betaine has been researched along with s-adenosylhomocysteine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.03) | 18.7374 |
| 1990's | 1 (3.03) | 18.2507 |
| 2000's | 14 (42.42) | 29.6817 |
| 2010's | 16 (48.48) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Finkelstein, JD; Martin, JJ | 1 |
| Kim, SK; Kim, SY; Kim, YC | 1 |
| Gamsky, EA; Hicks, SM; Lehman-McKeeman, LD; Mar, MH; Vassallo, JD; Zeisel, SH | 1 |
| Choi, KH; Kim, SK; Kim, YC | 1 |
| Barak, AJ; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Tuma, DJ | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Jung, YS; Kim, SK; Kim, YC | 1 |
| Barak, AJ; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Rogers, DD; Siford, GL; Sorrell, MF; Tuma, DJ | 1 |
| Baldwin, CR; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Sorrell, MF; Tuma, DJ | 1 |
| Allen, RH; Brosnan, JT; Brosnan, ME; Jacobs, RL; Mudd, SH; Stabler, SP; Vance, DE; Wagner, C | 1 |
| Baldwin, CR; Kharbanda, KK; Mailliard, ME; Sorrell, MF; Tuma, DJ | 1 |
| Chan, C; Ji, C; Kaplowitz, N; Kuhlenkamp, J; Shinohara, M | 1 |
| Kharbanda, KK | 2 |
| Chen, YH; Hsieh, HM; Hu, ML; Lin, HC | 1 |
| Abdelmalek, MF; Angulo, P; Cave, M; Chen, T; Keach, J; Lindor, KD; Liu, C; McClain, CJ; Peter, J; Sanderson, SO; Soldevila-Pico, C | 1 |
| Garrow, TA; Gupta, S; Jiracek, J; Kruger, WD; Li, L; Rozen, R; Schalinske, KL; Strakova, J; Williams, KT | 1 |
| Geisel, J; Gortner, L; Hartmuth, K; Herrmann, W; Nijhout, HF; Obeid, R; Reed, MC; Rohrer, TR | 1 |
| Devaraj, S; Engelberg, JA; Halsted, CH; Havel, PJ; Jiang, JX; Kharbanda, KK; Kim, K; LaSalle, JM; Liu, S; Lönnerdal, B; Medici, V; Shibata, NM; Török, NJ; Woods, R | 1 |
| Barto, R; Blom, HJ; Imbard, A; Jakobs, C; Kok, RM; Smith, DE; Smulders, YM | 1 |
| Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
| Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH | 1 |
| Barto, R; Benoist, JF; Blom, HJ; Czerkiewicz, I; Imbard, A; Muller, F; Rigal, O; Schlemmer, D | 1 |
| Dayal, S; French, SW; Geng, Y; Halsted, CH; Hodzic, E; Kharbanda, KK; LaSalle, JM; Medici, V; Peerson, J; Schroeder, DI; Shibata, NM; Tillman, B; Tsukamoto, H; Woods, R | 1 |
| Doperé, I; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Vansant, G | 1 |
| Blankenfeldt, W; Misson, L; Seebeck, FP; Vit, A | 1 |
| Brosnan, JT; Brosnan, ME; da Silva, RP; Deminice, R; Jacobs, RL; Kelly, KB; Lamarre, SG | 1 |
| Kim, SK; Kim, YM; Kwak, HC; Oh, SJ | 1 |
| Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Deng, YC; Lai, MC; Lai, SJ | 1 |
| Zeisel, S | 1 |
| Baylin, A; Burant, CF; Dolinoy, DC; Domino, SE; Goodrich, JM; LaBarre, JL; McCabe, CF; Padmanabhan, V; Treadwell, MC | 1 |
3 review(s) available for betaine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Role of transmethylation reactions in alcoholic liver disease.
Topics: Betaine; Humans; Lipotropic Agents; Liver Diseases, Alcoholic; Methionine; Methyltransferases; S-Adenosylhomocysteine | 2007 |
Alcoholic liver disease and methionine metabolism.
Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
Choline, Other Methyl-Donors and Epigenetics.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cyclin-Dependent Kinase Inhibitor Proteins; Diet; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histones; Humans; Liver Neoplasms; Meta-Analysis as Topic; Mice; Models, Animal; Phenotype; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
1 trial(s) available for betaine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial.
Topics: Adipokines; Adult; Aged; Betaine; Cytokines; Double-Blind Method; Fatty Liver; Female; Humans; Male; Middle Aged; S-Adenosylhomocysteine | 2009 |
29 other study(ies) available for betaine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Methionine metabolism in mammals. Adaptation to methionine excess.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Glutathione; Liver; Male; Methionine; Methionine Adenosyltransferase; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine | 1986 |
Effect of betaine administration on metabolism of hepatic glutathione in rats.
Topics: Animals; Betaine; Cysteine; Female; Glutathione; Injections, Intraperitoneal; Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1998 |
Diethanolamine induces hepatic choline deficiency in mice.
Topics: Administration, Cutaneous; Animals; Betaine; Carcinogens; Choline Deficiency; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Ethanolamines; Glycerylphosphorylcholine; Liver; Male; Mice; Mice, Inbred C57BL; No-Observed-Adverse-Effect Level; Phosphatidylcholines; Phosphorylcholine; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity | 2002 |
Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice.
