Page last updated: 2024-08-23

bezafibrate and probucol

bezafibrate has been researched along with probucol in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19906 (24.00)18.7374
1990's12 (48.00)18.2507
2000's2 (8.00)29.6817
2010's5 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Cramb, R; Florkowski, CM1
Kłosiewicz-Latoszek, L; Szostak, WB1
Clerc, C; Cloarec, L; Doualin, G; Fertil, V; Legras, B; Ruelland, A1
Shapiro, DR; Walker, JF1
Saito, Y; Yoshida, S1
González, G; Páez Moreno, JP1
Kurasawa, T; Yamamoto, A; Yokoyama, S1
Balabanski, L; Goranov, I; Kerekovska, M; Naumova, R1
Harvengt, C; Heller, F1
Mordasini, R; Oster, P; Riesen, W; Riva, G1
Duncan, A; Murphy, MJ; O'Reilly, DS; Packard, CJ; Vallance, BD1
Arakawa, K; Bai, H; Hirata, K; Jimi, S; Liu, R; Saku, K; Sasaki, N; Zhang, B1
Shand, JH; West, DW1
Hirakoso, K; Kohno, T; Mori, T; Ohtani, A; Takashima, K; Takeyama, S1
Kanaki, T; Saito, Y1
Arakawa, K; Jimi, S; Liao, YL; Ohta, T; Ou, J; Saku, K; Zhang, B1
Miyake, Y; Toyota, Y; Yamamoto, A; Yamamura, T1
Bujo, H; Kobayashi, J; Matsunaga, A; Mori, S; Murano, S; Saito, Y; Sasaki, J; Takahashi, K; Yokote, K1
Matsuzawa, Y; Nagai, Y; Takemura, K; Yamashita, S; Yanagi, K1
Furuyama, M; Hashimoto, T; Hayasaka, K; Matsunaga, A; Ogino, D; Toyoda, K1

Reviews

3 review(s) available for bezafibrate and probucol

ArticleYear
Approaches to the management of hypercholesterolaemia.
    Journal of clinical pharmacy and therapeutics, 1992, Volume: 17, Issue:2

    Topics: Bezafibrate; Bile Acids and Salts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Niacin; Probucol

1992
[Anti-atherogenic drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:10

    Topics: Acute Disease; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Bezafibrate; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Probucol; Recurrence; Syndrome

1998
[Treatment of high blood cholesterol in patients with coronary heart disease].
    Nihon rinsho. Japanese journal of clinical medicine, 1994, Volume: 52 Suppl, Issue:Pt 1

    Topics: Anion Exchange Resins; Bezafibrate; Clinical Trials as Topic; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Niacin; Probucol; Risk Factors

1994

Trials

4 trial(s) available for bezafibrate and probucol

ArticleYear
Hydroxymethylglutaryl coenzyme A reductase inhibitors as monotherapy in the treatment of hypercholesterolemia.
    The American journal of cardiology, 1990, Mar-20, Volume: 65, Issue:12

    Topics: Bezafibrate; Cholestyramine Resin; Double-Blind Method; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Probucol; Randomized Controlled Trials as Topic; Simvastatin

1990
Comparative study of bezafibrate and probucol in hyperlipidaemia.
    Current medical research and opinion, 1989, Volume: 11, Issue:8

    Topics: Adult; Aged; Bezafibrate; Clinical Trials as Topic; Dietary Fats; Female; Humans; Hyperlipidemias; Male; Middle Aged; Phenols; Probucol

1989
[Behavior of high-density lipoproteins in drug lipid-lowering treatment].
    Schweizerische medizinische Wochenschrift, 1982, Jan-16, Volume: 112, Issue:3

    Topics: Adult; Apoproteins; Bezafibrate; Cholesterol; Cholesterol, HDL; Clofibric Acid; Colestipol; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lipoproteins, HDL; Male; Middle Aged; Probucol

1982
High-density lipoprotein and apolipoprotein A-I deficiency induced by combination therapy with probucol and bezafibrate.
    European journal of clinical pharmacology, 1995, Volume: 48, Issue:3-4

    Topics: Adult; Aged; Apolipoproteins; Bezafibrate; Drug Combinations; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins, HDL; Male; Middle Aged; Probucol; Time Factors

1995

Other Studies

18 other study(ies) available for bezafibrate and probucol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Comparative studies on the influence of different fibrates on serum lipoproteins in endogenous hyperlipoproteinaemia.
    European journal of clinical pharmacology, 1991, Volume: 40, Issue:1

    Topics: Adult; Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Colestipol; Female; Fenofibrate; Gemfibrozil; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged; Probucol

1991
Transitory deficit in high-density lipoproteins and apolipoprotein A-I.
    Clinical chemistry, 1990, Volume: 36, Issue:3

    Topics: Apolipoprotein A-I; Apolipoproteins A; Bezafibrate; Clofibric Acid; Drug Therapy, Combination; Fibric Acids; Humans; Hypolipidemic Agents; Lipoproteins, HDL; Male; Middle Aged; Probucol

