betaine and s-adenosylmethionine

betaine has been researched along with s-adenosylmethionine in 86 studies

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-19907 (8.14)18.7374
1990's6 (6.98)18.2507
2000's30 (34.88)29.6817
2010's34 (39.53)24.3611
2020's9 (10.47)2.80

Authors

AuthorsStudies
Inoue, F; Kinugasa, A; Kizaki, Z; Kodo, N; Nakajima, H; Okochi, M; Sawada, T; Terada, N1
Debreceni, B; Farkas, V; Fischer, GM; Laszlo, A; Nemeti, B; Sandor, A; Schaffer, Z; Somogyi, C1
Dickenmann, M; Krähenbühl, S; Steiger, J; Vernez, L; Wenk, M1
Barshop, BA; Gangoiti, JA; Siuzdak, G; Wikoff, WR1
Mayatepek, E; Primassin, S; Spiekerkoetter, U; Ter Veld, F1
Cirule, H; Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Vilskersts, R; Volska, K1
Hoppel, CL; Ingalls, ST; Kerner, J; Minkler, PE; Stoll, MS2
Berge, RK; Bjørndal, B; Bohov, P; Bruheim, I; Nordrehaug, JE; Ramsvik, MS; Rostrup, E; Svardal, A1
Hollak, CE; Houten, SM; Houtkooper, RH; Schooneman, MG; Soeters, MR; Vaz, FM; Wanders, RJ1
Cirule, H; Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makrecka-Kuka, M; Sevostjanovs, E1
Gadgil, MD; Herrington, DM; Kanaya, AM; Kandula, NR; Lewis, MR; Sands, C1
Finkelstein, JD; Martin, JJ1
Chanarin, I; Deacon, R; Lumb, M; Perry, J1
Finkelstein, JD; Harris, BJ; Martin, JJ1
Badakhsh, S; Barak, AJ; Beckenhauer, HC; Tuma, DJ2
Thompson, W; Wong, ER1
Demain, AL; White, RF1
Benevenga, NJ2
Eguchi, T; Harada, Y; Kawamura, I; Kishi, T; Narisawa, K; Rosenblatt, DS; Sakura, N; Ueda, K1
Barak, AJ; Beckenhauer, HC; Junnila, M; Tuma, DJ1
Cooney, CA; Kodell, RL; Moore, SR; Wolff, GL1
Kim, SK; Kim, SY; Kim, YC1
McCarty, MF1
Kettunen, H; Peuranen, S; Remus, JC; Saarinen, MT; Tiihonen, K1
Gamsky, EA; Hicks, SM; Lehman-McKeeman, LD; Mar, MH; Vassallo, JD; Zeisel, SH1
Bose, N; Greenspan, P; Momany, C1
Choi, KH; Kim, SK; Kim, YC1
Barak, AJ; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Tuma, DJ1
Ashihara, H; Baba, S; Suzuki, M; Yasumoto, E1
Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA1
Barak, AJ; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Rogers, DD; Siford, GL; Sorrell, MF; Tuma, DJ1
Jung, YS; Kim, SK; Kim, YC1
Kim, SK; Kim, YC1
Al-Osaimi, AM; Argo, CK; Caldwell, SH; Chang, CY1
Christen, V; Duong, FH; Filipowicz, M; Heim, MH1
Boynton, A; Gregory, JF; James, SJ; Neuhouser, ML; Nijhout, HF; Reed, MC; Shane, B; Ulrich, CM1
Baldwin, CR; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Sorrell, MF; Tuma, DJ1
Allen, RH; Brosnan, JT; Brosnan, ME; Jacobs, RL; Mudd, SH; Stabler, SP; Vance, DE; Wagner, C1
Barve, S; Cave, M; Deaciuc, I; Joshi-Barve, S; McClain, C; Mendez, C; Song, Z1
Baldwin, CR; Kharbanda, KK; Mailliard, ME; Sorrell, MF; Tuma, DJ1
Allen, RH; Chwatko, G; Hendrickson, C; Jakubowski, H; Morton, DH; Mudd, SH; Niculescu, MD; Puffenberger, EG; Robinson, DL; Stabler, SP; Strauss, KA; Wagner, C1
Abdelmalek, MF; Barve, S; Benevenga, NJ; Halsted, CH; Kaplowitz, N; Kharbanda, KK; Liu, QY; Lu, SC; McClain, CJ; Purohit, V; Swanson, C; Zakhari, S1
