Page last updated: 2024-08-21

bicuculline and 4-aminopyridine

bicuculline has been researched along with 4-aminopyridine in 119 studies

Research

Studies (119)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (8.40)	18.7374
1990's	30 (25.21)	18.2507
2000's	42 (35.29)	29.6817
2010's	34 (28.57)	24.3611
2020's	3 (2.52)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Carcache, D; Kalkman, HO; Koller, M; Mattes, H	1
Banks, MI; Smith, PH	1
Aram, JA; Michelson, HB; Wong, RK	1
Blasquez, C; Bunel, DT; Delbende, C; Jégou, S; Vaudry, H	1
Ives, AE; Jefferys, JG	1
Albowitz, B; Ehrenreich, L; Kuhnt, U	1
Avoli, M; Perreault, P	2
Avoli, M; Olivier, A; Perreault, P; Villemure, JG	1
Jabbur, SJ; Saadé, N; Wall, PD	1
Potapov, AA	1
Aleman, V; de Muñoz, DM	1
Brailowsky, S; Knight, RT	1
Bagust, J; Forsythe, ID; Kerkut, GA; Loots, JM	1
Galvan, M; Grafe, P; ten Bruggencate, G	1
Gross, GW; Rhoades, BK	1
Baraban, SC; Hochman, DW; Owens, JW; Schwartzkroin, PA	1
Avoli, M; Barbarosie, MT; Nagao, T	1
Avoli, M; Psarropoulou, C	1
Bijak, M; Demmelhuber, J; Jarolimek, W; Misgeld, U	1
Higashima, M; Kinoshita, H; Koshino, Y; Yamaguchi, N	1
Barish, ME; Ichikawa, M; Iijima, T; Matsumoto, G; Tominaga, T	1
Borck, C; Colling, SB; Jefferys, JG; Traub, RD	1
Bijak, M; Misgeld, U	1
Rutecki, PA; Yang, Y	1
Avoli, M; Lopantsev, V	1
Ayala, GX; Bargas, J; Galarraga, E; Hernández, E	1
Forti, M; Michelson, HB	1
Wennberg, R; Zhang, L; Zhang, Y	1
Avoli, M; Kawasaki, H; Methot, M	1
Balestra, M; Borrelli, AR; Cramer, CL; Eismann, MS; Freedman, LR; Hudzik, TJ; Knowles, MK; Mahmood, N; McCarthy, DJ; Murray, RJ; Palmer, GC; Stagnitto, ML	1
Bargas, J; Galarraga, E; Hernández-Echeagaray, E	1
D'Ambrosio, R; Hochman, DW; Janigro, D; Schwartzkroin, PA	1
Armand, V; Heinemann, U; Rundfeldt, C	1
Golshani, P; Jones, EG	1
Brückner, C; Heinemann, U; Meierkord, H; Stenkamp, K	1
Batini, C; Vigot, R	1
Beato, M; Nistri, A	1
Erzurumlu, RS; Guido, W; Lo, FS	1
Nedergaard, S	1
Hochman, DW; Schwartzkroin, PA	1
Baraban, SC; Hochman, DW; Schwartzkroin, PA; Wenzel, HJ	1
Hu, HJ; Pan, ZH	1
de Groat, WC; Kawatani, M; Miura, A	1
Ariano, MA; Bunzow, JR; Cepeda, C; Falzone, TL; Flores-Hernandez, J; Grandy, DK; Hurst, RS; Kozell, LB; Levine, MS; Low, MJ; Meshul, CK; Rubinstein, M	1
Angelo, K; Frøkjaer-Jensen, C; Grunnet, M; Jensen, BS; Jespersen, T; Klaerke, DA; Olesen, SP	1
Michelson, HB; Yang, Q	1
Araque, A; Buño, W; Martín, ED	1
Higashima, M; Ohno, K	1
Banczerowski-Pelyhe, I; Détári, L; Dóczi, J; Gulyás-Kovács, A; Tarnawa, I; Világi, I	1
Berkovic, SF; Clark, M; Drago, J; Finkelstein, DI; Horne, MK; Massalas, JS; McColl, C; Powney, E; Ross, SA; Wong, JY	1
Bianchi, R; Chuang, SC; Lee, AC; Shin, HS; Wong, RK	1
Boller, M; Schmidt, M	1
Rutecki, PA; Sayin, U	1
Cobb, SR; Davies, CH; Ferrigan, L; Khoshnood, MJ; Roshan-Milani, S	1
Albrecht, D; Klueva, J; Munsch, T; Pape, HC	1
Bernardi, G; Bonsi, P; Calabresi, P; Costa, C; De Persis, C; Martella, G; Pisani, A; Pisani, F	1
Fritschy, JM; Marty, S; Sotelo, C; Wehrlé, R	1
Bernardi, G; Bracci, E; Calabresi, P; Centonze, D	1
Jiang, L; Kang, J; Kang, N; Nedergaard, M; Xu, J	1
Duchamp, A; Duchamp-Viret, P; Hardy, A; Palouzier-Paulignan, B; Royet, JP	1
Bading, H; Chawla, S; Hardingham, GE; McKenzie, GJ; Papadia, S; Privalsky, M; Stevenson, P; Ward, G	1
Henry, M; Hescheler, J; Schneider, T; Smyth, N; Weiergräber, M	1
Asl, MN; Carlen, PL; Wong, T; Wu, CP; Zhang, L; Zhang, XL	1
Brown, JT; Calver, AR; Collingridge, GL; Davies, CH; Randall, A; Thuault, SJ	1
Fukuda, S; Hisatsune, T; Namba, T; Seki, T; Tozuka, Y	1
Avruch, J; Lenz, G	1
Ruscheweyh, R; Sandkühler, J	1
Borbély, S; Détári, L; Halasy, K; Somogyvári, Z; Világi, I	1
Dimpfel, W	1
Lesser, RP; Motamedi, GK; Ortinski, PI; Rogawski, MA; Salazar, P; Smith, EL; Vicini, S; Webber, WR	1
Chen, Q; Pan, HL	2
Hetman, M; Kalita, K; Kharebava, G; Zheng, JJ	1
Inoue, H; Okada, Y	1
Chapman, CA; Glasgow, SD	1
Bonsi, P; Cuomo, D; Madeo, G; Martella, G; Pisani, A; Platania, P; Sciamanna, G; Tassone, A	1
Fischer, M; Gerich, FJ; Hägele, S; Hildebrandt, B; Katschinski, D; Müller, M; Reuter, J	1
Avoli, M; de Curtis, M; Uva, L	1
Bradley, RM; Suwabe, T	1
Hou, X; Wang, X; Yang, B; Yu, G; Zhang, L; Zhou, J	1
Smith, AJ; Smith, RA; Stone, TW; Tauskela, JS	1
Bell, KF; Fricker, M; Habel, M; Hardingham, GE; Ikonomidou, C; Léveillé, F; Martel, MA; Papadia, S; Puddifoot, C; Soriano, FX; Tolkovsky, AM; Wyllie, DJ	1
Haufler, D; Lacaille, JC; Morin, F; Skinner, FK	1
Avoli, M; Dzakpasu, R; Gonzalez-Sulser, A; Motamedi, GK; Vicini, S; Wang, J	1
Haghdoost-Yazdi, H; Janahmadi, M; Rajaei, F	1
Burnett, AL; Ferreira, JM; Rameau, GA	1
Becker, AJ; Friedman, A; Gitler, D; Kahn, J; Ketzef, M; Weissberg, I	1
Chang, WP; Lee, CM; Shyu, BC; Vogt, BA; Wu, JS	1
Coquinco, A; Craig, AM; Cynader, M; Kaufman, AM; Lee, H; Milnerwood, AJ; Raymond, LA; Sepers, MD; She, K; Wang, L	1
Krogh, KA; Li, Y; Thayer, SA	1
Bontempi, B; Buisson, A; De Koninck, P; El Gaamouch, F; Labrecque, S; Lemieux, M; Moustié, O; Nicole, O	1
Bird, A; Cobb, SR; Ganley, R; McLeod, F; Selfridge, J; Williams, L	1
Barone, C; Biella, G; Consalez, GG; Corbetta, S; Croci, L; de Curtis, I; Montinaro, V; Pennucci, R; Spaiardi, P; Talpo, F; Vaghi, V	1
Krogh, KA; Li, Y; Popko, J; Thayer, SA	1
Mealing, GA; Tauskela, JS; Thivierge, JP; Vincent, K	1
Carriero, G; de Curtis, M; Franceschetti, S; Liautard, C; Mantegazza, M; Scalmani, P	1
Cha, YM; Chen, LF; Frank, CL; West, AE; Wijayatunge, R; Zannas, AS	1
Chang, WP; Lu, HC; Shyu, BC	1
Breschi, GL; de Curtis, M; Gnatkovsky, V; Taverna, S; Uva, L	1
López-Pérez, S; Medina-Ceja, L; Morales-Villagrán, A; Ortega-Ibarra, J; Pardo-Peña, K	1
Accorsi-Mendonça, D; Almado, CE; Bonagamba, LG; Castania, JA; Machado, BH; Moraes, DJ	1
Hasegawa, M; Hongo, Y; Ikegaya, Y; Ogawa, K; Sakaguchi, G; Takasu, K	1
Agudelo-Toro, A; Moses, E; Neef, A; Rotem, A; Stern, S	1
Aylsworth, A; Blondeau, N; Brunette, E; Hewitt, M; Tauskela, JS	1
Cao, W; Chen, L; Lu, W; Luo, J; Qian, T; Wang, J; Zhang, P	1
Baldelli, P; Benfenati, F; Cappetti, B; Forte, N; Medrihan, L	1
Bading, H; Bengtson, CP; Pruunsild, P	1
Avoli, M; Boido, D; de Curtis, M; Lévesque, M; Uva, L	1
Khin, PP; Sohn, UD; Zaw, TS	1
Ahn, S; Jo, S; Jun, SB; Lee, HW; Lee, S	1
Jing, XP; Liu, R; Man, HY; Qiu, M; Shentu, YP; Wang, JZ; Wang, Q; Wang, XC; Yan, X; Zeng, J; Zhou, XW	1
Derbenev, AV; Gao, H; Heesch, CM; Korim, WS; Yao, ST	1
Buée, L; Didier, S; Domise, M; Marinangeli, C; Sauvé, F; Vingtdeux, V	1
Ayata, C; Chung, DY; de Morais, AL; Endres, M; Loonen, ICM; Misra, A; Qin, T; Schiff, SJ; Schlunk, F; Tamim, I	1
Chen, K; Fang, H; Gao, S; Hu, S; Sun, X; Wang, H	1
Estin, J; Li, D; Li, J; Lin, W; Liou, JY; Luo, P; Ma, H; Niemeyer, JE; Schwartz, TH; Yang, F; Zhan, F; Zhao, M	1

Other Studies

119 other study(ies) available for bicuculline and 4-aminopyridine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonists: from bench to bedside. Journal of medicinal chemistry, 2010, Aug-12, Volume: 53, Issue:15 Topics: Analgesics; Animals; Anticonvulsants; Antipsychotic Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Neuroprotective Agents; Protein Subunits; Receptors, AMPA	2010
Intracellular recordings from neurobiotin-labeled cells in brain slices of the rat medial nucleus of the trapezoid body. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:7 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Bicuculline; Biotin; Cochlear Nerve; Electric Conductivity; In Vitro Techniques; Male; Membrane Potentials; Nerve Fibers; Neurons; Pons; Quinoxalines; Rats; Rats, Inbred Strains; Strychnine	1992
