Compounds > betaine

betaine and vitamin b 12

betaine has been researched along with vitamin b 12 in 109 studies

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-199031 (28.44)18.7374
1990's7 (6.42)18.2507
2000's22 (20.18)29.6817
2010's38 (34.86)24.3611
2020's11 (10.09)2.80

Authors

AuthorsStudies
Poirier, LA1
Bogdanov, M; Filipova, R; Tsvetkov, S1
Baumgartner, R; Briones, P; Campistol, J; Lluch, M; Maya, A; Pascual, P; Ribes, A; Rodes, M; Suormala, T; Vilaseca, MA1
Allen, RH; Bartholomew, DW; Batshaw, ML; Francomano, CA; Roe, CR; Rosenblatt, D; Valle, DL1
Poirier, LA; Whitehead, VM1
Escala, C; Lentini, J; Taure, C1
Chavez, E; Kratzer, FH1
Birnbaum, J; Kaplan, L; White, RF1
Howell, JN; Jaenicke, L; Sauer, H1
Simon, A1
Cagen, LM; Friedmann, HC1
Fuller, HL; Keshavarz, K1
Demain, AL; White, RF2
Sharp, GS1
Piolanti, MP1
Allen, SH; Marston, HR1
Daniels, HJ1
Levy, H; Morrow, G; Mudd, SH1
Castellani, P; Montanari, MG; Montanari, P; Ruberti, A; Tobaldin, G1
Daniels, HJ; Demain, AL; Schnable, L; White, RF1
Agatov, PA; Galanina, LA1
Dudman, NP; Tyrrell, PA; Wilcken, B; Wilcken, DE1
Allen, RH; Lindenbaum, J; Stabler, SP1
Allen, RH; Lindenbaum, J; Savage, DG; Stabler, SP1
Kang, SS1
Albright, CD; Citarella, MT; da Costa, KA; Mar, MH; Shin, OH; Zeisel, SH1
Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J1
Cooney, CA; Kodell, RL; Moore, SR; Wolff, GL1
Berrettini, M; Burlina, A; Cella, G; Girolami, A; Motta, G; Sbarai, A; Strauss, W1
Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Robson, RA1
Hochstein, LI; Tomlinson, GA1
Jirtle, RL; Waterland, RA1
KRATZER, FH1
MORRISON, LM1
HEUSER, GF; NORRIS, LC; YOUNG, RJ1
ERICSON, LE; HARPER, AE1
ELVEHJEM, CA; ERICSON, LE; HARPER, AE; WILLIAMS, JN1
BEST, CH; LUCAS, CC; PATTERSON, JM; YOUNG, RJ1
ANDERSON, EI; HSU, PT; STEKOL, JA; WATJEN, A; WEISS, S1
Bleie, Ø; Holm, PI; Lien, EA; Nordrehaug, JE; Nygård, O; Refsum, H; Ueland, PM1
GILLIS, MB; NORRIS, LC1
Blom, HJ; den Heijer, M; Holm, PI; Keijzer, MB; Midttun, Ø; Ueland, PM; Vollset, SE1
Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA1
Borderie, D; Deschênes, G; Favier, R; Frémeaux-Bacchi, V; Giraudier, S; Guigonis, V; Massy, Z; Mougenot, B; Rosenblatt, DS1
Boxer, AL; Finley, R; Goldman, J; Johnston, K; Kramer, JH; Miller, BL1
Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM1
Alscher, DM; Benzinger, P1
Heyrovský, M; Kohlíková, E; Navrátil, T; Pelclová, D; Petr, M; Pristoupil, TI; Pristoupilová, K; Senholdová, Z1
Gulevich, RG; Latypov, IF; Os'kina, IN; Pliusnina, IZ; Prasolova, LA; Trut, LN; Vsevolodov, EB1
Dolinoy, DC; Lin, JR; Shi, X; Smith, CA; Tahiliani, KG; Waterland, RA1
Grotmol, T; Holm, PI; Hustad, S; Schneede, J; Ueland, PM; Vollset, SE1
Blom, HJ; Clarke, R; de Groot, LC; Eussen, SJ; Hoefnagels, WH; Ueland, PM; van Staveren, WA1
Greenberg, CR; Prasad, AN; Prasad, C; Sharma, AP1
Cho, E; Hankinson, SE; Holmes, M; Willett, WC1
Bonham, MP; Clarkson, TW; Davidson, PW; Duffy, EM; McNulty, H; Molloy, AM; Myers, GJ; Robson, PJ; Scott, JM; Shamlaye, CF; Strain, J; Ueland, PM; Wallace, JM; Ward, M1
Chu, J; Li, KT; Liu, DH; Wang, YH; Zhang, SL; Zhuang, YP1
Chu, J; Li, KT; Li, YL; Liu, DH; Wang, YH; Zhang, SL; Zhuang, YP1
Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M; Slow, S1
Os'kina, IN; Pliusnina, IZ; Prasolova, LA; Trut, LN1
Cho, E; Dougherty, L; Giovannucci, E; Jacques, PF; Lee, JE; Selhub, J; Zeisel, SH1
Cooney, CA; Downing, C; Johnson, TE; Larson, C; Leakey, TI; Rafferty, TM; Siegfried, RN1
Deth, RC; Kharbanda, KK; Waly, MI1
Dowd, SE; Harris, RA; Kellermayer, R; Schaible, TD; Smith, CW1
Campion, J; Cordero, P; Martínez, JA; Milagro, FI2
Baccarelli, A; Boeke, CE; Burris, HH; Gillman, M; Kleinman, KP; Litonjua, AA; Rifas-Shiman, SL; Tarantini, L1
Gillman, MW; Oken, E; Rifas-Shiman, SL; Villamor, E1
Bjelland, I; Drevon, CA; Engedal, K; Nurk, E; Nygaard, HA; Refsum, H; Smith, DA; Tell, GS; Ueland, PM; Vollset, SE1
