bicalutamide and finasteride

bicalutamide has been researched along with finasteride in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (21.43)18.2507
2000's15 (53.57)29.6817
2010's5 (17.86)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Brodie, AM; Chopra, P; Farquhar, R; Gediya, LK; Guo, Z; Handratta, VD; Kataria, R; Newman, D; Njar, VC; Qiu, Y; Vasaitis, TS1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barbolt, TA; Batzold, FH; Hollenbaugh, DM; Juniewicz, PE; Lemp, BM; McCarthy, M; Reel, JR; Shaw, C; Winneker, RC1
Barbolt, TA; Dube, JY; Egy, MA; Frenette, G; Juniewicz, PE; Tremblay, RR1
Akaza, H; Ideyama, Y; Imada, S; Koiso, K; Kudo, M; Shirai, T; Tsukamoto, S1
Johnson, H; McDermed, JE; Scholz, MC; Strum, SB; Tisman, G1
Akaza, H; Ideyama, Y; Onozawa, M; Shirai, T; Tsukamoto, S1
Andriole, GL; Bhayani, SB1
Bergh, A; Damber, JE; Lekås, E1
Bruchovsky, N; Crook, JM; Gleave, ME; Godwin, L; Goldenberg, SL; Hoffart, D; Klotz, LH; Sadar, M; Warkentin, M1
Leibowitz, RL; Tucker, SJ1
Amin, P; Chen, T; Dawson, N; Engstrom, C; Hussain, A; Naslund, M1
Tisman, G1
Bahnson, R; Bissonette, EA; Miller, NL; Theodorescu, D; Wilson, J1
Fukabori, Y; Honma, S; Kashiwagi, B; Ono, Y; Shibata, Y; Suzuki, K; Yamanaka, H1
Hellerstedt, B1
Ferrari, AC; McCarron, JP; Mencher, SK; Wang, LG1
Febbo, PG; George, DJ; Kantoff, PW; Kaplan, ID; Kaufman, DS; Leibowitz, SB; Manola, J; Oh, WK; Regan, MM; Smith, MR; Tay, MH1
Levinson, A; Lowe, FC; Nagler, EA1
Kaya, C; Ozyurek, M; Turkeri, LN1
Adomat, HH; Gleave, ME; Guns, ES; Hendy, SC; Locke, JA; Nelson, CC1
Bühler, P; Elsässer-Beile, U; Fischer, T; Gierschner, D; Schultze-Seemann, W; Wetterauer, U; Wolf, P1
Chhipa, RR; Ip, C; Wu, Y; Zhang, H1
Ahmed, HU; Arya, M; Day, E; Dobbs, C; Dudderidge, T; Emberton, M; Fiorentino, F; McCracken, S; Prevost, AT; Reddy, D; Shah, TT; Staffurth, J; Sydes, M; Winkler, M1
Pienta, KJ; Reyes, DK1

Reviews

4 review(s) available for bicalutamide and finasteride

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Hormonal manipulation for rising PSA after radical prostatectomy.
    Seminars in urologic oncology, 1999, Volume: 17, Issue:3

    Topics: Androgen Antagonists; Anilides; Drug Therapy, Combination; Enzyme Inhibitors; Finasteride; Flutamide; Humans; Male; Neoplasm Recurrence, Local; Nitriles; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Tosyl Compounds

1999
Hormonal therapy options for patients with a rising prostate-specific antigen level after primary treatment for prostate cancer.
    Urology, 2003, Dec-29, Volume: 62 Suppl 1

    Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Combined Modality Therapy; Diethylstilbestrol; Disease-Free Survival; Drug Administration Schedule; Enzyme Inhibitors; Finasteride; Gonadotropin-Releasing Hormone; Humans; Male; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Orchiectomy; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Salvage Therapy; Tosyl Compounds; Treatment Outcome

2003
Approach to management of clinically localized prostate cancer in patients with human immunodeficiency virus.
    Urology, 2005, Volume: 65, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Anilides; Antineoplastic Agents, Hormonal; Antiretroviral Therapy, Highly Active; Biomarkers, Tumor; Brachytherapy; Case Management; Combined Modality Therapy; Cryosurgery; Finasteride; Follow-Up Studies; HIV Infections; Humans; Leuprolide; Life Expectancy; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Proteins; Nitriles; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Radiotherapy, High-Energy; Retrospective Studies; Tosyl Compounds

2005

Trials

4 trial(s) available for bicalutamide and finasteride

ArticleYear
Intermittent androgen suppression for prostate cancer: Canadian Prospective Trial and related observations.
    Molecular urology, 2000,Fall, Volume: 4, Issue:3

