betaine has been researched along with homocysteine in 252 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (17.46) | 18.7374 |
| 1990's | 19 (7.54) | 18.2507 |
| 2000's | 90 (35.71) | 29.6817 |
| 2010's | 73 (28.97) | 24.3611 |
| 2020's | 26 (10.32) | 2.80 |
| Authors | Studies |
|---|---|
| Beaton, JM; Bradley, RJ; Smythies, JR | 1 |
| Balińska, M; Paszewski, A | 1 |
| Canfield, CJ; McCormick, GJ; Smith, CC | 1 |
| Freed, WJ; Gillin, JC; Wyatt, RJ | 1 |
| Labadie, P | 1 |
| Poirier, LA; Wilson, MJ | 1 |
| Dudman, NP; Lynch, J; Wang, JA; Wilcken, DE | 1 |
| Baker, DH; Czarnecki, GL | 1 |
| Vance, DE; Yao, ZM | 1 |
| Dudman, NP; Wilcken, DE; Wiley, VC | 1 |
| Dudman, NP; Tyrrell, PA; Wilcken, DE | 2 |
| Finkelstein, JD; Harris, BJ; Martin, JJ | 1 |
| Barak, AJ; Beckenhauer, HC; Tuma, DJ | 2 |
| Beaton, JM; Bradley, RJ; Bridgers, WF; McClain, LD; Pegram, GV; Smythies, JR | 1 |
| Nath, MC; Nath, N | 1 |
| Josephs, JA; Magazino, J; Parker, CM; Sprince, H | 1 |
| Finkelstein, JD; Harris, BJ; Kyle, WE | 2 |
| Halbach, G; Trost, W; Vogel, G | 1 |
| Birnbaum, J; Kaplan, L; White, RF | 1 |
| Howell, JN; Jaenicke, L; Sauer, H | 1 |
| Batra, KK; Buehring, KU; Stokstad, EL | 1 |
| Finkelstein, JD; Harris, BJ; Kyle, W | 1 |
| Josephs, JA; Parker, CM; Sprince, H | 1 |
| Chalmers, FT; Finkelstein, JD | 1 |
| Levy, H; Morrow, G; Mudd, SH | 1 |
| Shapshak, P | 1 |
| Demain, AL; White, RF | 1 |
| Pittoni, A; Rubaltelli, FF | 1 |
| Pittoni, A; Rubaltelli, FF; Sussi, PL | 1 |
| Khairallah, EA; Wolf, G | 1 |
| Shieh, HS | 1 |
| Freed, WJ; Hoffer, BJ; Wuerthele, SE; Yasuda, RP | 1 |
| Barak, AJ; Tuma, DJ | 1 |
| Metz, J; van der Westhuyzen, J | 1 |
| Dudman, NP; Tyrrell, PA; Wilcken, B; Wilcken, DE | 1 |
| Barak, AJ; Kemmy, RJ; Tuma, DJ | 1 |
| Finkelstein, JD; Martin, JJ | 1 |
| Balińska, M; Grzelakowska-Sztabert, B | 1 |
| Dudman, NP; Kuchel, PW; Lundberg, P; Wilcken, DE | 1 |
| Allen, RH; Lindenbaum, J; Stabler, SP | 1 |
| Allen, RH; Bostom, AG; Nadeau, MR; Selhub, J; Shemin, D; Shih, V; Stabler, SP | 1 |
| Boers, GH | 1 |
| Cabello Tomás, ML; Dalmau Serra, J; García Gómez, AM; Montero Brens, C; Rodes Monegal, M; Vilaseca Busca, A | 1 |
| Ganther, HE; Goeger, DE | 1 |
| Kang, SS | 1 |
| Dawson, PA; Dudman, NP; Gordon, RB; Guo, XW; Wilcken, DE | 1 |
| Baker, DH; Emmert, JL; Garrow, TA | 1 |
| Kjellman, B; Ronge, E | 1 |
| Engelbrecht, V; Huismann, J; Rassek, M; Wendel, U | 1 |
| Bowron, A; Leonard, J; Surtees, R | 1 |
| Donker, AJ; Jakobs, C; Janssen, MJ; Lambert, J; Stehouwer, CD; ter Wee, PM; van Guldener, C | 1 |
| Bridge, C; Till, J; Walter, JH; White, FJ; Wraith, JE | 1 |
| Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J | 1 |
| de Meer, K; Donker, AJ; Janssen, MJ; Stehouwer, CD; van Guldener, C | 1 |
| Mar, MH; Zeisel, SH | 1 |
| Berrettini, M; Burlina, A; Cella, G; Girolami, A; Motta, G; Sbarai, A; Strauss, W | 1 |
| Boers, GH; Levy, HL; Mudd, SH; Tangerman, A; Wilcken, B | 1 |
| Bassan, H; Fattal-Valevski, A; Gutman, A; Harel, S; Korman, SH; Lerman-Sagie, T | 1 |
| Brouwer, IA; Urgert, R; Verhoef, P | 1 |
| McCarty, MF | 1 |
| Chadwick, LH; McCandless, SE; Nadeau, JH; Schwartz, S; Silverman, GL; Westaway, D | 1 |
| Eilders, LL; Patel, BP; Sims, M; Waddell, TG | 1 |
| Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Robson, RA | 1 |
| Incharoensakdi, A; Waditee, R | 1 |
| Kettunen, H; Peuranen, S; Remus, JC; Saarinen, MT; Tiihonen, K | 1 |
| Mizoguchi, N; Ono, H; Sakamoto, A; Sakura, N | 1 |
| Barak, AJ; Beckenhauer, HC; Kharbanda, KK; Tuma, DJ | 1 |
| Desouza, C; Fonseca, V; Keebler, M; McNamara, DB | 1 |
| Nishimura, Y; Ono, H; Sakamoto, A; Sakura, N | 1 |
| Bonham, JR; Chakrapani, A; Johnson, TN; Matthews, A; Moat, SJ; Rostami-Hodjegan, A; Tucker, GT; Wraith, JE | 1 |
| Campillo, N; Garrido, F; Gasset, M; González, B; Pajares, MA; Sanz-Aparicio, J | 1 |
| Castro, C; Chen, Z; Garrow, T; Genest, J; Laryea, MD; Lussier-Cacan, S; Mar, MH; Rozen, R; Schwahn, BC; Wendel, U; Zeisel, SH | 1 |
| Katan, MB; Steenge, GR; Verhoef, P | 1 |
| Ji, C; Kaplowitz, N | 2 |
| Sakamoto, A; Sakura, N | 1 |
| Kacprzak, MM; Lewandowska, I; Matthews, RG; Paszewski, A | 1 |
| FIEDLER, E; GUELZOW, M | 1 |
| Boelsma, E; Olthof, MR; van Vliet, T; Verhoef, P | 1 |
| Bleie, Ø; Holm, PI; Lien, EA; Nordrehaug, JE; Nygård, O; Refsum, H; Ueland, PM | 1 |
| KENSLER, CJ; LANGEMANN, H | 1 |
| Chambers, ST; George, PM; Lee, MB; Lever, M; Slow, S | 1 |
| Castro, C; Collinsová, M; Evans, JC; Garrow, TA; Gratson, AA; Jiracek, J; Ludwig, ML | 1 |
| Castro, C; Garrow, TA; Leclerc, D; Lussier-Cacan, S; Mar, MH; Rozen, R; Schwahn, BC; Wendel, U; Zeisel, SH | 1 |
| Chen, Z; Garrow, T; James, SJ; Laryea, MD; Melnyk, S; Pogribny, I; Rozen, R; Schwahn, BC | 1 |
| Chambers, ST; George, PM; Lee, MB; Lever, M; McGregor, DO; Slow, S | 1 |
| Alfthan, G; Aro, A; Nissinen, K; Saarela, J; Tapani, K | 1 |
| Blom, HJ; den Heijer, M; Holm, PI; Keijzer, MB; Midttun, Ø; Ueland, PM; Vollset, SE | 1 |
| Chambers, ST; Dellow, WJ; George, PM; Lever, M; Scott, RS | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Nakata, R; Okawa, N; Shigematsu, N; Yagisawa, M | 1 |
| Fowler, B; Gutsche, S; Hennermann, JB; Horneff, G; Kozich, V; Mueller, P; Novotna, Z; Suormala, T; Vilarinho, L; Vilaseca, MA; Wilichowski, E; Zavadáková, P; Zeman, J | 1 |
| Olthof, MR; Verhoef, P | 1 |
| Boxer, AL; Finley, R; Goldman, J; Johnston, K; Kramer, JH; Miller, BL | 1 |
| Katan, MB; Olthof, MR; van Vliet, T; Verhoef, P; Zock, PL | 1 |
| Clarke, R; Holm, PI; Melse-Boonstra, A; Olthof, M; Ueland, PM; Verhoef, P | 1 |
| Fokkema, MR; Holm, PI; Muskiet, FA; Ueland, PM; van der Dijs, FP; Velzing-Aarts, FV | 1 |
| Fulton, AB; Hansen, RM; Marsden, DL; Tsina, EK | 1 |
| Holm, PI; Hustad, S; Ueland, PM | 1 |
| Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM | 1 |
| Alscher, DM; Benzinger, P | 1 |
| Brosnan, JT; Brosnan, ME; Hall, B; Ratnam, S; Wijekoon, EP; Zeisel, SH | 1 |
| Alfthan, G; Aro, A; Meririnne, E; Saarinen, M; Schwab, U; Törrönen, A; Uusitupa, M | 1 |
| Beers, KW; Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB | 1 |
| Heyrovský, M; Kohlíková, E; Navrátil, T; Pelclová, D; Petr, M; Pristoupil, TI; Pristoupilová, K; Senholdová, Z | 1 |
| Zeisel, SH | 2 |
| Lawson-Yuen, A; Levy, HL | 1 |
| Cho, E; Colditz, GA; Dougherty, L; Jacques, P; Selhub, J; Willett, WC; Zeisel, SH | 1 |
| Nakajima, K | 1 |
| Hasman, D; Innis, SM | 1 |
| Chan, C; Ji, C; Kaplowitz, N | 1 |
| Nakata, R; Shigematsuo, N; Yagisawa, M | 1 |
| Boynton, A; Gregory, JF; James, SJ; Neuhouser, ML; Nijhout, HF; Reed, MC; Shane, B; Ulrich, CM | 1 |
| Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB | 1 |
| Pajares, MA; Pérez-Sala, D | 1 |
| Chambers, S; Fraser, R; George, P; Lever, M; McEntyre, C; Slow, S; Vasudevamurthy, M | 1 |
| Austin, RC; Colgan, SM | 1 |
| Grotmol, T; Holm, PI; Hustad, S; Schneede, J; Ueland, PM; Vollset, SE | 1 |
| Beretich, GR | 1 |
| Bots, ML; Dalmeijer, GW; Olthof, MR; van der Schouw, YT; Verhoef, P | 1 |
| Benevenga, NJ | 1 |
| Blom, HJ; Clarke, R; de Groot, LC; Eussen, SJ; Hoefnagels, WH; Ueland, PM; van Staveren, WA | 1 |
| Cohn, J; Jiang, H; Maclean, KN; Mikael, LG; Rozen, R; Schwahn, BC; Wang, XL; Wu, Q | 1 |
| Chan, C; Ji, C; Kaplowitz, N; Kuhlenkamp, J; Shinohara, M | 1 |
| Atkinson, W; Chambers, ST; George, PM; Lever, M | 1 |
| Chiuve, SE; Dougherty, LW; Giovannucci, EL; Hankinson, SE; Rimm, EB; Willett, WC; Zeisel, SH | 1 |
| Atkinson, W; Chambers, ST; Downer, P; George, PM; Lever, M | 1 |
| Chen, T; Deaciuc, I; McClain, CJ; Song, Z; Zhou, Z | 1 |
| Castro, CC; Garrow, TA; Koutmos, M; Szegedi, SS | 1 |
| Bonham, MP; Clarkson, TW; Davidson, PW; Duffy, EM; McNulty, H; Molloy, AM; Myers, GJ; Robson, PJ; Scott, JM; Shamlaye, CF; Strain, J; Ueland, PM; Wallace, JM; Ward, M | 1 |
| Antonopoulou, S; Detopoulou, P; Panagiotakos, DB; Pitsavos, C; Stefanadis, C | 1 |
| Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M | 1 |
| Deng, L; Knock, E; Lawrance, AK; Rozen, R; Wang, XL; Wu, Q | 1 |
| Bleie, Ø; Konstantinova, SV; Nygård, O; Tell, GS; Ueland, PM; Vollset, SE | 1 |
| Morita, T; Ohuchi, S; Setoue, M; Sugiyama, K | 2 |
| Elmslie, J; Lever, M; Slow, S | 2 |
| Abratte, CM; Caudill, MA; Hung, J; Li, R; Moriarty, DJ; Wang, W | 1 |
| Abratte, CM; Caudill, MA; Li, R; Maletz, CV; Solis, C; Veenema, K; Wang, W | 1 |
| BORSOOK, H; DUBNOFF, JW | 1 |
| Ito, T; Ohkubo, Y; Sugiyama, N; Sumi, S; Togari, H; Ueta, A; Yokoi, K | 1 |
| Anandan, R; AnbinEzhilan, R; Buddhan, S; Ganesan, B; Sivakumar, R | 1 |
| Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M; Slow, S | 1 |
| Matsumoto, Y; Morita, T; Ohuchi, S; Sugiyama, K | 1 |
| Kharbanda, KK | 1 |
| Berk, O; Blom, HJ; Coker, M; Koroğlu, OA; Kültürsay, N; Ucar, SK; Yalaz, M | 1 |
| Chambers, ST; Elmslie, JL; Fink, JN; George, PM; Lever, M; Richards, AM; Scott, RS; Slow, S | 1 |
| Davidson, MH | 1 |
| Cho, E; Dougherty, L; Giovannucci, E; Jacques, PF; Lee, JE; Selhub, J; Zeisel, SH | 1 |
| Caudill, MA; Christensen, KE; Deng, L; Rozen, R; Wang, X; Wu, Q | 1 |
| Garrow, TA; Gupta, S; Jiracek, J; Kruger, WD; Li, L; Rozen, R; Schalinske, KL; Strakova, J; Williams, KT | 1 |
| Alfthan, G; Aro, A; Schwab, U; Uusitupa, M | 1 |
| Hamill, LL; Keaveney, EM; McNulty, H; Parker, MJ; Price, RK; Strain, JJ; Ueland, PM; Wallace, JM; Ward, M; Welch, RW | 1 |
| Goyke, E; Sledzinski, T; Sledzinski, Z; Smolenski, RT; Swierczynski, J | 1 |
| Alirezaei, M; Ghayemi, Z; Jelodar, G; Nazifi, S; Niknam, P | 1 |
| Gong, XJ; Guo, M; Jing, LX; Li, D; Lun, YZ; Sun, SX; Sun, WP; Xiao, FC; Zhang, LB; Zhou, SS | 1 |
| Aman, P; Andersson, SO; Hallmans, G; Johansson, JE; Kamal-Eldin, A; Moazzami, AA; Zhang, JX | 1 |
| Alachkar, A; Lajin, B; Sakur, AA | 1 |
| Chambers, ST; George, PM; Lever, M; Slow, S | 1 |
| Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M | 1 |
| Allen, RH; Greiner, LS; Jiang, H; Maclean, KN; Stabler, SP | 1 |
| Boyd, RN; Davies, PS; Moxon-Lester, L; Obeid, R; Schoendorfer, NC; Sharp, N; Vitetta, L | 1 |
| Atkinson, W; Chambers, ST; Elmslie, JL; Frampton, CM; George, PM; Lever, M; Molyneux, SL; Richards, AM; Slow, S; Troughton, RW | 2 |
| Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Slow, S | 1 |
| Allen, RH; Jiang, H; Maclean, KN; Stabler, SP | 1 |
| Liu, Y; Liu, YQ; Morita, T; Sugiyama, K | 1 |
| Chambers, ST; George, PM; Lever, M; Lewis, JG; Storer, MK | 1 |
| Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
| Idris, S; McIlwee, A; Ukachukwu, V | 1 |
| Chai, GS; Cheng, XS; Jiang, X; Liu, GP; Ma, ZW; Ni, ZF; Wang, JZ; Wang, Q; Xie, AJ | 1 |
| Bonham, MP; Davidson, PW; Henderson, J; Kobrosly, RW; McAfee, AJ; McSorley, EM; Mulhern, MS; Myers, GJ; Shamlaye, CF; Strain, JJ; Thurston, SW; Ueland, PM; van Wijngaarden, E; Wallace, JM; Watson, GE | 1 |
| Chang, Y; Chen, L; Jin, T; Tan, Y; Wang, L; Wei, J; Zhu, H | 1 |
| Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH | 1 |
| Ballesteros, M; Berrocal-Zaragoza, MI; Cavallé-Busquets, P; Fernandez-Ballart, JD; Fernàndez-Roig, S; Murphy, MM; Salat-Batlle, J; Ueland, PM | 1 |
| Collin, SM | 1 |
| Cao, JM; Cao, Y; Gong, XJ; Guo, J; Guo, M; Li, D; Lun, YZ; Luo, N; Sun, WP; Tian, YJ; Zhou, SS | 1 |
| Chen, L; Chen, YM; Ling, WH; Tan, YZ; Wang, LJ; Wei, J; Yang, Y; Zhou, JY; Zhu, HL | 1 |
| Barski, R; Luvai, A; Narayanan, D; Sharma, R | 1 |
| Liu, YP; Yang, YL | 1 |
| Obeid, R | 1 |
