bibn 99 has been researched along with pirenzepine in 4 studies
*Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients. [MeSH]
*Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients. [MeSH]
| Studies (bibn 99) | Trials (bibn 99) | Recent Studies (post-2010) (bibn 99) | Studies (pirenzepine) | Trials (pirenzepine) | Recent Studies (post-2010) (pirenzepine) |
|---|---|---|---|---|---|
| 11 | 0 | 0 | 3,812 | 587 | 140 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aubert, I; Doods, H; Meaney, MJ; Parent, A; Quirion, R; Richard, J; Rowe, W; White, N; Wilson, A | 1 |
| Doods, H; Eberlein, W; Engel, W; Entzeroth, M; Mihm, G; Rudolf, K; Schiavi, G; Ziegler, H | 1 |
| Bechtel, WD; Doods, HN; Engel, W; Ensinger, HA; Entzeroth, M; Ladinsky, H; Mihm, G; Quirion, R; Rudolf, K; Schiavi, GB | 1 |
| Hirano, S; Kakefuda, A; Shibata, H; Takizawa, K; Tanaka, A; Watanabe, T; Yamagiwa, Y; Yanagisawa, I | 1 |
1 review(s) available for bibn 99 and pirenzepine
| Article | Year |
|---|---|
Therapeutic potential of CNS-active M2 antagonists: novel structures and pharmacology.
Topics: Animals; Benzodiazepinones; Brain; CHO Cells; Cognition Disorders; Cricetinae; Dibenzazepines; Drug Design; Motor Activity; Parasympatholytics; Piperidines; Pirenzepine; Pyridines; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 1993 |
3 other study(ies) available for bibn 99 and pirenzepine
| Article | Year |
|---|---|
Facilitation of acetylcholine release and cognitive performance by an M(2)-muscarinic receptor antagonist in aged memory-impaired.
Topics: Acetylcholine; Aging; Animals; Cognition; Dibenzazepines; Male; Maze Learning; Memory Disorders; Muscarinic Antagonists; Parasympatholytics; Pirenzepine; Pyridines; Rats; Rats, Inbred Strains; Scopolamine | 1995 |
Characterization of BIBN 99: a lipophilic and selective muscarinic M2 receptor antagonist.
Topics: Animals; Binding Sites; Dibenzazepines; Guinea Pigs; Heart; Hemodynamics; Male; Muscarinic Antagonists; Muscle, Smooth; Myocardium; Parasympatholytics; Pirenzepine; Pyridines; Rabbits; Rats; Rats, Wistar; Receptors, Muscarinic | 1993 |
Synthesis and biological evaluation of phenylacetyl derivatives having low central nervous system permeability as potent and selective M2 muscarinic receptor antagonists.
Topics: Animals; Bradycardia; Cerebral Cortex; Dibenzazepines; Dogs; Heart; Male; Mice; Muscarinic Antagonists; Parasympatholytics; Phenylacetates; Pirenzepine; Pyridines; Rats; Rats, Wistar; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Salivation; Structure-Activity Relationship; Submandibular Gland; Tremor | 1998 |