Page last updated: 2024-08-21

bicuculline and isoguvacine

bicuculline has been researched along with isoguvacine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199014 (40.00)18.7374
1990's14 (40.00)18.2507
2000's7 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Polc, P1
Falch, E; Kristiansen, U; Krogsgaard-Larsen, P; Lambert, JD1
Drew, CA; Johnston, GA1
Feltz, P; Zhang, ZW1
Christensen, JD; Fjalland, B; Grell, S1
Oveissi, Y; Zarrindast, MR1
Olsen, RW; Snowman, AM1
Iversen, LL; Wong, EH1
Allan, RD; Dickenson, HW1
Allan, AM; Harris, RA1
Astier, H; Roussel, JP; Tapia-Arancibia, L1
Benson, DI; Klepner, CA; Squires, RF1
Mantegazza, P; Tammiso, R; Vicentini, L; Zambotti, F; Zonta, N1
Cavagnini, F; Grandison, L; Guidotti, A; Invitti, SC; Schmid, R1
Mitchell, R1
Bloch, R; Bousquet, P; Feldman, J; Schwartz, J1
Demeneix, BA; Desaulles, E; Feltz, P; Loeffler, JP1
Albin, RL; Kume, A1
Chen, DZ; Chen, SH; Katsura, M; Kuriyama, K; Ohkuma, S1
Hammond, DL; McGowan, MK1
de Koning, HP; Jenks, BG; Roubos, EW; Valentijn, K1
Ben-Ari, Y; Bregestovski, P; Leinekugel, X; Tseeb, V1
Ashworth-Preece, M; Jarrott, B; Krstew, E; Lawrence, AJ1
Hammond, DL; Kaneko, M1
Buckingham, SD; Rauh, J; Sattelle, DB; Schnee, M1
Bas, DE; Calamera, JC; Ritta, MN1
Ben-Ari, Y; Rovira, C1
Ben-Ari, Y; Dzhala, V; Khalilov, I; Khazipov, R1
Chub, N; O'Donovan, MJ1
Ebert, B; Fjalland, B; Hansen, SL; Kristiansen, U1
Canavier, CC; Johnson, SW; Komendantov, AO; Komendantova, OG1
Ben-Ari, Y; Holmes, GL; Khalilov, I; Khazipov, R; Morozova, E; Tyzio, R1
Holmes, GL; Isaev, D; Isaeva, E; Khazipov, R1
Ben-Ari, Y; Holmes, GL; Khazipov, R; Tyzio, R1
Abdul, M; Hoosein, NM; Mccray, SD1

Other Studies

35 other study(ies) available for bicuculline and isoguvacine

ArticleYear
Effects of GABA-mimetic agents on the cat spinal cord.
    Progress in neuro-psychopharmacology, 1979, Volume: 3, Issue:4

    Topics: Animals; Bicuculline; Cats; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Ibotenic Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Neurons, Afferent; Spinal Cord

1979
Electrophysiological studies of the GABAA receptor ligand, 4-PIOL, on cultured hippocampal neurones.
    British journal of pharmacology, 1991, Volume: 104, Issue:1

    Topics: Animals; Bicuculline; Cells, Cultured; Female; Hippocampus; Isonicotinic Acids; Isoxazoles; Membrane Potentials; Neurons; Piperidines; Pregnancy; Rats; Receptors, GABA-A; Spinal Cord

1991
Bicuculline- and baclofen-insensitive gamma-aminobutyric acid binding to rat cerebellar membranes.
    Journal of neurochemistry, 1992, Volume: 58, Issue:3

    Topics: Animals; Baclofen; Bicuculline; Binding Sites; Calcium; Cerebellum; gamma-Aminobutyric Acid; Isonicotinic Acids; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains

1992
Bicuculline blocks nicotinic acetylcholine response in isolated intermediate lobe cells of the pig.
    British journal of pharmacology, 1991, Volume: 102, Issue:1

    Topics: Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; GABA Antagonists; In Vitro Techniques; Isonicotinic Acids; Membrane Potentials; Pyridazines; Receptors, Nicotinic; Solutions; Swine

