betulin has been researched along with betulonic acid in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, DS; Pezzuto, JM; Pisha, E | 1 |
| Cuong, NM; Fong, HH; Hoang, VD; Hung, NV; Pezzuto, JM; Soejarto, DD; Tan, GT; Zhang, HJ | 1 |
| Hajduch, M; Kvasnica, M; Sarek, J; Tislerova, I; Urban, M | 1 |
| Ahola, T; Alakurtti, S; Pohjala, L; Tammela, P; Yli-Kauhaluoma, J | 1 |
| Auwerx, J; Boudjelal, G; Genet, C; Lobstein, A; Saladin, R; Schmidt, C; Schoonjans, K; Souchet, M; Strehle, A; Wagner, A | 1 |
| Dzubak, P; Hajduch, M; Sarek, J; Urban, M; Vlk, M | 1 |
| Barthel, A; Csuk, R; Nitsche, C; Siewert, B; Stark, S | 1 |
| Arumugam, SR; Badri, KR; He, JJ; Visalli, RJ; Zhang, X; Zhao, H; Ziobrowski, H | 1 |
| Csuk, R; Heller, L; Kluge, R; Perl, V; Ströhl, D; Wiemann, J | 1 |
| Alakurtti, S; Haavikko, R; Hämäläinen, M; Laavola, M; Leppänen, T; Moilanen, E; Moreira, VM; Nieminen, R; Yli-Kauhaluoma, J | 1 |
| Borkova, L; Burianova, R; Dzubak, P; Gurska, S; Hajduch, M; Popa, I; Sarek, J; Urban, M | 1 |
| García-Cámara, I; Moo-Puc, RE; Peraza-Sánchez, SR; Torres-Tapia, LW; Valencia-Chan, LS | 1 |
| Dehaen, W; Dijkman, R; Jochmans, D; Krasniqi, B; Naesens, L; Nguyen, T; Stevaert, A; Thiel, V; Thomas, J; Van Loy, B; Vandeput, J; Voet, A | 1 |
| Miao, Z; Wang, C; Wang, Y; Wu, Y; Ye, S; Zhang, H; Zhang, Y; Zhu, Y | 1 |
| Akihisa, T; Ichiishi, E; Kimura, Y; Nakahara, T; Nishino, H; Takamine, Y; Tokuda, H; Ukiya, M; Yokochi, T; Yoshizumi, K | 1 |
| Boreko, EI; Flekhter, OB; Nikolaeva, SN; Pavlova, NI; Savinova, OV | 1 |
| Alakurtti, S; Bergström, P; Jaffe, CL; Sacerdoti-Sierra, N; Yli-Kauhaluoma, J | 1 |
| Burlova, I; Gulenova, M; Kiseleva, T; Kislitsin, CA; Klabukova, I; Melnikova, N; Tanaseichuk, B; Vasin, V | 1 |
| Belosludtsev, KN; Dubinin, MV; Gudkov, SV; Ilzorkina, AI; Ishmuratov, GY; Khoroshavina, EI; Mikheeva, IB; Penkov, NV; Semenova, AA; Sharapov, VA; Vydrina, VA; Yashin, VA | 1 |
19 other study(ies) available for betulin and betulonic acid
| Article | Year |
|---|---|
Synthesis of betulinic acid derivatives with activity against human melanoma.
Topics: Antineoplastic Agents; Betulinic Acid; Carcinoma, Squamous Cell; Drug Screening Assays, Antitumor; Humans; Hydrogen Bonding; Melanoma; Mouth Neoplasms; Pentacyclic Triterpenes; Triterpenes | 1998 |
Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea.
Topics: Anti-HIV Agents; Chlorophyll; Ericales; Humans; Inhibitory Concentration 50; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Osteosarcoma; Plant Leaves; Plant Stems; Plants, Medicinal; Sesquiterpenes; Stereoisomerism; Triterpenes; Tumor Cells, Cultured; Vietnam | 2003 |
Triterpenoid pyrazines and benzopyrazines with cytotoxic activity.
Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Leukemia, T-Cell; Molecular Structure; Pentacyclic Triterpenes; Pyrazines; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured | 2007 |
Betulin-derived compounds as inhibitors of alphavirus replication.
Topics: Betulinic Acid; Guanosine; Molecular Structure; Pentacyclic Triterpenes; Semliki forest virus; Sindbis Virus; Triterpenes; Virus Replication | 2009 |
Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.
