bibs 39 has been researched along with losartan in 6 studies
| Studies (bibs 39) | Trials (bibs 39) | Recent Studies (post-2010) (bibs 39) | Studies (losartan) | Trials (losartan) | Recent Studies (post-2010) (losartan) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 7,231 | 1,245 | 2,118 |
| Protein | Taxonomy | bibs 39 (IC50) | losartan (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 9.01 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2.882 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.019 | |
| Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.0018 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.019 | |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0247 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0234 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.0032 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 0.047 | |
| Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | 0.025 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0118 | |
| Type-2 angiotensin II receptor | Homo sapiens (human) | 0.019 | |
| Platelet glycoprotein VI | Homo sapiens (human) | 4 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.1481 | |
| Type-1 angiotensin II receptor | Cavia porcellus (domestic guinea pig) | 0.018 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.2884 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Entzeroth, M; Hasselbach, KM; Hauel, NH; Mihm, G; Narr, B; Ries, UJ; van Meel, JC; Wienen, W; Wittneben, H | 1 |
| Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR | 1 |
| Entzeroth, M; Van Meel, JC; Wienen, W; Zhang, J | 1 |
| Pfaffendorf, M; van Zwieten, PA; Zhang, J | 2 |
| Van Meel, JC; Van Zwieten, PA; Zhang, J | 1 |
1 review(s) available for bibs 39 and losartan
| Article | Year |
|---|---|
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship | 1996 |
5 other study(ies) available for bibs 39 and losartan
| Article | Year |
|---|---|
6-Substituted benzimidazoles as new nonpeptide angiotensin II receptor antagonists: synthesis, biological activity, and structure-activity relationships.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Benzoates; Binding Sites; Blood Pressure; Male; Models, Molecular; Rats; Rats, Wistar; Receptors, Angiotensin; Structure-Activity Relationship; Telmisartan | 1993 |
Characterization of BIBS 39 and BIBS 222: two new nonpeptide angiotensin II receptor antagonists.
Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Losartan; Male; Methylurea Compounds; Rabbits; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1992 |
Effect of various angiotensin receptor antagonists on cardiovascular responses to angiotensin II in pithed rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiac Output; Cardiovascular Physiological Phenomena; Cardiovascular System; Heart Rate; Imidazoles; Losartan; Male; Methylurea Compounds; Propranolol; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles | 1994 |
Hemodynamic effects of angiotensin II and the influence of angiotensin receptor antagonists in pithed rabbits.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Losartan; Male; Methylurea Compounds; Propranolol; Pyridines; Rabbits; Tetrazoles; Ventricular Function, Left | 1995 |
Antihypertensive activity of the novel, nonpeptide angiotensin II receptor antagonists BIBS 39 and BIBS 222 in conscious renal hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart Rate; Hypertension, Renal; Imidazoles; Losartan; Male; Methylurea Compounds; Rats; Rats, Wistar; Tetrazoles | 1993 |