betulinic acid and maslinic acid

betulinic acid has been researched along with maslinic acid in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (9.09)29.6817
2010's16 (72.73)24.3611
2020's4 (18.18)2.80

Authors

AuthorsStudies
Alexacou, KM; Cheng, K; Gimisis, T; Hao, J; Hayes, JM; Leonidas, DD; Liu, J; Ni, P; Oikonomakos, NG; Sun, H; Wen, X; Zhang, L; Zhang, P; Zographos, SE1
Chen, J; Chen, L; Cheng, K; Gong, Y; Hao, J; Jiang, H; Li, H; Li, L; Liang, Z; Liu, H; Liu, J; Luo, C; Sun, H; Wen, X; Zhang, L; Zhang, P; Zhang, X; Zheng, M; Zhu, X1
El-Kabbani, O; Endo, S; Hara, A; Iinuma, M; Matsunaga, T; Soda, M; Tajima, K; Takemura, M; Zhao, HT1
Chen, K; Huang, X; Peng, Y; Qiu, Y; Shi, Y; Sun, D; Wang, H; Wang, Q; Xiao, S; Yu, F; Yu, M; Zhang, C; Zhang, L; Zhang, Z; Zhao, C; Zheng, Y; Zhou, D; Zhu, L1
Csuk, R; Pianowski, E; Siewert, B1
Csuk, R; Heller, L; Kuhfs, J; Sommerwerk, S1
Csuk, R; Heller, L; Kerzig, C; Kramell, AE; Sommerwerk, S1
Choi, SU; Kim, CS; Kim, SY; Lee, KR; Oh, J; Subedi, L1
Csuk, R; Fischer, L; Kahnt, M; Sommerwerk, S; Wiemann, J1
Appendino, G; Bellido, ML; Calzado, MA; Caprioglio, D; Cruz, C; Galera, N; Jinénez, C; Minassi, A; Muñoz, E; Prados, ME; Rogati, F1
Andrade, RB; Bougie, D; Boxer, MB; Brimacombe, KR; Brown, LE; Brown, MK; Burns, NZ; Cha, JK; Cheff, DM; Cheng, K; Clardy, J; Clement, JA; Coussens, NP; Crooks, PA; Cuny, GD; Dillon, C; Dorjsuren, D; Eastman, RT; Ganor, J; Garg, NK; Goess, BC; Grossman, RB; Guha, R; Hall, MD; Henderson, MJ; Huang, R; Hughes, CC; Iannotti, MJ; Inglese, J; Itkin, Z; Jadhav, A; Johnston, JN; Joullie, MM; Karavadhi, S; Kearney, SE; Kinghorn, AD; Kingston, DGI; Klumpp-Thomas, C; Krische, MJ; Kwon, O; Lee, TD; Lynch, C; Maimone, TJ; Majumdar, S; Maloney, KN; Mevers, EE; Michael, S; Mohamed, E; Moreno, J; Morrill, LA; Murphy, BT; Nagorny, P; Olson, DE; Overman, LE; Picazo, E; Porco, JA; Ren, T; Rivas, F; Rohde, JM; Ross, SA; Roth, JS; Sakamuru, S; Sarpong, R; Sharma, I; Shaw, JT; Shen, B; Shen, M; Shi, W; Shinn, P; Simeonov, A; Snyder, JK; Stephenson, CRJ; Sun, W; Susick, RB; Tan, DS; Tang, Y; Taylor, RE; Thomson, RJ; Titus, SA; Verano, AL; Vosburg, DA; Wan, KK; Wu, J; Wuest, WM; Xia, M; Xu, Z; Yasgar, A; Zahoránszky-Kőhalmi, G; Zakarian, A; Zhang, Y; Zhang, YQ; Zhao, J; Zhao, T; Zheng, W; Zuo, Z1
Al-Harrasi, A; Csuk, R; Serbian, I; Siewert, B1
Chen, C; Cheng, K; Dai, L; Hu, K; Li, H; Liu, L; Sun, H; Wen, X; Xu, Q; Yuan, H1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Kim, YK; Ryu, SY; Yoon, SK1
Li, GL; Song, CH; Suo, YR; Xia, L; You, JM; Zheng, J1
Bruni, R; Caligiani, A; Malavasi, G; Marseglia, A; Palla, G; Tognolini, M1
Chen, ZH; Liu, QF; Liu, SZ; Wang, HM; Wang, ZZ; Xiao, W; Zhang, RJ; Zhao, WM; Zhao, YW1
He, QQ; Ma, CM; Ma, JN; Yang, L; Zhang, JY1
Chen, G; Hu, N; Li, G; Liu, D; Liu, S; Suo, Y; Wu, H; You, J1
Fang, SQ; Ge, GB; Guan, XQ; He, RJ; Huang, J; Huo, PC; Jia, SN; Wang, L; Xiang, YW; Zhang, F1
Alhadrami, HA; Azhar, EI; Rateb, ME; Sayed, AM; Sharif, AM1

