bicuculline has been researched along with kainic acid in 162 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (22.22) | 18.7374 |
| 1990's | 70 (43.21) | 18.2507 |
| 2000's | 43 (26.54) | 29.6817 |
| 2010's | 10 (6.17) | 24.3611 |
| 2020's | 3 (1.85) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Di Chiara, G; Gessa, GL; Morelli, M; Mulas, ML; Porceddu, ML | 1 |
| Bronstein, JM; Dwyer, BE; Morin, AM; Sankar, R; Wasterlain, CG | 1 |
| Dasheiff, RM; Sacks, DS | 2 |
| Asprodini, EK; Rainnie, DG; Shinnick-Gallagher, P | 1 |
| Berger, T; Kettenmann, H; Schnitzer, J; Walz, W | 1 |
| Clark, B; Mobbs, P | 1 |
| Gale, K; Miller, LP; Murray, TF; Zhong, P | 1 |
| Masuda, N; Ootsuka, Y; Terui, N | 1 |
| Dudek, FE; Meier, CL; Obenaus, A | 1 |
| Cronin, J; Dudek, FE; Houser, CR; Obenaus, A | 1 |
| Cubells, JF; Makman, MH; Ndubuka, C | 1 |
| Gale, K; Maggio, R; Sohn, E | 1 |
| Bieger, D; Wang, YT | 1 |
| Smith, SS | 1 |
| DiMicco, JA; Soltis, RP | 1 |
| Armstrong, CM; Konnerth, A; Llano, I; Marty, A | 1 |
| Simpson, LH; Wheal, HV; Williamson, R | 1 |
| Bagust, J; Gardner, CR; Hussain, S; Walker, RJ | 1 |
| Besson, MJ; Gauchy, C; Lantin le Boulch, N; Truong-Ngoc, NA | 1 |
| Lok, SY; Meldrum, BS; Millan, MH; Obrenovitch, TP; Sarna, GS; Symon, L | 1 |
| Jope, RS; Ormandy, GC; Song, L | 1 |
| Gatti, PJ; Gillis, RA | 1 |
| Grantyn, R; Perouansky, M | 1 |
| Gale, K; Liminga, U; Maggio, R | 1 |
| Gale, K; Graham, J; Wardas, J | 1 |
| Paton, JF; Silva-Carvalho, L; Spyer, KM; Thompson, CS | 1 |
| Jackson, H; Parks, TN | 1 |
| Albertson, TE; Joy, RM | 1 |
| Aanonsen, LM; Wilcox, GL | 1 |
| Dasheiff, RM | 1 |
| Brandão, ML; Coimbra, NC; Leão-Borges, PC | 1 |
| Chapman, AG | 1 |
| Evans, RH | 1 |
| Gale, K; Piredda, S | 1 |
| Burton, NR; Smith, DA; Stone, TW | 1 |
| Hagberg, H; Hamberger, A; Jacobson, I; Lehmann, A | 1 |
| Breese, GR; Frye, GD; McCown, TJ; Peterson, SL | 1 |
| Armstrong, DR; Ault, B; Gruenthal, M; Nadler, JV; Wang, CM | 1 |
| DiMicco, JA; Sample, RH | 1 |
| Naquet, R; Pinard, E; Riche, D; Rigaud, AS; Seylaz, J | 1 |
| Hagberg, H; Hamberger, A; Jacobson, I; Lazarewicz, JW; Lehmann, A | 1 |
| Ferrendelli, JA; Mirski, MA | 1 |
| Armstrong, DR; Ault, B; Gruenthal, M; Nadler, JV | 1 |
| Goping, G; Klatzo, I; Nitsch, C | 1 |
| Armstrong, DR; Ault, B; Gruenthal, M; Nadler, JV; Okazaki, MM | 1 |
| Kato, S; Negishi, K; Teranishi, T | 1 |
| Kilpatrick, IC; Starr, MS; Summerhayes, M | 1 |
| Blaker, WD | 1 |
| Fujiwara, K; Klatzo, I; Nitsch, C; Suzuki, R | 1 |
| Deschênes, M; Domich, L; Mulle, C; Steriade, M | 1 |
| Aihara, H; Kurachi, M; Yoshihara, K | 1 |
| Chapman, AG; Meldrum, BS; Premachandra, M; Westerberg, E | 1 |
| Bloch, R; Bousquet, P; Feldman, J; Schwartz, J | 1 |
| Di Chiara, G; Diana, M; Imperato, A; Nicoletti, F; Scapagnini, U | 1 |
| Evans, MC; Meldrum, BS | 1 |
| Brunello, N; Cheney, DL | 1 |
| Meldrum, BS | 1 |
| Ben-Ari, Y; Meldrum, B; Naquet, R | 1 |
| Ben-Ari, Y; Charton, G; Riche, D; Tremblay, E | 1 |
| Ben-Ari, Y; Ghilini, G; Naquet, R; Riche, D; Tremblay, E | 1 |
| Lloyd, KG; Willigens, MT; Worms, P | 1 |
| Javid, MJ; Stone, WE | 1 |
| Davis, W; Penix, LP; Subramaniam, S | 1 |
| Baraban, SC; Hochman, DW; Owens, JW; Schwartzkroin, PA | 1 |
| de Feo, MR; Mecarelli, O; Ricci, GF | 1 |
| Catt, KJ; Krsmanovic, LZ; Spergel, DJ; Stojilkovic, SS | 1 |
| De Novellis, V; DiMicco, JA; Morin, SM; Rossi, F; Stotz-Potter, EH | 1 |
| Dunham, L; Guillet, R | 1 |
| Lemaire, S; Shukla, VK | 1 |
| Ahmad, I; Pleuvry, BJ | 1 |
| Anderson, DR; Martin, LP; Tepper, JM | 1 |
| Shimosaka, S; Simon, RP; So, YT | 1 |
| Czachurski, J; Doutheil, J; Seller, H; Zanzinger, J | 1 |
| Cunningham, JR; Neal, MJ; Paterson, SJ | 1 |
| Ben-Ari, Y; Gaiarsa, JL; Zagrean, L | 1 |
| Ahmad, I; Lauretti, GR; Pleuvry, BJ | 1 |
| Sowell, KL; Stringer, JL | 1 |
| Brandão, ML; Coimbra, NC | 1 |
| Blisard, KS; Fagin, K; Falivena, P; Harrington, DA; Olejniczak, P; Privitera, MD; Scremin, OU; Taylor, KL | 1 |
| Bloms-Funke, P; Madeja, M; Musshoff, U; Speckmann, EJ | 1 |
| Dong, CJ; Picaud, SA; Werblin, FS | 1 |
| Ben-Ari, Y; Khrestchatisky, M; Massamiri, T | 1 |
| Narita, K; Nishihara, M; Takahashi, M; Yokawa, T | 1 |
| Adams, JM; Allen, AM; Guyenet, PG | 1 |
| Belluardo, N; Condorelli, DF; Dell'Albani, P; Funakoshi, H; Jiang, XH; Metsis, M; Mudò, G; Salin, T; Timmusk, T | 1 |
| Davey, PG; Halliwell, RF; Lambert, JJ | 1 |
| Dudek, FE; Meier, CL | 1 |
| Czuczwar, SJ; Dzieciuch, J; Kleinrok, Z; Klonowski, P; Tutka, P | 1 |
| Corrèges, P; Duport, S; Stoppini, L | 1 |
| Feigenspan, A; Gustincich, S; Koopman, LJ; Raviola, E; Wu, DK | 1 |
| Kondoh, T; Matsuoka, T; Nishizaki, T; Tamaki, N | 1 |
| Herreras, O; Lerma, J; Rodríguez-Moreno, A | 1 |
| Isa, T; Itazawa, SI; Ozawa, S | 1 |
| Dudek, FE; Patrylo, PR | 1 |
| Budai, D; Fields, HL | 1 |
| Alzheimer, C; Chesi, AJ; Rucker, F; ten Bruggencate, G; Tretter, Y | 1 |
| Deb, S; Gottschall, PE; Zhang, JW | 1 |
| Abrahám, I; Haller, J; Juhász, G; Kruk, MR; Makara, GB; Zelena, D | 1 |
| Balestra, M; Borrelli, AR; Cramer, CL; Eismann, MS; Freedman, LR; Hudzik, TJ; Knowles, MK; Mahmood, N; McCarthy, DJ; Murray, RJ; Palmer, GC; Stagnitto, ML | 1 |
| Beaulieu, C; Lacaille, JC; Morin, F | 1 |
| Molnár, P; Nadler, JV; Okazaki, MM | 1 |
| Matsuoka, T; Matsuyama, S; Nishizaki, T; Nomura, T; Shiotani, T; Watabe, S; Yoshii, M | 1 |
| Conti, M; De Luigi, A; De Simoni, MG; Marchesi, F; Moneta, D; Ravizza, T; Vezzani, A | 1 |
| Dudek, FE; Patrylo, PR; Schweitzer, JS | 1 |
| Chen, Q; Hardy, K; Moulder, K; Olney, JW; Romano, C; Tenkova, T | 1 |
| Lerma, J; López-García, JC; Rodríguez-Moreno, A | 1 |
| Lynch, M; Sutula, T | 1 |
| Carlson, GC; Keller, A; Shipley, MT | 1 |
| Boehrer, A; Marescaux, C; Reibel, S; Simler, S; Vergnes, M | 1 |
| Cole, TB; Palmiter, RD; Robbins, CA; Schwartzkroin, PA; Wenzel, HJ | 1 |
| Stringer, JL; Xiong, ZQ | 1 |
| Jimbo, Y; Robinson, HP | 1 |
| Aden, U; Berman, RF; Fredholm, BB; O'Connor, WT | 1 |
| Hu, HJ; Pan, ZH | 1 |
| Bailey, TW; Dimicco, JA | 1 |
| Crochet, S; Sakai, K | 1 |
| Cravo, SL; Lopes, OU; Possas, OS | 1 |
| Dudek, FE; Wuarin, JP | 1 |
