bicalutamide and dihydrotestosterone

bicalutamide has been researched along with dihydrotestosterone in 88 studies

Research

Studies (88)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	11 (12.50)	18.2507
2000's	39 (44.32)	29.6817
2010's	32 (36.36)	24.3611
2020's	6 (6.82)	2.80

Authors

Authors	Studies
Ackerman, JH; Bell, MR; Christiansen, RG; D'Ambra, TE; Herrmann, JL; Kullnig, RK; Mallamo, JP; Opalka, CJ; Snyder, BW; Winneker, RC	1
Edwards, JP; Farmer, LJ; Jones, TK; Marschke, KB; Pooley, CL; West, SJ	1
Caferro, TR; Edwards, JP; Goldman, ME; Hamann, LG; Higuchi, RI; Jones, TK; Marschke, KB; Pooley, CL; Winn, DT; Zhi, L	1
Higuchi, RI; Jones, TK; Marschke, KB; Negro-Vilar, A; Pio, BA; Tegley, CM; van Oeveren, A; Wu, M; Zhi, L	1
Chang, WY; Lau, TL; Long, YO; López, FJ; Marschke, KB; Martinborough, E; Negro-Vilar, A; Oeveren, Av; Rix, PJ; Shen, Y; Vajda, EG; Viveros, OH; Zhi, L	1
Caferro, TR; Chang, WY; Cummings, ML; Higuchi, RI; Karanewsky, DS; Lau, TL; Long, YO; López, FJ; Marschke, KB; Martinborough, EA; Wu, M; Zhi, L	1
Marschke, KB; Shen, Y; van Oeveren, A; Zhao, S; Zhi, L	1
Amano, S; Furuya, K; Inoguchi, K; Miyakawa, M; Nagata, N; Yamamoto, N	1
Bohl, CE; Dalton, JT; Duke, CB; Jones, A; Miller, DD	1
Amano, S; Furuya, K; Inoguchi, K; Miyakawa, M; Nagata, N; Nejishima, H; Yamamoto, N	1
Furuya, S; Hamamura, K; Hara, T; Hitaka, T; Ito, M; Kanzaki, N; Kusaka, M; Matsunaga, N; Miyazaki, J; Santou, T; Tasaka, A; Yamada, M; Yamamoto, S; Yamaoka, M	1
Aikawa, K; Baba, A; Hara, T; Hasuoka, A; Ito, M; Kaku, T; Kanzaki, N; Kobayashi, H; Yamamoto, S; Yamaoka, M	1
Bian, J; Chen, R; Li, M; Li, Z; Tang, J; Tian, Y; Xie, Y; Xu, X; Zhang, Y; Zhang, Z	1
Wang, S; Xiang, W	1
Eri, LM; Haug, E; Tveter, KJ	1
Esquenet, M; Goossens, K; Heyns, W; Swinnen, JV; Verhoeven, G	1
Jimenez, J; Luizzi, MF; Sonnenschein, C; Soto, AM; Szelei, J	1
Feldman, D; Ly, LH; Peehl, DM; Zhao, XY	1
Dalton, JT; Kirkovsky, L; Miller, DD; Mukherjee, A; Zhu, Z	1
Budman, DR; Kreis, W; Liu, XM; Wang, LG	1
Hackenberg, R; Loos, S; Schulz, KD	1
Calandra, RS; Cónsole, GG; Gómez Dumm, CL; Riccillo, FL; Rulli, SB	1
di Salle, E; Giudici, D; Panzeri, A; Zaccheo, T	1
Ahn, SC; Chatterjee, B; Lavrovsky, Y; Roy, AK; Song, CS; Tyagi, RK	1
Fujimoto, N; Harada, S; Keller, ET; Koshida, K; Matsumoto, T; Mizokami, A; Namiki, M	1
Calandra, RS; Cónsole, GM; Gómez Dumm, CL; Jurado, SB; Rulli, SB	1
Brive, L; Ely, KR; Feldman, D; Krishnan, AV; Peehl, DM; Swami, S; Zhao, XY	1
Furutani, T; Hashimoto, T; Kato, S; Koutoku, H; Kudoh, M; Shikama, H; Shimizu, Y; Tanimoto, K; Watanabe, T	1
Bjeldanes, LF; Firestone, GL; Le, HT; Schaldach, CM	1
Cox, ME; Mulholland, DJ; Nelson, CC; Read, JT; Rennie, PS	1
Artaza, JN; Bhasin, S; Gonzalez-Cadavid, NF; Singh, R; Taylor, WE	1
Burnstein, KL; Hayakawa, K; Kizu, R; Klinge, CM; Mizokami, A; Okamura, K; Toriba, A	1
Chen, F; Iwamoto, Y; Langenstroer, P; See, W; Zhang, G	1
Fukabori, Y; Honma, S; Kashiwagi, B; Ono, Y; Shibata, Y; Suzuki, K; Yamanaka, H	1
Tai, HH; Tong, M	1
Andò, S; Briand, PA; Carpino, A; Fasanella, G; Maggiolini, M; Pezzi, V; Picard, D; Rago, V; Recchia, AG; Vivacqua, A	1
Bai, C; Chen, F; Freedman, L; Gambone, C; Harada, S; Kasparcova, V; Knecht, K; Leu, C; Reszka, A; Rutledge, SJ; Scafonas, A; Schmidt, A; Vogel, R; Zhang, H	1
Cheskis, B; Mancini, MA; Marcelli, M; McPhaul, MJ; Nan, B; Sun, S; Unni, E	1
Dunkel, L; Mäkinen, S; Matikainen, T; Otala, M; Pentikäinen, V; Sjöberg, J; Tuuri, T	1
Baltogiannis, D; Charalabopoulos, K; Giannakopoulos, X; Sofikitis, N	1
Lou, YR; Nazarova, N; Talonpoika, R; Tuohimaa, P	1
Angelucci, A; Bologna, M; Festuccia, C; Gravina, GL; Millimaggi, D; Muzi, P; Vicentini, C	1
Baniahmad, A; Klug, J; Mirwald, A; Papaioannou, M; Xiao, F	1
Catapano, AL; Norata, GD; Poletti, A; Seccomandi, PM; Tibolla, G	1
Arnold, JT; Blackman, MR; Le, H; McFann, KK	1
Luo, W; Wiltbank, MC	1
Chang, CY; Elbi, C; Hager, GL; Hendarwanto, A; Klokk, TI; Kurys, P; Nagaich, AK; Saatcioglu, F; Slagsvold, T	1
De Rosier, T; Eliason, HC; Ervin, KM; Gowda, K; Kupcho, KR; Marks, BD; Ozers, MS; Qadir, N; Riddle, SM; Shekhani, MS	1
Fuse, H; Hiyama, T; Ito, T; Kato, S; Kimura, K; Korenaga, S; Sakari, M	1
Arnold, RS; Chung, LW; Fujisawa, M; Gotoh, A; Kubo, H; Shigemura, K; Sung, SY; Zhau, HE	1
Banham, AH; Boddy, J; Fox, SB; Han, C; Harris, AL; Launchbury, R; Malone, PR; Turley, H	1
Dervan, PB; Nickols, NG	1
Bologna, M; Festuccia, C; Gravina, GL; Muzi, P; Pomante, R; Ricevuto, E; Ventura, L; Vicentini, C	1
Dong, Z; Lu, S; Wang, A	1
Arasheben, A; Barski, A; Coetzee, GA; Cogan, JP; Frenkel, B; Jariwala, U; Jia, L; Neilson, JJ; Pregizer, S; Prescott, J; Shen, HC	1
Banham, AH; Boddy, JL; Campo, L; Fox, SB; Harris, AL; Jones, C; Kanga, S; Launchbury, R; Malone, PR; Shaida, N; Turley, H	1
Bagalà, C; Barone, C; Bianchetti, S; Cassano, A; Fabiano, A; Landriscina, M; Piscazzi, A; Quirino, M; Schinzari, G; Sica, G	1
Dubbink, HJ; Hersmus, R; Jenster, G; Lusher, SJ; Molier, M; Trapman, J; van de Wijngaart, DJ	1
Aoki, Y; Ishikura, N; Kawata, H; Nishimoto, A; Tsunenari, T; Watanabe, M	1
Craig, M; McGregor, N; Patel, L; Pienta, KJ; Wang, S; Weidner, S	1
Bolzoni, E; Jenkins, SC; Joseph, JD; Liu, Y; McDonnell, DP; Merry, DE; Montie, HL; Orr, CR; Wilson, EM	1
Cai, J; Hong, Y; Imperato-McGinley, J; Tan, C; Weng, C; Zhu, YS	1
Chhipa, RR; Ip, C; Wu, Y; Zhang, H	1
Hagler, AT; Osguthorpe, DJ	1
deVere White, RW; Shi, D; Shi, XB; Xue, L	1
Bailey, ST; Brown, M; Chen, Y; Imai, Y; Lim, E; Liu, XS; Ni, M; Rimm, DL; Wimberly, H	1
Caradec, J; Chimingqi, M; de la Taille, A; Giton, F; Kouyoumdjian, JC; Loric, S; Moutereau, S; Sirab, N; Terry, S; Vacherot, F	1
Argellati, F; Boccardo, F; Mangerini, R; Nuzzo, PV; Ricci, F; Rubagotti, A	1
Ha, YS; Jung, YS; Kim, IY; Kim, JH; Kim, WJ; Lee, GT	1
Bianco-Miotto, T; Birrell, SN; Butler, LM; Hickey, TE; Jankovic-Karasoulos, T; Moore, NL; Ochnik, AM; Ryan, NK; Thomas, MR; Tilley, WD	1
Balk, S; Ellis, W; Gulati, R; Hunter Merrill, R; Kantoff, P; Lange, P; Lin, DW; Marck, B; Matsumoto, AM; Montgomery, B; Mostaghel, EA; Nelson, PS; Penning, T; Tamae, D; Taplin, ME; True, LD; Vessella, R	1
