bicuculline has been researched along with levodopa in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Bartholini, G | 1 |
| Battista, AF; Goldstein, M; Miyamoto, T | 1 |
| Persson, B; Rubenson, A; Sillén, U | 2 |
| Grahame-Smith, DG; Green, AR; Nutt, DJ | 1 |
| Amabeoku, G; Chikuni, O | 1 |
| Goshima, Y; Honjo, K; Misu, Y; Miyamae, T | 2 |
| Akbar, M; Ishihara, K; Misu, Y; Sasa, M | 1 |
| Aziz, TZ; Giladi, N; Nandi, D; Stein, JF; Winter, J | 1 |
| Aziz, TZ; Jenkinson, N; Nandi, D; Stein, JF | 1 |
| Marti, M; Morari, M; Trapella, C; Viaro, R | 1 |
| Franchi, G; Morari, M; Viaro, R | 1 |
1 trial(s) available for bicuculline and levodopa
| Article | Year |
|---|---|
Laboratory and clinical investigations of the region of the rostral brainstem in motor control.
Topics: Animals; Antiparkinson Agents; Bicuculline; Deep Brain Stimulation; Dose-Response Relationship, Radiation; Female; GABA Antagonists; Humans; Levodopa; Macaca mulatta; Male; Motor Activity; Parkinson Disease; Parkinsonian Disorders; Pedunculopontine Tegmental Nucleus; Retrospective Studies | 2006 |
13 other study(ies) available for bicuculline and levodopa
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
[Potential therapeutic activity of GABA-mimetic drugs in neuropsychiatry].
Topics: 4-Aminobutyrate Transaminase; Basal Ganglia Diseases; Bicuculline; Dopamine; Dyskinesia, Drug-Induced; Epilepsy; Extrapyramidal Tracts; gamma-Aminobutyric Acid; Humans; Huntington Disease; Levodopa; Limbic System; Neural Pathways; Neurons; Neurotransmitter Agents; Parkinson Disease; Psychopharmacology | 1979 |
Modification of involuntary movements by centrally acting drugs.
Topics: Aminooxyacetic Acid; Animals; Atropine; Bicuculline; Bromocriptine; Dopamine; Haloperidol; Haplorhini; Levodopa; Movement Disorders; Physostigmine; Picrotoxin; Piperazines; Piribedil; Receptors, Drug; Synaptic Transmission; Thalamic Nuclei; Theophylline | 1975 |
Central effects of baclofen on the L-dopa induced hyperactive urinary bladder of the rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Injections, Intraventricular; Levodopa; Male; Naloxone; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1985 |
Involvement of central GABA receptors in the regulation of the urinary bladder function of anaesthetized rats.
Topics: Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Glycine; Levodopa; Male; Muscimol; Muscle Contraction; Rats; Receptors, Cell Surface; Urinary Bladder | 1980 |
Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions--I. The effects of single and repeated bicuculline-induced seizures.
Topics: Animals; Behavior, Animal; Bicuculline; Dopamine; Levodopa; Male; Rats; Seizures; Serotonin; Time Factors; Tranylcypromine | 1980 |
GABAergic and dopaminergic systems may be involved in seizures induced by pyrimethamine in mice.
Topics: Animals; Bicuculline; Diazepam; Dopamine; Drug Interactions; gamma-Aminobutyric Acid; Levodopa; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Pyrimethamine; Seizures | 1994 |
GABA may function tonically via GABA(A) receptors to inhibit hypotension and bradycardia by L-DOPA microinjected into depressor sites of the nucleus tractus solitarii in anesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; Binding, Competitive; Bradycardia; Dopamine Agents; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Hypotension; Levodopa; Male; Microinjections; Nipecotic Acids; Pressoreceptors; Proline; Rats; Rats, Wistar; Receptors, GABA-A; Solitary Nucleus; Tritium | 1999 |
The evidence for tonic GABAergic regulation of basal L-DOPA release via activation of inhibitory GABA(A) receptors in the nucleus tractus solitarii of anesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Levodopa; Male; Microdialysis; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Solitary Nucleus | 1999 |
Inhibition by L-3,4-dihydroxyphenylalanine of hippocampal CA1 neurons with facilitation of noradrenaline and gamma-aminobutyric acid release.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Bicuculline; Dopamine Agents; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Levodopa; Male; Neurons; Norepinephrine; Phentolamine; Rats; Rats, Wistar | 2001 |
Reversal of akinesia in experimental parkinsonism by GABA antagonist microinjections in the pedunculopontine nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Bicuculline; Cholinergic Fibers; Female; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Levodopa; Macaca mulatta; Male; Motor Activity; Neural Inhibition; Neural Pathways; Parkinsonian Disorders; Pons; Receptors, GABA-A; Recovery of Function; Tegmentum Mesencephali; Treatment Outcome | 2002 |
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway.
Topics: Animals; Antiparkinson Agents; Benzimidazoles; Bicuculline; Drug Synergism; Drug Therapy, Combination; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Injections; Levodopa; Male; Microdialysis; Motor Activity; Neural Pathways; Nociceptin Receptor; Oxidopamine; Parkinsonian Disorders; Perfusion; Piperidines; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium Channel Blockers; Stereotaxic Techniques; Substantia Nigra; Tetrodotoxin; Thalamus | 2007 |
Progressive motor cortex functional reorganization following 6-hydroxydopamine lesioning in rats.
Topics: Animals; Behavior, Animal; Bicuculline; Denervation; Dopamine Agents; Electric Stimulation; GABA Antagonists; Immunohistochemistry; Levodopa; Lidocaine; Male; Motor Activity; Motor Cortex; Oxidopamine; Postural Balance; Rats; Rats, Wistar; Receptors, GABA-A; Sodium Channel Blockers; Sympatholytics; Tyrosine 3-Monooxygenase | 2011 |