| Adam, S; Almeida, MF; Carbasius Weber, E; Champion, H; Chan, H; Daly, A; Dixon, M; Dokoupil, K; Egli, D; Evans, S; Eyskens, F; Faria, A; Ferguson, C; Hallam, P; Heddrich-Ellerbrok, M; Jacobs, J; Jankowski, C; Lachmann, R; Lilje, R; Link, R; Lowry, S; Luyten, K; MacDonald, A; Maritz, C; Martins, E; Meyer, U; Müller, E; Murphy, E; Robertson, LV; Rocha, JC; Saruggia, I; Schick, P; Stafford, J; Stoelen, L; Terry, A; Thom, R; van den Hurk, T; van Rijn, M; van Teefelen-Heithoff, A; Webster, D; White, FJ; Wildgoose, J; Zweers, H | 1 |
| Benoist, JF; Cornec-Le Gall, E; De Parscau, L; Delmas, Y; Doucet, L; Fremeaux-Bacchi, V; Le Meur, Y; Ogier, H | 1 |
| Liu, XP; Lou, ZQ; Peng, MF; Qi, Y; Qian, X; Xie, Y; Zhan, BC | 1 |
| Bahous, RH; Bedell, BJ; Caudill, MA; Deng, L; Grand'maison, M; Jadavji, NM; Malysheva, O; Rozen, R | 1 |
| Bertoia, ML; Cooke, JP; Joosten, MM; Mittleman, MA; Mukamal, KJ; Pai, JK; Rimm, EB | 1 |
| Diamond, CE; Garrow, TA; Hladílková, J; Jiráček, J; Jungwirth, P; Koutmos, M; Mládková, J; Tryon, K; Yamada, K | 1 |
| Chambers, ST; Elmslie, JL; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Parry-Strong, A; Slow, S | 1 |
| Han, F; Huang, Z; Liu, Y; Lu, J; Sugiyama, K; Sun, L; Wang, Q | 1 |
| Kim, SK; Kim, YM; Kwak, HC; Oh, SJ | 1 |
| Berge, RK; Bjørndal, B; Lysne, V; Nordrehaug, JE; Nygård, O; Skorve, J; Vik, R | 1 |
| Hiramatsu, M; Kinoshita, S; Kunisawa, K; Nagao, M; Nakashima, N; Nomura, T | 1 |
| Benoist, JF; Blom, HJ; de Baulny, HO; de Vriese, AS; Esse, R; Gupta, S; Imbard, A; Kruger, W; Lebon, S; Schiff, M | 1 |
| Bertolo, RF; Brunton, JA; Harding, SV; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Anilkumar, N; Brandes, RP; Brewer, AC; Burr, S; Caldwell, A; Dew, T; Dong, X; Halket, J; Hughes, RD; Martin, D; Mistry, RK; Murray, TV; Quaglia, A; Sawyer, GJ; Schröder, K; Shah, AM; Sherwood, R | 1 |
| Cavallé-Busquets, P; Fernandez-Ballart, JD; Murphy, MM; Solé-Navais, P | 1 |
| Herrmann, W; Hurtig-Wennlöf, A; Nilsson, TK; Obeid, R; Owen, JR; Sjöström, M; Zeisel, S | 1 |
| Ahn, CW; Choi, YJ; Jun, DS; Kim, YC; Na, JD | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Bertics, SJ; Luchini, ND; White, HM; Zhang, Q | 1 |
| Chen, NN; Guo, M; Li, D; Sun, WP; Zhai, MZ; Zhou, SS; Zhou, Y | 1 |
| Aris, IM; Chong, MF; Chong, YS; Fortier, MV; Gluckman, PD; Godfrey, KM; Kramer, MS; Lee, YS; Quah, PL; Saw, SM; Tint, MT; van Lee, L; Yap, FK | 1 |
| Andria, G; Ben-Omran, TI; Blom, HJ; Chakrapani, AB; Chapman, KA; Crushell, E; de Almeida, IT; Henderson, MJ; Hochuli, M; Huemer, M; Janssen, MC; Kožich, V; Maillot, F; Mayne, PD; McNulty, J; Morris, AA; Morrison, TM; O'Sullivan, S; Ogier, H; Pavlíková, M; Santra, S; Terry, A; Yap, S | 1 |
| Bhadelia, RA; Johnson, EJ; Lichtenstein, AH; Roe, AJ; Rogers, GT; Rosenberg, IH; Scott, TM; Smith, CE; Zeisel, SH; Zhang, S | 1 |
| Ding, S; Sun, J; Wen, S; Zhou, J | 1 |
| Che, L; Chen, Y; Fang, Z; Feng, B; Li, J; Lin, Y; Liu, H; Mou, D; Wang, J; Xu, S | 1 |
| Ebihara, K; Shimada, R | 1 |
| Kang, SS; Rosenson, RS | 1 |
| Gylling, B; Häggström, J; Hallmans, G; Johansson, I; Midttun, Ø; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Ulvik, A; Van Guelpen, B | 1 |
| Chmurzynska, A; Malinowska, AM; Mlodzik, MA; Nowacka-Woszuk, J; Radziejewska, A; Szwengiel, A | 1 |
| Dahdoul, T; Nijhout, HF; Reed, MC; Sadre-Marandi, F | 1 |
| Ali, MA; Bakir, MB; Kamel, MA; Khalifa, EA; Refaat, R; Salama, MA | 1 |
| Chen, X; Chen, Z; Cui, C; Huang, F; Jiang, X; Niu, J; Sun, J | 1 |
| Cheng, ZY; Du, YF; Shi, HF; Wang, XL; Wei, Y; Wu, TC; Yang, J; Zuo, XF | 1 |
| Drobny, A; Fitzenberger, E; Hellmann, B; Meloh, H; Mueller, AS; van der Klis, JD; Wächtershäuser, E; Wenzel, U | 1 |
| Aldamiz-Echevarria, L; Brunet, D; Cano, A; Cathebras, P; Couce, ML; Dalmau, J; Damaj, L; Dobbelaere, D; Eyer, D; García-Cazorla, A; Gay, C; Guffon, N; Hiéronimus, S; Levrat, V; Maillot, F; Martinez-Pardo Casanova, M; Nadjar, Y; Peña-Quintana, L; Rigalleau, V; Schiff, M; Touati, G; Valayannopoulos, V | 1 |
| Akemokwe, FM; Ceesay, K; James, PT; Jawla, O; Mohammed, NI; Prentice, AM; Silver, MJ; Sise, EA; Sonko, B | 1 |
| Lamers, Y; Mujica-Coopman, MF; Schroder, TH; Sinclair, G; Tan, A; Vallance, HD | 1 |
| Ito, Y; Nishikubo, T; Nishimoto, E; Sakakibara, T | 1 |
| Braconnier, A; Desmons, A; Garnotel, R; Gillery, P; Jaisson, S; Rieu, P; Wynckel, A | 1 |
| Asamoah, A; De Biase, I; Gherasim, C; La'ulu, SL; Longo, N; Yuzyuk, T | 1 |
| Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Slavkovich, V; Uddin, MN | 1 |
| Bublil, EM; Glavin, F; Majtan, T; Park, I | 1 |
| Elango, R | 1 |
| Jiang, H; Maclean, KN; Mclagan, BM; Phinney, WN; Roede, JR; Stabler, SP | 1 |
| Fishchuk, L; Gorovenko, N; Medvedieva, N; Rossokha, Z; Sheyko, L | 1 |
| Caughey, SD; Dunn, IC; Maidin, MBM; McCormack, HA; Whenham, N; Wilson, PW | 1 |
| Asbaghi, O; Ashtary-Larky, D; Bagheri, R; Ghanavati, M; Kashkooli, S; Kooti, W; Mombaini, D; Tinsley, GM; Wong, A | 1 |
| Andraos, S; Cameron-Smith, D; Chia, PHP; D'Souza, RF; Gillies, NA; Knowles, SO; Milan, AM; Mitchell, CJ; Mitchell, SM; Ramzan, F; Roy, NC; Sharma, P; Sjödin, A; Wagner, KH; Zeng, N | 1 |
| Cameron-Smith, D; Franzke, B; Gillies, NA; Hofmann, M; Milan, AM; Oesen, S; Roy, NC; Schober-Halper, B; Strasser, EM; Tosevska, A; Wagner, KH; Wessner, B | 1 |
| Li, F; Li, J; Liu, Z; Yu, N | 1 |
| Lin, B; Liu, Q; Tao, Y | 1 |
| Chmurzynska, A; Muzsik-Kazimierska, A; Nikrandt, G; Szwengiel, A | 1 |
| Abobaker, H; Hu, Y; Idriss, AA; Omer, NA; Zhao, R | 1 |
| Cariou, B; Croyal, M; Gand, E; Goronflot, T; Hadjadj, S; Jacobi, D; Le May, C; Prieur, X; Ragot, S; Saulnier, PJ; Trochu, JN; Wargny, M | 1 |
| Broz, P; Racek, J; Rajdl, D; Stehlík, P; Trefil, L | 1 |
| Fishchuk, L; Gorovenko, N; Rossokha, Z; Yeroshkina, K | 1 |
| Arthurs, AL; Jankovic-Karasoulos, T; Roberts, CT; Smith, MD; Williamson, JM | 1 |