Billington, CJ; Georgieff, MK; Gopalakrishnan, R; Hodges, JS; Petryk, A; Schmidt, B; Schotta, G; Zhang, L1
Boeke, CE; Gillman, MW; Hughes, MD; Oken, E; Rifas-Shiman, SL; Villamor, E1
Delaney, C; Hewagama, A; Hoeltzel, MF; Johnson, K; Mickelson, B; Richardson, BC; Sawalha, AH; Strickland, FM; Wu, A; Yung, R1
Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH1
Ballesteros, M; Berrocal-Zaragoza, MI; Cavallé-Busquets, P; Fernandez-Ballart, JD; Fernàndez-Roig, S; Murphy, MM; Salat-Batlle, J; Ueland, PM1
Collin, SM1
Gao, XL; Gu, XF; Han, LS; Huang, Z; Ji, WJ; Li, XY; Qiu, WJ; Wang, Y; Ye, J; Zhang, HW1
Liu, YP; Yang, YL1
Dyer, RA; Innis, SM; King, DJ; Mulder, KA; Wu, BT1
Ashapkin, VV; Fedotova, IB; Merzalov, IB; Pavlova, GV; Perepelkina, OV; Poletaeva, II; Surina, NM1
Chen, W; Li, KT; Peng, WF; Xia, W1
Baumgartner, MR; Burda, P; Chinnery, PF; Demirkol, M; Dionisi-Vici, C; Dobbelaere, D; Fowler, B; Froese, DS; Gökcay, G; Häberle, J; Huemer, M; Lossos, A; Mengel, E; Morris, AA; Mulder-Bleile, R; Niezen-Koning, KE; Parini, R; Plecko, B; Rokicki, D; Schiff, M; Schimmel, M; Sewell, AC; Sperl, W; Spiekerkoetter, U; Steinmann, B; Suormala, T; Taddeucci, G; Trefz, F; Trejo-Gabriel-Galán, JM; Tsuji, M; Vilaseca, MA; von Kleist-Retzow, JC; Walker, V; Zeev, BB; Zeman, J1
Berge, RK; Bjørndal, B; Lysne, V; Nordrehaug, JE; Nygård, O; Skorve, J; Vik, R1
Cavallé-Busquets, P; Fernandez-Ballart, JD; Murphy, MM; Solé-Navais, P1
Kumar, T; Sharma, GS; Singh, LR1
Awwad, HM; Geisel, J; Keller, M; Obeid, R1
Aris, IM; Chong, MF; Chong, YS; Fortier, MV; Gluckman, PD; Godfrey, KM; Kramer, MS; Lee, YS; Quah, PL; Saw, SM; Tint, MT; van Lee, L; Yap, FK1
Bell, E; Francq, BG; Mactier, R; McConnachie, A; Smith, JR; Zimmer, N1
Liu, J; Liu, X; Meng, Q; Peng, Y; Xu, H; Zhao, S; Zhou, N1
Wu, MM; Yang, F1
Chapel-Crespo, C; Chu, P; Diaz, G; Oishi, K; Prasun, P; Williamson, A1
Che, L; Chen, Y; Fang, Z; Feng, B; Li, J; Lin, Y; Liu, H; Mou, D; Wang, J; Xu, S1
Gylling, B; Häggström, J; Hallmans, G; Johansson, I; Midttun, Ø; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Ulvik, A; Van Guelpen, B1
Barzilay, E; Berger, H; Caudill, MA; Croxford, R; Kim, YI; Ly, A; Malysheva, O; Masih, SP; Moon, A; O'Connor, DL; Plumptre, L; Sohn, KJ; Visentin, CE1
Bassett, JK; Brinkman, MT; Buchanan, DD; Chamberlain, JA; Dugué, PA; English, DR; Giles, GG; Hodge, AM; Hopper, JL; Joo, JE; Jung, CH; Makalic, E; Milne, RL; Schmidt, DF; Southey, MC1
Crider, KS; Mitchell, AA; Parker, SE; Petersen, JM; Tinker, SC; Werler, MM1
Bustamante, A; Cakora, P; Felder, MR; Hall-South, A; Owen, A; Shorter, KR; Smith, N; Vrana, PB; Yadon, N1
Akemokwe, FM; Ceesay, K; James, PT; Jawla, O; Mohammed, NI; Prentice, AM; Silver, MJ; Sise, EA; Sonko, B1
DiNicolantonio, JJ; McCarty, MF; O'Keefe, JH1
Florindo, C; Macário, MC; Tavares de Almeida, I; Vieira, D1
Ampong, I; Eid, N; Griffiths, HR; Morgan, HL; Rouillon, C; Watkins, AJ1
Braconnier, A; Desmons, A; Garnotel, R; Gillery, P; Jaisson, S; Rieu, P; Wynckel, A1
Bergamini, C; Capelli, I; Cappuccilli, M; Cianciolo, G; Conte, D; Donati, G; Giacomelli, FA; La Manna, G; Natali, T1
Fishchuk, L; Gorovenko, N; Medvedieva, N; Rossokha, Z; Sheyko, L1
Cheng, X; Li, KT; Yang, Y1
Ragsdale, SW1
Cruz, M; Diaz-Flores, M; Fernandez-Osornio, LF; Gomez-Diaz, RA; Gonzalez-Carranza, E; Hernández-Pineda, J; Maldonado-Rodriguez, R; Mondragon-Gonzalez, R; Sharma, T; Valladares-Salgado, A; Wacher, NH1
Chen, Z; Dong, H; He, R; Jin, Y; Kang, L; Li, D; Li, M; Liu, X; Liu, Y; Qi, J; Song, J; Wang, F; Xiao, H; Yan, H; Yang, Y; Zhang, Y; Zheng, H1
Arthurs, AL; Jankovic-Karasoulos, T; Roberts, CT; Smith, MD; Williamson, JM1
Chen, S; Fang, AP; He, TT; Huang, BX; Huang, RZ; Huang, ZH; Li, SY; Liu, XZ; Liu, ZY; Lu, XT; Luo, Y; Maierhaba, W; Mo, QW; Wang, YF; Wang, YN; Yang, MT; Zhang, XG; Zhu, HL1

