bexarotene has been researched along with 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chandraratna, RA; Thacher, SM; Vasudevan, J | 1 |
| Dawson, MI; Eckert, RL; Fuchs, E; Hong, WK; Kurie, JM; Lee, HY; Lotan, R; Nesbitt, JC; Walsh, GL | 1 |
| Eichele, G; Lu, HC; Thaller, C | 1 |
| Commes, T; Defacque, H; Marti, J; Piquemal, D; Rochette-Egly, C; Sévilla, C | 1 |
| Allegretto, EA; Chandraratna, RA; Fitzgerald, P; Heyman, RA; Teng, M | 1 |
| Hendriks, HF; Kaptein, A; Kooistra, T; Neele, DM; Princen, HM; Twisk, J | 1 |
| Dallongeville, J; Fruchart, JC; Gervois, P; Kooistra, T; Kosykh, V; Princen, HM; Staels, B; Torra, IP; Vu-Dac, N | 1 |
| Budel, V; Cahen, P; Chaboteaux, C; Darro, F; Decaestecker, C; Kiss, R; Leblond, B; Nogaret, JM; Pétein, M; Pourrias, B; Ramos, C; Schoofs, A; Vianna, A | 1 |
| de Wit, EC; Neele, DM; Princen, HM | 1 |
| Brown, PH; Green, JE; Hilsenbeck, SG; Kim, HT; Kuhn, JG; Lamph, WW; Mohsin, SK; Rodriquez, JL; Wu, K; Xu, XC | 1 |
| Berenz, A; Haugen, BR; Hays, WR; Klopper, JP; Loi, M; Pugazhenthi, U; Said, S; Sharma, V | 1 |
1 review(s) available for bexarotene and 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid
| Article | Year |
|---|---|
Therapeutic applications for ligands of retinoid receptors.
Topics: Animals; Drug Design; Humans; Ligands; Receptors, Retinoic Acid; Retinoids; Structure-Activity Relationship | 2000 |
1 trial(s) available for bexarotene and 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid
| Article | Year |
|---|---|
Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids.
Topics: Adult; Apolipoprotein C-III; Apolipoproteins C; Benzoates; Bexarotene; Carcinoma, Hepatocellular; Cells, Cultured; Dimerization; Double-Blind Method; Gene Expression Regulation; HeLa Cells; Humans; Hypertriglyceridemia; Isotretinoin; Liver; Liver Neoplasms; Male; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
9 other study(ies) available for bexarotene and 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid
| Article | Year |
|---|---|
Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells.
Topics: Alitretinoin; Benzoates; Bexarotene; Blotting, Northern; Bronchi; Cell Differentiation; Epithelium; Humans; Isomerism; Luciferases; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Transcription Factor AP-1; Transcription Factors; Transfection; Tretinoin | 1996 |
Ligand-bound RXR can mediate retinoid signal transduction during embryogenesis.
Topics: Animals; Benzoates; Bexarotene; Central Nervous System; Chick Embryo; Embryonic Induction; Gene Expression Regulation, Developmental; Genes, Homeobox; Homeodomain Proteins; In Situ Hybridization; Ligands; Limb Buds; Morphogenesis; Nerve Tissue Proteins; Otx Transcription Factors; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Trans-Activators; Transcription Factors | 1997 |
Potentiation of VD-induced monocytic leukemia cell differentiation by retinoids involves both RAR and RXR signaling pathways.
Topics: Alitretinoin; Animals; Benzoates; Bexarotene; Cell Differentiation; Chromans; COS Cells; HL-60 Cells; Humans; Leukemia, Monocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Molecular Structure; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured; Vitamin D | 1997 |
Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status.
Topics: Alitretinoin; Aminobenzoates; Antineoplastic Agents; Benzoates; Bexarotene; Breast Neoplasms; Cell Division; Chromans; Female; Humans; Nicotinic Acids; Nuclear Proteins; Receptors, Estrogen; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 1997 |
Mechanism of the slow induction of apolipoprotein A-I synthesis by retinoids in cynomolgus hepatocytes: involvement of retinoic acid and retinoid X receptors.
Topics: Alitretinoin; Animals; Apolipoprotein A-I; Benzoates; Bexarotene; Blotting, Northern; Cells, Cultured; Female; Gene Expression Regulation; Liver; Macaca fascicularis; Male; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Time Factors; Transcription Factors; Transcriptional Activation; Tretinoin | 1997 |
Growth inhibition of human in vitro and mouse in vitro and in vivo mammary tumor models by retinoids in comparison with tamoxifen and the RU-486 anti-progestagen.
Topics: Alitretinoin; Animals; Anticarcinogenic Agents; Apoptosis; Benzoates; Bexarotene; Breast Neoplasms; Cell Division; Disease Models, Animal; Female; Fenretinide; Hormone Antagonists; Humans; Mammary Neoplasms, Animal; Mice; Mice, Inbred C57BL; Mifepristone; Retinoids; Tamoxifen; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured | 1998 |
Inhibition of apolipoprotein(a) synthesis in cynomolgus monkey hepatocytes by retinoids via involvement of the retinoic acid receptor.
Topics: Animals; Antineoplastic Agents; Apolipoproteins A; Benzoates; Bexarotene; Dose-Response Relationship, Drug; Ligands; Lipoproteins; Liver; Macaca fascicularis; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Time Factors; Transcription Factors | 1999 |
Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Benzoates; Bexarotene; Biomarkers, Tumor; Breast Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Growth Inhibitors; Histones; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Sensitivity and Specificity; Tetrahydronaphthalenes; Time Factors; Transcription Factors; Treatment Outcome | 2002 |
Retinoid and thiazolidinedione therapies in melanoma: an analysis of differential response based on nuclear hormone receptor expression.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzoates; Bexarotene; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Ligands; Melanoma; Mice; PPAR gamma; Receptors, Cytoplasmic and Nuclear; Retinoid X Receptors; Retinoids; RNA, Small Interfering; Rosiglitazone; Tetrahydronaphthalenes; Thiazolidinediones; Xenograft Model Antitumor Assays | 2009 |