| Alberti, C; Benoist, JF; de Baulny, HO; Feillet, F; Garcia-Segarra, N; Guilmin-Crépon, S; Haignere, J; Imbard, A; Kaguelidou, F; Kuster, A; Magréault, S; Perronneau, I; Schiff, M; Schlemmer, D; Toumazi, A | 1 |
| Araki, T; Dogan, S; Fujioka, M; Hosokawa, T; Ichihashi, K; Ikegame, T; Itokawa, M; Jinde, S; Kasai, K; Kirihara, K; Kondo, S; Koshiyama, D; Marumo, K; Morita, K; Suga, M; Sugishita, K; Tada, M; Taniguchi, K | 1 |
| Chen, S; Fang, AP; He, TT; Huang, BX; Huang, RZ; Huang, ZH; Li, SY; Liu, XZ; Liu, ZY; Lu, XT; Luo, Y; Maierhaba, W; Mo, QW; Wang, YF; Wang, YN; Yang, MT; Zhang, XG; Zhu, HL | 1 |
| Asahina, M; Imaizumi, K; Kawano, M; Nakashima, S; Sakamoto, M; Sato, M; Shirouchi, B; Tanaka, Y; Tashiro, K; Yamaguchi, C | 1 |
| Fukuoka, H; Horiguchi, S; Kagawa, Y; Kawabata, T; Kubo, Y; Nishikawa, M; Shoji, K; Tajima, A | 1 |
| Du, YF; Gong, XL; Shi, HF; Wang, XL; Wei, Y; Wu, TC; Zhao, YY | 1 |
22 review(s) available for betaine and homocysteine
| Article | Year |
|---|---|
Betaine, metabolic by-product or vital methylating agent?
Topics: Alcohol Oxidoreductases; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Diet; Ethanol; Homocysteine; Humans; Liver; Methionine; Methotrexate; Methylation; Methyltransferases; Oxidation-Reduction; Rats; Tetrahydrofolates | 1983 |
Betaine therapy for homocystinuria.
Topics: Adult; Betaine; Child, Preschool; Female; Homocysteine; Homocystinuria; Humans; Male | 1984 |
Hyperhomocysteinaemia: a newly recognized risk factor for vascular disease.
Topics: Arteriosclerosis; Betaine; Coronary Disease; Folic Acid; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Methionine; Pyridoxine; Risk Factors; Vascular Diseases | 1994 |
Remethylation defects: guidelines for clinical diagnosis and treatment.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12 | 1998 |
Drugs affecting homocysteine metabolism: impact on cardiovascular risk.
Topics: Anticonvulsants; Betaine; Cardiovascular Diseases; Clinical Trials as Topic; Gonadal Steroid Hormones; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Lipotropic Agents; Risk Factors | 2002 |
Effects of betaine intake on plasma homocysteine concentrations and consequences for health.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Folic Acid; Homocysteine; Humans; Lipids | 2005 |
Betaine: a key modulator of one-carbon metabolism and homocysteine status.
Topics: Animals; Betaine; Carbon; Cholic Acids; Homocysteine; Humans; Lipids; Nutritional Physiological Phenomena | 2005 |
Betaine supplementation and blood lipids: fact or artifact?
Topics: Betaine; Cardiovascular Diseases; Dietary Supplements; Homocysteine; Humans; Lipids; Lipotropic Agents | 2006 |
The use of betaine in the treatment of elevated homocysteine.
Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation | 2006 |
Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum.
Topics: Animals; Betaine; Endoplasmic Reticulum; Gastrointestinal Agents; Gene Expression Profiling; Glutathione; Homocysteine; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Mice; Mitochondria, Liver; Oxidative Stress; Rats; Sterol Regulatory Element Binding Proteins; Tumor Necrosis Factor-alpha | 2006 |
Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism?
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Homocysteine; Hormones; Humans; Liver; Methionine; Promoter Regions, Genetic; Protein Folding; Structure-Activity Relationship | 2006 |
Alcoholic liver disease and methionine metabolism.
Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
Folate and B12 in prostate cancer.
Topics: Betaine; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Male; Meta-Analysis as Topic; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Vitamin B 12 | 2013 |
[Advances in the clinical and laboratory studies on methylmalonic aciduria combined with homocysteinemia type cblC].
Topics: Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Betaine; Carrier Proteins; Child; China; DNA Mutational Analysis; Gas Chromatography-Mass Spectrometry; Genotype; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Infant; Methylmalonic Acid; Mutation; Oxidoreductases; Vitamin B 12 | 2013 |
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine | 2013 |
Early pregnancy B vitamin status, one carbon metabolism, pregnancy outcome and child development.
Topics: Betaine; Carbon; Child; Child Development; Child, Preschool; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Trimester, Third; Sarcosine; Vitamin B 12 | 2016 |
Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency.
Topics: Betaine; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Humans; Methionine; Pyridoxine | 2017 |
Analytic Approaches for the Treatment of Hyperhomocysteinemia and Its Impact on Vascular Disease.
Topics: Animals; Betaine; Biomarkers; Cardiovascular Diseases; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Phenotype; Risk Factors; Tetrahydrofolates; Treatment Outcome | 2018 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
Effects of betaine supplementation on cardiovascular markers: A systematic review and Meta-analysis.
Topics: Betaine; Biomarkers; Cardiovascular Diseases; Dietary Supplements; Homocysteine; Humans; Triglycerides | 2022 |
Betaine consumption as a new clinical approach to treatment and prophylaxis of folate-related pathologies.
Topics: Amino Acids; Betaine; Betaine-Homocysteine S-Methyltransferase; Folic Acid; Homocysteine; Humans; Methionine | 2023 |
High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Neural Tube Defects; Pregnancy; Thymidylate Synthase; Vitamin B 12 | 2022 |
30 trial(s) available for betaine and homocysteine
| Article | Year |
|---|---|
Cerebrospinal fluid and plasma total homocysteine and related metabolites in children with cystathionine beta-synthase deficiency: the effect of treatment.
