Page last updated: 2024-08-23

bezafibrate and simvastatin

bezafibrate has been researched along with simvastatin in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19903 (5.17)18.7374
1990's29 (50.00)18.2507
2000's14 (24.14)29.6817
2010's12 (20.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Desager, JP; Harvengt, C; Horsmans, Y1
Bruckert, E; De Gennes, JL; Truffert, J1
Charleson, H; French, JK; Lewis, GR; Lintott, CJ; Maling, TJ; Nye, ER; Reuben, S; Scott, RS; Sharpe, DN; White, HD1
Bo, M; Bonino, F; Fabris, F; Gottero, M; Molaschi, M; Neirotti, M; Pernigotti, L1
Garcia, RC; Nakandakare, E; Oliveira, HC; Quintão, EC; Rocha, JC; Sperotto, G1
Shapiro, DR; Walker, JF1
Jankelow, D; Myburgh, DP; Neutel, JM; Smith, DH1
Carlson, LA1
Bojanovski, D; Bojanovski, M; Canzler, H; Jochim, A; Schulzeck, P1
Bard, JM; Devulder, B; Douste-Blazy, P; Fruchart, JC; Harvengt, C; Lecerf, JM; Leclerc, V1
Weisweiler, P1
Galiana, J; Marchán, E; Montés, I; Pato, S1
Duncan, A; Murphy, MJ; O'Reilly, DS; Packard, CJ; Vallance, BD1
Branchi, A; Fiorenza, AM; Rovellini, A; Sommariva, D1
Barbir, M; Hunt, BJ; Kehely, A; MacMahon, M; Prescott, RJ; Thompson, GR; Wray, R1
Banks, D; Feher, MD; Foxton, J; Lant, AF; Wray, R1
Alberti, KG; Dyer, RG; Laker, MF; Stewart, MW1
Hutchesson, AC; Jones, AF; Moran, A1
Cummings, MH; Watts, GF1
Devuyst, O; Goffin, E; Pirson, Y; van Ypersele de Strihou, C1
Chapman, BA; Hurrell, MA; Wilson, IR1
Barbir, M; Galloway, D; Hunt, BJ; Ilsley, C; Mitchell, A; Taylor, A; Yacoub, M1
Branchi, A; Fasoli, A; Gugliandolo, AG; Rovellini, A; Sommariva, D1
Irsigler, H; Klein, W; Lechleitner, M; Patsch, JR; Sailer, S1
Baigts, F; Bruckert, E; De Gennes, JL; Malbecq, W1
Coulter, DM1
Ichikawa, M; Matsuyama, K; Nakai, A; Nishikata, M; Uchida, T1
Jeck, T; Keller, U; Riesen, WF1
Kesäniemi, YA1
Adzet, T; Alegret, M; Díaz, C; Hernández, G; Laguna, JC; Sánchez, RM; Verd, JC1
Sinzinger, H1
Beggs, PW; Clark, DW; Coulter, DM; Williams, SM1
Gavish, D; Leibovitz, E; Rubinstein, A; Shapira, I1
Bisicchia, A; Di Salvo, MM; Ferlito, S; Gallina, M; Mugno, F1
Isles, CG; Paterson, JR1
Black, DM1
Vita, JA; Winniford, M; Yeung, AC1
Adachi, K; Azuma, C; Hayakawa, J; Ikegami, H; Kurachi, H; Matumoto, K; Morishige, K; Murata, Y; Nishio, Y; Node, K; Ohmichi, M; Tasaka, K1
Ishibashi, S1
Barberá, G; Chacón, P; Hernández, C; Lecube, A; Lima, J; Simó, R1
Fujisaki, K; Itoh, Y; Maiguma, T; Makino, K; Oishi, R; Sasaguri, T; Takahashi-Yanaga, F; Teshima, D1
Fisman, EZ; Motro, M; Tenenbaum, A1
Balice, M; Chironi, G; Del-Pino, M; Gariepy, J; Levenson, J; Simon, A1
Dellavalle, RP; Drake, AL; Freeman, SR; Graber, M; Heilig, LF; McNealy, K; Schilling, LM1
Anzivino, C; Bertolotti, M; Carulli, L; Carulli, N; Corna, F; Del Puppo, M; Gabbi, C; Kienle, MG; Loria, P; Pellegrini, E; Ricchi, M; Zambianchi, L1
de Vries, R; Dullaart, RP; Sluiter, WJ; van Tol, A; Voorbij, HA1
Ahnström, J; Dahlbäck, B; de Vries, R; Dikkeschei, BD; Dullaart, RP; Kappelle, PJ; Nielsen, LB; Sluiter, WJ; van Tol, A; Wolffenbuttel, BH1
Constantinides, A; de Vries, R; Dullaart, RP; Gautier, T; Lagrost, L; Tselepis, AD; van Leeuwen, JJ; van Pelt, LJ1
Dallinga-Thie, GM; de Vries, R; Dikkeschei, BD; Dullaart, RP; Sluiter, WJ; van Tol, A1
Annema, W; de Boer, JF; Dullaart, RP; Tietge, UJ; Triolo, M1
Briel, M; Ferreira-González, I; Jakob, T; Nordmann, AJ; Schandelmaier, S1
Bortoletto, MS; Petris, AJ; Souza, RK1
Liu, QZ; Shang, J; Wang, H; Wang, LL; Zhou, J1
Borges, IBP; Misse, RG; Shinjo, SK; Silva, MG1
Haußmann-Vopel, S; Lehmann, C; Pavlovic, D; Wegner, A1

