betaine and trimethyloxamine

betaine has been researched along with trimethyloxamine in 128 studies

Research

Studies (128)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.34)18.7374
1990's6 (4.69)18.2507
2000's18 (14.06)29.6817
2010's60 (46.88)24.3611
2020's41 (32.03)2.80

Authors

AuthorsStudies
Rebouche, CJ1
Chenard, CA; Rebouche, CJ1
Banjac, B; Drewes, LR; Kloiber, O1
Charest, RP; Chenoweth, M; Dunn, A1
Charest, R; Dunn, A1
Guppy, M; Withers, PC1
Burg, MB; Peters, EM2
Overland, M; Rørvik, KA; Skrede, A1
Anderson, CF; Capp, MW; Courtenay, ES; Record, MT1
Ratnaparkhi, GS; Varadarajan, R1
Galinski, EA; Lever, M; Randall, K1
Bottomley, SP; Chow, MK; Devlin, GL1
Ortiz-Costa, S; Sola-Penna, M; Sorenson, MM1
Banerjee, R; Bhattacharyya, A; Lahiri, S; Mandal, AK; Roy, S; Samaddar, S1
Bailey, DM; Kemp, KM; Rhea, MD; Yancey, PH1
Chebotareva, NA; Harding, SE; Kurganov, BI; Winzor, DJ1
Bedford, JJ; Leader, JP; Samuelsson, LM; Smith, RA1
Bell, JD; Chung, YL; Hicks, J; Miller, FW; Passo, MH; Rennebohm, RM; Rider, LG; Scott, DL; Summers, RM; Zemel, LS1
Chebotareva, NA; Eronina, TB; Kurganov, BI1
Di Michele, A; Freda, M; Onori, G; Paolantoni, M; Santucci, A; Sassi, P1
Hegde, ML; Rao, KS1
Draper, DE; Lambert, D1
Olsen, SN; Ramløv, H; Westh, P1
Chebotareva, NA1
Gonnelli, M; Strambini, GB1
Rau, DC; Stanley, C1
Agard, DA; Bolen, DW; Krukenberg, KA; Rosgen, J; Street, TO1
Braverman, N; Chen, L; Jiralerspong, S; Snowden, A; Steinberg, S; Zhang, R1
Barrow, KD; Burns, BP; Goh, F; Neilan, BA1
Borwankar, T; Dosche, C; Ignatova, Z; Röthlein, C; Techen, A; Zhang, G1
Rader, DJ; Rak, K1
Allayee, H; Bennett, BJ; Britt, EB; Chung, YM; DiDonato, JA; Dugar, B; Feldstein, AE; Fu, X; Hazen, SL; Klipfell, E; Koeth, R; Levison, BS; Lusis, AJ; Schauer, P; Smith, JD; Tang, WH; Wang, Z; Wu, Y1
Lenky, CC; Lever, M; McEntyre, CJ1
Erwin, N; Estel, K; Seeliger, J; Winter, R1
Britt, EB; Fu, X; Hazen, SL; Koeth, RA; Levison, BS; Tang, WH; Wang, Z; Wu, Y1
Bruździak, P; Panuszko, A; Stangret, J1
Myers, JK; Silvers, TR1
Dozen, M; Miyawaki, O; Nomura, K1
Bittl, R; Brecht, M; Hussels, M; Nieder, JB1
Britt, EB; Buffa, JA; Fan, Y; Fu, X; Hazen, SL; Koeth, RA; Levison, BS; Tang, WH; Wang, Z; Wu, Y1
Burke, T; Coumoundouros, C; Culham, DE; Deutch, CE; Ellinger, J; Kerr, CH; Murdock, L; Plater, SM; To, E; Wood, JM; Wright, G1
Cirule, H; Dambrova, M; Grinberga, S; Gustina, D; Kuka, J; Liepins, J; Liepinsh, E; Loza, E; Makrecka-Kuka, M; Pugovics, O; Zharkova-Malkova, O1
Bae, S; Bailey, LB; Beresford, SA; Brown, EC; Caudill, MA; Cheng, TY; Cushing-Haugen, KL; Green, R; Lane, DS; Malysheva, O; Miller, JW; Neuhouser, ML; Ulrich, CM; Xiao, L; Zheng, Y1
Aakhus, S; Aukrust, P; Berge, RK; Bjørndal, B; Dahl, CP; Gregersen, I; Gude, E; Gullestad, L; Halvorsen, B; Hov, JR; Karlsen, TH; Svardal, A; Trøseid, M; Ueland, T; Yndestad, A1
Buffa, JA; Culley, MK; DiDonato, JA; Gregory, JC; Hazen, SL; Koeth, RA; Levison, BS; Li, L; Lusis, AJ; Org, E; Smith, JD; Tang, WHW; Wang, Z; Wu, Y1
Borowski, AG; Hazen, SL; Klein, AL; Shrestha, K; Tang, WH; Troughton, RW; Wang, Z; Wu, Y1
Atkinson, W; Bellamy, D; Chambers, ST; Elmslie, JL; Frampton, CM; George, PM; Ho, M; Lever, M; McEntyre, CJ; Molyneux, SL; Richards, AM; Slow, S; Troughton, RW; Young, JM1
Drosos, I; Kolios, G; Tavridou, A1
Nolin, TD; Ocque, AJ; Stubbs, JR1
Singh, LR; Warepam, M1
Dambrova, M; Grinberga, S; Hartmane, D; Konrade, I; Latkovskis, G; Liepinsh, E; Pugovics, O; Sevostjanovs, E; Strele, I1
Berger, H; Caudill, MA; Croxford, R; El-Sohemy, A; Kim, YI; Lausman, AY; Ly, A; Malysheva, O; Masih, S; Nielsen, DE; O'Connor, DL; Plumptre, L; Sohn, KJ; Visentin, CE1
Boutagy, NE; Davy, BM; Davy, KP; Englund, TR; Hulver, MW; Neilson, AP; Osterberg, KL; Smithson, AT2
Allenspach, M; Drexel, H; Mueller, DM; Muendlein, A; Othman, A; Saely, CH; von Eckardstein, A; Vonbank, A1
Berge, RK; Bjørndal, B; Bohov, P; Bruheim, I; Nordrehaug, JE; Ramsvik, MS; Rostrup, E; Svardal, A1
Allenspach, M; Linseisen, J; Müller, D; Rohrmann, S; von Eckardstein, A1
Chen, XL; Chen, YM; Ling, WH; Liu, Y; Tan, XY; Wang, C; Wang, LJ; Zhang, HW; Zheng, RD; Zhou, RF; Zhu, HL1
Barany, P; Bergman, P; Hällqvist, J; Heimbürger, O; Lindholm, B; Missailidis, C; Qureshi, AR; Stenvinkel, P1
Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y1
Abbas, A; Aukrust, P; Berge, RK; Bjerkeli, V; Gregersen, I; Halvorsen, B; Holm, S; Hov, JE; Karlsen, TH; Kummen, M; Reier-Nilsen, F; Russell, D; Skagen, K; Skjelland, M; Svardal, A; Trøseid, M; Ueland, T1
Garringer, M; Qasim, MA1
Berge, RK; Hov, JR; Lappegård, KT; Nestvold, TK; Svardal, A; Thoresen, H; Trøseid, M1
Ferrucci, L; Gonzalez-Freire, M; Maleta, KM; Manary, MJ; Moaddel, R; Ordiz, MI; Semba, RD; Trehan, I; Zhang, P1
Johnson, T; Kaaks, R; Katzke, V; Kühn, T; Müller, D; Rohrmann, S; Sookthai, D; von Eckardstein, A1
Awwad, HM; Geisel, J; Keller, M; Obeid, R1
Fan, Y; Hazen, SL; Li, DS; Li, XS; Tang, WH; Wang, Z; Wu, Y1
Cremer, PS; DeLyser, MR; Liao, YT; Manson, AC; Noid, WG1
Chen, MX; Lu, JQ; Nie, J; Wang, S; Xia, GH; Xu, KY; Yin, J; You, C; Zhen, X; Zhou, HW1
Berge, RK; Haissman, JM; Haugaard, AK; Hov, JR; Nielsen, SD; Ostrowski, SR; Trøseid, M1
Arós, F; Bulló, M; Clish, CB; Corella, D; Dennis, C; Estruch, R; Fiol, M; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wang, DD1
Cai, Y; Hong, W; Huang, M; Jin, J; Li, G; Xiao, C; Xu, C; Yu, W; Zhao, Y; Zhou, Z1
Broniowska, K; Levy, HL; Murali, SG; Nair, N; Ney, DM; Rohr, F; Stroup, BM1
Chmurzynska, A; Malinowska, AM; Mlodzik, MA; Nowacka-Woszuk, J; Radziejewska, A; Szwengiel, A1
