betulinic acid has been researched along with betulonic acid in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.70) | 18.2507 |
| 2000's | 17 (45.95) | 29.6817 |
| 2010's | 16 (43.24) | 24.3611 |
| 2020's | 3 (8.11) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, DS; Pezzuto, JM; Pisha, E | 1 |
| Chatterjee, P; Hamann, MT; Kouzi, SA; Pezzuto, JM | 1 |
| Cuong, NM; Fong, HH; Hoang, VD; Hung, NV; Pezzuto, JM; Soejarto, DD; Tan, GT; Zhang, HJ | 1 |
| Baltina, LA; Boreko, EI; Flekhter, OB; Nigmatullina, LR; Nikolaeva, SN; Pavlova, NI; Savinova, OV; Tolstikov, GA | 1 |
| Burman, AC; Jaggi, M; Mukherjee, R; Rajendran, P; Siddiqui, MJ; Srivastava, SK; Vardhan, A | 3 |
| Hajduch, M; Klinot, J; Korinkova, G; Sarek, J; Urban, M | 1 |
| Hajduch, M; Kvasnica, M; Sarek, J; Tislerova, I; Urban, M | 1 |
| Chang, ST; Chien, SC; Hou, CC; Hsiao, PW; Jan, JT; Kuo, CJ; Kuo, YH; Lee, CK; Lee, SS; Liang, PH; Liu, HG; Shyur, LF; Wang, SY; Wen, CC; Yang, NS | 1 |
| Ahmad, KF; Badria, FA; Bar, FM; El Sayed, KA; Elnagar, AY; Khanfar, MA; Liu, H; Raisch, KP; Sylvester, PW; Zaghloul, AM | 1 |
| Ahola, T; Alakurtti, S; Pohjala, L; Tammela, P; Yli-Kauhaluoma, J | 1 |
| Auwerx, J; Boudjelal, G; Genet, C; Lobstein, A; Saladin, R; Schmidt, C; Schoonjans, K; Souchet, M; Strehle, A; Wagner, A | 1 |
| Dräger, B; Kalbitz, J; Kaluderović, GN; Kommera, H; Paschke, R | 1 |
| Alakurtti, S; Čapková, K; Janda, KD; Shoemaker, CB; Šilhár, P; Xiaochuan, F; Yli-Kauhaluoma, J | 1 |
| Dzubak, P; Hajduch, M; Sarek, J; Urban, M; Vlk, M | 1 |
| Baratto, LC; Oliveira, BH; Paschke, R; Pereira Netto, AB; Pimentel, IC; Porsani, MV | 1 |
| Arumugam, SR; Badri, KR; He, JJ; Visalli, RJ; Zhang, X; Zhao, H; Ziobrowski, H | 1 |
| Csuk, R; Heller, L; Kluge, R; Perl, V; Ströhl, D; Wiemann, J | 1 |
| Alakurtti, S; Haavikko, R; Hämäläinen, M; Laavola, M; Leppänen, T; Moilanen, E; Moreira, VM; Nieminen, R; Yli-Kauhaluoma, J | 1 |
| Gupta, N; Qayum, A; Rath, SK; Sangwan, PL; Singh, J; Singh, S | 1 |
| García-Cámara, I; Moo-Puc, RE; Peraza-Sánchez, SR; Torres-Tapia, LW; Valencia-Chan, LS | 1 |
| Csuk, R; Deigner, HP; Heise, NV; Hoenke, S; Kahnt, M | 1 |
| Miao, Z; Wang, C; Wang, Y; Wu, Y; Ye, S; Zhang, H; Zhang, Y; Zhu, Y | 1 |
| Kim, DS; Kim, JY; Koo, HM | 1 |
| Chen, B; Mi, HM; Wu, YT; Xing, WX; Yang, GJ; Zhu, M | 1 |
| Boreko, EI; Flekhter, OB; Nikolaeva, SN; Pavlova, NI; Savinova, OV | 1 |
| Choi, SU; Choi, SZ; Lee, KR; Yang, MC | 1 |
| Tanaka, R; Wada, S | 1 |
| Bastos, DZ; de Jesus, DA; de Oliveira, BH; Pimentel, IC | 1 |
| Alakurtti, S; Bergström, P; Jaffe, CL; Sacerdoti-Sierra, N; Yli-Kauhaluoma, J | 1 |
| Li, GL; Song, CH; Suo, YR; Xia, L; You, JM; Zheng, J | 1 |
| Chen, G; Hu, N; Li, G; Liu, D; Liu, S; Suo, Y; Wu, H; You, J | 1 |
| Huang, GQ; Li, B; Lu, RM; Wei, JH; Zhong, ZG | 1 |
| Baranovsky, AV; Khlebnicova, TS; Kumpiņš, V; Lakhvich, FA; Mieriņa, I; Peipiņš, U; Piven, YA; Rāviņa, I; Rijkure, I; Shishkina, SV; Tetere, Z; Turks, M; Zicāne, D | 1 |
| Levdansky, VA; Maksimov, NG; Rubaylo, AI; Sursyakova, VV | 1 |