Topics: Adolescent; Analysis of Variance; Betaine; Central Nervous System Diseases; Child; Cystathionine beta-Synthase; Homocysteine; Humans; Infant; Substrate Specificity | 1997 |
No change in impaired endothelial function after long-term folic acid therapy of hyperhomocysteinaemia in haemodialysis patients.
Topics: Adult; Aged; Betaine; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Renal Dialysis | 1998 |
Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients.
Topics: Adult; Betaine; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Time Factors; Treatment Outcome | 1999 |
Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women.
Topics: Adult; Betaine; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Fasting; Female; Homocysteine; Humans; Male; Methionine; Placebos; Reference Values | 2003 |
Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Betaine; Choline; Coronary Angiography; Dietary Supplements; Drug Administration Schedule; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Methyltransferases; Middle Aged; Sarcosine; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2004 |
Dimethylglycine supplementation does not affect plasma homocysteine concentrations in pre-dialysis chronic renal failure patients.
Topics: Adult; Aged; Betaine; Homocysteine; Humans; Kidney Failure, Chronic; Methionine; Middle Aged; Renal Dialysis; Sarcosine | 2004 |
Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans.
Topics: Adult; Aged; Betaine; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Lipids; Lipotropic Agents; Male; Middle Aged; Phosphatidylcholines; Placebos; Risk Factors | 2005 |
Betaine concentration as a determinant of fasting total homocysteine concentrations and the effect of folic acid supplementation on betaine concentrations.
Topics: Administration, Oral; Aged; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged | 2005 |
Orally administered betaine has an acute and dose-dependent effect on serum betaine and plasma homocysteine concentrations in healthy humans.
Topics: Administration, Oral; Adult; Area Under Curve; Betaine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gastrointestinal Agents; Half-Life; Homocysteine; Humans; Intestinal Absorption; Male | 2006 |
Homocysteine remethylation in young broilers fed varying levels of methionine, choline, and betaine.
Topics: Animals; Betaine; Chickens; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation | 2006 |
Evidence of choline depletion and reduced betaine and dimethylglycine with increased homocysteine in plasma of children with cystic fibrosis.
Topics: Adolescent; Betaine; Case-Control Studies; Child; Choline Deficiency; Cystic Fibrosis; Homocysteine; Humans; Sarcosine | 2006 |
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.
Topics: Aging; Animal Feed; Animals; Betaine; Chickens; Choline; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation | 2006 |
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.
Topics: Aged; Attention; Betaine; Choline; Cognition; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Neuropsychological Tests; Psychomotor Performance; Sarcosine; Vitamin B 12; Vitamin B Complex | 2007 |
Effects of orange juice and proline betaine on glycine betaine and homocysteine in healthy male subjects.
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Betaine; Beverages; Citrus sinensis; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Homocysteine; Humans; Intestinal Absorption; Kinetics; Male; Middle Aged; Proline | 2007 |
Dietary and supplementary betaine: acute effects on plasma betaine and homocysteine concentrations under standard and postmethionine load conditions in healthy male subjects.
Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Betaine; Choline; Cross-Over Studies; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Homocysteine; Humans; Male; Methionine; Sarcosine; Statistics, Nonparametric | 2008 |
Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males.
Topics: Adult; Betaine; Biomarkers; Choline; Creatinine; Cross-Over Studies; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Lipids; Male; Sarcosine; Time Factors; Vitamin B 12; Young Adult | 2009 |
Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine.
Topics: Acute Coronary Syndrome; Aged; Betaine; Clofibric Acid; Cohort Studies; Diabetes Complications; Female; Homocysteine; Humans; Hypolipidemic Agents; Lipids; Male; S-Adenosylmethionine; Stroke | 2009 |
Long-term effect of betaine on risk factors associated with the metabolic syndrome in healthy subjects.
Topics: Adult; Betaine; Cholesterol, HDL; Double-Blind Method; Female; Homocysteine; Humans; Linear Models; Lipoproteins, LDL; Male; Metabolic Syndrome; Middle Aged; Risk Factors; Surveys and Questionnaires; Time Factors; Triglycerides; Young Adult | 2011 |
Consumption of wheat aleurone-rich foods increases fasting plasma betaine and modestly decreases fasting homocysteine and LDL-cholesterol in adults.
Topics: Adult; Aged; Betaine; Cholesterol, LDL; Fasting; Homocysteine; Humans; Middle Aged; Placebos; Single-Blind Method; Triticum | 2010 |
Nuclear magnetic resonance-based metabolomics enable detection of the effects of a whole grain rye and rye bran diet on the metabolic profile of plasma in prostate cancer patients.
Topics: 3-Hydroxybutyric Acid; Aged; Aged, 80 and over; Betaine; Cross-Over Studies; Diet; Homocysteine; Humans; Insulin; Magnetic Resonance Spectroscopy; Male; Metabolome; Metabolomics; Multivariate Analysis; Plant Preparations; Prostate-Specific Antigen; Prostatic Neoplasms; Sarcosine; Secale; Triticum; United States | 2011 |
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Northern Ireland; Nutritional Status; Patient Compliance; Postmenopause | 2012 |
Extreme urinary betaine losses in type 2 diabetes combined with bezafibrate treatment are associated with losses of dimethylglycine and choline but not with increased losses of other osmolytes.
Topics: Adult; Aged; Betaine; Bezafibrate; Choline; Diabetes Mellitus, Type 2; Female; Glycerylphosphorylcholine; Homocysteine; Humans; Hypolipidemic Agents; Inositol; Male; Middle Aged; Sarcosine; Taurine; Young Adult | 2014 |
Association between malnutrition and hyperhomocysteine in Alzheimer's disease patients and diet intervention of betaine.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Betaine; Case-Control Studies; Dementia; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Memory; Nerve Tissue Proteins; Risk Factors | 2017 |
Maternal methyl donor supplementation during gestation counteracts bisphenol A-induced oxidative stress in sows and offspring.
Topics: Actins; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Benzhydryl Compounds; Betaine; Catalase; Choline; Diet; Dietary Supplements; Female; Folic Acid; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Malondialdehyde; Maternal Nutritional Physiological Phenomena; Oxidative Stress; Phenols; Placenta; Pregnancy; Superoxide Dismutase; Swine; Vitamin B 12 | 2018 |
A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia.
Topics: Adolescent; Adult; Betaine; Dietary Supplements; Female; Folic Acid; Gambia; Homocysteine; Humans; Middle Aged; Nutritional Status; Riboflavin; Vitamin B 12; Young Adult | 2019 |
Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults.
Topics: Adult; Arsenic; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Folic Acid; Homocysteine; Humans; Methylation | 2021 |
Responsiveness of one-carbon metabolites to a high-protein diet in older men: Results from a 10-wk randomized controlled trial.
Topics: Aged; Betaine; Carbon; Choline; Diet; Diet, High-Protein; Folic Acid; Homocysteine; Humans; Male; Vitamin B Complex | 2021 |
Nutritional supplementation alters associations between one-carbon metabolites and cardiometabolic risk profiles in older adults: a secondary analysis of the Vienna Active Ageing Study.
Topics: Aged; Aging; Betaine; Carbon; Cardiovascular Diseases; Choline; Dietary Supplements; Female; Homocysteine; Humans; Male | 2022 |
Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial.
Topics: Betaine; Child; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Humans; Methionine; Prospective Studies; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2022 |
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial.
Topics: Adolescent; Adult; Aged; Betaine; Dietary Supplements; Double-Blind Method; East Asian People; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 12; Vitamin B Complex; Young Adult | 2023 |
200 other study(ies) available for betaine and homocysteine
| Article | Year |
|---|---|
The behavioral effects of L-methionine and related compounds in rats and mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Betaine; Brain; Brain Chemistry; Circadian Rhythm; Conditioning, Operant; Cysteine; Electroencephalography; Eye Movements; Histidine; Homocysteine; Methionine; Mice; Mice, Inbred C57BL; Niacinamide; Rats; Serine; Sleep; Sleep, REM; Wakefulness | 1975 |
Betaine-homocysteine methyltransferase in the fungus Aspergillus nidulans.