Reviews

10 review(s) available for betaine and vitamin b 12

ArticleYear
Microbial biosynthesis of B12-like compounds.
    Annual review of microbiology, 1970, Volume: 24

    Topics: Amino Acids; Bacteria; Betaine; Chemical Phenomena; Chemistry; Culture Media; Genetics, Microbial; Hydro-Lyases; Levulinic Acids; Nucleotidyltransferases; Oxygen; Porphyrins; Vitamin B 12

1970
Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1993, Volume: 7, Issue:14

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Aged; Animals; Betaine; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Methylmalonyl-CoA Mutase; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency

1993
Remethylation defects: guidelines for clinical diagnosis and treatment.
    European journal of pediatrics, 1998, Volume: 157 Suppl 2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12

1998
Folate and B12 in prostate cancer.
    Advances in clinical chemistry, 2013, Volume: 60

    Topics: Betaine; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Male; Meta-Analysis as Topic; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Vitamin B 12

2013
[Advances in the clinical and laboratory studies on methylmalonic aciduria combined with homocysteinemia type cblC].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2013, Volume: 51, Issue:4

    Topics: Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Betaine; Carrier Proteins; Child; China; DNA Mutational Analysis; Gas Chromatography-Mass Spectrometry; Genotype; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Infant; Methylmalonic Acid; Mutation; Oxidoreductases; Vitamin B 12

2013
Early pregnancy B vitamin status, one carbon metabolism, pregnancy outcome and child development.
    Biochimie, 2016, Volume: 126

    Topics: Betaine; Carbon; Child; Child Development; Child, Preschool; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Trimester, Third; Sarcosine; Vitamin B 12

2016
Homocystinuria: Therapeutic approach.
    Clinica chimica acta; international journal of clinical chemistry, 2016, Jul-01, Volume: 458

    Topics: Betaine; Cystathionine beta-Synthase; Homocystinuria; Humans; Hydrogen-Ion Concentration; Oxidative Stress; Small Molecule Libraries; Vitamin B 12; Vitamin B 6

2016
[Research advances in the association between maternal intake of methyl donor nutrients during pregnancy and DNA methylation in offspring].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2017, Volume: 19, Issue:5

    Topics: Betaine; Choline; DNA Methylation; Female; Folic Acid; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Vitamin B 12

2017
Vitamin B Supplementation and Nutritional Intake of Methyl Donors in Patients with Chronic Kidney Disease: A Critical Review of the Impact on Epigenetic Machinery.
    Nutrients, 2020, Apr-27, Volume: 12, Issue:5

    Topics: Betaine; Cardiovascular Diseases; Choline; Dietary Supplements; DNA Methylation; Eating; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methionine; Nutritional Physiological Phenomena; Renal Insufficiency, Chronic; Uremia; Vitamin B 12; Vitamin B 6

2020
High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus.
    Nutrients, 2022, Sep-22, Volume: 14, Issue:19

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Neural Tube Defects; Pregnancy; Thymidylate Synthase; Vitamin B 12

2022

Trials

8 trial(s) available for betaine and vitamin b 12

ArticleYear
Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:2

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Betaine; Choline; Coronary Angiography; Dietary Supplements; Drug Administration Schedule; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Methyltransferases; Middle Aged; Sarcosine; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2004
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.
    The British journal of nutrition, 2007, Volume: 98, Issue:5

    Topics: Aged; Attention; Betaine; Choline; Cognition; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Neuropsychological Tests; Psychomotor Performance; Sarcosine; Vitamin B 12; Vitamin B Complex

2007
Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2009, Volume: 19, Issue:11

    Topics: Adult; Betaine; Biomarkers; Choline; Creatinine; Cross-Over Studies; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Lipids; Male; Sarcosine; Time Factors; Vitamin B 12; Young Adult

2009
Trimethylamine-N-oxide and its biological variations in vegetarians.
    European journal of nutrition, 2017, Volume: 56, Issue:8

    Topics: Adult; Aged; Betaine; Biomarkers; Diet, Vegetarian; Female; Humans; Male; Methylamines; Middle Aged; Sarcosine; Single-Blind Method; Vegetarians; Vitamin B 12

2017
A Randomized, Single-Blind, Crossover Trial of Recovery Time in High-Flux Hemodialysis and Hemodiafiltration.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 69, Issue:6

    Topics: Aged; Aged, 80 and over; beta 2-Microglobulin; Betaine; Cross-Over Studies; Female; Health Status; Hemodiafiltration; Humans; Hypotension; Interleukin-6; Kidney Failure, Chronic; Male; Middle Aged; Parathyroid Hormone; Phosphates; Potassium; Quality of Life; Recovery of Function; Renal Dialysis; Single-Blind Method; Time Factors; United Kingdom; Urea; Vitamin B 12

2017
Maternal methyl donor supplementation during gestation counteracts bisphenol A-induced oxidative stress in sows and offspring.
    Nutrition (Burbank, Los Angeles County, Calif.), 2018, Volume: 45

    Topics: Actins; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Benzhydryl Compounds; Betaine; Catalase; Choline; Diet; Dietary Supplements; Female; Folic Acid; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Malondialdehyde; Maternal Nutritional Physiological Phenomena; Oxidative Stress; Phenols; Placenta; Pregnancy; Superoxide Dismutase; Swine; Vitamin B 12

2018
A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia.
    PLoS medicine, 2019, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Betaine; Dietary Supplements; Female; Folic Acid; Gambia; Homocysteine; Humans; Middle Aged; Nutritional Status; Riboflavin; Vitamin B 12; Young Adult

2019
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial.
    European journal of nutrition, 2023, Volume: 62, Issue:4

    Topics: Adolescent; Adult; Aged; Betaine; Dietary Supplements; Double-Blind Method; East Asian People; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 12; Vitamin B Complex; Young Adult

2023

Other Studies

91 other study(ies) available for betaine and vitamin b 12

ArticleYear
Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes.
    Journal of the National Cancer Institute, 1975, Volume: 54, Issue:1

    Topics: Animals; Betaine; Carcinogens; Carcinoma, Hepatocellular; Choline; Diet; Ethanolamines; Folic Acid; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methotrexate; Neoplasms, Experimental; Nitrosamines; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Vitamin B 12

1975
[Effect of betaine hydrochloride on broiler chickens when used alone or in combination with vitamin B12].
    Veterinarno-meditsinski nauki, 1976, Volume: 13, Issue:6

    Topics: Animal Nutritional Physiological Phenomena; Animals; Betaine; Body Weight; Chickens; Drug Interactions; Vitamin B 12

1976
Methylmalonic aciduria with homocystinuria: biochemical studies, treatment, and clinical course of a Cbl-C patient.
    European journal of pediatrics, 1990, Volume: 149, Issue:6

    Topics: Betaine; Child, Preschool; Female; Homocystinuria; Humans; Infant; Male; Malonates; Metabolism, Inborn Errors; Methylmalonic Acid; Mutation; Vitamin B 12

1990
Therapeutic approaches to cobalamin-C methylmalonic acidemia and homocystinuria.
    The Journal of pediatrics, 1988, Volume: 112, Issue:1

    Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Betaine; Carnitine; Child, Preschool; Female; Fibroblasts; Homocystinuria; Humans; Hydroxocobalamin; Infant; Injections, Intramuscular; Leucovorin; Male; Malonates; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency

1988
Folate deficiency and formiminoglutamic acid excretion during chronic diethylnitrosamine administration to rats.
    Cancer research, 1973, Volume: 33, Issue:2

    Topics: Animals; Betaine; Carcinogens; Choline; Diet; Drinking; FIGLU Test; Folic Acid; Folic Acid Deficiency; Glutamates; Histidine; Liver; Male; Methionine; Nitrosamines; Rats; Stimulation, Chemical; Transferases; Urocanate Hydratase; Vitamin B 12

1973
[Hypochylia in the aged. Its treatment with an acid combination of pepsin and vitamins].
    Revista espanola de las enfermedades del aparato digestivo, 1970, Jun-01, Volume: 31, Issue:5

    Topics: Achlorhydria; Aged; Betaine; Citrates; Female; Humans; Hydrochloric Acid; Lactates; Male; Niacinamide; Pepsin A; Vitamin B 12; Vitamins

1970
Effect of diet on foot pad dermatitis in poults.
    Poultry science, 1974, Volume: 53, Issue:2

    Topics: Aminobutyrates; Animal Feed; Animals; Betaine; Biotin; Body Weight; Chickens; Cystine; Diet; Ethers; Female; Foot Dermatoses; Glycine max; Homocystine; Male; Methionine; Niacinamide; Poultry Diseases; Sulfates; Vitamin B 12; Vitamin E

1974
Betaine-homocysteine transmethylase in Pseudomonas denitrificans, a vitamin B 12 overproducer.
    Journal of bacteriology, 1973, Volume: 113, Issue:1

    Topics: Betaine; Biological Assay; Cell-Free System; Chromatography, Paper; Culture Media; Enzyme Repression; Homocysteine; Hydrogen-Ion Concentration; Lactobacillus; Methionine; Methyltransferases; Mutation; Pantothenic Acid; Pseudomonas; Temperature; Vitamin B 12

1973
[Importance and regulation of the cobalamin-dependent methionine synthetase and the betaine: homocystein methyltransferase in methionine and tetrahydrofolic acid metabolism of the rat].
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1973, May-21, Volume: 160, Issue:3

    Topics: Animals; Betaine; Coenzyme A; Diet; Female; Folic Acid; Homocysteine; Kidney; Liver; Methionine; Methylation; Methyltransferases; Rats; Tetrahydrofolates; Vitamin B 12

1973
[The role of methionine in the metabolism of vitamin B 12- and methionine-dependent Escherichia coli strains].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite naturwissenschaftliche Abt.: Allgemeine, landwirtschaftliche und technische Mikrobiologie, 1970, Volume: 124, Issue:6

    Topics: Bacteriological Techniques; Betaine; Choline; Escherichia coli; Methionine; Vitamin B 12

1970
Relationship of arginine and methionine to creatine formation in chicks.
    The Journal of nutrition, 1971, Volume: 101, Issue:7

    Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Body Weight; Chickens; Choline; Choline Deficiency; Creatine; Cystine; Deficiency Diseases; Depression, Chemical; Folic Acid; Folic Acid Deficiency; Glycine; Glycine max; Guanidines; Lipid Metabolism; Liver; Male; Methionine; Muscles; Ornithine; Stimulation, Chemical; Urea; Vitamin B 12; Vitamin B 12 Deficiency; Zea mays

1971
Porphyrin overproduction by Pseudomonas denitrificans: essentiality of betaine and stimulation by ethionine.
    Journal of bacteriology, 1971, Volume: 107, Issue:2

    Topics: Absorption; Acetates; Betaine; Chromatography, Thin Layer; Culture Media; Ethionine; Fermentation; Heme; Models, Theoretical; Pigments, Biological; Porphyrins; Pseudomonas; Spectrophotometry; Time Factors; Vitamin B 12

1971
Treatment for low tolerance to dentures: supplemental report.
    The Journal of prosthetic dentistry, 1967, Volume: 17, Issue:3

    Topics: Achlorhydria; Betaine; Cellulose; Dentures; Humans; Liver Extracts; Mouth, Edentulous; Pepsin A; Quaternary Ammonium Compounds; Riboflavin; Stomatitis; Vitamin B 12

1967
[Clinical experiences with high doses of natural cortical extract].
    La Clinica terapeutica, 1969, Mar-15, Volume: 48, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adult; Betaine; Female; Humans; Injections, Intravenous; Male; Middle Aged; Vitamin B 12

1969
Factors affecting formiminoglutamic acid excretion in vitamin B 12 deficiency.
    The Biochemical journal, 1970, Volume: 116, Issue:4

    Topics: Aminopterin; Animals; Betaine; Female; Folic Acid; Folic Acid Deficiency; Glutarates; Histidine; Male; Methionine; Rats; Sheep; Vitamin B 12; Vitamin B 12 Deficiency

1970
Some factors influencing vitamin B 12 production by Pseudomonas denitrificans.
    Canadian journal of microbiology, 1970, Volume: 16, Issue:9

    Topics: Acids; Amino Acids; Betaine; Carbohydrates; Cobalt; Culture Media; Glutamates; Glycine; Hydrogen-Ion Concentration; Minerals; Oxalates; Phosphates; Pseudomonas; Vitamin B 12

1970
Deranged B 12 metabolism: effects on sulfur amino acid metabolism.
    Biochemical medicine, 1970, Volume: 4, Issue:3

    Topics: Adenosine Triphosphate; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Betaine; Brain Chemistry; Carbon Isotopes; Child, Preschool; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Isomerases; Kidney; Liver; Male; Malonates; Methionine; Methyltransferases; Transferases; Vitamin B 12

1970
[High doses of natural adrenal-cortex extract in infectious and general pathology. (Clinico-statistical study)].
    Il Policlinico. Sezione medica, 1971, Volume: 78, Issue:3

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Betaine; Cholangitis; Enterocolitis, Pseudomembranous; Female; Hepatitis A; Humans; Infections; Male; Middle Aged; Respiratory Tract Infections; Tissue Extracts; Urinary Tract Infections; Vitamin B 12

1971
Catabolism of betaine and its relationship to cobalamin overproduction.
    Biochimica et biophysica acta, 1971, Apr-20, Volume: 237, Issue:1

    Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12

1971
Specificity of the stimulatory effect of betaine on the vitamin B12 fermentation.
    Nature, 1968, Dec-28, Volume: 220, Issue:5174

    Topics: Betaine; Choline; Fermentation; Methionine; Pseudomonas; Stimulation, Chemical; Vitamin B 12