Reviews

9 review(s) available for bezafibrate and simvastatin

ArticleYear
[Toxic myopathies related to the administration of hypolipidemic agents: are the drugs the only things responsible?].
    Revista clinica espanola, 1995, Volume: 195, Issue:9

    Topics: Adult; Aged; Bezafibrate; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hypolipidemic Agents; Lovastatin; Male; Muscular Diseases; Simvastatin

1995
Serum triglycerides and clinical benefit in lipid-lowering trials.
    The American journal of cardiology, 1998, Feb-26, Volume: 81, Issue:4A

    Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol, LDL; Clinical Trials as Topic; Coronary Artery Disease; Coronary Disease; Estrogen Replacement Therapy; Female; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Myocardial Infarction; Myocardial Ischemia; Postmenopause; Pravastatin; Risk Factors; Simvastatin; Triglycerides

1998
[Antilipemic agents and atherothrombosis. Effects of antilipemic agents on blood platelet function, coagulation and fibrinolysis].
    Deutsche medizinische Wochenschrift (1946), 1998, Sep-18, Volume: 123, Issue:38

    Topics: Anticholesteremic Agents; Antiporters; Arteriosclerosis; Bezafibrate; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Clinical Trials as Topic; Clofibric Acid; Fenofibrate; Fibrinolysis; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Niacin; Pravastatin; Risk Factors; Simvastatin; Thrombosis

1998
Identifying patients at risk for coronary heart disease: implications from trials of lipid-lowering drug therapy.
    QJM : monthly journal of the Association of Physicians, 2000, Volume: 93, Issue:9

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Dietary Supplements; Female; Fibrinolytic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Life Style; Male; Middle Aged; Niacin; Patient Selection; Ramipril; Randomized Controlled Trials as Topic; Risk Factors; Simvastatin; Triglycerides

2000
Statins in children: what do we know and what do we need to do?
    Current atherosclerosis reports, 2001, Volume: 3, Issue:1

    Topics: Atorvastatin; Bezafibrate; Child; Child Welfare; Cost-Benefit Analysis; Drug Approval; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Pyridines; Pyrroles; Simvastatin

2001
[Guideline for management of lipid metabolism].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 9

    Topics: Bezafibrate; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Evidence-Based Medicine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Practice Guidelines as Topic; Primary Prevention; Risk; Simvastatin

2002
Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.
    Journal of the National Cancer Institute, 2006, Nov-01, Volume: 98, Issue:21

    Topics: Atorvastatin; Bezafibrate; Clofibrate; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Incidence; Lovastatin; Melanoma; Odds Ratio; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Reproducibility of Results; Simvastatin; Skin Neoplasms; United States

2006
Fibrates for primary prevention of cardiovascular disease events.
    The Cochrane database of systematic reviews, 2016, 11-16, Volume: 11

    Topics: Atorvastatin; Bezafibrate; Cardiovascular Diseases; Clofibric Acid; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Middle Aged; Myocardial Infarction; Primary Prevention; Simvastatin; Stroke

2016
Lipid-lowering agent-triggered dermatomyositis and polymyositis: a case series and literature review.
    Rheumatology international, 2018, Volume: 38, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Bezafibrate; Dermatomyositis; Female; Glucocorticoids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Immunosuppressive Agents; Male; Middle Aged; Polymyositis; Remission Induction; Retrospective Studies; Risk Factors; Simvastatin; Time Factors; Treatment Outcome

