Page last updated: 2024-09-03

bibw 22 and fluorouracil

bibw 22 has been researched along with fluorouracil in 2 studies

Compound Research Comparison

Studies
(bibw 22)
Trials
(bibw 22)
Recent Studies (post-2010)
(bibw 22)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
60045,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomybibw 22 (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bamberger, U; Chen, HX; Cheng, YC; Guo, X; Heckel, A1
Bamberger, U; Boven, E; Feller, N; Jansen, WJ; Pinedo, HM; van der Wilt, CL1

Other Studies

2 other study(ies) available for bibw 22 and fluorouracil

ArticleYear
BIBW 22, a dipyridamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport.
    Cancer research, 1993, May-01, Volume: 53, Issue:9

    Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Membrane Permeability; Dipyridamole; Drug Synergism; Fluorouracil; Humans; Membrane Glycoproteins; Morpholines; Nucleosides; Photochemistry; Thymidine; Triamterene; Tumor Cells, Cultured; Vincristine

1993
The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and gemcitabine in vitro and in human tumour xenografts.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:13-14

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Deoxycytidine; Dipyridamole; Doxorubicin; Drug Resistance; Female; Floxuridine; Fluorouracil; Gemcitabine; Humans; Methotrexate; Mice; Mice, Nude; Morpholines; Neoplasms; Neoplasms, Experimental; Protein Binding; Transplantation, Heterologous; Triamterene; Tumor Cells, Cultured; Vincristine

1995