1991
GABA receptor stimulation increases the release of vasopressin and oxytocin in vitro.
    European journal of pharmacology, 1987, Oct-06, Volume: 142, Issue:1

    Topics: Animals; Arginine Vasopressin; Bicuculline; Electric Stimulation; Female; In Vitro Techniques; Iodine Radioisotopes; Isonicotinic Acids; Oxytocin; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Uterine Contraction; Vasopressins

1987
GABAA and GABAB receptor sites involvement in rat thermoregulation.
    General pharmacology, 1988, Volume: 19, Issue:2

    Topics: Animals; Baclofen; Bicuculline; Body Temperature Regulation; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Isonicotinic Acids; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA-A

1988
Avermectin B1a modulation of gamma-aminobutyric acid/benzodiazepine receptor binding in mammalian brain.
    Journal of neurochemistry, 1985, Volume: 44, Issue:4

    Topics: Animals; Bicuculline; Brain; Cattle; Cell Membrane; Cerebral Cortex; Etazolate; gamma-Aminobutyric Acid; Isonicotinic Acids; Ivermectin; Lactones; Muscimol; Pentobarbital; Rats; Receptors, GABA-A

1985
Modulation of [3H]diazepam binding in rat cortical membranes by GABAA agonists.
    Journal of neurochemistry, 1985, Volume: 44, Issue:4

    Topics: Androstanes; Animals; Azasteroids; Bicuculline; Cell Membrane; Cerebral Cortex; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isonicotinic Acids; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, GABA-A; Taurine

1985
Evidence that antagonism by delta-aminovaleric acid of GABAB receptors in the guinea-pig ileum may be due to an interaction between GABAA and GABAB receptors.
    European journal of pharmacology, 1986, Jan-14, Volume: 120, Issue:1

    Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Bicuculline; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Isonicotinic Acids; Male; Muscle, Smooth; Receptors, GABA-A; Taurine

1986
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes.
    Molecular pharmacology, 1986, Volume: 29, Issue:5

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature

1986
Evidence for a dual effect of gamma-aminobutyric acid on thyrotropin (TSH)-releasing hormone-induced TSH release from perifused rat pituitaries.
    Endocrinology, 1987, Volume: 121, Issue:3

    Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Male; Muscimol; Perfusion; Picrotoxin; Pituitary Gland; Pyridazines; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone

1987
Multiple benzodiazepine receptor complexes: some benzodiazepine recognition sites are coupled to GABA receptors and ionophores.
    Advances in biochemical psychopharmacology, 1980, Volume: 21

    Topics: Animals; Anions; Benzodiazepines; Bicuculline; Brain; Buffers; Flunitrazepam; gamma-Aminobutyric Acid; Haplorhini; Hot Temperature; Ionophores; Isonicotinic Acids; Isoxazoles; Macromolecular Substances; Papio; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter

1980
Effects of some GABA-mimetic drugs on the antinociceptive activity of morphine and beta-endorphin in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 316, Issue:3

    Topics: Analgesics; Animals; beta-Endorphin; Bicuculline; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Morphine; Muscimol; Nicotinic Acids; Nipecotic Acids; Rats

1981
gamma-Aminobutyric acid- and benzodiazepine-binding sites in human anterior pituitary tissue.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:3

    Topics: Adult; Aged; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Isoxazoles; Middle Aged; Muscimol; Pituitary Gland, Anterior; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A

1982
Interactions of agonists and antagonists with a novel type of GABA receptor.
    Biochemical pharmacology, 1982, Aug-15, Volume: 31, Issue:16

    Topics: Animals; Baclofen; Bicuculline; Corpus Striatum; GABA Antagonists; In Vitro Techniques; Isonicotinic Acids; Kinetics; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A

1982
Pharmacological analysis of the central cardiovascular effects of four GABA analogues.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 325, Issue:4

    Topics: Animals; Atropine; Bicuculline; Blood Pressure; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Isonicotinic Acids; Isoxazoles; Kainic Acid; Muscimol; Pyrones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A

