bethanechol and pirenzepine

bethanechol has been researched along with pirenzepine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199019 (51.35)18.7374
1990's10 (27.03)18.2507
2000's7 (18.92)29.6817
2010's1 (2.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barocelli, E; Bertoni, S; Dallanoce, C; De Amici, M; De Micheli, C; Ernsberger, P; Roth, BL1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Fields, JZ; Gordon, JH; Keshavarzian, A; Urban, G; Willson, C1
Konopka, LM; Parsons, RL1
Dohi, T; Minami, N; Morita, K; Ohtsuki, H; Suemitsu, T; Tsujimoto, A1
Eltze, M; Kromer, W1
Bindslev, N; Winding, B1
Ballabeni, V; Barocelli, E; Impicciatore, M; Lavezzo, A; Morini, G1
Bernardini, MC; Blandizzi, C; Danesi, R; Del Tacca, M1
Gonzalez, FM; Jimenez-Heffernan, A; Latre, JM; Llamas-Elvira, JM; Martínez-Paredes, M; Mateo, A; Sopena, R; Torres, M1
Bartus, RT; Fisher, SK1
Rojas, E; Santos, RM1
Mihara, S; Nishi, S1
Rainsford, KD1
Cieszkowski, M; Konturek, SJ; Kromer, W; Szewczyk, K; Tasler, J1
Dodds, WJ; Gilbert, RJ1
Critchett, DJ; Joseph, JA; Lippa, AS1
Castell, DO; Castell, JA; Dalton, CB; Hassan, M1
Giachetti, A; Micheletti, R; Montagna, E1
Hsu, CT; Hyman, PE; Kao, HW; Ringer, MJ; Snape, WJ; Tomomasa, T1
Bellini, M; Bernardini, C; Costa, F; Del Tacca, M; Polloni, A; Soldani, G1
Allbee, WE; Gaginella, TS; Kachur, JF1
Kobayashi, H; Mochida, S1
Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H; Pruitt, RE; Uemura, N1
Blum, AL; Engler, H; Müller-Lissner, SA; Szelenyi, I1
Fong, J; Hirschowitz, BI; Molina, E1
Bertaccini, G; Comberlato, M; Coruzzi, G; Dobrilla, G; Lucchin, L1
Bernardini, C; Del Tacca, M; Martinotti, E; Soldani, G1
Gilbert, R; Goyal, RK; Rattan, S1
Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS1
Levin, RJ; Przyborski, SA1
Farnbauch, LJ; Robertson, KL; Rowland, NE1
Ouyang, A; Tandon, T; Wrzos, HF1
Althaus, H; Marti, M; Mevissen, M; Steiner, A1
Hirota, CL; McKay, DM1
Mevissen, M; Meylan, M; Pfeiffer, JB; Portier, CJ; Steiner, A1
Ahanya, SA; Lakshmanan, J; Liu, G; Mazdak, M; Oyachi, N; Ross, MG1

Reviews

1 review(s) available for bethanechol and pirenzepine

ArticleYear
Is field (vagal) stimulation of gastric acid secretion mediated by M1 or non-M1 muscarinic receptors? A methodical problem exemplified in the mouse stomach in vitro.
    Journal of autonomic pharmacology, 1991, Volume: 11, Issue:5

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Dicyclomine; Gastric Acid; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Mice; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Regression Analysis

1991

Other Studies

36 other study(ies) available for bethanechol and pirenzepine

ArticleYear
Novel oxotremorine-related heterocyclic derivatives: Synthesis and in vitro pharmacology at the muscarinic receptor subtypes.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Animals; Cells, Cultured; Drug Evaluation, Preclinical; Guinea Pigs; Heterocyclic Compounds; Humans; Ligands; Molecular Structure; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Rabbits; Receptors, Muscarinic; Recombinant Proteins

2007
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Chronic ethanol feeding produces a muscarinic receptor upregulation, but not a muscarinic supersensitivity in lower esophageal sphincter muscle.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Binding, Competitive; Cats; Esophagogastric Junction; Ethanol; Female; In Vitro Techniques; Male; Muscle, Smooth; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Cholinergic; Up-Regulation