| Abdullin, TI; Grigor Eva, LR; Khozyainova, SA; Mironov, VF; Nemtarev, AV; Salikhova, TI; Tsepaeva, OV | 1 |
37 other study(ies) available for betulinic acid and betulonic acid
| Article | Year |
|---|---|
Synthesis of betulinic acid derivatives with activity against human melanoma.
Topics: Antineoplastic Agents; Betulinic Acid; Carcinoma, Squamous Cell; Drug Screening Assays, Antitumor; Humans; Hydrogen Bonding; Melanoma; Mouth Neoplasms; Pentacyclic Triterpenes; Triterpenes | 1998 |
Microbial transformations of the antimelanoma agent betulinic acid.
Topics: Antineoplastic Agents; Bacillus megaterium; Betulinic Acid; Biotransformation; Cunninghamella; Melanoma; Pentacyclic Triterpenes; Spectrum Analysis; Triterpenes | 2000 |
Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea.
Topics: Anti-HIV Agents; Chlorophyll; Ericales; Humans; Inhibitory Concentration 50; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Osteosarcoma; Plant Leaves; Plant Stems; Plants, Medicinal; Sesquiterpenes; Stereoisomerism; Triterpenes; Tumor Cells, Cultured; Vietnam | 2003 |
Lupane triterpenes and derivatives with antiviral activity.
Topics: Antiviral Agents; Microbial Sensitivity Tests; Triterpenes | 2003 |
Betulinic acid and its derivatives as anti-angiogenic agents.
Topics: Angiogenesis Inhibitors; Betulinic Acid; Cell Line, Tumor; Humans; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2004 |
Synthesis of 3-O-acyl/3-benzylidene/3-hydrazone/3-hydrazine/17-carboxyacryloyl ester derivatives of betulinic acid as anti-angiogenic agents.
Topics: Angiogenesis Inhibitors; Benzylidene Compounds; Betulinic Acid; Cell Line, Tumor; HT29 Cells; Humans; Pentacyclic Triterpenes; Triterpenes | 2004 |
Synthesis and cytotoxic activity of 3-O-acyl/3-hydrazine /2-bromo/20,29-dibromo betulinic acid derivatives.
Topics: Antineoplastic Agents; Betulinic Acid; Cell Line; Cell Line, Tumor; Cell Survival; Humans; Hydrazines; Jurkat Cells; Models, Molecular; Molecular Conformation; Pentacyclic Triterpenes; Triterpenes | 2004 |
Synthesis of A-seco derivatives of betulinic acid with cytotoxic activity.
Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Combinatorial Chemistry Techniques; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured | 2004 |
Triterpenoid pyrazines and benzopyrazines with cytotoxic activity.
Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Leukemia, T-Cell; Molecular Structure; Pentacyclic Triterpenes; Pyrazines; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured | 2007 |
Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus.
Topics: Animals; Betulinic Acid; Cell Proliferation; Chlorocebus aethiops; Coronavirus 3C Proteases; Cysteine Endopeptidases; Lignans; Models, Molecular; Pentacyclic Triterpenes; Plants, Medicinal; Severe acute respiratory syndrome-related coronavirus; Structure-Activity Relationship; Terpenes; Triterpenes; Vero Cells; Viral Proteins; Virus Replication | 2007 |
Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors.
