bezafibrate has been researched along with clofibric acid in 131 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 65 (49.62) | 18.7374 |
1990's | 32 (24.43) | 18.2507 |
2000's | 26 (19.85) | 29.6817 |
2010's | 8 (6.11) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Abraham, DJ; Kennedy, PE; Mehanna, AS; Patwa, DC; Williams, FL | 1 |
Brown, PJ; Chapman, JM; Kliewer, SA; Koble, CS; Lehmann, JM; Lewis, MC; Moore, LB; Plunket, KD; Sundseth, SS; Willson, TM; Wilson, JG; Winegar, DA; Wu, Z | 1 |
Beneton, V; Boullay, AB; Boyer, T; Brewster, AG; Donche, F; Forest, MC; Fouchet, MH; Gellibert, FJ; Grillot, DA; Lambert, MH; Laroze, A; Le Grumelec, C; Linget, JM; Montana, VG; Nguyen, VL; Nicodème, E; Patel, V; Penfornis, A; Pianetti, PM; Pineau, O; Pohin, D; Potvain, F; Poulain, G; Ruault, CB; Saunders, M; Sierra, ML; Toum, J; Xu, HE; Xu, RX | 1 |
Maillet, EL; Margolskee, RF; Mosinger, B | 1 |
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
Bolzano, K; Krempler, F; Schellenberg, B; Schlierf, G | 1 |
Amiconi, G; Ascenzi, P; Bertollini, A; Coletta, M; Desideri, A; Polizio, F; Santucci, R | 1 |
Adzet, T; Alegret, M; Laguna, JC; Merlos, M; Sánchez, RM | 1 |
Adzet, T; Alegret, M; Laguna, JC; Merlos, M; Sánchez, R | 1 |
Cannon, JR; Eacho, PI | 1 |
Eacho, PI; Foxworthy, PS; Hoover, DM; White, SL | 1 |
Frishman, WH; Kahn, S; Zimetbaum, P | 1 |
Kłosiewicz-Latoszek, L; Szostak, WB | 1 |
Clerc, C; Cloarec, L; Doualin, G; Fertil, V; Legras, B; Ruelland, A | 1 |
Bonner, FW; Gibson, GG; Makowska, JM | 1 |
Angelin, B; Einarsson, K; Ståhlberg, D | 1 |
Bonner, FW; Eason, CT; Henry, G; Pattison, A; Powles, P; Spencer, AJ | 1 |
Agius, L; Alberti, KG; Gerondaes, P | 2 |
Krause, BR; Newton, RS | 1 |
Bonner, FW; Eason, CT; Howells, DD; Pattison, A; Spencer, AJ | 1 |
Palmer, RH | 1 |
Hunninghake, DB; Peters, JR | 1 |
Eacho, PI; Foxworthy, PS | 1 |
Boag, DE; Lorimer, AR; Packard, CJ; Shepherd, J; Stewart, JM | 1 |
Honková, M; Kunesová, M; Mares, P; Skorepa, J; Zeman, M | 1 |
Franceschini, G; Paoletti, R; Sirtori, CR | 1 |
Rüth, E; Vollmar, J | 1 |
Fischer, H; Oster, P; Roche, A; Schellenberg, B; Schlierf, G; Stiehl, A; Vollmar, J | 1 |
Canzler, H | 1 |
Keller, M; Lang, PD; Middelhoff, G; Mordasini, R; Oster, P; Riesen, W | 1 |
Holler, HD; Janka, HU; Mehnert, H; Standl, A | 1 |
Dorda, W; Kostner, GM; Mühlhauser, I; Prager, R; Schernthaner, G; Zechner, R | 1 |
Lang, PD; Vollmar, J | 1 |
Day, AJ; Hudson, K; Mojumder, S | 1 |
Kurlat, MI; Neuman, J; Neuman, MP | 1 |
Djaja, S; Machalke, K; Richter, E | 1 |
Fahimi, HD; Hartig, F; Ozel, M; Reinicke, A; Stegmeier, K; Sujatta, M; Yokota, S | 1 |
Lageder, H | 1 |
Abshagen, U; Marinow, J; Spörl-Radun, S | 1 |
Boberg, J; Gustafsson, IB; Hellsing, K; Ledermann, H; Lithell, H; Ostlund-Lindqvist, AM; Vessby, B | 1 |
Kokot, F; Szczechowska, E | 1 |
Dick, TB; Ledermann, HM; Marples, J; Whittington, J | 1 |
Grützmacher, P; Lang, W; Scheuermann, E | 1 |
Mordasini, R; Oster, P; Riesen, W; Riva, G | 1 |
Day, AJ; Hudson, K; Marceglia, A | 1 |
Bode, G; Ditschuneit, H; Hutt, V; Klör, HU; Wechsler, JG | 1 |
Drosner, M; Janetschek, P; Schwandt, P; Weisweiler, P | 1 |
Lazarow, PB; Leroy-Houyet, MA; Shio, H | 1 |
Lang, PD; Mertz, DP; Vollmar, J | 1 |
Lehmann-Leo, W; Luley, C; Scheffler, W; Schilling, A; Schwartzkopff, W; Wegscheider, K | 1 |
Stratmann, FW | 1 |
Ledermann, H; Lithell, H; Vessby, B | 1 |
Heidland, A; Hörl, M; Hörl, WH | 1 |
Anderson, P; Norbeck, HE | 2 |
Fringes, B; Riede, UN; von Deimling, O | 1 |
Day, AJ; Hudson, K | 1 |
Braeuning, C; Middelhoff, G; Schlierf, G; Wirth, A | 1 |
Kłosiewicz-Latoszek, L; Naruszewicz, M; Nowicka, G; Szostak, WB | 1 |
Hofmann, H; Holler, HD; Stratmann, FW | 1 |
Bertuletti, R; Carini, M; Maffei, FR; Tofanetti, O | 1 |
Schwandt, P; Weisweiler, P | 1 |
Ditschuneit, H; Hutt, V; Klör, HU; Wechsler, JG | 2 |
Hausmann, L; Kaffarnik, H; Mühlfellner, G; Mühlfellner, O; Schneider, J; Schubotz, R | 1 |
Seidel, D; Walli, AK | 1 |
Bock, KD; Heidemann, H | 1 |
Kjellin, KG; Ledermann, H; Noring, L | 1 |
Bruneder, H; Klein, HJ | 1 |
Bock, KD | 1 |
Fährenkemper, T; Foerster, EC; Graf, P; Rabe, U; Sies, H | 1 |
Kaufmann, B; Ledermann, H | 1 |
Carini, M; Facino, RM | 1 |
Abshagen, U; Kaufmann, B; Kösters, W; Lang, PD | 1 |
Bachmann, C; Fragiacomo, C; Noseda, G; Weidmann, P | 1 |
Calder, D; Luley, C; Scheffler, W; Schilling, A; Schwartzkopff, W | 1 |
Mertz, DP | 1 |
Schonfeld, G | 1 |
Dujovne, CA; Lozada, A | 1 |
Capps, NE | 1 |
Devuyst, O; Goffin, E; Pirson, Y; van Ypersele de Strihou, C | 2 |
Adzet, T; Alegret, M; Laguna, JC; Merlos, M; Sánchez, RM; Vázquez, M; Viñals, M | 2 |
