Page last updated: 2024-08-23

bezafibrate and ursodeoxycholic acid

bezafibrate has been researched along with ursodeoxycholic acid in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (12.90)29.6817
2010's38 (61.29)24.3611
2020's16 (25.81)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Deguchi, A; Kurokohchi, K; Masaki, T; Nakai, S; Nishioka, M1
Kurihara, T; Maeda, A; Niimi, A; Shigemoto, M; Yamashita, K1
Mitsui, Y; Ohmoto, K; Yamamoto, S1
Fukuyama, T; Hachiya, T; Hatano, H; Kimura, T; Kita, R; Kokuryu, H; Komekado, H; Komibuchi, T; Maruo, T; Osaki, Y; Sawabu, T; Shimizu, T; Takamatsu, S; Tomono, N; Tsuji, K1
Imazeki, F; Kanda, T; Saisho, H; Yokosuka, O1
Zeniya, M1
Lengyel, G; Tulassay, Z1
Bassendine, MF; Jones, DE; Newton, J; Walker, LJ1
Fujioka, S; Ikeda, F; Itoshima, T; Iwasaki, Y; Kobashi, H; Miyake, Y; Osawa, T; Takaki, A; Takaki, T; Takeuchi, Y; Yamamoto, K; Yasunaka, T1
Abe, K; Kanno, Y; Katsushima, F; Monoe, K; Ohira, H; Saito, H; Takahashi, A; Yokokawa, J1
Chapman, RW; Halliday, JS1
Bjelakovic, G; Gluud, C; Krstic, MN; Poropat, G; Rudic, JS1
Hirayama, T; Honda, A; Ikegami, T; Imawari, M; Iwamoto, J; Matsuzaki, Y; Miyazaki, T; Nakamuta, M; Saito, Y; Takikawa, H1
Boyer, JL; Ghonem, NS1
Tanaka, A1
Bruguera, M; Lens, S; Leoz, M; Nazal, L; Parés, A1
Dohmen, K; Haruno, M; Tanaka, H1
Ando, M; Harada, K; Hirohata, M; Miyake, Y; Moriya, A; Nakanuma, Y; Takemoto, R; Yamamoto, K1
Hirohara, J; Nakanuma, Y; Takikawa, H; Tanaka, A; Tsubouchi, H1
Hashizume, H; Horiguchi, N; Hosonuma, K; Kakizaki, S; Kusano, M; Sato, K; Yamada, M; Yamazaki, Y; Yanagisawa, M1
Braddock, M; Chen, YP; Huang, GQ; Huang, S; Lin, YQ; Shi, KQ; Wang, JT; Wang, LR; Wu, YM; Zheng, MH; Zhou, MT; Zhou, ZR; Zhu, GQ1
Castellaneta, NM; Di Leo, A; Facciorusso, A; Licinio, R1
Hosonuma, K; Kusano, M; Sato, K; Yamada, M1
Abudumijiti, H; Chen, K; Chen, R; Guo, C; Li, J; Li, S; Liu, T; Lu, J; Lu, W; Wang, F; Wang, J; Xia, Y; Yin, Q; Zhang, R; Zheng, Y; Zhou, Y1
Czul, F; Levy, C1
Himoto, T; Iwama, H; Masaki, T; Miyoshi, H; Morishita, A; Nomura, T; Sakamoto, T; Tani, J; Yoneyama, H1
Beuers, U; Hohenester, S1
Parés, A; Reig, A; Sesé, P1
Strassburg, CP1
Levy, C; Lindor, KD1