1968
[The effect of conditions instrumental in the process of methylation on the biosynthesis of streptomycin by the Act. streptomycini LS-1 strain].
    Doklady Akademii nauk SSSR, 1966, Jan-01, Volume: 166, Issue:1

    Topics: Betaine; Creatinine; Methionine; Methylation; Streptomyces; Streptomycin; Vitamin B 12; Vitamin B Complex

1966
Homocystinuria--the effects of betaine in the treatment of patients not responsive to pyridoxine.
    The New England journal of medicine, 1983, Aug-25, Volume: 309, Issue:8

    Topics: Amino Acids; Amino Acids, Sulfur; Betaine; Cystathionine beta-Synthase; Cysteine; Female; Homocysteine; Homocystinuria; Humans; Male; Pyridoxine; Vitamin B 12

1983
Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:11

    Topics: Adolescent; Adult; Aged; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chromatography; Creatinine; Cystathionine beta-Synthase; Female; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methionine; Methyltransferases; Middle Aged; Rats; Rats, Sprague-Dawley; Reference Values; Renal Insufficiency; Sarcosine; Vitamin B 12; Vitamin B 12 Deficiency

1993
Treatment of hyperhomocyst(e)inemia: physiological basis.
    The Journal of nutrition, 1996, Volume: 126, Issue:4 Suppl

    Topics: Betaine; Folic Acid; Homocysteine; Humans; Vitamin B 12

1996
Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency.
    Journal of cellular biochemistry, 1997, Volume: 64, Issue:2

    Topics: Animals; Apoptosis; Betaine; Cell Line; Choline Deficiency; Culture Media; Folic Acid; Liver; Male; Methylation; Rats; Rats, Inbred F344; Vitamin B 12

1997
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:11

    Topics: 5-Methylcytosine; Agouti Signaling Protein; Animals; Betaine; Choline; Cytosine; Dietary Supplements; Female; Folic Acid; Gene Expression Regulation; Genomic Imprinting; Hair Color; Intercellular Signaling Peptides and Proteins; Male; Methionine; Mice; Mice, Inbred Strains; Pregnancy; Proteins; S-Adenosylmethionine; Vitamin B 12; Zinc

1998
Tissue factor pathway inhibitor levels in patients with homocystinuria.
    Thrombosis research, 2000, Jun-01, Volume: 98, Issue:5

    Topics: Adult; Betaine; Biomarkers; Cystathionine beta-Synthase; Endothelium; Factor VII; Female; Fibrinolytic Agents; Heparin; Homocysteine; Homocystinuria; Homozygote; Humans; Lipoproteins; Male; Protein C; Pyridoxine; Serine Proteinase Inhibitors; Thrombomodulin; Thromboplastin; Vascular Diseases; Vitamin B 12

2000
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.
    Kidney international, 2001, Volume: 59, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Betaine; Betaine-Homocysteine S-Methyltransferase; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methyltransferases; Middle Aged; Peritoneal Dialysis; Predictive Value of Tests; Pyridoxine; Renal Dialysis; Sarcosine; Uremia; Vitamin B 12; Zinc

2001
The growth of Paracoccus halodenitrificans in a defined medium.
    Canadian journal of microbiology, 1984, Volume: 30, Issue:6

    Topics: Ammonium Sulfate; Betaine; Carbohydrate Metabolism; Carbohydrates; Culture Media; Ferrous Compounds; Magnesium Sulfate; Methionine; Nitrates; Paracoccus; Phosphates; Potassium Compounds; Sodium Chloride; Sodium Lactate; Thiamine; Vitamin B 12

1984
Transposable elements: targets for early nutritional effects on epigenetic gene regulation.
    Molecular and cellular biology, 2003, Volume: 23, Issue:15

    Topics: Alleles; Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA Methylation; DNA Transposable Elements; Exons; Folic Acid; Gene Expression Regulation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Models, Genetic; Molecular Sequence Data; Nutritional Physiological Phenomena; Phenotype; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Vitamin B 12

2003
The effect of vitamin B12 upon the utilization of choline and betaine by the young poult.
    The Journal of nutrition, 1952, Volume: 48, Issue:2

    Topics: Alkaloids; Animals; Betaine; Choline; Humans; Turkeys; Vitamin B 12; Vitamin B Complex

1952
Use of betaine-lipotropic combinations in clinical practice.
    Geriatrics, 1953, Volume: 8, Issue:12

    Topics: Arteriosclerosis; Betaine; Choline; Corrinoids; Glycine; Humans; Lipotropic Agents; Liver Extracts; Vitamin B 12; Vitamin B Complex

1953
The utilization by vitamin B12-deficient chicks of monomethylaminoethanol, homocystine and betaine as precursors of choline and methionine.
    The Journal of nutrition, 1954, Jun-10, Volume: 53, Issue:2

    Topics: Amino Acids; Amino Alcohols; Animals; Betaine; Chickens; Choline; Homocystine; Methionine; Vitamin B 12; Vitamin B 12 Deficiency

1954
Effect of diet on betaine-homocysteine transmethylase of rat liver. III. B-vitamins other than vitamin B12.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1955, Volume: 90, Issue:1

    Topics: Animals; Betaine; Diet; Enzymes; Folic Acid; Homocysteine S-Methyltransferase; Liver; Rats; Vitamin B 12; Vitamin B Complex; Vitamins

1955
Effect of diet on the betaine-homocysteine transmethylase activity of rat liver. II. Vitamin B12.
    The Journal of biological chemistry, 1956, Volume: 219, Issue:1

    Topics: Animals; Betaine; Diet; Enzymes; Homocysteine S-Methyltransferase; Liver; Rats; Vitamin B 12; Vitamin B Complex

1956
The role of dietary betaine and vitamin B12 in choline formation by the rat.
    The Journal of biological chemistry, 1957, Volume: 224, Issue:1

    Topics: Alkaloids; Animals; Betaine; Choline; Corrinoids; Diet; Rats; Vitamin B 12

1957
Vitamin B12 and folic acid in relation to methionine synthesis from betaine in vivo and invitro.
    The Journal of biological chemistry, 1957, Volume: 226, Issue:1

    Topics: Betaine; Choline; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

1957
The effect of vitamin B12 on the response of chicks to betaine and choline.
    The Journal of nutrition, 1951, Volume: 43, Issue:2

    Topics: Animals; Betaine; Chickens; Choline; Vitamin B 12

1951
Betaine and folate status as cooperative determinants of plasma homocysteine in humans.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:2

