Page last updated: 2024-08-25

betulinic acid methyl ester and acetazolamide

betulinic acid methyl ester has been researched along with acetazolamide in 1 studies

*Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) [MeSH]

*Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) [MeSH]

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Csuk, R; Heller, L; Lucas, SD; Schwarz, S; Sommerwerk, S1

Other Studies

1 other study(ies) available for betulinic acid methyl ester and acetazolamide

ArticleYear
Sulfamates of methyl triterpenoates are effective and competitive inhibitors of carbonic anhydrase II.
    European journal of medicinal chemistry, 2014, Oct-30, Volume: 86

    Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Mice; Molecular Docking Simulation; Molecular Structure; NIH 3T3 Cells; Structure-Activity Relationship; Sulfonic Acids; Triterpenes

2014