Hayashi, H; Igawa, T; Izumida, M; Kakoki, K; Kamiyama, H; Kubo, Y; Matsuyama, T; Sakai, H; Yamamoto, N; Yashima, Y	1
Goodman, MM; Kawai, K; Kobayashi, M; Nakanishi, T; Oka, S; Okudaira, H; Ono, M; Schuster, DM; Shirakami, Y; Tamai, I	1
Chang, YL; Chiu, WJ; Hsu, YK; Huang, CM; Luo, FJ; Weng, CF; Wu, TF; Yuan, TC	1
Gooderham, NJ; Koufaris, C; Powell, C; Segal, CV	1
Chaytor, L; Gaughan, L; Grey, J; Jones, D; Nakjang, S; Robson, CN; Wade, M	1
Inouye, Y; Kanno, Y; Nemoto, K; Yamashita, N; Yanai, K; Zhao, S	1
Guan, X; Li, Y; Song, W; Xu, Y; Yang, F; Yin, Y; Zhang, W; Zhu, A	1
Bogner, J; Hickson, I; Romer, T; Yurlova, L; Zolghadr, K	1
Hara, N; Ishizaki, F; Nishiyama, T; Takeda, K; Tasaki, M; Tomita, Y	1
El-Shishtawy, KA; Ide, H; Kashiwagi, E; Kawahara, T; Li, Y; Miyamoto, H; Reis, LO; Zheng, Y	1
Cunningham, RL; Duong, P; Tenkorang, MAA	1
Gu, Y; Li, H; Li, J; Song, W; Wang, J; Wang, W; Xia, Q; Xu, W; Yang, Y; Zhang, X; Zou, K	1
Azhagiya Singam, ER; Durkin, KA; La Merrill, MA; Smith, MT; Tachachartvanich, P	1
Boers, J; Boersma, HH; de Vries, EFJ; Dorbritz, C; Glaudemans, AWJM; Hospers, GAP; Rikhof, B; Schröder, CP; Venema, CM	1
Brás, LA; Cardoso, HJ; Carvalho, TMA; Figueira, MI; Madureira, PA; Oliveira, PJ; Sardão, VA; Socorro, S; Vaz, CV	1
Chen, Y; Du, L; Fu, D; Guo, Y; He, Y; Hu, Z; Huang, J; Li, K; Miao, Y; Qu, Q; Sun, Y	1
Gim, HJ; Houk, KN; Jung, ME; Park, J	1

Reviews

3 review(s) available for bicalutamide and dihydrotestosterone

Article	Year
Overview of the development of selective androgen receptor modulators (SARMs) as pharmacological treatment for osteoporosis (1998-2021). European journal of medicinal chemistry, 2022, Feb-15, Volume: 230 Topics: Androgen Antagonists; Androgens; Humans; Osteoporosis; Receptors, Androgen; Structure-Activity Relationship	2022
Therapeutic Strategies to Target the Androgen Receptor. Journal of medicinal chemistry, 2022, 07-14, Volume: 65, Issue:13 Topics: Androgen Antagonists; Androgen Receptor Antagonists; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen	2022
Monotherapy in advanced prostate cancer: an overview. Experimental oncology, 2004, Volume: 26, Issue:3 Topics: Adenocarcinoma; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Cyproterone Acetate; Dihydrotestosterone; Estrogens; Flutamide; Gonadotropin-Releasing Hormone; Humans; Imidazolidines; Male; Nitriles; Orchiectomy; Palliative Care; Progesterone Congeners; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Testosterone; Tosyl Compounds	2004

Trials

3 trial(s) available for bicalutamide and dihydrotestosterone

Article	Year
Effects on the endocrine system of long-term treatment with the non-steroidal anti-androgen Casodex in patients with benign prostatic hyperplasia. British journal of urology, 1995, Volume: 75, Issue:3 Topics: Aged; Androgen Antagonists; Androstenedione; Anilides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Double-Blind Method; Estradiol; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Nitriles; Prolactin; Prostatic Hyperplasia; Testosterone; Tosyl Compounds	1995
Targeted androgen pathway suppression in localized prostate cancer: a pilot study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jan-20, Volume: 32, Issue:3 Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Androgen Antagonists; Androgen Receptor Antagonists; Androsterone; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Azasteroids; Biomarkers, Tumor; Chemotherapy, Adjuvant; Dihydrotestosterone; Dutasteride; Goserelin; Humans; Ketoconazole; Male; Middle Aged; Molecular Targeted Therapy; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Pilot Projects; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Steroid 17-alpha-Hydroxylase; Testosterone; Tosyl Compounds; Treatment Outcome	2014
Serial [ European journal of cancer (Oxford, England : 1990), 2021, Volume: 144 Topics: Aged; Androgen Antagonists; Anilides; Breast Neoplasms; Dihydrotestosterone; Female; Fluorine Radioisotopes; Follow-Up Studies; Humans; Neoplasm Metastasis; Nitriles; Positron-Emission Tomography; Prognosis; Prospective Studies; Radiopharmaceuticals; Receptors, Androgen; Tosyl Compounds	2021

Other Studies

82 other study(ies) available for bicalutamide and dihydrotestosterone

Article	Year
Antiandrogenic steroidal sulfonylpyrazoles. Journal of medicinal chemistry, 1990, Volume: 33, Issue:8 Topics: Androgen Antagonists; Animals; Male; Molecular Structure; Orchiectomy; Organ Size; Pregnanes; Prostate; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Androgen; Structure-Activity Relationship; Testosterone; X-Ray Diffraction	1990
New nonsteroidal androgen receptor modulators based on 4-(trifluoromethyl)-2(1H)-pyrrolidino[3,2-g] quinolinone. Bioorganic & medicinal chemistry letters, 1998, Apr-07, Volume: 8, Issue:7 Topics: Androgen Antagonists; Anilides; Animals; Cell Line; Drug Design; Flutamide; Gene Expression Regulation; Humans; Molecular Structure; Nitriles; Pyrrolidines; Quinolines; Quinolones; Receptors, Androgen; Recombinant Proteins; Structure-Activity Relationship; Tosyl Compounds; Transcription, Genetic; Transfection	1998
Nonsteroidal androgen receptor agonists based on 4-(trifluoromethyl)-2H-pyrano[3,2-g]quinolin-2-one. Bioorganic & medicinal chemistry letters, 1999, Apr-05, Volume: 9, Issue:7 Topics: Androgens; Animals; Benzopyrans; Cell Line; COS Cells; Humans; Quinolones; Receptors, Androgen; Structure-Activity Relationship; Transcription, Genetic; Transfection	1999
Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones. Bioorganic & medicinal chemistry letters, 2007, Mar-15, Volume: 17, Issue:6 Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Animals; Cell Line; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nitriles; Quinolines; Receptors, Androgen; Structure-Activity Relationship; Tosyl Compounds; Transfection	2007
Substituted 6-(1-pyrrolidine)quinolin-2(1H)-ones as novel selective androgen receptor modulators. Journal of medicinal chemistry, 2007, Oct-18, Volume: 50, Issue:21 Topics: Administration, Oral; Anabolic Agents; Androgen Receptor Antagonists; Androgens; Animals; Biological Availability; Bone Density Conservation Agents; Female; Humans; Hypogonadism; Male; Muscle, Skeletal; Organ Size; Osteoporosis, Postmenopausal; Prostate; Pyrrolidines; Quinolines; Quinolones; Rats; Stereoisomerism; Structure-Activity Relationship	2007
