bexarotene has been researched along with alitretinoin in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (31.03) | 18.2507 |
| 2000's | 11 (37.93) | 29.6817 |
| 2010's | 6 (20.69) | 24.3611 |
| 2020's | 3 (10.34) | 2.80 |
| Authors | Studies |
|---|---|
| Cameron, JF; Chao, WR; Dawson, MI; Hobbs, PD; Jong, L; Lee, MO; Pfahl, M; Shroot, B | 1 |
| Ebisawa, M; Eisenmann, G; Eyrolles, L; Fukasawa, H; Gronemeyer, H; Hashimoto, Y; Kagechika, H; Kawachi, E; Shudo, K; Umemiya, H | 1 |
| Hibi, S; Hida, T; Kikuchi, K; Nagai, M; Tai, K; Yoshimura, H | 1 |
| de Lera, AR; Domínguez, B; Sussman, F; Vega, MJ | 1 |
| de Lera, AR; Ortiz, MA; Pereira, R; Pérez-Rodríguez, S; Piedrafita, FJ; Rodríguez-Barrios, F | 1 |
| Atigadda, VR; Boerma, LJ; Brouillette, WJ; Christov, K; Desphande, A; Grubbs, CJ; Lobo-Ruppert, S; Moeinpour, FL; Muccio, DD; Smith, CD; Vines, KK; Xia, G | 1 |
| Atigadda, VR; Boerma, LJ; Brouillette, WJ; Desphande, A; Grubbs, CJ; Lobo-Ruppert, S; Muccio, DD; Smith, CD; Xia, G | 1 |
| Atigadda, VR; Bland, KI; Brouillette, WJ; Deshpande, A; Grubbs, CJ; Kedishvili, N; Krontiras, H; Muccio, DD; Smith, CD; Wu, L; Xia, G | 1 |
| Achenbach, J; Heitel, P; Merk, D; Moser, D; Proschak, E | 1 |
| Fujihara, M; Ito, S; Kakuta, H; Kawasaki, M; Makishima, M; Motoyama, T; Nakano, S; Nishioka, H; Takamura, Y; Takeuchi, Y; Takioku, M; Tokiwa, H; Watanabe, M; Yamada, S | 1 |
| Arnold, LA; Ashton, JM; Battaglia, N; Dokholyan, NV; Fujihara, M; Gerber, SA; Hansen, JN; Hopson, R; Jian, Y; Jurutka, PW; Kakuta, H; Kawar, N; Khazan, N; Kim, KK; Kishor, K; Linehan, DC; Milano, MT; Miyamoto, H; Moore, RG; Moore, T; Nayak, S; Ojha, D; Pandita, R; Rowswell-Turner, RB; Schor, NF; Sharon, A; Singh, AP; Singh, NA; Singh, RK; Snyder, CWA; Strawderman, M; Tabdanov, ED; Takamura, Y; Teramoto, Y; Wang, J; Yano, N | 1 |
| Athar, M; Atigadda, VR; Belyaeva, OV; Chang, PL; Chattopadhyay, D; Chou, CF; Elmets, CA; Grubbs, CJ; Kashyap, MP; Kedishvili, NY; Melo, N; Muccio, DD; Renfrow, MB; Sinha, R; Yang, Z | 1 |
| Dawson, MI; Eckert, RL; Fuchs, E; Hong, WK; Kurie, JM; Lee, HY; Lotan, R; Nesbitt, JC; Walsh, GL | 1 |
| Commes, T; Defacque, H; Marti, J; Piquemal, D; Rochette-Egly, C; Sévilla, C | 1 |
| Allegretto, EA; Chandraratna, RA; Fitzgerald, P; Heyman, RA; Teng, M | 1 |
| Hendriks, HF; Kaptein, A; Kooistra, T; Neele, DM; Princen, HM; Twisk, J | 1 |
| Budel, V; Cahen, P; Chaboteaux, C; Darro, F; Decaestecker, C; Kiss, R; Leblond, B; Nogaret, JM; Pétein, M; Pourrias, B; Ramos, C; Schoofs, A; Vianna, A | 1 |
| Hewson, QC; Lova, PE; Malcolm, AJ; Pearson, AD; Redfern, CP | 1 |
| Anderson, B; Smith, MA | 1 |
| Chu, F; Guo, Z; Huang, N | 1 |
| Li, D; Li, T; Samuels, HH; Tian, H; Wang, F | 1 |
| Foss, F; Gorgun, G | 1 |
| Hewson, QC; Lovat, PE; Pearson, AD; Redfern, CP | 1 |
| Simeone, AM; Tari, AM | 1 |