1992
Bethanechol-induced responses in mudpuppy parasympathetic neurons.
    Neuropharmacology, 1992, Volume: 31, Issue:12

    Topics: Animals; Bethanechol; Bethanechol Compounds; Ganglia, Parasympathetic; Membrane Potentials; Necturus; Neurons; Parasympatholytics; Pirenzepine; Receptors, Nicotinic

1992
Involvement of Ca2+ entry and inositol trisphosphate-induced internal Ca2+ mobilization in muscarinic receptor-mediated catecholamine release in dog adrenal chromaffin cells.
    Neurochemistry international, 1992, Volume: 21, Issue:2

    Topics: Acetylcholine; Adrenal Medulla; Animals; Atropine; Bethanechol; Bethanechol Compounds; Biological Transport; Calcium; Calcium Channel Blockers; Catecholamines; Cells, Cultured; Dogs; Female; Gallic Acid; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Muscarine; Neomycin; Nicotine; Oxotremorine; Pirenzepine; Polymyxin B; Potassium Chloride; Receptors, Muscarinic; Retinaldehyde; Tetradecanoylphorbol Acetate

1992
Characterization of a muscarinic receptor controlling Cl- secretion in hen trachea.
    The American journal of physiology, 1990, Volume: 258, Issue:6 Pt 1

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Bumetanide; Calcium Channels; Chickens; Chlorides; Dicyclomine; Female; In Vitro Techniques; Ion Channels; Kinetics; Mucous Membrane; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea

1990
Effects of two new pirenzepine analogs on the contractile response of the guinea-pig oesophageal muscularis mucosae to acetylcholine, bethanechol, histamine and high potassium.
    European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2

    Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus; Guinea Pigs; Histamine; Histamine Antagonists; Male; Muscle Contraction; Piperidines; Pirenzepine; Potassium; Pyrilamine; Receptors, Muscarinic

1990
Differential affinities of AF-DX 116, atropine and pirenzepine for muscarinic receptors of guinea pig gastric fundus, atria and urinary bladder: might atropine distinguish among muscarinic receptor subtypes?
    Pharmacology, 1990, Volume: 40, Issue:5

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Dose-Response Relationship, Drug; Female; Gastric Fundus; Guinea Pigs; Heart Atria; Kinetics; Male; Muscarinic Antagonists; Myocardium; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Urinary Bladder

1990
Muscarinic control of gallbladder dynamics. A study using 99Tcm-HIDA and cholinergic agonists and antagonists.
    Nuclear medicine communications, 1990, Volume: 11, Issue:11

    Topics: Adult; Atropine; Bethanechol; Bethanechol Compounds; Female; Gallbladder; Humans; Imino Acids; Male; Organotechnetium Compounds; Parasympatholytics; Parasympathomimetics; Pirenzepine; Radionuclide Imaging; Technetium Tc 99m Lidofenin

1990
Regional differences in the coupling of muscarinic receptors to inositol phospholipid hydrolysis in guinea pig brain.
    Journal of neurochemistry, 1985, Volume: 45, Issue:4

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Brain; Carbachol; Corpus Striatum; Guinea Pigs; Hydrolysis; Oxotremorine; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Time Factors; Tissue Distribution

1985
Muscarinic receptor modulation of glucose-induced electrical activity in mouse pancreatic B-cells.
    FEBS letters, 1989, Jun-05, Volume: 249, Issue:2

    Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Cells, Cultured; Glucose; In Vitro Techniques; Membrane Potentials; Mice; Muscarine; Pancreas; Pirenzepine; Receptors, Muscarinic

1989
Muscarinic excitation and inhibition of neurons in the submucous plexus of the guinea-pig caecum.
    Neuroscience, 1989, Volume: 31, Issue:1

    Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscarine; Parasympathomimetics; Pirenzepine; Potassium; Receptors, Muscarinic; Submucous Plexus; Thionucleotides

1989
Quantitation by computerized visual image analysis of gastric mucosal lesions induced in mice and rats by non-steroidal anti-inflammatory drugs.
    Acta physiologica Hungarica, 1989, Volume: 73, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bethanechol; Bethanechol Compounds; Dinoprostone; Drug Synergism; Gastric Mucosa; Image Processing, Computer-Assisted; Mice; Peptic Ulcer Hemorrhage; Pirenzepine; Rats; Reserpine; Stomach Ulcer