Shepherd, J | 1 |
Armitage, M; McLeod, AJ; Warren, RJ | 1 |
Baigts, F; Bruckert, E; De Gennes, JL; Malbecq, W | 1 |
Accatino, L; Amigo, L; Andrade, L; Chianale, J; Gonzalez, S; Nervi, F; Pizarro, M; Rigotti, A; Vollrath, V; Wielandt, AM | 1 |
Galloway, SM; Johnson, TE; Ledwith, BJ; Manam, S; Nichols, WW; Pauley, CJ; Wagner, LK | 1 |
Nishimaki-Mogami, T; Okochi, E; Suzuki, K; Takahashi, A | 1 |
Nishimaki-Mogami, T; Suzuki, K; Takahashi, A | 1 |
Betteridge, DJ; O'Bryan-Tear, CG | 1 |
Cuniberti, LA; Masnatta, LD; Rey, RH; Werba, JP | 1 |
de Wit, EC; Huisman, H; Kaptein, A; Neele, DM; Princen, HM | 1 |
Sinzinger, H | 1 |
Wallace, KB; Zhou, S | 1 |
Eriksson, P; Hamsten, A; Nilsson, L; Takemura, T | 1 |
Ganotakis, ES; Jagroop, IA; Mikhailidis, DP; Papadakis, JA; Winder, AF | 1 |
Bottoni, P; Ficarra, S; Giardina, B; Nocca, G; Puggioni, P; Remiddi, F; Rumi, C; Scatena, R; Sole, PD | 1 |
Madden, BP; Millner, R; Parker, J; Rolfe, LM; Seymour, CA; Sharobeem, KM | 1 |
Cabrero, A; Ciudad, CJ; Laguna, JC; Noé, V; Rodríguez, C | 1 |
Abramowicz, D; Antoine, M; Broeders, N; Knoop, C; Tielemans, C | 1 |
Adzet, T; Cabrero, A; Ciudad, CJ; Laguna, JC; Rodríguez, C; Roglans, N; Sánchez, RM; Vázquez, M | 1 |
Doolman, R; Gavendo, S; Harats, D; Marko, D; Sela, BA; Shaish, A; Yodfat, O | 1 |
Bargman, JM; Lipscombe, J | 1 |
Athyros, V; Bairaktari, E; Elisaf, M; Ganotakis, E; Rizos, E; Seferiades, C; Tsimihodimos, V | 1 |
Gervois, PP; Kleemann, R; Kooistra, T; Princen, HM; Staels, B; Verschuren, L | 1 |
Fujisaki, K; Itoh, Y; Maiguma, T; Makino, K; Oishi, R; Sasaguri, T; Takahashi-Yanaga, F; Teshima, D | 1 |
Baldwin, GS; Ford, J; Lachal, S; Shulkes, A | 1 |
Bottoni, P; De Sole, P; Ferrari, F; Giardina, B; Martorana, GE; Rossi, C; Scatena, R | 1 |
Aguilar, C; Borrull, F; Calull, M; Macià, A | 1 |
Balice, M; Chironi, G; Del-Pino, M; Gariepy, J; Levenson, J; Simon, A | 1 |
Elisaf, MS; Mikhailidis, DP; Milionis, HJ | 1 |
Hauzer, A; Komsta, Ł; Majchrzak, E; Misztal, G | 1 |
Duriez, P; Fruchart, JC | 1 |
Boverhof, R; Jonkers, IJ; Kuipers, F; Masclee, AA; Princen, HM; Romijn, JA; Smelt, AH; Stellaard, F | 1 |
Battler, A; Behar, S; Benderly, M; Boyko, V; Goldbourt, U; Goldenberg, I; Haim, M; Tanne, D | 1 |
Berneis, K; Rizzo, M | 1 |
Nagao, M; Oikawa, S | 1 |
Caminada, D; Fent, K; Galicia, H; Weston, A | 1 |
Abadie, C; Alvergnas, M; Blanchard, N; Gallemann, D; Heyd, B; Mantion, G; Martin, H; Richert, L | 1 |
Abourbih, S; Eisenberg, MJ; Filion, KB; Genest, J; Joseph, L; Pilote, L; Poirier, P; Rinfret, S; Schiffrin, EL | 1 |
Davidson, MH | 1 |
Kawashima, Y; Kudo, N; Mitsumoto, A; Okada, H; Sakamoto, T; Sunaga, K; Tsuda, T; Yamazaki, T | 1 |
Ikeda, E; Kawashima, Y; Kudo, N; Mitsumoto, A; Sakamoto, T; Tanaka, S; Wakabayashi, M; Yamazaki, T | 1 |
Kunkel, U; Radke, M; Riml, J; Wörman, A | 1 |
Hoshina, M; Karahashi, M; Kawashima, Y; Kudo, N; Mitsumoto, A; Sakamoto, T; Yamazaki, T | 1 |
Fukuhara, H; Hoshina, M; Karahashi, M; Kawashima, Y; Kudo, N; Mitsumoto, A; Sakamoto, T; Yamazaki, T | 1 |
Briel, M; Ferreira-González, I; Jakob, T; Nordmann, AJ; Schandelmaier, S | 1 |
Fang, J; Guo, K; Hou, S; Hua, Z; Kong, X; Li, X; Ren, Z; Wu, Z | 1 |
13 review(s) available for bezafibrate and clofibric acid
Article | Year |
---|---|
Effects of gemfibrozil and other fibric acid derivatives on blood lipids and lipoproteins.
Topics: Bezafibrate; Cholesterol, HDL; Clofibric Acid; Diabetes Mellitus, Type 2; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Kidney Diseases; Lipoproteins, VLDL; Metabolic Clearance Rate; Triglycerides | 1991 |
Effects of fibric acid derivatives on biliary lipid composition.
Topics: Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Fenofibrate; Fibric Acids; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Male; Propionates; Random Allocation | 1987 |
Effect of fibric acid derivatives on blood lipid and lipoprotein levels.
Topics: Anticholesteremic Agents; Bezafibrate; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Pentanoic Acids | 1987 |
The effects of fibrates on lipoprotein and hemostatic coronary risk factors.
Topics: Arteriosclerosis; Bezafibrate; Blood Coagulation; Clofibric Acid; Coronary Disease; Fenofibrate; Fibric Acids; Gemfibrozil; Hemostasis; Humans; Hypolipidemic Agents; Lipoproteins; Risk Factors | 1994 |
Drug interactions with fibric acids.
Topics: Anticoagulants; Bezafibrate; Clofibrate; Clofibric Acid; Contraceptives, Oral; Coronary Disease; Drug Interactions; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Lipids | 1994 |
Mechanism of action of fibrates.
