betaine and pyridoxine

betaine has been researched along with pyridoxine in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (21.43)	18.7374
1990's	5 (17.86)	18.2507
2000's	9 (32.14)	29.6817
2010's	8 (28.57)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bernardini, I; Chen, S; Gahl, WA; Horvath, K; Kurtz, D	1
Dudman, NP; Tyrrell, PA; Wilcken, DE	1
Josephs, JA; Magazino, J; Parker, CM; Sprince, H	1
Fuller, HL; Keshavarz, K	1
Dudman, NP; Tyrrell, PA; Wilcken, B; Wilcken, DE	1
Benevenga, NJ; Berlow, S; Smolin, LA	1
Boers, GH	1
Cabello Tomás, ML; Dalmau Serra, J; García Gómez, AM; Montero Brens, C; Rodes Monegal, M; Vilaseca Busca, A	1
Bridge, C; Till, J; Walter, JH; White, FJ; Wraith, JE	1
Blom, HJ; Boers, GH; Cruysberg, JR; Kluijtmans, LA; Kraus, JP; Trijbels, FJ; van den Heuvel, LP	1
Berrettini, M; Burlina, A; Cella, G; Girolami, A; Motta, G; Sbarai, A; Strauss, W	1
Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Robson, RA	2
Boers, GH; Brenton, DP; Howard, PM; Lee, PJ; Naughten, ER; Walter, JH; Wilcken, B; Wilcken, DE; Yap, S	1
al-Essa, MA; Ozand, PT; Rashed, MS	1
Keeling, D; Leonard, J; Pike, M; Vorstman, E	1
Bonham, JR; Chakrapani, A; Johnson, TN; Matthews, A; Moat, SJ; Rostami-Hodjegan, A; Tucker, GT; Wraith, JE	1
Balcells, S; Cuartero, ML; Grinberg, D; Lambruschini, N; Martinez de Salinas, M; Pintó, X; Urreizti, R; Vilaseca, MA	1
Chakrapani, A; Gissen, P; McDonald, A; Pierre, G; Preece, M; Wright, J	1
Du, NS; Hu, JP; Rena, K; Yang, JH	1
Barski, R; Luvai, A; Narayanan, D; Sharma, R	1
Adam, S; Almeida, MF; Carbasius Weber, E; Champion, H; Chan, H; Daly, A; Dixon, M; Dokoupil, K; Egli, D; Evans, S; Eyskens, F; Faria, A; Ferguson, C; Hallam, P; Heddrich-Ellerbrok, M; Jacobs, J; Jankowski, C; Lachmann, R; Lilje, R; Link, R; Lowry, S; Luyten, K; MacDonald, A; Maritz, C; Martins, E; Meyer, U; Müller, E; Murphy, E; Robertson, LV; Rocha, JC; Saruggia, I; Schick, P; Stafford, J; Stoelen, L; Terry, A; Thom, R; van den Hurk, T; van Rijn, M; van Teefelen-Heithoff, A; Webster, D; White, FJ; Wildgoose, J; Zweers, H	1
Andria, G; Ben-Omran, TI; Blom, HJ; Chakrapani, AB; Chapman, KA; Crushell, E; de Almeida, IT; Henderson, MJ; Hochuli, M; Huemer, M; Janssen, MC; Kožich, V; Maillot, F; Mayne, PD; McNulty, J; Morris, AA; Morrison, TM; O'Sullivan, S; Ogier, H; Pavlíková, M; Santra, S; Terry, A; Yap, S	1
Dawson, C; Geberhiwot, T; Senthil, L; Woods, E	1

Reviews

3 review(s) available for betaine and pyridoxine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Hyperhomocysteinaemia: a newly recognized risk factor for vascular disease. The Netherlands journal of medicine, 1994, Volume: 45, Issue:1 Topics: Arteriosclerosis; Betaine; Coronary Disease; Folic Acid; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Methionine; Pyridoxine; Risk Factors; Vascular Diseases	1994
Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency. Journal of inherited metabolic disease, 2017, Volume: 40, Issue:1 Topics: Betaine; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Humans; Methionine; Pyridoxine	2017

