Compounds > bicuculline
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bicuculline and chlormethiazole

bicuculline has been researched along with chlormethiazole in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harrison, NL; Simmonds, MA1
Kelder, D; Ross, SB1
Simmonds, MA; Zhong, Y1
Empson, RM; Gee, VJ; Newberry, NR; Sheardown, MJ1
Forsberg, T; Gabrielsson, J; Martinsson, S; Pozarek, S; Ross, SB; Visser, SA1
Addae, JI; Ali, N; Stone, TW; Youssef, FF1

Other Studies

6 other study(ies) available for bicuculline and chlormethiazole

ArticleYear
Two distinct interactions of barbiturates and chlormethiazole with the GABAA receptor complex in rat cuneate nucleus in vitro.
    British journal of pharmacology, 1983, Volume: 80, Issue:2

    Topics: Animals; Barbiturates; Bicuculline; Chlormethiazole; In Vitro Techniques; Male; Medulla Oblongata; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A

1983
Counteraction of the rapid tolerance to 8-OH-DPAT-induced corticosterone secretion in rats by activation of the GABAA receptor-chloride channel complex.
    British journal of pharmacology, 1993, Volume: 109, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzodiazepines; Bicuculline; Chloride Channels; Chlormethiazole; Corticosterone; Drug Tolerance; Ion Channels; Male; Membrane Proteins; Muscimol; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

1993
Interactions between loreclezole, chlormethiazole and pentobarbitone at GABA(A) receptors: functional and binding studies.
    British journal of pharmacology, 1997, Volume: 121, Issue:7

    Topics: Animals; Anticonvulsants; Bicuculline; Chlormethiazole; Flunitrazepam; In Vitro Techniques; Male; Medulla Oblongata; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Triazoles

1997
Chlormethiazole inhibits epileptiform activity by potentiating GABA(A) receptor function.
    Brain research, 2000, Nov-24, Volume: 884, Issue:1--2

    Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; Chlormethiazole; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Valine

2000
Rapid and long-lasting tolerance to clomethiazole-induced hypothermia in the rat.
    European journal of pharmacology, 2005, Apr-11, Volume: 512, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA Modulators; Hypothermia; Injections, Subcutaneous; Male; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Time Factors

2005
AMPA receptor activation reduces epileptiform activity in the rat neocortex.
    Brain research, 2007, Jul-16, Volume: 1158

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzothiadiazines; Bicuculline; Chlormethiazole; Diazepam; Electroencephalography; Epilepsy; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Neocortex; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA

2007