Topics: Apolipoproteins B; Bezafibrate; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Lipoproteins, LDL; Male; Receptors, LDL | 1993 |
[Antilipemic agents and atherothrombosis. Effects of antilipemic agents on blood platelet function, coagulation and fibrinolysis].
Topics: Anticholesteremic Agents; Antiporters; Arteriosclerosis; Bezafibrate; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Clinical Trials as Topic; Clofibric Acid; Fenofibrate; Fibrinolysis; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Niacin; Pravastatin; Risk Factors; Simvastatin; Thrombosis | 1998 |
Treatment of dyslipidaemias in patients with established vascular disease: a revival of the fibrates.
Topics: Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Myocardial Ischemia; Randomized Controlled Trials as Topic; Triglycerides | 2000 |
Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism.
Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Bezafibrate; Biological Transport; Cholesterol, HDL; Clofibric Acid; Coronary Artery Disease; Fenofibrate; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Liver; PPAR alpha; Randomized Controlled Trials as Topic; Triglycerides | 2006 |
The clinical significance of the size of low-density-lipoproteins and the modulation of subclasses by fibrates.
Topics: Bezafibrate; Clofibric Acid; Dyslipidemias; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins, LDL; Particle Size; Treatment Outcome | 2007 |
[Intervention for hypertriglyceridemia].
Topics: Aged; Bezafibrate; Clofibric Acid; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Female; Humans; Hypertriglyceridemia; Male; Middle Aged; Niacin | 2007 |
Effect of fibrates on lipid profiles and cardiovascular outcomes: a systematic review.
Topics: Anticholesteremic Agents; Bezafibrate; Cardiovascular Diseases; Cholesterol, LDL; Clofibric Acid; Female; Fenofibrate; Gemfibrozil; Humans; Hyperlipidemias; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Treatment Outcome | 2009 |
Fibrates for primary prevention of cardiovascular disease events.
Topics: Atorvastatin; Bezafibrate; Cardiovascular Diseases; Clofibric Acid; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Middle Aged; Myocardial Infarction; Primary Prevention; Simvastatin; Stroke | 2016 |
21 trial(s) available for bezafibrate and clofibric acid
Article | Year |
---|---|
Effects of fibric acid derivatives on biliary lipid composition.
Topics: Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Fenofibrate; Fibric Acids; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Male; Propionates; Random Allocation | 1987 |
[Therapeutic effects of bezafibrate in hyperlipidemia].
Topics: Adult; Aged; Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged | 1983 |
Influence of bezafibrate, fenofibrate, nicotinic acid and etofibrate on plasma high-density lipoprotein levels.
Topics: Adipose Tissue; Animals; Apolipoprotein C-II; Apolipoprotein C-III; Apolipoproteins; Apolipoproteins C; Bezafibrate; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Clofibric Acid; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Lipolysis; Lipoproteins, HDL; Niacin; Rats; Structure-Activity Relationship | 1983 |
[The effect of bezafibrate on biliary lipids (author's transl)].
Topics: Adult; Bezafibrate; Bile; Clofibrate; Clofibric Acid; Drug Evaluation; Humans; Hyperlipoproteinemias; Lipids | 1980 |
[Carbohydrate metabolism in bezafibrate therapy. Controlled study of glibenclamide-treated diabetics with hyperlipidemia].
Topics: Aged; Bezafibrate; Carbohydrate Metabolism; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Diabetes Complications; Diabetes Mellitus; Glyburide; Humans; Hyperlipidemias; Hypolipidemic Agents; Middle Aged; Patient Compliance | 1982 |
Effect of bezafibrate on plasma lipids, lipoproteins, apolipoproteins AI, AII and B and LCAT activity in hyperlipidemic, non-insulin-dependent diabetics.
Topics: Aged; Apolipoprotein A-II; Apolipoproteins; Apolipoproteins A; Apolipoproteins B; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Clofibrate; Clofibric Acid; Diabetes Mellitus; Female; Humans; Hyperlipoproteinemias; Lipids; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Phosphatidylcholine-Sterol O-Acyltransferase | 1982 |
[Lipid-lowering effect of etofibrate, bezafibrate and xanthinol nicotinate in patients with hyperlipoproteinemias].
Topics: Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Theophylline; Xanthinol Niacinate | 1982 |
[Comparative double-blind investigation of bezafibrate and clofibrate in patients with primary hyperlipoproteinaemia].
Topics: Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemias; Male; Placebos; Triglycerides | 1980 |
Steady-state kinetics of bezafibrate and clofibrate in healthy female volunteers.
Topics: Administration, Oral; Adult; Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Drug Administration Schedule; Female; Half-Life; Humans; Hypolipidemic Agents; Kinetics | 1980 |
[Comparison of the lipid-lowering agents clofibrate and bezafibrate in patients with hyperlipoproteinemias IIa and IIb].
Topics: Adult; Bezafibrate; Cholesterol; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Random Allocation; Triglycerides | 1981 |
Comparative study of once and 3-times daily regimens of bezafibrate in patients with primary hyperlipoproteinaemia.
Topics: Adult; Aged; Alkaline Phosphatase; Bezafibrate; Cholesterol; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Creatinine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipids; Male; Middle Aged; Urea | 1981 |
Improvement of hyperlipidaemia by bezafibrate treatment in RDT patients.
Topics: Adult; Bezafibrate; Cholesterol; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney Failure, Chronic; Middle Aged; Renal Dialysis; Triglycerides | 1981 |
[Behavior of high-density lipoproteins in drug lipid-lowering treatment].
Topics: Adult; Apoproteins; Bezafibrate; Cholesterol; Cholesterol, HDL; Clofibric Acid; Colestipol; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lipoproteins, HDL; Male; Middle Aged; Probucol | 1982 |
[Efficacy of bezafibrate and fenofibrate on elevated blood lipids in HLP type IIa, IIb and IV].
Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Clofibrate; Clofibric Acid; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipids; Male; Middle Aged; Propionates | 1982 |
Treatment of familial hypercholesterolemia with a combination of bezafibrate and guar.
Topics: Adult; Apolipoproteins; Bezafibrate; Body Weight; Cholesterol; Cholesterol, LDL; Clofibrate; Clofibric Acid; Drug Therapy, Combination; Female; Galactans; Humans; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Male; Mannans; Middle Aged; Plant Gums; Polysaccharides | 1982 |
[Treatment of hyperlipoproteinaemia in diabetic patients (author's transl)].
Topics: Adult; Aged; Bezafibrate; Blood Glucose; Cholesterol; Clofibrate; Clofibric Acid; Diabetes Complications; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Male; Middle Aged; Phospholipids; Placebos; Triglycerides | 1981 |
Comparison of the efficacy of simvastatin and standard fibrate therapy in the treatment of primary hypercholesterolemia and combined hyperlipidemia.
Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol, LDL; Clofibric Acid; Fatty Acids, Volatile; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides | 1995 |
Comparative efficacy and safety of ciprofibrate and sustained-release bezafibrate in patients with type II hyperlipidaemia.