Trials

3 trial(s) available for betaine and pyridoxine

Article	Year
The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. Journal of inherited metabolic disease, 1988, Volume: 11, Issue:3 Topics: Adolescent; Adult; Amino Acids; Betaine; Child; Female; Homocystine; Homocystinuria; Humans; Male; Methionine; Minerals; Pyridoxine; Spine; Tomography, X-Ray Computed	1988
Vascular outcome in patients with homocystinuria due to cystathionine beta-synthase deficiency treated chronically: a multicenter observational study. Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:12 Topics: Adolescent; Adult; Aged; Betaine; Cardiovascular Diseases; Child; Child, Preschool; Comorbidity; Drug Therapy, Combination; Folic Acid; Follow-Up Studies; Homocystinuria; Humans; Middle Aged; Pyridoxine; Risk Assessment	2001
Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure. Kidney international, 2002, Volume: 61, Issue:3 Topics: Aged; Betaine; Cross-Over Studies; Drug Therapy, Combination; Fasting; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipids; Male; Methionine; Middle Aged; Pyridoxine; Sarcosine	2002

Other Studies

22 other study(ies) available for betaine and pyridoxine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism: clinical and experimental, 1985, Volume: 34, Issue:12 Topics: Adolescent; Adult; Betaine; Child; Cystathionine beta-Synthase; Cysteine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Male; Methionine; Middle Aged; Pyridoxine; Serine	1985
Convulsant activity of homocysteine and other short-chain mercaptoacids: protection therefrom. Annals of the New York Academy of Sciences, 1969, Sep-30, Volume: 166, Issue:1 Topics: Animals; Betaine; Central Nervous System Stimulants; Cysteine; Glycine; Homocysteine; Male; Methionine; Phenobarbital; Pyridoxine; Rats; Serine	1969
Relationship of arginine and methionine in the nutrition of the chick and the significance of creatine biosynthesis in their interaction. The Journal of nutrition, 1971, Volume: 101, Issue:2 Topics: Aminobutyrates; Animal Feed; Animals; Arginine; Betaine; Chickens; Creatine; Diet; Drug Antagonism; Drug Synergism; Glycine; Lysine; Methionine; Muscles; Nutritional Physiological Phenomena; Pyridoxine	1971
Homocystinuria--the effects of betaine in the treatment of patients not responsive to pyridoxine. The New England journal of medicine, 1983, Aug-25, Volume: 309, Issue:8 Topics: Amino Acids; Amino Acids, Sulfur; Betaine; Cystathionine beta-Synthase; Cysteine; Female; Homocysteine; Homocystinuria; Humans; Male; Pyridoxine; Vitamin B 12	1983
The use of betaine for the treatment of homocystinuria. The Journal of pediatrics, 1981, Volume: 99, Issue:3 Topics: Administration, Oral; Adult; Betaine; Child; Female; Folic Acid; Homocystine; Homocystinuria; Humans; Male; Methionine; Pyridoxine	1981
[Homocystinuria: effectiveness of the treatment with pyridoxine, folic acid, and betaine]. Anales espanoles de pediatria, 1993, Volume: 39, Issue:1 Topics: Betaine; Child; Child, Preschool; Drug Evaluation; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Male; Pyridoxine	1993
Strategies for the treatment of cystathionine beta-synthase deficiency: the experience of the Willink Biochemical Genetics Unit over the past 30 years. European journal of pediatrics, 1998, Volume: 157 Suppl 2 Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Female; Folic Acid; Gastrointestinal Agents; Genetic Testing; Homocysteine; Homocystinuria; Humans; Infant; Infant, Newborn; Male; Pregnancy; Pregnancy Complications; Pyridoxine; Treatment Failure; Treatment Outcome	1998
The molecular basis of cystathionine beta-synthase deficiency in Dutch patients with homocystinuria: effect of CBS genotype on biochemical and clinical phenotype and on response to treatment. American journal of human genetics, 1999, Volume: 65, Issue:1 Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Cystathionine beta-Synthase; Female; Fibroblasts; Folic Acid; Genotype; Homocystinuria; Humans; Male; Middle Aged; Mutation; Netherlands; Phenotype; Pyridoxine	1999