| Mei, JH; Wang, MW | 1 |
| DiPette, D; Guleria, R; Joshi, S; Pan, J; Singh, US | 1 |
| Chai, D; He, B; Pu, J; Shan, P; Shen, L; Yuan, A | 1 |
| Boerma, LJ; Chalmers, MJ; Cox, BD; Griffin, PR; Lobo-Ruppert, S; Muccio, DD; Qui, C; Renfrow, MB; Smith, CD; Xia, G | 1 |
| Einar French, L; Guertler, A; Helene Frommherz, L; Kaemmerer, T; Reinholz, M; Stadler, PC | 1 |
2 review(s) available for bexarotene and alitretinoin
| Article | Year |
|---|---|
How retinoids regulate breast cancer cell proliferation and apoptosis.
Topics: Alitretinoin; Anticarcinogenic Agents; Apoptosis; Bexarotene; Breast Neoplasms; Cell Cycle; Cell Division; Female; Fenretinide; Humans; Retinoids; Tetrahydronaphthalenes; Tretinoin | 2004 |
[Advances in studies on selective RXR ligands].
Topics: Alitretinoin; Animals; Antineoplastic Agents; Bexarotene; Humans; Ligands; Neoplasms; Retinoid X Receptors; Retinoids; Structure-Activity Relationship; Tetrahydronaphthalenes; Tretinoin | 2005 |
27 other study(ies) available for bexarotene and alitretinoin
| Article | Year |
|---|---|
Conformational effects on retinoid receptor selectivity. 2. Effects of retinoid bridging group on retinoid X receptor activity and selectivity.
Topics: beta-Galactosidase; Cell Line; Chloramphenicol O-Acetyltransferase; Isotretinoin; Magnetic Resonance Spectroscopy; Protein Conformation; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcription, Genetic | 1995 |
Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers.
Topics: Azepines; Benzoates; Binding, Competitive; Cell Differentiation; Dibenzazepines; Dimerization; Drug Synergism; HL-60 Cells; Humans; Molecular Structure; Protein Binding; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors | 1997 |
Syntheses and structure-activity relationships of novel retinoid X receptor agonists.
Topics: Animals; Cell Line; COS Cells; Cricetinae; Drug Design; Humans; Kinetics; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Quinolones; Receptors, Retinoic Acid; Recombinant Proteins; Retinoid X Receptors; Structure-Activity Relationship; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tretinoin | 1998 |
Synthesis and characterization of a new RXR agonist based on the 6-tert-butyl-1,1-dimethylindanyl structure.
Topics: Butanes; Indans; Models, Molecular; Molecular Structure; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors | 2002 |
Highly twisted adamantyl arotinoids: synthesis, antiproliferative effects and RXR transactivation profiles.
Topics: Adamantane; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Drug Screening Assays, Antitumor; Humans; Models, Chemical; Molecular Structure; Retinoid X Receptors; Retinoids; Stereoisomerism; Structure-Activity Relationship; Transcriptional Activation | 2009 |
Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention.