    Topics: Adult; Aged; Betaine; Choline; Creatinine; Dose-Response Relationship, Drug; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6

2005
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:6

    Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12

2004
Late-onset thrombocytic microangiopathy caused by cblC disease: association with a factor H mutation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:3

    Topics: Anemia; Betaine; Child; Combined Modality Therapy; Complement Factor H; Drug Therapy, Combination; Endothelium, Vascular; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Haptoglobins; Hemolytic-Uremic Syndrome; Humans; Hydroxocobalamin; Hypertension; Kidney; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Nephrotic Syndrome; Plasma Exchange; Point Mutation; Proteinuria; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Renal Dialysis; Vitamin B 12

2005
Executive dysfunction in hyperhomocystinemia responds to homocysteine-lowering treatment.
    Neurology, 2005, Apr-26, Volume: 64, Issue:8

    Topics: Adult; Anticoagulants; Betaine; Cognition Disorders; Confusion; Disease Progression; Drug Therapy, Combination; Folic Acid; Frontal Lobe; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Remission Induction; Seizures; Treatment Outcome; Vitamin B 12; Vitamin B 6

2005
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:4

    Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12

2005
[Untreated homocystinuria in adulthood].
    Deutsche medizinische Wochenschrift (1946), 2005, Oct-28, Volume: 130, Issue:43

    Topics: Adult; Age Factors; Angina Pectoris; Betaine; Diagnosis, Differential; Drug Therapy, Combination; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Intervertebral Disc Displacement; Lens Subluxation; Male; Marfan Syndrome; Myopia; Osteoporosis; Retinal Detachment; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2005
Diagnostic significance of urinary thiodiglycolic acid as a possible tool for studying the role of vitamins B12 and folates in the metabolism of thiolic substances.
    Physiological research, 2007, Volume: 56, Issue:1

    Topics: Adult; Betaine; Biomarkers; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Leucovorin; Male; Sulfhydryl Compounds; Thioglycolates; Vitamin B 12; Vitamin B 12 Deficiency

2007
[The effect of methyl-containing supplements during pregnancy on the phenotypic modification of offspring hair color in rats].
    Genetika, 2006, Volume: 42, Issue:1

    Topics: Agouti Signaling Protein; Animals; Betaine; Choline; Color; Dietary Supplements; Electron Spin Resonance Spectroscopy; Female; Folic Acid; Hair Color; Heterozygote; Homozygote; Intercellular Signaling Peptides and Proteins; Male; Methionine; Phenotype; Pigments, Biological; Pregnancy; Rats; Vitamin B 12; Zinc

2006
Maternal methyl supplements increase offspring DNA methylation at Axin Fused.
    Genesis (New York, N.Y. : 2000), 2006, Volume: 44, Issue:9

    Topics: Alleles; Animals; Axin Protein; Betaine; Body Weight; Choline; CpG Islands; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Gene Expression Regulation; Heterozygote; Introns; Mice; Mice, Inbred C57BL; Models, Genetic; Polymerase Chain Reaction; Pregnancy; Random Allocation; Repressor Proteins; Sulfites; Vitamin B 12

2006
Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->t genotypes and B-vitamin status in a large-scale epidemiological study.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:4

    Topics: Betaine; Choline; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins

2007
Hemolytic uremic syndrome (HUS) secondary to cobalamin C (cblC) disorder.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:12

    Topics: Acute Kidney Injury; Betaine; Brain Diseases, Metabolic, Inborn; Carnitine; Carrier Proteins; Combined Modality Therapy; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Hemolytic-Uremic Syndrome; Homocystinuria; Homozygote; Humans; Hydroxocobalamin; Infant, Newborn; Longitudinal Studies; Methylmalonic Acid; Mutation; Oxidoreductases; Proto-Oncogene Proteins c-cbl; Treatment Outcome; Vitamin B 12

2007
Nutrients involved in one-carbon metabolism and risk of breast cancer among premenopausal women.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:12

    Topics: Adult; Betaine; Breast Neoplasms; Choline; Diet; Female; Food; Humans; Metabolic Networks and Pathways; Methionine; Middle Aged; Premenopause; Pteroylpolyglutamic Acids; Risk Factors; Vitamin B 12; Vitamin B 6

2007
Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study.
    The American journal of clinical nutrition, 2008, Volume: 87, Issue:2

    Topics: Adult; Betaine; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methionine; Parturition; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Third; Seychelles; Vitamin B 12; Vitamin B Complex

2008
An effective and simplified pH-stat control strategy for the industrial fermentation of vitamin B(12) by Pseudomonas denitrificans.
    Bioprocess and biosystems engineering, 2008, Volume: 31, Issue:6

    Topics: Betaine; Chemistry Techniques, Analytical; Choline; Culture Media; Fermentation; Glucose; Hydrogen-Ion Concentration; Industrial Microbiology; Microbiological Techniques; Molasses; Oxygen; Pseudomonas; Time Factors; Vitamin B 12

2008
Improved large-scale production of vitamin B12 by Pseudomonas denitrificans with betaine feeding.
    Bioresource technology, 2008, Volume: 99, Issue:17

    Topics: Aminolevulinic Acid; Analysis of Variance; Betaine; Cell Proliferation; Fermentation; Hydrogen-Ion Concentration; Pseudomonas; Vitamin B 12

2008
[Methyl-containing diet of mothers affects the AGOUTI gene expression in the offspring of rats with various behavioral types].
    Genetika, 2009, Volume: 45, Issue:5

    Topics: Aggression; Agouti Signaling Protein; Animals; Behavior, Animal; Betaine; Choline; Dietary Supplements; Female; Folic Acid; Hair Color; Methionine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Selection, Genetic; Species Specificity; Vitamin B 12; Zinc

2009
Are dietary choline and betaine intakes determinants of total homocysteine concentration?
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:5

    Topics: Betaine; Cardiovascular Diseases; Choline; Cognition Disorders; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Vitamin B 12; Vitamin B 6

2010
Subtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet.
    Alcohol (Fayetteville, N.Y.), 2011, Volume: 45, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Betaine; Choline; Diet; DNA Methylation; Drug Resistance; Ethanol; Female; Fetal Death; Fetal Development; Folic Acid; Gene Expression; Genomic Imprinting; Insulin-Like Growth Factor II; Male; Maternal-Fetal Exchange; Methanol; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Species Specificity; Vitamin B 12