| Bradley, SR; Conn, PJ; Marino, MJ; Wittmann, M | 1 |
| Leung, LS; Wu, K | 2 |
| Cepeda, C; Hurst, RS; Levine, MS; Shumate, LW | 1 |
| Higgs, MH; Lukasiewicz, PD; Olney, JW; Romano, C; Salvay, D; Shen, DW | 1 |
| Dudek, FE; Smith, BN | 1 |
| Aguilar, E; González, LC; Pinilla, L; Tena-Sempere, M | 1 |
| Berkovic, SF; Clark, M; Drago, J; Finkelstein, DI; Horne, MK; Massalas, JS; McColl, C; Powney, E; Ross, SA; Wong, JY | 1 |
| Barbagli, B; Boissard, R; Fort, P; Gervasoni, D; Luppi, PH; Schmidt, MH | 1 |
| Mistlberger, RE; Pollock, MS | 1 |
| Clement, AB; Cravatt, BF; Hawkins, EG; Lichtman, AH | 1 |
| Habaguchi, T; Ohtinata-Sugimoto, J; Saitoh, K; Sakamoto, T; Takakusaki, K | 1 |
| Lasater, EM; Vigh, J | 1 |
| Anderson, AE; Johnston, D; Leung, V; Lin, X; Shah, MM | 1 |
| Henley, JM; Martin, S | 1 |
| Dudek, FE; Shao, LR | 1 |
| Henderson, Z; Jones, GA | 1 |
| Chen, L; Sokabe, M | 1 |
| Chergui, K; Greengard, P; Svenningsson, P | 1 |
| Coons, S; Ellsworth, K; Johnson, E; Kerrigan, JF; Kim, DY; Lue, LF; Nowak, L; Rekate, H; Rho, JM; St John, PA; Wu, J; Xu, L | 1 |
| Rokyta, R; Slamberová, R | 1 |
| Frotscher, M; Harvey, BD; Sloviter, RS; Zappone, CA | 1 |
| Ariwodola, OJ; Crowder, TL; Weiner, JL | 1 |
| Galanopoulou, AS | 1 |
| Akaike, A; Hama, Y; Katsuki, H; Kume, T; Suminaka, C | 1 |
| Hara, A; Murashita, H; Sakai, S; Tabuchi, K | 1 |
| Ben-Ari, Y; Khalilov, I; Nardou, R | 1 |
| DeSilva, TM; Goldhoff, PE; Kabakov, AY; Rosenberg, PA; Volpe, JJ | 1 |
| Bobeck, EN; McNeal, AL; Morgan, MM | 1 |
| Baldwin, RA; Jäger, AK; Niquet, J; Pedersen, ME; Stafford, GI; van Staden, J; Wasterlain, CG | 1 |
| Paz, C; Retana-Márquez, S; Rubio, C; Rubio-Osornio, M; Verónica Custodio, ML | 1 |
| Beleboni, RO; Cunha, AO; dos Santos, WF; Fachim, HA; Faggion, SA; Gavin, AS; Pereira, AM | 1 |
| Bird, A; Cobb, SR; Ganley, R; McLeod, F; Selfridge, J; Williams, L | 1 |
| Bazan, N; Lu, Y; Pei, L; Shang, Y; Tian, Q; Wang, X; Wen, R; Yang, Y; Zhao, K; Zhu, LQ | 1 |
| Bajrektarevic, D; Nistri, A | 1 |
| Matthiesen, M; Spiacci, A; Zangrossi, H | 1 |
| Magagna-Poveda, A; Moretto, JN; Scharfman, HE | 1 |
| Gaidin, SG; Kosenkov, AM; Maiorov, SA; Sergeev, AI; Teplov, IY; Zinchenko, VP | 1 |
| Bading, H; Bas-Orth, C; Buchthal, B; Koch, M; Lau, D | 1 |
| Ayata, C; Chung, DY; de Morais, AL; Endres, M; Loonen, ICM; Misra, A; Qin, T; Schiff, SJ; Schlunk, F; Tamim, I | 1 |
| Ávalos-Fuentes, JA; Cortés, H; Florán, B; González-Hernández, AV; Leyva-Gómez, G; Paz-Bermúdez, FJ; Recillas-Morales, S; Sánchez-Zavaleta, R | 1 |
2 review(s) available for bicuculline and kainic acid
| Article | Year |
|---|---|
Pharmacology of amino acid receptors on vertebrate primary afferent nerve fibres.
Topics: Animals; Baclofen; Barbiturates; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Kainic Acid; Neurons, Afferent; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship | 1986 |
In vivo experimental models of epilepsy.
Topics: Aluminum Hydroxide; Animals; Bicuculline; Cobalt; Convulsants; Disease Models, Animal; Electroshock; Epilepsy; Epilepsy, Reflex; Flurothyl; gamma-Aminobutyric Acid; Humans; Kainic Acid; Kindling, Neurologic; Muscarinic Agonists; Papio; Penicillins; Pentylenetetrazole; Pilocarpine; Tetanus Toxin; Zinc Compounds | 2010 |
160 other study(ies) available for bicuculline and kainic acid
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Substantia nigra as an out-put station for striatal dopaminergic responses: role of a GABA-mediated inhibition of pars reticulata neurons.
Topics: Animals; Apomorphine; Bicuculline; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Humans; Hydroxydopamines; Kainic Acid; Male; Neurons; Picrotoxin; Rats; Stereotyped Behavior; Substantia Nigra | 1979 |
Translocation and autophosphorylation of brain calmodulin kinase II in status epilepticus.
Topics: Animals; Bicuculline; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cerebral Cortex; Hippocampus; Kainic Acid; Kindling, Neurologic; Male; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley; Status Epilepticus; Translocation, Genetic | 1992 |
Seizure circuit analysis with voltage sensitive dye.
Topics: Animals; Bicuculline; Blood Pressure; Blood-Brain Barrier; Brain; Brain Mapping; Disease Models, Animal; Fluorescent Dyes; Kainic Acid; Limbic System; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley; Seizures | 1992 |
Kindling-induced long-lasting changes in synaptic transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Animals; Bicuculline; Electric Stimulation; Kainic Acid; Kindling, Neurologic; Male; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Synaptic Transmission | 1992 |
GABA- and glutamate-activated currents in glial cells of the mouse corpus callosum slice.
Topics: Action Potentials; Animals; Bicuculline; Chloride Channels; Corpus Callosum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channel Gating; Kainic Acid; Membrane Proteins; Mice; Muscimol; Oligodendroglia; Pentobarbital; Potassium Channels; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Stem Cells | 1992 |
Transmitter-operated channels in rabbit retinal astrocytes studied in situ by whole-cell patch clamping.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Bicuculline; Chloride Channels; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; Membrane Proteins; Quisqualic Acid; Rabbits; Receptors, GABA-A; Retina; Time Factors | 1992 |
Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Amygdala; Animals; Bicuculline; Brain Mapping; Carbachol; Dominance, Cerebral; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Ibotenic Acid; Kainic Acid; Limbic System; Muscimol; Quisqualic Acid; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1992 |
Neurons in the caudal ventrolateral medulla mediate the somato-sympathetic inhibitory reflex response via GABA receptors in the rostral ventrolateral medulla.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Female; gamma-Aminobutyric Acid; Kainic Acid; Kynurenic Acid; Male; Medulla Oblongata; Neurons; Neurons, Afferent; Rabbits | 1992 |
In vivo mapping of drug-induced seizures with voltage-sensitive dye.