1984
Dual population of GABAA and GABAB receptors in rat pars intermedia demonstrated by release of alpha MSH caused by barium ions.
    British journal of pharmacology, 1984, Volume: 82, Issue:1

    Topics: Animals; Baclofen; Barium; Bicuculline; Female; In Vitro Techniques; Isonicotinic Acids; Male; Melanocyte-Stimulating Hormones; Pituitary Gland; Radioimmunoassay; Rats; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism; Stimulation, Chemical

1984
Quantitative autoradiography of 4'-ethynyl-4-n-[2,3-3H2]propylbicycloorthobenzoate binding to the GABAA receptor complex.
    European journal of pharmacology, 1994, Sep-22, Volume: 263, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Animals; Autoradiography; Bicuculline; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; GABA Agonists; Humans; Isonicotinic Acids; Male; Middle Aged; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA; Species Specificity

1994
GABAA receptor stimulation enhances NMDA-induced Ca2+ influx in mouse cerebral cortical neurons in primary culture.
    Brain research. Molecular brain research, 1994, Volume: 27, Issue:1

    Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebral Cortex; Chloride Channels; Dizocilpine Maleate; Dose-Response Relationship, Drug; GABA Agonists; Isonicotinic Acids; Mice; Muscimol; N-Methylaspartate; Neurons; Picrotoxin; Potassium; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate

1994
Antinociception produced by microinjection of L-glutamate into the ventromedial medulla of the rat: mediation by spinal GABAA receptors.
    Brain research, 1993, Aug-20, Volume: 620, Issue:1

    Topics: Animals; Behavior, Animal; Bicuculline; Diazepam; GABA Antagonists; Glutamates; Glutamic Acid; Injections, Spinal; Isonicotinic Acids; Male; Medulla Oblongata; Microinjections; Nociceptors; Pyridazines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, GABA; Skin Temperature; Spinal Cord

1993
Dual action of GABAA receptors on the secretory process of melanotrophs of Xenopus laevis.
    Neuroendocrinology, 1993, Volume: 58, Issue:1

    Topics: alpha-MSH; Animals; Bicuculline; Cyclic AMP; Isonicotinic Acids; Picrotoxin; Receptors, GABA-A; Xenopus laevis

1993
Synaptic GABAA activation induces Ca2+ rise in pyramidal cells and interneurons from rat neonatal hippocampal slices.
    The Journal of physiology, 1995, Sep-01, Volume: 487 ( Pt 2)

    Topics: Animals; Bicuculline; Calcium; Calcium Channels; GABA Agonists; GABA Antagonists; Hippocampus; Interneurons; Ion Channel Gating; Isonicotinic Acids; Male; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA; Synaptic Transmission

1995
Functional GABAA receptors on rat vagal afferent neurones.
    British journal of pharmacology, 1997, Volume: 120, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Bicuculline; Brain Stem; Denervation; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Image Processing, Computer-Assisted; In Vitro Techniques; Isonicotinic Acids; Male; Neurons, Afferent; Nodose Ganglion; Presynaptic Terminals; Pyridazines; Rats; Rats, Inbred WKY; Receptors, GABA-A; Vagus Nerve

1997
Role of spinal gamma-aminobutyric acidA receptors in formalin-induced nociception in the rat.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:2

    Topics: Animals; Bicuculline; Formaldehyde; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Injections, Spinal; Isonicotinic Acids; Male; Pain; Premedication; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Spinal Cord

1997
Pharmacology of skeletal muscle GABA-gated chloride channels in the cockroach Periplaneta americana.
    The Journal of experimental biology, 1997, Volume: 200, Issue:Pt 23

    Topics: Animals; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Flunitrazepam; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Isonicotinic Acids; Male; Motor Neurons; Muscle, Skeletal; Periplaneta; Picrotoxin; Receptors, GABA; Sesterterpenes

1997
Occurrence of GABA and GABA receptors in human spermatozoa.
    Molecular human reproduction, 1998, Volume: 4, Issue:8