Synchronized GABAergic IPSPs recorded in the neocortex after blockade of synaptic transmission mediated by excitatory amino acids. Journal of neurophysiology, 1991, Volume: 65, Issue:5 Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Picrotoxin; Quinoxalines; Synapses; Synaptic Transmission	1991
Effects of ions and ionic channel activators or blockers on release of alpha-MSH from perifused rat hypothalamic slices. Brain research. Molecular brain research, 1990, Volume: 8, Issue:2 Topics: 4-Aminopyridine; alpha-MSH; Animals; Bicuculline; Calcium; Chlorides; Hypothalamus; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Muscimol; Ouabain; Potassium; Rats; Rats, Inbred Strains; Secretory Rate; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Veratridine	1990
Synchronization of epileptiform bursts induced by 4-aminopyridine in the in vitro hippocampal slice preparation. Neuroscience letters, 1990, May-04, Volume: 112, Issue:2-3 Topics: 4-Aminopyridine; Animals; Bicuculline; Epilepsy; Hippocampus; In Vitro Techniques; Male; Neural Conduction; Rats; Rats, Inbred Strains; Recruitment, Neurophysiological	1990
Optical recording of epileptiform voltage changes in the neocortical slice. Experimental brain research, 1990, Volume: 81, Issue:2 Topics: 4-Aminopyridine; Amifampridine; Animals; Bicuculline; Cerebral Cortex; Convulsants; Electrophysiology; Epilepsy; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Membrane Potentials	1990
Effects of low concentrations of 4-aminopyridine on CA1 pyramidal cells of the hippocampus. Journal of neurophysiology, 1989, Volume: 61, Issue:5 Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Bicuculline; Central Nervous System Stimulants; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin	1989
4-Aminopyridine induces a long-lasting depolarizing GABA-ergic potential in human neocortical and hippocampal neurons maintained in vitro. Neuroscience letters, 1988, Dec-05, Volume: 94, Issue:3 Topics: 4-Aminopyridine; Aminopyridines; Bicuculline; Cerebral Cortex; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Humans; In Vitro Techniques; Neurons	1988
Effects of 4-aminopyridine, GABA and bicuculline on cutaneous receptive fields of cat dorsal horn neurons. Brain research, 1985, Oct-07, Volume: 344, Issue:2 Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cats; gamma-Aminobutyric Acid; Neurons, Afferent; Sensation; Skin; Spinal Cord; Synaptic Transmission	1985
A GABAergic depolarizing potential in the hippocampus disclosed by the convulsant 4-aminopyridine. Brain research, 1987, Jan-01, Volume: 400, Issue:1 Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Bicuculline; Evoked Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Rats; Receptors, GABA-A	1987
[Pharmacologic study of the inhibition of the glomerular input to the olfactory tubercle of the frog induced by a puff of air on the olfactory mucosa]. Neirofiziologiia = Neurophysiology, 1987, Volume: 19, Issue:1 Topics: 4-Aminopyridine; Aminooxyacetic Acid; Aminopyridines; Animals; beta-Alanine; Bicuculline; gamma-Aminobutyric Acid; Male; Neuroglia; Olfactory Bulb; Olfactory Mucosa; Physical Stimulation; Rana temporaria; Synaptic Transmission	1987
Effect of different convulsant drugs on some seizure parameters in morphine-dependent mice. Experimental neurology, 1983, Volume: 80, Issue:2 Topics: 3-Mercaptopropionic Acid; 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Brain; Convulsants; Humans; Mice; Morphine Dependence; Pentylenetetrazole; Receptors, Opioid; Seizures; Strychnine	1983
Inhibitory modulation of cat somatosensory cortex: a pharmacological study. Brain research, 1984, Nov-26, Volume: 322, Issue:2 Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cats; Evoked Potentials; Evoked Potentials, Somatosensory; Female; gamma-Aminobutyric Acid; Neural Inhibition; Picrotoxin; Somatosensory Cortex; Taurine	1984
Synaptic and non-synaptic components of the dorsal horn potential in isolated hamster spinal cord. Brain research, 1982, Feb-04, Volume: 233, Issue:1 Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cricetinae; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Magnesium; Neurons, Afferent; Picrotoxin; Potassium; Spinal Cord; Synapses; Temperature; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors	1982
4-Aminopyridine reveals presynaptic GABA actions in rat sympathetic ganglia. Advances in biochemical psychopharmacology, 1981, Volume: 29 Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Rats; Synapses	1981
Potassium and calcium channel dependence of bursting in cultured neuronal networks. Brain research, 1994, Apr-18, Volume: 643, Issue:1-2 Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Apamin; Barium Compounds; Bicuculline; Calcium Channels; Cesium; Charybdotoxin; Chlorides; Choline; Diltiazem; Electrophysiology; Fetus; Magnesium Chloride; Mice; Muscarine; N-Methylaspartate; Nerve Net; Neurons; Organ Culture Techniques; Ouabain; Potassium Channels; Potassium Chloride; Scorpion Venoms; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Veratridine	1994
Dissociation of synchronization and excitability in furosemide blockade of epileptiform activity. Science (New York, N.Y.), 1995, Oct-06, Volume: 270, Issue:5233 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Entorhinal Cortex; Extracellular Space; Female; Furosemide; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; Membrane Potentials; Potassium; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Status Epilepticus; Synaptic Transmission	1995
Control of 4-aminopyridine-induced synchronous activity by adenosine A1 and mu-opioid receptor agonists in adult rat hippocampus. Neuroscience letters, 1994, Dec-05, Volume: 182, Issue:2 Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu	1994
4-Aminopyridine-induced spreading depression episodes in immature hippocampus: developmental and pharmacological characteristics. Neuroscience, 1993, Volume: 55, Issue:1 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cortical Spreading Depression; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate	1993
CGP 55845A blocks baclofen, gamma-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons. Neuroscience letters, 1993, May-14, Volume: 154, Issue:1-2 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Potassium Channels; Quinoxalines; Synapses	1993
Activation of GABAergic function necessary for afterdischarge generation in rat hippocampal slices. Neuroscience letters, 1996, Mar-29, Volume: 207, Issue:2 Topics: 4-Aminopyridine; Animals; Bicuculline; Electric Stimulation; Epilepsy; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors	1996
Enhanced fast synaptic transmission and a delayed depolarization induced by transient potassium current blockade in rat hippocampal slice as studied by optical recording. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Sep-15, Volume: 16, Issue:18 Topics: 4-Aminopyridine; Animals; Bicuculline; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glutamine; Hippocampus; In Vitro Techniques; Male; Microelectrodes; Optics and Photonics; Potassium; Presynaptic Terminals; Rats; Signal Transduction; Synapses; Synaptic Transmission; Time Factors	1996