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Cyclic AMP-Dependent Protein Kinases; Disease Progression; Enzyme Inhibitors; Finasteride; Humans; Male; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Quality of Life; Receptors, Androgen; Signal Transduction; Testosterone; Time Factors; Tosyl Compounds

2000
Treatment of localized prostate cancer with intermittent triple androgen blockade: preliminary results in 110 consecutive patients.
    The oncologist, 2001, Volume: 6, Issue:2

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Finasteride; Flutamide; Follow-Up Studies; Gonadotropin-Releasing Hormone; Goserelin; Humans; Leuprolide; Male; Middle Aged; Neoplasm Staging; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Tosyl Compounds; Treatment Outcome

2001
Docetaxel followed by hormone therapy after failure of definitive treatments for clinically localized/locally advanced prostate cancer: preliminary results.
    Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 15

    Topics: Adenocarcinoma; Aged; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Docetaxel; Finasteride; Goserelin; Humans; Leuprolide; Male; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Paclitaxel; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Salvage Therapy; Taxoids; Tosyl Compounds

2001
Comparative Healthcare Research Outcomes of Novel Surgery in prostate cancer (IP4-CHRONOS): A prospective, multi-centre therapeutic phase II parallel Randomised Control Trial.
    Contemporary clinical trials, 2020, Volume: 93

    Topics: Ablation Techniques; Androgen Antagonists; Anilides; Brachytherapy; Costs and Cost Analysis; Equivalence Trials as Topic; Finasteride; Humans; Male; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Nitriles; Progression-Free Survival; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Radiotherapy; Research Design; Tosyl Compounds; United Kingdom

2020

Other Studies

20 other study(ies) available for bicalutamide and finasteride

ArticleYear
Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.
    Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androstadienes; Animals; Antineoplastic Agents; Azoles; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Humans; Isoenzymes; Male; Mice; Mice, SCID; Mutation; Prostatic Neoplasms; Pyrazines; Radioligand Assay; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Tissue Distribution; Transcription, Genetic; Transcriptional Activation; Xenograft Model Antitumor Assays

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
The effect of the steroidal androgen receptor antagonist, Win 49,596, on the prostate and testis of beagle dogs.
    Endocrinology, 1990, Volume: 126, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androstenes; Anilides; Animals; Azasteroids; DNA; Dogs; Finasteride; Hypertrophy; Male; Nitriles; Orchiectomy; Organ Size; Pregnanes; Prostate; Prostatic Hyperplasia; Pyrazoles; Receptors, Androgen; Semen; Spermatogenesis; Testis; Testosterone; Tosyl Compounds; Ultrasonography

1990
Effects of androgen and antiandrogen treatment on canine prostatic arginine esterase.
    The Prostate, 1990, Volume: 17, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Androstane-3,17-diol; Androstenes; Anilides; Animals; Azasteroids; Capsules; Carboxylic Ester Hydrolases; Dogs; Dose-Response Relationship, Drug; Estradiol; Finasteride; Flutamide; Hyperplasia; Injections, Intramuscular; Male; Nitriles; Pregnanes; Prostate; Prostatectomy; Pyrazoles; Tosyl Compounds

1990
Chemoprevention of rat prostate carcinogenesis by use of finasteride or casodex.
    Journal of the National Cancer Institute, 1995, Jun-07, Volume: 87, Issue:11

    Topics: Androgen Antagonists; Anilides; Animals; Antineoplastic Agents; Finasteride; Male; Nitriles; Prostatic Neoplasms; Rats; Rats, Inbred F344; Tosyl Compounds

1995
Anaemia associated with androgen deprivation in patients with prostate cancer receiving combined hormone blockade.
    British journal of urology, 1997, Volume: 79, Issue:6

    Topics: Age Factors; Aged; Anemia; Anilides; Antineoplastic Combined Chemotherapy Protocols; Finasteride; Flutamide; Hemoglobins; Humans; Male; Nitriles; Prospective Studies; Prostatic Neoplasms; Testosterone; Time Factors; Tosyl Compounds

1997
A five-alpha reductase inhibitor or an antiandrogen prevents the progression of microscopic prostate carcinoma to macroscopic carcinoma in rats.
    Cancer, 1998, Feb-01, Volume: 82, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adenocarcinoma; Aminobiphenyl Compounds; Androgen Antagonists; Anilides; Animals; Carcinogens; Disease Progression; Enzyme Inhibitors; Finasteride; Male; Nitriles; Prostatic Neoplasms; Rats; Rats, Inbred F344; Testosterone; Tosyl Compounds

1998
Effects of finasteride and bicalutamide on prostatic blood flow in the rat.
    BJU international, 2000, Volume: 85, Issue:7