1990
[Recent trend in the research of hyperlipidemia in Japan. Treatment of refractory hyperlipidemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1989, Volume: 78, Issue:10

    Topics: Anticholesteremic Agents; Bezafibrate; Blood Component Removal; Cholesterol; Drug Therapy, Combination; Heptanoic Acids; Humans; Hyperlipoproteinemia Type I; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type V; Hyperlipoproteinemias; Naphthalenes; Pravastatin; Probucol; Triglycerides

1989
A little more information about aggravation of probucol-induced HDL-reduction by clofibrate.
    Atherosclerosis, 1988, Volume: 70, Issue:1-2

    Topics: Adult; Aged; Bezafibrate; Cholesterol, HDL; Clofibrate; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lipoproteins, HDL; Male; Middle Aged; Phenols; Probucol

1988
[Indications for and the therapeutic action of hypolipidemic agents in patients with hyperlipoproteinemias].
    Vutreshni bolesti, 1987, Volume: 26, Issue:1

    Topics: Bezafibrate; Cholesterol; Drug Evaluation; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Nicotinyl Alcohol; Probucol; Triglycerides

1987
Effects of clofibrate, bezafibrate, fenofibrate and probucol on plasma lipolytic enzymes in normolipaemic subjects.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:1

    Topics: Adult; Bezafibrate; Cholesterol; Clofibrate; Fenofibrate; Humans; Hypolipidemic Agents; Lipase; Lipolysis; Lipoprotein Lipase; Male; Phosphatidylcholine-Sterol O-Acyltransferase; Probucol; Triglycerides

1983
Iatrogenic profound hypoalphalipoproteinaemia: an unrecognised cause of very low HDL cholesterol.
    Postgraduate medical journal, 1995, Volume: 71, Issue:838

    Topics: Adult; Anticholesteremic Agents; Bezafibrate; Cholesterol, HDL; Drug Interactions; Female; Fenofibrate; Humans; Hypolipoproteinemias; Lovastatin; Male; Middle Aged; Probucol; Simvastatin

1995
Inhibition of neutral cholesterol ester hydrolase in rat liver by fibric acids and probucol in vitro.
    Biochemical Society transactions, 1994, Volume: 22, Issue:4

    Topics: Animals; Bezafibrate; Clofibrate; Cytosol; Kinetics; Liver; Male; Microsomes, Liver; Probucol; Rats; Sterol Esterase

1994
The hypocholesterolemic action of TA-7552 and its effects on cholesterol metabolism in the rat.
    Atherosclerosis, 1994, Volume: 107, Issue:2

    Topics: Animals; Bezafibrate; Bile Acids and Salts; Cholestanol; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholestyramine Resin; Chromatography, Gas; Feces; Liver; Naphthols; Probucol; Rats; Rats, Sprague-Dawley

1994
Combined effects of probucol and benzafibrate on lipoprotein metabolism and liver cholesteryl ester transfer protein mRNA in cholesterol-fed rabbits.
    Japanese circulation journal, 1999, Volume: 63, Issue:6

    Topics: Animals; Anticholesteremic Agents; Base Sequence; Bezafibrate; Blotting, Northern; Carrier Proteins; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Cholesterol, HDL; Chromatography, High Pressure Liquid; Glycoproteins; Hypolipidemic Agents; Lipids; Lipoproteins; Liver; Male; Molecular Sequence Data; Probucol; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

1999
Low density lipoprotein (LDL) binding affinity for the LDL receptor in hyperlipoproteinemia.
    Atherosclerosis, 1999, Nov-01, Volume: 147, Issue:1

    Topics: Adult; Bezafibrate; Female; Humans; Hyperlipoproteinemias; Hypertriglyceridemia; Hypolipidemic Agents; Lipids; Lipoproteins, LDL; Male; Middle Aged; Particle Size; Probucol; Receptors, LDL

1999
Marked decrease in plasma apolipoprotein A-I and high density lipoprotein-cholesterol in a case with Werner syndrome.
    Clinica chimica acta; international journal of clinical chemistry, 2000, Volume: 293, Issue:1-2

    Topics: Adult; Anticholesteremic Agents; Apolipoprotein A-I; Bezafibrate; Cholesterol, HDL; Humans; Hypolipidemic Agents; Lipoproteins, HDL; Male; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Pravastatin; Probucol; Time Factors; Triglycerides; Werner Syndrome

2000
Improvement of nephrotic syndrome by intensive lipid-lowering therapy in a patient with lipoprotein glomerulopathy.
    Clinical and experimental nephrology, 2009, Volume: 13, Issue:6

    Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Apolipoproteins E; Bezafibrate; Child; Child, Preschool; Enalapril; Female; Hematuria; Humans; Hypolipidemic Agents; Kidney Diseases; Kidney Failure, Chronic; Kidney Glomerulus; Nephrotic Syndrome; Probucol; Tetrazoles; Valine; Valsartan

2009