On the structure of ictal events in vitro. Epilepsia, 1996, Volume: 37, Issue:9 Topics: 4-Aminopyridine; Action Potentials; Animals; Axons; Bicuculline; Brain; Computer Simulation; Dendrites; Electroencephalography; Epilepsy; Hippocampus; Humans; In Vitro Techniques; Male; Microelectrodes; Models, Neurological; Neural Networks, Computer; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	1996
Suppression by GABAB receptors of 4-aminopyridine-induced hyperactivity in guinea-pig dentate neurons. Neuroscience letters, 1996, Feb-16, Volume: 205, Issue:1 Topics: 4-Aminopyridine; Animals; Bicuculline; Dentate Gyrus; Guinea Pigs; Hippocampus; Membrane Potentials; Picrotoxin; Receptors, GABA-B	1996
Metabotropic glutamate receptor activation modulates epileptiform activity in the hippocampus. Neuroscience, 1997, Volume: 81, Issue:4 Topics: 4-Aminopyridine; Adrenergic Antagonists; Animals; Bicuculline; Cholinergic Antagonists; Cycloleucine; Electrophysiology; Epilepsy; GABA Antagonists; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Neurotransmitter Agents; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate	1997
Participation of GABAA-mediated inhibition in ictallike discharges in the rat entorhinal cortex. Journal of neurophysiology, 1998, Volume: 79, Issue:1 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Neurons; Potassium Acetate; Rats; Rats, Sprague-Dawley; Receptors, GABA-A	1998
Ca2+-channels involved in neostriatal glutamatergic transmission. Brain research bulletin, 1998, Mar-15, Volume: 45, Issue:5 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Magnesium; Neostriatum; Rats; Rats, Wistar; Synapses; Synaptic Transmission	1998
Synaptic connectivity of distinct hilar interneuron subpopulations. Journal of neurophysiology, 1998, Volume: 79, Issue:6 Topics: 4-Aminopyridine; Animals; Bicuculline; Cell Communication; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Guinea Pigs; In Vitro Techniques; Interneurons; Membrane Potentials; Pyramidal Cells; Receptors, GABA-A; Receptors, GABA-B; Synapses	1998
Multiple actions of methohexital on hippocampal CA1 and cortical neurons of rat brain slices. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:3 Topics: 4-Aminopyridine; Action Potentials; Anesthetics, Intravenous; Animals; Bicuculline; Cerebral Cortex; Hippocampus; In Vitro Techniques; Male; Methohexital; Rats; Rats, Wistar; Receptors, GABA-A; Synapses	1998
GABA-dependent generation of ectopic action potentials in the rat hippocampus. The European journal of neuroscience, 1998, Volume: 10, Issue:8 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Piperazines; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors	1998
[S]-AR-R 15896AR-A novel anticonvulsant: acute safety, pharmacokinetic and pharmacodynamic properties. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:1 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Kainic Acid; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Sprague-Dawley; Seizures; Seizures, Febrile; Strychnine; Time Factors; Weaning	1999
3-Alpha-chloro-imperialine, a potent blocker of cholinergic presynaptic modulation of glutamatergic afferents in the rat neostriatum. Neuropharmacology, 1998, Volume: 37, Issue:12 Topics: 4-Aminopyridine; Afferent Pathways; Animals; Atropine; Bicuculline; Carbachol; Cevanes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Gallamine Triethiodide; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neostriatum; Neurons; Pirenzepine; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Muscarinic; Synapses	1998
Extracellular chloride and the maintenance of spontaneous epileptiform activity in rat hippocampal slices. Journal of neurophysiology, 1999, Volume: 81, Issue:1 Topics: 4-Aminopyridine; Animals; Bicuculline; Chlorides; Diuretics; Epilepsy; Furosemide; GABA Antagonists; Hippocampus; In Vitro Techniques; Microelectrodes; Rats; Rats, Sprague-Dawley	1999
Effects of retigabine (D-23129) on different patterns of epileptiform activity induced by 4-aminopyridine in rat entorhinal cortex hippocampal slices. Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:1 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Carbamates; Convulsants; Electrophysiology; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; In Vitro Techniques; Phenylenediamines; Rats; Rats, Wistar; Seizures	1999
Synchronized paroxysmal activity in the developing thalamocortical network mediated by corticothalamic projections and "silent" synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Apr-15, Volume: 19, Issue:8 Topics: 4-Aminopyridine; Animals; Bicuculline; Cerebral Cortex; GABA Antagonists; Membrane Potentials; Mice; Mice, Inbred ICR; Nerve Net; Neural Pathways; Oscillometry; Patch-Clamp Techniques; Periodicity; Synapses; Thalamus	1999
Epileptiform discharges induced by combined application of bicuculline and 4-aminopyridine are resistant to standard anticonvulsants in slices of rats. Neuroscience letters, 1999, Jun-25, Volume: 268, Issue:3 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Convulsants; Entorhinal Cortex; Epilepsy; Evoked Potentials; Hippocampus; Rats	1999
Purkinje cell inhibitory responses to 3-APPA (3-aminopropylphosphinic acid) in RAT cerebellar slices. Neuroscience research, 1999, Volume: 34, Issue:3 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Cerebellum; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Purkinje Cells; Rats; Rats, Sprague-Dawley; Tetrodotoxin	1999
Interaction between disinhibited bursting and fictive locomotor patterns in the rat isolated spinal cord. Journal of neurophysiology, 1999, Volume: 82, Issue:5 Topics: 4-Aminopyridine; Animals; Animals, Newborn; Bicuculline; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Magnesium; Models, Neurological; Motor Activity; Motor Neurons; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Wistar; Serotonin; Spinal Cord; Spinal Nerve Roots; Strychnine	1999
Electrophysiological properties and synaptic responses of cells in the trigeminal principal sensory nucleus of postnatal rats. Journal of neurophysiology, 1999, Volume: 82, Issue:5 Topics: 4-Aminopyridine; Animals; Animals, Newborn; Bicuculline; Brain Mapping; Cell Membrane; Cesium; Chlorides; Electric Stimulation; Hair; In Vitro Techniques; Membrane Potentials; Models, Neurological; Neurons; Nickel; Rats; Rats, Sprague-Dawley; Synapses; Thalamus; Trigeminal Nerve; Trigeminal Nuclei; Vibrissae	1999
Regulation of action potential size and excitability in substantia nigra compacta neurons: sensitivity to 4-aminopyridine. Journal of neurophysiology, 1999, Volume: 82, Issue:6 Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; GABA-A Receptor Antagonists; Guinea Pigs; In Vitro Techniques; Ion Channels; Male; Mesencephalon; Neurons; Substantia Nigra; Tetraethylammonium	1999
Chloride-cotransport blockade desynchronizes neuronal discharge in the "epileptic" hippocampal slice. Journal of neurophysiology, 2000, Volume: 83, Issue:1 Topics: 4-Aminopyridine; Animals; Axons; Bicuculline; Carrier Proteins; Chlorides; Electric Stimulation; Epilepsy; Evoked Potentials; Excitatory Postsynaptic Potentials; Furosemide; Hippocampus; In Vitro Techniques; Neurons; Potassium; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters; Synapses; Synaptic Transmission	2000
