolines; Male; Morphine; Motor Activity; Naloxone; Rats; Receptors, Drug; Receptors, Opioid; Substance Withdrawal Syndrome; Valerates; Valproic Acid	1977
[Effect of GABA-ergic substances on the analgesic effect of morphine in rats]. Biulleten' eksperimental'noi biologii i meditsiny, 1979, Volume: 88, Issue:7 Topics: Analgesia; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Male; Morphine; Rats; Receptors, Drug; Thiosemicarbazones; Time Factors; Valproic Acid; Vocalization, Animal	1979
Effects of gamma-aminobutyric acid and histamine on prolactin secretion in the rat. Endocrinology, 1977, Volume: 101, Issue:2 Topics: Aminobutyrates; Animals; Bicuculline; Cells, Cultured; Clonidine; Diphenhydramine; Dopamine; Drug Interactions; Estrogens; gamma-Aminobutyric Acid; Haloperidol; Histamine; Male; Morphine; Naloxone; Nerve Tissue Proteins; Phenoxybenzamine; Pituitary Gland; Progesterone; Prolactin; Rats; Thyrotropin-Releasing Hormone	1977
gamma-Aminobutyric acid receptor function in rat anterior pituitary: evidence for control of prolactin release. Endocrinology, 1979, Volume: 105, Issue:3 Topics: Animals; Apomorphine; Bicuculline; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Haloperidol; Male; Morphine; Muscimol; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Drug	1979
GABA in the ventral tegmental area: differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists. Life sciences, 1979, Oct-08, Volume: 25, Issue:15 Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Bicuculline; Carbachol; Cerebral Cortex; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Haloperidol; Humans; Isoxazoles; Male; Methyltyrosines; Morphine; Motor Activity; Muscimol; Picrotoxin; Rats; Reserpine	1979
Pharmacological manipulation of gamma-aminobutyric acid (GABA) in morphine analgesia, tolerance and physical dependence. Life sciences, 1976, May-15, Volume: 18, Issue:10 Topics: Alanine; Aminobutyrates; Aminooxyacetic Acid; Analgesia; Animals; Bicuculline; Biological Transport; Drug Interactions; Drug Tolerance; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Receptors, Drug; Substance Withdrawal Syndrome; Substance-Related Disorders	1976
Gamma-aminobutyric acid type A receptor blockade at the intermediate area of the ventral surface of the medulla counteracts the cardiorespiratory depression produced by intravenous midazolam. Pharmacology, 1992, Volume: 45, Issue:3 Topics: Animals; Bicuculline; Cardiovascular System; Cats; GABA-A Receptor Antagonists; Medulla Oblongata; Midazolam; Morphine; Naloxone; Pentobarbital; Respiratory System	1992
The isolated spinal cord-skin preparation of the newborn rat and effects of some algogenic and analgesic substances. European journal of pharmacology, 1992, Sep-22, Volume: 220, Issue:2-3 Topics: Action Potentials; Analgesics; Animals; Animals, Newborn; Bicuculline; Calcitonin Gene-Related Peptide; Capsaicin; Cerebrospinal Fluid; Enkephalin, Methionine; Morphine; Potassium Chloride; Prostaglandins E; Rats; Skin; Somatostatin; Spinal Cord; Substance P	1992
Wild running elicited by microinjections of bicuculline or morphine into the inferior colliculus of rats: lack of effect of periaqueductal gray lesions. Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:4 Topics: Animals; Behavior, Animal; Bicuculline; Inferior Colliculi; Male; Microinjections; Morphine; Motor Activity; Periaqueductal Gray; Rats; Rats, Inbred Strains	1992
gamma-Aminobutyric acid inhibits the potassium-stimulated release of somatostatin from rat spinal cord slices. Brain research, 1990, Jan-15, Volume: 507, Issue:1 Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Morphine; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord	1990
GABAA and GABAB antagonists prevent the opioid inhibition of endogenous acetylcholine release evoked by glutamate from rat neostriatal slices. Neuroscience letters, 1990, Dec-11, Volume: 120, Issue:2 Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, GABA-A	1990
Antagonism of GABAB-receptor-mediated responses in the guinea-pig isolated ileum and vas deferens by phosphono-analogues of GABA. British journal of pharmacology, 1990, Volume: 99, Issue:2 Topics: Adenosine; Animals; Bicuculline; Electric Stimulation; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Norepinephrine; Receptors, GABA-A; Structure-Activity Relationship; Vas Deferens	1990
Habenula as a relay in the descending pathway from nucleus accumbens to periaqueductal grey subserving antinociception. The International journal of neuroscience, 1990, Volume: 54, Issue:3-4 Topics: Animals; Bicuculline; Efferent Pathways; Enkephalin, Methionine; Immune Sera; Injections; Morphine; Muscimol; Naloxone; Nociceptors; Nucleus Accumbens; Periaqueductal Gray; Rabbits; Thalamic Nuclei	1990
GABAergic agents-induced antinociceptive effect in mice. Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:10 Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Mice; Morphine; Muscimol; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds; Valproic Acid	1989
Seizures evoked from area tempestas are subject to control by GABA and glutamate receptors in substantia nigra. Experimental neurology, 1989, Volume: 105, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Bicuculline; Glutamates; Male; Morphine; Muscimol; Olfactory Bulb; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Seizures; Substantia Nigra; Valine	1989
Role of GABAergic system in prolactin analgesia. Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:11 Topics: Analgesics; Animals; Bicuculline; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Morphine; Prolactin	1989