Barlik, M; Chmurzynska, A; Drews, K; Jagodziński, PP; Kurzawińska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Szwengiel, A1
Bartlett, D; Cody, DB; Copeland, MF; Culley, MK; Dai, HJ; DiDonato, JA; Fu, X; Garcia-Garcia, JC; Gu, X; Hazen, SL; Kirsop, J; Koeth, RA; Lam-Galvez, BR; Levison, BS; Li, L; Li, XS; Tang, WHW; Wang, Z; Wu, Y1
Miyoshi, D; Moriizumi, Y; Noji, H; Tabata, KV1
Chen, MH; Chen, W; Jiang, XY; Lin, Y; Liu, LL; Luo, X; Niu, JJ; Ren, J; Yan, JH; Yang, TC; Zhuang, JC1
Angiletta, CJ; Baugh, ME; Davy, KP; Djuric, Z; Griffin, LE; Mitchell, CM; Neilson, AP1
Crane, H; Deeks, SG; Drozd, D; Hsue, PY; Hunt, P; Ma, Y; Martin, J; Neilan, BD; Rahalkar, S; Scherzer, R; Sinha, A1
Andreassen, AK; Arora, S; Aukrust, P; Berge, RK; Broch, K; Dellgren, G; Gude, E; Gullestad, L; Hov, JR; Karason, K; Mayerhofer, CCK; Svardal, A; Trøseid, M; Ueland, T1
Cao, YF; Fang, ZZ; Hu, G; Huo, X; Leng, J; Li, J; Li, SN; Li, W; Liu, J; Ma, RCW; Shao, P; Yang, K; Yang, X1
Acikgoz, A; Berge, RK; Bjørndal, B; Caliskan Guzelce, E; Eyupoglu, ND; Svardal, A; Uyanik, E; Yildiz, BO1
Jakovlić, I; Wang, F; Wang, WM; Xu, J; Zhao, YH1
Fudge, DS; Hoang, C; Jain, G; McCord, C; Singh, K; Starksen, M; Yancey, P1
Aguesse, A; Billon-Crossouard, S; Croyal, M; Ene, L; Guebre-Egziabher, F; Juillard, L; Krempf, M; Lemoine, S; Pelletier, CC; Soulage, CO1
Cheng, I; Franke, AA; Fu, BC; Hullar, MAJ; Lampe, JW; Le Marchand, L; Lim, U; Madeleine, MM; Monroe, KR; Randolph, TW; Shepherd, JA; Wilkens, LR1
de Oliveira, TE; Narang, P; Netz, PA; Venkatesu, P1
Butler, LM; Gao, YT; Huang, JY; Jin, A; Koh, WP; Luu, HN; Midttun, Ø; Tan, Y; Ueland, PM; Ulvik, A; Wang, R; Yuan, JM1
Meyer, KA1
Bardagjy, AS; Houts, H; Randolph, JM; Sacchi, R; Sawrey-Kubicek, L; Steinberg, FM; Tang, X; Zhu, C; Zivkovic, AM1
Chi, N; Jiang, XM; Wang, YM; Xue, CH; Yu, ZL; Zhang, LY; Zhang, TT1
García-Cañas, V; Simó, C1
Aguilar-Salinas, C; Campos-Pérez, F; Canizales-Quinteros, S; Gómez-Pérez, F; González-González, I; Grandini-Rosales, P; Hazen, SL; Hernández-Pando, R; Huertas-Vazquez, A; Hui, ST; Larrieta-Carrasco, E; León-Mimila, P; Li, XS; López-Contreras, B; Lusis, AJ; Macías-Kauffer, L; Morán-Ramos, S; Ocampo-Medina, E; Olivares-Arevalo, M; Shih, DM; Villamil-Ramírez, H; Villarreal-Molina, T; Wang, Z1
Chen, L; Chen, Y; Fan, D; Zhao, M; Zheng, L1
Dai, Q; Guo, F; Liu, Y; Ouyang, D; Tan, Z; Zeng, X; Zhang, H1
Emoto, T; Hirata, KI; Yamashita, T; Yoshida, N1
Arnemo, JM; Bergman, P; Bieber, C; Ebert, T; Fröbert, O; Giroud, S; Göritz, F; Johnson, RJ; Kublickiene, K; Painer, J; Qureshi, AR; Redtenbacher, I; Shiels, PG; Stalder, G; Stenvinkel, P; Vetter, S; Zedrosser, A1
Alonso-Gómez, A; Bulló, M; Clish, C; Corella, D; Estruch, R; Fiol, M; Fitó, M; Guasch-Ferré, M; Hernández-Alonso, P; Hu, FB; Li, J; Liang, L; Martínez-González, MA; Papandreou, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Santos-Lozano, JM; Serra-Majem, L; Toledo, E1
Cao, W; Gao, M; Huang, T; Liu, Z; Yang, R; Zhuang, Z1
Herrmann, C; Schnatwinkel, J1
Bernieh, D; Cassambai, S; Heaney, LM; Israr, MZ; Jones, DJL; Ng, LL; Salzano, A; Suzuki, T; Yazaki, Y1
Bahnson, J; Bihlmeyer, N; Chen, H; Ilkayeva, O; Kwee, LC; Laferrère, B; Muehlbauer, MJ; Newgard, CB; Purnell, JQ; Shah, SH; Wolfe, B; Xavier Pi-Sunyer, F1
Duan, XF; Wang, CC; Wang, YM; Xue, CH; Zhang, TT1
Fan, W; Han, L; He, M; Huang, S; Jiang, M; Lei, P; Ren, J; Ren, M; Wang, Y; Yu, H1
Bhat, MY; Dar, TA; Malik, MA; Singh, LR1
Bergman, P; Buchanan, S; Combet, E; Craven, H; Ellaway, A; Galbraith, N; Ijaz, UZ; Jones, B; Mafra, D; McGuinness, D; McGuinness, DH; Shiels, PG; Stenvinkel, P1
Bergström, M; Fagerström, C; Hefni, ME; Lennqvist, T; Witthöft, CM1
He, JQ; Zheng, Y1
Amrein, M; Bakula, A; Ceresa, B; Glarner, N; Haaf, P; Hazen, SL; Honegger, U; Koechlin, L; Leu, K; Li, XS; Mueller, C; Nestelberger, T; Puelacher, C; Schäfer, I; Strebel, I; Twerenbold, R; Walter, J; Wang, Z; Zellweger, M; Zimmermann, T1
Bakker, SJL; Blokzijl, H; Connelly, MA; de Meijer, VE; Dullaart, RPF; Flores-Guerrero, JL; Garcia, E; van den Berg, EH1
Budoff, M; de Oliveira Otto, MC; DiDonato, JA; Fretts, AM; Hazen, SL; Jensen, P; Lai, H; Lee, Y; Lemaitre, RN; Mozaffarian, D; Psaty, BM; Siscovick, DS; Sitlani, CM; Sotoodehnia, N; Tang, WHW; Wang, M1
Harrison, EE; Waters, ML1
Chen, B; Fu, Q; Wei, S; Xiong, X; Xu, X; Yang, S; Zhou, J1
Bubák, D; Dračínský, M; Fagan, P; Ganguly, P; Heyda, J; Polák, J; Shea, JE; van der Vegt, NFA1
Anand, N; Chandana, KA; Chidambaram, SB; Kalyan, M; Kanna, PV; Mahalakshmi, AM; Pandi-Perumal, SR; Praveenraj, SS; Sakharkar, MK; Shasthara, P; Sonali, S; Tousif, HA; Vichitra, C; Yang, J1
Cao, Y; Chang, X; Dai, Y; Guo, J; Liang, W; Lu, D; Lv, S; Qi, X; Wang, Z; Wu, C; Zhang, J; Zhang, L; Zhou, Z1
de Oliveira Otto, MC; Fretts, A; Hazen, SL; Lai, HTM; Lee, Y; Lemaitre, RN; Li, XS; Lopez, O; Mozaffarian, D; Nemet, I; Newman, AB; Siscovick, DS; Tang, WHW; Wang, M; Wang, Z1
Gu, S; Liu, D; Ma, Z; Zhou, Z; Zuo, H1
Arabpour, Z; Hasani, M; Khodabakhshi, A; Monfared, V; Vahid, F1
France, TL; Frost, IR; Javaid, A; McFadden, JW; Myers, WA1
Blanco, R; Daimiel, L; Dávalos, A; Díez-Ricote, L; Micó, V; Ordovás, JM; Ruiz-Valderrey, P; Tomé-Carneiro, J1
Akrofi-Mantey, H; Ascani, M; Cea-Klapp, E; Gajardo-Parra, NF; Garrido, JM; Held, C; Sadowski, G1
Li, R; Liu, R; Wan, Z; Wang, G; Yu, Z; Zhang, Y; Zhang, Z1
Arnold, CD; Beckner, AG; Bennett, BJ; Bragg, MG; Caswell, BL; DeBolt, MC; George, M; Maleta, KM; Oakes, LM; Prado, EL; Stewart, CP1
Bernhard, W; Böckmann, KA; Franz, AR; Minarski, M; Poets, CF; Shunova, A; Wiechers, C1
Ament, Z; Bevers, MB; Bhave, VM; Couch, CA; Garcia Guarniz, AL; Irvin, MR; Kijpaisalratana, N; Kimberly, WT1