Topics: Animals; Autoradiography; Bicuculline; Blood Pressure; Brain; Brain Mapping; Coloring Agents; Deoxyglucose; Electric Stimulation; Kainic Acid; Male; Membrane Potentials; Models, Neurological; Neural Pathways; Neuroglia; Neurons; Rats; Rats, Sprague-Dawley; Seizures | 1992 |
Persistent hyperexcitability in isolated hippocampal CA1 of kainate-lesioned rats.
Topics: Animals; Behavior, Animal; Bicuculline; Electric Stimulation; Electrophysiology; Evoked Potentials; Hippocampus; In Vitro Techniques; Injections; Kainic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Seizures | 1992 |
Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fibers.
Topics: Action Potentials; Animals; Bicuculline; Electric Stimulation; Electrophysiology; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; Nerve Fibers; Rats; Rats, Inbred Strains; Synapses | 1992 |
2-amino-4-phosphonobutyric acid exerts a light-dependent effect on post-gabaculine levels of retinal gamma-aminobutyric acid (GABA): evidence that ON synaptic pathways regulate retinal GABAergic transmission.
Topics: Aminobutyrates; Animals; Bicuculline; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Kainic Acid; Light; Male; Muscimol; Neural Pathways; Rats; Rats, Inbred Strains; Retina; Synapses; Synaptic Transmission; Veratridine | 1991 |
Lack of proconvulsant action of GABA depletion in substantia nigra in several seizure models.
Topics: Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; Isoniazid; Kainic Acid; Male; Microinjections; Muscimol; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Synaptic Transmission | 1991 |
Role of solitarial GABAergic mechanisms in control of swallowing.
Topics: Animals; Bicuculline; Deglutition; Electric Stimulation; Esophagus; Kainic Acid; Male; Medulla Oblongata; Models, Biological; Muscarine; Muscimol; Pharynx; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Muscarinic | 1991 |
Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells.
Topics: Amino Acids; Animals; Bicuculline; Cerebellum; Drug Synergism; Electrophysiology; Female; Kainic Acid; N-Methylaspartate; Progesterone; Purkinje Cells; Quisqualic Acid; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1991 |
GABAA and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kainic Acid; Male; Microinjections; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1991 |
Synaptic- and agonist-induced excitatory currents of Purkinje cells in rat cerebellar slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Electric Stimulation; Glutamates; Kainic Acid; Membrane Potentials; Piperazines; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
The contribution of non-NMDA and NMDA receptors to graded bursting activity in the CA1 region of the hippocampus in a chronic model of epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Chronic Disease; Electric Stimulation; Electrophysiology; Epilepsy; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Receptor sub-types involved in responses of Purkinje cell to exogenous excitatory amino acids and local electrical stimulation in cerebellar slices in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cerebellum; Electric Stimulation; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
In vivo release of newly synthesized [3H]GABA in the substantia nigra of the rat: relative contribution of GABA striato-pallido-nigral afferents and nigral GABA neurons.
Topics: Anesthesia; Animals; Bicuculline; Calcium; Corpus Striatum; gamma-Aminobutyric Acid; Globus Pallidus; Glutamine; Glycine; Kainic Acid; Ketamine; Male; Nerve Endings; Neurons; Neurons, Afferent; Potassium; Rats; Rats, Inbred Strains; Stereotaxic Techniques; Substantia Nigra | 1991 |
Changes in rat brain extracellular glutamate concentration during seizures induced by systemic picrotoxin or focal bicuculline injection: an in vivo dialysis study with on-line enzymatic detection.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicuculline; Brain Chemistry; Cerebral Cortex; Dialysis; Electroencephalography; Electroshock; Extracellular Space; Glutamates; Hippocampus; Injections; Kainic Acid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1991 |
Analysis of the convulsant-potentiating effects of lithium in rats.
Topics: Animals; Bicuculline; Chlorides; Convulsants; Drug Synergism; Hippocampus; Kainic Acid; Lithium; Lithium Chloride; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Inbred Strains; Seizures | 1991 |
Interaction between pressor and depressor areas in cat ventrolateral medulla.
Topics: Animals; Bicuculline; Blood Pressure; Cats; Female; gamma-Aminobutyric Acid; Kainic Acid; Male; Medulla Oblongata; Models, Neurological; Organ Specificity; Picrotoxin; Strychnine; Time Factors | 1991 |
Is GABA release modulated by presynaptic excitatory amino acid receptors?
Topics: Action Potentials; Animals; Bicuculline; Cells, Cultured; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Superior Colliculi | 1990 |
Selective stimulation of kainate but not quisqualate or NMDA receptors in substantia nigra evokes limbic motor seizures.
Topics: Animals; Bicuculline; Convulsants; Electroencephalography; Injections; Kainic Acid; Limbic System; Male; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Substantia Nigra | 1990 |
Evidence for a role of glycine in area tempestas for triggering convulsive seizures.
Topics: Animals; Anticonvulsants; Bicuculline; Carbachol; Cerebral Cortex; Glycine; Kainic Acid; Kynurenic Acid; Male; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1990 |
Nucleus tractus solitarius as mediator of evoked parabrachial cardiovascular responses in the decerebrate rabbit.
Topics: Animals; Bicuculline; Decerebrate State; Electric Stimulation; Evoked Potentials; Hemodynamics; Kainic Acid; Medulla Oblongata; Neurons; Pons; Rabbits | 1990 |
Anticonvulsant action of an arylamine-containing fraction from Agelenopsis spider venom.
Topics: Animals; Anticonvulsants; Bicuculline; Biogenic Amines; Chemical Fractionation; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Intraventricular; Kainic Acid; Male; Molecular Weight; Picrotoxin; Rats; Rats, Inbred Strains; Spider Venoms | 1990 |
Convulsant-induced changes in perforant path-dentate gyrus excitability in urethane anesthetized rats.
Topics: Animals; Bicuculline; Convulsants; Dose-Response Relationship, Drug; Hexachlorocyclohexane; Hippocampus; Kainic Acid; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Urethane | 1988 |
Muscimol, gamma-aminobutyric acidA receptors and excitatory amino acids in the mouse spinal cord.
Topics: Analgesia; Animals; Aspartic Acid; Baclofen; Behavior, Animal; Bicuculline; Kainic Acid; Male; Mice; Muscimol; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, GABA-A; Spinal Cord; Substance P | 1989 |
Regional voltage map of the hippocampus during seizures.
Topics: Animals; Bicuculline; Diagnosis, Computer-Assisted; Electroencephalography; Electrophysiology; Hippocampus; Kainic Acid; Male; Rats; Rats, Inbred Strains; Seizures; Trypan Blue | 1989 |
GABAergic fibers from substantia nigra pars reticulata modulate escape behavior induced by midbrain central gray stimulation.
Topics: Animals; Bicuculline; Electric Stimulation; Escape Reaction; GABA Antagonists; Kainic Acid; Male; Rats; Rats, Inbred Strains; Substantia Nigra | 1989 |
Regional changes in transmitter amino acids during focal and generalized seizures in rats.
Topics: Allylglycine; Amino Acids; Animals; Bicuculline; Brain; Glucose; Hippocampus; Kainic Acid; Lactates; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Seizures | 1985 |
Role of excitatory amino acid transmission in the genesis of seizures elicited from the deep prepiriform cortex.
Topics: Animals; Aspartic Acid; Bicuculline; Carbachol; Glutamates; Glutamic Acid; Kainic Acid; Limbic System; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Seizures | 1986 |
The mouse neocortical slice: preparation and responses to excitatory amino acids.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Bicuculline; Cerebral Cortex; Corpus Callosum; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; Mice; Mice, Inbred Strains; N-Methylaspartate; Ouabain; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Tetrodotoxin | 1987 |
Effects of status epilepticus on extracellular amino acids in the hippocampus.
Topics: Amino Acids; Animals; Bicuculline; Ethanolamines; Extracellular Space; gamma-Aminobutyric Acid; Hippocampus; Kainic Acid; Rabbits; Status Epilepticus; Synaptic Transmission; Taurine | 1985 |
GABAergic modulation of inferior colliculus excitability: role in the ethanol withdrawal audiogenic seizures.