2011
Ethanol lowers glutathione in rat liver and brain and inhibits methionine synthase in a cobalamin-dependent manner.
    Alcoholism, clinical and experimental research, 2011, Volume: 35, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Brain; Ethanol; Glutathione; Liver; Male; Rats; Rats, Wistar; Vitamin B 12

2011
Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes.
    Human molecular genetics, 2011, May-01, Volume: 20, Issue:9

    Topics: Animals; Bacteria; Betaine; Choline; Colitis; Dietary Supplements; Disease Susceptibility; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Humans; Intestinal Mucosa; Male; Maternal Nutritional Physiological Phenomena; Metagenome; Mice; Mice, Inbred C57BL; Pedigree; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12

2011
Dietary supplementation with methyl donor groups could prevent nonalcoholic fatty liver.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:6

    Topics: Animals; Betaine; Choline; Dietary Fats; Dietary Sucrose; Dietary Supplements; Disease Models, Animal; Fatty Liver; Folic Acid; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Vitamin B 12

2011
Gestational intake of methyl donors and global LINE-1 DNA methylation in maternal and cord blood: prospective results from a folate-replete population.
    Epigenetics, 2012, Volume: 7, Issue:3

    Topics: Adult; Betaine; Choline; Diet; Dietary Supplements; DNA Methylation; Female; Fetal Blood; Folic Acid; Humans; Infant, Newborn; Long Interspersed Nucleotide Elements; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Vitamin B 12

2012
Maternal intake of methyl-donor nutrients and child cognition at 3 years of age.
    Paediatric and perinatal epidemiology, 2012, Volume: 26, Issue:4

    Topics: Adult; Betaine; Child Development; Child, Preschool; Choline; Cognition; Cohort Studies; Diet; DNA Methylation; Female; Folic Acid; Food; Humans; Massachusetts; Maternal Age; Maternal Nutritional Physiological Phenomena; Methionine; Multivariate Analysis; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prenatal Exposure Delayed Effects; Prospective Studies; Surveys and Questionnaires; Vitamin B 12

2012
Plasma free choline, betaine and cognitive performance: the Hordaland Health Study.
    The British journal of nutrition, 2013, Feb-14, Volume: 109, Issue:3

    Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Diet; Female; Follow-Up Studies; Geriatric Assessment; Humans; Male; Methylmalonic Acid; Norway; Risk Factors; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency

2013
Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.
    The Journal of nutrition, 2013, Volume: 143, Issue:3

    Topics: Animals; Betaine; Choline; Craniofacial Abnormalities; Dietary Supplements; Disease Models, Animal; Face; Female; Folic Acid; Gastrulation; Jaw; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Parity; Pregnancy; Proteins; Risk Factors; Vitamin B 12; Vitamin B Complex

2013
Choline intake during pregnancy and child cognition at age 7 years.
    American journal of epidemiology, 2013, Jun-15, Volume: 177, Issue:12

    Topics: Adult; Betaine; Child; Child Development; Choline; Cognition; Dietary Supplements; Female; Folic Acid; Humans; Intelligence; Male; Massachusetts; Memory; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prenatal Exposure Delayed Effects; Smoking; Socioeconomic Factors; Vitamin B 12

2013
Diet influences expression of autoimmune-associated genes and disease severity by epigenetic mechanisms in a transgenic mouse model of lupus.
    Arthritis and rheumatism, 2013, Volume: 65, Issue:7

    Topics: Animals; Antibodies, Antinuclear; Betaine; CD40 Ligand; Choline; Coenzymes; Diet; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Silencing; Genetic Predisposition to Disease; Lupus Erythematosus, Systemic; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Micronutrients; Riboflavin; Vitamin B 12; Vitamin B 6; Zinc

2013
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
    The American journal of clinical nutrition, 2013, Volume: 97, Issue:6

    Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult

2013
Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.
    The American journal of clinical nutrition, 2013, Volume: 97, Issue:6

    Topics: Adult; Betaine; Choline; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Nutritional Status; Pregnancy; Sarcosine; Spain; Vitamin B 12

2013
[Outcomes of patients with combined methylmalonic acidemia and homocystinuria after treatment].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2013, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Betaine; Carnitine; Child; Child, Preschool; Female; Follow-Up Studies; Homocystine; Homocystinuria; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Male; Methylmalonic Acid; Neonatal Screening; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2013
Low plasma vitamin B-12 is associated with a lower pregnancy-associated rise in plasma free choline in Canadian pregnant women and lower postnatal growth rates in their male infants.
    The American journal of clinical nutrition, 2013, Volume: 98, Issue:5

    Topics: Adult; Betaine; British Columbia; Child Development; Choline; Dietary Supplements; Female; Folic Acid; Humans; Infant; Male; Methionine; Middle Aged; Pregnancy; Prospective Studies; Sarcosine; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2013
Supplementation with methyl donors during lactation to high-fat-sucrose-fed dams protects offspring against liver fat accumulation when consuming an obesogenic diet.
    Journal of developmental origins of health and disease, 2014, Volume: 5, Issue:5

    Topics: Adipose Tissue; Animals; Betaine; Body Composition; Choline; Diet; Diet, High-Fat; Dietary Sucrose; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Female; Folic Acid; Gene Expression; Lactation; Liver; Male; Maternal Nutritional Physiological Phenomena; Obesity; Pregnancy; Rats; Rats, Wistar; Receptors, Leptin; RNA, Messenger; Vitamin B 12

2014
Maternal methyl-enriched diet in rat reduced the audiogenic seizure proneness in progeny.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 127

    Topics: Animals; Animals, Newborn; Betaine; Choline; Diet; Epilepsy, Reflex; Female; Folic Acid; Male; Maternal Welfare; Methionine; Methylation; Pregnancy; Rats; Rats, Wistar; Vitamin B 12

2014
Interactive performances of betaine on the metabolic processes of Pseudomonas denitrificans.
    Journal of industrial microbiology & biotechnology, 2015, Volume: 42, Issue:2

    Topics: Aminolevulinic Acid; Betaine; Fermentation; Glutamic Acid; Glycine; Metabolomics; Methionine; Pseudomonas; Vitamin B 12

2015
Clinical pattern, mutations and in vitro residual activity in 33 patients with severe 5, 10 methylenetetrahydrofolate reductase (MTHFR) deficiency.
    Journal of inherited metabolic disease, 2016, Volume: 39, Issue:1

    Topics: Ataxia; Betaine; Child; Female; Folic Acid; Genetic Association Studies; Homocystinuria; Humans; Intellectual Disability; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Mutation; Phenotype; Psychotic Disorders; Retrospective Studies; Spinal Cord Diseases; Vitamin B 12

