Page last updated: 2024-08-23

bezafibrate and carnitine

bezafibrate has been researched along with carnitine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's1 (6.25)18.2507
2000's2 (12.50)29.6817
2010's11 (68.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Agius, L; Alberti, KG; Gerondaes, P1
Heidland, A; Hörl, M; Hörl, WH1
Fusegawa, H; Kawashima, N; Sato, F; Shindo, R1
Aubey, F; Bastin, J; Djouadi, F; Schlemmer, D1
Aubey, F; Bastin, J; Djouadi, F; Ruiter, JP; Schlemmer, D; Strauss, AW; Wanders, RJ1
Fukuda, S; Hasegawa, Y; Kobayashi, H; Li, H; Mushimoto, Y; Purevsuren, J; Yamaguchi, S1
Chida, J; Kido, H; Yamaguchi, M; Yao, D; Yao, M1
Fukao, T; Fukuda, S; Furui, M; Hasegawa, Y; Kobayashi, H; Li, H; Mushimoto, Y; Purevsuren, J; Takahashi, T; Taketani, T; Yamada, K; Yamaguchi, S1
Ando, S; Arai, S; Asaka, I; Higaki, Y; Hitomi, H; Kaneoka, H; Kurose, Y; Nakashima, H; Osafune, K; Saito, T; Sakurai, H; Sudo, M; Tanaka, A; Yamada, K; Yamaguchi, S; Yasuno, T1
Fukuda, T; Hiroki, M; Ishii, A; Shigematsu, Y; Shioya, A; Sugie, H; Takuma, H; Tamaoka, A; Yamaguchi, S1
Aoyama, Y; Densupsoontorn, N; Fukao, T; Jirapinyo, P; Sathienkijkanchai, A; Vatanavicharn, N; Wasant, P; Yamada, K; Yamaguchi, S1
Ding, Y; Li, X; Liu, Y; Ma, Y; Song, J; Wang, Q; Yang, Y1
Bo, R; Fukuda, S; Hasegawa, Y; Kobayashi, H; Mushimoto, Y; Purevsuren, J; Takahashi, T; Taketani, T; Yamada, K; Yamaguchi, S1
Barger, JL; Cray, NL; Hester, SN; Mastaloudis, A; Newton, MA; Prolla, TA; Pugh, TD; Vann, JM; Weindruch, R; Wood, SM1

Other Studies

16 other study(ies) available for bezafibrate and carnitine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Fatty acid metabolism in hepatocytes cultured with hypolipidaemic drugs. Role of carnitine.
    The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1

    Topics: Animals; Bezafibrate; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Cells, Cultured; Clofibrate; Clofibric Acid; Fatty Acids; Fibric Acids; Glucagon; Humans; Hypolipidemic Agents; Insulin; Liver; Male; Rats; Rats, Inbred Strains

1988
[Fat and renal failure--therapeutic aspects].
    Klinische Wochenschrift, 1982, Volume: 60, Issue:15

    Topics: Acute Kidney Injury; Animals; Bezafibrate; Carnitine; Charcoal; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Infusions, Parenteral; Kidney Failure, Chronic; Lipids; Physical Exertion; Rats; Renal Dialysis

1982
[Case of secondary carnitine deficiency (in a patient undergoing hemodialysis), developing rhabdomyolysis due to dehydration and the action of a hypolipemic agent].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1993, Dec-10, Volume: 82, Issue:12

    Topics: Adult; Bezafibrate; Carnitine; Dehydration; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Rhabdomyolysis

1993
Peroxisome proliferator activated receptor delta (PPARdelta) agonist but not PPARalpha corrects carnitine palmitoyl transferase 2 deficiency in human muscle cells.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:3

    Topics: Adult; Bezafibrate; Butyrates; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Humans; Hypolipidemic Agents; Muscle Fibers, Skeletal; Palmitic Acid; Phenylurea Compounds; Point Mutation; PPAR gamma; Thiazoles; Tritium

2005
Bezafibrate increases very-long-chain acyl-CoA dehydrogenase protein and mRNA expression in deficient fibroblasts and is a potential therapy for fatty acid oxidation disorders.
    Human molecular genetics, 2005, Sep-15, Volume: 14, Issue:18

    Topics: Acyl-CoA Dehydrogenase, Long-Chain; Bezafibrate; Blotting, Western; Carnitine; DNA Primers; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Lipid Metabolism, Inborn Errors; Mitochondria; Mutation, Missense; Palmitates; Peroxisome Proliferator-Activated Receptors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2005
Effect of heat stress and bezafibrate on mitochondrial beta-oxidation: comparison between cultured cells from normal and mitochondrial fatty acid oxidation disorder children using in vitro probe acylcarnitine profiling assay.
    Brain & development, 2010, Volume: 32, Issue:5

    Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenase, Long-Chain; Bezafibrate; Carnitine; Cells, Cultured; Child; Fatty Acids; Fibroblasts; Hot Temperature; Humans; Hypolipidemic Agents; Lipid Metabolism, Inborn Errors; Mitochondria; Mitochondrial Diseases; Oxidation-Reduction; Stress, Physiological

