bicalutamide has been researched along with metribolone in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (12.20) | 18.2507 |
| 2000's | 16 (39.02) | 29.6817 |
| 2010's | 18 (43.90) | 24.3611 |
| 2020's | 2 (4.88) | 2.80 |
| Authors | Studies |
|---|---|
| Allan, GF; Li, X; Lundeen, SG; Musto, A; Sui, Z; Zhang, X | 1 |
| Chang, CY; Hanson, RN; McDonnell, DP; Weiser, PT; Williams, AB | 1 |
| Bian, J; Chen, R; Li, M; Li, Z; Tang, J; Tian, Y; Xie, Y; Xu, X; Zhang, Y; Zhang, Z | 1 |
| Wang, S; Xiang, W | 1 |
| Bartsch, G; Cronauer, MV; Culig, Z; Hittmair, A; Hobisch, A; Klocker, H; Radmayr, C; Trapman, J | 1 |
| Berrevoets, CA; Mulder, E; Veldscholte, J | 1 |
| Esquenet, M; Goossens, K; Heyns, W; Swinnen, JV; Verhoeven, G | 1 |
| Jimenez, J; Luizzi, MF; Sonnenschein, C; Soto, AM; Szelei, J | 1 |
| Bartsch, G; Cronauer, MV; Culig, Z; Hittmair, A; Hobisch, A; Klocker, H; Radmayr, C; Zhang, J | 1 |
| Lumbroso, S; Moras, D; Nicolas, JC; Poujol, N; Sultan, C; Tahiri, B; Wurtz, JM | 1 |
| Shain, SA | 1 |
| Bjeldanes, LF; Firestone, GL; Le, HT; Schaldach, CM | 1 |
| De Marzo, AM; Denis, S; Ewing, CM; Ferdinandusse, S; Isaacs, WB; Luo, J; Wanders, RJ; Zha, S | 1 |
| Bartsch, G; Comuzzi, B; Culig, Z; Hobisch, A; Jasarevic, Z; Lodde, M; Nemes, C; Offner, F; Pycha, A; Schmidt, S | 1 |
| Chuu, CP; Dang, M; Fukuchi, J; Hiipakka, RA; Hsu, S; Kokontis, JM; Liao, S | 1 |
| Farla, P; Hersmus, R; Houtsmuller, AB; Trapman, J | 1 |
| Agoulnik, IU; Mancini, MA; Marcelli, M; Mikic, I; Moran, T; Price, JH; Simeoni, S; Stenoien, DL; Szafran, AT; Weigel, NL | 1 |
| Chen, Y; Godfrey, B; Kokontis, J; Liao, S; Lin, A; Lin, Y; Tang, F; Xiang, J | 1 |
| Leung, HY; Robson, JL; Rowland, JG; Simon, WJ; Slabas, AR | 1 |
| Chang, CY; Elbi, C; Hager, GL; Hendarwanto, A; Klokk, TI; Kurys, P; Nagaich, AK; Saatcioglu, F; Slagsvold, T | 1 |
| Heer, R; Leung, HY; Robson, CN; Shenton, BK | 1 |
| Bidaisee, LA; Bryskine, I; Gupta, RS; Lin, H; Lu, JP; Pinthus, JH; Singh, G | 1 |
| Jääskeläinen, T; Kauhanen, M; Makkonen, H; Paakinaho, V; Palvimo, JJ | 1 |
| Bryskin, I; Hou, ZF; Lu, JP; Monardo, L; Pinthus, JH; Trachtenberg, J; Wilson, BC | 1 |
| Cavarretta, IT; Culig, Z; Hobisch, A; Mitterberger, M; Neuwirt, H; Puhr, M | 1 |
| Desiniotis, A; Eder, IE; Klocker, H; Schäfer, G | 1 |
| Jääskeläinen, T; Kauhanen, M; Makkonen, H; Palvimo, JJ | 1 |
| Bryskin, I; Laflamme, P; Lin, H; Lu, JP; Monardo, L; Pinthus, JH; Qiao, S; Shayegan, B; Singh, G; Wilson, BC | 1 |
| Foley, R; Hollywood, D; Keane, JP; Lynch, TH; Marignol, L | 1 |
| Cowan, NJ; Djouder, N; Garabedian, MJ; Ha, S; Logan, SK; Mita, P; Nwachukwu, JC; Ruoff, R; Savas, JN; Schafler, ED; Tanese, N; Yates, JR; Zavadil, J | 1 |
| Chuu, CP; Fukuchi, J; Hiipakka, RA; Huo, C; Kokontis, JM; Liao, S; Lin, CY; Lin, HP; Su, LC | 1 |