Topics: Acoustic Stimulation; Animals; Baclofen; Benzodiazepinones; Bicuculline; Ethanol; Geniculate Bodies; Inferior Colliculi; Kainic Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Stereoisomerism; Substance Withdrawal Syndrome | 1986 |
Baclofen suppresses bursting activity induced in hippocampal slices by differing convulsant treatments.
Topics: Action Potentials; Animals; Anticonvulsants; Baclofen; Bicuculline; Convulsants; Epilepsy; Female; Hippocampus; In Vitro Techniques; Kainic Acid; Potassium; Rats; Receptors, GABA-A | 1986 |
Localization of sites in periventricular forebrain mediating cardiovascular effects of gamma-aminobutyric acid agonists and antagonists in anesthetized cats.
Topics: Animals; Bicuculline; Blood Pressure; Brain Mapping; Cats; Cerebral Ventricles; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Hypothalamus; Injections, Intraventricular; Kainic Acid; Muscimol; Receptors, GABA-A; Sympathetic Nervous System; Vagus Nerve | 1987 |
Continuous determination of the cerebrovascular changes induced by bicuculline and kainic acid in unanaesthetized spontaneously breathing rats.
Topics: Action Potentials; Animals; Bicuculline; Blood Pressure; Brain; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Evoked Potentials; Hippocampus; Kainic Acid; Male; Oxygen Consumption; Rats; Rats, Inbred Strains; Seizures | 1987 |
Alterations in extracellular amino acids and Ca2+ following excitotoxin administration and during status epilepticus.
Topics: Amino Acids; Animals; Aspartic Acid; Bicuculline; Calcium; Epilepsy; Ethanolamines; Extracellular Space; Glutamates; Hippocampus; Kainic Acid; N-Methylaspartate; Rabbits; Synaptic Membranes; Synaptosomes; Taurine; Tetrodotoxin | 1986 |
Anterior thalamic mediation of generalized pentylenetetrazol seizures.
Topics: Aminocaproates; Animals; Behavior, Animal; Bicuculline; Cerebral Cortex; Electroencephalography; Female; Guinea Pigs; Kainic Acid; Microinjections; Muscimol; Pentylenetetrazole; Seizures; Stereotaxic Techniques; Thalamic Nuclei; Vigabatrin | 1986 |
Comparison of seizures and brain lesions produced by intracerebroventricular kainic acid and bicuculline methiodide.
Topics: Animals; Bicuculline; Brain Diseases; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Rats; Rats, Inbred Strains; Seizures | 1986 |
Pathophysiological aspects of blood-brain barrier permeability in epileptic seizures.
Topics: Animals; Bicuculline; Blood Pressure; Blood-Brain Barrier; Cerebrovascular Circulation; Endothelium; Epilepsy; Kainic Acid; Methionine Sulfoximine; Pentylenetetrazole; Pyridoxine; Rabbits; Seizures | 1986 |
Kainic acid seizures and neuronal cell death: insights from studies of selective lesions and drugs.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Convulsants; Hippocampus; Kainic Acid; Limbic System; Male; Nerve Degeneration; Neural Inhibition; Neural Pathways; Phenobarbital; Rats; Seizures; Time Factors | 1986 |
Dopamine inhibits calcium-independent gamma-[3H]aminobutyric acid release induced by kainate and high K+ in the fish retina.
Topics: Animals; Aspartic Acid; Bicuculline; Calcium; Dopamine; Fishes; gamma-Aminobutyric Acid; Haloperidol; Kainic Acid; N-Methylaspartate; Oxadiazoles; Picrotoxin; Potassium; Pyrrolidines; Quisqualic Acid; Retina; Serotonin | 1985 |
Brain dopamine activity following intranigral or intrathalamic drug injections in the rat.
Topics: Animals; Bicuculline; Brain Chemistry; Dopamine; Halothane; Injections, Intraventricular; Kainic Acid; Male; Motor Activity; Muscimol; Rats; Rats, Inbred Strains; Stereotaxic Techniques; Substantia Nigra; Thalamus; Time Factors | 1985 |
GABAergic control of the cholinergic projections to the frontal cortex is not tonic.
Topics: Animals; Basal Ganglia; Bicuculline; Cholinergic Fibers; Frontal Lobe; gamma-Aminobutyric Acid; Kainic Acid; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Substantia Innominata | 1985 |
Incongruence of regional cerebral blood flow increase and blood-brain barrier opening in rabbits at the onset of seizures induced by bicuculline, methoxypyridoxine, and kainic acid.
Topics: Animals; Bicuculline; Blood Pressure; Blood-Brain Barrier; Brain; Epilepsy; Kainic Acid; Male; Nicotine; Pyridoxine; Rabbits; Regional Blood Flow | 1985 |
Abolition of spindle oscillations in thalamic neurons disconnected from nucleus reticularis thalami.
Topics: Action Potentials; Animals; Bicuculline; Cats; Decerebrate State; Electroencephalography; Kainic Acid; Nerve Crush; Neural Conduction; Neural Inhibition; Neural Pathways; Neurons; Reaction Time; Thalamic Nuclei | 1985 |
Effect of taurine on depolarizations induced by L-glutamate and other excitatory amino acids in the isolated spinal cord of the frog.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Potassium; Rana catesbeiana; Spinal Cord; Strychnine; Taurine | 1983 |
Changes in regional neurotransmitter amino acid levels in rat brain during seizures induced by L-allylglycine, bicuculline, and kainic acid.
Topics: Allylglycine; Amino Acids; Animals; Aspartic Acid; Bicuculline; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Male; Neurotransmitter Agents; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Taurine | 1984 |
Pharmacological analysis of the central cardiovascular effects of four GABA analogues.
Topics: Animals; Atropine; Bicuculline; Blood Pressure; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Isonicotinic Acids; Isoxazoles; Kainic Acid; Muscimol; Pyrones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Fastigial influences on postural tonus as studied by kainate lesions and by local infusion of GABAergic drugs in the rat.
Topics: Animals; Bicuculline; Cerebellar Nuclei; Diazepam; Functional Laterality; gamma-Aminobutyric Acid; Kainic Acid; Male; Motor Activity; Muscle Tonus; Picrotoxin; Posture; Pyrrolidines; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1984 |
Regional brain glucose metabolism in chemically-induced seizures in the rat.
Topics: Allylglycine; Animals; Bicuculline; Blood Glucose; Brain; Convulsants; Deoxyglucose; Energy Metabolism; Kainic Acid; Male; Rats; Rats, Inbred Strains; Seizures | 1984 |
The septal-hippocampal cholinergic pathway: role in antagonism of pentobarbital anesthesia and regulation by various afferents.
Topics: Acetylcholine; Anesthesia; Animals; Bicuculline; Brain; Hippocampus; Kainic Acid; Male; Neural Pathways; Neurons, Afferent; Parasympathetic Nervous System; Pentobarbital; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1981 |
Metabolic factors during prolonged seizures and their relation to nerve cell death.
Topics: Animals; Bicuculline; Brain; Calcium; Kainic Acid; Papio; Rabbits; Rats; Status Epilepticus | 1983 |
Hippocampal lesions and status epilepticus.
Topics: Allylglycine; Animals; Bicuculline; Cats; Cerebrovascular Circulation; Electroencephalography; Hippocampus; Kainic Acid; Papio; Rats; Status Epilepticus | 1982 |
Alterations in local glucose consumption following systemic administration of kainic acid, bicuculline or metrazol.
Topics: Animals; Bicuculline; Brain; Convulsants; Deoxyglucose; Glucose; Kainic Acid; Male; Pentylenetetrazole; Pyrrolidines; Rats | 1981 |
Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy.
Topics: Animals; Bicuculline; Brain; Deoxy Sugars; Deoxyglucose; Electric Conductivity; Glucose; Kainic Acid; Male; Organ Specificity; Pentylenetetrazole; Pyrrolidines; Rats; Seizures | 1981 |
The behavioural effects of systemically administered kainic acid: a pharmacological analysis.
Topics: Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Haloperidol; Kainic Acid; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Time Factors | 1981 |
Effects of anticonvulsants and glutamate antagonists on the convulsive action of kainic acid.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bemegride; Bicuculline; Drug Interactions; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Mice; Pentylenetetrazole; Picrotoxin; Pyrrolidines; Seizures | 1980 |
Inhibition of NO synthase increases the severity of kainic acid-induced seizures in rodents.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bicuculline; Cerebrovascular Circulation; Enzyme Inhibitors; Indazoles; Kainic Acid; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures | 1994 |
Dissociation of synchronization and excitability in furosemide blockade of epileptiform activity.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Entorhinal Cortex; Extracellular Space; Female; Furosemide; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; Membrane Potentials; Potassium; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Status Epilepticus; Synaptic Transmission | 1995 |
Seizure susceptibility in immature rats with micrencephaly induced by prenatal exposure to methylazoxymethanol acetate.