2016
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
    Nutrients, 2015, Jun-04, Volume: 7, Issue:6

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6

2015
Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study.
    The American journal of clinical nutrition, 2016, Volume: 104, Issue:5

    Topics: Adipose Tissue; Adolescent; Adult; Betaine; Birth Weight; Body Composition; Body Mass Index; Choline; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Infant; Linear Models; Male; Methionine; Middle Aged; Nutritional Status; Prospective Studies; Sensitivity and Specificity; Singapore; Vitamin B 12; Young Adult

2016
Combined methylmalonic acidemia and homocysteinemia presenting predominantly with late-onset diffuse lung disease: a case series of four patients.
    Orphanet journal of rare diseases, 2017, 03-21, Volume: 12, Issue:1

    Topics: Betaine; Child; Child, Preschool; Female; Folic Acid; Homocystinuria; Humans; Infant; Lung Diseases; Male; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6

2017
Skin lesions in a patient with Cobalamin C disease in poor metabolic control.
    Journal of inherited metabolic disease, 2018, Volume: 41, Issue:2

    Topics: Betaine; Biopsy; Child; Drug Therapy, Combination; Homocystinuria; Humans; Injections; Leucovorin; Male; Medication Adherence; Skin; Skin Diseases; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins; Wound Healing

2018
One-carbon metabolite ratios as functional B-vitamin markers and in relation to colorectal cancer risk.
    International journal of cancer, 2019, 03-01, Volume: 144, Issue:5

    Topics: Betaine; Biomarkers, Tumor; Carbon; Case-Control Studies; Colorectal Neoplasms; Creatinine; Cysteine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Riboflavin; Vitamin B 12; Vitamin B Complex

2019
Fetal one-carbon nutrient concentrations may be affected by gestational diabetes.
    Nutrition research (New York, N.Y.), 2018, Volume: 55

    Topics: Adult; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Fetal Blood; Fetal Development; Fetus; Folic Acid; Humans; Infant, Newborn; Nutrients; Nutritional Status; Pregnancy; Prenatal Care; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2018
Dietary intake of one-carbon metabolism nutrients and DNA methylation in peripheral blood.
    The American journal of clinical nutrition, 2018, 09-01, Volume: 108, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Australia; Betaine; Carbon; Choline; Cross-Sectional Studies; Diet; Diet Records; DNA Methylation; Epigenesis, Genetic; Female; Genome-Wide Association Study; Humans; Male; Methionine; Middle Aged; Nutrients; Riboflavin; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6

2018
One-Carbon Cofactor Intake and Risk of Neural Tube Defects Among Women Who Meet Folic Acid Recommendations: A Multicenter Case-Control Study.
    American journal of epidemiology, 2019, 06-01, Volume: 188, Issue:6

    Topics: Adult; Betaine; Carbon; Case-Control Studies; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Methionine; Neural Tube Defects; Odds Ratio; Pregnancy; Risk Factors; Socioeconomic Factors; United States; Vitamin B 12; Vitamin B 6

2019
A high methyl donor diet affects physiology and behavior in Peromyscus polionotus.
    Physiology & behavior, 2019, 10-01, Volume: 209

    Topics: Absorptiometry, Photon; Animals; Anxiety; Behavior, Animal; Betaine; Choline; Diet; DNA Methylation; Female; Folic Acid; Gonadotropin-Releasing Hormone; Male; Peromyscus; Social Behavior; Vitamin B 12

2019
A diet rich in taurine, cysteine, folate, B
    Medical hypotheses, 2019, Volume: 132

    Topics: Alzheimer Disease; Animals; Betaine; Brain; Cysteine; Diet; Dietary Supplements; Folic Acid; Gases; Humans; Hydrogen Sulfide; Methylation; Risk; Taurine; Vitamin B 12

2019
Adult-onset methylenetetrahydrofolate reductase deficiency.
    BMJ case reports, 2020, Mar-10, Volume: 13, Issue:3

    Topics: Age of Onset; Betaine; Dysarthria; Folic Acid; Gait Ataxia; Homocystinuria; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Psychotic Disorders; Tremor; Vitamin B 12; Young Adult

2020
Low protein diet and methyl-donor supplements modify testicular physiology in mice.
    Reproduction (Cambridge, England), 2020, Volume: 159, Issue:5

    Topics: Animals; Betaine; Choline; Diet, Protein-Restricted; Dietary Supplements; Fatty Acids; Folic Acid; Male; Methionine; Mice; Testis; Vitamin B 12

2020
An unusually high plasma concentration of homocysteine resulting from a combination of so-called "secondary" etiologies.
    Clinical biochemistry, 2020, Volume: 80

    Topics: Aged; Betaine; Female; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Leucovorin; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Psychotic Disorders; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2020
POSITIVE EFFECT OF BETAINE-ARGININE SUPPLEMENT ON IMPROVED HYPERHOMOCYSTEINEMIA TREATMENT IN MARRIED COUPLES WITH REPRODUCTIVE DISORDERS.
    Georgian medical news, 2020, Issue:309

    Topics: Arginine; Betaine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12

2020
Revealing the Promoting Effect of Betaine on Vitamin B
    Current pharmaceutical biotechnology, 2022, Volume: 23, Issue:3

    Topics: Betaine; Biosynthetic Pathways; Proteomics; Pseudomonas; Vitamin B 12; Vitamins

2022
Not a "they" but a "we": The microbiome helps promote our well-being.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:2

    Topics: Betaine; Carnitine; Eubacterium; Gastrointestinal Microbiome; Humans; Methylamines; Methyltransferases; Microbiota; Oxides; Vitamin B 12

2022
Micronutrients of the one-carbon metabolism cycle are altered in mothers and neonates by gestational diabetes and are associated with weight, height and head circumference at birth.
    The Journal of nutritional biochemistry, 2022, Volume: 105

    Topics: Betaine; Birth Weight; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Glycine; Humans; Infant, Newborn; Micronutrients; Mothers; Pregnancy; Tandem Mass Spectrometry; Vitamin B 12

2022
Late-onset cblC deficiency around puberty: a retrospective study of the clinical characteristics, diagnosis, and treatment.
    Orphanet journal of rare diseases, 2022, 09-02, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Betaine; Carnitine; Child; Female; Homocystinuria; Humans; Infant; Male; Mutation; Oxidoreductases; Paraplegia; Puberty; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2022