| Heer, R | 1 |
| Abukhdeir, AM; Argani, P; Cosgrove, DP; De Marzo, AM; Garay, JP; Gustin, JP; Higgins, MJ; Jelovac, D; Karakas, B; Konishi, H; Konishi, Y; Lauring, J; Lewis, G; Meeker, A; Mohseni, M; Morin, PJ; Park, BH; Sherman Baust, CA; Subhawong, A; Toubaji, A; Wang, GM; Weeraratna, A | 1 |
| Antony, L; Chen, S; D'Antonio, JM; Dalrymple, SP; Denmeade, SR; Isaacs, JT; Luo, J; Ndikuyeze, GH | 1 |
| Arlt, W; Attard, G; Carreira, S; de Bono, JS; Goodall, J; Hay, CW; Lim, AC; McEwan, IJ; Nowakowska, K; Pezaro, C; Richards, J; Taylor, AE; Wingate, A | 1 |
| Cherian, MT; Shapiro, DJ; Wilson, EM | 1 |
| Bazarov, A; Broderick, CJ; Eisermann, K; Fraizer, GC; Moazam, MM | 1 |
| Cao, Q; Gong, Y; Gu, J; He, Z; Nie, H; Zhu, L | 1 |
| Arthur Chen, YM; Chang, TJ; Chou, KH; Huang, YZ; Lee, CM; Tzeng, TY; Yen, CH | 1 |
| Bai, X; Danielpour, D; Montano, MM; Song, K; Wittmann, BM; Yeh, IJ | 1 |
| Coleman, I; Nelson, PS; Nolley, R; Peehl, DM; Saar, M; Vessella, RL; Young, SR; Zhao, H | 1 |
2 review(s) available for bicalutamide and metribolone
| Article | Year |
|---|---|
Overview of the development of selective androgen receptor modulators (SARMs) as pharmacological treatment for osteoporosis (1998-2021).
Topics: Androgen Antagonists; Androgens; Humans; Osteoporosis; Receptors, Androgen; Structure-Activity Relationship | 2022 |
Therapeutic Strategies to Target the Androgen Receptor.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2022 |
39 other study(ies) available for bicalutamide and metribolone
| Article | Year |
|---|---|
Discovery of indole-containing tetracycles as a new scaffold for androgen receptor ligands.
Topics: Androgen Receptor Antagonists; Animals; Cell Line; Cyclization; Indoles; Ligands; Mice; Molecular Structure; Rats; Receptors, Androgen; Structure-Activity Relationship | 2006 |
3,3'-Disubstituted bipolar biphenyls as inhibitors of nuclear receptor coactivator binding.
Topics: Binding Sites; Binding, Competitive; Biphenyl Compounds; Cell Line, Tumor; Estrogen Receptor alpha; Female; Humans; Molecular Structure; Nuclear Receptor Coactivator 2; Nuclear Receptor Coactivators; Protein Binding | 2012 |
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor.
Topics: Androgen Antagonists; Anilides; Chloramphenicol O-Acetyltransferase; Epidermal Growth Factor; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Genes, Reporter; Growth Substances; Humans; Insulin-Like Growth Factor I; Male; Metribolone; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tosyl Compounds; Transfection; Tumor Cells, Cultured | 1994 |
Effects of antiandrogens on transformation and transcription activation of wild-type and mutated (LNCaP) androgen receptors.