2018

Trials

24 trial(s) available for bezafibrate and simvastatin

ArticleYear
Effects of combined bezafibrate-simvastatin appraised in healthy subjects.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:5

    Topics: Adult; Anticholesteremic Agents; Bezafibrate; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lipids; Lovastatin; Male; Muscles; Pain; Phosphatidylcholine-Sterol O-Acyltransferase; Simvastatin

1992
[Comparison about the efficacy and tolerability between simvastatin and bezafibrate in the treatment of hypercholesterolemia].
    Annales de medecine interne, 1991, Volume: 142, Issue:7

    Topics: Adult; Anticholesteremic Agents; Bezafibrate; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin

1991
Treatment of primary hypercholesterolaemia with simvastatin. New Zealand multicentre evaluation.
    The Medical journal of Australia, 1991, Oct-07, Volume: 155, Issue:7

    Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Cholesterol; Cholesterol, LDL; Cohort Studies; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; New Zealand; Simvastatin

1991
Hemorheologic and coagulative pattern in hypercholesterolemic subjects treated with lipid-lowering drugs.
    Angiology, 1991, Volume: 42, Issue:2

    Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Blood Coagulation; Blood Coagulation Factors; Cholesterol; Female; Hemostasis; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1991
Effects of simvastatin, bezafibrate and gemfibrozil on the quantity and composition of plasma lipoproteins.
    Atherosclerosis, 1990, Volume: 85, Issue:2-3

    Topics: Adult; Aged; Apolipoproteins; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl CoA Reductases; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin

1990
Hydroxymethylglutaryl coenzyme A reductase inhibitors as monotherapy in the treatment of hypercholesterolemia.
    The American journal of cardiology, 1990, Mar-20, Volume: 65, Issue:12

    Topics: Bezafibrate; Cholestyramine Resin; Double-Blind Method; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Probucol; Randomized Controlled Trials as Topic; Simvastatin

1990
Bezafibrate and simvastatin (MK-733) in the treatment of primary hypercholesterolaemia.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1990, May-19, Volume: 77, Issue:10

    Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1990
Comparison between simvastatin and bezafibrate in effect on plasma lipoproteins and apolipoproteins in primary hypercholesterolaemia.
    Lancet (London, England), 1988, Mar-19, Volume: 1, Issue:8586

    Topics: Adult; Aged; Apolipoproteins; Apolipoproteins B; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Lipoproteins, VLDL; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1988
Simvastatin and bezafibrate: effects on serum lipoproteins and lecithin: cholesterol acyltransferase activity in familial hypercholesterolaemia.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:6

    Topics: Adult; Anticholesteremic Agents; Bezafibrate; Double-Blind Method; Female; Humans; Hyperlipoproteinemia Type II; Lipoproteins; Lovastatin; Male; Middle Aged; Random Allocation; Simvastatin; Sterol O-Acyltransferase

1988
Effects of bezafibrate and of 2 HMG-CoA reductase inhibitors on lipoprotein (a) level in hypercholesterolemic patients.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Bezafibrate; Cholesterol; Delayed-Action Preparations; Diet; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipoprotein(a); Lovastatin; Male; Middle Aged; Pravastatin; Receptors, LDL; Simvastatin

1995
Combined bezafibrate and simvastatin treatment for mixed hyperlipidaemia.
    QJM : monthly journal of the Association of Physicians, 1995, Volume: 88, Issue:6

    Topics: Adolescent; Adult; Aged; Apolipoproteins; Bezafibrate; Cholesterol; Cholesterol, HDL; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hyperlipoproteinemia Type V; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Simvastatin; Treatment Outcome; Triglycerides

1995
The effects of lipid lowering drugs on metabolic control and lipoprotein composition in type 2 diabetic patients with mild hyperlipidaemia.
    Diabetic medicine : a journal of the British Diabetic Association, 1995, Volume: 12, Issue:3

    Topics: Apolipoproteins B; Bezafibrate; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Middle Aged; Phospholipids; Placebos; Pyrazines; Simvastatin; Triglycerides

1995
A randomized pilot trial of low-dose combination lipid-lowering therapy following coronary artery bypass grafting.
    Clinical cardiology, 1994, Volume: 17, Issue:2