Reviews

5 review(s) available for betaine and trimethyloxamine

ArticleYear
Effect of molecular crowding on the enzymes of glycogenolysis.
    Biochemistry. Biokhimiia, 2007, Volume: 72, Issue:13

    Topics: Animals; Betaine; Cytoplasm; Enzymes; Glycogenolysis; Humans; Kinetics; Ligands; Methylamines; Molecular Conformation; Osmosis; Phosphorylase b; Phosphorylase Kinase; Prohibitins; Protein Interaction Mapping; Thermodynamics

2007
New aspects on the metabolic role of intestinal microbiota in the development of atherosclerosis.
    Metabolism: clinical and experimental, 2015, Volume: 64, Issue:4

    Topics: Animals; Atherosclerosis; Betaine; Carnitine; Choline; Humans; Intestinal Mucosa; Intestines; Methylamines; Microbiota; Phosphatidylcholines

2015
Dietary bioactive ingredients to modulate the gut microbiota-derived metabolite TMAO. New opportunities for functional food development.
    Food & function, 2020, Aug-01, Volume: 11, Issue:8

    Topics: Betaine; Biological Availability; Carnitine; Choline; Diet; Food Ingredients; Functional Food; Gastrointestinal Absorption; Gastrointestinal Microbiome; Gastrointestinal Tract; Heart Disease Risk Factors; Humans; Liver; Methylamines; Oxygenases

2020
The Role of a Gut Microbial-Derived Metabolite, Trimethylamine N-Oxide (TMAO), in Neurological Disorders.
    Molecular neurobiology, 2022, Volume: 59, Issue:11

    Topics: Betaine; Carnitine; Choline; Flavins; Gastrointestinal Microbiome; Humans; Inflammasomes; Lyases; Methylamines; Mixed Function Oxygenases; Nervous System Diseases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein

2022
Association between Levels of Trimethylamine N-Oxide and Cancer: A Systematic Review and Meta-Analysis.
    Nutrition and cancer, 2023, Volume: 75, Issue:2

    Topics: Betaine; Choline; Female; Humans; Neoplasms; Risk Factors

2023

Trials

10 trial(s) available for betaine and trimethyloxamine

ArticleYear
Probiotic supplementation and trimethylamine-N-oxide production following a high-fat diet.
    Obesity (Silver Spring, Md.), 2015, Volume: 23, Issue:12

    Topics: Adolescent; Adult; Betaine; Carnitine; Choline; Diet, High-Fat; Dietary Supplements; Fasting; Humans; Male; Methylamines; Probiotics; Tandem Mass Spectrometry; Young Adult

2015
Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study.
    Lipids in health and disease, 2015, Dec-15, Volume: 14

    Topics: Adolescent; Adult; Animals; Atherosclerosis; Betaine; Carnitine; Choline; Chylomicrons; Cytokines; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Eicosapentaenoic Acid; Erythrocytes; Euphausiacea; Fatty Acids, Unsaturated; Female; Humans; Lipoproteins, VLDL; Male; Methylamines; Particle Size; Pilot Projects; Triglycerides

2015
Trimethylamine-N-oxide and its biological variations in vegetarians.
    European journal of nutrition, 2017, Volume: 56, Issue:8

    Topics: Adult; Aged; Betaine; Biomarkers; Diet, Vegetarian; Female; Humans; Male; Methylamines; Middle Aged; Sarcosine; Single-Blind Method; Vegetarians; Vitamin B 12

2017
Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study.
    Journal of the American Heart Association, 2017, Oct-28, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Betaine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Chi-Square Distribution; Choline; Chromatography, Liquid; Diet, Mediterranean; Female; Humans; Incidence; Male; Metabolomics; Methylamines; Middle Aged; Multivariate Analysis; Phospholipid Ethers; Phosphorylcholine; Proportional Hazards Models; Prospective Studies; Risk Factors; Spain; Tandem Mass Spectrometry; Time Factors; Treatment Outcome

2017
Metabolomic Markers of Essential Fatty Acids, Carnitine, and Cholesterol Metabolism in Adults and Adolescents with Phenylketonuria.
    The Journal of nutrition, 2018, 02-01, Volume: 148, Issue:2

    Topics: Adolescent; Adult; Amino Acids; Betaine; Biomarkers; Carnitine; Caseins; Cholesterol; Cross-Over Studies; Dietary Supplements; Erythrocytes; Fasting; Fatty Acids; Fatty Acids, Essential; Female; Gastrointestinal Microbiome; Humans; Lipid Metabolism; Male; Metabolomics; Methylamines; Middle Aged; Peptide Fragments; Phenylketonurias

2018
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
    The Journal of clinical investigation, 2019, 01-02, Volume: 129, Issue:1

    Topics: Animals; Atherosclerosis; Betaine; Carnitine; Clostridiales; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Mice; Pilot Projects; Vegans

2019
A Mediterranean diet does not alter plasma trimethylamine N-oxide concentrations in healthy adults at risk for colon cancer.
    Food & function, 2019, Apr-01, Volume: 10, Issue:4

    Topics: Adult; Aged; Bacteria; Betaine; Choline; Colonic Neoplasms; Diet, Mediterranean; Fasting; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged

2019
Whole egg consumption increases plasma choline and betaine without affecting TMAO levels or gut microbiome in overweight postmenopausal women.
    Nutrition research (New York, N.Y.), 2020, Volume: 78

    Topics: Aged; Bacteria; Betaine; Choline; Cross-Over Studies; Diet; Eggs; Feces; Female; Gastrointestinal Microbiome; Humans; Methylamines; Middle Aged; Obesity; Overweight; Postmenopause

2020
Metabolites and diabetes remission after weight loss.
    Nutrition & diabetes, 2021, 02-24, Volume: 11, Issue:1

    Topics: Amino Acids, Branched-Chain; Bariatric Surgery; Betaine; Biomarkers; Choline; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Methylamines; Middle Aged; Obesity; Obesity, Morbid; Remission Induction; Treatment Outcome; Tyrosine; Weight Loss

2021
Different choline supplement metabolism in adults using deuterium labelling.
    European journal of nutrition, 2023, Volume: 62, Issue:4

    Topics: Adult; Betaine; Choline; Cross-Over Studies; Deuterium; Fatty Acids; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Phosphatidylcholines; Phosphorylcholine; Prospective Studies

2023

Other Studies

113 other study(ies) available for betaine and trimethyloxamine

ArticleYear
Quantitative estimation of absorption and degradation of a carnitine supplement by human adults.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:12

    Topics: Absorption; Administration, Oral; Adult; Betaine; Carnitine; Chromatography, Ion Exchange; Feces; Humans; Male; Methylamines; Scintillation Counting

1991
Metabolic fate of dietary carnitine in human adults: identification and quantification of urinary and fecal metabolites.
    The Journal of nutrition, 1991, Volume: 121, Issue:4

    Topics: Adult; Betaine; Biotransformation; Carnitine; Chromatography, Ion Exchange; Diet; Feces; Humans; Male; Methylamines; Scintillation Counting; Tritium

1991
Protection against acute hyperammonemia: the role of quaternary amines.
    Toxicology, 1988, Volume: 49, Issue:1

    Topics: Acetates; Ammonia; Animals; Betaine; Carnitine; Choline; Glutamates; Glutamic Acid; Glutamine; Male; Methylamines; Mice

1988
Metabolism of trimethylamines in kelp bass (Paralabrax clathratus) and marine and freshwater pink salmon (Oncorhynchus gorbuscha).
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1988, Volume: 158, Issue:5

    Topics: Animals; Bass; Betaine; Choline; Dimethylamines; Liver; Methylamines; Muscles; Perciformes; Radioactive Tracers; Salmon; Water-Electrolyte Balance