Abergel, A; Admane, FH; Boursier, J; Bronowicki, JP; Chazouillères, O; Chollet-Martin, S; Corpechot, C; de Chaisemartin, L; de Ledinghen, V; Debette-Gratien, M; Gaouar, F; Goria, O; Habersetzer, F; Heurgue-Berlot, A; Humbert, L; Larrey, D; Le Gruyer, A; Lefèvre, G; Lemoinne, S; Mathurin, P; Minello, A; Nguyen-Khac, E; Nkontchou, G; Ollivier-Hourmand, I; Potier, P; Poupon, R; Rainteau, D; Rousseau, A; Roux, O; Silvain, C; Simon, T; Zarski, JP; Zoulim, F1
Düll, MM; Kremer, AE1
Ben Belkacem, K; Chazouillères, O; Corpechot, C; Gaouar, F; Housset, C; Kemgang Fankem, AD; Lemoinne, S; Pares, A; Poupon, R; Reig, A1
Poupon, R1
Hegade, VS; Jones, DE1
Bahar, R; Bowlus, CL; Liu, CH; Wong, KA1
Korula, J1
Klose, G; Nitschmann, S1
Chazouillères, O; Corpechot, C; Lemoinne, S; Rousseau, A1
Abe, M; Arakawa, M; Fujii, H; Hashimoto, N; Honda, A; Iimuro, S; Inao, M; Itakura, J; Joshita, S; Kakisaka, K; Kaneko, A; Kaneko, T; Kang, JH; Kawada, N; Kawata, K; Kikuchi, K; Komori, A; Masaki, T; Matsuzaki, Y; Mochida, S; Namisaki, T; Ninomiya, M; Nomura, T; Ohira, H; Sato, K; Takahashi, A; Takikawa, H; Takikawa, Y; Tanaka, A; Umemura, T; Yamagiwa, S; Yoshiji, H1
Feng, BL; Shen, W; Yu, HH1
Chang, Y; Cho, EJ; Chung, SW; Kim, MA; Kim, SW; Kim, YJ; Lee, HY; Lee, JH; Lee, YB; Leem, G; Park, JY; Yoon, JH; Yoon, JS; Yu, SJ1
Amano, K; Hidaka, A; Ishida, J; Ishikawa, T; Mizuno, Y; Nakano, M; Oikawa, T; Saeki, C; Saruta, M; Takakura, K; Takano, K; Torisu, Y; Tsubota, A; Zeniya, M1
Kowdley, KV; Shah, RA1
Chazouillères, O; Corpechot, C; Rousseau, A1
Harms, MH; van Buuren, HR; van der Meer, AJ1
de Veer, RC; Laschtowitz, A; Schramm, C; Van der Meer, AJ1
Abe, M; Aiso, M; Arakawa, M; Arizumi, T; Asaoka, Y; Fujii, H; Hashimoto, N; Honda, A; Inao, M; Itakura, J; Joshita, S; Kakisaka, K; Kaneko, A; Kang, JH; Kawada, N; Kawata, K; Kikuchi, K; Komori, A; Masaki, T; Matsumoto, K; Miura, R; Mochida, S; Namisaki, T; Ninomiya, M; Nomura, T; Ohira, H; Sato, K; Takahashi, A; Takamura, M; Takikawa, H; Takikawa, Y; Tamura, Y; Tanaka, A; Umemura, T; Yagi, M; Yoshiji, H1
Bando, H; Hosoda, W; Matsubara, Y; Muro, K; Niwa, Y; Onishi, S; Tajika, M1
Carrion, AF; Levy, C; Lindor, KD1
Miao, H; Pan, J; Shen, N; Xing, L; Yu, X; Zhang, H1
Avagnina, A; Barreyro, FJ; Carballo, P; Daruich, J; González Ballerga, E; Paes de Lima, A; Sorda, JA1
Lutz, HH; Tischendorf, J1
Barreyro, FJ; Daruich, J; González Ballerga, E; Sorda, JA1
Banales, JM; Rodrigues, PM1
Arizumi, T; Isayama, H; Nakazawa, T; Takikawa, H; Tanaka, A; Tazuma, S; Tsuyuguchi, T1
Khakoo, NS; Levy, C; Reynolds, JM; Sultan, S1
Bowlus, CL; Liu, CH1