    Topics: Analysis of Variance; Bezafibrate; Colestipol; Coronary Artery Bypass; Double-Blind Method; Drug Therapy, Combination; Factor VII; Factor VIII; Female; Fibrinogen; Fibrinolysis; Humans; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pilot Projects; Simvastatin

1994
[Effectiveness, tolerance and safety of simvastatin in comparison with bezafibrate in treatment of hypercholesterolemia].
    Wiener medizinische Wochenschrift (1946), 1995, Volume: 145, Issue:21

    Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Diet, Fat-Restricted; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1995
Comparison of the efficacy of simvastatin and standard fibrate therapy in the treatment of primary hypercholesterolemia and combined hyperlipidemia.
    Clinical cardiology, 1995, Volume: 18, Issue:11

    Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol, LDL; Clofibric Acid; Fatty Acids, Volatile; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1995
Comparison of bezafibrate and simvastatin in the treatment of dyslipidaemia in patients with NIDDM.
    Diabetic medicine : a journal of the British Diabetic Association, 1997, Volume: 14, Issue:7

    Topics: Aged; Apolipoproteins; Bezafibrate; Creatine Kinase; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Fibrinogen; Glycated Hemoglobin; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Patient Compliance; Simvastatin

1997
Bezafibrate and simvastatin combination therapy for diabetic dyslipidaemia: efficacy and safety.
    Journal of internal medicine, 2000, Volume: 247, Issue:5

    Topics: Aged; Bezafibrate; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Simvastatin; Time Factors; Treatment Outcome

2000
Effects of bezafibrate and simvastatin on plasma lipoproteins in hypercholesterolemia resistant to hormone replacement therapy.
    Maturitas, 2001, May-30, Volume: 38, Issue:3

    Topics: Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Female; Hormone Replacement Therapy; Humans; Hypercholesterolemia; Hypolipidemic Agents; Middle Aged; Postmenopause; Simvastatin; Treatment Outcome; Triglycerides

2001
Effects of hypolipidemic treatment on serum markers of vascular inflammation in dyslipidemic men.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:3

    Topics: Adult; Bezafibrate; Biomarkers; Chemokine CCL2; E-Selectin; Gemfibrozil; Humans; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Inflammation Mediators; Lovastatin; Male; Middle Aged; Simvastatin; Vascular Cell Adhesion Molecule-1

2003
Serum paraoxonase-I activity is unaffected by short-term administration of simvastatin, bezafibrate, and their combination in type 2 diabetes mellitus.
    European journal of clinical investigation, 2009, Volume: 39, Issue:3

    Topics: Aged; Anticholesteremic Agents; Aryldialkylphosphatase; Bezafibrate; Carboxylic Ester Hydrolases; Case-Control Studies; Cholesterol, HDL; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Combinations; Humans; Male; Middle Aged; Simvastatin; Statistics as Topic

2009
Plasma apolipoprotein M responses to statin and fibrate administration in type 2 diabetes mellitus.
    Atherosclerosis, 2010, Volume: 213, Issue:1

    Topics: Apolipoproteins; Apolipoproteins M; Bezafibrate; Blood Pressure; Cholesterol; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipocalins; Male; Middle Aged; Placebos; Simvastatin

2010
Simvastatin but not bezafibrate decreases plasma lipoprotein-associated phospholipase A₂ mass in type 2 diabetes mellitus: relevance of high sensitive C-reactive protein, lipoprotein profile and low-density lipoprotein (LDL) electronegativity.
    European journal of internal medicine, 2012, Volume: 23, Issue:7

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Bezafibrate; C-Reactive Protein; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Humans; Hypolipidemic Agents; Lipoproteins, LDL; Male; Middle Aged; Simvastatin; Triglycerides

2012
Statin and fibrate combination does not additionally lower plasma cholesteryl ester transfer in type 2 diabetes mellitus.
    Clinical laboratory, 2012, Volume: 58, Issue:11-12

    Topics: Adult; Bezafibrate; Case-Control Studies; Cholesterol Ester Transfer Proteins; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Placebos; Simvastatin

2012
Simvastatin and bezafibrate increase cholesterol efflux in men with type 2 diabetes.
    European journal of clinical investigation, 2014, Volume: 44, Issue:3

    Topics: Anti-Inflammatory Agents; Antioxidants; Bezafibrate; Cholesterol; Cholesterol, HDL; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; High-Density Lipoproteins, Pre-beta; Humans; Hypolipidemic Agents; Lipoproteins, LDL; Male; Middle Aged; Simvastatin