Other Studies

22 other study(ies) available for betulinic acid and maslinic acid

ArticleYear
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Adenosine Monophosphate; Allosteric Site; Animals; Binding Sites; Crystallography, X-Ray; Glycogen Phosphorylase; Hypoglycemic Agents; Kinetics; Models, Molecular; Muscles; Oleanolic Acid; Pentacyclic Triterpenes; Protein Binding; Protein Conformation; Rabbits; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Animals; Enzyme Inhibitors; Glycogen Phosphorylase, Muscle Form; Models, Molecular; Molecular Conformation; Muscle, Skeletal; Pentacyclic Triterpenes; Quantitative Structure-Activity Relationship; Rabbits; Stereoisomerism

2011
Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.
    Journal of natural products, 2011, May-27, Volume: 74, Issue:5

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Antineoplastic Agents, Phytogenic; Drug Resistance, Neoplasm; HeLa Cells; HT29 Cells; Humans; Mitomycin; Models, Molecular; Molecular Structure; Mutation; Oleanolic Acid; Pentacyclic Triterpenes

2011
Development of oleanane-type triterpenes as a new class of HCV entry inhibitors.
    Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11

    Topics: Animals; Antiviral Agents; Cell Line, Tumor; Cytotoxins; HEK293 Cells; Hemolytic Agents; Hepacivirus; Humans; Oleanolic Acid; Rabbits; Structure-Activity Relationship; Virus Internalization

2013
Esters and amides of maslinic acid trigger apoptosis in human tumor cells and alter their mode of action with respect to the substitution pattern at C-28.
    European journal of medicinal chemistry, 2013, Volume: 70

    Topics: Amides; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esters; HT29 Cells; Humans; MCF-7 Cells; Mice; Models, Molecular; Molecular Structure; NIH 3T3 Cells; Structure-Activity Relationship; Triterpenes

2013
Urea derivates of ursolic, oleanolic and maslinic acid induce apoptosis and are selective cytotoxic for several human tumor cell lines.
    European journal of medicinal chemistry, 2016, Aug-25, Volume: 119

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Mice; NIH 3T3 Cells; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2016
Rhodamine B conjugates of triterpenoic acids are cytotoxic mitocans even at nanomolar concentrations.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Animals; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mitochondria; NIH 3T3 Cells; Rhodamines; Structure-Activity Relationship; Triterpenes

2017
Bioactive Triterpenoids from the Twigs of Chaenomeles sinensis.
    Journal of natural products, 2017, 04-28, Volume: 80, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Lipopolysaccharides; Microglia; Molecular Structure; Nerve Growth Factor; Neuroprotective Agents; Nitric Oxide; Plant Components, Aerial; Republic of Korea; Rosaceae; Triterpenes

2017
Transformation of asiatic acid into a mitocanic, bimodal-acting rhodamine B conjugate of nanomolar cytotoxicity.
    European journal of medicinal chemistry, 2018, Nov-05, Volume: 159

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; NIH 3T3 Cells; Pentacyclic Triterpenes; Structure-Activity Relationship

