bezafibrate has been researched along with troglitazone in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 14 (63.64) | 29.6817 |
| 2010's | 7 (31.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, PJ; Henke, BR; Sternbach, DD; Willson, TM | 1 |
| Andersen, AS; Brand, CL; Bury, PS; Fleckner, J; Jeppesen, L; Lehmann, SV; Mogensen, JP; Mortensen, SB; Panajotova, V; Pettersson, I; Polivka, Z; Rasmussen, HB; Sauerberg, P; Sindelar, K; Sturis, J; Svensson, LA; Wassermann, K; Wöldike, HF; Wulff, EM; Ynddal, L | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Kiem, PV; Kim, YH; Minh, CV; Ngan, NT; Quang, TH; Song, SB; Tai, BH; Thao, NP | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Anh, Hle T; Choi, CW; Kiem, PV; Kim, YH; Luyen, BT; Minh, CV; Ngan, NT; Nhiem, NX; Quang, TH; Tai, BH; Thao, NP; Yang, SY; Yen, PH | 1 |
| Harada, Y; Inoue, I; Ishii, J; Itabashi, A; Katayama, S; Negishi, K; Takahashi, K | 1 |
| Carmona, MC; Giralt, M; Iglesias, R; Mampel, T; Pedraza, N; Solanes, G; Vazquez, M; Villarroya, F; Viñas, O | 1 |
| Adzet, T; Alegret, M; Cabrero, A; Laguna, JC; Sánchez, RM; Vázquez, M | 1 |
| Kimura, H; Momose, Y; Moriyama, S; Odaka, H; Sakamoto, J; Sawada, H; Sugiyama, Y | 1 |
| Anchiraico, GJ; Belury, MA; Fischer, SM; Gimenez-Conti, I; Liu, KL; Maldve, RE; Muga, SJ; Nickel, KP; Thuillier, P | 1 |
| Giralt, M; Iglesias, R; Pedraza, N; Solanes, G; Vázquez, M; Villarroya, F | 1 |
| Hosokawa, M; Kohno, H; Murakami, A; Okumura, A; Takashima, S; Tanaka, T; Yoshitani, S | 1 |
| Ihara, H; Nagai, N; Nakajima, T; Suzuki, Y; Takada, A; Takada, Y; Taminato, T; Urano, T | 1 |
| Lewis, JD; Su, CG | 1 |
| Fujioka, Y; Iwasaki, T; Masai, M; Morimoto, S; Ohyanagi, M; Okumura, T; Tsuboi, S; Tsujino, T | 1 |
| Alegret, M; Cabrero, A; Carrera, MV; Cubero, M; Jové, M; Laguna, JC; Llaverías, G; Planavila, A; Sánchez, R | 1 |
| Narce, M; Poisson, JP | 1 |
| Kohno, H; Sugie, S; Suzuki, R; Tanaka, T | 1 |
1 review(s) available for bezafibrate and troglitazone
| Article | Year |
|---|---|
The PPARs: from orphan receptors to drug discovery.
Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligands; Models, Molecular; Neoplasms; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2000 |
21 other study(ies) available for bezafibrate and troglitazone
| Article | Year |
|---|---|
Novel tricyclic-alpha-alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity.
Topics: Animals; Blood Glucose; Carbazoles; Cholesterol; Cholesterol, Dietary; Crystallography, X-Ray; Drug Evaluation, Preclinical; Glucose Tolerance Test; Hypoglycemic Agents; Hypolipidemic Agents; Male; Mice; Models, Molecular; Nuclear Proteins; Phenylpropionates; Pioglitazone; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides | 2002 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Anti-inflammatory and PPAR transactivational effects of secondary metabolites from the roots of Asarum sieboldii.
Topics: Anti-Inflammatory Agents; Asarum; Cyclooxygenase 2; Dose-Response Relationship, Drug; Furans; Hep G2 Cells; Humans; Inflammation; Magnetic Resonance Spectroscopy; Mass Spectrometry; NF-kappa B; Nitric Oxide Synthase Type II; Phenols; Plant Roots; PPAR alpha; Republic of Korea; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Diarylheptanoid glycosides from Tacca plantaginea and their effects on NF-κB activation and PPAR transcriptional activity.
Topics: Antimetabolites; Diarylheptanoids; Dioscoreaceae; Enzyme Activation; Glycosides; Hep G2 Cells; Humans; Magnetic Resonance Spectroscopy; Methanol; Molecular Structure; NF-kappa B; Peroxisome Proliferator-Activated Receptors; Transcription, Genetic | 2012 |
Effect of troglitazone (CS-045) and bezafibrate on glucose tolerance, liver glycogen synthase activity, and beta-oxidation in fructose-fed rats.
Topics: Animals; Bezafibrate; Blood Glucose; Body Weight; Chromans; Diet; Drug Tolerance; Fatty Acids, Nonesterified; Fructose; Glucose; Glycogen Synthase; Hypoglycemic Agents; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Potassium Cyanide; Rats; Rats, Wistar; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 1995 |
Impaired expression of the uncoupling protein-3 gene in skeletal muscle during lactation: fibrates and troglitazone reverse lactation-induced downregulation of the uncoupling protein-3 gene.