Topics: Age Factors; Animals; Bicuculline; Body Weight; Brain; Disease Models, Animal; Female; Humans; Infant, Newborn; Kainic Acid; Maternal-Fetal Exchange; Methylazoxymethanol Acetate; Pregnancy; Rats; Rats, Wistar; Seizures | 1995 |
L-type Ca2+ channels mediate joint modulation by gamma-amino-butyric acid and glutamate of [Ca2+]i and neuropeptide secretion in immortalized gonadodropin-releasing hormone neurons.
Topics: Bicuculline; Calcium; Calcium Channels; Cell Line, Transformed; Cytoplasm; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Kainic Acid; Muscimol; N-Methylaspartate; Neurons; Neuropeptides; Potassium Chloride | 1995 |
Hypothalamic sites mediating cardiovascular effects of microinjected bicuculline and EAAs in rats.
Topics: Anesthesia; Animals; Aspartic Acid; Bicuculline; Cardiovascular System; Excitatory Amino Acids; Hypothalamus; Kainic Acid; Male; Microinjections; Rats; Rats, Sprague-Dawley | 1995 |
Neonatal caffeine exposure and seizure susceptibility in adult rats.
Topics: Animals; Animals, Newborn; Bicuculline; Brain; Caffeine; Female; Kainic Acid; Male; Pentylenetetrazole; Picrotoxin; Rats; Receptors, Purinergic P1; Seizures; Sex Factors; Strychnine | 1995 |
Norbinaltorphimine protection against N-methyl-D-aspartic acid-induced convulsions and mortality.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Binding, Competitive; Brain; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Naltrexone; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Interactions between opioid drugs and propofol in laboratory models of seizures.
Topics: Analgesics, Opioid; Animals; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Fentanyl; Kainic Acid; Meperidine; Mice; Mice, Inbred Strains; Morphine; N-Methylaspartate; Propofol; Seizures | 1995 |
GABAA receptor-mediated inhibition of rat substantia nigra dopaminergic neurons by pars reticulata projection neurons.
Topics: Animals; Baclofen; Bicuculline; Dopamine; Electric Stimulation; Evoked Potentials; Globus Pallidus; Kainic Acid; Kinetics; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substantia Nigra; Superior Colliculi; Thalamus; Time Factors | 1995 |
Deep prepiriform cortex modulates kainate-induced hippocampal injury.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Bicuculline; Cerebral Cortex; Electroencephalography; Excitatory Amino Acids; GABA Antagonists; Hippocampus; Kainic Acid; Male; Neural Pathways; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Seizures; Synaptic Transmission | 1994 |
Excitatory somato-sympathetic reflexes are relayed in the caudal ventrolateral medulla in the cat.
Topics: Animals; Baroreflex; Bicuculline; Blood Pressure; Cats; Chemoreceptor Cells; Denervation; Electric Stimulation; gamma-Aminobutyric Acid; Intercostal Nerves; Interneurons; Kainic Acid; Medulla Oblongata; Pressoreceptors; Sympathetic Nervous System; Synaptic Transmission | 1994 |
Enhancement of retinal acetylcholine release by DAMGO: possibly a direct opioid receptor-mediated excitatory effect.
Topics: Acetylcholine; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Male; Rabbits; Rats; Receptors, Opioid, mu; Retina; Strychnine; Xanthines | 1994 |
Neonatal irradiation prevents the formation of hippocampal mossy fibers and the epileptic action of kainate on rat CA3 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Electric Stimulation; Electrophysiology; Epilepsy; Gamma Rays; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; Nerve Fibers; Neurons, Afferent; Potassium; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar | 1994 |
The activity of opioid analgesics in seizure models utilizing N-methyl-DL-aspartic acid, kainic acid, bicuculline and pentylenetetrazole.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Bicuculline; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Kainic Acid; Male; Mice; N-Methylaspartate; Naloxone; Pentylenetetrazole; Seizures | 1994 |
Kainic acid, bicuculline, pentylenetetrazol and pilocarpine elicit maximal dentate activation in the anesthetized rat.
Topics: Anesthesia; Animals; Bicuculline; Convulsants; Electric Stimulation; Epilepsy; Evoked Potentials; Hippocampus; Kainic Acid; Male; Pentylenetetrazole; Pilocarpine; Rats; Rats, Sprague-Dawley | 1994 |
GABAergic nigro-collicular pathways modulate the defensive behaviour elicited by midbrain tectum stimulation.
Topics: Aggression; Animals; Bicuculline; Electric Stimulation; Escape Reaction; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Male; Mesencephalon; Microinjections; Muscimol; Nerve Fibers; Neural Pathways; Rats; Rats, Wistar; Stimulation, Chemical; Substantia Nigra; Superior Colliculi | 1993 |
Experimental seizures in the frog (Rana pipiens).
Topics: Animals; Behavior, Animal; Bicuculline; Brain; Cisplatin; Convulsants; Electroencephalography; Kainic Acid; Pentylenetetrazole; Rana pipiens; Seizures; Strychnine | 1994 |
Effects of the epileptogenic agent bicuculline methiodide on membrane currents induced by N-methyl-D-aspartate and kainate (oocyte; Xenopus laevis).
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Conductivity; Epilepsy; Kainic Acid; N-Methylaspartate; Oocytes; Xenopus laevis | 1994 |
GABA transporters and GABAC-like receptors on catfish cone- but not rod-driven horizontal cells.
Topics: Animals; Baclofen; Bicuculline; Carrier Proteins; Chloride Channels; Crotonates; Electrophysiology; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ictaluridae; Kainic Acid; Kinetics; Membrane Proteins; Membrane Transport Proteins; Muscimol; Organic Anion Transporters; Picrotoxin; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Stereoisomerism; Time Factors | 1994 |
Induction of c-fos mRNA expression in an in vitro hippocampal slice model of adult rats after kainate but not gamma-aminobutyric acid or bicuculline treatment.
Topics: Animals; Animals, Newborn; Bicuculline; gamma-Aminobutyric Acid; Gene Expression; Genes, fos; Hippocampus; In Vitro Techniques; Kainic Acid; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Transcription, Genetic | 1994 |
Interaction between excitatory and inhibitory amino acids in the ventromedial nucleus of the hypothalamus in inducing hyper-running.
Topics: Animals; Bicuculline; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Microinjections; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Ventromedial Hypothalamic Nucleus | 1993 |
Role of the spinal cord in generating the 2- to 6-Hz rhythm in rat sympathetic outflow.
Topics: Animals; Bicuculline; Decerebrate State; Electrophysiology; Injections, Spinal; Kainic Acid; Kynurenic Acid; Lumbosacral Region; Male; Medulla Oblongata; Microinjections; Muscimol; Periodicity; Rats; Rats, Sprague-Dawley; Spinal Cord; Sympathetic Nervous System | 1993 |
Seizures increase trkC mRNA expression in the dentate gyrus of rat hippocampus. Role of glutamate receptor activation.
Topics: Animals; Behavior, Animal; Bicuculline; Cells, Cultured; Dentate Gyrus; Excitatory Amino Acid Agonists; Fetus; GABA-A Receptor Antagonists; Gene Expression; In Situ Hybridization; Injections, Intraventricular; Kainic Acid; Male; Neurons; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptor, trkC; Receptors, Nerve Growth Factor; Ribonucleases; RNA, Messenger; Seizures | 1995 |
A patch clamp study of the effects of ciprofloxacin and biphenyl acetic acid on rat hippocampal neurone GABAA and ionotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Bicuculline; Cells, Cultured; Ciprofloxacin; Drug Interactions; Hippocampus; Kainic Acid; N-Methylaspartate; Patch-Clamp Techniques; Phenylacetates; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glutamate | 1995 |
Spontaneous and stimulation-induced synchronized burst afterdischarges in the isolated CA1 of kainate-treated rats.
Topics: Action Potentials; Animals; Behavior, Animal; Bicuculline; Cell Count; Convulsants; Dentate Gyrus; Epilepsy; Injections; Kainic Acid; Male; Neurons; Perfusion; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1996 |
NG-nitro-L-arginine differentially affects glutamate- or kainate-induced seizures.