Topics: Adenocarcinoma; Alanine; Amino Acid Sequence; Androgen Antagonists; Anilides; Animals; Blotting, Western; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cyproterone Acetate; Dose-Response Relationship, Drug; Flutamide; Humans; Male; Metribolone; Mutagenesis, Site-Directed; Nitriles; Point Mutation; Prostatic Neoplasms; Receptors, Androgen; Recombinant Proteins; Threonine; Tosyl Compounds; Transcription, Genetic; Transfection; Transformation, Genetic; Tumor Cells, Cultured | 1993 |
Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP.
Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme Induction; Fatty Acid Synthases; Gene Expression Regulation, Neoplastic; Humans; Lipids; Male; Metribolone; Nandrolone; Neoplasm Proteins; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Testosterone Congeners; Tosyl Compounds; Tumor Cells, Cultured | 1997 |
Androgen-induced inhibition of proliferation in human breast cancer MCF7 cells transfected with androgen receptor.
Topics: Androgen Antagonists; Androgens; Anilides; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Flutamide; Humans; In Vitro Techniques; Metribolone; Nandrolone; Nitriles; Receptors, Androgen; Testosterone; Testosterone Congeners; Tosyl Compounds; Transfection; Tumor Cells, Cultured | 1997 |
Synergistic activation of androgen receptor by androgen and luteinizing hormone-releasing hormone in prostatic carcinoma cells.
Topics: Androgen Antagonists; Anilides; Bucladesine; Cell Line; Chloramphenicol O-Acetyltransferase; Cyclic AMP; Flutamide; Genes, Reporter; Gonadotropin-Releasing Hormone; Humans; Kinetics; Male; Metribolone; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Recombinant Fusion Proteins; Testosterone Congeners; Tosyl Compounds; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1997 |
Specific recognition of androgens by their nuclear receptor. A structure-function study.
Topics: Amino Acid Sequence; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Binding Sites; Computer Simulation; Cyproterone Acetate; Dose-Response Relationship, Drug; Flutamide; Humans; Ligands; Metribolone; Models, Molecular; Molecular Sequence Data; Nitriles; Progesterone; Promegestone; Receptors, Androgen; Sequence Alignment; Tosyl Compounds; Transcriptional Activation | 2000 |
Neither fibroblast growth factor-1 nor fibroblast growth factor-2 is an androgen receptor coactivator in androgen-resistant prostate cancer.
Topics: Androgen Antagonists; Anilides; Animals; Cell Division; Cell Survival; Culture Media, Serum-Free; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Imidazoles; Imidazolidines; Male; Metribolone; Nitriles; Prostatic Neoplasms; Rats; Receptors, Androgen; Testosterone Congeners; Tosyl Compounds; Transfection; Tumor Cells, Cultured | 2001 |
Plant-derived 3,3'-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells.
Topics: Adenocarcinoma; Androgen Antagonists; Anilides; Animals; Anticarcinogenic Agents; Binding, Competitive; Cell Division; Cell Nucleus; Cytoplasm; Dihydrotestosterone; DNA; Gene Expression Regulation, Neoplastic; Indoles; Male; Metribolone; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Signal Transduction; Testosterone Congeners; Tosyl Compounds; Transcription, Genetic; Tumor Cells, Cultured; Vegetables | 2003 |
Alpha-methylacyl-CoA racemase as an androgen-independent growth modifier in prostate cancer.
Topics: Androgen Antagonists; Androgens; Anilides; Cell Division; Cell Line, Tumor; Humans; Male; Metribolone; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Racemases and Epimerases; Receptors, Androgen; RNA, Small Interfering; Testosterone Congeners; Tosyl Compounds; Transfection | 2003 |
The androgen receptor co-activator CBP is up-regulated following androgen withdrawal and is highly expressed in advanced prostate cancer.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Cell Line, Tumor; CREB-Binding Protein; Down-Regulation; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Insulin-Like Growth Factor I; Interleukin-6; Male; Metribolone; Nitriles; Nuclear Proteins; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; RNA, Neoplasm; Tosyl Compounds; Trans-Activators; Tyrphostins; Up-Regulation | 2004 |
Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity.