Topics: 3T3-L1 Cells; Animals; Betulinic Acid; CHO Cells; Cricetinae; Cricetulus; Male; Mice; Mice, Inbred C57BL; Molecular Conformation; Pentacyclic Triterpenes; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship; Triterpenes | 2010 |
Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid.
Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Cell Line, Tumor; Crystallography, X-Ray; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2012 |
Alkylidene branched lupane derivatives: synthesis and antitumor activity.
Topics: Alkenes; Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Hydroxides; Inhibitory Concentration 50; Oxidation-Reduction; Triterpenes | 2012 |
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Topics: Acyclovir; Animals; Antiviral Agents; Betulinic Acid; Chlorocebus aethiops; Herpesvirus 2, Human; HIV Reverse Transcriptase; HIV-1; Humans; Pentacyclic Triterpenes; Triterpenes; Vero Cells; Virus Replication | 2015 |
Betulinic acid derived hydroxamates and betulin derived carbamates are interesting scaffolds for the synthesis of novel cytotoxic compounds.
Topics: Animals; Antineoplastic Agents; Betulinic Acid; Carbamates; Cell Line, Tumor; Cell Proliferation; Cytotoxins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Hydroxamic Acids; Mice; Molecular Structure; NIH 3T3 Cells; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2015 |
Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo.
Topics: Animals; Anti-Inflammatory Agents; Betula; Betulinic Acid; Carrageenan; Chemokine CCL2; Cyclooxygenase 2; Cytokines; Dinoprostone; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Mice; Molecular Structure; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Pentacyclic Triterpenes; Triterpenes | 2016 |
Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells.
Topics: Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Cytotoxins; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Nucleic Acids; Oleanolic Acid; Triterpenes | 2016 |
Lupane-Type Triterpenes of Phoradendron vernicosum.
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; HeLa Cells; Humans; KB Cells; MCF-7 Cells; Mexico; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phoradendron; Plant Components, Aerial; Plant Extracts; Plant Leaves; Triterpenes | 2017 |
Betulonic Acid Derivatives Interfering with Human Coronavirus 229E Replication via the nsp15 Endoribonuclease.
Topics: Antiviral Agents; Cell Line; Coronavirus 229E, Human; Dose-Response Relationship, Drug; Endoribonucleases; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Models, Molecular; Oleanolic Acid; Viral Nonstructural Proteins; Virus Replication | 2021 |
Discovery and optimization of betulinic acid derivatives as novel potent CD73 inhibitors.
Topics: 5'-Nucleotidase; Adenosine; Betulinic Acid; Humans; Immunotherapy; Neoplasms; Pentacyclic Triterpenes | 2022 |
Microbial transformations of two lupane-type triterpenes and anti-tumor-promoting effects of the transformation products.
Topics: Antigens, Viral; Antineoplastic Agents, Phytogenic; Biotransformation; Drug Screening Assays, Antitumor; Fungi; Humans; Japan; Lymphoma, B-Cell; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Stereoisomerism; Tetradecanoylphorbol Acetate; Triterpenes | 2002 |
Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses.
Topics: Antiviral Agents; Betulinic Acid; Dose-Response Relationship, Drug; Echovirus 6, Human; Herpesvirus 1, Human; Humans; Influenza A virus; Microbial Sensitivity Tests; Oleanolic Acid; Pentacyclic Triterpenes; Phytotherapy; Plant Bark; Plant Extracts; Triterpenes; Tumor Cells, Cultured; Viral Envelope Proteins | 2003 |
Anti-leishmanial activity of betulin derivatives.
Topics: Animals; Antiprotozoal Agents; Betulinic Acid; Cell Line; Cell Survival; Humans; Leishmania donovani; Macrophages; Mice; Oleanolic Acid; Oxidation-Reduction; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2010 |
A practical synthesis of betulonic acid using selective oxidation of betulin on aluminium solid support.
Topics: Aluminum; Oleanolic Acid; Oxidation-Reduction; Solid-Phase Synthesis Techniques; Triterpenes | 2012 |
Effect of betulin and betulonic acid on isolated rat liver mitochondria and liposomes.
Topics: Animals; Electron Transport; Energy Metabolism; Hydrogen Peroxide; Liposomes; Membrane Potential, Mitochondrial; Mitochondria, Liver; Oleanolic Acid; Oxidative Phosphorylation; Rats; Triterpenes | 2020 |