1988
Chromatographic separation of choline, trimethylamine, trimethylamine oxide, and betaine from tissues of marine fish.
    Analytical biochemistry, 1984, Volume: 136, Issue:2

    Topics: Animals; Betaine; Carnitine; Choline; Chromatography, Ion Exchange; Fishes; Liver; Methylamines; Muscles; Tissue Extracts

1984
Do Australian desert frogs co-accumulate counteracting solutes with urea during aestivation?
    The Journal of experimental biology, 1996, Volume: 199, Issue:Pt 8

    Topics: Animals; Anura; Australia; Betaine; Body Fluids; Chromatography, High Pressure Liquid; Estivation; Glycerylphosphorylcholine; Inositol; Methylamines; Muscles; Osmolar Concentration; Polymers; Sarcosine; Urea

1996
Urea and methylamines have similar effects on aldose reductase activity.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Aldehyde Reductase; Animals; Betaine; Enzyme Inhibitors; Glycerylphosphorylcholine; Kidney Medulla; Kinetics; Lens, Crystalline; Methylamines; Rats; Recombinant Proteins; Urea

1997
Effects of glycine betaine and glycerophosphocholine on thermal stability of ribonuclease.
    The American journal of physiology, 1998, Volume: 274, Issue:4

    Topics: Animals; Betaine; Cattle; Drug Combinations; Drug Stability; Glycerylphosphorylcholine; Hot Temperature; Methylamines; Ribonuclease, Pancreatic; Urea

1998
Effect of trimethylamine oxide and betaine in swine diets on growth performance, carcass characteristics, nutrient digestibility, and sensory quality of pork.
    Journal of animal science, 1999, Volume: 77, Issue:8

    Topics: Animal Feed; Animals; Betaine; Body Composition; Digestion; Female; Housing, Animal; Lipids; Lipotropic Agents; Male; Meat Products; Methylamines; Oxidants; Random Allocation; Swine

1999
Vapor pressure osmometry studies of osmolyte-protein interactions: implications for the action of osmoprotectants in vivo and for the interpretation of "osmotic stress" experiments in vitro.
    Biochemistry, 2000, Apr-18, Volume: 39, Issue:15

    Topics: Animals; Betaine; Biopolymers; Cattle; Cell Division; Cytoplasm; Dialysis; Escherichia coli; Glutamates; Glycerol; Methylamines; Osmolar Concentration; Pressure; Proline; Serum Albumin; Solutions; Thermodynamics; Trehalose; Water

2000
Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states.
    The Journal of biological chemistry, 2001, Aug-03, Volume: 276, Issue:31

    Topics: Amino Acid Sequence; Betaine; Calorimetry; Crystallography, X-Ray; Enzyme Stability; Methylamines; Models, Molecular; Molecular Sequence Data; Osmolar Concentration; Oxidants; Peptide Fragments; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Ribonuclease, Pancreatic; Ribonucleases; Sarcosine; Taurine; Temperature; Thermodynamics; Trypsin

2001
Near infra-red spectra of urea with glycine betaine or trimethylamine N-oxide are additive.
    Biochimica et biophysica acta, 2001, Oct-03, Volume: 1528, Issue:2-3

    Topics: Betaine; Hydrogen Bonding; Methylamines; Solutions; Spectroscopy, Near-Infrared; Thermodynamics; Urea

2001
Osmolytes as modulators of conformational changes in serpins.
    Biological chemistry, 2001, Volume: 382, Issue:11

    Topics: alpha 1-Antitrypsin; Betaine; Hot Temperature; Humans; Methylamines; Protein Denaturation; Protein Folding; Sarcosine; Serine Proteinase Inhibitors; Serpins; Spectrometry, Fluorescence; Thermodynamics

2001
Counteracting effects of urea and methylamines in function and structure of skeletal muscle myosin.
    Archives of biochemistry and biophysics, 2002, Dec-15, Volume: 408, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Betaine; Fluorescence; Methylamines; Protein Conformation; Protein Structure, Tertiary; Skeletal Muscle Myosins; Urea

2002
Glutamate counteracts the denaturing effect of urea through its effect on the denatured state.
    The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38

    Topics: Amino Acyl-tRNA Synthetases; Animals; Betaine; Carbonic Anhydrases; Cattle; Dose-Response Relationship, Drug; Escherichia coli; Glutamates; Glutamic Acid; Inositol; Kinetics; Methylamines; Oxidants; Potassium Chloride; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Sorbitol; Spectrophotometry; Temperature; Thermodynamics; Time Factors; Trypsin; Tubulin; Urea

2003
Trimethylamine oxide, betaine and other osmolytes in deep-sea animals: depth trends and effects on enzymes under hydrostatic pressure.
    Cellular and molecular biology (Noisy-le-Grand, France), 2004, Volume: 50, Issue:4

    Topics: Adaptation, Physiological; Anemone; Animals; Betaine; Enzyme Stability; Enzymes; Gadiformes; Hydrostatic Pressure; Inositol; Kinetics; L-Lactate Dehydrogenase; Marine Biology; Methylamines; Muscle, Skeletal; Osmolar Concentration; Pyruvate Kinase

2004
Effect of osmolytes on the interaction of flavin adenine dinucleotide with muscle glycogen phosphorylase b.
    Biophysical chemistry, 2005, Jan-01, Volume: 113, Issue:1

    Topics: Animals; Betaine; Flavin-Adenine Dinucleotide; Glycogen Phosphorylase, Muscle Form; Methylamines; Osmolar Concentration; Phosphorylase b; Proline; Protein Binding; Rabbits

2005
A comparison of the counteracting effects of glycine betaine and TMAO on the activity of RNase A in aqueous urea solution.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2005, Volume: 141, Issue:1

    Topics: Animals; Betaine; Catalysis; Cattle; Magnetic Resonance Spectroscopy; Methylamines; Molecular Structure; Ribonuclease, Pancreatic; RNA; Solutions; Urea

2005
Muscle metabolites, detected in urine by proton spectroscopy, correlate with disease damage in juvenile idiopathic inflammatory myopathies.
    Arthritis and rheumatism, 2005, Aug-15, Volume: 53, Issue:4

    Topics: Adolescent; Betaine; Biomarkers; Child; Child, Preschool; Choline; Creatine; Female; Glycine; Humans; Magnetic Resonance Spectroscopy; Male; Methylamines; Muscles; Myositis

2005
Influence of osmolytes on inactivation and aggregation of muscle glycogen phosphorylase b by guanidine hydrochloride. Stimulation of protein aggregation under crowding conditions.
    Biochemistry. Biokhimiia, 2005, Volume: 70, Issue:9

    Topics: Animals; Betaine; Dose-Response Relationship, Drug; Glycine; Glycogen Phosphorylase, Muscle Form; Guanidine; Kinetics; Methylamines; Muscle, Skeletal; Proline; Rabbits

2005
Modulation of hydrophobic effect by cosolutes.
    The journal of physical chemistry. B, 2006, Oct-26, Volume: 110, Issue:42

    Topics: Betaine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Methylamines; Models, Molecular; Spectrum Analysis, Raman; tert-Butyl Alcohol; Water

2006
DNA induces folding in alpha-synuclein: understanding the mechanism using chaperone property of osmolytes.
    Archives of biochemistry and biophysics, 2007, Aug-01, Volume: 464, Issue:1

    Topics: alpha-Synuclein; Animals; Betaine; Cattle; DNA; DNA, Circular; DNA, Single-Stranded; Glycerol; Methylamines; Models, Biological; Molecular Chaperones; Neurodegenerative Diseases; Protein Structure, Secondary; Sarcosine; Taurine

2007
Effects of osmolytes on RNA secondary and tertiary structure stabilities and RNA-Mg2+ interactions.
    Journal of molecular biology, 2007, Jul-27, Volume: 370, Issue:5

    Topics: Base Sequence; Betaine; Cations, Divalent; Ethylene Glycol; Magnesium; Methanol; Methylamines; Molecular Sequence Data; Nucleic Acid Conformation; Osmotic Pressure; Proline; RNA; RNA Stability; Sucrose; Sugar Alcohols; Thermodynamics; Urea

2007
Effects of osmolytes on hexokinase kinetics combined with macromolecular crowding: test of the osmolyte compatibility hypothesis towards crowded systems.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2007, Volume: 148, Issue:2

    Topics: Betaine; Buffers; Catalysis; Fungal Proteins; Glycerol; Hexokinase; Kinetics; Methylamines; Models, Chemical; Osmotic Pressure; Protein Binding; Serum Albumin, Bovine; Sodium Chloride; Urea; Water