Effects of microiontophoretically-applied morphine on the Purkinje cell in the cerebellum of the cat. Neuropharmacology, 1989, Volume: 28, Issue:3 Topics: Animals; Bicuculline; Cats; Cerebellum; Female; GABA Antagonists; Iontophoresis; Male; Morphine; Naloxone; Picrotoxin; Purkinje Cells	1989
[Proconvulsant effect of morphine on seizures induced by pentylenetetrazol in the mice]. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1988, Volume: 8, Issue:3 Topics: Animals; Bicuculline; Convulsants; Drug Synergism; Male; Mice; Morphine; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A	1988
Morphine increases the activity of midbrain dopamine neurons in vitro. European journal of pharmacology, 1985, Aug-07, Volume: 114, Issue:1 Topics: Animals; beta-Endorphin; Bicuculline; Dopamine; Endorphins; Enkephalin, Leucine; In Vitro Techniques; Male; Mesencephalon; Mice; Morphine; Neurons; Substantia Nigra	1985
Infusion of opiates into substantia nigra protects against maximal electroshock seizures in rats. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:1 Topics: Animals; Bicuculline; Electroshock; Enkephalin, Methionine; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, kappa; Seizures; Substantia Nigra	1985
The role of gamma-aminobutyric acid mechanisms of the zona incerta-lateral hypothalamus in the catalepsy and muscle rigidity evoked by morphine. Brain research, 1987, Apr-07, Volume: 408, Issue:1-2 Topics: Animals; Bicuculline; Catalepsy; Hypothalamic Area, Lateral; Male; Morphine; Muscle Rigidity; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thalamic Nuclei	1987
Inhibition of baroreflex following microinjection of GABA or morphine into the nucleus tractus solitarii in rabbits. Journal of the autonomic nervous system, 1988, Volume: 25, Issue:2-3 Topics: Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Heart Rate; Histological Techniques; Male; Medulla Oblongata; Microinjections; Morphine; Naloxone; Pressoreceptors; Rabbits	1988
Reversal of the effect of centrally-administered diazepam on morphine antinociception by specific (Ro 15-1788 and Ro 15-3505) and non-specific (bicuculline and caffeine) benzodiazepine antagonists. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 333, Issue:1 Topics: Animals; Benzodiazepinones; Bicuculline; Caffeine; Diazepam; Flumazenil; Injections, Intraventricular; Male; Morphine; Pain; Rats; Rats, Inbred Strains	1986
GABAA-antagonists and baclofen analgesia. General pharmacology, 1988, Volume: 19, Issue:5 Topics: Analgesia; Animals; Baclofen; Bicuculline; GABA Antagonists; Injections, Intraperitoneal; Male; Mice; Morphine; Naloxone; Picrotoxin; Time Factors	1988
Modulation by morphine of aversive-like behavior induced by GABAergic blockade in periaqueductal gray or medial hypothalamus. Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:1 Topics: Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Escape Reaction; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Morphine; Motor Activity; Periaqueductal Gray; Rats; Rats, Inbred Strains	1988
The role of GABA in morphine abstinence in rats. Drug and alcohol dependence, 1988, Volume: 21, Issue:1 Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Male; Morphine; Rats; Rats, Inbred Strains; Serotonin; Substance Withdrawal Syndrome	1988
Restraint stress decreases afternoon plasma prolactin levels in female rats. Influence of neural antagonists and agonists on restraint-induced changes in plasma prolactin and corticosterone. Neuroendocrinology, 1986, Volume: 43, Issue:2 Topics: Animals; Arecoline; Atropine; Bicuculline; Corticosterone; Female; Injections, Intravenous; Morphine; Naloxone; Ovariectomy; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Pimozide; Prolactin; Propranolol; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological; Sympathomimetics	1986
Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission. Brain research, 1986, Nov-05, Volume: 397, Issue:1 Topics: Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Morphine; Muscimol; Neural Pathways; Pain; Pain Measurement; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains	1986
[Effect of the nitro analog of tetrapeptidamide and morphine on the cerebral blood supply]. Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:9 Topics: Animals; Bicuculline; Cats; Cerebrovascular Circulation; Enkephalins; Hemodynamics; Morphine; Nitro Compounds; Receptors, GABA-A; Reflex	1984
[Effect of diazepam on various effects of morphine use in mice and rats]. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1984, Volume: 39 Topics: Animals; Bicuculline; Diazepam; Drug Interactions; Etorphine; Male; Mice; Morphine; Motor Activity; Picrotoxin; Rats; Rats, Inbred Strains; Respiration; Synaptic Transmission	1984
Modification of the antinociceptive effect of morphine by centrally administered diazepam and midazolam. British journal of pharmacology, 1982, Volume: 75, Issue:4 Topics: Analgesics; Animals; Anti-Anxiety Agents; Benzodiazepines; Bicuculline; Diazepam; Injections, Intraventricular; Male; Midazolam; Morphine; Rats; Rats, Inbred Strains; Time Factors	1982
GABA-opiates interactions in the activity of analgesics. Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 265, Issue:1 Topics: Aminooxyacetic Acid; Analgesics, Opioid; Animals; Bicuculline; Cyclic GMP; Drug Interactions; gamma-Aminobutyric Acid; Male; Morphine; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Opioid; Structure-Activity Relationship; Valproic Acid	1983