Topics: Animals; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; Male; Mice; Mice, Inbred Strains; Nitroarginine; Seizures | 1996 |
A new extracellular multirecording system for electrophysiological studies: application to hippocampal organotypic cultures.
Topics: Animals; Bicuculline; Dexamethasone; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glucocorticoids; Hippocampus; Kainic Acid; Microelectrodes; Organ Culture Techniques; Quinoxalines; Rats; Reproducibility of Results; Tetrodotoxin | 1997 |
Control of dopamine release in the retina: a transgenic approach to neural networks.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alkaline Phosphatase; Animals; Bicuculline; Calcium Channels; Cell Separation; DNA, Complementary; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glycine; Glycine Agents; GPI-Linked Proteins; Humans; Ion Channel Gating; Isoenzymes; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron; Neural Pathways; Neurons; Patch-Clamp Techniques; Potassium Channels; Promoter Regions, Genetic; Rats; Retina; Strychnine; Synapses; Tyrosine 3-Monooxygenase | 1997 |
The GABAA receptor is expressed in human neurons derived from a teratocarcinoma cell line.
Topics: Bicuculline; Cell Differentiation; Electric Conductivity; Evoked Potentials; gamma-Aminobutyric Acid; Humans; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, GABA-A; Sodium Channels; Teratocarcinoma; Tetrodotoxin; Tretinoin; Tumor Cells, Cultured | 1997 |
Kainate receptors presynaptically downregulate GABAergic inhibition in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cells, Cultured; Electric Stimulation; Electroencephalography; Embryo, Mammalian; Epilepsy; Evoked Potentials; Female; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Synaptic Transmission; Tetrodotoxin | 1997 |
Inwardly rectifying and Ca2+-permeable AMPA-type glutamate receptor channels in rat neocortical neurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Calcium; Calcium Channels; Electric Conductivity; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Membrane Potentials; Nerve Fibers; Neurons; Occipital Lobe; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, GABA-A; Spermine; Synapses | 1997 |
Physiological unmasking of new glutamatergic pathways in the dentate gyrus of hippocampal slices from kainate-induced epileptic rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Dentate Gyrus; Electric Stimulation; Electrophysiology; Epilepsy; Epilepsy, Temporal Lobe; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Humans; In Vitro Techniques; Kainic Acid; Male; Motor Activity; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reference Values | 1998 |
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; GABA Antagonists; Hot Temperature; Iontophoresis; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Peptide Fragments; Peptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail | 1998 |
Spread of excitation in chronically lesioned mouse hippocampus determined by laser scanning microscopy.
Topics: Animals; Bicuculline; Electric Stimulation; Female; Fluorescent Dyes; GABA Antagonists; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Neural Inhibition; Neuroglia; Neurons; Pyridinium Compounds; Time Factors | 1998 |
Regional and differential expression of gelatinases in rat brain after systemic kainic acid or bicuculline administration.
Topics: Animals; Bicuculline; Brain; Collagenases; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; GABA Antagonists; Gelatinases; Glial Fibrillary Acidic Protein; Immunoblotting; Kainic Acid; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metalloendopeptidases; Rats; Rats, Sprague-Dawley | 1998 |
Aggressive experience affects the sensitivity of neurons towards pharmacological treatment in the hypothalamic attack area.
Topics: Aggression; Animals; Bicuculline; Excitatory Amino Acid Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Grooming; Hypothalamus; Kainic Acid; Male; Microdialysis; Neurons; Rats; Rats, Wistar; Synaptic Transmission; Videotape Recording | 1998 |
[S]-AR-R 15896AR-A novel anticonvulsant: acute safety, pharmacokinetic and pharmacodynamic properties.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Kainic Acid; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Sprague-Dawley; Seizures; Seizures, Febrile; Strychnine; Time Factors; Weaning | 1999 |
Cell-specific alterations in synaptic properties of hippocampal CA1 interneurons after kainate treatment.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Interneurons; Kainic Acid; Male; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter | 1998 |
Recurrent mossy fiber pathway in rat dentate gyrus: synaptic currents evoked in presence and absence of seizure-induced growth.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Dentate Gyrus; Electric Stimulation; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Feedback; GABA Antagonists; Kainic Acid; Male; Mossy Fibers, Hippocampal; N-Methylaspartate; Organ Culture Techniques; Parasympathomimetics; Patch-Clamp Techniques; Perforant Pathway; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Staining and Labeling; Status Epilepticus; Synapses | 1999 |
A 'long-term-potentiation-like' facilitation of hippocampal synaptic transmission induced by the nootropic nefiracetam.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Bungarotoxins; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Indoles; Isoquinolines; Kainic Acid; Long-Term Potentiation; Maleimides; Mecamylamine; N-Methylaspartate; Nicotinic Antagonists; Nootropic Agents; Organ Culture Techniques; Patch-Clamp Techniques; Pyrrolidinones; Rats; Receptors, Nicotinic; Sulfonamides; Synaptic Transmission | 1999 |
Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures.
Topics: Animals; Antibodies; Anticonvulsants; Antirheumatic Agents; Bicuculline; Cell Count; Electroencephalography; Enzyme-Linked Immunosorbent Assay; Epilepsy; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; Hippocampus; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Male; Microglia; Nerve Degeneration; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Sialoglycoproteins | 1999 |
Abnormal responses to perforant path stimulation in the dentate gyrus of slices from rats with kainate-induced epilepsy and mossy fiber reorganization.
Topics: Action Potentials; Animals; Bicuculline; Dentate Gyrus; Electric Stimulation; Electrophysiology; Epilepsy; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Kainic Acid; Male; Mossy Fibers, Hippocampal; Neuronal Plasticity; Perforant Pathway; Rats; Rats, Sprague-Dawley; Staining and Labeling | 1999 |
Excitotoxic cell death dependent on inhibitory receptor activation.
Topics: Action Potentials; Animals; Bicuculline; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Cerebellar Cortex; Chick Embryo; Chloride Channels; Chlorides; Excitatory Amino Acid Agonists; GABA Antagonists; Glycine; Ion Channel Gating; Ion Transport; Kainic Acid; Neuroprotective Agents; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glycine; Retina; Strychnine | 1999 |
Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Bicuculline; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indoles; Interneurons; Isoxazoles; Kainic Acid; Lidocaine; Maleimides; Naphthalenes; Nerve Tissue Proteins; Patch-Clamp Techniques; Propionates; Protein Kinase C; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 2000 |
Recurrent excitatory connectivity in the dentate gyrus of kindled and kainic acid-treated rats.
Topics: Animals; Bicuculline; Dentate Gyrus; Electric Stimulation; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Kainic Acid; Kindling, Neurologic; Magnesium; Male; Mossy Fibers, Hippocampal; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 2000 |
Long-lasting depolarizations in mitral cells of the rat olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Dendrites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Olfactory Bulb; Olfactory Receptor Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2000 |
Selective susceptibility to inhibitors of GABA synthesis and antagonists of GABA(A) receptor in rats with genetic absence epilepsy.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Carbolines; Convulsants; Electroencephalography; Epilepsy, Absence; Frontal Lobe; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoniazid; Kainic Acid; Limbic System; Male; Parietal Lobe; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Mutant Strains; Rats, Wistar; Seizures; Strychnine | 2000 |
Seizures and neuronal damage in mice lacking vesicular zinc.
Topics: Animals; Bicuculline; Carrier Proteins; Cation Transport Proteins; Convulsants; Dose-Response Relationship, Drug; Electroencephalography; Flurothyl; Genetic Predisposition to Disease; Kainic Acid; Membrane Proteins; Membrane Transport Proteins; Metallothionein 3; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Pentylenetetrazole; Seizures; Synapses; Synaptic Vesicles; Zinc | 2000 |
Extracellular pH responses in CA1 and the dentate gyrus during electrical stimulation, seizure discharges, and spreading depression.
Topics: Animals; Barium; Bicuculline; Cortical Spreading Depression; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Agonists; Female; GABA Antagonists; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Male; Microelectrodes; Neuroglia; Rats; Rats, Sprague-Dawley; Seizures | 2000 |
Propagation of spontaneous synchronized activity in cortical slice cultures recorded by planar electrode arrays.
Topics: Animals; Bicuculline; Cerebral Cortex; Culture Media; Culture Techniques; Electrodes; Kainic Acid; Rats; Seizures | 2000 |
Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Convulsants; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Guanosine; Hippocampus; Hypoxanthine; Inosine; Kainic Acid; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Xanthine | 2000 |
Voltage-dependent Na(+) currents in mammalian retinal cone bipolar cells.
