Page last updated: 2024-08-25

bexarotene and isotretinoin

bexarotene has been researched along with isotretinoin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dallongeville, J; Fruchart, JC; Gervois, P; Kooistra, T; Kosykh, V; Princen, HM; Staels, B; Torra, IP; Vu-Dac, N1
Anderson, B; Smith, MA1
Balitrand, N; Boelle, PY; Cassinat, B; Chomienne, C; Cras, A; Darsin-Bettinger, D; Politis, B; Toubert, ME1
Adamkova, K; Chlapek, P; Dobrotkova, V; Jezova, M; Mazanek, P; Sterba, J; Veselska, R1
Ding, Y; Dvornikov, AV; Ekker, SC; Herrmann, J; Hsiai, TK; Kim, M; Lin, X; Lowerison, M; Ma, X; Norton, N; Qiu, Q; Wang, Y; Wang, Z; Xu, X; Yu, Y; Zhang, H; Zhu, P1

Reviews

1 review(s) available for bexarotene and isotretinoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for bexarotene and isotretinoin

ArticleYear
Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids.
    The Journal of clinical investigation, 1998, Aug-01, Volume: 102, Issue:3

    Topics: Adult; Apolipoprotein C-III; Apolipoproteins C; Benzoates; Bexarotene; Carcinoma, Hepatocellular; Cells, Cultured; Dimerization; Double-Blind Method; Gene Expression Regulation; HeLa Cells; Humans; Hypertriglyceridemia; Isotretinoin; Liver; Liver Neoplasms; Male; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1998
Bexarotene via CBP/p300 induces suppression of NF-κB-dependent cell growth and invasion in thyroid cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jan-15, Volume: 18, Issue:2

    Topics: Antigens, Differentiation; Antineoplastic Agents; Bexarotene; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; E1A-Associated p300 Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Isotretinoin; Male; Middle Aged; Neoplasm Invasiveness; NF-kappa B; Receptors, Retinoic Acid; Retinoid X Receptor gamma; Tetrahydronaphthalenes; Thyroid Neoplasms; Transcription, Genetic; Transcriptional Activation; Treatment Outcome; Tretinoin

2012

Other Studies

4 other study(ies) available for bexarotene and isotretinoin

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Where to next with retinoids for cancer therapy?
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:10

    Topics: Alitretinoin; Antineoplastic Agents; Bexarotene; Humans; Isotretinoin; Neoplasms; Retinoids; Tetrahydronaphthalenes; Tretinoin

2001
Prediction of neuroblastoma cell response to treatment with natural or synthetic retinoids using selected protein biomarkers.
    PloS one, 2019, Volume: 14, Issue:6

    Topics: Adolescent; Antineoplastic Agents; Bexarotene; Biomarkers, Pharmacological; Cell Line, Tumor; Cell Proliferation; Child; Child, Preschool; DEAD-box RNA Helicases; Drug Resistance, Neoplasm; Female; Fenretinide; HMGA1a Protein; HMGA2 Protein; Homeodomain Proteins; Humans; Infant; Infant, Newborn; Isotretinoin; Male; Nervous System Neoplasms; Neuroblastoma; Paraffin Embedding; Pre-B-Cell Leukemia Transcription Factor 1; Tissue Fixation; Tretinoin; Young Adult

2019
Retinoid X receptor alpha is a spatiotemporally predominant therapeutic target for anthracycline-induced cardiotoxicity.
    Science advances, 2020, Volume: 6, Issue:5

    Topics: Animals; Bexarotene; Cardiotonic Agents; Cardiotoxicity; Disease Models, Animal; Endothelial Cells; Heart; Humans; Isotretinoin; Myocardium; Neoplasms; Pericardium; Retinoid X Receptor alpha; Zebrafish; Zonula Occludens-1 Protein

2020