bicuculline has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (61.29) | 18.2507 |
| 2000's | 9 (29.03) | 29.6817 |
| 2010's | 3 (9.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pinnock, RD | 2 |
| Johnson, SW; North, RA | 1 |
| Dunwiddie, TV; Lupica, CR; Proctor, WR | 1 |
| Harrison, NL; Lambert, NA; Teyler, TJ | 1 |
| Alberch, J; Arenas, E; Marsal, J | 1 |
| Randić, M; Wang, RA | 1 |
| Avoli, M; Barbarosie, MT; Nagao, T | 1 |
| Cunningham, JR; Neal, MJ; Paterson, SJ | 1 |
| Brusa, L; D'Amore, A; Lorenzini, P; Massotti, M | 1 |
| Mulder, AH; Ronken, E; Schoffelmeer, AN | 1 |
| Bontempi, B; Sharp, FR | 1 |
| Avoli, M; Lopantsev, V | 1 |
| Brodin, E; Fried, K; Gustafsson, H; Stiller, CO | 1 |
| Budai, D; Fields, HL | 1 |
| Grudt, TJ; Henderson, G | 1 |
| Chavkin, C; Jin, W | 1 |
| Cooper, AJ; Stanford, IM | 1 |
| Han, S; Jia, YS; Ju, G; Liu, QS | 1 |
| Bodnar, RJ; Christian, G; Echo, JA; Lamonte, N; Ragnauth, A; Znamensky, V | 1 |
| Ackerman, TF; Bodnar, RJ; Lamonte, N | 1 |
| Brailoiu, GC; Dun, NJ; Ohtubo, Y; Wu, SY | 1 |
| Chen, SR; Li, DP; Pan, HL; Pan, YZ | 1 |
| Chen, SR; Finnegan, TF; Pan, HL | 2 |
| Berridge, KC; Smith, KS | 1 |
| Commissiong, JW; Krnjević, K; Xiao, C; Ye, JH; Zhou, C | 1 |
| McQuiston, AR | 1 |
| Dretchen, KL; Gillis, RA; Herman, MA; Sahibzada, N; Vicini, S | 1 |
| Cepeda, C; Chatta, P; Evans, CJ; Franklin, L; Levine, MS; Ma, YY | 1 |
| Bailey, CP; Dewey, WL; Gabra, BH; Henderson, G; Hull, LC | 1 |
31 other study(ies) available for bicuculline and enkephalin, ala(2)-mephe(4)-gly(5)-
| Article | Year |
|---|---|
A highly selective kappa-opioid receptor agonist, CI-977, reduces excitatory synaptic potentials in the rat locus coeruleus in vitro.
Topics: Amino Acids; Analgesics; Animals; Benzofurans; Benzomorphans; Bicuculline; Depression, Chemical; Electric Stimulation; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Ligands; Locus Coeruleus; Membrane Potentials; Naloxone; Naltrexone; Picrotoxin; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1992 |
Opioids excite dopamine neurons by hyperpolarization of local interneurons.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Bicuculline; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Male; Membrane Potentials; Mesencephalon; Neurons; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Dissociation of mu and delta opioid receptor-mediated reductions in evoked and spontaneous synaptic inhibition in the rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Axons; Baclofen; Bicuculline; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Synapses | 1992 |
Evidence for mu opiate receptors on inhibitory terminals in area CA1 of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Barium; Bicuculline; Dendrites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Ion Channel Gating; Naloxone; Nerve Endings; Potassium Channels; Quinoxalines; Rats; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
GABAA and GABAB antagonists prevent the opioid inhibition of endogenous acetylcholine release evoked by glutamate from rat neostriatal slices.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Activation of mu-opioid receptor modulates GABAA receptor-mediated currents in isolated spinal dorsal horn neurons.
Topics: Action Potentials; Amino Acid Sequence; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Sequence Data; Muscimol; Naloxone; Naltrexone; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Opioid, mu; Spinal Cord | 1994 |
Control of 4-aminopyridine-induced synchronous activity by adenosine A1 and mu-opioid receptor agonists in adult rat hippocampus.
Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1994 |
Enhancement of retinal acetylcholine release by DAMGO: possibly a direct opioid receptor-mediated excitatory effect.
Topics: Acetylcholine; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Male; Rabbits; Rats; Receptors, Opioid, mu; Retina; Strychnine; Xanthines | 1994 |
Area tempestas modulates the behavioural responses to nociceptive stimuli in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Azocines; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Escape Reaction; Foot; Hot Temperature; Male; Morphine; Naltrexone; Narcotic Antagonists; Olfactory Pathways; Pain; Phenazocine; Pressure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Seizures; Tail | 1993 |
Interacting presynaptic kappa-opioid and GABAA receptors modulate dopamine release from rat striatal synaptosomes.
Topics: Analysis of Variance; Animals; Benzeneacetamides; Bicuculline; Corpus Striatum; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Kinetics; Male; Naltrexone; Narcotics; Oligopeptides; Picrotoxin; Potassium; Pyrrolidines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, kappa; Synaptosomes | 1993 |
Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area.
Topics: Afferent Pathways; Analgesics, Opioid; Animals; Behavior, Animal; Benzazepines; Bicuculline; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Injections; Injections, Intraperitoneal; Interneurons; Morphine; Motor Activity; Naloxone; Nerve Tissue Proteins; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substantia Nigra; Tegmentum Mesencephali | 1997 |
Participation of GABAA-mediated inhibition in ictallike discharges in the rat entorhinal cortex.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Neurons; Potassium Acetate; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1998 |
Opioid-induced release of neurotensin in the periaqueductal gray matter of freely moving rats.