2007
Singular efficacy of trimethylamine N-oxide to counter protein destabilization in ice.
    Biochemistry, 2008, Mar-18, Volume: 47, Issue:11

    Topics: Azurin; Betaine; Cysteine; Freeze Drying; Ice; Methylamines; Osmolar Concentration; Oxidants; Protein Denaturation; Protein Folding; Pseudomonas aeruginosa; Sarcosine; Serine; Solutions; Thermodynamics

2008
Measuring the interaction of urea and protein-stabilizing osmolytes with the nonpolar surface of hydroxypropylcellulose.
    Biochemistry, 2008, Jun-24, Volume: 47, Issue:25

    Topics: Algorithms; Betaine; Cellulose; Glycerol; Hydrophobic and Hydrophilic Interactions; Methylamines; Models, Chemical; Organic Chemicals; Osmotic Pressure; Proteins; Scattering, Radiation; Sorbitol; Temperature; Thermodynamics; Urea; X-Rays

2008
Osmolyte-induced conformational changes in the Hsp90 molecular chaperone.
    Protein science : a publication of the Protein Society, 2010, Volume: 19, Issue:1

    Topics: Adenylyl Imidodiphosphate; Betaine; Escherichia coli Proteins; Glycerol; HSP90 Heat-Shock Proteins; Methylamines; Models, Molecular; Osmosis; Protein Conformation; Sarcosine; Scattering, Small Angle; Urea; X-Ray Diffraction

2010
Recovery of PEX1-Gly843Asp peroxisome dysfunction by small-molecule compounds.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Mar-23, Volume: 107, Issue:12

    Topics: Adenosine Triphosphatases; Amino Acid Substitution; ATPases Associated with Diverse Cellular Activities; Betaine; Cells, Cultured; Drug Evaluation, Preclinical; Genes, Reporter; Glycerol; Green Fluorescent Proteins; Humans; Membrane Proteins; Methylamines; Mutation, Missense; Peroxisome-Targeting Signal 1 Receptor; Peroxisomes; Protein Folding; Receptors, Cytoplasmic and Nuclear; Zellweger Syndrome

2010
Identification and regulation of novel compatible solutes from hypersaline stromatolite-associated cyanobacteria.
    Archives of microbiology, 2010, Volume: 192, Issue:12

    Topics: Adaptation, Physiological; Betaine; Culture Media; Cyanobacteria; Ecosystem; Glucosides; Magnetic Resonance Spectroscopy; Methylamines; Salinity; Western Australia

2010
Natural osmolytes remodel the aggregation pathway of mutant huntingtin exon 1.
    Biochemistry, 2011, Mar-29, Volume: 50, Issue:12

    Topics: Animals; Betaine; Biological Products; Exons; Methylamines; Mutant Proteins; Mutation; Nerve Tissue Proteins; Osmosis; Peptides; Proline; Protein Multimerization; Protein Structure, Quaternary; Solubility

2011
Cardiovascular disease: the diet-microbe morbid union.
    Nature, 2011, Apr-07, Volume: 472, Issue:7341

    Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Choline; Diet; Dietary Fats; Gastrointestinal Tract; Humans; Liver; Metabolomics; Methylamines; Mice; Oxygenases; Phosphatidylcholines; Probiotics; Risk Assessment

2011
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
    Nature, 2011, Apr-07, Volume: 472, Issue:7341

    Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; Diet; Dietary Fats; Female; Gastrointestinal Tract; Gene Expression Regulation; Germ-Free Life; Humans; Liver; Macrophages; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Oxygenases; Phenotype; Phosphatidylcholines; Receptors, Scavenger; Risk Assessment

2011
Measurement of marine osmolytes in mammalian serum by liquid chromatography-tandem mass spectrometry.
    Analytical biochemistry, 2012, Jan-01, Volume: 420, Issue:1

    Topics: Animals; Arsenicals; Betaine; Biomarkers; Caniformia; Cattle; Chromatography, Liquid; Limit of Detection; Mammals; Marine Biology; Methylamines; Osmotic Pressure; Picolinic Acids; Plasma; Sensitivity and Specificity; Sulfonium Compounds; Tandem Mass Spectrometry

2012
Cosolvent effects on the fibrillation reaction of human IAPP.
    Physical chemistry chemical physics : PCCP, 2013, Jun-21, Volume: 15, Issue:23

    Topics: Amyloid; Betaine; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Methylamines; Protein Stability; Protein Structure, Secondary; Urea

2013
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk.
    The New England journal of medicine, 2013, Apr-25, Volume: 368, Issue:17

    Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Betaine; Cardiovascular Diseases; Choline; Female; Humans; Intestinal Mucosa; Intestines; Kaplan-Meier Estimate; Male; Metagenome; Methylamines; Middle Aged; Phosphatidylcholines; Prospective Studies; Risk Factors

2013
Influence of osmolytes on protein and water structure: a step to understanding the mechanism of protein stabilization.
    The journal of physical chemistry. B, 2013, Oct-03, Volume: 117, Issue:39

    Topics: Amines; Amino Acids; Animals; Betaine; Calorimetry; Chickens; Egg Proteins; Female; Glycine; Methylamines; Muramidase; Oxygen; Protein Denaturation; Protein Stability; Protein Structure, Secondary; Sarcosine; Solutions; Spectroscopy, Fourier Transform Infrared; Transition Temperature; Water

2013
Osmolyte effects on the self-association of concanavalin A: testing theoretical models.
    Biochemistry, 2013, Dec-23, Volume: 52, Issue:51

    Topics: Betaine; Circular Dichroism; Concanavalin A; Dimerization; Hydrogen-Ion Concentration; Indicators and Reagents; Methylamines; Models, Molecular; Osmolar Concentration; Proline; Protein Interaction Domains and Motifs; Protein Stability; Sarcosine; Secondary Metabolism; Sorbitol; Sucrose; Thermodynamics; Titrimetry; Trehalose; Urea

2013
Thermodynamic analysis of osmolyte effect on thermal stability of ribonuclease A in terms of water activity.
    Biophysical chemistry, 2014, Volume: 185

    Topics: Animals; Betaine; Cattle; Enzyme Stability; Glycine; Inositol; Methylamines; Osmolar Concentration; Proline; Protein Unfolding; Ribonuclease, Pancreatic; Sarcosine; Taurine; Thermodynamics; Water

2014
Effect of TMAO and betaine on the energy landscape of photosystem I.
    Biochimica et biophysica acta, 2014, Volume: 1837, Issue:6

    Topics: Betaine; Kinetics; Methylamines; Photosystem I Protein Complex; Spectrometry, Fluorescence; Synechococcus

2014
Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide.
    European heart journal, 2014, Volume: 35, Issue:14

    Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Female; Humans; Intestinal Mucosa; Kaplan-Meier Estimate; Male; Methylamines; Mice; Microbiota; Middle Aged; Prognosis; Prospective Studies; Risk Assessment; Risk Factors

2014
Analysis of strains lacking known osmolyte accumulation mechanisms reveals contributions of osmolytes and transporters to protection against abiotic stress.
    Applied and environmental microbiology, 2014, Volume: 80, Issue:17

    Topics: Betaine; Culture Media; Escherichia coli; Methylamines; Osmotic Pressure; Proline; Sodium Chloride; Stress, Physiological; Sulfonium Compounds; Temperature; Urea

2014
Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.
    Life sciences, 2014, Nov-11, Volume: 117, Issue:2

    Topics: Animals; Betaine; Biosynthetic Pathways; Carbon Isotopes; Carnitine; Choline; Chromatography, High Pressure Liquid; Gastrointestinal Tract; Methylamines; Methylhydrazines; Microbiota; Rats; Rats, Wistar; Statistics, Nonparametric; Tandem Mass Spectrometry

2014
Plasma choline metabolites and colorectal cancer risk in the Women's Health Initiative Observational Study.
    Cancer research, 2014, Dec-15, Volume: 74, Issue:24

    Topics: Aged; Betaine; Choline; Colorectal Neoplasms; Female; Humans; Methylamines; Middle Aged; Risk Factors; Women's Health

2014
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure.
    Journal of internal medicine, 2015, Volume: 277, Issue:6

    Topics: Aged; Betaine; Biomarkers; Choline; Chronic Disease; Female; Heart Failure; Humans; Intestinal Mucosa; Intestines; Lipotropic Agents; Male; Methylamines; Microbiota; Middle Aged; Oxidants; Predictive Value of Tests; Prognosis; Prospective Studies; Risk Assessment; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Survival Analysis

2015
γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO.
    Cell metabolism, 2014, Nov-04, Volume: 20, Issue:5