Topics: Humans; Kruppel-Like Factor 4; Ligands; Molecular Conformation; Neoplasms; Retinoid X Receptors; Retinoids | 2014 |
Methyl substitution of a rexinoid agonist improves potency and reveals site of lipid toxicity.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Bexarotene; Binding Sites; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Crystallography, X-Ray; Fatty Acids, Unsaturated; Female; Humans; Hyperlipidemias; Mammary Neoplasms, Experimental; Models, Molecular; Molecular Structure; Naphthalenes; Rats; Retinoid X Receptor alpha; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes; Transcriptional Activation | 2014 |
Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers.
Topics: Animals; Anticarcinogenic Agents; Binding Sites; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Dyslipidemias; Fatty Acids, Unsaturated; Female; Humans; Mammary Neoplasms, Experimental; Molecular Conformation; Naphthalenes; Rats, Sprague-Dawley; Retinoid X Receptor alpha; Structure-Activity Relationship; Tamoxifen; Triglycerides | 2015 |
DrugBank screening revealed alitretinoin and bexarotene as liver X receptor modulators.
Topics: Alitretinoin; Animals; Bexarotene; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Liver X Receptors; Mice; Tetrahydronaphthalenes; Tretinoin | 2017 |
Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening.
Topics: Binding, Competitive; Fluorescent Dyes; Genes, Reporter; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Ligands; Protein Binding; Retinoid X Receptors; Tetrahydronaphthalenes; Umbelliferones | 2019 |
Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors
Topics: Animals; Animals, Genetically Modified; Heterografts; Humans; Neuroblastoma; Receptors, Calcitriol; Vitamins | 2022 |
Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers.
Topics: Humans; Inflammation; Ligands; Retinoid X Receptors; Skin Neoplasms; Tetrahydronaphthalenes; Tretinoin; Triglycerides | 2022 |
Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells.
Topics: Alitretinoin; Benzoates; Bexarotene; Blotting, Northern; Bronchi; Cell Differentiation; Epithelium; Humans; Isomerism; Luciferases; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Transcription Factor AP-1; Transcription Factors; Transfection; Tretinoin | 1996 |
Potentiation of VD-induced monocytic leukemia cell differentiation by retinoids involves both RAR and RXR signaling pathways.
Topics: Alitretinoin; Animals; Benzoates; Bexarotene; Cell Differentiation; Chromans; COS Cells; HL-60 Cells; Humans; Leukemia, Monocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Molecular Structure; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured; Vitamin D | 1997 |
Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status.
Topics: Alitretinoin; Aminobenzoates; Antineoplastic Agents; Benzoates; Bexarotene; Breast Neoplasms; Cell Division; Chromans; Female; Humans; Nicotinic Acids; Nuclear Proteins; Receptors, Estrogen; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 1997 |
Mechanism of the slow induction of apolipoprotein A-I synthesis by retinoids in cynomolgus hepatocytes: involvement of retinoic acid and retinoid X receptors.
Topics: Alitretinoin; Animals; Apolipoprotein A-I; Benzoates; Bexarotene; Blotting, Northern; Cells, Cultured; Female; Gene Expression Regulation; Liver; Macaca fascicularis; Male; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Time Factors; Transcription Factors; Transcriptional Activation; Tretinoin | 1997 |
Growth inhibition of human in vitro and mouse in vitro and in vivo mammary tumor models by retinoids in comparison with tamoxifen and the RU-486 anti-progestagen.
Topics: Alitretinoin; Animals; Anticarcinogenic Agents; Apoptosis; Benzoates; Bexarotene; Breast Neoplasms; Cell Division; Disease Models, Animal; Female; Fenretinide; Hormone Antagonists; Humans; Mammary Neoplasms, Animal; Mice; Mice, Inbred C57BL; Mifepristone; Retinoids; Tamoxifen; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured | 1998 |
Receptor mechanisms mediating differentiation and proliferation effects of retinoids on neuroblastoma cells.