Topics: 4-Aminopyridine; Animals; Bicuculline; Calcium; Cobalt; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Mammals; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptors, GABA; Retina; Retinal Cone Photoreceptor Cells; Sodium; Sodium Channels; Tetrodotoxin; Visual Pathways | 2000 |
Chemical stimulation of the dorsomedial hypothalamus elevates plasma ACTH in conscious rats.
Topics: Adrenocorticotropic Hormone; Air Movements; Animals; Bicuculline; Blood Pressure; Consciousness; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Agonists; GABA Antagonists; Heart Rate; Hypothalamo-Hypophyseal System; Kainic Acid; Locomotion; Male; Microinjections; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Stress, Physiological | 2001 |
Role of dorsal raphe neurons in paradoxical sleep generation in the cat: no evidence for a serotonergic mechanism.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Cats; Excitatory Amino Acid Agonists; Female; GABA Agonists; GABA Antagonists; Kainic Acid; Male; Microdialysis; Muscimol; Neurons; Piperazines; Pyridines; Raphe Nuclei; Serotonin; Serotonin Antagonists; Sleep Stages; Sleep, REM; Wakefulness | 2001 |
Glutamatergic and GABAergic inputs to the RVL mediate cardiovascular adjustments to noxious stimulation.
Topics: Animals; Bicuculline; Blood Pressure; Electric Stimulation; Functional Laterality; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Hemodynamics; Hindlimb; Kainic Acid; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Muscle, Skeletal; Rats; Rats, Wistar; Regional Blood Flow; Sciatic Nerve; Skin; Sympathetic Nervous System; Vasodilation | 2001 |
Excitatory synaptic input to granule cells increases with time after kainate treatment.
Topics: Action Potentials; Animals; Bicuculline; Coloring Agents; Convulsants; Cytoplasmic Granules; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Male; Mossy Fibers, Hippocampal; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Photic Stimulation; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 2001 |
Activation of group III mGluRs inhibits GABAergic and glutamatergic transmission in the substantia nigra pars reticulata.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Aminobutyrates; Animals; Bicuculline; Drug Design; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Nerve Tissue Proteins; Patch-Clamp Techniques; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Substantia Nigra; Xanthenes | 2001 |
Enhanced but fragile inhibition in the dentate gyrus in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis.
Topics: Animals; Bicuculline; Dentate Gyrus; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Epilepsy, Temporal Lobe; Evoked Potentials; Excitatory Amino Acid Agonists; GABA Antagonists; Kainic Acid; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Nerve Degeneration; Neural Inhibition; Neuronal Plasticity; Neurons; Perforant Pathway; Rats; Rats, Long-Evans; Synaptic Transmission | 2001 |
Delayed postnatal development of NMDA receptor function in medium-sized neurons of the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
Morphological and electrophysiological evidence for an ionotropic GABA receptor of novel pharmacology.
Topics: Amacrine Cells; Animals; Bicuculline; Chick Embryo; Chickens; Excitatory Amino Acid Agonists; GABA Antagonists; In Vitro Techniques; Ion Transport; Kainic Acid; Lithium; Neurons; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA; Retina; Retinal Ganglion Cells | 2002 |
Network interactions mediated by new excitatory connections between CA1 pyramidal cells in rats with kainate-induced epilepsy.
Topics: Action Potentials; Animals; Bicuculline; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Neural Pathways; Patch-Clamp Techniques; Periodicity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 2002 |
Interactions between GABAergic and aminoacidergic pathways in the control of gonadotropin and GH secretion in pre-pubertal female rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Bicuculline; Excitatory Amino Acids; Female; Follicle Stimulating Hormone; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Human Growth Hormone; Kainic Acid; Luteinizing Hormone; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Sexual Maturation | 2002 |
Proconvulsant-induced seizures in alpha(4) nicotinic acetylcholine receptor subunit knockout mice.
Topics: 4-Aminopyridine; Animals; Bicuculline; Binding, Competitive; Brain; Convulsants; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; GABA Antagonists; Genotype; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pentylenetetrazole; Potassium Channel Blockers; Receptors, GABA-A; Receptors, Nicotinic; Seizures; Strychnine | 2002 |
The rat ponto-medullary network responsible for paradoxical sleep onset and maintenance: a combined microinjection and functional neuroanatomical study.
Topics: Animals; Bicuculline; Carbachol; Choline O-Acetyltransferase; Cholinergic Agonists; Efferent Pathways; Electroencephalography; Electromyography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Immunohistochemistry; Kainic Acid; Kynurenic Acid; Male; Medulla Oblongata; Phytohemagglutinins; Pons; Proto-Oncogene Proteins c-fos; Pyridazines; Rats; Rats, Sprague-Dawley; Sleep, REM; Tegmentum Mesencephali; Wakefulness | 2002 |
Rapid eye movement sleep induction by microinjection of the GABA-A antagonist bicuculline into the dorsal subcoeruleus area of the rat.
Topics: Animals; Bicuculline; Carbachol; Electroencephalography; Electromyography; GABA Antagonists; Kainic Acid; Locus Coeruleus; Male; Microinjections; Neostigmine; Propranolol; Rats; Rats, Long-Evans; Receptors, GABA-A; Sleep, REM; Time Factors; Vasopressins | 2003 |
Increased dendritic excitability in hippocampal ca1 in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis.
Topics: Action Potentials; Animals; Bicuculline; Dendrites; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Kainic Acid; Male; Neural Inhibition; Neural Pathways; Perforant Pathway; Rats; Rats, Long-Evans; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2003 |
Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Modulators; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; GABA Antagonists; Genetic Predisposition to Disease; Hippocampus; Kainic Acid; Limbic System; Mice; Mice, Knockout; Neurons; Neurotoxins; Polyunsaturated Alkamides; Seizures | 2003 |
Basal ganglia efferents to the brainstem centers controlling postural muscle tone and locomotion: a new concept for understanding motor disorders in basal ganglia dysfunction.
Topics: Animals; Atropine; Basal Ganglia; Basal Ganglia Diseases; Bicuculline; Brain Stem; Cats; Choline O-Acetyltransferase; Disease Models, Animal; Efferent Pathways; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Locomotion; Muscarinic Antagonists; Muscimol; Muscle Tonus; N-Methylaspartate; Neural Inhibition; Picrotoxin; Stimulation, Chemical | 2003 |
Intracellular calcium release resulting from mGluR1 receptor activation modulates GABAA currents in wide-field retinal amacrine cells: a study with caffeine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amacrine Cells; Animals; Anticoagulants; Bicuculline; Caffeine; Calcium; Calcium Channels; Carps; Cells, Cultured; Central Nervous System Stimulants; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Conductivity; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Space; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heparin; Immunohistochemistry; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kainic Acid; Membrane Potentials; Methoxyhydroxyphenylglycol; Organophosphorus Compounds; Patch-Clamp Techniques; Receptors, Cytoplasmic and Nuclear; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Retina; Ryanodine | 2003 |
Seizure-induced plasticity of h channels in entorhinal cortical layer III pyramidal neurons.
Topics: Analysis of Variance; Animals; Bicuculline; Blotting, Western; Cyclic Nucleotide-Gated Cation Channels; Dendrites; Electroencephalography; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Immunohistochemistry; In Vitro Techniques; Ion Channels; Kainic Acid; Male; Membrane Potentials; Muscle Proteins; Neuronal Plasticity; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Seizures; Valine | 2004 |
Activity-dependent endocytic sorting of kainate receptors to recycling or degradation pathways.
Topics: Bicuculline; Calcium; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; GluK2 Kainate Receptor; Hippocampus; Kainic Acid; Lysosomes; N-Methylaspartate; Neurons; Protein Subunits; Protein Transport; Receptors, Kainic Acid; Tetrodotoxin | 2004 |
Changes in mIPSCs and sIPSCs after kainate treatment: evidence for loss of inhibitory input to dentate granule cells and possible compensatory responses.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Bicuculline; Dentate Gyrus; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Agonists; GABA Antagonists; In Vitro Techniques; Kainic Acid; Male; Neural Inhibition; Neurons; Rats; Rats, Sprague-Dawley; Reaction Time; Synaptic Transmission; Tetrodotoxin; Time Factors | 2005 |
GABAB receptors in the medial septum/diagonal band slice from 16-25 day rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Receptors, GABA-A; Septum Pellucidum; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Valine | 2005 |
Presynaptic modulation of synaptic transmission by pregnenolone sulfate as studied by optical recordings.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Analysis of Variance; Animals; Benzylidene Compounds; Bicuculline; Bungarotoxins; Calcium; Calcium Channel Blockers; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Ethylenediamines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Haloperidol; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Pregnenolone; Presynaptic Terminals; Pyridines; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin; Time Factors | 2005 |
Physiological role for casein kinase 1 in glutamatergic synaptic transmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Casein Kinase 1 epsilon; Casein Kinase I; Casein Kinase Ialpha; Casein Kinase Idelta; Corpus Striatum; Egtazic Acid; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kainic Acid; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neocortex; Nerve Tissue Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 2005 |
Electrophysiological properties of human hypothalamic hamartomas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Bicuculline; Cadmium Chloride; Child; Child, Preschool; Drug Interactions; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Glutamic Acid; Hamartoma; Humans; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Infant; Isoenzymes; Kainic Acid; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periodicity; Phosphopyruvate Hydratase; Potassium Channel Blockers; Tetraethylammonium; Tetrodotoxin; Valine | 2005 |
Occurrence of bicuculline-, NMDA- and kainic acid-induced seizures in prenatally methamphetamine-exposed adult male rats.
Topics: Animals; Bicuculline; Central Nervous System Stimulants; Excitatory Amino Acid Agonists; Female; GABA Antagonists; Kainic Acid; Male; Methamphetamine; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Seizures | 2005 |
Kainic acid-induced recurrent mossy fiber innervation of dentate gyrus inhibitory interneurons: possible anatomical substrate of granule cell hyper-inhibition in chronically epileptic rats.
Topics: Animals; Bicuculline; Electrophysiology; GABA Antagonists; Hippocampus; Humans; Immunohistochemistry; Interneurons; Kainic Acid; Male; Mossy Fibers, Hippocampal; Neurons; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2006 |
Kainate receptor activation potentiates GABAergic synaptic transmission in the nucleus accumbens core.
Topics: Animals; Animals, Newborn; Bicuculline; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Male; Neural Inhibition; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Synaptic Transmission | 2006 |
Dissociated gender-specific effects of recurrent seizures on GABA signaling in CA1 pyramidal neurons: role of GABA(A) receptors.
Topics: Animals; Animals, Newborn; Bicuculline; Electroencephalography; Female; Kainic Acid; Male; Mother-Child Relations; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recurrence; Seizures; Sex Characteristics; Sex Factors; Signal Transduction | 2008 |
Chloride-dependent acute excitotoxicity in adult rat retinal ganglion cells.
Topics: Animals; Bicuculline; Chelating Agents; Chlorides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Eye; GABA Antagonists; Glycine Agents; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Papilledema; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Sodium; Strychnine | 2008 |
Activation of the GABA(A) receptor ameliorates the cochlear excitotoxicity caused by kainic acid in the guinea pig.
Topics: Acoustics; Action Potentials; Animals; Baclofen; Bicuculline; Cochlea; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Glutamine; Guinea Pigs; Kainic Acid; Muscimol; Neurons; Receptors, GABA-A | 2008 |
Bumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Bicuculline; Biophysics; Bumetanide; Electric Stimulation; Epilepsy; Excitatory Amino Acid Agents; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Spectrum Analysis | 2009 |
Regulation of glutamate transport in developing rat oligodendrocytes.
Topics: Animals; Animals, Newborn; Aspartic Acid; Benzodiazepines; Bicuculline; Brain; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Fibroblast Growth Factors; GABA Antagonists; Gangliosides; Gene Expression Regulation, Developmental; Glutamic Acid; Kainic Acid; Membrane Potentials; Neurons; O Antigens; Oligodendroglia; Patch-Clamp Techniques; Platelet-Derived Growth Factor; Pregnancy; Quinoxalines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Tetrodotoxin; Tritium | 2009 |
Drug dependent sex-differences in periaqueducatal gray mediated antinociception in the rat.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Bicuculline; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; GABA Antagonists; Kainic Acid; Male; Microinjections; Models, Biological; Nociceptors; Pain Measurement; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Reaction Time; Sex Characteristics; Sex Factors; Time Factors | 2009 |
Anticonvulsant effects of Searsia dentata (Anacardiaceae) leaf extract in rats.
Topics: Anacardiaceae; Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Epilepsy; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 2010 |
Anticonvulsant profile of the alkaloids (+)-erythravine and (+)-11-α-hydroxy-erythravine isolated from the flowers of Erythrina mulungu Mart ex Benth (Leguminosae-Papilionaceae).
Topics: Animals; Anticonvulsants; Bicuculline; Chi-Square Distribution; Disease Models, Animal; Dose-Response Relationship, Drug; Fabaceae; Flowers; Heterocyclic Compounds, 4 or More Rings; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Reaction Time; Seizures | 2011 |
Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome.
Topics: 4-Aminopyridine; Animals; Bicuculline; Brain Waves; Disease Models, Animal; Excitatory Amino Acid Agonists; GABA-A Receptor Antagonists; Hippocampus; Kainic Acid; Methyl-CpG-Binding Protein 2; Mice; Nerve Net; Neurons; Potassium Channel Blockers; Rett Syndrome; Seizures | 2013 |
EPAC inhibition of SUR1 receptor increases glutamate release and seizure vulnerability.
Topics: Animals; Bicuculline; Biophysics; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Glutamic Acid; Guanine Nucleotide Exchange Factors; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Kainic Acid; KATP Channels; Male; Membrane Potentials; Mice; Mice, Knockout; Patch-Clamp Techniques; Probability; Protein Binding; Quinoxalines; Synaptosomes; Transduction, Genetic | 2013 |
Delayed application of the anesthetic propofol contrasts the neurotoxic effects of kainate on rat organotypic spinal slice cultures.
Topics: Animals; Bicuculline; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA-A Receptor Antagonists; Glycine Agents; Hypnotics and Sedatives; In Vitro Techniques; Kainic Acid; Organ Culture Techniques; Phosphopyruvate Hydratase; Propofol; Rats; Spinal Cord; Strychnine; Time Factors | 2016 |
Effects of chemical stimulation of the lateral wings of the dorsal raphe nucleus on panic-like defensive behaviors and Fos protein expression in rats.
Topics: Animals; Behavior, Animal; Bicuculline; Dorsal Raphe Nucleus; Escape Reaction; Excitatory Amino Acid Agonists; GABA-A Receptor Antagonists; Immunohistochemistry; Kainic Acid; Male; Panic; Periaqueductal Gray; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Stimulation, Chemical | 2017 |
Increased gyrification and aberrant adult neurogenesis of the dentate gyrus in adult rats.
Topics: Analysis of Variance; Animals; Atropine Derivatives; Bicuculline; Bromodeoxyuridine; Dentate Gyrus; Excitatory Amino Acid Agonists; Female; GABA-A Receptor Antagonists; In Vitro Techniques; Kainic Acid; Male; Muscarinic Agonists; Neurogenesis; Neuronal Plasticity; Neurons; Parasympatholytics; Phosphopyruvate Hydratase; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time Factors | 2017 |
Domoic acid suppresses hyperexcitation in the network due to activation of kainate receptors of GABAergic neurons.
Topics: Ammonium Chloride; Animals; Bicuculline; Calcium; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Kainic Acid | 2019 |
A microRNA signature of toxic extrasynaptic N-methyl-D-aspartate (NMDA) receptor signaling.
Topics: Animals; Bicuculline; Cells, Cultured; GABA-A Receptor Antagonists; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; MicroRNAs; N-Methylaspartate; Neurotoxins; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ribonuclease III; Seizures; Signal Transduction; Specific Pathogen-Free Organisms; Subcellular Fractions; Transcriptome; Up-Regulation | 2020 |
Spreading depression as an innate antiseizure mechanism.
Topics: 4-Aminopyridine; Animals; Bicuculline; Brain Stem; Cortical Spreading Depression; Depression; Female; Gene Knock-In Techniques; Kainic Acid; Male; Mice; Nervous System; Optogenetics; Penicillins; Potassium Channel Blockers; Seizures; Tetrodotoxin | 2021 |
Presynaptic nigral GPR55 receptors stimulate [
Topics: Animals; Azabicyclo Compounds; Benzoates; Bicuculline; Calcium; Cannabidiol; gamma-Aminobutyric Acid; Kainic Acid; Neurotransmitter Agents; Rats; Receptors, Cannabinoid; Receptors, Dopamine D1; Receptors, G-Protein-Coupled; Receptors, Presynaptic; RNA, Messenger; Substance P; Substantia Nigra; Thapsigargin | 2022 |