    Topics: Animals; Atherosclerosis; Betaine; Carnitine; Female; Gastrointestinal Tract; Methylamines; Mice; Mice, Inbred C57BL; Microbiota

2014
Intestinal microbiota-dependent phosphatidylcholine metabolites, diastolic dysfunction, and adverse clinical outcomes in chronic systolic heart failure.
    Journal of cardiac failure, 2015, Volume: 21, Issue:2

    Topics: Adult; Aged; Betaine; Biomarkers; Blood Pressure; Choline; Chronic Disease; Cohort Studies; Female; Heart Failure, Systolic; Humans; Intestinal Mucosa; Male; Methylamines; Microbiota; Middle Aged; Phosphatidylcholines; Prospective Studies; Risk Factors; Treatment Outcome

2015
Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Betaine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Kaplan-Meier Estimate; Male; Methylamines; Middle Aged; Proportional Hazards Models; Risk Factors

2014
Development and validation of a simple UHPLC-MS/MS method for the simultaneous determination of trimethylamine N-oxide, choline, and betaine in human plasma and urine.
    Journal of pharmaceutical and biomedical analysis, 2015, May-10, Volume: 109

    Topics: Betaine; Calibration; Choline; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Kidney Diseases; Mass Spectrometry; Methylamines; Pilot Projects; Quality Control; Reference Standards; Reproducibility of Results

2015
Osmolyte mixtures have different effects than individual osmolytes on protein folding and functional activity.
    Archives of biochemistry and biophysics, 2015, May-01, Volume: 573

    Topics: Betaine; Cytosine Nucleotides; Enzyme Stability; Hydrolysis; Methylamines; Osmolar Concentration; Protein Folding; Protein Refolding; Ribonuclease, Pancreatic; Sarcosine; Sorbitol; Thermodynamics

2015
Determination of trimethylamine-N-oxide in combination with L-carnitine and γ-butyrobetaine in human plasma by UPLC/MS/MS.
    Biomedical chromatography : BMC, 2015, Volume: 29, Issue:11

    Topics: Betaine; Carnitine; Chromatography, Liquid; Humans; Limit of Detection; Methylamines; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry

2015
Maternal Choline Status, but Not Fetal Genotype, Influences Cord Plasma Choline Metabolite Concentrations.
    The Journal of nutrition, 2015, Volume: 145, Issue:7

    Topics: Adolescent; Adult; Betaine; Canada; Choline; Female; Fetal Blood; Fetus; Genotype; Healthy Volunteers; Humans; Maternal Nutritional Physiological Phenomena; Methylamines; Middle Aged; Polymorphism, Single Nucleotide; Pregnancy; Prospective Studies; Sarcosine; Surveys and Questionnaires; Young Adult

2015
Short-term high-fat diet increases postprandial trimethylamine-N-oxide in humans.
    Nutrition research (New York, N.Y.), 2015, Volume: 35, Issue:10

    Topics: Adolescent; Adult; Betaine; Carnitine; Choline; Diet, Atherogenic; Diet, High-Fat; Fasting; Gastrointestinal Microbiome; Humans; Male; Methylamines; Oxidants; Postprandial Period; Young Adult

2015
Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control.
    Atherosclerosis, 2015, Volume: 243, Issue:2

    Topics: Aged; Betaine; Biomarkers; Blood Glucose; Choline; Chromatography, Liquid; Coronary Angiography; Coronary Disease; Diabetes Mellitus; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Metabolic Syndrome; Methylamines; Middle Aged; Predictive Value of Tests; Prognosis; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Time Factors

2015
Plasma Concentrations of Trimethylamine-N-oxide Are Directly Associated with Dairy Food Consumption and Low-Grade Inflammation in a German Adult Population.
    The Journal of nutrition, 2016, Volume: 146, Issue:2

    Topics: Adult; Animals; Betaine; C-Reactive Protein; Choline; Dairy Products; Diet; Diet Surveys; Feeding Behavior; Female; Germany; Humans; Inflammation; Interleukin-6; Male; Methylamines; Middle Aged; Milk; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha

2016
Associations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults.
    Scientific reports, 2016, Jan-08, Volume: 6

    Topics: Adolescent; Adult; Aged; Betaine; Biomarkers; Case-Control Studies; Choline; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Non-alcoholic Fatty Liver Disease; Severity of Illness Index; Tandem Mass Spectrometry; Ultrasonography

2016
Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Adult; Aged; Betaine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Choline; Female; Fibrinogen; Glomerular Filtration Rate; Humans; Inflammation; Interleukin-6; Kidney Transplantation; Longitudinal Studies; Male; Methylamines; Middle Aged; Multivariate Analysis; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic; Severity of Illness Index; Survival Analysis

2016
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:3

    Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors

2016
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis.
    Atherosclerosis, 2016, Volume: 247

    Topics: Aged; Betaine; Biomarkers; Carnitine; Carotid Stenosis; Case-Control Studies; Cause of Death; Chromatography, High Pressure Liquid; Female; Humans; Kaplan-Meier Estimate; Lysine; Male; Methylamines; Middle Aged; Myocardial Infarction; Prognosis; Proportional Hazards Models; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Ultrasonography, Doppler, Color

2016
Effect of Osmolytes and Guanidinium Chloride on the Enzymatic Properties of Bovine α-Chymotrypsin.
    Protein and peptide letters, 2016, Volume: 23, Issue:6

    Topics: Animals; Betaine; Biocatalysis; Catalytic Domain; Cattle; Chymotrypsin; Guanidine; Kinetics; Methylamines; Peptides; Urea

2016
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery.
    Metabolic syndrome and related disorders, 2016, Volume: 14, Issue:4

    Topics: Adult; Atherosclerosis; Bariatric Surgery; Betaine; Body Mass Index; Cardiovascular Diseases; Carnitine; Case-Control Studies; Choline; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Life Style; Male; Methylamines; Microbiota; Middle Aged; Obesity; Postoperative Period; Time Factors

2016
The association of serum choline with linear growth failure in young children from rural Malawi.
    The American journal of clinical nutrition, 2016, Volume: 104, Issue:1

    Topics: Betaine; Child, Preschool; Choline; Chromatography, Liquid; Cross-Sectional Studies; Diet; Female; Growth; Growth Disorders; Humans; Infant; Malawi; Male; Mass Spectrometry; Methylamines; Nutritional Status; Risk Factors; Rural Population

2016
Intra-individual variation of plasma trimethylamine-N-oxide (TMAO), betaine and choline over 1 year.
    Clinical chemistry and laboratory medicine, 2017, Feb-01, Volume: 55, Issue:2

    Topics: Aged; Aged, 80 and over; Betaine; Choline; Chromatography, Liquid; Female; Humans; Male; Mass Spectrometry; Methylamines; Middle Aged; Time Factors

2017
Increased Trimethylamine N-Oxide Portends High Mortality Risk Independent of Glycemic Control in Patients with Type 2 Diabetes Mellitus.
    Clinical chemistry, 2017, Volume: 63, Issue:1

    Topics: Aged; Betaine; Blood Glucose; Choline; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Methylamines; Middle Aged; Prospective Studies; Risk Factors; Survival Rate

2017
Trimethylamine
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 03-07, Volume: 114, Issue:10

    Topics: Air; Betaine; Elastin; Glycine; Hydrophobic and Hydrophilic Interactions; Methylamines; Molecular Dynamics Simulation; Osmotic Pressure; Peptides; Protein Folding; Solutions; Surface Tension; Water

2017
Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients.
    Scientific reports, 2017, 05-03, Volume: 7, Issue:1

    Topics: Adult; Aged; Animals; Betaine; Carnitine; Case-Control Studies; Choline; Clostridiaceae; Dysbiosis; Fecal Microbiota Transplantation; Female; Gammaproteobacteria; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Humans; Kidney Function Tests; Male; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Renal Insufficiency, Chronic

2017
Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection.
    BMC infectious diseases, 2017, 06-23, Volume: 17, Issue:1

    Topics: Adult; Betaine; Biomarkers; Blood Platelets; Cardiovascular Diseases; Carnitine; Choline; Cross-Sectional Studies; Female; HIV Infections; Humans; Lipopolysaccharide Receptors; Male; Methylamines; Microbiota; Middle Aged; Monocytes; Myocardial Infarction; Platelet Aggregation; Risk Factors

2017
Simultaneous determination of trimethylamine N-oxide, choline, betaine by UPLC-MS/MS in human plasma: An application in acute stroke patients.
    Journal of pharmaceutical and biomedical analysis, 2018, Apr-15, Volume: 152