1989
Comparison of telenzepine, pirenzepine and atropine on gastric acid and pepsin secretion in response to histamine, pentagastrin, bethanechol, sham-feeding and feeding.
    Digestion, 1989, Volume: 44, Issue:2

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Dogs; Food; Gastric Acid; Gastric Fistula; Histamine; Parasympatholytics; Pentagastrin; Pepsin A; Pirenzepine; Stomach

1989
Effect of selective muscarinic antagonists on peristaltic contractions in opossum smooth muscle.
    The American journal of physiology, 1986, Volume: 250, Issue:1 Pt 1

    Topics: Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Esophagus; Female; Male; Manometry; Muscle Contraction; Muscle, Smooth; Opossums; Peristalsis; Piperidines; Pirenzepine; Receptors, Muscarinic; Vagus Nerve

1986
Desensitization of muscarinic acetylcholine receptors: possible relation to receptor heterogeneity and phosphoinositides.
    Brain research, 1986, Feb-26, Volume: 366, Issue:1-2

    Topics: Acetylcholine; Animals; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Carbachol; Hippocampus; Male; Molecular Conformation; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic

1986
Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:5

    Topics: Adult; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus; Female; Gastrointestinal Agents; Humans; Male; Middle Aged; Muscle Contraction; Pirenzepine; Pressure; Propantheline; Random Allocation; Receptors, Muscarinic; Xerostomia

1986
AF-DX 116, a cardioselective muscarinic antagonist.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Cats; Dimethylphenylpiperazinium Iodide; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gastric Acid; Gastric Emptying; Guinea Pigs; Heart; Heart Rate; Male; Muscarine; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Pirenzepine; Rats; Receptors, Muscarinic

1987
[3H]QNB binding and contraction of rabbit colonic smooth muscle cells.
    The American journal of physiology, 1987, Volume: 253, Issue:5 Pt 1

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Binding, Competitive; Cell Count; Colon; Kinetics; Male; Microbial Collagenase; Muscle Contraction; Muscle, Smooth; Phenethylamines; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Rabbits; Receptors, Cholinergic

1987
The effects of the antimuscarinic drugs pirenzepine and atropine on plasma portal levels of somatostatin and gastrin in the dog.
    Journal of endocrinological investigation, 1987, Volume: 10, Issue:5

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Dogs; Gastrins; Parasympathomimetics; Pirenzepine; Somatostatin

1987
Antihistaminic and antimuscarinic effects of amitriptyline on guinea pig ileal electrolyte transport and muscle contractility in vitro.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2

    Topics: Amitriptyline; Animals; Bethanechol; Bethanechol Compounds; Electrolytes; Guinea Pigs; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Kinetics; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pirenzepine

1988
A novel muscarinic receptor antagonist AF-DX 116 differentially blocks slow inhibitory and slow excitatory postsynaptic potentials in the rabbit sympathetic ganglia.
    Life sciences, 1988, Volume: 42, Issue:22

    Topics: Action Potentials; Animals; Bethanechol; Bethanechol Compounds; Evoked Potentials; Ganglia, Sympathetic; Male; Methacholine Chloride; Methacholine Compounds; Pirenzepine; Rabbits; Receptors, Muscarinic; Synapses

1988
Muscarinic cholinergic receptor subtype on frog esophageal peptic cells: binding and secretion studies.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Esophagus; Imipramine; Kinetics; N-Methylscopolamine; Oxotremorine; Pepsinogens; Pirenzepine; Propranolol; Radioligand Assay; Rana catesbeiana; Receptors, Muscarinic; Scopolamine Derivatives

1988
Pirenzepine inhibits acid and pepsinogen secretion by the isolated perfused mouse stomach.
    Scandinavian journal of gastroenterology. Supplement, 1982, Volume: 72

    Topics: Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Drug Interactions; Gastric Acid; Gastric Mucosa; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Pepsinogens; Pirenzepine; Time Factors

1982
Effects of pirenzepine and atropine on vagal and cholinergic gastric secretion and gastrin release and on heart rate in the dog.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:2