Topics: Alitretinoin; Bexarotene; Cell Differentiation; Cell Division; Dimerization; Humans; Neuroblastoma; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 2000 |
Where to next with retinoids for cancer therapy?
Topics: Alitretinoin; Antineoplastic Agents; Bexarotene; Humans; Isotretinoin; Neoplasms; Retinoids; Tetrahydronaphthalenes; Tretinoin | 2001 |
[Studies on the structure-activity relationship of retinoids--Hansch analysis and 3D-OSAR studies on specific ligands of retinoid x receptor].
Topics: Alitretinoin; Anticarcinogenic Agents; Antineoplastic Agents; Bexarotene; Molecular Conformation; Quantitative Structure-Activity Relationship; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Structure-Activity Relationship; Tetrahydronaphthalenes; Transcription Factors; Tretinoin | 1998 |
Functional evidence for retinoid X receptor (RXR) as a nonsilent partner in the thyroid hormone receptor/RXR heterodimer.
Topics: Alitretinoin; Anticarcinogenic Agents; Bexarotene; Dimerization; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; HeLa Cells; Herpes Simplex Virus Protein Vmw65; Humans; Ligands; Nuclear Proteins; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Recombinant Fusion Proteins; Retinoid X Receptors; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Triiodothyronine | 2002 |
Immunomodulatory effects of RXR rexinoids: modulation of high-affinity IL-2R expression enhances susceptibility to denileukin diftitox.
Topics: Adjuvants, Immunologic; Alitretinoin; Antineoplastic Agents; B-Lymphocytes; Bexarotene; Diphtheria Toxin; Gene Expression Regulation; Humans; Interleukin-2; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Interleukin-2; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; Retinoids; T-Lymphocytes; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 2002 |
Retinoid signalling and gene expression in neuroblastoma cells: RXR agonist and antagonist effects on CRABP-II and RARbeta expression.
Topics: Alitretinoin; Bexarotene; Dose-Response Relationship, Drug; Gene Expression; Humans; Neuroblastoma; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; RNA, Messenger; Signal Transduction; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 2002 |
Retinoic acid receptors and tissue-transglutaminase mediate short-term effect of retinoic acid on migration and invasion of neuroblastoma SH-SY5Y cells.
Topics: Alitretinoin; Antineoplastic Agents; Bexarotene; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Humans; Kidney; Neoplasm Invasiveness; Neuroblastoma; Protein Glutamine gamma Glutamyltransferase 2; Receptors, Retinoic Acid; Retinoid X Receptors; Signal Transduction; Tetrahydronaphthalenes; Transglutaminases; Tretinoin | 2006 |
RXR agonists inhibit oxidative stress-induced apoptosis in H9c2 rat ventricular cells.
Topics: Alitretinoin; Animals; Apoptosis; Bexarotene; Caspase 3; Cell Survival; Cytochromes c; Heart Ventricles; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondria; Myocytes, Cardiac; Oxidative Stress; Rats; Reactive Oxygen Species; Retinoid X Receptors; Tetrahydronaphthalenes; Tretinoin | 2008 |
Defining the communication between agonist and coactivator binding in the retinoid X receptor α ligand binding domain.
Topics: Alitretinoin; Amino Acid Sequence; Bexarotene; Binding Sites; Crystallography, X-Ray; Fatty Acids, Unsaturated; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Structure; Naphthalenes; Nuclear Receptor Coactivator 2; Protein Binding; Protein Conformation; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Retinoid X Receptor alpha; Tetrahydronaphthalenes; Tretinoin | 2014 |
Alitretinoin in the treatment of cutaneous T-cell lymphoma.
Topics: Adult; Aged; Alitretinoin; Antineoplastic Agents; Bexarotene; Combined Modality Therapy; Disease Progression; Female; Humans; Lymphoma, T-Cell, Cutaneous; Male; Middle Aged; Mycosis Fungoides; PUVA Therapy; Sezary Syndrome; Skin Neoplasms | 2021 |