Topics: Analgesics, Opioid; Animals; Bicuculline; Calcium; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Agonists; GABA Antagonists; Male; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Narcotics; Neurotensin; Periaqueductal Gray; Rats; Rats, Sprague-Dawley | 1997 |
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; GABA Antagonists; Hot Temperature; Iontophoresis; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Peptide Fragments; Peptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail | 1998 |
Glycine and GABAA receptor-mediated synaptic transmission in rat substantia gelatinosa: inhibition by mu-opioid and GABAB agonists.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Postsynaptic Potentials; Female; GABA Agents; GABA Antagonists; GABA-B Receptor Agonists; Glycine Agents; In Vitro Techniques; Male; Membrane Potentials; Narcotic Antagonists; Patch-Clamp Techniques; Peptide Fragments; Peptides; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glycine; Receptors, Opioid, mu; Somatostatin; Strychnine; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin | 1998 |
Mu opioids enhance mossy fiber synaptic transmission indirectly by reducing GABAB receptor activation.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Antagonists; Long-Term Potentiation; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Naloxone; Narcotic Antagonists; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission | 1999 |
Presynaptic mu and delta opioid receptor modulation of GABAA IPSCs in the rat globus pallidus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analgesics, Opioid; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Excitatory Amino Acid Antagonists; GABA Antagonists; Globus Pallidus; In Vitro Techniques; Male; Membrane Potentials; Neostriatum; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission; Tetrodotoxin | 1999 |
Selective modulation of excitatory transmission by mu-opioid receptor activation in rat supraoptic neurons.
Topics: Animals; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Male; Membrane Potentials; Morphine; Narcotics; Neurosecretory Systems; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, mu; Supraoptic Nucleus; Synaptic Transmission | 1999 |
gamma-Aminobutyric acid receptor subtype antagonists differentially alter opioid-induced feeding in the shell region of the nucleus accumbens in rats.
Topics: Animals; Baclofen; Bicuculline; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Naltrexone; Narcotic Antagonists; Narcotics; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Receptors, Opioid | 2001 |
Lack of intersite GABA receptor subtype antagonist effects upon mu opioid receptor agonist-induced feeding elicited from either the ventral tegmental area or nucleus accumbens shell in rats.
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Tegmentum Mesencephali | 2003 |
Effects of endomorphin on substantia gelatinosa neurons in rat spinal cord slices.
Topics: Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Postsynaptic Potentials; Female; Male; Membrane Potentials; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord; Substantia Gelatinosa; Tetrodotoxin; Time Factors | 2003 |
Activation of mu-opioid receptors excites a population of locus coeruleus-spinal neurons through presynaptic disinhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Anesthetics, Local; Animals; Bicuculline; Carbocyanines; Dopamine beta-Hydroxylase; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Locus Coeruleus; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Peptides; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord; Tetrodotoxin | 2004 |
Effect of the {mu} opioid on excitatory and inhibitory synaptic inputs to periaqueductal gray-projecting neurons in the amygdala.
Topics: Amygdala; Analgesics, Opioid; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Postsynaptic Potentials; GABA Antagonists; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Neural Pathways; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Synapses; Synaptophysin | 2005 |
The ventral pallidum and hedonic reward: neurochemical maps of sucrose "liking" and food intake.
Topics: Animals; Bicuculline; Brain Chemistry; Brain Mapping; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Food Preferences; Globus Pallidus; Male; Rats; Rats, Sprague-Dawley; Reward; Sucrose | 2005 |
Mu opioid receptor activation inhibits GABAergic inputs to basolateral amygdala neurons through Kv1.1/1.2 channels.
Topics: Amygdala; Analgesics, Opioid; Animals; Bicuculline; Elapid Venoms; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Kv1.1 Potassium Channel; Kv1.2 Potassium Channel; Limbic System; Male; Neurons, Afferent; Nociceptin Receptor; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, mu; Scorpion Venoms; Signal Transduction; Synaptic Transmission; Synaptophysin | 2006 |
Mesencephalic astrocyte-derived neurotrophic factor enhances nigral gamma-aminobutyric acid release.
Topics: Animals; Animals, Newborn; Bicuculline; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Antagonists; gamma-Aminobutyric Acid; Glial Cell Line-Derived Neurotrophic Factor; Humans; In Vitro Techniques; Membrane Potentials; Mesencephalon; Neural Inhibition; Neurons; Patch-Clamp Techniques; Quinpirole; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Effects of mu-opioid receptor modulation on GABAB receptor synaptic function in hippocampal CA1.
Topics: Analgesics, Opioid; Animals; Bicuculline; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Synapses | 2007 |
Tonic GABAA receptor conductance in medial subnucleus of the tractus solitarius neurons is inhibited by activation of μ-opioid receptors.
Topics: Analgesics, Opioid; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Opioid, mu; Sodium Channel Blockers; Solitary Nucleus; Tetrodotoxin | 2012 |
Regional and cell-type-specific effects of DAMGO on striatal D1 and D2 dopamine receptor-expressing medium-sized spiny neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Anesthetics, Local; Animals; Bicuculline; Corpus Striatum; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Green Fluorescent Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Potentials; Tetrodotoxin | 2012 |
Reversal of morphine analgesic tolerance by ethanol in the mouse.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Central Nervous System Depressants; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ethanol; GABA Antagonists; Hypnotics and Sedatives; Immersion; Injections, Intraventricular; Male; Mice; Morphine; Pain Measurement; Receptors, GABA-A; Receptors, GABA-B | 2013 |