betulinic acid and zidovudine

betulinic acid has been researched along with zidovudine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (25.00)18.2507
2000's3 (18.75)29.6817
2010's8 (50.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Ballas, LM; Chen, IS; Cosentino, LM; Fujioka, T; Janzen, WP; Jiang, JB; Kashiwada, Y; Kilkuskie, RE; Lee, KH1
Chen, CH; Cosentino, LM; Garrett, PE; Hashimoto, F; Kashiwada, Y; Lee, KH1
Chen, CH; Cosentino, LM; Kashiwada, Y; Lee, KH; Shen, JK; Sun, IC; Wang, HK; Yang, LM1
Cosentino, LM; Lee, KH; Shen, JK; Sun, IC; Wang, HK1
Cosentino, LM; Hashimoto, A; Ikeshiro, Y; Kashiwada, Y; Lee, KH; Nagao, T; Okabe, H1
Allaway, GP; Fujioka, T; Ikeshiro, Y; Kashiwada, Y; Kilgore, NR; Lee, KH; Sekiya, M; Wild, CT1
Chen, CH; Dang, Z; Ho, P; Huang, L; Lai, W; Lee, KH; Qian, K1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Lee, KH1
Bori, ID; Chen, CH; Huang, L; Lee, KH; Qian, K1
Cai, L; Jiang, S; Jiang, X; Li, J; Li, X; Liang, G; Liu, K; Lu, L; Na, H; Wang, C; Wang, Q; Xu, X; Yu, F; Zhang, T; Zhang, Z; Zheng, B1
Ba Thi, C; D'hooghe, M; Dang Thi, TA; Doan Duy, T; Kim Tuyet, NT; Pham The, C; Thanh Nguyen, H; Van Nguyen, T1
Arumugam, SR; Badri, KR; He, JJ; Visalli, RJ; Zhang, X; Zhao, H; Ziobrowski, H1
Borkova, L; Hodon, J; Kazakova, A; Pokorny, J; Urban, M1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Chen, CH; Kashiwada, Y; Lee, KH; Morris-Natschke, SL; Qian, K; Takaishi, Y; Xiong, J1

Reviews

2 review(s) available for betulinic acid and zidovudine

ArticleYear
Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach.
    Journal of natural products, 2010, Mar-26, Volume: 73, Issue:3

    Topics: Anti-HIV Agents; Biological Factors; Drug Design; Molecular Structure; Pharmaceutical Preparations; Plants, Medicinal

2010
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research.
    European journal of medicinal chemistry, 2019, Nov-15, Volume: 182

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antiviral Agents; Biomedical Research; Cell Proliferation; Drug Design; Humans; Neoplasms; Triterpenes; Viruses

2019

Other Studies

14 other study(ies) available for betulinic acid and zidovudine

ArticleYear
Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids.
    Journal of natural products, 1994, Volume: 57, Issue:2

    Topics: Antiviral Agents; Betulinic Acid; Cells, Cultured; HIV-1; Humans; Lymphocytes; Pentacyclic Triterpenes; Plants, Medicinal; Protein Kinase C; Triterpenes; Virus Replication

1994
Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents.
    Journal of medicinal chemistry, 1996, Mar-01, Volume: 39, Issue:5

    Topics: Antiviral Agents; Betulinic Acid; Giant Cells; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Pentacyclic Triterpenes; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Triterpenes; Virus Replication

1996
Anti-AIDS agents. 34. Synthesis and structure-activity relationships of betulin derivatives as anti-HIV agents.
    Journal of medicinal chemistry, 1998, Nov-05, Volume: 41, Issue:23

    Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Cell Fusion; Cell Line; Glutarates; HeLa Cells; HIV-1; Humans; Lymphocytes; Mice; Structure-Activity Relationship; Triterpenes; Virus Replication

1998
Anti-AIDS agents. 32. Synthesis and anti-HIV activity of betulin derivatives.
    Bioorganic & medicinal chemistry letters, 1998, May-19, Volume: 8, Issue:10

    Topics: Anti-HIV Agents; Cell Line; Cell Survival; Drug Design; HIV-1; Humans; Lymphocytes; Molecular Structure; Structure-Activity Relationship; Triterpenes

1998
Anti-AIDS agents 38. Anti-HIV activity of 3-O-acyl ursolic acid derivatives.
    Journal of natural products, 2000, Volume: 63, Issue:12

    Topics: Anti-HIV Agents; Cell Line; HIV-1; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Spectrometry, Mass, Fast Atom Bombardment; Triterpenes; Ursolic Acid

2000
3-O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents.
    Bioorganic & medicinal chemistry letters, 2004, Dec-06, Volume: 14, Issue:23

    Topics: Anti-HIV Agents; HIV-1; Humans; Triterpenes

2004
Betulinic acid derivatives as human immunodeficiency virus type 2 (HIV-2) inhibitors.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: Anti-HIV Agents; Betulinic Acid; Cell Line; Dose-Response Relationship, Drug; HIV-1; HIV-2; Humans; Inhibitory Concentration 50; Pentacyclic Triterpenes; Triterpenes

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Anti-AIDS agents 90. novel C-28 modified bevirimat analogues as potent HIV maturation inhibitors.
    Journal of medicinal chemistry, 2012, Sep-27, Volume: 55, Issue:18

    Topics: Anti-HIV Agents; Cell Line; Drug Design; Drug Stability; HIV-1; Humans; Structure-Activity Relationship; Succinates; Triterpenes; Virus Replication

2012
Conjugation of a nonspecific antiviral sapogenin with a specific HIV fusion inhibitor: a promising strategy for discovering new antiviral therapeutics.
    Journal of medicinal chemistry, 2014, Sep-11, Volume: 57, Issue:17

    Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Cell Line, Tumor; Cell Survival; Enfuvirtide; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV-1; Humans; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Protein Structure, Secondary; Sapogenins; Structure-Activity Relationship

2014
Synthesis and cytotoxic evaluation of novel ester-triazole-linked triterpenoid-AZT conjugates.
    Bioorganic & medicinal chemistry letters, 2014, Nov-15, Volume: 24, Issue:22

    Topics: Araliaceae; Cytotoxins; Drug Evaluation, Preclinical; Eleutherococcus; Esters; Hep G2 Cells; Humans; Plant Extracts; Triazoles; Triterpenes; Zidovudine

2014
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2015, Aug-15, Volume: 25, Issue:16

    Topics: Acyclovir; Animals; Antiviral Agents; Betulinic Acid; Chlorocebus aethiops; Herpesvirus 2, Human; HIV Reverse Transcriptase; HIV-1; Humans; Pentacyclic Triterpenes; Triterpenes; Vero Cells; Virus Replication

2015
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Conjugates of betulin derivatives with AZT as potent anti-HIV agents.
    Bioorganic & medicinal chemistry, 2010, Sep-01, Volume: 18, Issue:17

    Topics: Anti-HIV Agents; Betulinic Acid; CD4-Positive T-Lymphocytes; Cell Line; HIV-1; Humans; Pentacyclic Triterpenes; Triterpenes; Zidovudine

2010