Topics: Adult; Aged; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Delayed-Action Preparations; Female; Fibric Acids; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Male; Middle Aged; Triglycerides | 1996 |
Homocysteine elevation with fibrates: is it a class effect?
Topics: Adult; Bezafibrate; Clofibric Acid; Dietary Fats; Female; Fibric Acids; Homocysteine; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Triglycerides | 2001 |
Fish oil increases bile acid synthesis in male patients with hypertriglyceridemia.
Topics: Bezafibrate; Bile Acids and Salts; Blood Glucose; Body Mass Index; Chenodeoxycholic Acid; Cholesterol; Cholic Acid; Clofibric Acid; Cross-Over Studies; Fasting; Fish Oils; Gallstones; Humans; Hypertriglyceridemia; Insulin; Insulin Resistance; Lipids; Male; Middle Aged; Triglycerides | 2006 |
Decrease in triglyceride level by bezafibrate is related to reduction of recurrent coronary events: a Bezafibrate Infarction Prevention substudy.
Topics: Aged; Bezafibrate; Clofibric Acid; Female; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Male; Middle Aged; Prospective Studies; Risk Assessment; Risk Factors; Secondary Prevention; Triglycerides | 2006 |
98 other study(ies) available for bezafibrate and clofibric acid
Article | Year |
---|---|
Design, synthesis, and testing of potential antisickling agents. 4. Structure-activity relationships of benzyloxy and phenoxy acids.
Topics: Acetates; Animals; Antisickling Agents; Benzyl Compounds; Binding Sites; Glycolates; Humans; Mice; Models, Molecular; Oxygen; Phenoxyacetates; Structure-Activity Relationship; X-Ray Diffraction | 1984 |
A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPARalpha agonist with potent lipid-lowering activity.
Topics: Animals; Butyrates; DNA-Binding Proteins; Fenofibrate; Humans; Hypolipidemic Agents; Lipid Metabolism; Male; Mice; Nuclear Proteins; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Zinc Fingers | 1999 |
Substituted 2-[(4-aminomethyl)phenoxy]-2-methylpropionic acid PPARalpha agonists. 1. Discovery of a novel series of potent HDLc raising agents.
Topics: Animals; Apolipoprotein A-I; Cholesterol, HDL; Cholesterol, VLDL; Crystallography, X-Ray; Dogs; Dyslipidemias; Humans; Ligands; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Molecular; PPAR alpha; Propionates; Protein Structure, Tertiary; Rats; Rats, Wistar; Structure-Activity Relationship; Thiazoles; Triglycerides | 2007 |
Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Benzene Derivatives; Bezafibrate; Cell Line; Cercopithecidae; Clofibric Acid; Gemfibrozil; Herbicides; Humans; Hypolipidemic Agents; Indoleacetic Acids; Mice; Protein Subunits; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Structure-Activity Relationship | 2009 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
[A comparison of bezafibrate and clofibrate in type II B and type IV hyperlipoproteinemia].
Topics: Adult; Aged; Bezafibrate; Clofibrate; Clofibric Acid; Dose-Response Relationship, Drug; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Male; Middle Aged | 1979 |
Effect of bezafibrate and clofibric acid on the spectroscopic properties of the nitric oxide derivative of ferrous human hemoglobin.
Topics: 2,3-Diphosphoglycerate; Bezafibrate; Clofibric Acid; Diphosphoglyceric Acids; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Hemoglobins; Humans; Molecular Structure; Nitric Oxide; Phytic Acid; Protein Conformation; Spectrophotometry; Spectrum Analysis | 1992 |
Differential inhibition of long-chain acyl-CoA hydrolases by hypolipidemic drugs in vitro.
Topics: Animals; Bezafibrate; Clofibric Acid; Gemfibrozil; Hypolipidemic Agents; Liver; Male; Palmitoyl Coenzyme A; Palmitoyl-CoA Hydrolase; Rats; Rats, Inbred Strains; Subcellular Fractions | 1992 |
In vitro effect of clofibric acid derivatives on rat hepatic microsomal electron transport chains.
Topics: Animals; Bezafibrate; Clofibric Acid; Cytochromes b5; Electron Transport; Gemfibrozil; Kinetics; Male; Microsomes, Liver; NADH Dehydrogenase; NADPH Dehydrogenase; Rats; Rats, Inbred Strains | 1991 |
Interaction of LY171883 and other peroxisome proliferators with fatty-acid-binding protein isolated from rat liver.
Topics: Acetophenones; Animals; Bezafibrate; Carrier Proteins; Clofibric Acid; Electrophoresis, Polyacrylamide Gel; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fibric Acids; Male; Microbodies; Neoplasm Proteins; Nerve Tissue Proteins; Oleic Acid; Oleic Acids; Pyrimidines; Rats; Rats, Inbred F344; SRS-A; Tetrazoles | 1991 |
Effect of ciprofibrate, bezafibrate, and LY171883 on peroxisomal beta-oxidation in cultured rat, dog, and rhesus monkey hepatocytes.
Topics: Acetophenones; Animals; Autacoids; Azoles; Bezafibrate; Cells, Cultured; Clofibrate; Clofibric Acid; Dexamethasone; Dogs; Dose-Response Relationship, Drug; Female; Fibric Acids; Glucagon; Hypolipidemic Agents; In Vitro Techniques; Liver; Male; Microbodies; Microscopy, Electron; NAD; Oxidation-Reduction; Rats; Tetrazoles; Tyrosine Transaminase | 1990 |
Comparative studies on the influence of different fibrates on serum lipoproteins in endogenous hyperlipoproteinaemia.
Topics: Adult; Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Colestipol; Female; Fenofibrate; Gemfibrozil; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged; Probucol | 1991 |
Transitory deficit in high-density lipoproteins and apolipoprotein A-I.
Topics: Apolipoprotein A-I; Apolipoproteins A; Bezafibrate; Clofibric Acid; Drug Therapy, Combination; Fibric Acids; Humans; Hypolipidemic Agents; Lipoproteins, HDL; Male; Middle Aged; Probucol | 1990 |
Hepatic induction potency of hypolipidaemic drugs in the rat following long-term administration: influence of different dosing regimens.
Topics: Animals; Bezafibrate; Clofibric Acid; Fibric Acids; Glutathione Peroxidase; Hepatomegaly; Hypolipidemic Agents; Liver; Male; Microbodies; Rats | 1990 |
Effects of treatment with clofibrate, bezafibrate, and ciprofibrate on the metabolism of cholesterol in rat liver microsomes.
Topics: Animals; Bezafibrate; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Clofibrate; Clofibric Acid; Fibric Acids; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Sterol O-Acyltransferase | 1989 |
The comparative pharmacokinetics and gastric toxicity of bezafibrate and ciprofibrate in the rat.