Chan, C; Ji, C; Kaplowitz, N; Kuhlenkamp, J; Shinohara, M1
Castro, CC; Garrow, TA; Koutmos, M; Szegedi, SS1
Bardag-Gorce, F; French, BA; French, SW; Li, J; Lu, SC; Nguyen, SK; Oliva, J1
Kharbanda, KK2
Chambers, ST; Elmslie, JL; Fink, JN; George, PM; Lever, M; Richards, AM; Scott, RS; Slow, S1
Bleyle, L; Bradford, BU; Craig, CP; Koop, DR; Melnyk, S; O'Connell, TM; Pogribny, IP; Powell, CL; Rusyn, I; Threadgill, DW; Tsuchiya, M; Uehara, T1
Garrow, TA; Gupta, S; Jiracek, J; Kruger, WD; Li, L; Rozen, R; Schalinske, KL; Strakova, J; Williams, KT1
Bernsmeier, C; Duong, FH; Filipowicz, M; Heim, MH; Terracciano, L1
Aritsuka, T; Fukushima, M; Han, KH; Ishii, H; Kawakami, S; Nakamura, Y; Ohba, K; Okada, T; Sekikawa, M; Shimada, K; Uchino, H1
Buslon, VS; French, SW; Oliva, J; Zhong, J1
Bardag-Gorce, F; Barve, S; Kharbanda, KK; Molina, PE; Osna, NA1
Baltz, JM; Fortier, AL; Garrow, TA; Kooistra, M; Lee, MB; Lever, M; Slow, S; Trasler, JM; Zhang, B1
Geisel, J; Gortner, L; Hartmuth, K; Herrmann, W; Nijhout, HF; Obeid, R; Reed, MC; Rohrer, TR1
Barto, R; Blom, HJ; Imbard, A; Jakobs, C; Kok, RM; Smith, DE; Smulders, YM1
Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q1
Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH1
Barto, R; Benoist, JF; Blom, HJ; Czerkiewicz, I; Imbard, A; Muller, F; Rigal, O; Schlemmer, D1
Obeid, R1
Dayal, S; French, SW; Geng, Y; Halsted, CH; Hodzic, E; Kharbanda, KK; LaSalle, JM; Medici, V; Peerson, J; Schroeder, DI; Shibata, NM; Tillman, B; Tsukamoto, H; Woods, R1
Doperé, I; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Vansant, G1
Blankenfeldt, W; Misson, L; Seebeck, FP; Vit, A1
Brosnan, JT; Brosnan, ME; da Silva, RP; Deminice, R; Jacobs, RL; Kelly, KB; Lamarre, SG1
Kim, SK; Kim, YM; Kwak, HC; Oh, SJ1
Anilkumar, N; Brandes, RP; Brewer, AC; Burr, S; Caldwell, A; Dew, T; Dong, X; Halket, J; Hughes, RD; Martin, D; Mistry, RK; Murray, TV; Quaglia, A; Sawyer, GJ; Schröder, K; Shah, AM; Sherwood, R1
Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y1
Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL1
Bertics, SJ; Luchini, ND; White, HM; Zhang, Q1
Zeisel, S1
Chmurzynska, A; Malinowska, AM; Mlodzik, MA; Nowacka-Woszuk, J; Radziejewska, A; Szwengiel, A1
White, HM; Zhang, Q1
Arima, H; Fujii, T; Izu, H; Yamashita, S1
Ali, MA; Bakir, MB; Kamel, MA; Khalifa, EA; Refaat, R; Salama, MA1
Elango, R1
Chen, S; Fang, AP; He, TT; Hou, MJ; Long, JA; Lu, XT; Luo, Y; Tan, XY; Tang, ZH; Yishake, D; Zhong, RH; Zhu, HL1
Rosas-Rodríguez, JA; Valenzuela-Soto, EM1
Baylin, A; Burant, CF; Dolinoy, DC; Domino, SE; Goodrich, JM; LaBarre, JL; McCabe, CF; Padmanabhan, V; Treadwell, MC1
Calvisi, DF; Feo, CF; Feo, F; Pascale, RM; Simile, MM1
Lin, B; Liu, Q; Tao, Y1
Alberti, C; Benoist, JF; de Baulny, HO; Feillet, F; Garcia-Segarra, N; Guilmin-Crépon, S; Haignere, J; Imbard, A; Kaguelidou, F; Kuster, A; Magréault, S; Perronneau, I; Schiff, M; Schlemmer, D; Toumazi, A1
Fukuoka, H; Horiguchi, S; Kagawa, Y; Kawabata, T; Kubo, Y; Nishikawa, M; Shoji, K; Tajima, A1

