bicalutamide and tamoxifen

bicalutamide has been researched along with tamoxifen in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.88)18.2507
2000's12 (35.29)29.6817
2010's18 (52.94)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Azizi, B; Doyle, DF; Gryder, BE; Johnson, KA; Oyelere, AK; Patil, V; Raftery, ED; Rice, M; Rood, MK; Yao, LP1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Wakeling, AE1
Richie, JP1
Battaglia, M; Bertaccini, A; Boccardo, F; Comeri, G; Conti, G; Di Tonno, P; Durand, F; Ferraris, V; Galassi, P; Macchiarella, A; Manganelli, A; Martorana, G; Montefiore, F; Muscas, G; Potenzoni, D; Rubagotti, A; Selvaggi, FP; Siragusa, A; Zattoni, F1
Gallo, J; Morris, T; Saltzstein, D; Sieber, P1
Boccardo, F; Conti, G; Del Monaco, D; Manganelli, A; Potenzoni, D; Rubagotti, A1
Autorino, R; Bianco, AR; D'Armiento, M; Damiano, R; De Placido, S; De Sio, M; Di Lorenzo, G; Gallo, A; Gallo, L; Perdonà, S; Pingitore, D1
Thönnessen, D; Wenz, F1
Autorino, R; D'Armiento, M; Damiano, R; De Placido, S; De Sio, M; Di Lorenzo, G; Gallo, A; Gallo, L; Perdonà, S; Pingitore, D1
Andersen, M; Armstrong, J; Egerdie, B; Fradet, Y; Morris, T; Nachabe, M; Navani, S; Tammela, TL1
Van Poppel, H1
Dawkins, GP; Harris, JP; Nuttall, MC1
Sieber, PR1
Aragona, F; Bedognetti, D; Boccardo, F; Canclini, L; Conti, G; Cortellini, P; De Cobelli, O; Di Tonno, P; Francesca, F; Gallucci, M; Lapini, A; Martorana, G; Rubagotti, A1
Balbi, C; Barboro, P; Boccardo, F; Ferrari, N; Repaci, E; Rubagotti, A1
Allegro, R; Altieri, V; De Grande, G; Ferraù, F; Gebbia, V; Mazza, R; Melloni, D; Morgia, G; Nicolosi, F; Serretta, V1
Garcia, PL; Gomes, FP1
Argellati, F; Boccardo, F; Mangerini, R; Pfeffer, U1
Alfaro, IE; Bernales, S; Cittelly, DM; Cochrane, DR; D'Amato, NC; Edgerton, SM; Elias, AD; Gómez, F; Guerrero, J; Howe, EN; Jacobsen, BM; Jean, A; Jedlicka, P; McCullagh, E; Medicherla, S; Protter, AA; Richer, JK; Spoelstra, NS; Thor, AD; Torkko, KC1
Bevan, CL; Brooke, GN; Fioretti, FM; Sita-Lumsden, A1
Baumgarten, L; Dabaja, AA1
Beijnen, JH; de Jong, KAM; de Vries, N; Rosing, H; van Nuland, M; Venekamp, N1
Aebersold, DM; Albrecht, C; Böhmer, D; Flentje, M; Ganswindt, U; Ghadjar, P; Höcht, S; Hölscher, T; Müller, AC; Niehoff, P; Pinkawa, M; Sedlmayer, F; Wiegel, T; Zips, D1
Cao, J; Du, X; Liang, Z; Peng, Y; Shi, J; Tian, L; Yang, K; Zhang, J1

Reviews

7 review(s) available for bicalutamide and tamoxifen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Steroid antagonists as nuclear receptor blockers.
    Cancer surveys, 1992, Volume: 14

    Topics: Androgen Antagonists; Anilides; Animals; Estradiol; Estrogen Antagonists; Estrogens; Humans; Mifepristone; Nitriles; Polyunsaturated Alkamides; Rats; Receptors, Estrogen; Tamoxifen; Tosyl Compounds

1992
Anti-androgens and other hormonal therapies for prostate cancer.
    Urology, 1999, Volume: 54, Issue:6A Suppl

    Topics: Androgen Antagonists; Androgens; Anilides; Biomarkers, Tumor; Flutamide; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds

1999
Treatment of bicalutamide-induced breast events.
    Expert review of anticancer therapy, 2007, Volume: 7, Issue:12

    Topics: Androgen Antagonists; Anilides; Clinical Trials as Topic; Estrogen Receptor Modulators; Gynecomastia; Humans; Male; Nitriles; Pain; Pain Management; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds

2007
Revising the role of the androgen receptor in breast cancer.
    Journal of molecular endocrinology, 2014, Volume: 52, Issue:3

    Topics: Abiraterone Acetate; Androgen Antagonists; Androgens; Androstadienes; Anilides; Estrogen Antagonists; Female; Humans; Nitriles; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Steroid 17-alpha-Hydroxylase; Tamoxifen; Tosyl Compounds; Triple Negative Breast Neoplasms

2014
Diagnosis and Management of Gynecomastia for Urologists.
    Current urology reports, 2018, May-17, Volume: 19, Issue:7

    Topics: Androgen Antagonists; Anilides; Estrogen Antagonists; Gynecomastia; Humans; Male; Nitriles; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds

2018
Treatment strategies to prevent and reduce gynecomastia and/or breast pain caused by antiandrogen therapy for prostate cancer : Statement from the DEGRO working group prostate cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:7

    Topics: Adenocarcinoma; Anastrozole; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Dizziness; Dose Fractionation, Radiation; Drug Administration Schedule; Estrogen Receptor Modulators; Flushing; Gynecomastia; Humans; Male; Mastodynia; Meta-Analysis as Topic; Neoplasms, Hormone-Dependent; Nitriles; Off-Label Use; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Tamoxifen; Tosyl Compounds

2020

Trials

8 trial(s) available for bicalutamide and tamoxifen

ArticleYear
Evaluation of tamoxifen and anastrozole in the prevention of gynecomastia and breast pain induced by bicalutamide monotherapy of prostate cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Feb-01, Volume: 23, Issue:4

    Topics: Aged; Aged, 80 and over; Anastrozole; Anilides; Breast Diseases; Double-Blind Method; Gynecomastia; Humans; Male; Middle Aged; Nitriles; Pain; Prostate-Specific Antigen; Prostatic Neoplasms; Quality of Life; Tamoxifen; Testosterone; Tosyl Compounds; Triazoles

2005
Prevention and management of bicalutamide-induced gynecomastia and breast pain: randomized endocrinologic and clinical studies with tamoxifen and anastrozole.
    Prostate cancer and prostatic diseases, 2005, Volume: 8, Issue:1

    Topics: Aged; Aged, 80 and over; Anastrozole; Anilides; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Diseases; Double-Blind Method; Gynecomastia; Humans; Male; Middle Aged; Nitriles; Pain; Placebos; Prostatic Neoplasms; Tamoxifen; Testosterone; Tosyl Compounds; Treatment Outcome; Triazoles

2005
Exploratory study of drug plasma levels during bicalutamide 150 mg therapy co-administered with tamoxifen or anastrozole for prophylaxis of gynecomastia and breast pain in men with prostate cancer.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:4

    Topics: Aged; Aged, 80 and over; Anastrozole; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Interactions; Gynecomastia; Humans; Male; Middle Aged; Nitriles; Pain; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds; Triazoles

2005
Efficacy of tamoxifen and radiotherapy for prevention and treatment of gynaecomastia and breast pain caused by bicalutamide in prostate cancer: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:5

    Topics: Aged; Androgen Antagonists; Anilides; Antineoplastic Agents; Combined Modality Therapy; Disease-Free Survival; Estrogen Antagonists; Gynecomastia; Humans; Male; Middle Aged; Nitriles; Pain; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds

2005
Gynecomastia and breast pain induced by adjuvant therapy with bicalutamide after radical prostatectomy in patients with prostate cancer: the role of tamoxifen and radiotherapy.
    The Journal of urology, 2005, Volume: 174, Issue:6

    Topics: Aged; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Chemotherapy, Adjuvant; Disease-Free Survival; Estrogen Receptor Modulators; Follow-Up Studies; Gynecomastia; Humans; Male; Middle Aged; Nitriles; Pain; Penile Erection; Prospective Studies; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Quality of Life; Radiotherapy, Adjuvant; Severity of Illness Index; Tamoxifen; Testosterone; Time Factors; Tosyl Compounds; Treatment Outcome

2005
Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study.
    European urology, 2007, Volume: 52, Issue:1

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Dose-Response Relationship, Drug; Double-Blind Method; Estrogen Antagonists; Follow-Up Studies; Gynecomastia; Humans; Incidence; Male; Middle Aged; Neoplasm Staging; Nitriles; Pain; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds; Treatment Outcome

2007
An open, randomised, multicentre, phase 3 trial comparing the efficacy of two tamoxifen schedules in preventing gynaecomastia induced by bicalutamide monotherapy in prostate cancer patients.
    European urology, 2010, Volume: 57, Issue:2

    Topics: Aged; Anilides; Antineoplastic Agents; Drug Administration Schedule; Estrogen Antagonists; Gynecomastia; Humans; Male; Middle Aged; Nitriles; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds

2010
A randomized trial comparing tamoxifen therapy vs. tamoxifen prophylaxis in bicalutamide-induced gynecomastia.
    Clinical genitourinary cancer, 2012, Volume: 10, Issue:3

    Topics: Aged; Aged, 80 and over; Anilides; Antineoplastic Agents; Chemotherapy, Adjuvant; Estrogen Antagonists; Gynecomastia; Humans; Male; Middle Aged; Nitriles; Prostatic Neoplasms; Statistics, Nonparametric; Tamoxifen; Tosyl Compounds; Treatment Outcome

2012

Other Studies

19 other study(ies) available for bicalutamide and tamoxifen

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Histone deacetylase inhibitors equipped with estrogen receptor modulation activity.
    Journal of medicinal chemistry, 2013, Jul-25, Volume: 56, Issue:14

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Drug Discovery; Estrogen Receptor Modulators; Histone Deacetylase Inhibitors; Humans; Molecular Docking Simulation; Receptors, Estrogen; Structure-Activity Relationship

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Radiotherapeutic prophylaxis of gynecomastia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Anastrozole; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Gynecomastia; Humans; Male; Nitriles; Pain; Prostatic Neoplasms; Quality of Life; Tamoxifen; Tosyl Compounds; Triazoles

2005
Editorial comment on: Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study.
    European urology, 2007, Volume: 52, Issue:1

    Topics: Androgen Antagonists; Anilides; Dose-Response Relationship, Drug; Estrogen Antagonists; Follow-Up Studies; Gynecomastia; Humans; Male; Nitriles; Pain; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds; Treatment Outcome

2007
The role of tamoxifen in reducing bicalutamide-induced gynaecomastia and breast pain.
    BJU international, 2007, Volume: 99, Issue:2

    Topics: Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Gynecomastia; Humans; Male; Nitriles; Pain; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds; Treatment Outcome

2007
Androgen receptor and heterogeneous nuclear ribonucleoprotein K colocalize in the nucleoplasm and are modulated by bicalutamide and 4-hydroxy-tamoxifen in prostatic cancer cell lines.
    The Prostate, 2011, Sep-15, Volume: 71, Issue:13

    Topics: Androgen Antagonists; Anilides; Cell Line, Tumor; Cell Nucleus; Cell Survival; Estrogen Antagonists; Heterogeneous-Nuclear Ribonucleoprotein K; Humans; Male; Nitriles; Phosphorylation; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Tamoxifen; Tosyl Compounds

2011
Development and validation of a simple and sensitive high performance liquid chromatographic method for the simultaneous determination of anastrozole, bicalutamide, tamoxifen, and their synthetic impurities.
    Talanta, 2012, Nov-15, Volume: 101

    Topics: Analysis of Variance; Anastrozole; Anilides; Calibration; Chromatography, High Pressure Liquid; Limit of Detection; Nitriles; Reproducibility of Results; Tamoxifen; Tosyl Compounds; Triazoles

2012
Effects of bicalutamide and 4OH-tamoxifen on androgen-regulated gene expression in the LNCaP cell line.
    Anticancer research, 2012, Volume: 32, Issue:12

    Topics: Androgens; Anilides; Antineoplastic Combined Chemotherapy Protocols; Cell Growth Processes; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds

2012
Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide.
    Breast cancer research : BCR, 2014, Jan-22, Volume: 16, Issue:1

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Animals; Antineoplastic Agents, Hormonal; Apoptosis; Benzamides; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease-Free Survival; Estrogen Receptor alpha; Female; Humans; MCF-7 Cells; Mice; Middle Aged; Neoplasm Transplantation; Nitriles; Phenylthiohydantoin; Receptors, Androgen; Signal Transduction; Tamoxifen; Tosyl Compounds; Transplantation, Heterologous

2014
Development and validation of an UPLC-MS/MS method for the therapeutic drug monitoring of oral anti-hormonal drugs in oncology.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, Feb-01, Volume: 1106-1107

    Topics: Administration, Oral; Anastrozole; Androstadienes; Androstenes; Anilides; Antineoplastic Agents, Hormonal; Benzamides; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Nitriles; Phenylthiohydantoin; Tamoxifen; Tandem Mass Spectrometry; Tosyl Compounds

2019
The ERα-NRF2 signalling axis promotes bicalutamide resistance in prostate cancer.
    Cell communication and signaling : CCS, 2022, 11-14, Volume: 20, Issue:1

    Topics: Cell Line, Tumor; Estrogen Receptor alpha; Estrogens; Gene Expression Regulation, Neoplastic; Humans; Male; NF-E2-Related Factor 2; Prostatic Neoplasms, Castration-Resistant; Tamoxifen

2022