Selective androgen receptor modulators based on a series of 7H-[1,4]oxazino[3,2-g]quinolin-7-ones with improved in vivo activity. Bioorganic & medicinal chemistry letters, 2008, May-01, Volume: 18, Issue:9 Topics: Administration, Oral; Anabolic Agents; Androgen Receptor Antagonists; Androgens; Animals; Male; Models, Chemical; Orchiectomy; Organ Size; Oxazines; Prostate; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Structure-Activity Relationship; Testosterone	2008
Discovery of a novel series of nonsteroidal androgen receptor modulators: 5- or 6-oxachrysen-2-ones. Bioorganic & medicinal chemistry letters, 2008, Jun-01, Volume: 18, Issue:11 Topics: Androgens; Anilides; Combinatorial Chemistry Techniques; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Nitriles; Quinolones; Structure-Activity Relationship; Tosyl Compounds	2008
Design and synthesis of tricyclic tetrahydroquinolines as a new series of nonsteroidal selective androgen receptor modulators (SARMs). Bioorganic & medicinal chemistry letters, 2011, Mar-15, Volume: 21, Issue:6 Topics: Drug Design; Models, Molecular; Quinolines; Receptors, Androgen	2011
Unexpected binding orientation of bulky-B-ring anti-androgens and implications for future drug targets. Journal of medicinal chemistry, 2011, Jun-09, Volume: 54, Issue:11 Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Crystallography, X-Ray; Drug Design; Drug Resistance, Neoplasm; Humans; Male; Molecular Structure; Molecular Targeted Therapy; Prostatic Neoplasms; Protein Binding; Receptors, Androgen; Structure-Activity Relationship	2011
Tetrahydroquinolines as a novel series of nonsteroidal selective androgen receptor modulators: structural requirements for better physicochemical and biological properties. Bioorganic & medicinal chemistry letters, 2011, Nov-01, Volume: 21, Issue:21 Topics: Animals; Bone Density; Female; Osteoporosis; Ovariectomy; Quinolines; Rats; Receptors, Androgen	2011
Design, synthesis, and biological evaluation of 4-phenylpyrrole derivatives as novel androgen receptor antagonists. Bioorganic & medicinal chemistry, 2012, Jan-01, Volume: 20, Issue:1 Topics: Amino Acid Substitution; Androgen Receptor Antagonists; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Resistance, Neoplasm; Humans; Male; Mice; Mice, Inbred ICR; Mice, Nude; Mutation; Prostatic Neoplasms; Pyrroles; Receptors, Androgen; Transplantation, Heterologous	2012
Design, synthesis, and biological evaluation of 3-aryl-3-hydroxy-1-phenylpyrrolidine derivatives as novel androgen receptor antagonists. Bioorganic & medicinal chemistry, 2013, Jan-01, Volume: 21, Issue:1 Topics: Androgen Receptor Antagonists; Animals; Antineoplastic Agents; Castration; Cell Line, Tumor; Drug Design; Humans; Male; Mice; Models, Molecular; Prostate; Prostatic Neoplasms; Pyrrolidines; Receptors, Androgen; Xenograft Model Antitumor Assays	2013
Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP. Cancer research, 1997, Mar-15, Volume: 57, Issue:6 Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme Induction; Fatty Acid Synthases; Gene Expression Regulation, Neoplastic; Humans; Lipids; Male; Metribolone; Nandrolone; Neoplasm Proteins; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Testosterone Congeners; Tosyl Compounds; Tumor Cells, Cultured	1997
Androgen-induced inhibition of proliferation in human breast cancer MCF7 cells transfected with androgen receptor. Endocrinology, 1997, Volume: 138, Issue:4 Topics: Androgen Antagonists; Androgens; Anilides; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Flutamide; Humans; In Vitro Techniques; Metribolone; Nandrolone; Nitriles; Receptors, Androgen; Testosterone; Testosterone Congeners; Tosyl Compounds; Transfection; Tumor Cells, Cultured	1997
1alpha,25-dihydroxyvitamin D3 actions in LNCaP human prostate cancer cells are androgen-dependent. Endocrinology, 1997, Volume: 138, Issue:8 Topics: Analysis of Variance; Androgen Antagonists; Androgens; Anilides; Blotting, Northern; Blotting, Western; Calcitriol; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Tritium; Tumor Cells, Cultured; Up-Regulation	1997
Discovery of nonsteroidal androgens. Biochemical and biophysical research communications, 1998, Mar-06, Volume: 244, Issue:1 Topics: Androgens; Anilides; Animals; Binding, Competitive; Dihydrotestosterone; Kinetics; Ligands; Male; Nandrolone; Nitriles; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Testosterone Congeners; Tosyl Compounds	1998
Phosphorylation/dephosphorylation of androgen receptor as a determinant of androgen agonistic or antagonistic activity. Biochemical and biophysical research communications, 1999, May-27, Volume: 259, Issue:1 Topics: Androgen Antagonists; Androgens; Anilides; Animals; Base Sequence; Dihydrotestosterone; Estradiol; Estramustine; Flutamide; Humans; Ligands; Male; Molecular Sequence Data; Nitriles; Phosphorylation; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured	1999
Regulation of GCDFP-15 expression in human mammary cancer cells. International journal of molecular medicine, 1999, Volume: 4, Issue:2 Topics: Androgen Antagonists; Anilides; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carrier Proteins; Cell Division; Dihydrotestosterone; Flutamide; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Membrane Transport Proteins; Nitriles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured	1999
Effects of androgens and antiandrogens on the quantitative immunohistochemistry of gonadotrope cells in prepubertal male rats. Neuroendocrinology, 1999, Volume: 70, Issue:4 Topics: Androgen Antagonists; Anilides; Animals; Dihydrotestosterone; Flutamide; Follicle Stimulating Hormone; Immunohistochemistry; Luteinizing Hormone; Male; Nitriles; Orchiectomy; Pituitary Gland; Rats; Rats, Sprague-Dawley; Sexual Maturation; Tosyl Compounds	1999