Topics: Aspergillus nidulans; Betaine; Homocysteine; Kinetics; Methylenetetrahydrofolate Dehydrogenase (NADP); Methyltransferases; Species Specificity | 1979 |
Plasmodium knowlesi: in vitro biosynthesis of methionine and thymidylic acid.
Topics: Animals; Betaine; Cells, Cultured; Choline; Erythrocytes; Folic Acid; Formaldehyde; Formyltetrahydrofolates; Haplorhini; Histidine; Homocysteine; Macaca mulatta; Methionine; Plasmodium; Sarcosine; Serine; Thymidine Monophosphate; Thymine Nucleotides | 1977 |
Anticonvulsant properties of betaine.
Topics: Animals; Anticonvulsants; Betaine; Electroshock; Female; Homocysteine; Mice; Pentylenetetrazole | 1979 |
[Methyls of biological importance].
Topics: Betaine; Carnitine; Choline; Dealkylation; Homocysteine; Humans; Lipid Metabolism; Methane; Methionine; Methylation; Phosphatidylcholines | 1979 |
An increased requirement for methionine by transformed rat liver epithelial cells in vitro.
Topics: Betaine; Cell Division; Cell Line; Cell Transformation, Neoplastic; Culture Media; Homocysteine; Methionine | 1978 |
Betaine:homocysteine methyltransferase--a new assay for the liver enzyme and its absence from human skin fibroblasts and peripheral blood lymphocytes.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chickens; Fibroblasts; Homocysteine; Humans; Liver; Lymphocytes; Methionine; Methyltransferases; Sheep; Skin | 1991 |
Transmethylation of homocysteine to methionine: efficiency in the rat and chick.
Topics: Animals; Betaine; Body Weight; Chickens; Choline; Diet; Homocysteine; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; Sarcosine; Tetrahydrofolates | 1985 |
Head group specificity in the requirement of phosphatidylcholine biosynthesis for very low density lipoprotein secretion from cultured hepatocytes.
Topics: Animals; Apolipoproteins; Betaine; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Deanol; Ethanolamine; Ethanolamines; Homocysteine; Lipoproteins; Lipoproteins, VLDL; Liver; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; Triglycerides | 1989 |
Free and protein-bound homocysteine and cysteine in cystathionine beta-synthase deficiency: interrelations during short- and long-term changes in plasma concentrations.
Topics: Adult; Betaine; Blood Proteins; Cystathionine beta-Synthase; Cysteine; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Kinetics; Male; Methionine; Protein Binding | 1989 |
Homocysteinemia: depressed plasma serine levels.
Topics: Adult; Betaine; Carbon-Oxygen Lyases; Child, Preschool; Folic Acid; Glycine; Homocysteine; Humans; Isoleucine; Kidney Transplantation; Lyases; Male; Serine | 1987 |
Methionine metabolism in mammals. The methionine-sparing effect of cystine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine; Cystathionine beta-Synthase; Cystine; Diet; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1988 |
Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients.
Topics: Adolescent; Adult; Betaine; Child; Cystathionine beta-Synthase; Cysteine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Male; Methionine; Middle Aged; Pyridoxine; Serine | 1985 |
Ethanol, the choline requirement, methylation and liver injury.
Topics: Animals; Betaine; Choline; Ethanol; Folic Acid; Homocysteine; Liver; Methionine; Methylation; Rats; Tetrahydrofolates | 1985 |
A study of the behavioral disruption of mice induced by l-methionine and related compounds.
Topics: Amphetamine; Animals; Behavior, Animal; Betaine; Chlorpromazine; Cystathionine; Folic Acid; Histidine; Homocysteine; Homoserine; Male; Mescaline; Methionine; Mice; N,N-Dimethyltryptamine; Niacinamide; Serine; Social Behavior | 1974 |
Effect of ketone bodies and ACTH on the transmethylation reaction (S-adenosyl methionine independent system) in rats. I.
Topics: Acetoacetates; Adrenocorticotropic Hormone; Animals; Betaine; Depression, Chemical; Drug Synergism; Homocysteine; Hydroxybutyrates; In Vitro Techniques; Male; Methylation; Rats; Transferases; Vitamin B 12 Deficiency | 1969 |
Convulsant activity of homocysteine and other short-chain mercaptoacids: protection therefrom.
Topics: Animals; Betaine; Central Nervous System Stimulants; Cysteine; Glycine; Homocysteine; Male; Methionine; Phenobarbital; Pyridoxine; Rats; Serine | 1969 |
Methionine metabolism in mammals: regulatory effects of S-adenosylhomocysteine.
Topics: Adenosine; Animals; Betaine; Chromatography, Gel; Cystathionine; Enzyme Activation; Homocysteine; Kinetics; Liver; Lyases; Methionine; Methyltransferases; Rats; Regression Analysis | 1974 |
[Protective action of silymarine in phalloidine intoxication in the mouse].
Topics: Animals; Arginine; Betaine; Female; Glycosides; Homocysteine; Lactones; Mice; Mycotoxins; Phalloidine; Silymarin; Structure-Activity Relationship; Thiazoles | 1974 |
Methionine metabolism in mammals: kinetic study of betaine-homocysteine methyltransferase.
Topics: Animals; Betaine; Buffers; Calcium Phosphates; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Cystine; Gels; Glycine; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Liver; Methionine; Methyltransferases; Rats | 1972 |
Betaine-homocysteine transmethylase in Pseudomonas denitrificans, a vitamin B 12 overproducer.
Topics: Betaine; Biological Assay; Cell-Free System; Chromatography, Paper; Culture Media; Enzyme Repression; Homocysteine; Hydrogen-Ion Concentration; Lactobacillus; Methionine; Methyltransferases; Mutation; Pantothenic Acid; Pseudomonas; Temperature; Vitamin B 12 | 1973 |
[Importance and regulation of the cobalamin-dependent methionine synthetase and the betaine: homocystein methyltransferase in methionine and tetrahydrofolic acid metabolism of the rat].
Topics: Animals; Betaine; Coenzyme A; Diet; Female; Folic Acid; Homocysteine; Kidney; Liver; Methionine; Methylation; Methyltransferases; Rats; Tetrahydrofolates; Vitamin B 12 | 1973 |
The effect of methionine on folic acid and histidine metabolism in perfused rat liver.
Topics: Animals; Betaine; Carbon Dioxide; Carbon Isotopes; Choline; Deficiency Diseases; Drug Synergism; Ethionine; Folic Acid; Formates; Glutamates; Histidine; Homocysteine; Liver; Male; Methionine; Oxidation-Reduction; Peptides; Perfusion; Rats; Tetrahydrofolates; Vitamin B 12 Deficiency | 1972 |
Methionine metabolism in mammals. Regulation of homocysteine methyltransferases in rat tissue.
Topics: Aging; Alloxan; Animals; Betaine; Chromatography, Gel; Cycloheximide; Cysteine; Dactinomycin; Dietary Proteins; Enzyme Induction; Enzyme Repression; Glucagon; Homocysteine; Hormones; Liver; Male; Methionine; Methyltransferases; Organ Specificity; Rats; Tetrahydrofolates; Ultracentrifugation | 1971 |
Homocysteine-induced convulsions in the rat: protection by homoserine, serine, betaine, glycine and glucose.
Topics: Animals; Betaine; Glucose; Glycine; Homocysteine; Male; Rats; Seizures; Serine; Time Factors | 1969 |
Pyridoxine effects on cystathionine synthase in rat liver.
Topics: Amino Acids; Animals; Betaine; Cysteine; Homocysteine; Homocystine; Hydro-Lyases; Liver; Male; Pyridoxal Phosphate; Stimulation, Chemical; Succinates; Transferases; Vitamin B 6 Deficiency | 1970 |
Deranged B 12 metabolism: effects on sulfur amino acid metabolism.
Topics: Adenosine Triphosphate; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Betaine; Brain Chemistry; Carbon Isotopes; Child, Preschool; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Isomerases; Kidney; Liver; Male; Malonates; Methionine; Methyltransferases; Transferases; Vitamin B 12 | 1970 |
Detection of several non-protein amino acids in the presence of protein amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Autoanalysis; Betaine; Chromatography; Homocysteine; Hydroxyproline; Isoleucine; Lysine; Methionine; Phenylalanine; Pimelic Acids; Proteins; Sarcosine; Taurine; Urea | 1971 |
Catabolism of betaine and its relationship to cobalamin overproduction.
Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12 | 1971 |
Pyridoxalphosphate and non-enzymatic synthesis of methionine.
Topics: Aluminum; Betaine; Catalysis; Chromatography, Thin Layer; Copper; Ferrocyanides; Homocysteine; Hydrogen-Ion Concentration; Methionine; Pyridoxal Phosphate | 1967 |
Ethionine and methionine biosynthesis in rat liver.
Topics: Animals; Betaine; Ethionine; Homocysteine; Liver; Male; Methionine; Methylation; Rats; Stereoisomerism; Stimulation, Chemical; Transferases | 1969 |
Growth-promoting and lipotropic effect of carnitine in rats fed diets limited in protein and methionine.
Topics: Amino Acids; Animals; Betaine; Carnitine; Choline; Growth; Homocysteine; Lipid Metabolism; Liver; Male; Methionine; Protein Deficiency; Quaternary Ammonium Compounds; Rats; Threonine | 1965 |
Further studies on the oxidation of betaine by a marine bacterium, Achromobacter cholinophagum.
Topics: Alcaligenes; Betaine; Formaldehyde; Glycine; Homocysteine; Oxidation-Reduction; Quaternary Ammonium Compounds; Water Microbiology | 1966 |
The effect of local application of homocysteine on neuronal activity in the central nervous system of the rat.
Topics: Animals; Betaine; Brain; Convulsants; Electrophysiology; Glutamates; Glutamic Acid; Homocysteine; Male; Neurons; Rats; Rats, Inbred Strains | 1982 |
Methotrexate hepatotoxicity.
Topics: Animals; Betaine; Cholesterol Esters; Folic Acid; Homocysteine; Lipotropic Agents; Liver; Male; Methionine; Methotrexate; Methylation; Rats; Tetrahydrofolates; Triglycerides | 1984 |
Betaine delays the onset of neurological impairment in nitrous oxide-induced vitamin B-12 deficiency in fruit bats.
Topics: Animals; Ataxia; Betaine; Body Weight; Chiroptera; Diet; Homocysteine; Methionine; Nitrous Oxide; Vitamin B 12 Deficiency | 1984 |
Homocystinuria--the effects of betaine in the treatment of patients not responsive to pyridoxine.
Topics: Amino Acids; Amino Acids, Sulfur; Betaine; Cystathionine beta-Synthase; Cysteine; Female; Homocysteine; Homocystinuria; Humans; Male; Pyridoxine; Vitamin B 12 | 1983 |
The effect of methotrexate on homocysteine methylating agents in rat liver.
Topics: Animals; Betaine; Folic Acid Antagonists; Homocysteine; Liver; Male; Methotrexate; Methylation; Rats; Rats, Inbred Strains; Tetrahydrofolates; Time Factors | 1982 |
Enzymatic determination of betaine in rat tissues.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chemical Phenomena; Chemistry; Homocysteine; Methyltransferases; Radioisotope Dilution Technique; Rats | 1981 |
Induction of betaine: homocysteine methyltransferase in some murine cells cultured in vitro.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Cell Line; Cells, Cultured; Cricetinae; Enzyme Induction; Fibroblasts; Homocysteine; Kinetics; L Cells; Leukemia L1210; Methionine; Methyltransferases; Mice | 1980 |
1H NMR determination of urinary betaine in patients with premature vascular disease and mild homocysteinemia.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Betaine; Creatinine; Glycine; Homocysteine; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Regression Analysis; Sarcosine; Vascular Diseases | 1995 |
Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism.
Topics: Adolescent; Adult; Aged; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chromatography; Creatinine; Cystathionine beta-Synthase; Female; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methionine; Methyltransferases; Middle Aged; Rats; Rats, Sprague-Dawley; Reference Values; Renal Insufficiency; Sarcosine; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Short term betaine therapy fails to lower elevated fasting total plasma homocysteine concentrations in hemodialysis patients maintained on chronic folic acid supplementation.
Topics: Adult; Aged; Betaine; Fasting; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Treatment Failure | 1995 |
[Homocystinuria: effectiveness of the treatment with pyridoxine, folic acid, and betaine].
Topics: Betaine; Child; Child, Preschool; Drug Evaluation; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Male; Pyridoxine | 1993 |
Homocysteine-dependent demethylation of trimethylselenonium ion and selenobetaine with methionine formation.
Topics: Animals; Betaine; Binding, Competitive; Cytosol; Homocysteine; Homocysteine S-Methyltransferase; Kinetics; Liver; Male; Methionine; Methylation; Methyltransferases; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenium Compounds | 1993 |
Treatment of hyperhomocyst(e)inemia: physiological basis.
Topics: Betaine; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 1996 |
Human homocysteine catabolism: three major pathways and their relevance to development of arterial occlusive disease.
Topics: Arterial Occlusive Diseases; Betaine; Homocysteine; Homocystinuria; Humans; Male; Serine | 1996 |
Hepatic betaine-homocysteine methyltransferase activity in the chicken is influenced by dietary intake of sulfur amino acids, choline and betaine.
Topics: Amino Acids, Sulfur; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chickens; Choline; Cystine; Diet; Dose-Response Relationship, Drug; Female; Homocysteine; Liver; Male; Methionine; Methyltransferases; Random Allocation | 1996 |
Long term treatment with betaine in methylenetetrahydrofolate reductase deficiency.
Topics: Appetite; Betaine; Female; Follow-Up Studies; Growth; Homocysteine; Humans; Infant; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors | 1996 |
Betaine for homocystinuria.
Topics: Arteriosclerosis; Betaine; Diarrhea; Gastrointestinal Diseases; Homocysteine; Homocystinuria; Humans; Nausea; Risk Factors | 1997 |
MR and proton MR spectroscopy of the brain in hyperhomocysteinemia caused by methylenetetrahydrofolate reductase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Brain; Brain Diseases, Metabolic; Energy Metabolism; Female; Follow-Up Studies; Homocysteine; Humans; Infant; Lipotropic Agents; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Methylenetetrahydrofolate Reductase (NADPH2); Nerve Fibers, Myelinated; Oxidoreductases Acting on CH-NH Group Donors; Treatment Outcome | 1997 |
Strategies for the treatment of cystathionine beta-synthase deficiency: the experience of the Willink Biochemical Genetics Unit over the past 30 years.
Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Female; Folic Acid; Gastrointestinal Agents; Genetic Testing; Homocysteine; Homocystinuria; Humans; Infant; Infant, Newborn; Male; Pregnancy; Pregnancy Complications; Pyridoxine; Treatment Failure; Treatment Outcome | 1998 |
Betaine in wine: answer to the French paradox?
Topics: Arterial Occlusive Diseases; Betaine; Homocysteine; Humans; Wine | 1999 |
Tissue factor pathway inhibitor levels in patients with homocystinuria.
Topics: Adult; Betaine; Biomarkers; Cystathionine beta-Synthase; Endothelium; Factor VII; Female; Fibrinolytic Agents; Heparin; Homocysteine; Homocystinuria; Homozygote; Humans; Lipoproteins; Male; Protein C; Pyridoxine; Serine Proteinase Inhibitors; Thrombomodulin; Thromboplastin; Vascular Diseases; Vitamin B 12 | 2000 |
Methionine transamination in patients with homocystinuria due to cystathionine beta-synthase deficiency.
Topics: Adolescent; Adult; Aged; Amination; Betaine; Child; Child, Preschool; Cystathionine beta-Synthase; Female; Homocysteine; Homocystinuria; Humans; Infant; Lipotropic Agents; Male; Methionine; Middle Aged; Transaminases | 2000 |
Methylenetetrahydrofolate reductase deficiency: importance of early diagnosis.
Topics: Betaine; Child, Preschool; Diagnosis, Differential; Fatal Outcome; Fibroblasts; Folic Acid; Hematinics; Homocysteine; Homocystinuria; Homozygote; Humans; Infant; Intellectual Disability; Lipotropic Agents; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Treatment Outcome | 2000 |
Betaine supplementation and plasma homocysteine in healthy volunteers.
Topics: Adolescent; Adult; Betaine; Dietary Supplements; Female; Homocysteine; Humans; Male | 2000 |
Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy.