Reviews

12 review(s) available for betaine and s-adenosylmethionine

ArticleYear
Evidence for alternative pathways of methionine catabolism.
    Advances in nutritional research, 1984, Volume: 6

    Topics: Animals; Betaine; Carbon Dioxide; Choline; Decarboxylation; Diet; Homocystinuria; Humans; Liver; Methionine; Models, Biological; Oxidation-Reduction; Propionates; S-Adenosylmethionine; Sarcosine; Transaminases

1984
Therapy of NAFLD: antioxidants and cytoprotective agents.
    Journal of clinical gastroenterology, 2006, Volume: 40 Suppl 1

    Topics: Acetylcysteine; Antioxidants; Betaine; Cholagogues and Choleretics; Disease Progression; Fatty Liver; Humans; Lipid Peroxidation; S-Adenosylmethionine; Ursodeoxycholic Acid; Vitamin E

2006
Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition.
    The Journal of nutritional biochemistry, 2007, Volume: 18, Issue:3

    Topics: Betaine; Cytokines; Dietary Supplements; Environmental Exposure; Fatty Liver; Female; Humans; Insulin Resistance; Life Style; Liver; Liver Cirrhosis; Metabolic Syndrome; Methionine; Middle Aged; Mitochondrial Diseases; Oxidative Stress; S-Adenosylmethionine; United States; Vitamin E; Xenobiotics; Zinc

2007
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:1

    Topics: Animals; Betaine; Disease Models, Animal; Folic Acid; Humans; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine

2007
Alcoholic liver disease and methionine metabolism.
    Seminars in liver disease, 2009, Volume: 29, Issue:2

    Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine

2009
Impact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseases.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:1

    Topics: Animals; Antigen Presentation; Betaine; Ethanol; Hepatitis C; Humans; Interferons; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; Methyltransferases; Proteasome Endopeptidase Complex; S-Adenosylmethionine; Tumor Necrosis Factor-alpha

2013
Methionine metabolic pathway in alcoholic liver injury.
    Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:1

    Topics: Aminobutyrates; Betaine; Biomarkers; Cystathionine; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Metabolic Networks and Pathways; Methionine; S-Adenosylmethionine

2013
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
    Nutrients, 2013, Sep-09, Volume: 5, Issue:9

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine

2013
Choline, Other Methyl-Donors and Epigenetics.
    Nutrients, 2017, Apr-29, Volume: 9, Issue:5

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cyclin-Dependent Kinase Inhibitor Proteins; Diet; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histones; Humans; Liver Neoplasms; Meta-Analysis as Topic; Mice; Models, Animal; Phenotype; S-Adenosylhomocysteine; S-Adenosylmethionine

2017
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur

2020
The glycine betaine role in neurodegenerative, cardiovascular, hepatic, and renal diseases: Insights into disease and dysfunction networks.
    Life sciences, 2021, Nov-15, Volume: 285

    Topics: Betaine; Cardiovascular Diseases; Cell Size; Humans; Hyperhomocysteinemia; Kidney Diseases; Liver Diseases; Neurodegenerative Diseases; Osmolar Concentration; S-Adenosylmethionine

2021
S-Adenosylmethionine: From the Discovery of Its Inhibition of Tumorigenesis to Its Use as a Therapeutic Agent.
    Cells, 2022, 01-25, Volume: 11, Issue:3

    Topics: Animals; Antiviral Agents; Betaine; Carcinogenesis; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Colorectal Neoplasms; Humans; Liver Neoplasms; Male; Methionine Adenosyltransferase; Non-alcoholic Fatty Liver Disease; Rats; Ribavirin; S-Adenosylmethionine

2022

Trials

4 trial(s) available for betaine and s-adenosylmethionine

ArticleYear
Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study.
    Lipids in health and disease, 2015, Dec-15, Volume: 14

    Topics: Adolescent; Adult; Animals; Atherosclerosis; Betaine; Carnitine; Choline; Chylomicrons; Cytokines; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Eicosapentaenoic Acid; Erythrocytes; Euphausiacea; Fatty Acids, Unsaturated; Female; Humans; Lipoproteins, VLDL; Male; Methylamines; Particle Size; Pilot Projects; Triglycerides

2015
Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine.
    Cardiovascular drugs and therapy, 2009, Volume: 23, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Betaine; Clofibric Acid; Cohort Studies; Diabetes Complications; Female; Homocysteine; Humans; Hypolipidemic Agents; Lipids; Male; S-Adenosylmethionine; Stroke

2009
S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse.
    PloS one, 2010, Nov-08, Volume: 5, Issue:11

    Topics: Adult; Antiviral Agents; Arthralgia; Betaine; Diarrhea; Drug Therapy, Combination; Fatigue; Female; Gastrointestinal Agents; Headache; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Pilot Projects; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Ribavirin; S-Adenosylmethionine; Time Factors; Treatment Outcome

2010
Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial.
    Orphanet journal of rare diseases, 2022, 11-14, Volume: 17, Issue:1

    Topics: Betaine; Child; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Humans; Methionine; Prospective Studies; S-Adenosylmethionine; Vitamin B 12 Deficiency

2022

Other Studies

70 other study(ies) available for betaine and s-adenosylmethionine

ArticleYear
Effect of sports activity on carnitine metabolism. Measurement of free carnitine, gamma-butyrobetaine and acylcarnitines by tandem mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Aug-06, Volume: 731, Issue:1