Combined treatment of Dunning R3327 rat prostatic tumor with the 5alpha-reductase inhibitor PNU 157706 and the antiandrogen bicalutamide. Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:1 Topics: Androgen Antagonists; Androstenes; Anilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Enzyme Inhibitors; Male; Nitriles; Organ Size; Oxidoreductases; Prostatic Neoplasms; Rats; Testosterone; Tosyl Compounds	2000
Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cells. Molecular endocrinology (Baltimore, Md.), 2000, Volume: 14, Issue:8 Topics: Androgen Antagonists; Anilides; Animals; Biological Transport, Active; Cell Compartmentation; Cell Line; Cell Nucleus; Cyproterone; Cytoplasm; Dihydrotestosterone; Estradiol; Fatty Acids, Unsaturated; Green Fluorescent Proteins; Humans; Kinetics; Ligands; Luminescent Proteins; Nitriles; Progesterone; Rats; Receptors, Androgen; Recombinant Proteins; Tosyl Compounds; Transcriptional Activation	2000
Long-term exposure of tumor necrosis factor alpha causes hypersensitivity to androgen and anti-androgen withdrawal phenomenon in LNCaP prostate cancer cells. The Prostate, 2001, Mar-01, Volume: 46, Issue:4 Topics: Androgen Antagonists; Anilides; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Dihydrotestosterone; Humans; Luciferases; Male; Nitriles; Prostatic Neoplasms; Time Factors; Tosyl Compounds; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	2001
Ultrastructural and quantitative immunohistochemical changes induced by nonsteroid antiandrogens on pituitary gonadotroph population of prepubertal male rats. Cells, tissues, organs, 2001, Volume: 169, Issue:1 Topics: Androgen Antagonists; Anilides; Animals; Dihydrotestosterone; Flutamide; Follicle Stimulating Hormone; Hormone Replacement Therapy; Immunohistochemistry; Luteinizing Hormone; Male; Microscopy, Electron; Nitriles; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Secretory Vesicles; Sexual Maturation; Tosyl Compounds	2001
A glucocorticoid-responsive mutant androgen receptor exhibits unique ligand specificity: therapeutic implications for androgen-independent prostate cancer. Endocrinology, 2002, Volume: 143, Issue:5 Topics: Androgen Antagonists; Androgens; Anilides; Binding, Competitive; Cell Line; Dihydrotestosterone; Fludrocortisone; Genes, Reporter; Glucocorticoids; Humans; Hydrocortisone; Kinetics; Ligands; Male; Mifepristone; Models, Molecular; Mutation; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Radioligand Assay; Receptors, Androgen; Tosyl Compounds; Triamcinolone	2002
Stabilization of androgen receptor protein is induced by agonist, not by antagonists. Biochemical and biophysical research communications, 2002, Jun-21, Volume: 294, Issue:4 Topics: Androgen Receptor Antagonists; Androgens; Anilides; Animals; Blotting, Northern; Blotting, Western; CHO Cells; Cricetinae; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Humans; Ligands; Luciferases; Nitriles; Plasmids; Receptors, Androgen; RNA Processing, Post-Transcriptional; Time Factors; Tosyl Compounds; Transcriptional Activation; Transfection; Tumor Cells, Cultured	2002
Plant-derived 3,3'-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells. The Journal of biological chemistry, 2003, Jun-06, Volume: 278, Issue:23 Topics: Adenocarcinoma; Androgen Antagonists; Anilides; Animals; Anticarcinogenic Agents; Binding, Competitive; Cell Division; Cell Nucleus; Cytoplasm; Dihydrotestosterone; DNA; Gene Expression Regulation, Neoplastic; Indoles; Male; Metribolone; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Signal Transduction; Testosterone Congeners; Tosyl Compounds; Transcription, Genetic; Tumor Cells, Cultured; Vegetables	2003
Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis. Oncogene, 2003, Aug-28, Volume: 22, Issue:36 Topics: Anilides; beta Catenin; Binding, Competitive; Cell Nucleus; Colonic Neoplasms; Cytoskeletal Proteins; Dihydrotestosterone; DNA-Directed RNA Polymerases; Humans; Male; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; TCF Transcription Factors; Tosyl Compounds; Trans-Activators; Transcription Factor 7-Like 2 Protein; Transcription Factors; Tumor Cells, Cultured	2003
Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Endocrinology, 2003, Volume: 144, Issue:11 Topics: Adipocytes; Androgen Antagonists; Androgens; Anilides; Animals; Cell Differentiation; Cell Division; Cell Line; Dihydrotestosterone; Mice; Mice, Inbred C3H; Muscle, Skeletal; Nitriles; Pluripotent Stem Cells; Receptors, Androgen; Testosterone; Tosyl Compounds	2003
Antiandrogenic activities of diesel exhaust particle extracts in PC3/AR human prostate carcinoma cells. Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 76, Issue:2 Topics: Adenocarcinoma; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Benzoflavones; beta-Galactosidase; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Luciferases; Male; Nitriles; Polycyclic Aromatic Hydrocarbons; Proadifen; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Receptors, Aryl Hydrocarbon; Saccharomyces cerevisiae; Tosyl Compounds; Vehicle Emissions	2003
Androgen dependent regulation of bacillus Calmette-Guerin induced interleukin-6 expression in human transitional carcinoma cell lines. The Journal of urology, 2003, Volume: 170, Issue:5 Topics: Androgen Antagonists; Anilides; Autocrine Communication; BCG Vaccine; Carcinoma, Transitional Cell; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Genes, Reporter; Humans; Neoplasms, Hormone-Dependent; NF-kappa B; Nitriles; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Vaccines, Attenuated	2003
Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate. Urology, 2003, Volume: 62, Issue:5 Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Androgen Antagonists; Anilides; Animals; Capillaries; Chlormadinone Acetate; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Hormone Antagonists; Male; Microcirculation; Nitriles; Prazosin; Prostate; Rats; Rats, Wistar; Sulfonamides; Tamsulosin; Testosterone; Tosyl Compounds	2003
Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells. Endocrinology, 2004, Volume: 145, Issue:5 Topics: Androgen Antagonists; Anilides; Blotting, Western; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dihydrotestosterone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Interleukin-6; Isoquinolines; Kinetics; Male; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; STAT3 Transcription Factor; Sulfonamides; Tosyl Compounds; Trans-Activators; Tumor Cells, Cultured	2004
Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells. Journal of molecular endocrinology, 2004, Volume: 32, Issue:3 Topics: Androgen Antagonists; Androgens; Anilides; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Estrogen Receptor beta; Fulvestrant; Genes, Reporter; Humans; Male; Nitriles; Oligonucleotides, Antisense; Prostatic Neoplasms; Receptors, Androgen; Response Elements; Tosyl Compounds	2004
Partial agonist/antagonist properties of androstenedione and 4-androsten-3beta,17beta-diol. The Journal of steroid biochemistry and molecular biology, 2004, Volume: 91, Issue:4-5 Topics: Adaptor Proteins, Signal Transducing; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Androstenediol; Androstenedione; Anilides; Animals; Breast Neoplasms; Carrier Proteins; Cell Division; Chlorocebus aethiops; COS Cells; Cyproterone Acetate; Dihydrotestosterone; Humans; Ligands; Macaca mulatta; Male; Mammary Tumor Virus, Mouse; Mice; Nerve Tissue Proteins; Nitriles; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, AMPA; Receptors, Androgen; Tosyl Compounds; Transcription, Genetic; Tumor Cells, Cultured	2004
Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence. Cancer research, 2004, Oct-01, Volume: 64, Issue:19 Topics: Activating Transcription Factor 1; Anilides; Animals; Cell Line, Tumor; Co-Repressor Proteins; Dihydrotestosterone; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasms, Hormone-Dependent; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; src-Family Kinases; Tosyl Compounds; Trans-Activators; Transcription Factors	2004
Effects of testosterone, dihydrotestosterone, and 17beta-estradiol on human ovarian tissue survival in culture. Fertility and sterility, 2004, Volume: 82 Suppl 3 Topics: Adult; Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Apoptosis; Cell Survival; Culture Techniques; Dihydrotestosterone; Estradiol; Female; Granulosa Cells; Humans; Nitriles; Ovary; Prospective Studies; Receptors, Androgen; Testosterone; Tissue Survival; Tosyl Compounds	2004
5alpha-dihydrotestosterone inhibits 1alpha,25-dihydroxyvitamin D3-induced expression of CYP24 in human prostate cancer cells. The Prostate, 2005, May-15, Volume: 63, Issue:3 Topics: Androgen Receptor Antagonists; Androgens; Anilides; Calcitriol; Cycloheximide; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Drug Interactions; Flutamide; Gene Expression Regulation, Enzymologic; Humans; Male; Nitriles; Prostatic Neoplasms; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Steroid Hydroxylases; Tosyl Compounds; Tumor Cells, Cultured; Vitamin D3 24-Hydroxylase	2005
Additive antitumor effects of the epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib (Iressa), and the nonsteroidal antiandrogen, bicalutamide (Casodex), in prostate cancer cells in vitro. International journal of cancer, 2005, Jul-01, Volume: 115, Issue:4 Topics: Androgen Antagonists; Anilides; Animals; Antineoplastic Agents; Cell Division; Cell Line, Tumor; Dihydrotestosterone; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Humans; Male; Nitriles; Prostatic Neoplasms; Quinazolines; Tosyl Compounds; Transplantation, Heterologous	2005
Secretoglobin 2A1 is under selective androgen control mediated by a peculiar binding site for Sp family transcription factors. Molecular endocrinology (Baltimore, Md.), 2005, Volume: 19, Issue:12 Topics: Androgen Antagonists; Androgens; Anilides; Base Sequence; Binding Sites; Carrier Proteins; Cells, Cultured; Chromatin; Dihydrotestosterone; Gene Expression Regulation; Humans; Immunoprecipitation; Male; Mammaglobin B; Molecular Sequence Data; Mutation; Myelin Proteins; NFI Transcription Factors; Nitriles; Promoter Regions, Genetic; Prostate; Protein Structure, Tertiary; Proteolipids; Repetitive Sequences, Nucleic Acid; Response Elements; Secretoglobins; Sp Transcription Factors; Tosyl Compounds; Uteroglobin	2005
Dihydrotestosterone decreases tumor necrosis factor-alpha and lipopolysaccharide-induced inflammatory response in human endothelial cells. The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:2 Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Cell Line, Tumor; Cyclooxygenase 2; Dihydrotestosterone; Drug Interactions; E-Selectin; Endothelial Cells; Humans; Immunoblotting; Inflammation; Intercellular Adhesion Molecule-1; Lipopolysaccharides; NF-kappa B; Nitriles; Platelet Endothelial Cell Adhesion Molecule-1; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2006
DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells. American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:5 Topics: Androgen Antagonists; Anilides; Cell Proliferation; Cells, Cultured; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Flutamide; Gene Expression; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 5; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Middle Aged; Nitriles; Prostate; Receptor, IGF Type 1; Stromal Cells; Testosterone; Tosyl Compounds	2006
Distinct regulation by steroids of messenger RNAs for FSHR and CYP19A1 in bovine granulosa cells. Biology of reproduction, 2006, Volume: 75, Issue:2 Topics: Analysis of Variance; Anilides; Animals; Aromatase; Cattle; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Follicle Stimulating Hormone; Fulvestrant; Gene Expression Regulation; Granulosa Cells; Nitriles; Receptors, Androgen; Receptors, FSH; RNA, Messenger; Steroids; Testosterone; Tosyl Compounds	2006
Ligand-specific dynamics of the androgen receptor at its response element in living cells. Molecular and cellular biology, 2007, Volume: 27, Issue:5 Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Animals; Cell Line, Tumor; Chromatin Assembly and Disassembly; Cyproterone Acetate; Dihydrotestosterone; Female; Fluorescence Recovery After Photobleaching; Flutamide; Genes, Reporter; Green Fluorescent Proteins; In Situ Hybridization, Fluorescence; Ligands; Luciferases; Mammary Neoplasms, Animal; Mammary Tumor Virus, Mouse; Metribolone; Mice; Microscopy, Video; Mifepristone; Models, Biological; Nitriles; Plasmids; Promoter Regions, Genetic; Receptors, Androgen; Response Elements; Testosterone; Tosyl Compounds; Transcription, Genetic	2007