Topics: Androgen Antagonists; Androgens; Anilides; Animals; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Disease Progression; Humans; Intracellular Signaling Peptides and Proteins; Male; Metribolone; Mice; Mice, Inbred BALB C; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone; Tosyl Compounds | 2005 |
Antiandrogens prevent stable DNA-binding of the androgen receptor.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Computer Simulation; DNA; DNA-Binding Proteins; DNA, Neoplasm; Flutamide; Green Fluorescent Proteins; Humans; Liver Neoplasms; Male; Metribolone; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Recombinant Fusion Proteins; Tosyl Compounds | 2005 |
Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility.
Topics: Active Transport, Cell Nucleus; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Cell Nucleus; Dose-Response Relationship, Drug; HeLa Cells; Humans; Ligands; Metribolone; Microscopy, Fluorescence; Nitriles; Protein Structure, Tertiary; Receptors, Androgen; Tosyl Compounds | 2006 |
Androgen and its receptor promote Bax-mediated apoptosis.
Topics: Androgen Antagonists; Androgens; Anilides; Apoptosis; bcl-2-Associated X Protein; Humans; Male; Metribolone; Mitochondria; Nitriles; Prostatic Neoplasms; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Receptors, Androgen; Tosyl Compounds; Transcription, Genetic; Tumor Cells, Cultured; Ultraviolet Rays | 2006 |
Evaluation of an in vitro model of androgen ablation and identification of the androgen responsive proteome in LNCaP cells.
Topics: Androgens; Anilides; Cell Line, Tumor; Electrophoresis, Gel, Two-Dimensional; Gene Expression; Humans; Male; Metribolone; Nitriles; Prostatic Neoplasms; Proteome; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tosyl Compounds | 2007 |
Ligand-specific dynamics of the androgen receptor at its response element in living cells.
Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Animals; Cell Line, Tumor; Chromatin Assembly and Disassembly; Cyproterone Acetate; Dihydrotestosterone; Female; Fluorescence Recovery After Photobleaching; Flutamide; Genes, Reporter; Green Fluorescent Proteins; In Situ Hybridization, Fluorescence; Ligands; Luciferases; Mammary Neoplasms, Animal; Mammary Tumor Virus, Mouse; Metribolone; Mice; Microscopy, Video; Mifepristone; Models, Biological; Nitriles; Plasmids; Promoter Regions, Genetic; Receptors, Androgen; Response Elements; Testosterone; Tosyl Compounds; Transcription, Genetic | 2007 |
The role of androgen in determining differentiation and regulation of androgen receptor expression in the human prostatic epithelium transient amplifying population.
Topics: AC133 Antigen; Acid Phosphatase; Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antigens, CD; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblast Growth Factor 7; Glycoproteins; Humans; Integrin alpha2beta1; Keratin-18; Leupeptins; Male; Metribolone; Middle Aged; Neoplastic Stem Cells; Nitriles; Peptides; Phenotype; Prostate-Specific Antigen; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Tyrosine Phosphatases; Receptors, Androgen; RNA, Messenger; Signal Transduction; Testosterone Congeners; Tosyl Compounds | 2007 |
Androgen-dependent regulation of medium and long chain fatty acids uptake in prostate cancer.
Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Aspartate Aminotransferase, Mitochondrial; Blotting, Western; Cell Line, Tumor; Fatty Acid-Binding Proteins; Fatty Acids; Flow Cytometry; Humans; Male; Metribolone; Microscopy, Confocal; Neoplasms, Hormone-Dependent; Nitriles; Oleic Acid; Prostatic Neoplasms; Tosyl Compounds; Up-Regulation | 2007 |
Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers.
Topics: Androgen Antagonists; Anilides; Binding Sites; Cell Line, Tumor; Chromatin; Chromatin Assembly and Disassembly; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Introns; Male; Metribolone; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Tacrolimus Binding Proteins; Testosterone Congeners; Tosyl Compounds; Transcription, Genetic; Transcriptional Activation | 2009 |
Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase.