2014

Other Studies

25 other study(ies) available for bezafibrate and simvastatin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[A case of familial hypercholesterolemia with therapeutic difficulties].
    Lakartidningen, 1990, Mar-07, Volume: 87, Issue:10

    Topics: Adult; Bezafibrate; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Lovastatin; Male; Nicotinic Acids; Simvastatin

1990
[Type IIa dyslipoproteinemia. Effects of simvastatin and bezafibrate on atherogenic and non-atherogenic lipoprotein particles].
    Presse medicale (Paris, France : 1983), 1988, Dec-17, Volume: 17, Issue:45

    Topics: Bezafibrate; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Lovastatin; Simvastatin

1988
Iatrogenic profound hypoalphalipoproteinaemia: an unrecognised cause of very low HDL cholesterol.
    Postgraduate medical journal, 1995, Volume: 71, Issue:838

    Topics: Adult; Anticholesteremic Agents; Bezafibrate; Cholesterol, HDL; Drug Interactions; Female; Fenofibrate; Humans; Hypolipoproteinemias; Lovastatin; Male; Middle Aged; Probucol; Simvastatin

1995
Long-term safety of statin-fibrate combination treatment in the management of hypercholesterolaemia in patients with coronary artery disease.
    British heart journal, 1995, Volume: 74, Issue:1

    Topics: Adult; Aged; Aspartate Aminotransferases; Bezafibrate; Cohort Studies; Coronary Disease; Creatine Kinase; Drug Therapy, Combination; Female; Fenofibrate; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pravastatin; Retrospective Studies; Simvastatin

1995
Dual bezafibrate-simvastatin therapy for combined hyperlipidaemia.
    Journal of clinical pharmacy and therapeutics, 1994, Volume: 19, Issue:6

    Topics: Adult; Aged; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1994
Drug treatment of hypercholesterolaemia in a patient with Gilbert's syndrome.
    Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 4)

    Topics: Administration, Oral; Bezafibrate; Bilirubin; Colestipol; Gilbert Disease; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Liver; Liver Function Tests; Lovastatin; Male; Middle Aged; Pravastatin; Pyrazines; Simvastatin

1994
Hypercholesterolemia treatment in a renal transplant patient.
    Clinical nephrology, 1994, Volume: 41, Issue:5

    Topics: Anticholesteremic Agents; Bezafibrate; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Humans; Hypercholesterolemia; Kidney Transplantation; Lovastatin; Male; Middle Aged; Postoperative Complications; Simvastatin

1994
Variation in the estimation of gallbladder volume using the sum-of-cylinders method.
    Investigative radiology, 1994, Volume: 29, Issue:5

    Topics: Bezafibrate; Body Mass Index; Gallbladder; Gallbladder Emptying; Humans; Hypolipidemic Agents; Lovastatin; Middle Aged; Reproducibility of Results; Simvastatin; Ultrasonography

1994
Effect of three fibrate derivatives and of two HMG-CoA reductase inhibitors on plasma fibrinogen level in patients with primary hypercholesterolemia.
    Thrombosis and haemostasis, 1993, Aug-02, Volume: 70, Issue:2

    Topics: Adult; Aged; Bezafibrate; Cholesterol, Dietary; Combined Modality Therapy; Female; Fenofibrate; Fibrinogen; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin

1993
Reasons for stopping drugs are monitored in New Zealand.
    BMJ (Clinical research ed.), 1996, Sep-21, Volume: 313, Issue:7059

    Topics: Adverse Drug Reaction Reporting Systems; Bezafibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Lovastatin; New Zealand; Product Surveillance, Postmarketing; Simvastatin

1996
Enhanced myopathy following administration of hypolipidemic agents under urethane anesthesia.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:1

    Topics: Anesthesia; Animals; Bezafibrate; Calcium; Creatine Kinase; Hypolipidemic Agents; Lovastatin; Male; Muscular Diseases; Pravastatin; Rats; Rats, Wistar; Simvastatin; Urethane

1997
Effect of hypolipidemic drugs on key enzyme activities related to lipid metabolism in normolipidemic rabbits.
    European journal of pharmacology, 1998, Apr-24, Volume: 347, Issue:2-3

    Topics: Acyltransferases; Animals; Atorvastatin; Bezafibrate; Cholesterol; Diacylglycerol O-Acyltransferase; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Lipids; Liver; Male; Phospholipids; Pyrroles; Rabbits; Simvastatin; Triglycerides