    Topics: Betaine; Carnitine; Exercise; Humans; Mass Spectrometry

1999
Metabolism of carnitine in phenylacetic acid-treated rats and in patients with phenylketonuria.
    Biochimica et biophysica acta, 2000, Jun-15, Volume: 1501, Issue:2-3

    Topics: Adult; Animals; Betaine; Carnitine; Female; Glutamic Acid; Homogentisic Acid; Humans; Ketoglutaric Acids; Liver; Male; Mass Spectrometry; Phenylacetates; Phenylketonurias; Phenylpyruvic Acids; Rats; Rats, Wistar

2000
Effect of L-carnitine on the kinetics of carnitine, acylcarnitines and butyrobetaine in long-term haemodialysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:2

    Topics: Adult; Aged; Betaine; Carnitine; Female; Humans; Male; Middle Aged; Renal Dialysis; Time Factors

2006
Metabolomics identifies perturbations in human disorders of propionate metabolism.
    Clinical chemistry, 2007, Volume: 53, Issue:12

    Topics: Acetylcarnitine; Adult; Amino Acid Metabolism, Inborn Errors; Betaine; Biomarkers; Carnitine; Child; Chromatography, High Pressure Liquid; Humans; Methylmalonic Acid; Plasma; Propionates; Spectrometry, Mass, Electrospray Ionization

2007
Carnitine supplementation induces acylcarnitine production in tissues of very long-chain acyl-CoA dehydrogenase-deficient mice, without replenishing low free carnitine.
    Pediatric research, 2008, Volume: 63, Issue:6

    Topics: Acyl-CoA Dehydrogenase, Long-Chain; Animals; Betaine; Carnitine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dietary Supplements; Humans; Lipid Metabolism, Inborn Errors; Liver; Mice; Mice, Knockout; Muscle, Skeletal; Palmitoyl Coenzyme A; Palmitoylcarnitine; Physical Exertion; Time Factors

2008
Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis.
    Vascular pharmacology, 2015, Volume: 72

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Betaine; Carnitine; Disease Progression; Female; Male; Mice

2015
Validated method for the quantification of free and total carnitine, butyrobetaine, and acylcarnitines in biological samples.
    Analytical chemistry, 2015, Sep-01, Volume: 87, Issue:17

    Topics: Animals; Betaine; Carnitine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Humans; Mesylates; Muscle, Skeletal; Rats; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Trimethylsilyl Compounds

2015
Quantitative acylcarnitine determination by UHPLC-MS/MS--Going beyond tandem MS acylcarnitine "profiles".
    Molecular genetics and metabolism, 2015, Volume: 116, Issue:4

    Topics: Acetyl-CoA C-Acyltransferase; Acyl-CoA Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Betaine; Carbon-Carbon Ligases; Carnitine; Chromatography, High Pressure Liquid; Female; Humans; Infant, Newborn; Isomerism; Lipid Metabolism, Inborn Errors; Male; Neonatal Screening; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Urea Cycle Disorders, Inborn

2015
The impact of altered carnitine availability on acylcarnitine metabolism, energy expenditure and glucose tolerance in diet-induced obese mice.
    Biochimica et biophysica acta, 2016, Volume: 1862, Issue:8

    Topics: Animals; Betaine; Carnitine; Dietary Fats; Energy Metabolism; Glucose Intolerance; Insulin Resistance; Liver; Mice; Mice, Obese; Muscle, Skeletal; Obesity

2016
Decrease in Long-Chain Acylcarnitine Tissue Content Determines the Duration of and Correlates with the Cardioprotective Effect of Methyl-GBB.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 121, Issue:2

    Topics: Animals; Betaine; Biotransformation; Cardiotonic Agents; Carnitine; Down-Regulation; gamma-Aminobutyric Acid; Half-Life; Heart; Male; Membrane Transport Modulators; Molecular Weight; Myocardial Infarction; Myocardium; Perfusion; Quaternary Ammonium Compounds; Random Allocation; Rats, Wistar; Solute Carrier Family 22 Member 5; Time Factors; Tissue Distribution

2017
Circulating metabolites and lipids are associated with glycaemic measures in South Asians.
    Diabetic medicine : a journal of the British Diabetic Association, 2021, Volume: 38, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Asia, Western; Betaine; Blood Glucose; Carnitine; Chromatography, Liquid; Cohort Studies; Diabetes Mellitus; Diglycerides; Female; Glycated Hemoglobin; Humans; Linear Models; Lipidomics; Logistic Models; Male; Mass Spectrometry; Metabolomics; Middle Aged; Proline; Sphingomyelins; Triglycerides; United States

2021
Methionine metabolism in mammals. Adaptation to methionine excess.
    The Journal of biological chemistry, 1986, Feb-05, Volume: 261, Issue:4

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Glutathione; Liver; Male; Methionine; Methionine Adenosyltransferase; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine

1986
In vivo oxidation of the methyl group of hepatic 5-methyltetrahydrofolate.
    Journal of clinical pathology, 1988, Volume: 41, Issue:11

    Topics: Adenosine; Animals; Betaine; Carbon Dioxide; Deoxyadenosines; Formyltetrahydrofolates; Glycine; Liver; Male; Methionine; Oxidation-Reduction; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Serine; Tetrahydrofolates; Thionucleosides; Time Factors

1988
Methionine metabolism in mammals. The methionine-sparing effect of cystine.
    The Journal of biological chemistry, 1988, Aug-25, Volume: 263, Issue:24

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine; Cystathionine beta-Synthase; Cystine; Diet; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine

1988
Effects of prolonged ethanol feeding on methionine metabolism in rat liver.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1987, Volume: 65, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alcoholism; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Kinetics; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine

1987
Choline oxidation and labile methyl groups in normal and choline-deficient rat liver.
    Biochimica et biophysica acta, 1972, Feb-21, Volume: 260, Issue:2

    Topics: Acetates; Alcohol Oxidoreductases; Aldehydes; Animals; Autoradiography; Betaine; Carbon Isotopes; Choline; Choline Deficiency; Chromatography; Fatty Acids, Nonesterified; Kinetics; Liver; Male; Methionine; Methylation; Mitochondria, Liver; NAD; Oxidoreductases; Phosphatidylcholines; Rats; S-Adenosylmethionine; Serotonin; Subcellular Fractions; Triglycerides; Tritium

1972
Catabolism of betaine and its relationship to cobalamin overproduction.
    Biochimica et biophysica acta, 1971, Apr-20, Volume: 237, Issue:1

    Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12

1971
Effect of betaine on S-adenosylmethionine levels in the cerebrospinal fluid in a patient with methylenetetrahydrofolate reductase deficiency and peripheral neuropathy.
    Journal of inherited metabolic disease, 1994, Volume: 17, Issue:5

    Topics: Adolescent; Betaine; Female; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Peripheral Nervous System Diseases; S-Adenosylmethionine

1994
Dietary betaine promotes generation of hepatic S-adenosylmethionine and protects the liver from ethanol-induced fatty infiltration.
    Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:3

    Topics: Animals; Betaine; Fatty Liver, Alcoholic; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Triglycerides

1993
The effect of betaine in reversing alcoholic steatosis.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:6

    Topics: Animals; Betaine; Fatty Liver, Alcoholic; Gastrointestinal Agents; Lipotropic Agents; Liver; Male; Rats; Rats, Wistar; S-Adenosylmethionine

1997
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:11

    Topics: 5-Methylcytosine; Agouti Signaling Protein; Animals; Betaine; Choline; Cytosine; Dietary Supplements; Female; Folic Acid; Gene Expression Regulation; Genomic Imprinting; Hair Color; Intercellular Signaling Peptides and Proteins; Male; Methionine; Mice; Mice, Inbred Strains; Pregnancy; Proteins; S-Adenosylmethionine; Vitamin B 12; Zinc

1998
Effect of betaine administration on metabolism of hepatic glutathione in rats.
    Archives of pharmacal research, 1998, Volume: 21, Issue:6

    Topics: Animals; Betaine; Cysteine; Female; Glutathione; Injections, Intraperitoneal; Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine

1998
Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy.
    Medical hypotheses, 2000, Volume: 55, Issue:3

    Topics: Animals; Betaine; Homocysteine; Hyperlipidemias; Liver; Niacin; Rats; S-Adenosylmethionine

2000
Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2001, Volume: 130, Issue:4

    Topics: Animals; Betaine; Chickens; Chromatography, High Pressure Liquid; Coccidia; Coccidiosis; Epithelium; Female; Gastrointestinal Agents; Homocysteine; Intestines; Jejunum; Liver; Male; Models, Biological; S-Adenosylmethionine

2001
Diethanolamine induces hepatic choline deficiency in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 67, Issue:1

    Topics: Administration, Cutaneous; Animals; Betaine; Carcinogens; Choline Deficiency; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Ethanolamines; Glycerylphosphorylcholine; Liver; Male; Mice; Mice, Inbred C57BL; No-Observed-Adverse-Effect Level; Phosphatidylcholines; Phosphorylcholine; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity

2002
Expression of recombinant human betaine: homocysteine S-methyltransferase for x-ray crystallographic studies and further characterization of interaction with S-adenosylmethionine.
    Protein expression and purification, 2002, Volume: 25, Issue:1