Characterization of heterotopic cell clusters in the hippocampus of rats exposed to methylazoxymethanol in utero. Epilepsy research, 2000, Volume: 39, Issue:2 Topics: 4-Aminopyridine; Animals; Bicuculline; Brain Diseases; Choristoma; Convulsants; Electrophysiology; Epilepsy; Female; Hippocampus; Methylazoxymethanol Acetate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Synapses	2000
Voltage-dependent Na(+) currents in mammalian retinal cone bipolar cells. Journal of neurophysiology, 2000, Volume: 84, Issue:5 Topics: 4-Aminopyridine; Animals; Bicuculline; Calcium; Cobalt; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Mammals; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptors, GABA; Retina; Retinal Cone Photoreceptor Cells; Sodium; Sodium Channels; Tetrodotoxin; Visual Pathways	2000
Effects of pituitary adenylate cyclase activating polypeptide on lumbosacral preganglionic neurons in the neonatal rat spinal cord. Brain research, 2001, Mar-23, Volume: 895, Issue:1-2 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amidines; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA Antagonists; Glycine Agents; Lumbar Vertebrae; Neurons; Neuropeptides; Parasympathetic Nervous System; Patch-Clamp Techniques; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sacrum; Spinal Cord; Strychnine; Valine	2001
Dopamine D4 receptor-deficient mice display cortical hyperexcitability. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jun-01, Volume: 21, Issue:11 Topics: 4-Aminopyridine; Animals; Bicuculline; Cerebral Cortex; Convulsants; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Membrane Potentials; Mice; Mice, Neurologic Mutants; Motor Cortex; Neural Inhibition; Patch-Clamp Techniques; Piperazines; Presynaptic Terminals; Pyramidal Cells; Receptors, Dopamine D2; Receptors, Dopamine D4; Seizures; Sulfonamides	2001
Pharmacological modulation of SK3 channels. Neuropharmacology, 2001, Volume: 40, Issue:7 Topics: 4-Aminopyridine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Apamin; Bicuculline; Cell Line; Humans; Neuroprotective Agents; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Riluzole; Small-Conductance Calcium-Activated Potassium Channels	2001
Gap junctions synchronize the firing of inhibitory interneurons in guinea pig hippocampus. Brain research, 2001, Jul-13, Volume: 907, Issue:1-2 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Carbenoxolone; Convulsants; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gap Junctions; Guinea Pigs; Hippocampus; Interneurons; Piperazines; Pyramidal Cells; Receptors, AMPA; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	2001
Synaptic regulation of the slow Ca2+-activated K+ current in hippocampal CA1 pyramidal neurons: implication in epileptogenesis. Journal of neurophysiology, 2001, Volume: 86, Issue:6 Topics: 4-Aminopyridine; Animals; Bicuculline; Calcium; Convulsants; Electric Stimulation; Epilepsy; Hippocampus; Magnesium; Male; Potassium Channels, Calcium-Activated; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glutamate; Synapses	2001
Effects of antiepileptic drugs on afterdischarge generation in rat hippocampal slices. Brain research, 2002, Jan-04, Volume: 924, Issue:1 Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Bicuculline; Carbamazepine; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; GABA Antagonists; Hippocampus; Male; Neurons; Phenytoin; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley	2002
Comparison of spontaneous and evoked epileptiform activity in three in vitro epilepsy models. Brain research, 2002, Aug-02, Volume: 945, Issue:2 Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Anti-Anxiety Agents; Benzodiazepines; Bicuculline; Convulsants; Electric Stimulation; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Female; Magnesium Deficiency; Male; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex	2002
Proconvulsant-induced seizures in alpha(4) nicotinic acetylcholine receptor subunit knockout mice. Neuropharmacology, 2002, Volume: 43, Issue:1 Topics: 4-Aminopyridine; Animals; Bicuculline; Binding, Competitive; Brain; Convulsants; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; GABA Antagonists; Genotype; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pentylenetetrazole; Potassium Channel Blockers; Receptors, GABA-A; Receptors, Nicotinic; Seizures; Strychnine	2002
Role of synaptic metabotropic glutamate receptors in epileptiform discharges in hippocampal slices. Journal of neurophysiology, 2002, Volume: 88, Issue:4 Topics: 4-Aminopyridine; Action Potentials; Animals; Benzoates; Bicuculline; Epilepsy; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Hippocampus; Isoenzymes; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Culture Techniques; Phospholipase C beta; Potassium Channel Blockers; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synapses; Type C Phospholipases	2002
GABAC receptors in the rat superior colliculus and pretectum participate in synaptic neurotransmission. Journal of neurophysiology, 2003, Volume: 89, Issue:4 Topics: 4-Aminopyridine; Animals; Bicuculline; Cell Size; GABA Antagonists; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channel Blockers; Propanolamines; Rats; Rats, Long-Evans; Receptors, GABA; Superior Colliculi; Synaptic Transmission	2003
Group I metabotropic glutamate receptor activation produces prolonged epileptiform neuronal synchronization and alters evoked population responses in the hippocampus. Epilepsy research, 2003, Volume: 53, Issue:3 Topics: 4-Aminopyridine; Animals; Bicuculline; Electric Stimulation; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Neurons; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Metabotropic Glutamate; Synaptic Transmission	2003
Regulation of epileptiform activity in hippocampus by nicotinic acetylcholine receptor activation. Epilepsy research, 2003, Volume: 56, Issue:1 Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Action Potentials; Analysis of Variance; Animals; Bicuculline; Choline; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Regression Analysis	2003
Synaptic and non-synaptic mechanisms of amygdala recruitment into temporolimbic epileptiform activities. The European journal of neuroscience, 2003, Volume: 18, Issue:10 Topics: 4-Aminopyridine; Action Potentials; Amygdala; Anesthetics, Local; Animals; Anti-Ulcer Agents; Bicuculline; Carbenoxolone; Dissection; Electric Stimulation; Entorhinal Cortex; Epilepsy; Evoked Potentials; Extracellular Space; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Neurons; Phosphinic Acids; Potassium; Propanolamines; Rats; Rats, Wistar; Reaction Time; Synapses; Tetrodotoxin; Time Factors	2003
Intracellular calcium increase in epileptiform activity: modulation by levetiracetam and lamotrigine. Epilepsia, 2004, Volume: 45, Issue:7 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Epilepsy; Lamotrigine; Levetiracetam; Male; Membrane Potentials; Neocortex; Patch-Clamp Techniques; Piracetam; Pyramidal Cells; Rats; Rats, Wistar; Triazines	2004
Quantitative effects produced by modifications of neuronal activity on the size of GABAA receptor clusters in hippocampal slice cultures. The European journal of neuroscience, 2004, Volume: 20, Issue:2 Topics: 4-Aminopyridine; Age Factors; Animals; Animals, Newborn; Bicuculline; Cell Count; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Isoenzymes; Neural Inhibition; Neurons; Organ Culture Techniques; Phosphopyruvate Hydratase; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Synapses	2004