    Topics: Bicuculline; Cell Membrane; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Male; Muscimol; Receptors, GABA; Semen; Sperm Motility; Spermatozoa; Tritium

1998
Developmental study of miniature IPSCs of CA3 hippocampal cells: modulation by midazolam.
    Brain research. Developmental brain research, 1999, Apr-12, Volume: 114, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA Modulators; Hippocampus; Isonicotinic Acids; Male; Midazolam; Neural Inhibition; Neurons; Organ Culture Techniques; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Tetrodotoxin

1999
Dual role of GABA in the neonatal rat hippocampus.
    Developmental neuroscience, 1999, Volume: 21, Issue:3-5

    Topics: Animals; Animals, Newborn; Bicuculline; Diazepam; Electrophysiology; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isonicotinic Acids; Nerve Net; Rats; Rats, Wistar

1999
Post-episode depression of GABAergic transmission in spinal neurons of the chick embryo.
    Journal of neurophysiology, 2001, Volume: 85, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Anterior Horn Cells; Bicuculline; Chick Embryo; Chloride Channels; Chlorides; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gramicidin; Ion Transport; Isonicotinic Acids; Membrane Potentials; Nerve Tissue Proteins; Patch-Clamp Techniques; Periodicity; Receptors, GABA-A; Refractory Period, Electrophysiological; Spinal Cord; Synaptic Transmission; Tetrodotoxin

2001
Effects of GABA(A) receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositions.
    British journal of pharmacology, 2001, Volume: 133, Issue:4

    Topics: Animals; Bicuculline; Cells, Cultured; Cerebellum; Cerebral Cortex; Electrophysiology; GABA Agonists; GABA-A Receptor Agonists; Isonicotinic Acids; Isoxazoles; Mice; Neurons; Oocytes; Patch-Clamp Techniques; Piperidines; Pyridazines; Receptors, GABA-A; Xenopus laevis

2001
A modeling study suggests complementary roles for GABAA and NMDA receptors and the SK channel in regulating the firing pattern in midbrain dopamine neurons.
    Journal of neurophysiology, 2004, Volume: 91, Issue:1

    Topics: Animals; Apamin; Bicuculline; Computer Simulation; Dopamine; Drug Interactions; GABA Agonists; GABA Antagonists; In Vitro Techniques; Isonicotinic Acids; Male; Membrane Potentials; Mesencephalon; Models, Neurological; N-Methylaspartate; Neurons; Picrotoxin; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Small-Conductance Calcium-Activated Potassium Channels

2004
Developmental changes in GABAergic actions and seizure susceptibility in the rat hippocampus.
    The European journal of neuroscience, 2004, Volume: 19, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Bicuculline; Disease Susceptibility; Excitatory Postsynaptic Potentials; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isonicotinic Acids; Male; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Potassium; Pyramidal Cells; Rats; Seizures; Time Factors

2004
Anticonvulsant action of GABA in the high potassium-low magnesium model of ictogenesis in the neonatal rat hippocampus in vivo and in vitro.
    Journal of neurophysiology, 2005, Volume: 94, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isonicotinic Acids; Lipoproteins; Magnesium; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium; Pyridazines; Rats; Seizures

2005
Timing of the developmental switch in GABA(A) mediated signaling from excitation to inhibition in CA3 rat hippocampus using gramicidin perforated patch and extracellular recordings.
    Epilepsia, 2007, Volume: 48 Suppl 5

    Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Bicuculline; Calcium Channels; Electrophysiology; Excitatory Postsynaptic Potentials; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gramicidin; Hippocampus; Inhibitory Postsynaptic Potentials; Isonicotinic Acids; Male; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A

2007
Expression of gamma-aminobutyric acid receptor (subtype A) in prostate cancer.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:8

    Topics: Bicuculline; Cell Proliferation; Colonic Neoplasms; Dihydroergotoxine; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Humans; Isonicotinic Acids; Male; Picrotoxin; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, GABA-A; Receptors, GABA-B; Tumor Cells, Cultured

2008