biapigenin has been researched along with pevonedistat* in 1 studies
1 other study(ies) available for biapigenin and pevonedistat
Article | Year |
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A natural product-like inhibitor of NEDD8-activating enzyme.
The natural product-like 6,6″-biapigenin has been identified as only the second inhibitor of NEDD8-activating enzyme using virtual screening. This compound was active in enzyme and cell-based assays, with potency in the micromolar range. Topics: Apigenin; Biflavonoids; Binding Sites; Cell Line, Tumor; Computer Simulation; Cyclopentanes; Drug Design; Humans; NEDD8 Protein; Pyrimidines; Ubiquitins | 2011 |