Neurotransmitter-blocking agents influence antinociceptive effects of carbamazepine, baclofen, pentazocine and morphine on bradykinin-induced trigeminal pain. Neuropharmacology, 1984, Volume: 23, Issue:6 Topics: Analgesics; Animals; Atropine; Baclofen; Bicuculline; Bradykinin; Carbamazepine; Haloperidol; Male; Methysergide; Morphine; Naloxone; Neurotransmitter Agents; Pentazocine; Rats; Rats, Inbred Strains; Sympatholytics; Trigeminal Neuralgia; Trigeminal Nucleus, Spinal	1984
Effects of some GABA-mimetic drugs on the antinociceptive activity of morphine and beta-endorphin in rats. Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 316, Issue:3 Topics: Analgesics; Animals; beta-Endorphin; Bicuculline; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Morphine; Muscimol; Nicotinic Acids; Nipecotic Acids; Rats	1981
Dipropylacetate-induced quasi-morphine abstinence behaviour in the rat: involvement of amygdaloid and thalamic structures. Brain research, 1981, Dec-14, Volume: 229, Issue:1 Topics: Amygdala; Animals; Bicuculline; Caudate Nucleus; Hippocampus; Humans; Male; Morphine; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Opioid; Substance Withdrawal Syndrome; Substantia Nigra; Thalamic Nuclei; Valproic Acid	1981
Role of GABAergic mechanisms in the substantia nigra pars reticulata in modulating morphine-induced muscular rigidity in rats. Neuroscience letters, 1982, Jul-20, Volume: 31, Issue:1 Topics: Animals; Bicuculline; Caudate Nucleus; Dose-Response Relationship, Drug; Electromyography; Hindlimb; Male; Morphine; Muscimol; Muscle Tonus; Neural Pathways; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Substantia Nigra; Synaptic Transmission	1982
Convulsant and anticonvulsant effects of opioids: relationship to GABA-mediated transmission. Neuropharmacology, 1982, Volume: 21, Issue:10 Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Brain; Convulsants; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Morphine; Naloxone; Narcotics; Picrotoxin; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission	1982
Morphine potentiates seizures induced by GABA antagonists and attenuates seizures induced by electroshock in the rat. European journal of pharmacology, 1983, Nov-25, Volume: 95, Issue:3-4 Topics: Animals; Bicuculline; Drug Synergism; Electroshock; GABA Antagonists; Isoniazid; Male; Morphine; Naloxone; Picrotoxin; Rats; Rats, Inbred Strains; Seizures	1983
Comparison of the analgesic actions of THIP and morphine. General pharmacology, 1983, Volume: 14, Issue:6 Topics: Analgesics; Animals; Atropine; Benzoquinones; Bicuculline; Hypnotics and Sedatives; Isoxazoles; Male; Mice; Morphine; Naloxone; Oxazoles; Quinones; Reaction Time	1983
The effects of naloxone, morphine and methionine enkephalinamide on Ia afferent terminations in the cat spinal cord. Brain research, 1984, Jun-15, Volume: 303, Issue:2 Topics: Afferent Pathways; Animals; Bicuculline; Cats; Electric Stimulation; Enkephalin, Methionine; gamma-Aminobutyric Acid; Morphine; Muscles; Naloxone; Piperidines; Procaine; Reflex, Monosynaptic; Synapses	1984
The stimulus properties of gamma-hydroxybutyrate. Psychopharmacology, 1981, Volume: 73, Issue:4 Topics: Animals; Bicuculline; Conditioning, Operant; Female; Hydroxybutyrates; Lysergic Acid Diethylamide; Morphine; Naloxone; Prejudice; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Sodium Oxybate	1981
A comparison of the analgesic activities of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP) and 6-chloro-2[1-piperazinyl]pyrazine (MK 212). European journal of pharmacology, 1983, Jun-03, Volume: 90, Issue:2-3 Topics: Analgesics; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Isoxazoles; Male; Mice; Morphine; Oxazoles; Pyrazines; Time Factors	1983
GABAergic drugs, morphine and morphine tolerance: a study in relation to nociception and gastrointestinal transit in mice. Neuropharmacology, 1983, Volume: 22, Issue:6 Topics: Aminooxyacetic Acid; Analgesia; Animals; Baclofen; Bicuculline; Cyclohexanecarboxylic Acids; Digestion; Digestive System; Digestive System Physiological Phenomena; Drug Tolerance; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Morphine; Muscimol; Naloxone; Nociceptors; Oxazoles; Picrotoxin	1983
Role of GABAergic systems in the development of morphine tolerance in formalin-treated mice. Japanese journal of pharmacology, 1995, Volume: 68, Issue:2 Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Diazepam; Drug Tolerance; Flumazenil; Formaldehyde; GABA Agonists; GABA Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Muscimol; Pain; Pain Measurement; Receptors, GABA	1995
Barbiturate-reversible reduction of water diffusion coefficient in flurothyl-induced status epilepticus in rats. Magnetic resonance in medicine, 1995, Volume: 33, Issue:2 Topics: Animals; Bicuculline; Body Water; Brain; Diffusion; Dose-Response Relationship, Drug; Electroencephalography; Female; Flurothyl; Halothane; Magnetic Resonance Imaging; Morphine; Nitrous Oxide; Pentobarbital; Rats; Status Epilepticus; Time Factors	1995
Interactions between opioid drugs and propofol in laboratory models of seizures. British journal of anaesthesia, 1995, Volume: 74, Issue:3 Topics: Analgesics, Opioid; Animals; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Fentanyl; Kainic Acid; Meperidine; Mice; Mice, Inbred Strains; Morphine; N-Methylaspartate; Propofol; Seizures	1995
