Compounds > betulinic acid

betulinic acid and fluorouracil

betulinic acid has been researched along with fluorouracil in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Bi, Y; Wu, X; Xu, J; Ye, W; Yuan, S; Zhang, L1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chinthakindi, PK; Dangroo, NA; Hamid, A; Khan, I; Koul, S; Majeed, R; Sangwan, PL; Saxena, AK; Sharma, PR; Thota, N1
Alho, DPS; Figueiredo, SAC; Gonçalves, BMF; Leal, AS; Mendes, VIS; Salvador, JAR; Silvestre, SM; Valdeira, AS1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Choi, CH; Han, HK; Han, SI; Jung, GR; Kim, KJ; Lee, TB; Lim, SC1
Goh, TB; Koh, RY; Mansor, SM; Mordi, MN1
Dou, YC; Liu, JB; Wang, YJ1

Reviews

1 review(s) available for betulinic acid and fluorouracil

ArticleYear
Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Humans; Indolequinones; Neoplasms; Oleanolic Acid; Structure-Activity Relationship; Triterpenes

2017

Other Studies

7 other study(ies) available for betulinic acid and fluorouracil

ArticleYear
Synthesis and cytotoxic activity of 17-carboxylic acid modified 23-hydroxy betulinic acid ester derivatives.
    Bioorganic & medicinal chemistry letters, 2007, Mar-01, Volume: 17, Issue:5

    Topics: Animals; Antineoplastic Agents; Betulinic Acid; Carboxylic Acids; Cell Line, Tumor; Esters; Humans; Mice; Neoplasms, Experimental; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes; Tumor Burden

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Synthesis of 3-O-propargylated betulinic acid and its 1,2,3-triazoles as potential apoptotic agents.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Apoptosis; Betulinic Acid; Cell Line, Tumor; Cell Movement; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; HL-60 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Membrane Potential, Mitochondrial; Models, Chemical; Molecular Structure; Pentacyclic Triterpenes; Structure-Activity Relationship; Triazoles; Triterpenes

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Effect of betulinic acid on anticancer drug-resistant colon cancer cells.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 101, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; bcl-2-Associated X Protein; bcl-Associated Death Protein; Betulinic Acid; Camptothecin; Caspases; Cell Death; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; Irinotecan; Mitochondria; Multidrug Resistance-Associated Proteins; Organoplatinum Compounds; Oxaliplatin; Pentacyclic Triterpenes; Triterpenes

2007
Antioxidant value and antiproliferative efficacy of mitragynine and a silane reduced analogue.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:14

    Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antioxidants; Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Colonic Neoplasms; Fluorouracil; HCT116 Cells; Humans; Mice; Oxidative Stress; Pentacyclic Triterpenes; Plant Preparations; Secologanin Tryptamine Alkaloids; Silanes; Triterpenes

2014
Sequential treatment with betulinic acid followed by 5-fluorouracil shows synergistic cytotoxic activity in ovarian cancer cells.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Betulinic Acid; Blotting, Western; Carcinoma; Cell Line, Tumor; Drug Synergism; Female; Flow Cytometry; Fluorouracil; Hedgehog Proteins; Humans; Ovarian Neoplasms; Pentacyclic Triterpenes; Triterpenes

2015