Topics: Administration, Oral; Animals; Bezafibrate; Clofibric Acid; Dose-Response Relationship, Drug; Fibric Acids; Gastric Mucosa; Gastrins; Hypolipidemic Agents; Male; Neurosecretory Systems; Rats; Rats, Inbred F344; Stomach Ulcer | 1989 |
Fatty acid metabolism in hepatocytes cultured with hypolipidaemic drugs. Role of carnitine.
Topics: Animals; Bezafibrate; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Cells, Cultured; Clofibrate; Clofibric Acid; Fatty Acids; Fibric Acids; Glucagon; Humans; Hypolipidemic Agents; Insulin; Liver; Male; Rats; Rats, Inbred Strains | 1988 |
Gemfibrozil increases both apo A-I and apo E concentrations. Comparison to other lipid regulators in cholesterol-fed rats.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins E; Bezafibrate; Cholesterol, Dietary; Cholesterol, HDL; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Gemfibrozil; Male; Pentanoic Acids; Rats; Rats, Inbred Strains; Valerates | 1986 |
Assessment of gastric antisecretory effects of phenoxyisobutyrate derivatives in the rat and the mouse.
Topics: Administration, Oral; Animals; Bezafibrate; Carcinoid Tumor; Clofibrate; Clofibric Acid; Fibric Acids; Gastric Juice; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred F344; Species Specificity; Stomach Neoplasms; Time Factors | 1988 |
Interactions of inhibitors of carnitine palmitoyltransferase I and fibrates in cultured hepatocytes.
Topics: Acyltransferases; Animals; Bezafibrate; Carnitine O-Palmitoyltransferase; Cells, Cultured; Clofibrate; Clofibric Acid; Epoxy Compounds; Ethers, Cyclic; Fatty Acids; Fibric Acids; Isoenzymes; Liver; Male; Rats; Rats, Inbred Strains; Time Factors; Triglycerides | 1988 |
Conditions influencing the induction of peroxisomal beta-oxidation in cultured rat hepatocytes.
Topics: Animals; Bezafibrate; Catalase; Cell Survival; Clofibric Acid; Fibric Acids; Gemfibrozil; In Vitro Techniques; Liver; Male; Microbodies; Pentanoic Acids; Rats; Rats, Inbred F344 | 1986 |
Effects of bezafibrate on receptor-mediated and receptor-independent low density lipoprotein catabolism in type II hyperlipoproteinaemic subjects.
Topics: Adult; Apolipoproteins; Apolipoproteins B; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type II; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Receptors, Cell Surface; Receptors, LDL | 1982 |
[Improvement in diabetes control by treatment with bezafibrate].
Topics: Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hyperlipidemias; Insulin; Male; Sulfonylurea Compounds; Triglycerides | 1982 |
[Drug therapy of hypercholesterinemias (author's transl)].
Topics: Adult; Bezafibrate; Cholestyramine Resin; Clofibric Acid; Colestipol; Dextrothyroxine; Fenofibrate; Humans; Hypercholesterolemia; Neomycin; Nicotinic Acids; Sitosterols | 1980 |
Reduced LDL- and increased HDL-apoproteins in patients with hypercholesterolaemia under treatment with bezafibrate.
Topics: Adult; Aged; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins; Apolipoproteins B; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Clofibric Acid; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Triglycerides | 1981 |
[Bezafibrate and delayed action etofibrate in hyperlipidemia].
Topics: Bezafibrate; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Clofibric Acid; Delayed-Action Preparations; Humans; Hyperlipidemias; Lipoproteins, HDL; Lipoproteins, LDL; Triglycerides | 1983 |
The effect of bezafibrate and clofibrate on cholesterol ester metabolism in rabbit peritoneal macrophages stimulated with acetylated low density lipoproteins.
Topics: Animals; Ascitic Fluid; Bezafibrate; Cholesterol Esters; Clofibrate; Clofibric Acid; Lipoproteins, LDL; Macrophages; Rabbits; Sterol Esterase; Sterol O-Acyltransferase | 1983 |
Elevation of high density lipoprotein cholesterol (cHDL) and reduction of the total cholesterol/cHDL index in the treatment of hyperlipoproteinaemias IIb and IV with bezafibrate.
Topics: Adult; Aged; Bezafibrate; Cholesterol; Cholesterol, HDL; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipoproteins, HDL; Male; Middle Aged; Triglycerides | 1983 |
The short- and long-term effects of bezafibrate in the rat.
Topics: Animals; Bezafibrate; Carnitine O-Acetyltransferase; Catalase; Cholesterol; Clofibrate; Clofibric Acid; Female; Hypolipidemic Agents; Kinetics; Liver; Male; Microbodies; Microscopy, Electron; Organ Size; Organoids; Rats; Rats, Inbred Strains; Triglycerides | 1982 |
Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters.
Topics: Adult; Apolipoproteins; Bezafibrate; Blood Glucose; Body Weight; Cholesterol; Clofibrate; Clofibric Acid; Esters; Fatty Acids; Female; Humans; Insulin; Lipids; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Triglycerides | 1980 |
The effect of bezafibrate and clofibrate on cholesterol ester metabolism in 3T3 cells in smooth muscle cells in tissue culture.
Topics: Animals; Aorta; Bezafibrate; Cell Line; Cholesterol; Cholesterol Esters; Clofibrate; Clofibric Acid; Culture Techniques; Lipoproteins, LDL; Mice; Muscle, Smooth, Vascular; Swine | 1982 |
[Bezafibrate in primary hyperlipidemias (author's transl)].
Topics: Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipidemias; Hyperlipoproteinemias; Lipoprotein Lipase; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged | 1982 |
Effects of bezafibrate on the composition of very low density lipoproteins in type IV hyperlipoproteinemia.
Topics: Apolipoprotein C-I; Apolipoprotein C-II; Apolipoproteins; Apolipoproteins C; Apolipoproteins E; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipoproteins, VLDL; Male; Protein Conformation; Triglycerides | 1982 |
Specificity in the action of hypolipidemic drugs: increase of peroxisomal beta-oxidation largely dissociated from hepatomegaly and peroxisome proliferation in the rat.
Topics: Animals; Bezafibrate; Cell Division; Cell Fractionation; Clofibrate; Clofibric Acid; Female; Hepatomegaly; Hypolipidemic Agents; Male; Microbodies; Organ Size; Organoids; Rats; Rats, Inbred F344; Sex Factors | 1982 |
Bezafibrate: lack of effect on creatinine excretion and muscular proteins.
Topics: Bezafibrate; Clofibrate; Clofibric Acid; Creatine Kinase; Creatinine; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Isoenzymes; Kidney; Male; Middle Aged; Muscle Proteins; Muscles; Myoglobinuria | 1982 |
[What are the possibilities in the treatment of primary hyperlipidemia in diabetes mellitus?].
Topics: Bezafibrate; Clofibric Acid; Diabetes Complications; Humans; Hyperlipidemias; Hypolipidemic Agents | 1982 |
Elevated lipoprotein lipase activity in skeletal muscle tissue during treatment of hypertriglyceridaemic patients with bezafibrate.