1998
A comparison of the use, effectiveness and safety of bezafibrate, gemfibrozil and simvastatin in normal clinical practice using the New Zealand Intensive Medicines Monitoring Programme (IMMP).
    British journal of clinical pharmacology, 1999, Volume: 47, Issue:1

    Topics: Bezafibrate; Cohort Studies; Comorbidity; Diabetes Complications; Female; Gemfibrozil; Humans; Hypertension; Lipids; Male; Myocardial Ischemia; New Zealand; Practice Patterns, Physicians'; Product Surveillance, Postmarketing; Random Allocation; Retrospective Studies; Risk Factors; Simvastatin; Surveys and Questionnaires; Treatment Outcome

1999
Plasma levels of E-selectin in normolipemic and hyperlipemic arteriopathic patients after vasoactive and lipid-lowering treatment.
    Minerva cardioangiologica, 2000, Volume: 48, Issue:3

    Topics: Arterial Occlusive Diseases; Bezafibrate; E-Selectin; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Simvastatin; Vasoconstrictor Agents

2000
Coronary artery reactivity after treatment with simvastatin.
    Current atherosclerosis reports, 2001, Volume: 3, Issue:2

    Topics: Amlodipine; Bezafibrate; Coronary Angiography; Coronary Artery Disease; Coronary Disease; Coronary Vessels; Female; Humans; Male; Myocardial Infarction; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Simvastatin; Survival Rate; Treatment Outcome

2001
Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:3

    Topics: Bezafibrate; Clofibrate; Clofibric Acid; Disease Models, Animal; Drug Synergism; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma, Embryonal; RNA, Messenger; Simvastatin; Time Factors; Transcription Factors; Tumor Cells, Cultured

2003
Bezafibrate and simvastatin: different beneficial effects for different therapeutic aims.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:4

    Topics: Bezafibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Simvastatin

2004
Differential associations of statin and fibrate treatment with carotid arterial remodeling.
    American journal of hypertension, 2005, Volume: 18, Issue:11

    Topics: Adult; Atorvastatin; Bezafibrate; Body Mass Index; Carotid Arteries; Cholesterol, HDL; Clofibric Acid; Cohort Studies; Dyslipidemias; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fibric Acids; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Male; Middle Aged; Multivariate Analysis; Pravastatin; Pyridines; Pyrroles; Risk Factors; Simvastatin; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography

2005
Correlation between plasma levels of 7alpha-hydroxy-4-cholesten-3-one and cholesterol 7alpha-hydroxylation rates in vivo in hyperlipidemic patients.
    Steroids, 2008, Volume: 73, Issue:11

    Topics: Aged; Anticholesteremic Agents; Bezafibrate; Cholestenones; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholestyramine Resin; Complement C4; Data Interpretation, Statistical; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Kinetics; Male; Middle Aged; Reference Standards; Simvastatin

2008
[Public sector participation in the supply of dyslipidemia medication in a population-based study].
    Ciencia & saude coletiva, 2016, Volume: 21, Issue:12

    Topics: Adult; Aged; Bezafibrate; Brazil; Cardiovascular Diseases; Cross-Sectional Studies; Dyslipidemias; Female; Humans; Hypolipidemic Agents; Interviews as Topic; Male; Middle Aged; Prevalence; Public Sector; Simvastatin

2016
Simvastatin and Bezafibrate ameliorate Emotional disorder Induced by High fat diet in C57BL/6 mice.
    Scientific reports, 2017, 05-24, Volume: 7, Issue:1

    Topics: Animals; Behavior, Animal; Bezafibrate; Depression; Diet, High-Fat; Glucose Tolerance Test; Hindlimb Suspension; Hippocampus; Male; Mice; Serotonin; Signal Transduction; Simvastatin; Stress, Psychological; Swimming; Tryptophan

2017
Impact of lipid modulation on the intestinal microcirculation in experimental sepsis.
    Microvascular research, 2018, Volume: 120

    Topics: Animals; Anti-Inflammatory Agents; Bezafibrate; Blood Flow Velocity; Capillaries; Cytokines; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Intestines; Intravital Microscopy; Leukocyte Rolling; Lipid Metabolism; Lipopolysaccharides; Lipoproteins, HDL; Male; Microcirculation; Microscopy, Fluorescence; Microscopy, Video; Rats, Inbred Lew; Regional Blood Flow; Sepsis; Simvastatin

2018