Reviews

17 review(s) available for bezafibrate and ursodeoxycholic acid

ArticleYear
[Possibilities in the treatment of primary biliary cirrhosis].
    Orvosi hetilap, 2005, Jun-05, Volume: 146, Issue:23

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Retroviral Agents; Bezafibrate; Eosinophilia; Humans; Hypolipidemic Agents; Immunologic Factors; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Liver Transplantation; Sulindac; Ursodeoxycholic Acid

2005
Bezafibrate for primary biliary cirrhosis.
    The Cochrane database of systematic reviews, 2012, Jan-18, Volume: 1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Bezafibrate; Bilirubin; Drug Therapy, Combination; gamma-Glutamyltransferase; Humans; Hypolipidemic Agents; Immunoglobulin M; Liver Cirrhosis, Biliary; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid

2012
Optimal drug regimens for primary biliary cirrhosis: a systematic review and network meta-analysis.
    Oncotarget, 2015, Sep-15, Volume: 6, Issue:27

    Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Bezafibrate; Bile Ducts; Colchicine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Penicillamine; Treatment Outcome; Ursodeoxycholic Acid

2015
Systematic review and meta-analysis: bezafibrate in patients with primary biliary cirrhosis.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Bezafibrate; Biomarkers; Chi-Square Distribution; Drug Therapy, Combination; Humans; Liver; Liver Cirrhosis, Biliary; Odds Ratio; Risk Factors; Treatment Outcome; Ursodeoxycholic Acid

2015
Novel Therapies on Primary Biliary Cirrhosis.
    Clinics in liver disease, 2016, Volume: 20, Issue:1

    Topics: Abatacept; Anti-Retroviral Agents; Antibodies, Monoclonal, Humanized; Bezafibrate; Chenodeoxycholic Acid; Cholagogues and Choleretics; Fenofibrate; Glucocorticoids; Humans; Hypolipidemic Agents; Immunologic Factors; Liver Cirrhosis, Biliary; Mesenchymal Stem Cell Transplantation; Receptors, Cytoplasmic and Nuclear; Rituximab; Ursodeoxycholic Acid; Ustekinumab

2016
[Chronic cholestatic liver diseases : Differential diagnosis, pathogenesis and current treatment in adults].
    Der Internist, 2017, Volume: 58, Issue:8

    Topics: Adult; Bezafibrate; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Diagnosis, Differential; Humans; Liver Diseases; Ursodeoxycholic Acid

2017
[Modern treatment of primary biliary cholangitis].
    Der Internist, 2018, Volume: 59, Issue:1

    Topics: Bezafibrate; Budesonide; Chenodeoxycholic Acid; Cohort Studies; Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Male; Multicenter Studies as Topic; PPAR alpha; Pregnancy; Prognosis; Quality of Life; Receptors, Cytoplasmic and Nuclear; Risk Assessment; Treatment Outcome; Ursodeoxycholic Acid

2018
Management of Chronic Hepatic Itch.
    Dermatologic clinics, 2018, Volume: 36, Issue:3

    Topics: Analgesics, Opioid; Anion Exchange Resins; Antipruritics; Bezafibrate; Carrier Proteins; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Chronic Disease; Cytochrome P-450 Enzyme Inducers; Drainage; Humans; Hypolipidemic Agents; Membrane Glycoproteins; Methylamines; Narcotic Antagonists; Prevalence; Pruritus; Rifampin; Thiazepines; Ursodeoxycholic Acid

2018
Current Treatment Options for Primary Biliary Cholangitis.
    Clinics in liver disease, 2018, Volume: 22, Issue:3

    Topics: Alkaline Phosphatase; Bezafibrate; Chenodeoxycholic Acid; Cholagogues and Choleretics; Comorbidity; Drug Therapy, Combination; Fenofibrate; Fibroblast Growth Factors; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Malnutrition; Osteoporosis; Peroxisome Proliferator-Activated Receptors; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2018
[Ursodeoxycholic acid combined with bezafibrate in the treatment of refractory primary biliary cholangitis: a meta-analysis].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2019, Apr-20, Volume: 27, Issue:4

    Topics: Bezafibrate; Drug Therapy, Combination; Humans; Liver Cirrhosis, Biliary; Randomized Controlled Trials as Topic; Treatment Outcome; Ursodeoxycholic Acid

2019
Current and potential treatments for primary biliary cholangitis.
    The lancet. Gastroenterology & hepatology, 2020, Volume: 5, Issue:3

    Topics: Benzothiazoles; Bezafibrate; Bile Acids and Salts; Budesonide; Case-Control Studies; Chenodeoxycholic Acid; Cholagogues and Choleretics; Clinical Trials as Topic; Cyclosporine; Disease Progression; Glucocorticoids; Homeostasis; Humans; Immunologic Factors; Immunosuppressive Agents; Isoxazoles; Liver Cirrhosis, Biliary; Liver Transplantation; Peroxisome Proliferator-Activated Receptors; Receptors, Cytoplasmic and Nuclear; Rituximab; Treatment Outcome; United States; United States Food and Drug Administration; Ursodeoxycholic Acid

2020
Diagnosis and treatment of primary biliary cholangitis.
    United European gastroenterology journal, 2020, Volume: 8, Issue:6