    Topics: Androgen Antagonists; Anilides; Animals; Enzyme Inhibitors; Finasteride; Male; Nitriles; Organ Size; Prostate; Prostatic Diseases; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tosyl Compounds

2000
Unusual anti-angiogenic effect of combined hormonal blockade.
    The Journal of urology, 2002, Volume: 168, Issue:4 Pt 1

    Topics: Aged; Angiogenesis Inhibitors; Anilides; Antineoplastic Agents, Hormonal; Capillaries; Chemotherapy, Adjuvant; Drug Therapy, Combination; Finasteride; Humans; Leuprolide; Male; Neoplasm Recurrence, Local; Nitriles; Prostatic Neoplasms; Skin; Telangiectasis; Tosyl Compounds; Treatment Outcome

2002
Impact of a novel neoadjuvant and adjuvant hormone-deprivation approach on quality of life, voiding function, and sexual function after prostate brachytherapy.
    Cancer, 2003, Mar-01, Volume: 97, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aged; Androgen Antagonists; Anilides; Brachytherapy; Chemotherapy, Adjuvant; Diarrhea; Enzyme Inhibitors; Finasteride; Flutamide; Humans; Logistic Models; Male; Nitriles; Penile Erection; Prostatic Neoplasms; Quality of Life; Tosyl Compounds; Treatment Outcome; Urinary Incontinence

2003
Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate.
    Urology, 2003, Volume: 62, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Androgen Antagonists; Anilides; Animals; Capillaries; Chlormadinone Acetate; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Hormone Antagonists; Male; Microcirculation; Nitriles; Prazosin; Prostate; Rats; Rats, Wistar; Sulfonamides; Tamsulosin; Testosterone; Tosyl Compounds

2003
The biological basis for the use of an anti-androgen and a 5-alpha-reductase inhibitor in the treatment of recurrent prostate cancer: Case report and review.
    Oncology reports, 2004, Volume: 11, Issue:6

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Aged; Androgen Antagonists; Anilides; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Drug Synergism; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Tumor Cells, Cultured

2004
Finasteride and bicalutamide as primary hormonal therapy in patients with advanced adenocarcinoma of the prostate.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:6

    Topics: Adenocarcinoma; Aged; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Erectile Dysfunction; Finasteride; Humans; Male; Middle Aged; Neoplasm Staging; Nitriles; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Tosyl Compounds

2004
Comparison of microvessel densities in rat prostate tissues treated with finasteride, bicalutamide and surgical castration: a preliminary study.
    International journal of urology : official journal of the Japanese Urological Association, 2005, Volume: 12, Issue:2

    Topics: Androgen Antagonists; Anilides; Animals; Castration; Dissection; Enzyme Inhibitors; Finasteride; Immunohistochemistry; Male; Neovascularization, Pathologic; Nitriles; Prostate; Rats; Rats, Sprague-Dawley; Tosyl Compounds

2005
Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts.
    The Journal of steroid biochemistry and molecular biology, 2009, Volume: 115, Issue:3-5

    Topics: Androgen Antagonists; Androgens; Anilides; Animals; Castration; Cell Line, Tumor; Cinnamates; Disease Progression; Drug Combinations; Enzyme Inhibitors; Finasteride; Gene Expression Regulation, Neoplastic; Humans; Ketoconazole; Male; Mice; Mice, Nude; Mifepristone; Molecular Structure; Neoplasm Transplantation; Nitriles; Progesterone; Prostatic Neoplasms; Steroids; Tosyl Compounds; Transplantation, Heterologous

2009
Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors.
    Urologia internationalis, 2010, Volume: 84, Issue:2

    Topics: Anilides; Antineoplastic Agents; Azasteroids; Cell Differentiation; Cell Line, Tumor; Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Nitriles; Oligonucleotide Array Sequence Analysis; Prostate; Prostatic Neoplasms; Tosyl Compounds

2010
The antiandrogenic effect of finasteride against a mutant androgen receptor.
    Cancer biology & therapy, 2011, May-15, Volume: 11, Issue:10

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Finasteride; Gene Expression Regulation; Gene Knockdown Techniques; Homeodomain Proteins; Humans; Mutation; Nitriles; Receptors, Androgen; Tosyl Compounds

2011
Peripheral androgen blockade in men with castrate-sensitive biochemical recurrent prostate cancer.
    Medical oncology (Northwood, London, England), 2021, Jun-05, Volume: 38, Issue:7

    Topics: Aged; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Finasteride; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Prostatic Neoplasms, Castration-Resistant; Tosyl Compounds

2021