Engagement of rat striatal neurons by cortical epileptiform activity investigated with paired recordings. Journal of neurophysiology, 2004, Volume: 92, Issue:5 Topics: 4-Aminopyridine; Animals; Bicuculline; Cerebral Cortex; Corpus Striatum; Epilepsies, Partial; Male; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate	2004
Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-16, Volume: 25, Issue:7 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anisomycin; Bicuculline; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Emetine; Excitatory Amino Acid Antagonists; Learning; Long-Term Potentiation; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channels; Propanolamines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels	2005
5-Hydroxytryptamine action in the rat olfactory bulb: in vitro electrophysiological patch-clamp recordings of juxtaglomerular and mitral cells. Neuroscience, 2005, Volume: 131, Issue:3 Topics: 4-Aminopyridine; Animals; Animals, Newborn; Apamin; Benzodiazepines; Bicuculline; Cesium; Chlorides; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Free Radical Scavengers; GABA Antagonists; In Vitro Techniques; Kynurenic Acid; Logistic Models; Membrane Potentials; Methysergide; Mianserin; Neurons; Nickel; Olfactory Bulb; Olfactory Pathways; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists	2005
Nuclear Ca2+ and CaM kinase IV specify hormonal- and Notch-responsiveness. Journal of neurochemistry, 2005, Volume: 93, Issue:1 Topics: 4-Aminopyridine; Aniline Compounds; Animals; Bicuculline; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cells, Cultured; Diagnostic Imaging; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fluorescent Antibody Technique; GABA Antagonists; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; Histone Deacetylases; Hormones; Hydroxamic Acids; Membrane Proteins; Neurons; Nuclear Receptor Co-Repressor 2; Okadaic Acid; Potassium Channel Blockers; Protein Synthesis Inhibitors; Receptors, Notch; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Repressor Proteins; Signal Transduction; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tretinoin; Xanthenes	2005
Electrocorticographic and deep intracerebral EEG recording in mice using a telemetry system. Brain research. Brain research protocols, 2005, Volume: 14, Issue:3 Topics: 4-Aminopyridine; Animals; Artifacts; Baclofen; Bicuculline; Brain; Electrocardiography; Electrodes, Implanted; Electroencephalography; Electromyography; GABA Agonists; GABA Antagonists; Male; Mice; Mice, Inbred C57BL; Postoperative Care; Potassium Channel Blockers; Stereotaxic Techniques; Telemetry	2005
Postnatal development of intrinsic GABAergic rhythms in mouse hippocampus. Neuroscience, 2005, Volume: 134, Issue:1 Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Periodicity; Potassium Channel Blockers	2005
Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit. Epilepsy research, 2005, Volume: 65, Issue:1-2 Topics: 4-Aminopyridine; Animals; Bicuculline; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Deletion; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; Mice; Mice, Knockout; Phosphinic Acids; Potassium Channel Blockers; Propanolamines; Pyramidal Cells; Quinolinium Compounds; Receptors, GABA-B; Time Factors; Valine	2005
GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells. Neuron, 2005, Sep-15, Volume: 47, Issue:6 Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basic Helix-Loop-Helix Transcription Factors; Bicuculline; Bromodeoxyuridine; Calbindins; Calcium; Cell Count; Cell Differentiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Green Fluorescent Proteins; Hippocampus; History, Ancient; Immunohistochemistry; In Vitro Techniques; Intermediate Filament Proteins; Ki-67 Antigen; Membrane Potentials; Mice; Mice, Transgenic; Microscopy, Immunoelectron; N-Methylaspartate; Nerve Tissue Proteins; Nestin; Neural Cell Adhesion Molecule L1; Neurons; Nickel; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Potassium Channel Blockers; S100 Calcium Binding Protein G; Sialic Acids; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Stem Cells; Tetrodotoxin; Vesicular Inhibitory Amino Acid Transport Proteins	2005
Glutamatergic regulation of the p70S6 kinase in primary mouse neurons. The Journal of biological chemistry, 2005, Nov-18, Volume: 280, Issue:46 Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Bicuculline; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dopamine; gamma-Aminobutyric Acid; Glutamine; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Norepinephrine; Peptide Elongation Factor 2; Phosphatidylinositol 3-Kinases; Phosphorylation; Potassium Channels; Protein Kinases; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Signal Transduction; Sirolimus; Synapses; Time Factors; TOR Serine-Threonine Kinases	2005
Long-range oscillatory Ca2+ waves in rat spinal dorsal horn. The European journal of neuroscience, 2005, Volume: 22, Issue:8 Topics: 4-Aminopyridine; Age Factors; Animals; Animals, Newborn; Bicuculline; Calcium; Calcium Signaling; Diagnostic Imaging; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Functional Laterality; GABA Antagonists; In Vitro Techniques; Indoles; Membrane Potentials; Nerve Net; Patch-Clamp Techniques; Posterior Horn Cells; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Spinal Cord; Statistics, Nonparametric; Strychnine; Time Factors	2005
Laminar analysis of initiation and spread of epileptiform discharges in three in vitro models. Brain research bulletin, 2006, Mar-31, Volume: 69, Issue:2 Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Convulsants; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Potentials; GABA Antagonists; Interneurons; Magnesium; Male; Neocortex; Nerve Net; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Potassium Channel Blockers; Proto-Oncogene Proteins c-fos; Pyramidal Cells; Rats; Rats, Wistar; Synaptic Transmission	2006
Different anticonvulsive effects of hesperidin and its aglycone hesperetin on electrical activity in the rat hippocampus in-vitro. The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:3 Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Bicuculline; Convulsants; Dose-Response Relationship, Drug; Drug Administration Schedule; Hesperidin; Hippocampus; In Vitro Techniques; Male; Pentylenetetrazole; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Tetraethylammonium	2006
Termination of epileptiform activity by cooling in rat hippocampal slice epilepsy models. Epilepsy research, 2006, Volume: 70, Issue:2-3 Topics: 4-Aminopyridine; Animals; Bicuculline; Cerebrospinal Fluid; Cryotherapy; Disease Models, Animal; Electrodes; Electroencephalography; Evoked Potentials; Hippocampus; Limbic System; Male; Rats; Rats, Sprague-Dawley; Seizures; Synaptic Transmission	2006
Regulation of synaptic input to hypothalamic presympathetic neurons by GABA(B) receptors. Neuroscience, 2006, Oct-13, Volume: 142, Issue:2 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Benzylamines; Bicuculline; Cadmium Chloride; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, GABA-B	2006
Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-27, Volume: 26, Issue:39 Topics: 4-Aminopyridine; Amides; Animals; Animals, Newborn; Bicuculline; Brain-Derived Neurotrophic Factor; Butadienes; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Chromones; COS Cells; Cysteine-Rich Protein 61; Gene Expression Regulation; Genes, fos; Hippocampus; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; N-Methylaspartate; Neurons; Nitriles; Potassium Chloride; Prosencephalon; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; RNA Interference; Serum Response Factor; Signal Transduction; Synaptic Transmission; Transcription Factors; Transcription, Genetic; Transfection	2006
Signaling mechanisms of angiotensin II-induced attenuation of GABAergic input to hypothalamic presympathetic neurons. Journal of neurophysiology, 2007, Volume: 97, Issue:5 Topics: 4-Aminopyridine; Analysis of Variance; Angiotensin II; Animals; Bicuculline; Deferoxamine; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Laminectomy; Male; Metalloporphyrins; Neurons, Afferent; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Potassium Channel Blockers; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Signal Transduction	2007
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Feb-07, Volume: 27, Issue:6 Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Apoptosis; Benzothiadiazines; Bicuculline; Bumetanide; Cell Size; Cells, Cultured; Cerebral Cortex; Chlorides; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glycolates; Ion Channels; Mice; Mice, Inbred C57BL; N-Methylaspartate; Necrosis; Neurons; Neurotoxins; Nitrobenzoates; Patch-Clamp Techniques; Phloretin; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Quinine; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Somatosensory Cortex; Tetrodotoxin	2007
Conductances mediating intrinsic theta-frequency membrane potential oscillations in layer II parasubicular neurons. Journal of neurophysiology, 2008, Volume: 100, Issue:5 Topics: 4-Aminopyridine; Animals; Bicuculline; Biological Clocks; Calcium Channel Blockers; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channel Blockers; Propanolamines; Pyrimidines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Tetrodotoxin; Theta Rhythm	2008
Seletracetam (ucb 44212) inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro. Epilepsia, 2009, Volume: 50, Issue:4 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Biophysics; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; GABA Antagonists; In Vitro Techniques; Levetiracetam; Magnesium; Male; Membrane Potentials; Neocortex; Neural Inhibition; Neurons; Patch-Clamp Techniques; Piracetam; Potassium Channel Blockers; Pyrrolidinones; Rats; Rats, Wistar	2009
Enhanced hypoxia susceptibility in hippocampal slices from a mouse model of rett syndrome. Journal of neurophysiology, 2009, Volume: 101, Issue:2 Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Bicuculline; Disease Models, Animal; Disease Susceptibility; Edema; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; Exons; Female; GABA Antagonists; Hippocampus; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; In Vitro Techniques; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Potassium; Potassium Channel Blockers; Quaternary Ammonium Compounds; Reaction Time; Rett Syndrome; Sex Factors	2009
Synchronous GABA-receptor-dependent potentials in limbic areas of the in-vitro isolated adult guinea pig brain. The European journal of neuroscience, 2009, Volume: 29, Issue:5 Topics: 4-Aminopyridine; Animals; Bicuculline; Cortical Spreading Depression; Cortical Synchronization; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Guinea Pigs; Inhibitory Postsynaptic Potentials; Limbic System; Neurons; Olfactory Pathways; Organ Culture Techniques; Potassium Channel Blockers; Quinoxalines; Receptors, GABA; Valine	2009
Characteristics of rostral solitary tract nucleus neurons with identified afferent connections that project to the parabrachial nucleus in rats. Journal of neurophysiology, 2009, Volume: 102, Issue:1 Topics: 4-Aminopyridine; Afferent Pathways; Amino Acids; Analysis of Variance; Animals; Bicuculline; Biophysical Phenomena; Cholera Toxin; Chorda Tympani Nerve; Electric Stimulation; GABA Antagonists; Glossopharyngeal Nerve; In Vitro Techniques; Lingual Nerve; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pons; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Synaptic Potentials; Tetraethylammonium	2009
Rebound bursts in GABAergic neurons of the thalamic reticular nucleus in postnatal mice. Physiological research, 2010, Volume: 59, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Bicuculline; Calcium-Calmodulin-Dependent Protein Kinase Type 2; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Mice; Mice, Inbred ICR; Neural Inhibition; Neurons; Organ Culture Techniques; Potassium Channel Blockers; Protein Kinase Inhibitors; Receptors, GABA-A; Thalamic Nuclei	2010
Preconditioning with 4-aminopyridine protects cerebellar granule neurons against excitotoxicity. Brain research, 2009, Oct-19, Volume: 1294 Topics: 4-Aminopyridine; Animals; Bicuculline; Cell Death; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Time Factors	2009
Suppression of the intrinsic apoptosis pathway by synaptic activity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Feb-17, Volume: 30, Issue:7 Topics: 4-Aminopyridine; Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; Bicuculline; Caspase 9; Cells, Cultured; Cerebral Cortex; Cytochromes c; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Embryo, Mammalian; Enzyme Inhibitors; GABA Antagonists; Green Fluorescent Proteins; Male; Mice; Mice, Inbred C57BL; Mutation; Neural Inhibition; Neurons; Neuroprotective Agents; Potassium Channel Blockers; Signal Transduction; Staurosporine; Synapses; Tacrolimus; Time Factors; Transfection; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Up-Regulation	2010
Characterization of voltage-gated K+ currents contributing to subthreshold membrane potential oscillations in hippocampal CA1 interneurons. Journal of neurophysiology, 2010, Volume: 103, Issue:6 Topics: 4-Aminopyridine; Animals; Animals, Newborn; Bicuculline; Biological Clocks; Biophysical Phenomena; CA1 Region, Hippocampal; Elapid Venoms; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Interneurons; Ion Channel Gating; Male; Membrane Potentials; Models, Neurological; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin	2010
The 4-aminopyridine in vitro epilepsy model analyzed with a perforated multi-electrode array. Neuropharmacology, 2011, Volume: 60, Issue:7-8 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; CA3 Region, Hippocampal; Disease Models, Animal; Electrodes; Epilepsy; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Mice; Mice, Inbred C57BL; Microarray Analysis; Motion Pictures; Piperazines; Potassium Channel Blockers; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Software; Somatosensory Cortex	2011
Cerebellar Purkinje cells fire paroxysmal depolarization shift (PDS)-like events in response to epileptogenic drugs. Neurological research, 2011, Volume: 33, Issue:1 Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Cerebellum; Convulsants; Male; Pentylenetetrazole; Purkinje Cells; Rats; Rats, Sprague-Dawley	2011