    Topics: Autoantigens; Autoimmune Diseases; Bezafibrate; Biomarkers; Biopsy; Chenodeoxycholic Acid; Cholagogues and Choleretics; Disease Progression; Drug Therapy, Combination; Elasticity Imaging Techniques; End Stage Liver Disease; Fatigue; Female; Humans; Immunoglobulin M; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Liver Transplantation; Middle Aged; Off-Label Use; Prognosis; Pruritus; Quality of Life; Severity of Illness Index; Sjogren's Syndrome; Survival Rate; Treatment Outcome; Ursodeoxycholic Acid

2020
Safety of fibrates in cholestatic liver diseases.
    Liver international : official journal of the International Association for the Study of the Liver, 2021, Volume: 41, Issue:6

    Topics: Bezafibrate; Cholagogues and Choleretics; Fibric Acids; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2021
Fibrates for the treatment of pruritus in primary biliary cholangitis: a systematic review and meta-analysis.
    Annals of palliative medicine, 2021, Volume: 10, Issue:7

    Topics: Bezafibrate; Fibric Acids; Humans; Liver Cirrhosis, Biliary; Pruritus; Ursodeoxycholic Acid

2021
    MMW Fortschritte der Medizin, 2021, Volume: 163, Issue:17

    Topics: Bezafibrate; Humans; Pruritus; Ursodeoxycholic Acid

2021
Efficacy and Safety of Bezafibrate Alone or in Combination with Ursodeoxycholic Acid in Primary Biliary Cholangitis: Systematic Review and Meta-Analysis.
    Digestive diseases and sciences, 2023, Volume: 68, Issue:4

    Topics: Bezafibrate; Cholagogues and Choleretics; Drug Therapy, Combination; Humans; Liver Cirrhosis, Biliary; Quality of Life; Ursodeoxycholic Acid

2023
Treatment of Primary Biliary Cholangitis: First-Line and Second-Line Therapies.
    Clinics in liver disease, 2022, Volume: 26, Issue:4

    Topics: Autoimmune Diseases; Bezafibrate; Cholagogues and Choleretics; Cholangitis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2022

Trials

5 trial(s) available for bezafibrate and ursodeoxycholic acid

ArticleYear
Bezafibrate in the treatment of primary biliary cirrhosis: comparison with ursodeoxycholic acid.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:10

    Topics: Aged; Autoimmune Diseases; Bezafibrate; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Ursodeoxycholic Acid

2000
Bezafibrate treatment: a new medical approach for PBC patients?
    Journal of gastroenterology, 2003, Volume: 38, Issue:6

    Topics: Alkaline Phosphatase; Bezafibrate; Bile Acids and Salts; Cholagogues and Choleretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Male; Middle Aged; Time Factors; Ursodeoxycholic Acid

2003
Anticholestatic effects of bezafibrate in patients with primary biliary cirrhosis treated with ursodeoxycholic acid.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Bezafibrate; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholagogues and Choleretics; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Female; Humans; Lipids; Liver; Liver Cirrhosis, Biliary; Liver Neoplasms; Male; Middle Aged; PPAR alpha; Pregnane X Receptor; Receptors, Steroid; Treatment Failure; Treatment Outcome; Ursodeoxycholic Acid

2013
A prospective randomized controlled study of long-term combination therapy using ursodeoxycholic acid and bezafibrate in patients with primary biliary cirrhosis and dyslipidemia.
    The American journal of gastroenterology, 2015, Volume: 110, Issue:3

    Topics: Alkaline Phosphatase; Bezafibrate; Cholagogues and Choleretics; Creatinine; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Dyslipidemias; Female; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Male; Middle Aged; Myalgia; Prognosis; Renal Insufficiency; Survival Rate; Time; Treatment Outcome; Ursodeoxycholic Acid

2015
A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis.
    The New England journal of medicine, 2018, Jun-07, Volume: 378, Issue:23

    Topics: Adult; Bezafibrate; Bile Acids and Salts; Cholangitis; Double-Blind Method; Female; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Male; Middle Aged; Placebos; Treatment Failure; Ursodeoxycholic Acid

2018

Other Studies

40 other study(ies) available for bezafibrate and ursodeoxycholic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Combination therapy of bezafibrate and ursodeoxycholic acid in primary biliary cirrhosis: a preliminary study.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:1