Topics: Betulinic Acid; DNA; Humans; Models, Chemical; Molecular Structure; Pentacyclic Triterpenes; Topoisomerase I Inhibitors; Triterpenes | 2009 |
Betulin-derived compounds as inhibitors of alphavirus replication.
Topics: Betulinic Acid; Guanosine; Molecular Structure; Pentacyclic Triterpenes; Semliki forest virus; Sindbis Virus; Triterpenes; Virus Replication | 2009 |
Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.
Topics: 3T3-L1 Cells; Animals; Betulinic Acid; CHO Cells; Cricetinae; Cricetulus; Male; Mice; Mice, Inbred C57BL; Molecular Conformation; Pentacyclic Triterpenes; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship; Triterpenes | 2010 |
Small structural changes of pentacyclic lupane type triterpenoid derivatives lead to significant differences in their anticancer properties.
Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cell Line, Tumor; Humans; Kinetics; Spectrum Analysis; Structure-Activity Relationship; Triterpenes | 2010 |
Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease.
Topics: Animals; Botulinum Toxins; Botulinum Toxins, Type A; Neurons; Protease Inhibitors; Rats; Small Molecule Libraries; Structure-Activity Relationship; Succinates; Triterpenes | 2011 |
Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid.
Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Cell Line, Tumor; Crystallography, X-Ray; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2012 |
Preparation of betulinic acid derivatives by chemical and biotransformation methods and determination of cytotoxicity against selected cancer cell lines.
Topics: Apoptosis; Betulinic Acid; Cell Line, Tumor; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Hydrazones; Inhibitory Concentration 50; Molecular Structure; Pentacyclic Triterpenes; Triterpenes | 2013 |
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Topics: Acyclovir; Animals; Antiviral Agents; Betulinic Acid; Chlorocebus aethiops; Herpesvirus 2, Human; HIV Reverse Transcriptase; HIV-1; Humans; Pentacyclic Triterpenes; Triterpenes; Vero Cells; Virus Replication | 2015 |
Betulinic acid derived hydroxamates and betulin derived carbamates are interesting scaffolds for the synthesis of novel cytotoxic compounds.
Topics: Animals; Antineoplastic Agents; Betulinic Acid; Carbamates; Cell Line, Tumor; Cell Proliferation; Cytotoxins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Hydroxamic Acids; Mice; Molecular Structure; NIH 3T3 Cells; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2015 |
Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo.
Topics: Animals; Anti-Inflammatory Agents; Betula; Betulinic Acid; Carrageenan; Chemokine CCL2; Cyclooxygenase 2; Cytokines; Dinoprostone; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Mice; Molecular Structure; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Pentacyclic Triterpenes; Triterpenes | 2016 |
Synthesis of novel benzylidene analogues of betulinic acid as potent cytotoxic agents.
Topics: Antineoplastic Agents; Benzylidene Compounds; Cell Line, Tumor; Cell Proliferation; Cytotoxins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship | 2017 |
Lupane-Type Triterpenes of Phoradendron vernicosum.
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; HeLa Cells; Humans; KB Cells; MCF-7 Cells; Mexico; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phoradendron; Plant Components, Aerial; Plant Extracts; Plant Leaves; Triterpenes | 2017 |
Betulinic acid derived amides are highly cytotoxic, apoptotic and selective.
Topics: Amides; Animals; Antineoplastic Agents; Apoptosis; Betulinic Acid; Cell Line, Tumor; Drug Interactions; Drug Screening Assays, Antitumor; Humans; Mice; NIH 3T3 Cells; Pentacyclic Triterpenes | 2020 |
Discovery and optimization of betulinic acid derivatives as novel potent CD73 inhibitors.
Topics: 5'-Nucleotidase; Adenosine; Betulinic Acid; Humans; Immunotherapy; Neoplasms; Pentacyclic Triterpenes | 2022 |
Development of C-20 modified betulinic acid derivatives as antitumor agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Betulinic Acid; Drug Screening Assays, Antitumor; Humans; Male; Melanoma; Oleanolic Acid; Pentacyclic Triterpenes; Prostatic Neoplasms; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured | 2001 |
[Studies on chemical constituents in fruit of Eucalyptus globulus].