The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay. Biochemistry, 2007, Jan-23, Volume: 46, Issue:3 Topics: Amino Acid Sequence; Amino Acid Substitution; Androgen Antagonists; Anilides; Animals; Cyproterone Acetate; Dihydrotestosterone; Fluoresceins; Fluorescence Resonance Energy Transfer; Flutamide; Ligands; Mifepristone; Nitriles; Oligopeptides; Rats; Receptors, Androgen; Tosyl Compounds	2007
Non-steroidal antiandrogens act as AF-1 agonists under conditions of high androgen-receptor expression. The Prostate, 2007, May-01, Volume: 67, Issue:6 Topics: Androgens; Anilides; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Flutamide; HeLa Cells; Humans; Male; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Receptors, Interferon; Tosyl Compounds; Transcriptional Activation	2007
Reactive oxygen species mediate androgen receptor- and serum starvation-elicited downstream signaling of ADAM9 expression in human prostate cancer cells. The Prostate, 2007, May-15, Volume: 67, Issue:7 Topics: ADAM Proteins; Androgen Antagonists; Androgens; Anilides; Catalase; Cell Line, Tumor; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Male; Membrane Proteins; Nitriles; Prostatic Neoplasms; Reactive Oxygen Species; Receptors, Androgen; Serum; Signal Transduction; Tosyl Compounds; Transfection	2007
Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia. The Prostate, 2007, Jul-01, Volume: 67, Issue:10 Topics: Adult; Aged; Androgens; Anilides; Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Cell Hypoxia; Cell Line, Tumor; Dihydrotestosterone; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Repressor Proteins; Signal Transduction; Tosyl Compounds; Vascular Endothelial Growth Factor A	2007
Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide. Proceedings of the National Academy of Sciences of the United States of America, 2007, Jun-19, Volume: 104, Issue:25 Topics: Androgen Antagonists; Androgens; Anilides; Base Pair Mismatch; Base Pairing; Base Sequence; Cell Line, Tumor; Dihydrotestosterone; DNA; Gene Expression Regulation, Neoplastic; Humans; Male; Molecular Sequence Data; Nitriles; Nylons; Phthalic Acids; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Response Elements; RNA, Messenger; Tosyl Compounds	2007
In vitro and in vivo effects of bicalutamide on the expression of TrkA and P75 neurotrophin receptors in prostate carcinoma. The Prostate, 2007, Sep-01, Volume: 67, Issue:12 Topics: Adult; Aged; Androgen Antagonists; Anilides; Antineoplastic Agents; Blotting, Western; Carbazoles; Carcinoma; Cell Line, Tumor; Cohort Studies; Dihydrotestosterone; Furans; Humans; Immunohistochemistry; Indoles; Male; Middle Aged; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Protein Kinase Inhibitors; Receptor, Nerve Growth Factor; Receptor, trkA; Receptor, trkC; Tosyl Compounds	2007
A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells. Molecular cancer therapeutics, 2007, Volume: 6, Issue:7 Topics: Androgen Receptor Antagonists; Androgens; Anilides; Antineoplastic Agents; Cell Proliferation; Dihydrotestosterone; Drug Resistance, Neoplasm; Drug Synergism; Flutamide; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Imidazolidines; Male; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tosyl Compounds; Transcription, Genetic	2007
Androgen receptor-mediated repression of novel target genes. The Prostate, 2007, Sep-15, Volume: 67, Issue:13 Topics: Androgen Antagonists; Anilides; Cell Line, Tumor; Cycloheximide; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Humans; Male; Nitriles; Prostatic Neoplasms; Protein Synthesis Inhibitors; Receptor, Muscarinic M1; Receptors, Androgen; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tosyl Compounds; Transfection	2007
Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines. The Prostate, 2008, Feb-15, Volume: 68, Issue:3 Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Basic Helix-Loop-Helix Transcription Factors; Cell Hypoxia; Cell Line, Tumor; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Kaplan-Meier Estimate; Male; Membrane Proteins; Middle Aged; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Proto-Oncogene Proteins; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Tosyl Compounds	2008
Nevirapine restores androgen signaling in hormone-refractory human prostate carcinoma cells both in vitro and in vivo. The Prostate, 2009, May-15, Volume: 69, Issue:7 Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Animals; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Dihydrotestosterone; Docetaxel; Drug Synergism; Humans; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Nevirapine; Nitriles; Prostatic Neoplasms; Random Allocation; Receptors, Androgen; Reverse Transcriptase Inhibitors; RNA, Neoplasm; Signal Transduction; Taxoids; Tosyl Compounds; Xenograft Model Antitumor Assays	2009
Systematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H. The Journal of biological chemistry, 2010, Feb-12, Volume: 285, Issue:7 Topics: Androgen Antagonists; Anilides; Blotting, Western; Cell Line, Tumor; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Humans; Hydrocortisone; Hydrophobic and Hydrophilic Interactions; Male; Mutation; Nitriles; Progesterone; Prostatic Neoplasms; Protein Structure, Secondary; Receptors, Androgen; Steroids; Structure-Activity Relationship; Tosyl Compounds	2010
Prolonged treatment with bicalutamide induces androgen receptor overexpression and androgen hypersensitivity. The Prostate, 2010, May-15, Volume: 70, Issue:7 Topics: Androgen Antagonists; Anilides; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Dihydrotestosterone; Enzyme-Linked Immunosorbent Assay; Male; Mice; Nitriles; Prostate; Prostate-Specific Antigen; Receptors, Androgen; Testosterone; Time Factors; Tosyl Compounds	2010
AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model. Journal of cellular biochemistry, 2010, Aug-01, Volume: 110, Issue:5 Topics: Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dihydrotestosterone; Drug Synergism; Gossypol; Humans; Immunoblotting; Male; Nitriles; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptors, Androgen; Tosyl Compounds	2010
An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy. The Journal of biological chemistry, 2010, Nov-12, Volume: 285, Issue:46 Topics: Amino Acid Motifs; Amino Acid Sequence; Androgen Antagonists; Androgens; Anilides; Animals; Binding Sites; Blotting, Western; Bulbo-Spinal Atrophy, X-Linked; Cells, Cultured; Dihydrotestosterone; HEK293 Cells; Humans; Mice; Mice, Transgenic; Microscopy, Fluorescence; Motor Neurons; Mutation; Nitriles; PC12 Cells; Protein Binding; Rats; Receptors, Androgen; Testosterone; Tosyl Compounds; Trinucleotide Repeat Expansion; Two-Hybrid System Techniques	2010
Androgen stimulates endothelial cell proliferation via an androgen receptor/VEGF/cyclin A-mediated mechanism. American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:4 Topics: Androgen Receptor Antagonists; Anilides; Aorta; Cell Proliferation; Cells, Cultured; Cyclin A; Dihydrotestosterone; DNA; Endothelium, Vascular; Estradiol; Gene Expression; Humans; Indoles; Male; Nitriles; Protein Kinase Inhibitors; Purines; Pyrroles; Receptors, Androgen; Roscovitine; Testosterone; Tosyl Compounds; Vascular Endothelial Growth Factor A	2011
The antiandrogenic effect of finasteride against a mutant androgen receptor. Cancer biology & therapy, 2011, May-15, Volume: 11, Issue:10 Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Finasteride; Gene Expression Regulation; Gene Knockdown Techniques; Homeodomain Proteins; Humans; Mutation; Nitriles; Receptors, Androgen; Tosyl Compounds	2011
Mechanism of androgen receptor antagonism by bicalutamide in the treatment of prostate cancer. Biochemistry, 2011, May-17, Volume: 50, Issue:19 Topics: Androgen Receptor Antagonists; Anilides; Dihydrotestosterone; Energy Metabolism; Humans; Ligands; Molecular Dynamics Simulation; Nitriles; Protein Binding; Protein Folding; Protein Structure, Tertiary; Quantum Theory; Receptors, Androgen; Tosyl Compounds	2011
Influence of short polyglutamine tracts and p160 coactivators on the transactivation of the androgen receptor. Cancer biotherapy & radiopharmaceuticals, 2011, Volume: 26, Issue:2 Topics: Androgen Antagonists; Anilides; Dihydrotestosterone; Humans; Luciferases; Male; Mutation; Nitriles; Nuclear Receptor Coactivator 2; Nuclear Receptor Coactivators; Peptides; Prostatic Neoplasms; Receptors, Androgen; Saccharomyces cerevisiae; Tosyl Compounds; Transcriptional Activation; Up-Regulation	2011
Targeting androgen receptor in estrogen receptor-negative breast cancer. Cancer cell, 2011, Jul-12, Volume: 20, Issue:1 Topics: Androgens; Anilides; Animals; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 3-alpha; Humans; Mice; Nitriles; Receptor, ErbB-2; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Tosyl Compounds; Transcriptional Activation; Up-Regulation; Wnt Proteins; Xenograft Model Antitumor Assays	2011
Androgens regulate Hedgehog signalling and proliferation in androgen-dependent prostate cells. International journal of cancer, 2012, Sep-15, Volume: 131, Issue:6 Topics: Adult; Anilides; Cell Line, Tumor; Cell Proliferation; Cinnamates; Dihydrotestosterone; Hedgehog Proteins; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tosyl Compounds; Veratrum Alkaloids	2012
Dihydrotestosterone and bicalutamide do not affect periostin expression in androgen-dependent LNCaP prostate cancer cell lines. Anticancer research, 2013, Volume: 33, Issue:3 Topics: Androgens; Anilides; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; RNA, Messenger; Tosyl Compounds	2013
Bone morphogenetic protein-6 induces castration resistance in prostate cancer cells through tumor infiltrating macrophages. Cancer science, 2013, Volume: 104, Issue:8 Topics: Androgen Receptor Antagonists; Androgens; Anilides; Animals; Benzamides; Benzofurans; Bone Morphogenetic Protein 6; Cell Line, Tumor; Dihydrotestosterone; Humans; Interleukin-6; Lymphocytes, Tumor-Infiltrating; Macrophages; Male; Mice; Nitriles; Phenylthiohydantoin; Promoter Regions, Genetic; Prostatic Neoplasms, Castration-Resistant; Quinolines; Receptors, Androgen; Tosyl Compounds; Up-Regulation	2013
Antiandrogenic actions of medroxyprogesterone acetate on epithelial cells within normal human breast tissues cultured ex vivo. Menopause (New York, N.Y.), 2014, Volume: 21, Issue:1 Topics: Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Breast; Bromodeoxyuridine; Cell Proliferation; Dihydrotestosterone; Epithelial Cells; Estrogen Receptor alpha; Female; Humans; Ki-67 Antigen; Medroxyprogesterone Acetate; Nitriles; Postmenopause; Premenopause; Proto-Oncogene Proteins c-bcl-2; Receptors, Androgen; Receptors, Progesterone; Signal Transduction; Tissue Culture Techniques; Tosyl Compounds	2014
Androgen-independent proliferation of LNCaP prostate cancer cells infected by xenotropic murine leukemia virus-related virus. Biochemical and biophysical research communications, 2014, Apr-25, Volume: 447, Issue:1 Topics: Androgen Receptor Antagonists; Androgens; Anilides; Animals; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Humans; Male; Mice; Nitriles; Prostatic Neoplasms; Rats; Receptors, Androgen; Tosyl Compounds; Xenotropic murine leukemia virus-related virus	2014
Accumulation of trans-1-amino-3-[(18)F]fluorocyclobutanecarboxylic acid in prostate cancer due to androgen-induced expression of amino acid transporters. Molecular imaging and biology, 2014, Volume: 16, Issue:6 Topics: Amino Acid Transport Systems; Androgens; Anilides; Carboxylic Acids; Cell Line, Tumor; Cyclobutanes; Dihydrotestosterone; Fluorine Radioisotopes; Gene Expression Regulation, Neoplastic; Humans; Male; Nitriles; Prostatic Neoplasms, Castration-Resistant; Radioactive Tracers; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Androgen; Tosyl Compounds	2014