Direct excitatory opiate effects mediated by non-synaptic actions on rat medial vestibular neurons. European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2 Topics: Action Potentials; Animals; Bicuculline; Calcium; Enkephalin, Leucine-2-Alanine; Iontophoresis; Magnesium; Male; Morphine; Naloxone; Neurons; Rats; Rats, Wistar; Receptors, GABA; Receptors, Opioid, delta; Receptors, Opioid, mu; Synaptic Transmission; Vestibular Nuclei	1994
An ATP-sensitive potassium channel blocker abolishes the potentiating effect of morphine on the bicuculline-induced convulsion in mice. Psychopharmacology, 1993, Volume: 110, Issue:4 Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Bicuculline; Epilepsy, Tonic-Clonic; Glyburide; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Morphine; Muscimol; Potassium Channels	1993
Area tempestas modulates the behavioural responses to nociceptive stimuli in rats. Annali dell'Istituto superiore di sanita, 1993, Volume: 29, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Azocines; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Escape Reaction; Foot; Hot Temperature; Male; Morphine; Naltrexone; Narcotic Antagonists; Olfactory Pathways; Pain; Phenazocine; Pressure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Seizures; Tail	1993
Opioid and GABA modulation of accumbens-evoked ventral pallidal activity. Journal of neural transmission. General section, 1993, Volume: 93, Issue:2 Topics: Action Potentials; Animals; Bicuculline; Electric Stimulation; Electrodes; Endorphins; gamma-Aminobutyric Acid; Globus Pallidus; Iontophoresis; Male; Morphine; Naloxone; Norepinephrine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley	1993
Basal release of Met-enkephalin and neurotensin in the ventrolateral periaqueductal gray matter of the rat: a microdialysis study of antinociceptive circuits. Brain research, 1995, Sep-04, Volume: 690, Issue:2 Topics: Animals; Basal Metabolism; Bicuculline; Enkephalin, Methionine; Feedback; GABA Antagonists; Male; Microdialysis; Morphine; Neural Pathways; Neurotensin; Pain; Periaqueductal Gray; Rats; Rats, Sprague-Dawley	1995
Piracetam and aniracetam antagonism of centrally active drug-induced antinociception. Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:4 Topics: Analgesics; Analgesics, Opioid; Animals; Baclofen; Bicuculline; Male; Mice; Morphine; Nootropic Agents; Pain Measurement; Pain Threshold; Picrotoxin; Piracetam; Postural Balance; Pyrrolidinones; Receptors, GABA-B	1996
Endogenous opioid-mediated inhibition of putative pain-modulating neurons in rat rostral ventromedial medulla. Neuroscience, 1996, Volume: 74, Issue:3 Topics: Animals; Bicuculline; Brain Mapping; Enkephalins; Evoked Potentials; Male; Medulla Oblongata; Morphine; Naloxone; Nerve Endings; Neurons; Pain; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Reflex	1996
Local opioid withdrawal in rat single periaqueductal gray neurons in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Nov-15, Volume: 16, Issue:22 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Baclofen; Bicuculline; Clonidine; Drug Tolerance; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Male; Membrane Potentials; Morphine; Naloxone; Narcotic Antagonists; Neurons; Organ Culture Techniques; Periaqueductal Gray; Potassium Channels; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Substance Withdrawal Syndrome; Tetrodotoxin; Time Factors; Valine	1996
Gabapentin enhances the antinociceptive effects of spinal morphine in the rat tail-flick test. Pain, 1997, Volume: 72, Issue:3 Topics: Acetates; Amines; Analgesics; Animals; Bicuculline; Cyclohexanecarboxylic Acids; Drug Combinations; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Morphine; Movement; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Tail	1997
Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21 Topics: Afferent Pathways; Analgesics, Opioid; Animals; Behavior, Animal; Benzazepines; Bicuculline; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Injections; Injections, Intraperitoneal; Interneurons; Morphine; Motor Activity; Naloxone; Nerve Tissue Proteins; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substantia Nigra; Tegmentum Mesencephali	1997
Opioid-induced release of neurotensin in the periaqueductal gray matter of freely moving rats. Brain research, 1997, Nov-07, Volume: 774, Issue:1-2 Topics: Analgesics, Opioid; Animals; Bicuculline; Calcium; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Agonists; GABA Antagonists; Male; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Narcotics; Neurotensin; Periaqueductal Gray; Rats; Rats, Sprague-Dawley	1997
Spinal effects of bicuculline: modulation of an allodynia-like state by an A1-receptor agonist, morphine, and an NMDA-receptor antagonist. Journal of neurophysiology, 1998, Volume: 79, Issue:3 Topics: Adenosine; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Kynurenic Acid; Male; Morphine; Naloxone; Nerve Fibers; Neurons; Pain; Physical Stimulation; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Touch	1998
[The effects of flumazenil or bicuculline on the respiratory depression by morphine]. Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:4 Topics: Action Potentials; Animals; Bicuculline; Depression, Chemical; Flumazenil; GABA Antagonists; GABA Modulators; Morphine; Naloxone; Narcotic Antagonists; Phrenic Nerve; Rats; Respiration; Respiratory Insufficiency	1998
Ventrolateral periaqueductal gray matter and the control of tonic immobility. Brain research bulletin, 1999, Volume: 50, Issue:3 Topics: Animals; Bicuculline; Brain Mapping; Carbachol; Escape Reaction; Guinea Pigs; Male; Microinjections; Morphine; Muscimol; Naloxone; Neural Pathways; Periaqueductal Gray; Posture; Restraint, Physical	1999