Topics: Animals; Anticholesteremic Agents; Bezafibrate; Carrier Proteins; Chromans; Female; Gene Expression Regulation; Hypoglycemic Agents; Hypolipidemic Agents; Ion Channels; Lactation; Litter Size; Mice; Microbodies; Mitochondria, Muscle; Mitochondrial Proteins; Muscle, Skeletal; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone; Uncoupling Agents; Uncoupling Protein 3; Weaning | 2000 |
Down-regulation of uncoupling protein-3 and -2 by thiazolidinediones in C2C12 myotubes.
Topics: Acyl-CoA Dehydrogenase; Animals; Atorvastatin; Bezafibrate; Carnitine O-Palmitoyltransferase; Carrier Proteins; Cell Line; Cholesterol; Chromans; Down-Regulation; Fatty Acid Desaturases; Heptanoic Acids; Hypoglycemic Agents; Ion Channels; Ligands; Membrane Transport Proteins; Mice; Mitochondrial Proteins; Muscles; Oleic Acid; Peroxisome Proliferators; Proteins; Pyrimidines; Pyrroles; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Triazenes; Troglitazone; Uncoupling Protein 2; Uncoupling Protein 3 | 2000 |
Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone.
Topics: Animals; Apolipoprotein A-I; Bezafibrate; Chlorocebus aethiops; Chromans; COS Cells; Fenofibrate; Gene Expression Regulation; Humans; Hypoglycemic Agents; Kinetics; Pioglitazone; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Transfection; Troglitazone; Tumor Cells, Cultured | 2000 |
Activators of peroxisome proliferator-activated receptor-alpha partially inhibit mouse skin tumor promotion.
Topics: Animals; Anticarcinogenic Agents; Bezafibrate; Blotting, Western; Cell Differentiation; Cell Line; Chromans; Female; Keratinocytes; Linoleic Acid; Mice; Mice, Inbred SENCAR; Papilloma; Peroxisome Proliferators; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Skin; Skin Neoplasms; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Up-Regulation | 2000 |
Differential regulation of expression of genes encoding uncoupling proteins 2 and 3 in brown adipose tissue during lactation in mice.
Topics: Adipose Tissue, Brown; Animals; Bezafibrate; Carrier Proteins; Chromans; Dietary Fats; Female; Gene Expression Regulation; Ion Channels; Lactation; Litter Size; Membrane Transport Proteins; Mice; Mitochondrial Proteins; Pregnancy; Proteins; Pyrimidines; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone; Uncoupling Protein 2; Uncoupling Protein 3 | 2001 |
Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Bezafibrate; Cell Division; Chromans; Colitis; Colonic Neoplasms; Dextran Sulfate; Growth Substances; Intestinal Mucosa; Ligands; Male; Mucins; Muscle Proteins; Neuropeptides; Nucleolus Organizer Region; Peptides; Precancerous Conditions; Proteins; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Silver Staining; Thiazoles; Thiazolidinediones; Transcription Factors; Trefoil Factor-2; Trefoil Factor-3; Troglitazone | 2001 |
Bezafibrate attenuates the overexpression of plasminogen activator inhibitor-1 messenger RNA by a combination of mono-unsaturated fatty acid and insulin in hepG2 cells.
Topics: Bezafibrate; Blotting, Northern; Carcinoma, Hepatocellular; Chromans; Culture Media, Conditioned; Dose-Response Relationship, Drug; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Humans; Insulin; Liver Neoplasms; Oleic Acid; Plasminogen Activator Inhibitor 1; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Cells, Cultured; Up-Regulation | 2001 |
Antineoplastic and anti-inflammatory effects of PPAR ligands in colitis.
Topics: Animals; Antioxidants; Bezafibrate; Chromans; Colitis; Colon; DNA-Binding Proteins; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
Troglitazone reduces activity of the Na+/H+ exchanger in fructose-fed borderline hypertensive rats.
Topics: Animals; Bezafibrate; Blood Glucose; Blood Platelets; Blood Pressure; Calcium; Chromans; Diet; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Fructose; Hydrogen-Ion Concentration; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypolipidemic Agents; Insulin; Male; Propionates; Rats; Sodium-Hydrogen Exchangers; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Vasodilator Agents | 2003 |
Differential effects of peroxisome proliferator-activated receptor activators on the mRNA levels of genes involved in lipid metabolism in primary human monocyte-derived macrophages.
Topics: Bezafibrate; Cholesterol; Chromans; Fenofibrate; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Metabolism; Lipoproteins, LDL; Macrophages; Monocytes; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2003 |
Novel PPARgamma-dependent and independent effects for thiazolidinediones.
Topics: Animals; Bezafibrate; Body Weight; Chromans; Diabetes Mellitus, Type 2; Gene Expression; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Proteins; Mice; Monocytes; Pancreas; Pioglitazone; PPAR alpha; PPAR gamma; Pregnancy Proteins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Troglitazone; Tumor Necrosis Factor-alpha | 2003 |
Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Bezafibrate; Body Weight; Chromans; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Hypolipidemic Agents; Immunohistochemistry; Inflammation; Injections, Intraperitoneal; Ligands; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Organ Size; Peroxisome Proliferator-Activated Receptors; Sulfonamides; Temperature; Thiazolidinediones; Troglitazone; Tyrosine; Vasodilator Agents | 2005 |