    Topics: Aged; Betaine; Choline; Chromatography, High Pressure Liquid; Female; Humans; Male; Methylamines; Plasma; Reproducibility of Results; Sensitivity and Specificity; Stroke; Tandem Mass Spectrometry

2018
Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model.
    Biochimie, 2018, Volume: 152

    Topics: Animals; Betaine; Caloric Restriction; Carbon; Choline; DNA Methylation; Female; Gene Expression; Homocysteine; Hydrolases; Liver; Male; Methylamines; Models, Biological; Pregnancy; Pregnancy, Animal; Rats, Wistar; S-Adenosylmethionine

2018
PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women.
    Nutrition research (New York, N.Y.), 2018, Volume: 56

    Topics: Adolescent; Adult; Alleles; Betaine; Birth Weight; Carnitine; Choline; Choline-Phosphate Cytidylyltransferase; Diet; Female; Folic Acid; Genotype; Homozygote; Humans; Infant, Newborn; Methylamines; Nutritional Status; Phosphatidylethanolamine N-Methyltransferase; Poland; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Young Adult

2018
Osmolyte-Enhanced Protein Synthesis Activity of a Reconstituted Translation System.
    ACS synthetic biology, 2019, 03-15, Volume: 8, Issue:3

    Topics: Bacterial Proteins; beta-Galactosidase; Betaine; Cell-Free System; Gene Expression Regulation; Luminescent Proteins; Methylamines; Plasmids; Protein Biosynthesis; Protein Folding; RNA, Messenger; Synthetic Biology; Temperature; Tetrahydrofolate Dehydrogenase; Transcription, Genetic

2019
Analysis of serum metabolite profiles in syphilis patients by untargeted metabolomics.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2019, Volume: 33, Issue:7

    Topics: Acetylcarnitine; Arginine; Betaine; Biomarkers; Case-Control Studies; Female; Humans; Male; Metabolic Networks and Pathways; Metabolomics; Methylamines; Middle Aged; Principal Component Analysis; Syphilis

2019
Carnitine Is Associated With Atherosclerotic Risk and Myocardial Infarction in HIV -Infected Adults.
    Journal of the American Heart Association, 2019, 05-07, Volume: 8, Issue:9

    Topics: Adult; Antiretroviral Therapy, Highly Active; Atherosclerosis; Betaine; Carnitine; Carotid Artery Diseases; Carotid Intima-Media Thickness; Choline; Female; Gastrointestinal Microbiome; HIV Infections; Humans; Male; Methylamines; Middle Aged; Myocardial Infarction; Plaque, Atherosclerotic; Sustained Virologic Response; United States

2019
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2019, Volume: 38, Issue:10

    Topics: Acute Disease; Adult; Aged; Betaine; Carnitine; Coronary Artery Disease; Cyclosporine; Everolimus; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Methylamines; Microbiota; Middle Aged; Postoperative Complications

2019
Trimethylamine N-Oxide Metabolites in Early Pregnancy and Risk of Gestational Diabetes: A Nested Case-Control Study.
    The Journal of clinical endocrinology and metabolism, 2019, 11-01, Volume: 104, Issue:11

    Topics: Adult; Betaine; Blood Glucose; Carnitine; Case-Control Studies; China; Choline; Diabetes, Gestational; Female; Humans; Methylamines; Pregnancy; Prenatal Care; Risk Factors

2019
Circulating gut microbiota metabolite trimethylamine N-oxide and oral contraceptive use in polycystic ovary syndrome.
    Clinical endocrinology, 2019, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Betaine; Blood Glucose; Cardiovascular Diseases; Carnitine; Choline; Female; Gastrointestinal Microbiome; Humans; Methylamines; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Risk Factors; Testosterone; Young Adult

2019
Dietary betaine reduces liver lipid accumulation via improvement of bile acid and trimethylamine-N-oxide metabolism in blunt-snout bream.
    Food & function, 2019, Oct-16, Volume: 10, Issue:10

    Topics: Animal Feed; Animals; Bacteria; Betaine; Bile Acids and Salts; Cyprinidae; Gastrointestinal Microbiome; Liver; Methylamines

2019
High concentrations of trimethylamines in slime glands inhibit skein unraveling in Pacific hagfish.
    The Journal of experimental biology, 2019, 11-22, Volume: 222, Issue:Pt 22

    Topics: Adhesives; Animals; Betaine; Hagfishes; Methylamines; Mucus; Sarcosine; Seawater

2019
Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate.
    Toxins, 2019, 11-01, Volume: 11, Issue:11

    Topics: Adult; Betaine; Choline; Creatinine; Female; Gastrointestinal Microbiome; Glomerular Filtration Rate; Humans; Male; Metabolic Clearance Rate; Methylamines; Middle Aged; Prospective Studies; Renal Dialysis; Renal Insufficiency, Chronic

2019
Associations of plasma trimethylamine N-oxide, choline, carnitine, and betaine with inflammatory and cardiometabolic risk biomarkers and the fecal microbiome in the Multiethnic Cohort Adiposity Phenotype Study.
    The American journal of clinical nutrition, 2020, 06-01, Volume: 111, Issue:6

    Topics: Adiposity; Aged; Bacteria; Betaine; Biomarkers; Cardiovascular Diseases; Carnitine; Choline; Cohort Studies; Cross-Sectional Studies; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged

2020
The role of osmolytes in the temperature-triggered conformational transition of poly(N-vinylcaprolactam): an experimental and computational study.
    Physical chemistry chemical physics : PCCP, 2020, Mar-04, Volume: 22, Issue:9

    Topics: Betaine; Caprolactam; Hydrophobic and Hydrophilic Interactions; Methylamines; Molecular Conformation; Molecular Dynamics Simulation; Phase Transition; Polymers; Sarcosine; Transition Temperature; Water

2020
A prospective evaluation of serum methionine-related metabolites in relation to pancreatic cancer risk in two prospective cohort studies.
    International journal of cancer, 2020, 10-01, Volume: 147, Issue:7

    Topics: Betaine; Case-Control Studies; Choline; Female; Humans; Male; Methionine; Methylamines; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Prospective Studies; Risk Factors

2020
Population studies of TMAO and its precursors may help elucidate mechanisms.
    The American journal of clinical nutrition, 2020, 06-01, Volume: 111, Issue:6

    Topics: Adiposity; Betaine; Biomarkers; Cardiovascular Diseases; Carnitine; Choline; Humans; Methylamines; Microbiota; Phenotype

2020
Effects of dietary choline, betaine, and L-carnitine on the generation of trimethylamine-N-oxide in healthy mice.
    Journal of food science, 2020, Volume: 85, Issue:7

    Topics: Animals; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Intestines; Male; Methylamines; Mice; Mice, Inbred BALB C

2020
Trimethylamine N-oxide levels are associated with NASH in obese subjects with type 2 diabetes.
    Diabetes & metabolism, 2021, Volume: 47, Issue:2

    Topics: Adult; Betaine; Bile Acids and Salts; Biomarkers; Biopsy; Choline; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Liver; Male; Methylamines; Mexican Americans; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity

2021
Changes in the concentrations of trimethylamine N-oxide (TMAO) and its precursors in patients with amyotrophic lateral sclerosis.
    Scientific reports, 2020, 09-16, Volume: 10, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Motor Neurons; Prognosis; Signal Transduction

2020
Renal function is associated with plasma trimethylamine-N-oxide, choline, L-carnitine and betaine: a pilot study.
    International urology and nephrology, 2021, Volume: 53, Issue:3

    Topics: Betaine; Biomarkers; Carnitine; Choline; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Methylamines; Middle Aged; Pilot Projects; Renal Insufficiency, Chronic; Retrospective Studies

2021
Unraveling the Effects of Trimethylamine N-Oxide on Stroke: "The lower, the better?"
    Journal of atherosclerosis and thrombosis, 2021, Apr-01, Volume: 28, Issue:4

    Topics: Betaine; Carnitine; Cholesterol; Choline; Diet Therapy; Gastrointestinal Microbiome; Humans; Ischemic Stroke; Lipotropic Agents; Liver; Methylamines; Oxidants; Risk Factors

2021
Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears.
    Scientific reports, 2020, 11-23, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Betaine; Biomimetics; Cardiovascular Diseases; Choline; Female; Gastrointestinal Microbiome; Hibernation; Humans; Lions; Male; Methylamines; Middle Aged; Myoxidae; Prospective Studies; Renal Insufficiency, Chronic; Sus scrofa; Tigers; Ursidae

2020
Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study.
    Clinical chemistry, 2021, 01-08, Volume: 67, Issue:1