Topics: Adipose Tissue; Adult; Bezafibrate; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipoprotein Lipase; Male; Middle Aged; Muscles | 1982 |
[Fat and renal failure--therapeutic aspects].
Topics: Acute Kidney Injury; Animals; Bezafibrate; Carnitine; Charcoal; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Infusions, Parenteral; Kidney Failure, Chronic; Lipids; Physical Exertion; Rats; Renal Dialysis | 1982 |
Treatment of uremic hypertriglyceridaemia with bezafibrate.
Topics: Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipidemias; Kidney Failure, Chronic; Lipid Metabolism; Lipoproteins; Male; Triglycerides | 1982 |
Bezafibrate treatment in primary hypercholesterolaemia. Possibility of intermittent treatment.
Topics: Animals; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Clofibric Acid; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, LDL; Mice; Microbodies; Rats; Time Factors | 1982 |
The effect of bezafibrate and clofibrate on microsomal ACAT and lysosomal cholesterol ester hydrolase activity in the cholesterol-fed rabbit aorta.
Topics: Acyltransferases; Animals; Aorta; Bezafibrate; Carboxylic Ester Hydrolases; Clofibrate; Clofibric Acid; Female; Hypolipidemic Agents; Lysosomes; Rabbits; Regression Analysis; Sterol Esterase; Sterol O-Acyltransferase | 1982 |
[Effect of bezafibrate on lipid and apoprotein levels in patients with idiopathic hypertriglyceridemia].
Topics: Adult; Aged; Apolipoproteins; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type III; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Male; Middle Aged; Triglycerides | 1982 |
[Effect of bezafibrate on the carbohydrate metabolism of 17 diabetics with hyperlipidemia].
Topics: Anticholesteremic Agents; Bezafibrate; Body Weight; Carbohydrate Metabolism; Clofibrate; Clofibric Acid; Diabetes Complications; Humans; Hyperlipidemias; Placebos | 1981 |
"In vitro" metabolism of bezafibrate by rat liver.
Topics: Animals; Bezafibrate; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Hydroxylation; Hypolipidemic Agents; In Vitro Techniques; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Rats; Subcellular Fractions | 1981 |
Effect of bezafibrate on the high-density lipoprotein subfractions HDL2 and HDL3 in primary hyperlipoproteinemia type IV.
Topics: Adult; Apolipoproteins; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemia Type IV; Lipids; Lipoproteins, HDL; Male; Middle Aged; Triglycerides | 1980 |
Lipids and lipoproteins in hyperlipidemia type IIa during treatment with different lipid lowering drugs.
Topics: Adolescent; Bezafibrate; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type II; Inositol; Lipids; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Male; Nicotinic Acids; Nicotinyl Alcohol; Xanthinol Niacinate | 1980 |
Clinical experience with bezafibrate.
Topics: Bezafibrate; Blood Glucose; Body Weight; Cholesterol; Clofibrate; Clofibric Acid; Coronary Disease; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Male; Triglycerides | 1980 |
Effects of clofibric acid and bezafibrate administration on activities of alkaline phosphatase and other enzymes in livers of rats.
Topics: Alkaline Phosphatase; Animals; Bezafibrate; Bilirubin; Clofibrate; Clofibric Acid; Glucuronates; Glucuronosyltransferase; Hexosyltransferases; Hypolipidemic Agents; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred Strains | 1981 |
[Rhabdomyolysis with acute renal failure due to bezafibrate].
Topics: Acute Kidney Injury; Bezafibrate; Clofibrate; Clofibric Acid; Humans; Male; Middle Aged; Muscular Diseases | 1981 |
Effects of bezafibrate on low HDL-cholesterol in patients with ischaemic cerebrovascular disease: a pilot study.
Topics: Adult; Bezafibrate; Cerebral Infarction; Cholesterol; Cholesterol, HDL; Clofibrate; Clofibric Acid; Humans; Hypolipidemic Agents; Ischemic Attack, Transient; Lipoproteins, HDL; Male; Middle Aged | 1981 |
Acute muscular syndrome after bezafibrate.
Topics: Bezafibrate; Clofibrate; Clofibric Acid; Dose-Response Relationship, Drug; Humans; Hypolipidemic Agents; Myoglobinuria | 1981 |
Peroxisomal fatty acid oxidation as detected by H2O2 production in intact perfused rat liver.
Topics: Animals; Bezafibrate; Catalase; Clofibric Acid; Fatty Acids; Hydrogen Peroxide; Hypolipidemic Agents; In Vitro Techniques; Liver; Male; Methanol; Microbodies; Organoids; Oxidation-Reduction; Perfusion; Rats; Rats, Inbred Strains | 1981 |
Clinical pharmacokinetics of bezafibrate in patients with impaired renal function.
Topics: Adult; Aged; Bezafibrate; Clofibrate; Clofibric Acid; Creatinine; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney Failure, Chronic; Kinetics; Male; Middle Aged | 1981 |
Comparative pharmacokinetics of 400 mg bezafibrate after a single oral administration of a new slow-release preparation and the currently available commercial form.
Topics: Administration, Oral; Adolescent; Adult; Bezafibrate; Clofibrate; Clofibric Acid; Delayed-Action Preparations; Female; Humans; Hypolipidemic Agents; Kinetics; Male | 1981 |
Effect of the hypolipidemic drug bezafibrate on the hepatic mixed function oxidase system of the rat: heterogeneity monooxygenase responses.
Topics: Animals; Bezafibrate; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Hypolipidemic Agents; Liver; Male; Mixed Function Oxygenases; Oxidoreductases; Rats; Rats, Inbred Strains; Spectrum Analysis | 1981 |
Pharmacokinetics of bezafibrate after single and multiple doses in the presence of renal failure.
Topics: Adult; Bezafibrate; Clofibrate; Clofibric Acid; Drug Administration Schedule; Female; Humans; Kidney Diseases; Kinetics; Male; Middle Aged | 1980 |
[The therapeutic efficacy of bezafibrate in hyperlipoproteinemias of various types].
Topics: Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hyperlipoproteinemia Type V; Hyperlipoproteinemias; Lipoproteins, HDL; Triglycerides | 1980 |
Changes in lipids and lipoproteins in patients with hyperlipidemia type IIb, IV and V treated with different lipid lowering drugs.
Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hyperlipoproteinemia Type V; Inositol; Lipoproteins; Nicotinic Acids; Xanthinol Niacinate | 1980 |
The effect of etofibrate retard, bezafibrate and procetofen.
Topics: Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Lipoproteins; Male; Middle Aged; Patient Compliance; Propionates; Triglycerides | 1980 |
[Clofibrate therapy in hypercholesterolemia. Reports on medium-long-term movements of HDL- cholesterol by the action of clofibrate].
Topics: Adult; Bezafibrate; Clofibrate; Clofibric Acid; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Male; Middle Aged | 1980 |
Lipid profiles on fibric-acid derivatives.