Topics: Animals; Betaine; Homocysteine; Hyperlipidemias; Liver; Niacin; Rats; S-Adenosylmethionine | 2000 |
Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical mapping, and expression of the human and mouse genes.
Topics: Amino Acid Sequence; Amyloid; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chromosome Mapping; Chromosomes, Human, Pair 5; Homocysteine; Humans; In Situ Hybridization, Fluorescence; Methyltransferases; Mice; Molecular Sequence Data; Prion Proteins; Prions; Protein Precursors; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Two-Hybrid System Techniques | 2000 |
Prebiotic methylation and the evolution of methyl transfer reactions in living cells.
Topics: Betaine; Biological Evolution; Ethanolamine; Evolution, Chemical; Formaldehyde; Gas Chromatography-Mass Spectrometry; Glycine; Homocysteine; Methylation; Methyltransferases; Origin of Life; Sulfonium Compounds | 2000 |
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Betaine; Betaine-Homocysteine S-Methyltransferase; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methyltransferases; Middle Aged; Peritoneal Dialysis; Predictive Value of Tests; Pyridoxine; Renal Dialysis; Sarcosine; Uremia; Vitamin B 12; Zinc | 2001 |
Purification and kinetic properties of betaine-homocysteine methyltransferase from Aphanothece halophytica.
Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Chromatography, Agarose; Chromatography, Gel; Cyanobacteria; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methyltransferases; Molecular Weight; Sarcosine | 2001 |
Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks.
Topics: Animals; Betaine; Chickens; Chromatography, High Pressure Liquid; Coccidia; Coccidiosis; Epithelium; Female; Gastrointestinal Agents; Homocysteine; Intestines; Jejunum; Liver; Male; Models, Biological; S-Adenosylmethionine | 2001 |
Betaine and homocysteine concentrations in infant formulae and breast milk.
Topics: Animals; Betaine; Female; Homocysteine; Homocystinuria; Humans; Infant; Infant Food; Milk; Milk, Human | 2001 |
Chronic ethanol consumption increases homocysteine accumulation in hepatocytes.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alcohol Drinking; Animals; Betaine; Central Nervous System Depressants; Ethanol; Gastrointestinal Agents; Hepatocytes; Homocysteine; Male; Rats; Rats, Wistar | 2001 |
Betaine and homocysteine concentrations in foods.
Topics: Betaine; Food Analysis; Homocysteine | 2002 |
An indirect response model of homocysteine suppression by betaine: optimising the dosage regimen of betaine in homocystinuria.
Topics: Administration, Oral; Adolescent; Betaine; Child; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Female; Homocysteine; Homocystinuria; Humans; Male; Pyridoxine; Treatment Failure | 2002 |
Active-site-mutagenesis study of rat liver betaine-homocysteine S-methyltransferase.
Topics: Adenosine Deaminase; Amino Acid Sequence; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Binding Sites; Circular Dichroism; Homocysteine; Humans; Liver; Methyltransferases; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Sequence Alignment | 2003 |
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Dose-Response Relationship, Drug; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Mice; Mice, Knockout; Models, Biological; Oxidoreductases; Phosphorylcholine | 2003 |
Betaine supplementation lowers plasma homocysteine in healthy men and women.
Topics: Adult; Betaine; Blood Glucose; Blood Pressure; Body Mass Index; Diet; Dietary Supplements; Eating; Fasting; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Reference Values | 2003 |
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice.
Topics: Animals; Betaine; Central Nervous System Depressants; Disease Models, Animal; Endoplasmic Reticulum; Ethanol; Fatty Liver, Alcoholic; Gastrointestinal Agents; Gene Expression; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis | 2003 |
Betaine. Monograph.
Topics: Betaine; Cardiovascular Diseases; Fatty Liver; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Obesity | 2003 |
Limited effectiveness of betaine therapy for cystathionine beta synthase deficiency.
Topics: Betaine; Child, Preschool; Chromatography, High Pressure Liquid; Female; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Male; Methionine; Treatment Outcome | 2003 |
Transcriptional regulation of methionine synthase by homocysteine and choline in Aspergillus nidulans.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aspergillus nidulans; Base Sequence; Betaine; Choline; Cloning, Molecular; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Homocysteine; Methionine; Models, Biological; Molecular Sequence Data; RNA, Messenger; Transcription, Genetic | 2003 |
[Ethionine pancreatitis in the rat. II. Attempts to prevent ethionine injury by methionine, cysteine-homocysteine, choline and betaine].
Topics: Animals; Betaine; Choline; Cysteine; Ethionine; Homocysteine; Methionine; Pancreatitis; Rats | 1960 |
Spontaneous increase in the rate of formation of methionine from dimethylthetin and homocysteine in rat liver homogenates.
Topics: Animals; Betaine; Glycine; Homocysteine; Liver; Methionine; Rats | 1951 |
Betaine analogues alter homocysteine metabolism in rats.
Topics: Animals; Betaine; Homocysteine; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Lew | 2004 |
Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.
Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Enzyme Inhibitors; Glutamic Acid; Homocysteine; Humans; Kinetics; Ligands; Methionine; Methyltransferases; Mutagenesis, Site-Directed; Protein Binding; Sarcosine; Spectrometry, Fluorescence; Substrate Specificity; Tryptophan; Tyrosine | 2004 |
Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency.
Topics: Animal Feed; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Cysteine; Female; Heterozygote; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Liver; Male; Methionine; Methyltransferases; Mice; Mice, Inbred C57BL; Regression Analysis; Serine | 2004 |
Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency.
Topics: Animals; Animals, Suckling; Betaine; Body Weight; Brain; Disease Models, Animal; Female; Genotype; Homocysteine; Homocystinuria; Lactation; Liver; Male; Maternal-Fetal Exchange; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Organ Size; Pregnancy | 2004 |
The effect of low doses of betaine on plasma homocysteine in healthy volunteers.
Topics: Adult; Betaine; Dose-Response Relationship, Drug; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Lipotropic Agents; Male; Middle Aged | 2004 |
Betaine and folate status as cooperative determinants of plasma homocysteine in humans.
Topics: Adult; Aged; Betaine; Choline; Creatinine; Dose-Response Relationship, Drug; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6 | 2005 |
Homocysteine, glycine betaine, and N,N-dimethylglycine in patients attending a lipid clinic.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Betaine; Carnitine; Creatinine; Female; Homocysteine; Humans; Male; Middle Aged; Regression Analysis; Sarcosine; Sex Characteristics; Vascular Diseases | 2005 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Effects of intravenous betaine on methionine-loading-induced plasma homocysteine elevation in rats.
Topics: Animals; Betaine; Disease Models, Animal; Glycine; Homocysteine; Hyperhomocysteinemia; Injections, Intravenous; Male; Methionine; Rats; Sarcosine | 2004 |
cblE type of homocystinuria due to methionine synthase reductase deficiency: functional correction by minigene expression.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Betaine; Brain; Cell Line, Transformed; Codon, Nonsense; DNA Mutational Analysis; Ferredoxin-NADP Reductase; Fibroblasts; Folic Acid; Genes, Synthetic; Genetic Complementation Test; Genetic Therapy; Haplotypes; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Mutation, Missense; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Recombinant Fusion Proteins; Sequence Deletion; Transfection; White People | 2005 |
Executive dysfunction in hyperhomocystinemia responds to homocysteine-lowering treatment.
Topics: Adult; Anticoagulants; Betaine; Cognition Disorders; Confusion; Disease Progression; Drug Therapy, Combination; Folic Acid; Frontal Lobe; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Remission Induction; Seizures; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2005 |
Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy.
Topics: Adult; Africa, Western; Betaine; Black People; Choline; Dietary Supplements; Female; Folic Acid; Gestational Age; Hematinics; Homocysteine; Humans; Netherlands Antilles; Nutritional Status; Postpartum Period; Predictive Value of Tests; Pregnancy; Regression Analysis | 2005 |
Maculopathy and retinal degeneration in cobalamin C methylmalonic aciduria and homocystinuria.
Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Cobamides; Female; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant; Macula Lutea; Methionine; Methylmalonic Acid; Retina; Retinal Degeneration; Vision, Ocular; Visual Acuity; Vitamin B 12 Deficiency | 2005 |
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12 | 2005 |
[Untreated homocystinuria in adulthood].
Topics: Adult; Age Factors; Angina Pectoris; