betulinic acid and bevirimat

betulinic acid has been researched along with bevirimat in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's7 (46.67)29.6817
2010's5 (33.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Chen, CH; Cosentino, LM; Garrett, PE; Hashimoto, F; Kashiwada, Y; Lee, KH1
Chen, CH; Cosentino, LM; Kashiwada, Y; Lee, KH; Shen, JK; Sun, IC; Wang, HK; Yang, LM1
Cosentino, LM; Hashimoto, A; Ikeshiro, Y; Kashiwada, Y; Lee, KH; Nagao, T; Okabe, H1
Allaway, GP; Fujioka, T; Ikeshiro, Y; Kashiwada, Y; Kilgore, NR; Lee, KH; Sekiya, M; Wild, CT1
Lee, KH; Nakagawa-Goto, K; Taniguchi, M; Tokuda, H; Yamada, K1
Chen, CH; Dang, Z; Ho, P; Huang, L; Lai, W; Lee, KH; Qian, K1
Lee, KH1
Bori, ID; Chen, CH; Huang, L; Lee, KH; Qian, K1
Bouaziz, S; Briant, L; Chazal, N; Coric, P; Gay, B; Royer, J; Souquet, F; Turcaud, S1
Talele, TT1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Goto, T; Gotoh, K; Kanamoto, T; Kanbara, K; Kashiwada, Y; Nakashima, H; Sano, K; Yoshimori, M1
Stix, G1
Chen, CH; Ho, P; Huang, L1
Ablan, S; Durell, SR; Freed, EO; Gaur, R; Ghimire, D; Kaplan, JA; Kuruppu, N; Mandt, R; Martin, DE; Nitz, TJ; Pham, P; Timilsina, U; Urano, E; Wild, CT1

Reviews

2 review(s) available for betulinic acid and bevirimat

ArticleYear
Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach.
    Journal of natural products, 2010, Mar-26, Volume: 73, Issue:3

    Topics: Anti-HIV Agents; Biological Factors; Drug Design; Molecular Structure; Pharmaceutical Preparations; Plants, Medicinal

2010
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.
    Journal of medicinal chemistry, 2018, 03-22, Volume: 61, Issue:6

    Topics: Animals; Biological Products; Chemistry, Pharmaceutical; Humans

2018

Other Studies

13 other study(ies) available for betulinic acid and bevirimat

ArticleYear
Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents.
    Journal of medicinal chemistry, 1996, Mar-01, Volume: 39, Issue:5

    Topics: Antiviral Agents; Betulinic Acid; Giant Cells; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Pentacyclic Triterpenes; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Triterpenes; Virus Replication

1996
Anti-AIDS agents. 34. Synthesis and structure-activity relationships of betulin derivatives as anti-HIV agents.
    Journal of medicinal chemistry, 1998, Nov-05, Volume: 41, Issue:23

    Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Cell Fusion; Cell Line; Glutarates; HeLa Cells; HIV-1; Humans; Lymphocytes; Mice; Structure-Activity Relationship; Triterpenes; Virus Replication

1998
Anti-AIDS agents 38. Anti-HIV activity of 3-O-acyl ursolic acid derivatives.
    Journal of natural products, 2000, Volume: 63, Issue:12

    Topics: Anti-HIV Agents; Cell Line; HIV-1; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Spectrometry, Mass, Fast Atom Bombardment; Triterpenes; Ursolic Acid

2000
3-O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents.
    Bioorganic & medicinal chemistry letters, 2004, Dec-06, Volume: 14, Issue:23

    Topics: Anti-HIV Agents; HIV-1; Humans; Triterpenes

2004
Cancer preventive agents 9. Betulinic acid derivatives as potent cancer chemopreventive agents.
    Bioorganic & medicinal chemistry letters, 2009, Jul-01, Volume: 19, Issue:13

    Topics: Anticarcinogenic Agents; Antigens, Viral; Betulinic Acid; Cell Line, Tumor; Esterification; Humans; Pentacyclic Triterpenes; Tetradecanoylphorbol Acetate; Triterpenes

2009
Betulinic acid derivatives as human immunodeficiency virus type 2 (HIV-2) inhibitors.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: Anti-HIV Agents; Betulinic Acid; Cell Line; Dose-Response Relationship, Drug; HIV-1; HIV-2; Humans; Inhibitory Concentration 50; Pentacyclic Triterpenes; Triterpenes

2009
Anti-AIDS agents 90. novel C-28 modified bevirimat analogues as potent HIV maturation inhibitors.
    Journal of medicinal chemistry, 2012, Sep-27, Volume: 55, Issue:18

    Topics: Anti-HIV Agents; Cell Line; Drug Design; Drug Stability; HIV-1; Humans; Structure-Activity Relationship; Succinates; Triterpenes; Virus Replication

2012
Synthesis and biological evaluation of a new derivative of bevirimat that targets the Gag CA-SP1 cleavage site.
    European journal of medicinal chemistry, 2013, Volume: 62

    Topics: Anti-HIV Agents; Binding Sites; Dose-Response Relationship, Drug; gag Gene Products, Human Immunodeficiency Virus; HEK293 Cells; HIV-1; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship; Succinates; Triterpenes

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Anti-human immunodeficiency virus activity of YK-FH312 (a betulinic acid derivative), a novel compound blocking viral maturation.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:4

    Topics: Anti-HIV Agents; Betulinic Acid; Cell Fusion; Formazans; Giant Cells; HIV-1; Humans; Microbial Sensitivity Tests; Pentacyclic Triterpenes; Tetrazolium Salts; Time Factors; Triterpenes; Tumor Cells, Cultured; Viral Proteins; Virion

2001
A new assault on HIV.
    Scientific American, 2006, Volume: 294, Issue:6

    Topics: Anti-HIV Agents; Betulinic Acid; Clinical Trials as Topic; Drug Interactions; Drug Resistance, Viral; Drugs, Chinese Herbal; Gene Products, gag; HIV; Humans; Pentacyclic Triterpenes; Succinates; Triterpenes; Virus Cultivation

2006
Activation and inhibition of the proteasome by betulinic acid and its derivatives.
    FEBS letters, 2007, Oct-16, Volume: 581, Issue:25

    Topics: Betulinic Acid; Cell Line, Tumor; Chymotrypsin; Enzyme Activation; Humans; Pentacyclic Triterpenes; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Succinates; Triterpenes

2007
Resistance to Second-Generation HIV-1 Maturation Inhibitors.
    Journal of virology, 2019, 03-15, Volume: 93, Issue:6

    Topics: Anti-HIV Agents; Betulinic Acid; Capsid; Capsid Proteins; Cell Line; Drug Resistance, Viral; gag Gene Products, Human Immunodeficiency Virus; HIV Seropositivity; HIV-1; Humans; Jurkat Cells; Mutation; Pentacyclic Triterpenes; Succinates; Triterpenes; Virion; Virus Assembly; Virus Replication

2019