Selective modulation of excitatory transmission by mu-opioid receptor activation in rat supraoptic neurons. Journal of neurophysiology, 1999, Volume: 82, Issue:6 Topics: Animals; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Male; Membrane Potentials; Morphine; Narcotics; Neurosecretory Systems; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, mu; Supraoptic Nucleus; Synaptic Transmission	1999
Effects of differential modulation of mu-, delta- and kappa-opioid systems on bicuculline-induced convulsions in the mouse. Brain research, 2000, Apr-17, Volume: 862, Issue:1-2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Bicuculline; Brain Chemistry; Convulsants; Enkephalin, D-Penicillamine (2,5)-; Epilepsy, Tonic-Clonic; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Quinolines; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Seizures; Synaptic Transmission	2000
Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner. Brain research. Developmental brain research, 2000, May-11, Volume: 121, Issue:1 Topics: Age Factors; Analgesics, Opioid; Animals; Bicuculline; Convulsants; Disease Susceptibility; Epilepsy; Female; gamma-Aminobutyric Acid; Male; Morphine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Seizures; Sex Factors	2000
Local opiate withdrawal in locus coeruleus neurons in vitro. Journal of neurophysiology, 2001, Volume: 85, Issue:6 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Barium; Bicuculline; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Kynurenic Acid; Locus Coeruleus; Male; Membrane Potentials; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Neurons; Ouabain; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tetrodotoxin; Thionucleotides	2001
GABA mechanisms and antinociception in mice with ligated sciatic nerve. Pharmacology & toxicology, 2001, Volume: 89, Issue:2 Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; Ligation; Male; Mice; Mice, Inbred Strains; Morphine; Muscimol; Naloxone; Organophosphorus Compounds; Pain; Pain Measurement; Sciatic Nerve	2001
Prenatal morphine exposure decreases susceptibility of adult male rat offspring to bicuculline seizures. Brain research, 2001, Dec-20, Volume: 922, Issue:2 Topics: Animals; Bicuculline; Brain; Disease Susceptibility; Epilepsy; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Morphine; Orchiectomy; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures; Sex Factors; Testosterone	2001
The effects of fruit essential oil of the Pimpinella anisum on acquisition and expression of morphine induced conditioned place preference in mice. Journal of ethnopharmacology, 2002, Volume: 80, Issue:1 Topics: Animals; Bicuculline; Conditioning, Psychological; Fruit; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Mice; Morphine; Oils, Volatile; Organophosphorus Compounds; Pimpinella; Substance-Related Disorders	2002
Effect of intracerebroventricular injection of GABA receptor agents on morphine-induced antinociception in the formalin test. Journal of psychopharmacology (Oxford, England), 2002, Volume: 16, Issue:1 Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Formaldehyde; GABA Agents; GABA Agonists; GABA Antagonists; Injections, Intraventricular; Male; Morphine; Muscimol; Organophosphorus Compounds; Pain Measurement; Rats; Receptors, GABA	2002
Intracerebroventricular morphine produces antinociception by evoking gamma-aminobutyric acid release through activation of 5-hydroxytryptamine 3 receptors in the spinal cord. Anesthesiology, 2002, Volume: 96, Issue:5 Topics: Analgesics, Opioid; Animals; Behavior, Animal; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Spinal Cord	2002
Central nucleus of the amygdala and the control of tonic immobility in guinea pigs. Brain research bulletin, 2002, Volume: 58, Issue:1 Topics: Amygdala; Animals; Bicuculline; Carbachol; Cholinergic Agonists; Fear; GABA Agonists; GABA Antagonists; Guinea Pigs; Male; Microinjections; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Narcotics; Reflex, Startle	2002
Bicuculline seizure susceptibility and nigral GABAA alpha1 receptor mRNA is altered in adult prenatally morphine-exposed females. Psychoneuroendocrinology, 2003, Volume: 28, Issue:3 Topics: Analgesics, Opioid; Animals; Bicuculline; Disease Susceptibility; Estradiol; Female; Hormone Replacement Therapy; Morphine; Ovariectomy; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Seizures; Substantia Nigra	2003
Serotonin-GABA interactions in the modulation of mu- and kappa-opioid analgesia. Neuropharmacology, 2003, Volume: 44, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Fenclonine; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Morphine; Pain Threshold; Reaction Time; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Serotonin Agents; Serotonin Antagonists	2003
Cholera toxin B decreases bicuculline seizures in prenatally morphine- and saline-exposed male rats. Pharmacology, biochemistry, and behavior, 2004, Volume: 77, Issue:3 Topics: Animals; Bicuculline; Cholera Toxin; Female; Male; Morphine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Seizures; Sodium Chloride	2004
GABA(A) receptors in the basolateral amygdala are involved in mediating morphine reward. Brain research, 2004, Apr-23, Volume: 1006, Issue:1 Topics: Amygdala; Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Morphine; Motor Activity; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Reinforcement Schedule; Reward	2004