    Topics: Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Cholinergic Fibers; Dogs; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Gastrins; Heart Rate; Pepsin A; Pirenzepine; Vagus Nerve

1983
Pirenzepine and exocrine secretions: a selective agent for gastric glands?
    Hepato-gastroenterology, 1983, Volume: 30, Issue:6

    Topics: Adult; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Exocrine Glands; Female; Gastric Juice; Humans; Lacrimal Apparatus; Male; Pirenzepine; Receptors, Muscarinic; Salivary Glands

1983
Comparative study of pA2 values of pirenzepine and atropine for guinea-pig gastric fundus and gastric smooth muscle.
    Pharmacology, 1984, Volume: 29, Issue:6

    Topics: Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Female; Gastric Fundus; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Pirenzepine; Receptors, Muscarinic; Stomach

1984
Pharmacologic identification, activation and antagonism of two muscarine receptor subtypes in the lower esophageal sphincter.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:2

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagogastric Junction; Hexamethonium Compounds; Opossums; Piperidines; Pirenzepine; Receptors, Muscarinic; Tetrodotoxin; Vagus Nerve

1984
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
    British journal of pharmacology, 1995, Volume: 114, Issue:4

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic

1995
Cholinergic modulation of electrogenic ion transport in different regions of the rat small intestine.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:7

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analysis of Variance; Animals; Atropine; Bethanechol; Carbachol; Chlorides; Diamines; Duodenum; Ileum; Intestinal Mucosa; Ion Transport; Jejunum; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Structure-Activity Relationship; Tetrodotoxin

1997
Brain muscarinic receptor subtypes mediating water intake and Fos following cerebroventricular administration of bethanecol in rats.
    Psychopharmacology, 2003, Volume: 167, Issue:2

    Topics: Animals; Atropine; Bethanechol; Dose-Response Relationship, Drug; Drinking Behavior; Injections, Intraventricular; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Water

2003
Mechanisms mediating cholinergic antral circular smooth muscle contraction in rats.
    World journal of gastroenterology, 2004, Nov-15, Volume: 10, Issue:22

    Topics: Anesthetics, Local; Animals; Benzofurans; Bethanechol; Calcium; Calcium Channel Blockers; Cholinergic Agonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Pertussis Toxin; Pirenzepine; Pyloric Antrum; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Signal Transduction; Tetrodotoxin

2004
In vitro effects of bethanechol on equine gastrointestinal contractility and functional characterization of involved muscarinic receptor subtypes.
    Journal of veterinary pharmacology and therapeutics, 2005, Volume: 28, Issue:6

    Topics: Animals; Area Under Curve; Bethanechol; Cecum; Dose-Response Relationship, Drug; Duodenum; Female; Gastrointestinal Motility; Horses; Jejunum; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pelvic Floor; Pirenzepine; Receptors, Muscarinic

2005
M3 muscarinic receptor-deficient mice retain bethanechol-mediated intestinal ion transport and are more sensitive to colitis.
    Canadian journal of physiology and pharmacology, 2006, Volume: 84, Issue:11

    Topics: Animals; Bethanechol; Cholinergic Fibers; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Ileum; Intestinal Mucosa; Ion Transport; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Agonists; Muscarinic Antagonists; Patch-Clamp Techniques; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; RNA, Messenger; Time Factors; Transcription, Genetic

2006
In vitro effects of bethanechol on specimens of intestinal smooth muscle obtained from the duodenum and jejunum of healthy dairy cows.
    American journal of veterinary research, 2007, Volume: 68, Issue:3

    Topics: Animals; Bethanechol; Cattle; Dairying; Dose-Response Relationship, Drug; Duodenum; Female; In Vitro Techniques; Jejunum; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Tropicamide

2007
Corticotropin-releasing factor inhibition of sheep fetal colonic contractility: mechanisms to prevent meconium passage in utero.
    American journal of obstetrics and gynecology, 2007, Volume: 196, Issue:4

    Topics: Animals; Bethanechol; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetus; Gastrointestinal Motility; Immunohistochemistry; Meconium; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pirenzepine; Pregnancy; Pregnancy, Animal; Probability; Receptors, Corticotropin-Releasing Hormone; Sensitivity and Specificity; Sheep, Domestic; Tissue Culture Techniques

2007