Activity-dependent regulation of surface glucose transporter-3. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Feb-09, Volume: 31, Issue:6 Topics: 4-Aminopyridine; Analysis of Variance; Animals; Bicuculline; Biotinylation; Cerebral Cortex; Cyclic GMP; Disks Large Homolog 4 Protein; Dogs; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Glucose Transporter Type 3; Green Fluorescent Proteins; Hexoses; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Potassium Channel Blockers; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptosomes; Thionucleotides; Time Factors; Transfection; Valine	2011
Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice. Neuroscience, 2011, Aug-25, Volume: 189 Topics: 4-Aminopyridine; Age Factors; Animals; Bicuculline; Brain; Convulsants; Electric Stimulation; Electroencephalography; Epilepsy; GABA-A Receptor Antagonists; Glutamate Decarboxylase; In Vitro Techniques; Mice; Mice, Knockout; Receptors, N-Methyl-D-Aspartate; Synapsins; Synaptic Transmission; Valine	2011
Spatiotemporal organization and thalamic modulation of seizures in the mouse medial thalamic-anterior cingulate slice. Epilepsia, 2011, Volume: 52, Issue:12 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Biological Clocks; Calcium; Corpus Callosum; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes; Gyrus Cinguli; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscimol; Neural Pathways; Seizures; Thalamus	2011
Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Mar-21, Volume: 32, Issue:12 Topics: 4-Aminopyridine; Analysis of Variance; Animals; Bicuculline; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Corpus Striatum; CREB-Binding Protein; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agents; Female; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Glycine Agents; Luminescent Proteins; Microfluidic Analytical Techniques; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nifedipine; Patch-Clamp Techniques; Potassium Channel Blockers; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium Channel Blockers; Strychnine; Synapses; Tetrodotoxin; Transfection; Vesicular Glutamate Transport Protein 1	2012
Epileptic stimulus increases Homer 1a expression to modulate endocannabinoid signaling in cultured hippocampal neurons. Neuropharmacology, 2012, Volume: 63, Issue:6 Topics: 4-Aminopyridine; Animals; Bicuculline; Calcium; Carrier Proteins; Cells, Cultured; Convulsants; DNA; Endocannabinoids; Epilepsy; Excitatory Postsynaptic Potentials; Hippocampus; Homer Scaffolding Proteins; Neuroimaging; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Pyridines; Rats; Real-Time Polymerase Chain Reaction; Signal Transduction; Transfection	2012
Interaction between αCaMKII and GluN2B controls ERK-dependent plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Aug-01, Volume: 32, Issue:31 Topics: 4-Aminopyridine; Analysis of Variance; Animals; Bicuculline; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Cerebral Cortex; Dendritic Spines; Disks Large Homolog 4 Protein; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Guanylate Kinases; Immunoprecipitation; In Vitro Techniques; Luminescent Proteins; Male; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neuronal Plasticity; Neurons; Phosphorylation; Photobleaching; Potassium Channel Blockers; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Transfection	2012
Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome. Neuroscience, 2013, Feb-12, Volume: 231 Topics: 4-Aminopyridine; Animals; Bicuculline; Brain Waves; Disease Models, Animal; Excitatory Amino Acid Agonists; GABA-A Receptor Antagonists; Hippocampus; Kainic Acid; Methyl-CpG-Binding Protein 2; Mice; Nerve Net; Neurons; Potassium Channel Blockers; Rett Syndrome; Seizures	2013
Rac1 and rac3 GTPases control synergistically the development of cortical and hippocampal GABAergic interneurons. Cerebral cortex (New York, N.Y. : 1991), 2014, Volume: 24, Issue:5 Topics: 4-Aminopyridine; Animals; Animals, Newborn; Bicuculline; Cell Movement; Cerebral Cortex; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; GABAergic Neurons; Gene Expression Regulation, Developmental; Hippocampus; Inhibitory Postsynaptic Potentials; Interneurons; Mice; Mice, Knockout; Piperazines; Potassium Channel Blockers; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Vesicular Inhibitory Amino Acid Transport Proteins	2014
Epileptiform stimulus increases Homer 1a expression to modulate synapse number and activity in hippocampal cultures. Journal of neurophysiology, 2013, Volume: 109, Issue:6 Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Calcium; Calcium Signaling; Carrier Proteins; Convulsants; Disks Large Homolog 4 Protein; Feedback, Physiological; Hippocampus; Homer Scaffolding Proteins; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Neurons; Potassium Channel Blockers; Protein Isoforms; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; RNA, Messenger; RNA, Small Interfering; Synapses; Transcription, Genetic	2013
Altered network communication following a neuroprotective drug treatment. PloS one, 2013, Volume: 8, Issue:1 Topics: 4-Aminopyridine; Animals; Bicuculline; Brain; Brain Mapping; Electroencephalography; Nerve Net; Neural Pathways; Neurons; Neuroprotective Agents; Rats	2013
Hippocampal hyperexcitability and specific epileptiform activity in a mouse model of Dravet syndrome. Epilepsia, 2013, Volume: 54, Issue:7 Topics: 4-Aminopyridine; Age Factors; Animals; Animals, Newborn; Bicuculline; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsies, Myoclonic; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Hippocampus; Hyperthermia, Induced; In Vitro Techniques; Kynurenic Acid; Mice; Mice, Knockout; NAV1.1 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Pyramidal Cells	2013
The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival. Molecular and cellular neurosciences, 2014, Volume: 61 Topics: 4-Aminopyridine; Animals; Astrocytes; Bicuculline; Cell Survival; Cells, Cultured; Disease Models, Animal; GABA-A Receptor Antagonists; Gene Expression Regulation; Hippocampus; Jumonji Domain-Containing Histone Demethylases; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Neurons; Pilocarpine; Potassium Channel Blockers; RNA Interference; Seizures	2014
Treatment with direct-current stimulation against cingulate seizure-like activity induced by 4-aminopyridine and bicuculline in an in vitro mouse model. Experimental neurology, 2015, Volume: 265 Topics: 4-Aminopyridine; Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Gyrus Cinguli; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Seizures; Treatment Outcome	2015
Synchronous inhibitory potentials precede seizure-like events in acute models of focal limbic seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Feb-18, Volume: 35, Issue:7 Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Computer Simulation; Convulsants; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Guinea Pigs; In Vitro Techniques; Models, Biological; Neural Inhibition; Potassium Channel Blockers; Quinoxalines; Seizures	2015
Increase in the extracellular glutamate level during seizures and electrical stimulation determined using a high temporal resolution technique. BMC neuroscience, 2015, Mar-13, Volume: 16 Topics: 4-Aminopyridine; Animals; Bicuculline; Calibration; Catheters, Indwelling; Convulsants; Dialysis; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Equipment Design; Extracellular Space; Fluorescence; Glutamic Acid; Hippocampus; Hydrogen Peroxide; Lasers; Male; Rats, Wistar; Seizures	2015