    Topics: Aged; Alkaline Phosphatase; Bezafibrate; Cholagogues and Choleretics; Drug Therapy, Combination; gamma-Glutamyltransferase; Humans; Hypolipidemic Agents; Immunoglobulin M; Liver Cirrhosis, Biliary; Middle Aged; Pilot Projects; Ursodeoxycholic Acid

2000
Effect of bezafibrate in primary biliary cirrhosis: a pilot study.
    Liver, 2001, Volume: 21, Issue:3

    Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Bezafibrate; Female; gamma-Glutamyltransferase; Humans; Hypolipidemic Agents; Immunoglobulin M; Liver Cirrhosis, Biliary; Male; Middle Aged; Pilot Projects; Time Factors; Treatment Outcome; Ursodeoxycholic Acid

2001
[A case of primary sclerosing cholangitis presenting transient hypoperfusion and treated with bezafibrate beneficially].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2002, Volume: 99, Issue:2

    Topics: Alkaline Phosphatase; Bezafibrate; Bile Ducts; Biomarkers; Cholangitis, Sclerosing; Drug Therapy, Combination; Humans; Ischemia; Male; Middle Aged; Treatment Outcome; Ursodeoxycholic Acid

2002
New weapon for primary biliary cirrhosis from Japan.
    Journal of gastroenterology, 2003, Volume: 38, Issue:6

    Topics: Bezafibrate; Bile Acids and Salts; Drug Therapy, Combination; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2003
Comment on biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis.
    Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:1

    Topics: Alkaline Phosphatase; Bezafibrate; Cholagogues and Choleretics; Drug Synergism; Fenofibrate; Humans; Immunoglobulin M; Liver Cirrhosis, Biliary; Prognosis; Ursodeoxycholic Acid

2009
Additive improvement induced by bezafibrate in patients with primary biliary cirrhosis showing refractory response to ursodeoxycholic acid.
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:9

    Topics: Adult; Aged; Alkaline Phosphatase; Bezafibrate; Biomarkers; Drug Resistance; Drug Therapy, Combination; Female; Humans; Immunoglobulin M; Japan; Liver Cirrhosis, Biliary; Logistic Models; Male; Middle Aged; Prospective Studies; Time Factors; Treatment Failure; Ursodeoxycholic Acid

2011
Case of primary biliary cirrhosis-autoimmune hepatitis overlap which manifested after delivery.
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:12

    Topics: Adult; Bezafibrate; Cholagogues and Choleretics; Female; Hepatitis, Autoimmune; Humans; Liver Cirrhosis, Biliary; Postpartum Period; Pregnancy; Ursodeoxycholic Acid

2011
No more pilots, a phase III trial of fibrates in primary biliary cirrhosis is long overdue!
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:9

    Topics: Bezafibrate; Female; Humans; Liver Cirrhosis, Biliary; Male; Ursodeoxycholic Acid

2011
Fibrates as adjuvant therapy for chronic cholestatic liver disease: its time has come.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:5

    Topics: Anticholesteremic Agents; Bezafibrate; Cholagogues and Choleretics; Female; Humans; Liver Cirrhosis, Biliary; Male; Ursodeoxycholic Acid

2013
[Management of PBC cases failing to respond to UDCA].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2013, Volume: 110, Issue:1

    Topics: Bezafibrate; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2013
Bezafibrate normalizes alkaline phosphatase in primary biliary cirrhosis patients with incomplete response to ursodeoxycholic acid.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:2

    Topics: Alkaline Phosphatase; Bezafibrate; Elasticity Imaging Techniques; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Pilot Projects; Prospective Studies; Statistics, Nonparametric; Treatment Outcome; Ursodeoxycholic Acid

2014
Effectiveness of fenofibrate in comparison to bezafibrate for patients with asymptomatic primary biliary cirrhosis.
    Fukuoka igaku zasshi = Hukuoka acta medica, 2013, Volume: 104, Issue:10

    Topics: Adult; Aged; Asymptomatic Diseases; Bezafibrate; Cardiovascular Diseases; Cholesterol, LDL; Cohort Studies; Drug Therapy, Combination; Dyslipidemias; Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; PPAR alpha; Prognosis; Renal Insufficiency; Retrospective Studies; Risk Factors; Uric Acid; Ursodeoxycholic Acid