2018
Triterpenoid Hydroxamates as HIF Prolyl Hydrolase Inhibitors.
    Journal of natural products, 2018, 10-26, Volume: 81, Issue:10

    Topics: Enzyme Inhibitors; HEK293 Cells; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; NF-kappa B; Triterpenes

2018
Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.
    ACS central science, 2018, Dec-26, Volume: 4, Issue:12

    Topics:

2018
2-O-(2-chlorobenzoyl) maslinic acid triggers apoptosis in A2780 human ovarian carcinoma cells.
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Mice; Molecular Conformation; NIH 3T3 Cells; Ovarian Neoplasms; Structure-Activity Relationship; Triterpenes

2019
Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Interleukin-6; Liver; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Oleanolic Acid; Pentacyclic Triterpenes; Phosphorylation; Sapogenins; Saponins; Tumor Necrosis Factor-alpha

2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Cytotoxic triterpenes from stem bark of Physocarpus intermedius.
    Planta medica, 2000, Volume: 66, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Humans; Magnetic Resonance Spectroscopy; Oleanolic Acid; Pentacyclic Triterpenes; Plant Stems; Rosales; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2000
Development of a new HPLC method with precolumn fluorescent derivatization for rapid, selective and sensitive detection of triterpenic acids in fruits.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Betulinic Acid; Chromatography, High Pressure Liquid; Fluorescent Dyes; Food Analysis; Fruit; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2011
A simple GC-MS method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients.
    Food chemistry, 2013, Jan-15, Volume: 136, Issue:2

    Topics: Betulinic Acid; Dietary Supplements; Gas Chromatography-Mass Spectrometry; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Plants; Triterpenes; Ursolic Acid

2013
Four new triterpenoids isolated from the resin of Garcinia hanburyi.
    Journal of Asian natural products research, 2014, Volume: 16, Issue:1

    Topics: Betulinic Acid; Garcinia; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pentacyclic Triterpenes; Resins, Plant; Triterpenes; Vietnam

2014
Chemical constituents of gold-red apple and their α-glucosidase inhibitory activities.
    Journal of food science, 2014, Volume: 79, Issue:10

    Topics: alpha-Glucosidases; alpha-Linolenic Acid; Betulinic Acid; Fruit; Glycoside Hydrolase Inhibitors; Magnetic Resonance Spectroscopy; Malus; Oleanolic Acid; Pentacyclic Triterpenes; Spectrometry, Mass, Electrospray Ionization; Triterpenes; Ursolic Acid

2014
Simultaneous determination of six triterpenic acids in some Chinese medicinal herbs using ultrasound-assisted dispersive liquid-liquid microextraction and high-performance liquid chromatography with fluorescence detection.
    Journal of pharmaceutical and biomedical analysis, 2015, Mar-25, Volume: 107

    Topics: Betulinic Acid; Chromatography, High Pressure Liquid; Fluorescence; Limit of Detection; Liquid Phase Microextraction; Medicine, Chinese Traditional; Oleanolic Acid; Pentacyclic Triterpenes; Plants, Medicinal; Solvents; Triterpenes; Ultrasonics; Ursolic Acid

2015
Herb-drug interaction between Styrax and warfarin: Molecular basis and mechanism.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Volume: 77

    Topics: Animals; Anticoagulants; Betulinic Acid; Chromatography, Reverse-Phase; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Herb-Drug Interactions; Humans; Hydroxylation; Male; Microsomes, Liver; Pentacyclic Triterpenes; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Styrax; Tandem Mass Spectrometry; Triterpenes; Warfarin

2020
Olive-Derived Triterpenes Suppress SARS COV-2 Main Protease: A Promising Scaffold for Future Therapeutics.
    Molecules (Basel, Switzerland), 2021, May-01, Volume: 26, Issue:9

    Topics: Antiviral Agents; Betulinic Acid; Coronavirus 3C Proteases; COVID-19; COVID-19 Drug Treatment; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Olea; Pentacyclic Triterpenes; Protease Inhibitors; SARS-CoV-2; Triterpenes; Ursolic Acid

2021