2010
Bezafibrate upregulates carnitine palmitoyltransferase II expression and promotes mitochondrial energy crisis dissipation in fibroblasts of patients with influenza-associated encephalopathy.
    Molecular genetics and metabolism, 2011, Volume: 104, Issue:3

    Topics: Adenosine Triphosphate; Base Sequence; Bezafibrate; Blotting, Western; Brain Diseases, Metabolic; Carnitine; Carnitine O-Palmitoyltransferase; DNA Primers; Energy Metabolism; Fibroblasts; Gene Expression Regulation; Genomics; Hot Temperature; Humans; Influenza, Human; Japan; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Mitochondria; Molecular Sequence Data; Peroxisome Proliferator-Activated Receptors; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Time Factors

2011
Bezafibrate can be a new treatment option for mitochondrial fatty acid oxidation disorders: evaluation by in vitro probe acylcarnitine assay.
    Molecular genetics and metabolism, 2012, Volume: 107, Issue:1-2

    Topics: Bezafibrate; Carboxylic Acids; Carnitine; Cells, Cultured; Fatty Acids; Fibroblasts; Humans; Mitochondrial Diseases; Oxidation-Reduction

2012
Functional analysis of iPSC-derived myocytes from a patient with carnitine palmitoyltransferase II deficiency.
    Biochemical and biophysical research communications, 2014, May-30, Volume: 448, Issue:2

    Topics: Bezafibrate; Carnitine; Carnitine O-Palmitoyltransferase; Cell Differentiation; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Humans; Male; Metabolism, Inborn Errors; Muscle Cells; Palmitoylcarnitine; Pluripotent Stem Cells; Young Adult

2014
Amelioration of acylcarnitine profile using bezafibrate and riboflavin in a case of adult-onset glutaric acidemia type 2 with novel mutations of the electron transfer flavoprotein dehydrogenase (ETFDH) gene.
    Journal of the neurological sciences, 2014, Nov-15, Volume: 346, Issue:1-2

    Topics: Adult; Bezafibrate; Carnitine; Drug Therapy, Combination; Electron-Transferring Flavoproteins; Humans; Hypolipidemic Agents; Iron-Sulfur Proteins; Multiple Acyl Coenzyme A Dehydrogenase Deficiency; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Riboflavin; Treatment Outcome

2014
Carnitine-acylcarnitine translocase deficiency: Two neonatal cases with common splicing mutation and in vitro bezafibrate response.
    Brain & development, 2015, Volume: 37, Issue:7

    Topics: Bezafibrate; Carnitine; Carnitine Acyltransferases; Cells, Cultured; Child, Preschool; Fatal Outcome; Female; Fibroblasts; Genes, Lethal; Humans; Hypolipidemic Agents; In Vitro Techniques; Infant; Infant, Newborn; Lipid Metabolism, Inborn Errors; Male; Membrane Transport Proteins; Mitochondrial Diseases; Mutation; Treatment Outcome

2015
Very long-chain acyl-coenzyme A dehydrogenase deficiency in Chinese patients: eight case reports, including one case of prenatal diagnosis.
    European journal of medical genetics, 2015, Volume: 58, Issue:3

    Topics: Acyl-CoA Dehydrogenase, Long-Chain; Acyl-CoA Dehydrogenases; Amniotic Fluid; Ascorbic Acid; Asian People; Bezafibrate; Carnitine; Case-Control Studies; China; Chromatography, Liquid; Congenital Bone Marrow Failure Syndromes; DNA, Complementary; Exons; Female; Genetic Testing; Heterozygote; Humans; Infant; Infant Formula; Infant, Newborn; Lipid Metabolism, Inborn Errors; Male; Mitochondrial Diseases; Muscular Diseases; Mutation, Missense; Neonatal Screening; Prenatal Diagnosis; Sequence Alignment; Sequence Analysis, DNA; Tandem Mass Spectrometry; Treatment Outcome; Triglycerides; Vitamin B Complex

2015
Efficacy of bezafibrate on fibroblasts of glutaric acidemia type II patients evaluated using an in vitro probe acylcarnitine assay.
    Brain & development, 2017, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Age of Onset; Bezafibrate; Carnitine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Activators; Female; Fibroblasts; Humans; Infant; Infant, Newborn; Lipid Regulating Agents; Male; Multiple Acyl Coenzyme A Dehydrogenase Deficiency; Palmitoylcarnitine; Peroxisome Proliferator-Activated Receptors; Skin

2017
Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics.
    Aging cell, 2017, Volume: 16, Issue:4

    Topics: 2,4-Dinitrophenol; Adipose Tissue, White; Aging; Animals; Bezafibrate; Caloric Restriction; Carnitine; Citrate (si)-Synthase; Gene Expression Profiling; Gene Expression Regulation; Glycated Hemoglobin; Interferon-gamma; Male; Metformin; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Muscle, Skeletal; Myocardium; Neocortex; Pioglitazone; Quercetin; Resveratrol; Sirtuin 3; Stilbenes; Thiazolidinediones; Tumor Necrosis Factor-alpha

2017