Page last updated: 2024-08-25

bexarotene and lg 100268

bexarotene has been researched along with lg 100268 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's4 (33.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berger, E; Boehm, MF; Davies, JA; Heyman, RA; Mais, DE; McClurg, MR; Suto, CM; Wagoner, M; Zhang, L; Zhi, L1
Chandraratna, RA; Thacher, SM; Vasudevan, J1
Auwerx, J; Dallongeville, J; Heyman, RA; Kosykh, V; Schoonjans, K; Staels, B; Vu-Dac, N1
Bischoff, ED; Boehm, MF; Cesario, RM; Crombie, DL; Davies, PJ; Hamann, LG; Heyman, RA; Jow, L; Mondon, CE; Mukherjee, R; Nadzan, AM; Paterniti, JR1
Allegretto, EA; Chandraratna, RA; Fitzgerald, P; Heyman, RA; Teng, M1
Howell, SR; Shirley, MA; Ulm, EH1
Hede, K1
Brose, HL; Gould, MN; Haag, JD; Hitt, AA; Hu, R; Kim, K; Lindstrom, MJ; Lubet, RA; Mau, B; Monson, DM; Steele, VE; Waller, JL; Watson, PA; Woditschka, S; Zheng, Y1
Choi, C; Couture, MC; Dupéré-Richer, D; Hanna, N; Lagodich, M; Miller, WH; Pettersson, F1
Carroll, M; Glantz, ST; Kasner, MT; Sanchez, PV; Scotland, S1
Ben Aissa, M; Collins, NC; Koster, KP; LaDu, MJ; Lee, SH; Luo, J; Tai, LM; Thatcher, GRJ; Wang, YT1
Ko, SG; Seo, HS; Shin, YC; Woo, JK1

Reviews

1 review(s) available for bexarotene and lg 100268

ArticleYear
Therapeutic applications for ligands of retinoid receptors.
    Current pharmaceutical design, 2000, Volume: 6, Issue:1

    Topics: Animals; Drug Design; Humans; Ligands; Receptors, Retinoic Acid; Retinoids; Structure-Activity Relationship

2000

Other Studies

11 other study(ies) available for bexarotene and lg 100268

ArticleYear
Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells.
    Journal of medicinal chemistry, 1995, Aug-04, Volume: 38, Issue:16

    Topics: Apoptosis; Bexarotene; Binding, Competitive; Cell Line; Drug Design; Humans; Leukemia, Promyelocytic, Acute; Ligands; Niacin; Nicotinic Acids; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Structure-Activity Relationship; Tetrahydronaphthalenes; Transcription Factors; Transglutaminases; Tumor Cells, Cultured

1995
Retinoids increase human apolipoprotein A-11 expression through activation of the retinoid X receptor but not the retinoic acid receptor.
    Molecular and cellular biology, 1996, Volume: 16, Issue:7

    Topics: Apolipoprotein A-II; Apolipoproteins E; Base Sequence; Benzoates; Bexarotene; Carcinoma, Hepatocellular; Cloning, Molecular; DNA-Binding Proteins; Female; Gene Expression Regulation; Genomic Library; HeLa Cells; Humans; Kinetics; Liver Neoplasms; Molecular Sequence Data; Nicotinic Acids; Oligodeoxyribonucleotides; Placenta; Pregnancy; Receptors, Retinoic Acid; Regulatory Sequences, Nucleic Acid; Retinoid X Receptors; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Transcription Factors; Transcription, Genetic; Transfection; Tretinoin; Tumor Cells, Cultured

1996
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists.
    Nature, 1997, Mar-27, Volume: 386, Issue:6623

    Topics: Animals; Bexarotene; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Resistance; Ligands; Mice; Mice, Inbred C57BL; Mice, Obese; Nicotinic Acids; Obesity; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection

1997
Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status.
    Cancer research, 1997, Jul-01, Volume: 57, Issue:13

    Topics: Alitretinoin; Aminobenzoates; Antineoplastic Agents; Benzoates; Bexarotene; Breast Neoplasms; Cell Division; Chromans; Female; Humans; Nicotinic Acids; Nuclear Proteins; Receptors, Estrogen; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured

1997
Effects of retinoid treatment of rats on hepatic microsomal metabolism and cytochromes P450. Correlation between retinoic acid receptor/retinoid x receptor selectivity and effects on metabolic enzymes.
    Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:3

    Topics: Animals; Bexarotene; Cytochrome P-450 Enzyme System; Isoenzymes; Male; Microsomes, Liver; Molecular Structure; Nicotinic Acids; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Tretinoin

1998
Rexinoids may be ready for prime time in prevention, but challenges remain.
    Journal of the National Cancer Institute, 2004, Dec-15, Volume: 96, Issue:24

    Topics: Animals; Anticarcinogenic Agents; Bexarotene; Breast Neoplasms; Clinical Trials as Topic; Disease Models, Animal; Female; Humans; Nicotinic Acids; Piperidines; Retinoid X Receptors; Tetrahydronaphthalenes; Thiophenes

2004
Neu-induced retroviral rat mammary carcinogenesis: a novel chemoprevention model for both hormonally responsive and nonresponsive mammary carcinomas.
    Cancer research, 2006, Jul-01, Volume: 66, Issue:13

    Topics: Animals; Anticarcinogenic Agents; Bexarotene; Body Weight; Disease Models, Animal; Female; Genes, erbB-2; Genetic Vectors; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Nicotinic Acids; Rats; Rats, Inbred WF; Retroviridae; Tamoxifen; Tetrahydronaphthalenes

2006
Rexinoids modulate steroid and xenobiotic receptor activity by increasing its protein turnover in a calpain-dependent manner.
    The Journal of biological chemistry, 2008, Aug-08, Volume: 283, Issue:32

    Topics: Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bexarotene; Calpain; Cell Line, Tumor; Gene Expression Regulation; Humans; Nicotinic Acids; Nucleic Acid Synthesis Inhibitors; Pregnane X Receptor; Protein Binding; Receptors, Steroid; Retinoid X Receptors; Rifampin; Tetrahydronaphthalenes

2008
Induced differentiation of acute myeloid leukemia cells by activation of retinoid X and liver X receptors.
    Leukemia, 2014, Volume: 28, Issue:4

    Topics: Bexarotene; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Cell Line, Tumor; Humans; Hydrocarbons, Fluorinated; Leukemia, Myeloid, Acute; Liver X Receptors; Nicotinic Acids; Orphan Nuclear Receptors; Proto-Oncogene Proteins; Retinoid X Receptors; Sulfonamides; Tetrahydronaphthalenes; Trans-Activators; Tretinoin

2014
Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo.
    The Journal of biological chemistry, 2014, Oct-31, Volume: 289, Issue:44

    Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Apolipoproteins E; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Bexarotene; Disks Large Homolog 4 Protein; Drug Evaluation, Preclinical; Genotype; Guanylate Kinases; Humans; Lipoproteins; Liver; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Transgenic; Nicotinic Acids; Organ Size; Peptide Fragments; Retinoid X Receptors; Solubility; Tetrahydronaphthalenes

2014
Identification of biomarkers regulated by rexinoids (LGD1069, LG100268 and Ro25-7386) in human breast cells using Affymetrix microarray.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Anticarcinogenic Agents; Bexarotene; Biomarkers, Tumor; Breast; Breast Neoplasms; Cell Proliferation; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Microarray Analysis; Neoplasm Proteins; Nicotinic Acids; Retinoid X Receptors; Tetrahydronaphthalenes

2015