Topics: Bezafibrate; Cholesterol, HDL; Clofibric Acid; Female; Fibric Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids | 1994 |
Hypercholesterolemia treatment in a renal transplant patient.
Topics: Anticholesteremic Agents; Bezafibrate; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Humans; Hypercholesterolemia; Kidney Transplantation; Lovastatin; Male; Middle Aged; Postoperative Complications; Simvastatin | 1994 |
Creatinine rise after fibrate therapy in renal graft recipients.
Topics: Bezafibrate; Clofibric Acid; Creatinine; Female; Fenofibrate; Fibric Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Kidney Transplantation; Male | 1993 |
Fibrates modify rat hepatic fatty acid chain elongation and desaturation in vitro.
Topics: Acetyltransferases; Animals; Bezafibrate; Clofibric Acid; Cytosol; Fatty Acid Desaturases; Fatty Acid Elongases; Gemfibrozil; Liver; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 1993 |
Cytosolic lipogenic enzymes: effect of fibric acid derivatives in vitro.
Topics: Animals; Bezafibrate; Clofibric Acid; Cytosol; Enzyme Inhibitors; Fatty Acids; Gemfibrozil; Kinetics; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 1993 |
Abnormal lipid profiles on fibrate derivatives.
Topics: Bezafibrate; Cholesterol, HDL; Clofibric Acid; Fibric Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids | 1996 |
Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Bezafibrate; Bile; Bile Canaliculi; Clofibrate; Clofibric Acid; DNA Primers; Drug Resistance, Multiple; Fenofibrate; Fibric Acids; Gemfibrozil; Gene Expression; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Multigene Family; Phospholipids; RNA, Messenger; RNA, Ribosomal, 18S | 1996 |
Growth regulation by peroxisome proliferators: opposing activities in early and late G1.
Topics: Animals; Bezafibrate; Carcinogens; Cell Cycle; Cell Line; Clofibrate; Clofibric Acid; DNA; Fibric Acids; Gene Expression Regulation; Genes, Immediate-Early; Growth Substances; Mice; Microbodies; Pyrimidines; Signal Transduction; Time Factors; Transcriptional Activation | 1996 |
Bezafibrate and clofibric acid are novel inhibitors of phosphatidylcholine synthesis via the methylation of phosphatidylethanolamine.
Topics: Animals; Bezafibrate; Butyrates; Cells, Cultured; Choline-Phosphate Cytidylyltransferase; Clofibric Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Liver; Methylation; Methyltransferases; Microsomes; Nucleotidyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Wistar; Sulfhydryl Reagents | 1996 |
The role of phosphatidylethanolamine methylation in the secretion of very low density lipoproteins by cultured rat hepatocytes: rapid inhibition of phosphatidylethanolamine methylation by bezafibrate increases the density of apolipoprotein B48-containing
Topics: Animals; Apolipoprotein B-48; Apolipoproteins B; Bezafibrate; Cells, Cultured; Clofibric Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanolamine; Ethanolamines; Female; Leucine; Lipoproteins, VLDL; Liver; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Wistar; Specific Gravity; Tubercidin | 1996 |
Determination of bezafibrate, ciprofibrate and fenofibric acid in human plasma by high-performance liquid chromatography.
Topics: Bezafibrate; Calibration; Chromatography, High Pressure Liquid; Clofibric Acid; Fenofibrate; Fibric Acids; Humans; Hypolipidemic Agents; Reproducibility of Results; Sensitivity and Specificity | 1996 |
No effect of fibrates on synthesis of apolipoprotein(a) in primary cultures of cynomolgus monkey and human hepatocytes: apolipoprotein A-I synthesis increased.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins A; Bezafibrate; Cells, Cultured; Clofibrate; Clofibric Acid; Gemfibrozil; Humans; Liver; Macaca fascicularis | 1998 |
The effect of peroxisome proliferators on mitochondrial bioenergetics.
Topics: Animals; Bezafibrate; Calcium; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Energy Metabolism; Fenofibrate; Fibric Acids; Gemfibrozil; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxygen; Permeability; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Sprague-Dawley; Trichloroethylene | 1999 |
Effects of fibrate compounds on expression of plasminogen activator inhibitor-1 by cultured endothelial cells.
Topics: Bezafibrate; Cells, Cultured; Clofibric Acid; Endothelium, Vascular; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Plasminogen Activator Inhibitor 1; Pyrimidines; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription, Genetic | 1999 |
Statin + fibrate combination therapy fluvastatin with bezafibrate or ciprofibrate in high risk patients with vascular disease.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Bezafibrate; Cardiovascular Diseases; Clofibric Acid; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fibric Acids; Fluvastatin; Humans; Hyperlipidemias; Hypolipidemic Agents; Indoles; Male; Middle Aged; Pilot Projects; Treatment Outcome | 1999 |
Bezafibrate as differentiating factor of human myeloid leukemia cells.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Bezafibrate; Biomarkers; Cell Cycle; Cell Differentiation; Clofibric Acid; Gemfibrozil; Growth Inhibitors; HL-60 Cells; Humans; Integrin alphaXbeta2; K562 Cells; Leukemia, Myeloid; Lipopolysaccharide Receptors; U937 Cells | 1999 |
Acute renal failure after cardiopulmonary bypass: a possible association with drugs of the fibrate group.
Topics: Acute Kidney Injury; Aged; Anticholesteremic Agents; Bezafibrate; Cardiopulmonary Bypass; Clofibric Acid; Female; Fibric Acids; Humans; Male; Middle Aged; Rhabdomyolysis | 2000 |
Differences in the formation of PPARalpha-RXR/acoPPRE complexes between responsive and nonresponsive species upon fibrate administration.
Topics: Acyl-CoA Oxidase; Animals; Bezafibrate; Biopolymers; Cell Nucleus; Cells, Cultured; Clofibric Acid; Cytosol; Fibric Acids; Guinea Pigs; Humans; Hypolipidemic Agents; Liver; Male; Nuclear Proteins; Oxidoreductases; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; RNA, Messenger; Sp1 Transcription Factor; Transcription Factors | 2000 |
Fibrate-induced increase in blood urea and creatinine: is gemfibrozil the only innocuous agent?
Topics: Bezafibrate; Clofibric Acid; Creatinine; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Kidney Diseases; Kidney Transplantation; Postoperative Period; Retrospective Studies; Urea | 2000 |
Differential induction of stearoyl-CoA desaturase and acyl-CoA oxidase genes by fibrates in HepG2 cells.
Topics: Acyl-CoA Oxidase; Adipose Tissue; Animals; Bezafibrate; Clofibric Acid; Culture Media; Enzyme Induction; Fibric Acids; Humans; Hypolipidemic Agents; Liver; Male; Oxidoreductases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stearoyl-CoA Desaturase; Tumor Cells, Cultured | 2001 |
Fibrate-induced increase in blood urea and creatinine.
Topics: Bezafibrate; Blood Urea Nitrogen; Clofibric Acid; Creatinine; Fenofibrate; Fibric Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney Diseases | 2001 |
Effects of various fibrates on serum alkaline phosphatase activity.
