bicalutamide and apalutamide

bicalutamide has been researched along with apalutamide in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (44.44)24.3611
2020's5 (55.56)2.80

Authors

AuthorsStudies
Chen, C; Jung, ME; Ouk, S; Sawyers, CL; Tran, C; Wongvipat, J; Yoo, D1
Chufarova, NV; Ivachtchenko, AV; Ivanenkov, YA; Karapetian, RN; Koryakova, AG; Kravchenko, DV; Kuznetsova, IV; Mitkin, OD; Shevkun, NA; Trifelenkov, AS; Veselov, MS; Vorobiev, AA1
Wang, S; Xiang, W1
Aparicio, A; Arora, V; Bischoff, ED; Bonnefous, C; Cai, L; Cao, C; Chen, Y; Clegg, NJ; Darimont, B; De Stanchina, E; Dilhas, A; Dorow, S; Grillot, K; Hager, JH; Herbert, MR; Heyman, RA; Joseph, JD; Jung, ME; Klang, M; Ouerfelli, O; Ouk, S; Qian, J; Rix, PJ; Sawyers, CL; Scher, HI; Sensintaffar, J; Shao, G; Smith, ND; Smith-Jones, P; Tran, C; Wasielewska, T; Wongvipat, J; Wu, N; Yang, G; Zhao, H1
Fasoulaki, V; Giatromanolaki, A; Kakouratos, C; Kalamida, D; Koukourakis, MI; Mitrakas, A; Papadopoulou, E; Pouliliou, S; Xanthopoulou, E1
Kolesar, JM; Momo, HD; Myint, ZW; Otto, DE; Wang, P; Yan, D1
Gim, HJ; Houk, KN; Jung, ME; Park, J1
Giatromanolaki, A; Kakouratos, C; Kalamida, D; Koukourakis, MI; Lamprou, I; Nanos, C; Xanthopoulou, E1
Cardoso, AM; Maia, CJ; Nascimento, D; Passarinha, L; Rocha, SM; Socorro, S1

Reviews

2 review(s) available for bicalutamide and apalutamide

ArticleYear
Therapeutic Strategies to Target the Androgen Receptor.
    Journal of medicinal chemistry, 2022, 07-14, Volume: 65, Issue:13

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen

2022
Evaluation of Fall and Fracture Risk Among Men With Prostate Cancer Treated With Androgen Receptor Inhibitors: A Systematic Review and Meta-analysis.
    JAMA network open, 2020, 11-02, Volume: 3, Issue:11

    Topics: Abiraterone Acetate; Accidental Falls; Androgen Receptor Antagonists; Anilides; Antineoplastic Agents, Hormonal; Benzamides; Case-Control Studies; Fractures, Bone; Humans; Incidence; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Pyrazoles; Risk Factors; Thiohydantoins; Tosyl Compounds; Trauma Severity Indices

2020

Other Studies

7 other study(ies) available for bicalutamide and apalutamide

ArticleYear
Structure-activity relationship for thiohydantoin androgen receptor antagonists for castration-resistant prostate cancer (CRPC).
    Journal of medicinal chemistry, 2010, Apr-08, Volume: 53, Issue:7

    Topics: Androgen Receptor Antagonists; Androgens; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Male; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Structure-Activity Relationship; Thiohydantoins; Tumor Burden; Xenograft Model Antitumor Assays

2010
Design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists.
    European journal of medicinal chemistry, 2015, Jun-24, Volume: 99

    Topics: Androgen Receptor Antagonists; Animals; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Drug Design; Humans; Imidazolidines; Male; Molecular Docking Simulation; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Androgen

2015
ARN-509: a novel antiandrogen for prostate cancer treatment.
    Cancer research, 2012, Mar-15, Volume: 72, Issue:6

    Topics: Androgen Antagonists; Anilides; Animals; Antineoplastic Agents, Hormonal; Benzamides; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Rats; Receptors, Androgen; Thiohydantoins; Tosyl Compounds; Xenograft Model Antitumor Assays

2012
Comparison of the effect of the antiandrogen apalutamide (ARN-509) versus bicalutamide on the androgen receptor pathway in prostate cancer cell lines.
    Anti-cancer drugs, 2018, Volume: 29, Issue:4

    Topics: Androgen Antagonists; Anilides; Autophagy; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Male; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Thiohydantoins; Tosyl Compounds

2018
Conformational dynamics of androgen receptors bound to agonists and antagonists.
    Scientific reports, 2021, 08-05, Volume: 11, Issue:1

    Topics: Androgen Receptor Antagonists; Androgens; Anilides; Benzamides; Binding Sites; Dihydrotestosterone; Humans; Imidazoles; Ligands; Molecular Conformation; Molecular Dynamics Simulation; Nitriles; Phenylthiohydantoin; Principal Component Analysis; Protein Binding; Protein Conformation; Receptors, Androgen; Thiohydantoins; Tosyl Compounds

2021
Apalutamide radio-sensitisation of prostate cancer.
    British journal of cancer, 2021, Volume: 125, Issue:10

    Topics: Anilides; Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemoradiotherapy; Dose-Response Relationship, Radiation; Humans; Male; Mice; Nitriles; PC-3 Cells; Prostatic Neoplasms; Radiation-Sensitizing Agents; Thiohydantoins; Tosyl Compounds; Xenograft Model Antitumor Assays

2021
STEAP1 regulation and its influence modulating the response of LNCaP prostate cancer cells to bicalutamide, enzalutamide and apalutamide.
    Molecular medicine reports, 2023, Volume: 27, Issue:2

    Topics: Androgen Antagonists; Antigens, Neoplasm; Humans; Male; Nitriles; Oxidoreductases; Prostate; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant

2023