    Topics: Amino Acids; Animals; Base Sequence; Betaine; Betaine-Homocysteine S-Methyltransferase; Calorimetry; Cloning, Molecular; Crystallography, X-Ray; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Homocysteine S-Methyltransferase; Humans; Liver; Methyltransferases; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; S-Adenosylmethionine

2002
Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice.
    Biochemical pharmacology, 2003, May-01, Volume: 65, Issue:9

    Topics: Alkynes; Amino Acids; Animals; Betaine; Biological Transport; Cystathionine; Cystathionine gamma-Lyase; Cysteine Dioxygenase; Dioxygenases; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Glycine; Liver; Methionine; Mice; Mice, Inbred ICR; Oxygenases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Taurine

2003
Betaine lowers elevated s-adenosylhomocysteine levels in hepatocytes from ethanol-fed rats.
    The Journal of nutrition, 2003, Volume: 133, Issue:9

    Topics: Administration, Oral; Animals; Betaine; Ethanol; Hepatocytes; Male; Methionine; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine

2003
Effect of salt stress on the metabolism of ethanolamine and choline in leaves of the betaine-producing mangrove species Avicennia marina.
    Phytochemistry, 2003, Volume: 64, Issue:5

    Topics: Adaptation, Physiological; Adenosine Kinase; Avicennia; Betaine; Carbon Dioxide; Carbon Radioisotopes; Choline; Ethanolamines; N-Glycosyl Hydrolases; Organophosphorus Compounds; Plant Leaves; S-Adenosylmethionine; Sodium Chloride

2003
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:6

    Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12

2004
A comparison of the effects of betaine and S-adenosylmethionine on ethanol-induced changes in methionine metabolism and steatosis in rat hepatocytes.
    The Journal of nutrition, 2005, Volume: 135, Issue:3

    Topics: Animals; Betaine; Disease Models, Animal; Ethanol; Fatty Liver; Hepatocytes; Male; Methionine; Methyltransferases; Microsomes, Liver; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylmethionine

2005
Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by alpha-naphthylisothiocyanate.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2005, Volume: 43, Issue:5

    Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Amino Acids, Sulfur; Analysis of Variance; Animals; Aspartate Aminotransferases; Betaine; Bilirubin; Cholestasis; Cysteine; Dietary Supplements; Glutathione; Kinetics; Liver; Male; Mice; Mice, Inbred ICR; S-Adenosylhomocysteine; S-Adenosylmethionine

2005
Effects of betaine supplementation on hepatic metabolism of sulfur-containing amino acids in mice.
    Journal of hepatology, 2005, Volume: 42, Issue:6

    Topics: Amino Acids, Sulfur; Animals; Betaine; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; Glutathione; Kidney; Lipotropic Agents; Liver; Male; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred ICR; S-Adenosylmethionine; Solvents; Taurine

2005
S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:4

    Topics: Adenosine; Antiviral Agents; Betaine; Cell Line; DNA; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver; Methylation; Phosphoprotein Phosphatases; Protein Phosphatase 2C; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Signal Transduction; STAT1 Transcription Factor; Virus Replication

2006
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
    The Journal of nutrition, 2006, Volume: 136, Issue:10

    Topics: Betaine; Carbon; DNA Methylation; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Kinetics; Mathematics; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Molecular Biology; Nutritional Physiological Phenomena; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polymorphism, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency

2006
Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway.
    Journal of hepatology, 2007, Volume: 46, Issue:2

    Topics: Animals; Betaine; Diet; Ethanol; Fatty Liver, Alcoholic; Lipotropic Agents; Liver; Male; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides

2007
Methyl balance and transmethylation fluxes in humans.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:1

    Topics: Animals; Betaine; Creatine; Diet; Guanidinoacetate N-Methyltransferase; Humans; Kinetics; Liver; Methylation; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine

2007
Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: effects on protein-L-isoaspartyl methyltransferase activity.
    Journal of hepatology, 2007, Volume: 46, Issue:6

    Topics: Alcohols; Animals; Betaine; Catalysis; Diet; Ethanol; Liver; Male; Microsomes; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Subcellular Fractions

2007
Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency.
    Molecular genetics and metabolism, 2007, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Betaine; Brain; Brain Diseases; Child; Child, Preschool; Humans; Infant, Newborn; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Methyltransferases; Mutation, Missense; Neonatal Screening; S-Adenosylmethionine

2007
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:4

    Topics: Betaine; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Neural Tube Defects; Nutritional Physiological Phenomena; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex

2007
Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:5

    Topics: Animals; Apolipoproteins B; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Fatty Liver; Gene Transfer Techniques; Hepatocytes; Homocysteine; Humans; Lipid Metabolism; Liver Neoplasms; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Sterol Regulatory Element Binding Protein 1

2007
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
    The Journal of biological chemistry, 2008, Apr-04, Volume: 283, Issue:14

    Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Homocysteine; Homocysteine S-Methyltransferase; Humans; Metalloproteins; Methylation; Recombinant Proteins; S-Adenosylmethionine; Sarcosine; Substrate Specificity; Vitamin U; Zinc

2008
Betaine prevents Mallory-Denk body formation in drug-primed mice by epigenetic mechanisms.
    Experimental and molecular pathology, 2009, Volume: 86, Issue:2

    Topics: Animals; Betaine; Body Weight; Carboxylic Acids; Epigenesis, Genetic; Feeding Behavior; Gene Expression Regulation; Inclusion Bodies; Liver; Male; Mice; Oligonucleotide Array Sequence Analysis; Organ Size; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Thionucleosides

2009
Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 115, Issue:1

    Topics: Aldehyde Dehydrogenase; Animals; Betaine; Catalase; Central Nervous System Depressants; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dietary Fats; Dietary Supplements; Enzyme Induction; Ethanol; Glutathione; Liver; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C57BL; Peroxisomes; S-Adenosylmethionine

2010
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
    Nutrition research (New York, N.Y.), 2010, Volume: 30, Issue:7

    Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Diet; Enzyme Inhibitors; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine

2010
Amelioration of D-galactosamine-induced acute liver injury in rats by dietary supplementation with betaine derived from sugar beet molasses.
    Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:7

    Topics: Adenosylhomocysteinase; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Beta vulgaris; Betaine; Chemical and Drug Induced Liver Injury; Dietary Supplements; Galactosamine; Glutathione; Glutathione Peroxidase; Glutathione Transferase; L-Lactate Dehydrogenase; Liver; Male; Molasses; Rats; S-Adenosylmethionine

2011
The effect of SAMe and betaine on Hepa 1-6, C34 and E47 liver cell survival in vitro.
    Experimental and molecular pathology, 2012, Volume: 92, Issue:1

    Topics: Animals; Betaine; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Hepatocytes; Humans; Mice; S-Adenosylmethionine; Time Factors

2012
Betaine homocysteine methyltransferase is active in the mouse blastocyst and promotes inner cell mass development.
    The Journal of biological chemistry, 2012, Sep-21, Volume: 287, Issue:39

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Blastocyst; Cell Survival; Embryonic Development; Female; Gene Knockdown Techniques; Mice; Morula; RNA, Messenger; S-Adenosylmethionine

2012
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:10

    Topics: Adolescent; Adult; Betaine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Choline; Cystathionine; Cysteine; Down Syndrome; Female; Glutathione; Humans; Infant; Male; Methionine; Methylation; Models, Theoretical; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Young Adult

2012
Plasma choline and betaine correlate with serum folate, plasma S-adenosyl-methionine and S-adenosyl-homocysteine in healthy volunteers.
    Clinical chemistry and laboratory medicine, 2013, Mar-01, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Betaine; Choline; Chromatography, High Pressure Liquid; DNA Methylation; Female; Folic Acid; Gonadal Steroid Hormones; Humans; Linear Models; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Sex Factors; Tandem Mass Spectrometry; Young Adult

2013
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:4

    Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen

2013
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
    The American journal of clinical nutrition, 2013, Volume: 97, Issue:6

    Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult

2013
Methylation metabolites in amniotic fluid depend on gestational age.
    Prenatal diagnosis, 2013, Volume: 33, Issue:9

    Topics: Adult; Amniotic Fluid; Betaine; Choline; Female; Gestational Age; Humans; Methionine; Methylation; Methyltransferases; Pregnancy; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine

2013
Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse.
    Alcoholism, clinical and experimental research, 2014, Volume: 38, Issue:6

    Topics: Animals; Betaine; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Ethanol; Fatty Liver, Alcoholic; Gene Expression Regulation; Homocystinuria; Liver; Methionine; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; PPAR alpha; S-Adenosylhomocysteine; S-Adenosylmethionine

2014
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads.
    International journal of food sciences and nutrition, 2014, Volume: 65, Issue:6

    Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult

2014
Ergothioneine biosynthetic methyltransferase EgtD reveals the structural basis of aromatic amino acid betaine biosynthesis.
    Chembiochem : a European journal of chemical biology, 2015, Jan-02, Volume: 16, Issue:1

    Topics: Amino Acid Sequence; Ascomycota; Basidiomycota; Betaine; Catalytic Domain; Crystallography, X-Ray; Ergothioneine; Escherichia coli; Fungal Proteins; Gene Expression; Histidine; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutation; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan

2015
Betaine supplementation prevents fatty liver induced by a high-fat diet: effects on one-carbon metabolism.
    Amino acids, 2015, Volume: 47, Issue:4

    Topics: Acyltransferases; Animals; Betaine; Carbon; Diet, High-Fat; Dietary Supplements; Fatty Liver; Glycine N-Methyltransferase; Humans; Liver; Male; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides

2015
Sulfur amino acid metabolism in Zucker diabetic fatty rats.
    Biochemical pharmacology, 2015, Aug-01, Volume: 96, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Cysteine; Dipeptides; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Homocysteine; Liver; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine; Spermine; Taurine

2015
NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice.
    Free radical biology & medicine, 2015, Volume: 89

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Betaine; Blotting, Western; Cells, Cultured; Cysteine; Female; Glutathione; Hep G2 Cells; Homocysteine; Humans; Immunoenzyme Techniques; Liver; Liver Diseases; Methionine; Mice; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; S-Adenosylmethionine

2015
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:3

    Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors

2016
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
    The Journal of nutritional biochemistry, 2016, Volume: 35

    Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium

2016
The effect of increasing concentrations of dl-methionine and 2-hydroxy-4-(methylthio) butanoic acid on hepatic genes controlling methionine regeneration and gluconeogenesis.
    Journal of dairy science, 2016, Volume: 99, Issue:10

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Animals, Newborn; Betaine; Betaine-Homocysteine S-Methyltransferase; Carnitine O-Palmitoyltransferase; Cattle; Down-Regulation; Gluconeogenesis; Glucose-6-Phosphatase; Hepatocytes; Homocysteine; Liver; Methionine; Methionine Adenosyltransferase; Methylenetetrahydrofolate Reductase (NADPH2); Phosphoenolpyruvate Carboxykinase (GTP); S-Adenosylmethionine; Up-Regulation

2016
Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model.
    Biochimie, 2018, Volume: 152

    Topics: Animals; Betaine; Caloric Restriction; Carbon; Choline; DNA Methylation; Female; Gene Expression; Homocysteine; Hydrolases; Liver; Male; Methylamines; Models, Biological; Pregnancy; Pregnancy, Animal; Rats, Wistar; S-Adenosylmethionine

2018
Short communication: The effect of increasing concentrations of different methionine forms and 2-hydroxy-4-(methylthio)butanoic acid on genes controlling methionine metabolism in primary bovine neonatal hepatocytes.
    Journal of dairy science, 2019, Volume: 102, Issue:1

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Animals, Newborn; Betaine; Betaine-Homocysteine S-Methyltransferase; Butyric Acid; Cattle; Cells, Cultured; Female; Glycine N-Methyltransferase; Hepatocytes; Liver; Methionine; S-Adenosylmethionine

2019
Nutritional characterization of sake cake (sake-kasu) after heat-drying and freeze-drying.
    Bioscience, biotechnology, and biochemistry, 2019, Volume: 83, Issue:8

    Topics: Aspergillus oryzae; beta-Glucans; Betaine; Carbohydrate Metabolism; Choline; Food Handling; Freeze Drying; Fungal Proteins; Hot Temperature; Lipid Metabolism; Niacin; Nucleic Acids; Nutritive Value; Oryza; S-Adenosylmethionine; Saccharomyces cerevisiae; Vitamin B 6

2019
Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease.
    European journal of pharmacology, 2019, Mar-15, Volume: 847

    Topics: Animals; Betaine; Carbon; Choline; Diet, High-Fat; Dietary Supplements; DNA Methylation; Folic Acid; Glutathione; Homocysteine; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; S-Adenosylmethionine

2019
Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level.
    Molecular nutrition & food research, 2021, Volume: 65, Issue:15

    Topics: Aging; Animals; Betaine; Gene Expression Regulation; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Lysosomes; Male; Mechanistic Target of Rapamycin Complex 1; Methionine; Methyltransferases; Mice, Inbred C57BL; Muscle, Skeletal; Protein Biosynthesis; S-Adenosylmethionine; Signal Transduction

2021
Maternal and neonatal one-carbon metabolites and the epigenome-wide infant response.
    The Journal of nutritional biochemistry, 2022, Volume: 101

    Topics: Adult; Betaine; Carbon; Choline; Cohort Studies; DNA Methylation; Epigenome; Female; Fetal Blood; Histone Code; Humans; Infant, Newborn; Male; Maternal Nutritional Physiological Phenomena; Metabolomics; Methionine; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine

2022
Improved methylation in E. coli via an efficient methyl supply system driven by betaine.
    Metabolic engineering, 2022, Volume: 72

    Topics: Adenosine Triphosphate; Betaine; Escherichia coli; Homocysteine; Methylation; Methyltransferases; S-Adenosylmethionine

2022
Serum 5-Methyltetrahydrofolate Status Is Associated with One-Carbon Metabolism-Related Metabolite Concentrations and Enzyme Activity Indicators in Young Women.
    International journal of molecular sciences, 2023, Jul-01, Volume: 24, Issue:13

    Topics: Adolescent; Adult; Betaine; Carbon; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Pregnancy; S-Adenosylmethionine; Young Adult

2023