Involvement of GABAergic modulation of the nucleus submedius (Sm) morphine-induced antinociception. Pain, 2004, Volume: 108, Issue:1-2 Topics: Analgesics, Opioid; Animals; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Nociceptors; Pain Threshold; Rats; Rats, Sprague-Dawley; Reflex; Tail; Thalamic Nuclei	2004
Defensive behaviors evoked from the ventrolateral periaqueductal gray of the rat: comparison of opioid and GABA disinhibition. Behavioural brain research, 2005, Oct-14, Volume: 164, Issue:1 Topics: Analgesics, Opioid; Animals; Bicuculline; Escape Reaction; GABA Antagonists; Immobility Response, Tonic; Male; Microinjections; Morphine; Motor Activity; Neural Inhibition; Neurons; Pain Threshold; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Reaction Time	2005
Different effects of GABAergic receptors located in the ventral tegmental area on the expression of morphine-induced conditioned place preference in rat. European journal of pharmacology, 2005, Nov-07, Volume: 524, Issue:1-3 Topics: Analgesics, Opioid; Animals; Baclofen; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Morphine; Muscimol; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Ventral Tegmental Area	2005
Effect of the GABAergic system on memory formation and state-dependent learning induced by morphine in rats. Pharmacology, 2006, Volume: 76, Issue:2 Topics: Animals; Avoidance Learning; Bicuculline; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Learning; Male; Memory; Morphine; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A	2006
Involvement of GABAergic modulation of antinociception induced by morphine microinjected into the ventrolateral orbital cortex. Brain research, 2006, Feb-16, Volume: 1073-1074 Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Microinjections; Morphine; Muscimol; Narcotics; Neurons; Nociceptors; Pain Measurement; Picrotoxin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time	2006
GABA(A) receptors of hippocampal CA1 regions are involved in the acquisition and expression of morphine-induced place preference. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2007, Volume: 17, Issue:1 Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; GABA Agonists; GABA Antagonists; Hippocampus; Male; Morphine; Motor Activity; Muscimol; Narcotics; Rats; Rats, Wistar; Receptors, GABA-A; Reinforcement, Psychology	2007
Interactions between opioid-peptides-containing pathways and GABA(A)-receptors-mediated systems modulate panic-like-induced behaviors elicited by electric and chemical stimulation of the inferior colliculus. Brain research, 2006, Aug-09, Volume: 1104, Issue:1 Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Drug Interactions; Electric Stimulation; Freezing Reaction, Cataleptic; GABA Antagonists; Inferior Colliculi; Male; Morphine; Naloxone; Narcotic Antagonists; Neural Pathways; Opioid Peptides; Pain; Rats; Rats, Wistar; Receptors, GABA-A; Stimulation, Chemical	2006
Effect of GABA receptor agonists or antagonists on morphine-induced Straub tail in mice. The International journal of neuroscience, 2006, Volume: 116, Issue:8 Topics: Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; Hindlimb Suspension; Male; Mice; Morphine; Muscimol; Narcotics; Organophosphorus Compounds; Picrotoxin	2006
[Effect of morphine on dorsal horn projection neurons in neuropathic pain rats]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2006, Volume: 31, Issue:4 Topics: Analgesics, Opioid; Animals; Bicuculline; Electrophysiology; Hyperesthesia; Male; Morphine; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Nerves	2006
Role of opioidergic and GABAergic neurotransmission of the nucleus raphe magnus in the modulation of tonic immobility in guinea pigs. Brain research bulletin, 2007, Apr-02, Volume: 72, Issue:1 Topics: Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Immobility Response, Tonic; Male; Microinjections; Models, Neurological; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Raphe Nuclei	2007
Morphine-induced sensitization in mice: changes in locomotor activity by prior scheduled exposure to GABAA receptor agents. Behavioural pharmacology, 2007, Volume: 18, Issue:4 Topics: Analysis of Variance; Animals; Bicuculline; Drug Interactions; GABA Agonists; GABA Antagonists; Male; Mice; Morphine; Motor Activity; Muscimol; Narcotics	2007
Potential roles of GABA receptors in morphine self-administration in rats. Neuroscience letters, 2007, Nov-20, Volume: 428, Issue:1 Topics: Animals; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; Male; Morphine; Morpholines; Muscimol; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, GABA; Reinforcement, Psychology; Self Administration	2007
Modulation of gamma-aminobutyric acid on painful sense in central nervous system of morphine-dependent rats. Neuroscience bulletin, 2008, Volume: 24, Issue:5 Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Drug Administration Schedule; Electric Stimulation; Female; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Morphine; Morphine Dependence; Narcotics; Nucleus Accumbens; Pain; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Time Factors	2008
Morphine increases acetylcholine release in the trigeminal nuclear complex. Sleep, 2008, Volume: 31, Issue:12 Topics: Acetylcholine; Analgesics, Opioid; Animals; Bethanechol; Bicuculline; Brain Mapping; Dose-Response Relationship, Drug; GABA Antagonists; Interneurons; Male; Microdialysis; Morphine; Muscarinic Agonists; Neural Inhibition; Rats; Rats, Wistar; Sodium Channel Blockers; Tetrodotoxin; Trigeminal Nuclei	2008