    Topics: Aged; Atrial Fibrillation; Betaine; Carnitine; Case-Control Studies; Choline; Female; Heart Failure; Humans; Male; Methylamines; Prospective Studies; Risk Factors; Sarcosine

2021
Causal relationships between gut metabolites and Alzheimer's disease: a bidirectional Mendelian randomization study.
    Neurobiology of aging, 2021, Volume: 100

    Topics: Alzheimer Disease; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Genetic Predisposition to Disease; Humans; Male; Mendelian Randomization Analysis; Methylamines; Negative Results; Risk

2021
The interaction strength of an intrinsically disordered protein domain with its binding partner is little affected by very different cosolutes.
    Physical chemistry chemical physics : PCCP, 2020, Dec-16, Volume: 22, Issue:47

    Topics: Betaine; CREB-Binding Protein; Entropy; Glycine; Humans; Intrinsically Disordered Proteins; Kinetics; Methylamines; Protein Binding; Protein Domains; Proto-Oncogene Proteins c-myb; Temperature; Urea

2020
Association of gut-related metabolites with outcome in acute heart failure.
    American heart journal, 2021, Volume: 234

    Topics: Acetylcarnitine; Acute Disease; Aged; Aged, 80 and over; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Heart Failure; Hospital Mortality; Humans; Male; Methylamines; Natriuretic Peptide, Brain; Risk Factors; Statistics, Nonparametric

2021
Trimethylamine
    Journal of agricultural and food chemistry, 2021, Mar-17, Volume: 69, Issue:10

    Topics: Betaine; Choline; Methylamines; Molecular Structure

2021
Determination of Trimethylamine
    Molecules (Basel, Switzerland), 2021, Mar-02, Volume: 26, Issue:5

    Topics: Animals; Betaine; Female; Food Analysis; Male; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Oxides; Rats; Rats, Wistar

2021
Trimethylamine N-oxide alters structure-function integrity of β-casein: Structural disorder co-regulates the aggregation propensity and chaperone activity.
    International journal of biological macromolecules, 2021, Jul-01, Volume: 182

    Topics: Betaine; Caseins; Intrinsically Disordered Proteins; Methylamines; Molecular Chaperones; Protein Multimerization; Protein Stability; Sarcosine

2021
Socioeconomic position links circulatory microbiota differences with biological age.
    Scientific reports, 2021, 06-16, Volume: 11, Issue:1

    Topics: Adult; Aged; Aging; Bacteria; Betaine; Female; Humans; Life Style; Male; Methylamines; Middle Aged; Phylogeny; Prospective Studies; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Socioeconomic Factors

2021
Simultaneous quantification of trimethylamine N-oxide, trimethylamine, choline, betaine, creatinine, and propionyl-, acetyl-, and L-carnitine in clinical and food samples using HILIC-LC-MS.
    Analytical and bioanalytical chemistry, 2021, Volume: 413, Issue:21

    Topics: Betaine; Carnitine; Choline; Chromatography, Liquid; Creatinine; Female; Food Analysis; Humans; Limit of Detection; Male; Methylamines; Middle Aged; Tandem Mass Spectrometry

2021
Pathogenic Mechanisms of Trimethylamine N-Oxide-induced Atherosclerosis and Cardiomyopathy.
    Current vascular pharmacology, 2022, Volume: 20, Issue:1

    Topics: Animals; Atherosclerosis; Betaine; Cardiomyopathies; Cardiovascular Diseases; Humans; Methylamines

2022
Gut microbiota-dependent metabolite trimethylamine N-oxide (TMAO) and cardiovascular risk in patients with suspected functionally relevant coronary artery disease (fCAD).
    Clinical research in cardiology : official journal of the German Cardiac Society, 2022, Volume: 111, Issue:6

    Topics: Betaine; Cardiovascular Diseases; Carnitine; Choline; Coronary Artery Disease; Gastrointestinal Microbiome; Heart Disease Risk Factors; Humans; Methylamines; Risk Factors

2022
High plasma levels of betaine, a trimethylamine N-Oxide-related metabolite, are associated with the severity of cirrhosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:2

    Topics: Betaine; Biomarkers; Cohort Studies; End Stage Liver Disease; Humans; Liver Cirrhosis; Severity of Illness Index

2023
Association of Trimethylamine N-Oxide and Metabolites With Mortality in Older Adults.
    JAMA network open, 2022, 05-02, Volume: 5, Issue:5

    Topics: Aged; Betaine; Cardiovascular Diseases; Carnitine; Choline; Cohort Studies; Female; Humans; Male; Methylamines; Prospective Studies

2022
Application of an Imprint-and-Report Sensor Array for Detection of the Dietary Metabolite Trimethylamine N-Oxide and Its Precursors in Complex Mixtures.
    Angewandte Chemie (International ed. in English), 2022, 08-15, Volume: 61, Issue:33

    Topics: Betaine; Choline; Complex Mixtures; Humans; Methylamines

2022
The associations between TMAO-related metabolites and blood lipids and the potential impact of rosuvastatin therapy.
    Lipids in health and disease, 2022, Jul-21, Volume: 21, Issue:1

    Topics: Atherosclerosis; Betaine; Carnitine; Cholesterol, LDL; Choline; Humans; Lipids; Methylamines; Rosuvastatin Calcium; Tandem Mass Spectrometry

2022
Cosolvent Exclusion Drives Protein Stability in Trimethylamine
    The journal of physical chemistry letters, 2022, Sep-01, Volume: 13, Issue:34

    Topics: Betaine; Methylamines; Muramidase; Protein Stability; Ribonuclease T1; Solutions; Thermodynamics; Water

2022
Multiple mediation effects on association between prenatal triclosan exposure and birth outcomes.
    Environmental research, 2022, Volume: 215, Issue:Pt 1

    Topics: Acetylcarnitine; Bayes Theorem; Betaine; Choline; Cohort Studies; Estradiol; Female; Humans; Leptin; Maternal Exposure; Methylamines; Oxides; Pregnancy; Testosterone; Thyroid Hormones; Thyroxine; Triclosan

2022
Longitudinal Associations of Plasma TMAO and Related Metabolites with Cognitive Impairment and Dementia in Older Adults: The Cardiovascular Health Study.
    Journal of Alzheimer's disease : JAD, 2022, Volume: 89, Issue:4

    Topics: Animals; Betaine; Carnitine; Choline; Cognitive Dysfunction; Dementia; Medicare; Methylamines; United States

2022
Associations of plasma TMAO and its precursors with stroke risk in the general population: A nested case-control study.
    Journal of internal medicine, 2023, Volume: 293, Issue:1

    Topics: Betaine; Carnitine; Case-Control Studies; Choline; Humans; Stroke

2023
Changes in plasma and milk choline metabolite concentrations in response to the provision of various rumen-protected choline prototypes in lactating dairy cows.
    Journal of dairy science, 2022, Volume: 105, Issue:12

    Topics: Animal Feed; Animals; Betaine; Cattle; Choline; Diet; Dietary Supplements; Female; Lactation; Milk; Rumen

2022
TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis.
    International journal of molecular sciences, 2022, Oct-11, Volume: 23, Issue:20

    Topics: Animals; Atherosclerosis; Betaine; Cardiovascular Diseases; Carnitine; Choline; Humans; Inflammation; Methylamines; Mice; MicroRNAs

2022
Osmolyte effect on enzymatic stability and reaction equilibrium of formate dehydrogenase.
    Physical chemistry chemical physics : PCCP, 2022, Nov-23, Volume: 24, Issue:45

    Topics: Betaine; Formate Dehydrogenases; Methylamines; Thermodynamics

2022
Trimethylamine N-oxide aggravated cognitive impairment from APP/PS1 mice and protective roles of voluntary exercise.
    Neurochemistry international, 2023, Volume: 162

    Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Betaine; Brain-Derived Neurotrophic Factor; Cathepsin B; Choline; Cognitive Dysfunction; Exercise; Mice; Motor Activity; Occludin

2023
The association between plasma choline, growth and neurodevelopment among Malawian children aged 6-15 months enroled in an egg intervention trial.
    Maternal & child nutrition, 2023, Volume: 19, Issue:2

    Topics: Betaine; Child; Choline; Cross-Sectional Studies; Humans; Infant; Methylamines

2023
Trimethylamine N-Oxide and White Matter Hyperintensity Volume Among Patients With Acute Ischemic Stroke.
    JAMA network open, 2023, 08-01, Volume: 6, Issue:8

    Topics: Aged; Betaine; Carnitine; Cerebral Small Vessel Diseases; Choline; Cross-Sectional Studies; Female; Humans; Ischemic Stroke; Male; Stroke; Stroke, Lacunar; White Matter

2023