Compounds > bibw 22
Page last updated: 2024-09-03

bibw 22 and dipyridamole

bibw 22 has been researched along with dipyridamole in 3 studies

Compound Research Comparison

Studies
(bibw 22)		Trials
(bibw 22)		Recent Studies (post-2010)
(bibw 22)		Studies
(dipyridamole)		Trials
(dipyridamole)		Recent Studies (post-2010) (dipyridamole)
6007,826881632

Protein Interaction Comparison

ProteinTaxonomybibw 22 (IC50)dipyridamole (IC50)
90-kda heat shock protein beta HSP90 beta, partialHomo sapiens (human)21.0682
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)21.0682
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1233
Solute carrier family 22 member 2Homo sapiens (human)2.6
Multidrug resistance-associated protein 4Homo sapiens (human)5.15
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)2.6333
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.9708
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)5.835
Bile salt export pumpHomo sapiens (human)4
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)6.956
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)2.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.6333
Exopolyphosphatase PRUNE1Homo sapiens (human)0.78
Equilibrative nucleoside transporter 1Homo sapiens (human)0.0537
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)6.4

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bamberger, U; Boven, E; Heckel, A; Jansen, WJ; Kuiper, CM; Lincke, C; Pinedo, HM1
Bamberger, U; Chen, HX; Cheng, YC; Guo, X; Heckel, A1
Bamberger, U; Boven, E; Feller, N; Jansen, WJ; Pinedo, HM; van der Wilt, CL1

Other Studies

3 other study(ies) available for bibw 22 and dipyridamole

ArticleYear
Biochemical modulation of 'classical' multidrug resistance by BIBW22BS, a potent derivative of dipyridamole.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:8

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dipyridamole; Doxorubicin; Drug Resistance, Multiple; Female; Humans; Mice; Mice, Nude; Morpholines; Neoplasm Transplantation; Neoplasms, Experimental; Triamterene; Tumor Cells, Cultured; Vincristine

1994
BIBW 22, a dipyridamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport.
    Cancer research, 1993, May-01, Volume: 53, Issue:9

    Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Membrane Permeability; Dipyridamole; Drug Synergism; Fluorouracil; Humans; Membrane Glycoproteins; Morpholines; Nucleosides; Photochemistry; Thymidine; Triamterene; Tumor Cells, Cultured; Vincristine

1993
The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and gemcitabine in vitro and in human tumour xenografts.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:13-14

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Deoxycytidine; Dipyridamole; Doxorubicin; Drug Resistance; Female; Floxuridine; Fluorouracil; Gemcitabine; Humans; Methotrexate; Mice; Mice, Nude; Morpholines; Neoplasms; Neoplasms, Experimental; Protein Binding; Transplantation, Heterologous; Triamterene; Tumor Cells, Cultured; Vincristine

1995