2013
Overlap of IgG4-related sclerosing cholangitis and primary biliary cirrhosis.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:13

    Topics: Bezafibrate; Cholagogues and Choleretics; Cholangitis, Sclerosing; Drug Therapy, Combination; Humans; Immunoglobulin G; Liver Cirrhosis, Biliary; Male; Middle Aged; Ursodeoxycholic Acid

2014
Biochemical responses to bezafibrate improve long-term outcome in asymptomatic patients with primary biliary cirrhosis refractory to UDCA.
    Journal of gastroenterology, 2015, Volume: 50, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Bezafibrate; Databases, Factual; Drug Therapy, Combination; Female; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid

2015
Combination Therapy of Ursodeoxycholic Acid and Bezafibrate in Patients With Primary Biliary Cirrhosis: The End of the Steroid Era in Autoimmune Liver Diseases?
    The American journal of gastroenterology, 2015, Volume: 110, Issue:7

    Topics: Bezafibrate; Dyslipidemias; Female; Humans; Liver Cirrhosis, Biliary; Male; Myalgia; Renal Insufficiency; Ursodeoxycholic Acid

2015
Response to Licinio et al.
    The American journal of gastroenterology, 2015, Volume: 110, Issue:7

    Topics: Bezafibrate; Dyslipidemias; Female; Humans; Liver Cirrhosis, Biliary; Male; Myalgia; Renal Insufficiency; Ursodeoxycholic Acid

2015
Identification of microRNA profiles associated with refractory primary biliary cirrhosis.
    Molecular medicine reports, 2016, Volume: 14, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents; Bezafibrate; Cholagogues and Choleretics; Drug Resistance; Female; Gene Expression Regulation; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Male; MicroRNAs; Middle Aged; Prednisolone; Transcriptome; Ursodeoxycholic Acid

2016
Effects of Bezafibrate on Outcome and Pruritus in Primary Biliary Cholangitis With Suboptimal Ursodeoxycholic Acid Response.
    The American journal of gastroenterology, 2018, Volume: 113, Issue:1

    Topics: Alkaline Phosphatase; Bezafibrate; Carcinoma, Hepatocellular; Cholagogues and Choleretics; Disease Progression; Drug Therapy, Combination; Elasticity Imaging Techniques; Female; Humans; Hypolipidemic Agents; Jaundice; Liver Cirrhosis, Biliary; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Prognosis; Pruritus; Ursodeoxycholic Acid; Visual Analog Scale

2018
Editorial: Itching to Know: Role of Fibrates in PBC.
    The American journal of gastroenterology, 2018, Volume: 113, Issue:1

    Topics: Bezafibrate; Cholangitis; Fibric Acids; Humans; Liver Cirrhosis, Biliary; Pruritus; Ursodeoxycholic Acid

2018
Primary sclerosing cholangitis response to the combination of fibrates with ursodeoxycholic acid: French-Spanish experience.
    Clinics and research in hepatology and gastroenterology, 2018, Volume: 42, Issue:6

    Topics: Adult; Aged; Alkaline Phosphatase; Bezafibrate; Cholagogues and Choleretics; Cholangitis, Sclerosing; Drug Therapy, Combination; Female; Fenofibrate; France; Humans; Hypolipidemic Agents; Liver Function Tests; Male; Middle Aged; Pruritus; Retrospective Studies; Spain; Ursodeoxycholic Acid; Young Adult

2018
Therapeutics Highlights from ILC 2018, the EASL annual congress.
    Clinics and research in hepatology and gastroenterology, 2018, Volume: 42, Issue:4

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antiviral Agents; Bezafibrate; Budesonide; CCR5 Receptor Antagonists; Congresses as Topic; Fibroblast Growth Factors; Gastrointestinal Agents; Humans; Imidazoles; Liver Diseases; Pyridazines; Sulfoxides; Uracil; Ursodeoxycholic Acid

2018
Bezafibrate in Primary Biliary Cholangitis.
    The New England journal of medicine, 2018, 09-06, Volume: 379, Issue:10

    Topics: Bezafibrate; Cholangitis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2018
In primary biliary cholangitis, adding bezafibrate to ursodeoxycholic acid increased complete biochemical response.
    Annals of internal medicine, 2018, 10-16, Volume: 169, Issue:8