Enhanced Firing in NTS Induced by Short-Term Sustained Hypoxia Is Modulated by Glia-Neuron Interaction. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Apr-29, Volume: 35, Issue:17 Topics: 4-Aminopyridine; Action Potentials; Afferent Pathways; Amino Acids; Animals; Baroreflex; Bicuculline; Chemoreceptor Cells; GABA-A Receptor Antagonists; Heart Rate; Hypoxia; In Vitro Techniques; Male; Neuroglia; Potassium Channel Blockers; Pressoreceptors; Rats; Rats, Wistar; Solitary Nucleus; Sympathetic Nervous System	2015
Heterogeneous effects of antiepileptic drugs in an in vitro epilepsy model--a functional multineuron calcium imaging study. The European journal of neuroscience, 2015, Volume: 42, Issue:2 Topics: 4-Aminopyridine; Animals; Animals, Newborn; Anticonvulsants; Bicuculline; Calcium; Convulsants; Disease Models, Animal; Epilepsy; Evoked Potentials; Female; Hippocampus; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Statistics, Nonparametric	2015
Chronaxie Measurements in Patterned Neuronal Cultures from Rat Hippocampus. PloS one, 2015, Volume: 10, Issue:7 Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Axons; Bicuculline; Calcium; Chronaxy; Dendrites; Embryo, Mammalian; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; Potassium Channel Blockers; Primary Cell Culture; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate	2015
Failure and rescue of preconditioning-induced neuroprotection in severe stroke-like insults. Neuropharmacology, 2016, Volume: 105 Topics: 4-Aminopyridine; Animals; Aspartic Acid; Bicuculline; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Dizocilpine Maleate; Glucose; Glutamic Acid; Ischemic Preconditioning; Neurons; Neuroprotective Agents; Ouabain; Rats; Stroke; Time Factors	2016
Serine 707 of APPL1 is Critical for the Synaptic NMDA Receptor-Mediated Akt Phosphorylation Signaling Pathway. Neuroscience bulletin, 2016, Volume: 32, Issue:4 Topics: 4-Aminopyridine; Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; Bicuculline; Brain; Cells, Cultured; Disks Large Homolog 4 Protein; Embryo, Mammalian; GABA Antagonists; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Neurons; Oncogene Protein v-akt; Phosphorylation; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction	2016
2-Deoxy-d-glucose enhances tonic inhibition through the neurosteroid-mediated activation of extrasynaptic GABA Epilepsia, 2016, Volume: 57, Issue:12 Topics: 4-Aminopyridine; Animals; Antimetabolites; Antineoplastic Agents; Bicuculline; Deoxyglucose; Enzyme Inhibitors; Female; Finasteride; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glyburide; Hippocampus; Hypoglycemic Agents; In Vitro Techniques; Iodoacetates; Isoquinolines; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neural Inhibition; Neurons; Potassium Channel Blockers; Receptors, GABA; Statistics, Nonparametric	2016
Networks of Cultured iPSC-Derived Neurons Reveal the Human Synaptic Activity-Regulated Adaptive Gene Program. Cell reports, 2017, 01-03, Volume: 18, Issue:1 Topics: 4-Aminopyridine; Animals; Base Sequence; Bicuculline; Calcium Signaling; Cell Line; Cell Lineage; Cells, Cultured; Electrophysiological Phenomena; Gene Expression Regulation; Genes, Immediate-Early; Humans; Induced Pluripotent Stem Cells; Mice; Neurons; Promoter Regions, Genetic; Signal Transduction; Species Specificity; Synapses	2017
High-frequency oscillations and seizure-like discharges in the entorhinal cortex of the in vitro isolated guinea pig brain. Epilepsy research, 2017, Volume: 130 Topics: 4-Aminopyridine; Animals; Bicuculline; Convulsants; Entorhinal Cortex; Female; Guinea Pigs; In Vitro Techniques; Microelectrodes; Periodicity; Seizures	2017
Signal Transduction Underlying the Inhibitory Mechanism of Fluoxetine on Electrical Field Stimulation Response in Rat Ileal Smooth Muscle. Pharmacology, 2017, Volume: 99, Issue:5-6 Topics: 4-Aminopyridine; Amides; Animals; Atropine; Azepines; Benzophenanthridines; Bicuculline; Calcimycin; Drug Interactions; Electric Stimulation; Estrenes; Fluoxetine; Glyburide; Ileum; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Ondansetron; Pyridines; Pyrrolidinones; Rats; Signal Transduction; Sulfonamides; Tetraethylammonium	2017
Study on the mechanisms of seizure-like events suppression effect by electrical stimulation using a microelectrode array. Neuroreport, 2017, Jun-14, Volume: 28, Issue:9 Topics: 4-Aminopyridine; Animals; Animals, Newborn; Bicuculline; Biophysics; Cerebral Cortex; Convulsants; Electric Stimulation; Long-Term Synaptic Depression; Male; Microelectrodes; Neurons; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley	2017
Zinc mediates the neuronal activity-dependent anti-apoptotic effect. PloS one, 2017, Volume: 12, Issue:8 Topics: 4-Aminopyridine; Animals; Apoptosis; Bicuculline; Caspase 3; Cell Survival; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Hippocampus; Male; Neurons; Neuroprotection; Neuroprotective Agents; Rats, Sprague-Dawley; Staurosporine; Synaptic Transmission; Tissue Culture Techniques; Zinc	2017
Glycinergic neurotransmission in the rostral ventrolateral medulla controls the time course of baroreflex-mediated sympathoinhibition. The Journal of physiology, 2019, Volume: 597, Issue:1 Topics: 4-Aminopyridine; Animals; Baroreflex; Bicuculline; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Inhibitory Postsynaptic Potentials; Male; Medulla Oblongata; Muscimol; Neural Inhibition; Neurons; Potassium Channel Blockers; Rats, Sprague-Dawley; Strychnine; Sympathetic Nervous System; Synaptic Transmission; Tetrodotoxin	2019
AMP-activated Protein Kinase Controls Immediate Early Genes Expression Following Synaptic Activation Through the PKA/CREB Pathway. International journal of molecular sciences, 2018, Nov-22, Volume: 19, Issue:12 Topics: 4-Aminopyridine; Adenylyl Cyclases; AMP-Activated Protein Kinases; Animals; Bicuculline; Cell Differentiation; CREB-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Early Growth Response Protein 1; Embryo, Mammalian; Gene Expression Regulation, Developmental; Genes, Immediate-Early; Memory, Long-Term; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Primary Cell Culture; Prosencephalon; Proto-Oncogene Proteins c-fos; Synaptic Transmission	2018
Spreading depression as an innate antiseizure mechanism. Nature communications, 2021, 04-13, Volume: 12, Issue:1 Topics: 4-Aminopyridine; Animals; Bicuculline; Brain Stem; Cortical Spreading Depression; Depression; Female; Gene Knock-In Techniques; Kainic Acid; Male; Mice; Nervous System; Optogenetics; Penicillins; Potassium Channel Blockers; Seizures; Tetrodotoxin	2021
Long Noncoding RNA Expression Profiles of Rat Extrasynaptic and Synaptic Neurons Expressing the N-methyl-D-Aspartate Receptor Revealed by Microarray Analysis. World neurosurgery, 2021, Volume: 153 Topics: 4-Aminopyridine; Animals; Bicuculline; Cerebral Cortex; Down-Regulation; Excitatory Amino Acid Agonists; GABA-A Receptor Antagonists; Glycine; Glycine Agents; Microarray Analysis; N-Methylaspartate; Neurons; Polymerase Chain Reaction; Potassium Channel Blockers; Primary Cell Culture; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Long Noncoding; Synapses; Up-Regulation	2021
Excitatory-inhibitory mismatch shapes node recruitment in an epileptic network. Epilepsia, 2023, Volume: 64, Issue:7 Topics: 4-Aminopyridine; Animals; Bicuculline; Brain; Brain Mapping; Epilepsy	2023