Topics: Alkaline Phosphatase; Bezafibrate; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Retrospective Studies; Treatment Outcome | 2002 |
Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFkappa B-C/EBP-beta complex formation.
Topics: Animals; Bezafibrate; C-Reactive Protein; CCAAT-Enhancer-Binding Protein-beta; Cell Nucleus; Clofibric Acid; Down-Regulation; Fibric Acids; Hepatocytes; Humans; Hypolipidemic Agents; Interleukin-1; Mice; Mice, Knockout; NF-kappa B; NF-kappa B p50 Subunit; Protein Binding; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transcription, Genetic; Transfection | 2003 |
Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells.
Topics: Bezafibrate; Clofibrate; Clofibric Acid; Disease Models, Animal; Drug Synergism; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma, Embryonal; RNA, Messenger; Simvastatin; Time Factors; Transcription Factors; Tumor Cells, Cultured | 2003 |
PPARalpha agonists stimulate progastrin production in human colorectal carcinoma cells.
Topics: Bezafibrate; Cell Proliferation; Clofibrate; Clofibric Acid; Colorectal Neoplasms; Fenofibrate; Fibric Acids; Gastrins; Gemfibrozil; Humans; Hypolipidemic Agents; Ligands; Peroxisome Proliferator-Activated Receptors; Protein Precursors; Pyrimidines; Radioimmunoassay; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Vasodilator Agents | 2004 |
Mitochondrial respiratory chain dysfunction, a non-receptor-mediated effect of synthetic PPAR-ligands: biochemical and pharmacological implications.
Topics: Bezafibrate; Cell Differentiation; Cell Division; Clofibric Acid; Dose-Response Relationship, Drug; Electron Transport; Gemfibrozil; HL-60 Cells; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Ligands; Mitochondria; Receptors, Cytoplasmic and Nuclear; Thiazolidinediones; Transcription Factors | 2004 |
Determination of some acidic drugs in surface and sewage treatment plant waters by capillary electrophoresis-electrospray ionization-mass spectrometry.
Topics: Acids; Bezafibrate; Clofibric Acid; Electrophoresis, Capillary; Naproxen; Pharmaceutical Preparations; Sewage; Spectrometry, Mass, Electrospray Ionization; Water Pollutants, Chemical | 2004 |
Differential associations of statin and fibrate treatment with carotid arterial remodeling.
Topics: Adult; Atorvastatin; Bezafibrate; Body Mass Index; Carotid Arteries; Cholesterol, HDL; Clofibric Acid; Cohort Studies; Dyslipidemias; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fibric Acids; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Male; Middle Aged; Multivariate Analysis; Pravastatin; Pyridines; Pyrroles; Risk Factors; Simvastatin; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography | 2005 |
Separation of fibrate-type antihyperlipidemic drugs by capillary electrophoresis and their quantitation in pharmaceuticals.
Topics: Bezafibrate; Buffers; Clofibric Acid; Electrophoresis, Capillary; Fibric Acids; Gemfibrozil; Hydrogen-Ion Concentration; Hypolipidemic Agents; Pharmaceutical Preparations; Reproducibility of Results; Temperature; Time Factors | 2006 |
Effects of lipid-lowering pharmaceuticals bezafibrate and clofibric acid on lipid metabolism in fathead minnow (Pimephales promelas).
Topics: Acyl-CoA Oxidase; Animals; Bezafibrate; Clofibric Acid; Cyprinidae; Female; Hypolipidemic Agents; Lipid Metabolism; Male; Ovum; PPAR alpha; Vitellogenins; Water Pollutants, Chemical | 2009 |
Regulation of CYP4A expression by bezafibrate in primary culture of rat and human hepatocytes: interspecies difference and influence of N-acetylcysteine.
Topics: Acetylcysteine; Adult; Aged; Animals; Bezafibrate; Cells, Cultured; Clofibric Acid; Cytochrome P-450 CYP4A; Female; Gene Expression Regulation; Hepatocytes; Humans; Hypolipidemic Agents; Male; Middle Aged; Rats; Rats, Wistar; RNA, Messenger; Species Specificity | 2009 |
A clinical puzzle: fibrates and homocysteine elevation: editorial to: "fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine" by M. Lever et al.
Topics: Animals; Betaine; Bezafibrate; Clofibric Acid; Dyslipidemias; Folic Acid; Homocysteine; Humans; Hypolipidemic Agents; Metabolic Syndrome | 2009 |
Differential induction of stearoyl-CoA desaturase 1 and 2 genes by fibrates in the liver of rats.
Topics: Animals; Bezafibrate; Clofibric Acid; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Fenofibrate; Gene Expression Regulation; Liver; Male; Rats; Rats, Wistar; RNA, Messenger; Stearoyl-CoA Desaturase | 2012 |
Induction of 1-acylglycerophosphocholine acyltransferase genes by fibrates in the liver of rats.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Animals; Bezafibrate; Clofibric Acid; Fatty Acids; Fenofibrate; Fibric Acids; Gene Expression; Gene Expression Regulation; Liver; Male; Microsomes, Liver; Phosphatidylcholines; Rats; Rats, Wistar; RNA, Messenger; Stearoyl-CoA Desaturase | 2012 |
Evaluating the fate of six common pharmaceuticals using a reactive transport model: insights from a stream tracer test.
Topics: Adsorption; Bezafibrate; Chromatography, High Pressure Liquid; Clofibric Acid; Ibuprofen; Metoprolol; Models, Theoretical; Naproxen; Pharmaceutical Preparations; Rivers; Sensitivity and Specificity; Sweden; Tandem Mass Spectrometry; Water Movements; Water Pollutants, Chemical | 2013 |
Fibrates reduce triacylglycerol content by upregulating adipose triglyceride lipase in the liver of rats.
Topics: Animals; Bezafibrate; Clofibric Acid; Fatty Liver; Fenofibrate; Lipase; Lipid Peroxidation; Liver; Male; Molecular Targeted Therapy; PPAR alpha; Rats; Rats, Wistar; Triglycerides; Up-Regulation | 2013 |
A simple and sensitive method for the determination of fibric acids in the liver by liquid chromatography.
Topics: Acyl-CoA Oxidase; Animals; Bezafibrate; Chromatography, High Pressure Liquid; Clofibric Acid; Fenofibrate; Fibric Acids; Liver; Male; PPAR alpha; Rats; Rats, Wistar; Reproducibility of Results; RNA, Messenger | 2014 |
Degradation of lipid regulators by the UV/chlorine process: Radical mechanisms, chlorine oxide radical (ClO
Topics: Ammonia; Bezafibrate; Chlorine; Chlorine Compounds; Clofibric Acid; Disinfection; Gemfibrozil; Halogenation; Hydroxyl Radical; Hypolipidemic Agents; Kinetics; Oxidation-Reduction; Photolysis; Ultraviolet Rays; Vibrio; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2018 |