Tegmental pedunculopontine glutamate and GABA-B synapses mediate morphine reward. Behavioral neuroscience, 2009, Volume: 123, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Male; Morphine; N-Methylaspartate; Narcotics; Pedunculopontine Tegmental Nucleus; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Glutamate; Reward	2009
Glycine inhibitory dysfunction induces a selectively dynamic, morphine-resistant, and neurokinin 1 receptor- independent mechanical allodynia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Feb-25, Volume: 29, Issue:8 Topics: Analgesics, Opioid; Animals; Bicuculline; Blood Pressure; Capsaicin; Disease Models, Animal; Drug Resistance; Extracellular Signal-Regulated MAP Kinases; GABA Antagonists; Glycine; Hyperalgesia; Male; Morphine; Nonlinear Dynamics; Oncogene Proteins v-fos; Pain Measurement; Pain Threshold; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Strychnine	2009
GABA(A) receptors mediate the opposing roles of dopamine and the tegmental pedunculopontine nucleus in the motivational effects of ethanol. The European journal of neuroscience, 2009, Volume: 29, Issue:6 Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethanol; Female; Functional Laterality; GABA Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motivation; Narcotics; Pedunculopontine Tegmental Nucleus; Receptors, Dopamine D2; Receptors, GABA-A; Reinforcement, Psychology; Substance Withdrawal Syndrome; Time Factors	2009
Effects of systemic bicuculline or morphine on formalin-evoked pain-related behaviour and c-Fos expression in trigeminal nuclei after formalin injection into the lip or tongue in rats. Experimental brain research, 2009, Volume: 196, Issue:2 Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Bicuculline; Formaldehyde; GABA Antagonists; Gene Expression; Genes, fos; Lip; Male; Morphine; Neurons; Pain; Pain Measurement; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Tongue; Trigeminal Ganglion; Trigeminal Nuclei	2009
Ventral tegmental area BDNF induces an opiate-dependent-like reward state in naive rats. Science (New York, N.Y.), 2009, Jun-26, Volume: 324, Issue:5935 Topics: Animals; Bicuculline; Brain-Derived Neurotrophic Factor; Conditioning, Psychological; Dopamine; Dopamine Antagonists; Flupenthixol; GABA Agonists; GABA Antagonists; Heroin Dependence; Male; Morphine; Muscimol; Opioid-Related Disorders; Rats; Rats, Wistar; Receptors, GABA-A; Reward; RNA, Messenger; Signal Transduction; Substance Withdrawal Syndrome; Ventral Tegmental Area	2009
Acupuncture suppresses morphine self-administration through the GABA receptors. Brain research bulletin, 2010, Apr-05, Volume: 81, Issue:6 Topics: Acupuncture Therapy; Animals; Bicuculline; Feeding Behavior; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Morphine; Morpholines; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Self Administration; Time Factors	2010
Opioidergic and GABAergic mechanisms in the rostral ventromedial medulla modulate the nociceptive response of vocalization in guinea pigs. Brain research bulletin, 2010, May-31, Volume: 82, Issue:3-4 Topics: Analgesics, Opioid; Animals; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Medulla Oblongata; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Vocalization, Animal	2010
Role of the central amygdala GABA-A receptors in morphine state-dependent memory. Life sciences, 2010, Jun-05, Volume: 86, Issue:23-24 Topics: Amygdala; Animals; Avoidance Learning; Bicuculline; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Memory; Morphine; Morphine Dependence; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Retention, Psychology	2010
GABAA receptors in VTA mediate the morphine-induced release of ascorbic acid in rat nucleus accumbens. Brain research, 2011, Jan-12, Volume: 1368 Topics: Analgesics, Opioid; Animals; Ascorbic Acid; Bicuculline; Chromatography, High Pressure Liquid; Dopamine; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Morphine; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Ventral Tegmental Area	2011
Protective role of taurine against morphine-induced neurotoxicity in C6 cells via inhibition of oxidative stress. Neurotoxicity research, 2011, Volume: 20, Issue:4 Topics: Analysis of Variance; Animals; Apoptosis; Bicuculline; Caspase 3; Catalase; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Flow Cytometry; GABA-A Receptor Antagonists; Gene Expression Regulation, Neoplastic; Glioma; Glutathione Peroxidase; Morphine; Narcotics; Oxidative Stress; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Superoxide Dismutase; Taurine; Time Factors	2011
Effect of acupuncture on naloxone-precipitated withdrawal syndrome in morphine-experienced rats: the mediation of GABA receptors. Neuroscience letters, 2011, Oct-31, Volume: 504, Issue:3 Topics: Acupuncture Points; Acupuncture Therapy; Animals; Bicuculline; Diarrhea; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Morphine; Morphine Dependence; Morpholines; Muscle Contraction; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Substance Withdrawal Syndrome; Tremor	2011
The effects of hippocampal opioidergic and septal GABAergic system interactions on anxiety-like behavior in rats. Life sciences, 2011, Nov-21, Volume: 89, Issue:21-22 Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; CA1 Region, Hippocampal; GABA Agonists; GABA Antagonists; Hippocampus; Male; Microinjections; Morphine; Muscimol; Narcotics; Rats; Rats, Wistar; Receptors, GABA; Receptors, Opioid, mu; Septum of Brain	2011