Topics: Acetophenones; Acetylcysteine; Androgen Antagonists; Androgens; Anilides; Animals; Cell Line, Tumor; Humans; Male; Membrane Glycoproteins; Metribolone; Mice; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Neoplasm Transplantation; Nitriles; Onium Compounds; Oxidative Stress; Prostatic Neoplasms; Radiation-Sensitizing Agents; Reactive Oxygen Species; Tosyl Compounds | 2010 |
[Androgens stimulate the expression of SOCS-3 and inhibits their effect on proliferation and secretion].
Topics: Androgen Antagonists; Androgens; Anilides; Biomarkers, Tumor; Blotting, Western; Cell Division; Cyclin-Dependent Kinases; Doxycycline; Gene Expression; Humans; Interleukin-6; Male; Metribolone; Nitriles; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; RNA, Messenger; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Testosterone Congeners; Tosyl Compounds; Transfection; Tumor Cells, Cultured | 2009 |
Enhanced antiproliferative and proapoptotic effects on prostate cancer cells by simultaneously inhibiting androgen receptor and cAMP-dependent protein kinase A.
Topics: Adenocarcinoma; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Animals; Apoptosis; Bucladesine; Cell Division; Colforsin; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Enzyme Induction; Gene Knockdown Techniques; Humans; Isoquinolines; Male; Metribolone; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; RNA, Small Interfering; Signal Transduction; Sulfonamides; Tosyl Compounds | 2010 |
Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells.
Topics: Androgens; Anilides; Cell Line, Tumor; Chromatin; Cyproterone Acetate; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Metribolone; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Transcription, Genetic | 2011 |
Inter-related in vitro effects of androgens, fatty acids and oxidative stress in prostate cancer: a mechanistic model supporting prevention strategies.
Topics: Androgen Antagonists; Anilides; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Fatty Acids; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Humans; Male; Metribolone; Mitochondria; Neoplasms, Hormone-Dependent; Nitriles; Oxidation-Reduction; Oxidative Stress; Prostatic Neoplasms; Reactive Oxygen Species; RNA, Messenger; Testosterone Congeners; Tosyl Compounds; Uncoupling Agents; Up-Regulation | 2010 |
Comment on "Androgen-hypersensitive preclinical model of prostate cancer" by Kawata et al.
Topics: Androgen Antagonists; Anilides; Animals; Cell Line, Tumor; Cell Proliferation; Clinical Trials as Topic; Male; Metribolone; Mice; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Tosyl Compounds | 2011 |
Regulation of androgen receptor-mediated transcription by RPB5 binding protein URI/RMP.
Topics: Androgen Antagonists; Anilides; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Immunoprecipitation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HEK293 Cells; Homeodomain Proteins; Humans; Intracellular Signaling Peptides and Proteins; Male; Metribolone; Molecular Chaperones; Neoplasm Proteins; Nitriles; Oligonucleotide Array Sequence Analysis; Phosphorylation; Prostatic Neoplasms; Protein Binding; Receptors, Androgen; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tosyl Compounds; Transcription Factors; Transcription, Genetic | 2011 |
Androgen suppresses proliferation of castration-resistant LNCaP 104-R2 prostate cancer cells through androgen receptor, Skp2, and c-Myc.
Topics: Adenocarcinoma; Androgen Antagonists; Anilides; Animals; Cell Cycle; Cell Division; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Drug Implants; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Male; Metribolone; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Nitriles; Orchiectomy; Prostatic Neoplasms; Proto-Oncogene Proteins c-myc; Receptors, Androgen; S-Phase Kinase-Associated Proteins; Testosterone; Tosyl Compounds; Xenograft Model Antitumor Assays | 2011 |
Hunterian Lecture. Characterisation of human prostate epithelial progenitor differentiation in response to androgens.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Antigens, Differentiation; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cysteine Proteinase Inhibitors; Epithelial Cells; Humans; Leupeptins; Male; Metribolone; Middle Aged; Neoplastic Stem Cells; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Testosterone Congeners; Tosyl Compounds | 2011 |
The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation.