    Topics: Bezafibrate; Cholangitis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2018
[Bezafibrate for primary biliary cholangitis : Bezafibrate in combination with ursodeoxycholic acid in primary biliary cholangitis (BEZURSO) trial].
    Der Internist, 2018, Volume: 59, Issue:12

    Topics: Bezafibrate; Cholangitis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2018
Letter: reduction in projected mortality or need for liver transplantation associated with bezafibrate add-on in primary biliary cholangitis with incomplete UDCA response.
    Alimentary pharmacology & therapeutics, 2019, Volume: 49, Issue:2

    Topics: Bezafibrate; Cholangitis; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Ursodeoxycholic Acid

2019
Bezafibrate Improves GLOBE and UK-PBC Scores and Long-Term Outcomes in Patients With Primary Biliary Cholangitis.
    Hepatology (Baltimore, Md.), 2019, Volume: 70, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bezafibrate; Cholangitis; Female; Humans; Male; Middle Aged; Propensity Score; Proportional Hazards Models; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid

2019
Additional fibrate treatment in UDCA-refractory PBC patients.
    Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:9

    Topics: Alkaline Phosphatase; Bezafibrate; Cholagogues and Choleretics; Drug Therapy, Combination; Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Proportional Hazards Models; Retrospective Studies; Ursodeoxycholic Acid

2019
IgM response is a prognostic biomarker of primary biliary cholangitis treated with ursodeoxycholic acid and bezafibrate.
    Journal of gastroenterology and hepatology, 2020, Volume: 35, Issue:4

    Topics: Bezafibrate; Biomarkers; Drug Therapy, Combination; Female; Humans; Immunoglobulin M; Liver Cirrhosis, Biliary; Male; Middle Aged; Prognosis; Retrospective Studies; Survival Rate; Time Factors; Treatment Outcome; Ursodeoxycholic Acid

2020
Switching vs. add-on strategy in PBC treatment: Lessons from UDCA and bezafibrate experience.
    Journal of hepatology, 2020, Volume: 72, Issue:6

    Topics: Bezafibrate; Cholagogues and Choleretics; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2020
Reply to: "Switching vs. add-on strategy in PBC treatment: Lessons from UDCA and bezafibrate experience".
    Journal of hepatology, 2020, Volume: 72, Issue:6

    Topics: Bezafibrate; Cholagogues and Choleretics; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2020
A validation study of the Ursodeoxycholic Acid Response Score in Japanese patients with primary biliary cholangitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2020, Volume: 40, Issue:8

    Topics: Aged; Alkaline Phosphatase; Bezafibrate; Cholagogues and Choleretics; Female; Humans; Japan; Liver Cirrhosis, Biliary; Male; Middle Aged; Ursodeoxycholic Acid

2020
Ursodeoxycholic acid and bezafibrate were useful for steroid-refractory, immune-related hepatitis: a case report.
    Journal of medical case reports, 2020, Nov-26, Volume: 14, Issue:1

    Topics: Aged; Bezafibrate; Humans; Male; Melanoma; Nivolumab; Skin Neoplasms; Ursodeoxycholic Acid

2020
Bezafibrate therapy in primary biliary cholangitis refractory to ursodeoxycholic acid: a longitudinal study of paired liver biopsies at 5 years of follow up.
    Alimentary pharmacology & therapeutics, 2021, Volume: 54, Issue:9

    Topics: Bezafibrate; Biopsy; Cholagogues and Choleretics; Drug Therapy, Combination; Follow-Up Studies; Humans; Liver Cirrhosis, Biliary; Longitudinal Studies; Ursodeoxycholic Acid

2021
Editorial: bezafibrate in the treatment of patients with primary biliary cholangitis-are we there yet? Authors' reply.
    Alimentary pharmacology & therapeutics, 2022, Volume: 55, Issue:2

    Topics: Bezafibrate; Cholangitis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2022
Editorial: bezafibrate in the treatment of patients with primary biliary cholangitis-are we there yet?
    Alimentary pharmacology & therapeutics, 2022, Volume: 55, Issue:2

    Topics: Bezafibrate; Cholangitis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2022
Ursodeoxycholic acid is associated with improved long-term outcome in patients with primary sclerosing cholangitis.
    Journal of gastroenterology, 2022, Volume: 57, Issue:11

    Topics: Bezafibrate; Cholagogues and Choleretics; Cholangitis, Sclerosing; Humans; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid

2022