Topics: Alkynes; Amino Acids; Animals; Betaine; Biological Transport; Cystathionine; Cystathionine gamma-Lyase; Cysteine Dioxygenase; Dioxygenases; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Glycine; Liver; Methionine; Mice; Mice, Inbred ICR; Oxygenases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Taurine | 2003 |
Betaine lowers elevated s-adenosylhomocysteine levels in hepatocytes from ethanol-fed rats.
Topics: Administration, Oral; Animals; Betaine; Ethanol; Hepatocytes; Male; Methionine; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Amino Acids, Sulfur; Analysis of Variance; Animals; Aspartate Aminotransferases; Betaine; Bilirubin; Cholestasis; Cysteine; Dietary Supplements; Glutathione; Kinetics; Liver; Male; Mice; Mice, Inbred ICR; S-Adenosylhomocysteine; S-Adenosylmethionine | 2005 |
Role of elevated S-adenosylhomocysteine in rat hepatocyte apoptosis: protection by betaine.
Topics: Adenosine; Animals; Apoptosis; Betaine; Caspase 3; Caspases; Cells, Cultured; Cytoprotection; DNA Fragmentation; Ethanol; Hepatocytes; Male; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine | 2005 |
Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway.
Topics: Animals; Betaine; Diet; Ethanol; Fatty Liver, Alcoholic; Lipotropic Agents; Liver; Male; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2007 |
Methyl balance and transmethylation fluxes in humans.
Topics: Animals; Betaine; Creatine; Diet; Guanidinoacetate N-Methyltransferase; Humans; Kinetics; Liver; Methylation; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine | 2007 |
Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: effects on protein-L-isoaspartyl methyltransferase activity.
Topics: Alcohols; Animals; Betaine; Catalysis; Diet; Ethanol; Liver; Male; Microsomes; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Subcellular Fractions | 2007 |
Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.
Topics: Animals; Apolipoproteins B; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Fatty Liver; Gene Transfer Techniques; Hepatocytes; Homocysteine; Humans; Lipid Metabolism; Liver Neoplasms; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Sterol Regulatory Element Binding Protein 1 | 2007 |
S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Aspartic Acid Endopeptidases; Betaine; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Lipotropic Agents; Methylation; Mice; Microglia; Presenilin-1; Promoter Regions, Genetic; S-Adenosylhomocysteine; Time Factors | 2009 |
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Diet; Enzyme Inhibitors; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
Topics: Adolescent; Adult; Betaine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Choline; Cystathionine; Cysteine; Down Syndrome; Female; Glutathione; Humans; Infant; Male; Methionine; Methylation; Models, Theoretical; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Young Adult | 2012 |
Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease.
Topics: Adenosylhomocysteinase; Animals; Betaine; Copper; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Down-Regulation; Endoplasmic Reticulum Stress; Epigenesis, Genetic; Hepatolenticular Degeneration; Inflammation; Liver; Methionine; Mice; Mice, Inbred C3H; Penicillamine; S-Adenosylhomocysteine | 2013 |
Plasma choline and betaine correlate with serum folate, plasma S-adenosyl-methionine and S-adenosyl-homocysteine in healthy volunteers.
Topics: Adolescent; Adult; Betaine; Choline; Chromatography, High Pressure Liquid; DNA Methylation; Female; Folic Acid; Gonadal Steroid Hormones; Humans; Linear Models; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Sex Factors; Tandem Mass Spectrometry; Young Adult | 2013 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
Methylation metabolites in amniotic fluid depend on gestational age.
Topics: Adult; Amniotic Fluid; Betaine; Choline; Female; Gestational Age; Humans; Methionine; Methylation; Methyltransferases; Pregnancy; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine | 2013 |
Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse.
Topics: Animals; Betaine; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Ethanol; Fatty Liver, Alcoholic; Gene Expression Regulation; Homocystinuria; Liver; Methionine; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; PPAR alpha; S-Adenosylhomocysteine; S-Adenosylmethionine | 2014 |
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads.
Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult | 2014 |
Ergothioneine biosynthetic methyltransferase EgtD reveals the structural basis of aromatic amino acid betaine biosynthesis.
Topics: Amino Acid Sequence; Ascomycota; Basidiomycota; Betaine; Catalytic Domain; Crystallography, X-Ray; Ergothioneine; Escherichia coli; Fungal Proteins; Gene Expression; Histidine; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutation; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan | 2015 |
Betaine supplementation prevents fatty liver induced by a high-fat diet: effects on one-carbon metabolism.
Topics: Acyltransferases; Animals; Betaine; Carbon; Diet, High-Fat; Dietary Supplements; Fatty Liver; Glycine N-Methyltransferase; Humans; Liver; Male; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2015 |
Sulfur amino acid metabolism in Zucker diabetic fatty rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Cysteine; Dipeptides; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Homocysteine; Liver; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine; Spermine; Taurine | 2015 |
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors | 2016 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
Comparison of Enzymatic Traits between Native and Recombinant Glycine Sarcosine N-Methyltransferase from Methanohalophilus portucalensis FDF1T.
Topics: Archaeal Proteins; Betaine; Escherichia coli; Glycine; Glycine N-Methyltransferase; Kinetics; Methanosarcinaceae; Protein Processing, Post-Translational; S-Adenosylhomocysteine; Sarcosine | 2016 |
Maternal and neonatal one-carbon metabolites and the epigenome-wide infant response.
Topics: Adult; Betaine; Carbon; Choline; Cohort Studies; DNA Methylation; Epigenome; Female; Fetal Blood; Histone Code; Humans; Infant, Newborn; Male; Maternal Nutritional Physiological Phenomena; Metabolomics; Methionine; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine | 2022 |