Opioidergic, GABAergic and serotonergic neurotransmission in the dorsal raphe nucleus modulates tonic immobility in guinea pigs. Physiology & behavior, 2012, May-15, Volume: 106, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Bicuculline; Drug Interactions; GABAergic Neurons; Guinea Pigs; Immobility Response, Tonic; Male; Microinjections; Morphine; Muscimol; Naloxone; Opioid Peptides; Raphe Nuclei; Serotonergic Neurons; Serotonin; Serotonin 5-HT2 Receptor Agonists; Synaptic Transmission	2012
Reversal of morphine analgesic tolerance by ethanol in the mouse. The Journal of pharmacology and experimental therapeutics, 2013, Volume: 345, Issue:3 Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Central Nervous System Depressants; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ethanol; GABA Antagonists; Hypnotics and Sedatives; Immersion; Injections, Intraventricular; Male; Mice; Morphine; Pain Measurement; Receptors, GABA-A; Receptors, GABA-B	2013
GABA increases stimulus selectivity of neurons in primary visual cortices of cats chronically treated with morphine. Neuroscience, 2013, Jun-25, Volume: 241 Topics: Animals; Bicuculline; Cats; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Morphine; Narcotics; Neurons; Photic Stimulation; Visual Cortex	2013
Role of GABAA receptors in dorsal raphe nucleus in stress-induced reinstatement of morphine-conditioned place preference in rats. Psychopharmacology, 2013, Volume: 230, Issue:4 Topics: Animals; Behavior, Animal; Bicuculline; Conditioning, Psychological; Extinction, Psychological; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Morphine; Muscimol; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Serotonin; Stress, Psychological	2013
Contribution of adenylyl cyclase modulation of pre- and postsynaptic GABA neurotransmission to morphine antinociception and tolerance. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:9 Topics: Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics, Opioid; Animals; Bicuculline; Colforsin; Drug Tolerance; Enzyme Activators; Enzyme Inhibitors; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Miniature Postsynaptic Potentials; Morphine; Nociception; Presynaptic Terminals; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission	2014
Nociceptive vocalization response in guinea pigs modulated by opioidergic, GABAergic and serotonergic neurotransmission in the dorsal raphe nucleus. Brain research bulletin, 2014, Volume: 106 Topics: Analgesics, Opioid; Animals; Bicuculline; Dorsal Raphe Nucleus; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Nociception; Serotonin; Synaptic Transmission; Vocalization, Animal	2014
Acupuncture at HT7 suppresses morphine self-administration at high dose through GABA system. Neuroscience letters, 2014, Jul-25, Volume: 576 Topics: Acupuncture Points; Animals; Bicuculline; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Morphine; Morphine Dependence; Morpholines; Motor Activity; Narcotics; Neurons; Rats, Sprague-Dawley; Receptors, GABA; Self Administration	2014
Uridine decreases morphine-induced behavioral sensitization by decreasing dorsal striatal dopamine release possibly via agonistic effects at GABAA receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:9 Topics: Analgesics, Opioid; Animals; Animals, Inbred Strains; beta-Alanine; Bicuculline; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Mice; Morphine; Motor Activity; Receptors, GABA-A; Time Factors; Uracil; Uridine	2014
The Pronociceptive Effect of Paradoxical Sleep Deprivation in Rats: Evidence for a Role of Descending Pain Modulation Mechanisms. Molecular neurobiology, 2016, Volume: 53, Issue:3 Topics: Animals; Bicuculline; Lidocaine; Male; Morphine; Motor Activity; Nociception; Pain; Pain Measurement; Periaqueductal Gray; Proto-Oncogene Proteins c-fos; Rats, Wistar; Sleep Deprivation	2016
The blockade of GABAA receptors attenuates the inhibitory effect of orexin type 1 receptors antagonist on morphine withdrawal syndrome in rats. Neuroscience letters, 2016, Mar-23, Volume: 617 Topics: Animals; Benzoxazoles; Bicuculline; GABA-A Receptor Antagonists; Locus Coeruleus; Male; Microinjections; Morphine; Naloxone; Naphthyridines; Narcotic Antagonists; Orexin Receptor Antagonists; Orexin Receptors; Rats, Wistar; Substance Withdrawal Syndrome; Urea	2016
The major neurotransmitter systems in the basolateral amygdala and the ventral tegmental area mediate morphine-induced memory consolidation impairment. Neuroscience, 2017, 06-14, Volume: 353 Topics: Amnesia; Analgesics, Opioid; Animals; Arachidonic Acids; Avoidance Learning; Basolateral Nuclear Complex; Bicuculline; Excitatory Amino Acid Agonists; GABA-A Receptor Antagonists; Male; Memory Consolidation; Morphine; N-Methylaspartate; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area	2017
Decrease of inhibitory synaptic currents of locus coeruleus neurons via orexin type 1 receptors in the context of naloxone-induced morphine withdrawal. The journal of physiological sciences : JPS, 2019, Volume: 69, Issue:2 Topics: Analgesics, Opioid; Animals; Bicuculline; GABAergic Neurons; Locus Coeruleus; Male; Morphine; Naloxone; Narcotic Antagonists; Neurons; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Synaptic Potentials; Synaptic Transmission	2019
Involvement of GABAA receptors of lateral habenula in the acquisition and expression phases of morphine-induced place preference in male rats. Behavioural pharmacology, 2022, 10-01, Volume: 33, Issue:7 Topics: Animals; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Habenula; Male; Morphine; Muscimol; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A	2022