Topics: Androgen Antagonists; Androgens; Anilides; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Epithelial Cells; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression; Humans; MAP Kinase Signaling System; Metribolone; Nitriles; Receptors, Androgen; Recombinant Proteins; Tosyl Compounds; Up-Regulation | 2012 |
Adaptive auto-regulation of androgen receptor provides a paradigm shifting rationale for bipolar androgen therapy (BAT) for castrate resistant human prostate cancer.
Topics: Androgen Antagonists; Androgens; Anilides; Animals; Cell Cycle; Cell Death; Cell Line, Tumor; DNA Replication; Flow Cytometry; Gene Expression Profiling; Humans; Immunohistochemistry; Male; Metribolone; Mice; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Tosyl Compounds; Xenograft Model Antitumor Assays | 2012 |
Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100.
Topics: Androgen Receptor Antagonists; Androgens; Androstenes; Androstenols; Anilides; Benzamides; Binding, Competitive; Cell Line, Tumor; Drug Interactions; Eplerenone; Humans; Male; Metribolone; Nitriles; Phenylthiohydantoin; Prednisolone; Prostatic Neoplasms; Receptors, Androgen; Spironolactone; Tosyl Compounds | 2012 |
A competitive inhibitor that reduces recruitment of androgen receptor to androgen-responsive genes.
Topics: Androgen Receptor Antagonists; Androgens; Anilides; Binding, Competitive; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Indoles; Luciferases; Male; Metribolone; Microscopy, Fluorescence; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Serine Endopeptidases; Small Molecule Libraries; Tosyl Compounds | 2012 |
Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site.
Topics: Androgen Receptor Antagonists; Anilides; Base Sequence; Binding Sites; Cell Line, Tumor; Chromatin; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Male; Metribolone; Nitriles; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Binding; Receptors, Androgen; Response Elements; Sp1 Transcription Factor; Testosterone Congeners; Tosyl Compounds; Transcriptional Activation; Up-Regulation; Vascular Endothelial Growth Factor A | 2013 |
Acetylcholine acts on androgen receptor to promote the migration and invasion but inhibit the apoptosis of human hepatocarcinoma.
Topics: Acetylcholine; Androgen Antagonists; Androgens; Anilides; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Mecamylamine; Metribolone; Neoplasm Invasiveness; Nitriles; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Androgen; Receptors, Cholinergic; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Tosyl Compounds; Transcription, Genetic; Up-Regulation | 2013 |
Androgen response element of the glycine N-methyltransferase gene is located in the coding region of its first exon.
Topics: Androgen Receptor Antagonists; Anilides; Base Sequence; Binding Sites; Cell Line, Tumor; Exons; Gene Expression Regulation, Neoplastic; Glycine N-Methyltransferase; Humans; Male; Metribolone; Nitriles; Open Reading Frames; Prostatic Neoplasms; Protein Binding; Receptors, Androgen; Response Elements; Sequence Analysis, DNA; Testosterone Congeners; Tosyl Compounds; Transcription, Genetic | 2013 |
HEXIM1 plays a critical role in the inhibition of the androgen receptor by anti-androgens.
Topics: Androgen Antagonists; Anilides; Cell Line, Tumor; Enhancer Elements, Genetic; Epithelial Cells; Gene Expression; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Male; Metribolone; Nitriles; Nuclear Proteins; Prostate; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Protein Transport; Receptors, Androgen; Repressor Proteins; RNA-Binding Proteins; Tosyl Compounds; Transcription Factors; Transcriptional Elongation Factors | 2014 |
Spheroid culture of LuCaP 147 as an authentic preclinical model of prostate cancer subtype with SPOP mutation and hypermutator phenotype.
Topics: Androgen Antagonists; Anilides; Animals; Cell Line, Tumor; Heterografts; Humans; Immunophenotyping; Male; Metribolone; Mice; Mutation; Nitriles; Nuclear Proteins; Phenotype; Prostatic Neoplasms; Repressor Proteins; Spheroids, Cellular; Tosyl Compounds; Ubiquitin-Protein Ligase Complexes | 2014 |