Topics: Betulinic Acid; Eucalyptus; Fruit; Oleanolic Acid; Pentacyclic Triterpenes; Plants, Medicinal; Triterpenes | 2002 |
Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses.
Topics: Antiviral Agents; Betulinic Acid; Dose-Response Relationship, Drug; Echovirus 6, Human; Herpesvirus 1, Human; Humans; Influenza A virus; Microbial Sensitivity Tests; Oleanolic Acid; Pentacyclic Triterpenes; Phytotherapy; Plant Bark; Plant Extracts; Triterpenes; Tumor Cells, Cultured; Viral Envelope Proteins | 2003 |
Cytotoxic terpenes and lignans from the roots of Ainsliaea acerifolia.
Topics: Antineoplastic Agents, Phytogenic; Asteraceae; Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Humans; Inhibitory Concentration 50; Lignans; Oleanolic Acid; Pentacyclic Triterpenes; Plant Roots; Sesquiterpenes; Sesquiterpenes, Guaiane; Triterpenes | 2006 |
Betulinic acid and its derivatives, potent DNA topoisomerase II inhibitors, from the bark of Bischofia javanica.
Topics: Betulinic Acid; Coumarins; Euphorbiaceae; Humans; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Bark; Topoisomerase II Inhibitors; Triterpenes | 2005 |
Biotransformation of betulinic and betulonic acids by fungi.
Topics: Ascomycota; Betulinic Acid; Biotransformation; Colletotrichum; Fungi; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes | 2007 |
Anti-leishmanial activity of betulin derivatives.
Topics: Animals; Antiprotozoal Agents; Betulinic Acid; Cell Line; Cell Survival; Humans; Leishmania donovani; Macrophages; Mice; Oleanolic Acid; Oxidation-Reduction; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2010 |
Development of a new HPLC method with precolumn fluorescent derivatization for rapid, selective and sensitive detection of triterpenic acids in fruits.
Topics: Betulinic Acid; Chromatography, High Pressure Liquid; Fluorescent Dyes; Food Analysis; Fruit; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid | 2011 |
Simultaneous determination of six triterpenic acids in some Chinese medicinal herbs using ultrasound-assisted dispersive liquid-liquid microextraction and high-performance liquid chromatography with fluorescence detection.
Topics: Betulinic Acid; Chromatography, High Pressure Liquid; Fluorescence; Limit of Detection; Liquid Phase Microextraction; Medicine, Chinese Traditional; Oleanolic Acid; Pentacyclic Triterpenes; Plants, Medicinal; Solvents; Triterpenes; Ultrasonics; Ursolic Acid | 2015 |
[Study on Chemical Composition of Phyllanthus emblica].
Topics: Betulinic Acid; Gallic Acid; Oleanolic Acid; Pentacyclic Triterpenes; Phyllanthus emblica; Phytochemicals; Plants, Medicinal; Quercetin; Rutin; Triterpenes; Ursolic Acid | 2015 |
Synthesis of novel lupane triterpenoid-indazolone hybrids with oxime ester linkage.
Topics: Betulinic Acid; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2017 |
Combination of phase-solubility method and capillary zone electrophoresis to determine binding constants of cyclodextrins with practically water-insoluble compounds.
Topics: Betulinic Acid; Cyclodextrins; Electrolytes; Electrophoresis, Capillary; Oleanolic Acid; Pentacyclic Triterpenes; Solubility; Temperature; Triterpenes; Water | 2018 |
Synthesis, Anticancer, and Antibacterial Activity of Betulinic and Betulonic Acid C-28-Triphenylphosphonium Conjugates with Variable Alkyl Linker Length.
Topics: Alkanes; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Betulinic Acid; Cytosol; Drug Design; Esters; Fluoresceins; Fluorescent Dyes; Gram-Positive Bacteria; Halogens; Humans; Mitochondria; Molecular Structure; Oleanolic Acid; Organophosphorus Compounds; PC-3 Cells; Pentacyclic Triterpenes; Structure-Activity Relationship; Superoxides; Triterpenes | 2020 |