Tissue factor pathway inhibitor levels in patients with homocystinuria. Thrombosis research, 2000, Jun-01, Volume: 98, Issue:5 Topics: Adult; Betaine; Biomarkers; Cystathionine beta-Synthase; Endothelium; Factor VII; Female; Fibrinolytic Agents; Heparin; Homocysteine; Homocystinuria; Homozygote; Humans; Lipoproteins; Male; Protein C; Pyridoxine; Serine Proteinase Inhibitors; Thrombomodulin; Thromboplastin; Vascular Diseases; Vitamin B 12	2000
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations. Kidney international, 2001, Volume: 59, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Betaine; Betaine-Homocysteine S-Methyltransferase; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methyltransferases; Middle Aged; Peritoneal Dialysis; Predictive Value of Tests; Pyridoxine; Renal Dialysis; Sarcosine; Uremia; Vitamin B 12; Zinc	2001
Classic homocystinuria: clinical, biochemical and radiological observations, and therapeutic outcome of 24 Saudi patients. Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 1999, Volume: 5, Issue:6 Topics: Betaine; Child; Child, Preschool; Combined Modality Therapy; Consanguinity; Drug Monitoring; Drug Therapy, Combination; Female; Folic Acid; Homocystinuria; Humans; Infant; Male; Methionine; Pedigree; Pyridoxine; Saudi Arabia; Treatment Outcome	1999
Sagittal sinus thrombosis in a teenager: homocystinuria associated with reversible antithrombin deficiency. Developmental medicine and child neurology, 2002, Volume: 44, Issue:7 Topics: Adolescent; Antithrombin III Deficiency; Betaine; Child; Drug Therapy, Combination; Heparin; Heparin, Low-Molecular-Weight; Homocystinuria; Humans; Male; Pyridoxine; Risk Factors; Sagittal Sinus Thrombosis	2002
An indirect response model of homocysteine suppression by betaine: optimising the dosage regimen of betaine in homocystinuria. British journal of clinical pharmacology, 2002, Volume: 54, Issue:2 Topics: Administration, Oral; Adolescent; Betaine; Child; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Female; Homocysteine; Homocystinuria; Humans; Male; Pyridoxine; Treatment Failure	2002
Two successful pregnancies in pyridoxine-nonresponsive homocystinuria. Journal of inherited metabolic disease, 2004, Volume: 27, Issue:6 Topics: Abortion, Spontaneous; Adult; Anticoagulants; Betaine; Diet, Protein-Restricted; Female; Gastrointestinal Agents; Homocystinuria; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Pyridoxine	2004
Successful treatment of pyridoxine-unresponsive homocystinuria with betaine in pregnancy. Journal of inherited metabolic disease, 2006, Volume: 29, Issue:5 Topics: Adult; Betaine; Female; Gastrointestinal Agents; Homocystinuria; Humans; Pregnancy; Pregnancy Complications; Pyridoxine	2006
[Studies on chemical constituents of cultivated Cistanche salsa]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:11 Topics: Betaine; Cistanche; Glucosides; Plants, Medicinal; Pyridoxine; Sitosterols	2008
Stroke in a young man. BMJ (Clinical research ed.), 2013, Jul-15, Volume: 347 Topics: Adult; Betaine; Cystathionine beta-Synthase; Diet, Protein-Restricted; Homocysteine; Homocystinuria; Humans; Lipotropic Agents; Male; Methionine; Platelet Aggregation Inhibitors; Pyridoxine; Stroke; Treatment Outcome; Vision Disorders; Vitamin B Complex	2013
Dietary practices in pyridoxine non-responsive homocystinuria: a European survey. Molecular genetics and metabolism, 2013, Volume: 110, Issue:4 Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Diet, Protein-Restricted; Europe; Female; Homocysteine; Homocystinuria; Humans; Infant; Male; Methionine; Pyridoxine; Surveys and Questionnaires; Treatment Outcome	2013
Cerebral venous thrombosis as the first presentation of classical homocystinuria in an adult patient. BMJ case reports, 2017, Jan-30, Volume: 2017 Topics: Adult; Betaine; Cerebral Angiography; Computed Tomography Angiography; Diagnostic Errors; Dysarthria; Encephalitis, Viral; Female; Headache; Homocystinuria; Humans; Lipotropic Agents; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Migraine Disorders; Paresis; Phlebography; Pulmonary Embolism; Pyridoxine; Sinus Thrombosis, Intracranial; Vitamin B Complex	2017