The oncogenic role of androgen receptors in promoting the growth of oral squamous cell carcinoma cells. Oral diseases, 2015, Volume: 21, Issue:3 Topics: Androgen Antagonists; Androgens; Anilides; Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Dihydrotestosterone; Gene Knockdown Techniques; Humans; Mice; Mouth Neoplasms; Nitriles; Precancerous Conditions; Receptors, Androgen; Tosyl Compounds	2015
Effects of treatment with androgen receptor ligands on microRNA expression of prostate cancer cells. Toxicology, 2015, Jul-03, Volume: 333 Topics: Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Ligands; Male; MicroRNAs; Nandrolone; Neoplasms, Hormone-Dependent; Nitriles; Oligonucleotide Array Sequence Analysis; Prostate-Specific Antigen; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Time Factors; Tosyl Compounds	2015
FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer. Oncotarget, 2015, Oct-06, Volume: 6, Issue:30 Topics: Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents; Benzamides; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 3-alpha; Humans; Kallikreins; Male; Mutation; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tosyl Compounds	2015
Androgen receptor functions as a negative transcriptional regulator of DEPTOR, mTOR inhibitor. The Journal of toxicological sciences, 2015, Volume: 40, Issue:6 Topics: Androgen Antagonists; Anilides; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Dihydrotestosterone; Histones; Humans; Intracellular Signaling Peptides and Proteins; Male; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptor Cross-Talk; Receptors, Androgen; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Tosyl Compounds; Transcription, Genetic; Tumor Cells, Cultured	2015
Antiproliferative Effect of Androgen Receptor Inhibition in Mesenchymal Stem-Like Triple-Negative Breast Cancer. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:3 Topics: Anilides; Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Dihydrotestosterone; Female; Gene Expression Regulation; Humans; Mice; Neoplasm Transplantation; Nitriles; Receptors, Androgen; Tosyl Compounds; Triple Negative Breast Neoplasms; Tumor Protein p73	2016
The fluorescent two-hybrid assay for live-cell profiling of androgen receptor modulators. The Journal of steroid biochemistry and molecular biology, 2017, Volume: 166 Topics: Androgen Antagonists; Androgens; Androstadienes; Androstenes; Anilides; Animals; Benzamides; Benzimidazoles; Biological Assay; Cell Line; Cricetinae; Dihydrotestosterone; Flutamide; HEK293 Cells; Humans; Male; Microscopy, Fluorescence; Mutation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Transcription Factors; Two-Hybrid System Techniques	2017
Corepressive function of nuclear receptor coactivator 2 in androgen receptor of prostate cancer cells treated with antiandrogen. BMC cancer, 2016, 05-25, Volume: 16 Topics: Androgen Antagonists; Anilides; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Mutation; Nitriles; Nuclear Receptor Coactivators; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds	2016
Enzalutamide inhibits androgen receptor-positive bladder cancer cell growth. Urologic oncology, 2016, Volume: 34, Issue:10 Topics: Androgen Antagonists; Anilides; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dihydrotestosterone; Down-Regulation; Flutamide; Humans; Interleukin-6; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Nitriles; Phenylthiohydantoin; Receptors, Androgen; RNA; Tosyl Compounds; Transcription, Genetic; Urinary Bladder Neoplasms	2016
NADPH Oxidase Mediates Membrane Androgen Receptor-Induced Neurodegeneration. Endocrinology, 2019, 04-01, Volume: 160, Issue:4 Topics: Androgen Receptor Antagonists; Anilides; Animals; Cell Line; Cell Survival; Dihydrotestosterone; Hydrogen Peroxide; Neurons; Nitriles; Oxidative Stress; Rats; Receptors, Androgen; Receptors, Cell Surface; Signal Transduction; Testosterone; Tosyl Compounds	2019
Androgen promotes differentiation of PLZF Cell communication and signaling : CCS, 2019, 05-29, Volume: 17, Issue:1 Topics: Androgen Antagonists; Androgens; Anilides; Animals; Cadherins; Cell Differentiation; Cells, Cultured; Dihydrotestosterone; GATA2 Transcription Factor; Integrin beta1; Male; Mice; Nitriles; Promyelocytic Leukemia Zinc Finger Protein; Spermatogonia; Tosyl Compounds; WT1 Proteins	2019
Structural Dynamics of Agonist and Antagonist Binding to the Androgen Receptor. The journal of physical chemistry. B, 2019, 09-12, Volume: 123, Issue:36 Topics: Androgen Receptor Antagonists; Androgens; Anilides; Binding Sites; Dihydrotestosterone; Flutamide; Humans; Molecular Dynamics Simulation; Nitriles; Receptors, Androgen; Testosterone; Tosyl Compounds	2019
Glutaminolysis is a metabolic route essential for survival and growth of prostate cancer cells and a target of 5α-dihydrotestosterone regulation. Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:2 Topics: Amino Acid Transport System ASC; Androgens; Anilides; Animals; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Glucose; Glutaminase; Glutamine; Glycolysis; Humans; Lactic Acid; Lipid Metabolism; Male; Minor Histocompatibility Antigens; Models, Biological; Neoplasm Proteins; Nitriles; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rats; Sulfides; Thiadiazoles; Tosyl Compounds	2021
Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 137 Topics: Alopecia; Androgen Antagonists; Anilides; Animals; Dihydrotestosterone; Disease Models, Animal; Hair Follicle; Male; Mice; Mice, Inbred C57BL; Nitriles; Organ Culture Techniques; Receptors, Androgen; Signal Transduction; Tosyl Compounds	2021
Conformational dynamics of androgen receptors bound to agonists and antagonists. Scientific reports, 2021, 08-05, Volume: 11, Issue:1 Topics: Androgen Receptor Antagonists; Androgens; Anilides; Benzamides; Binding Sites; Dihydrotestosterone; Humans; Imidazoles; Ligands; Molecular Conformation; Molecular Dynamics Simulation; Nitriles; Phenylthiohydantoin; Principal Component Analysis; Protein Binding; Protein Conformation; Receptors, Androgen; Thiohydantoins; Tosyl Compounds	2021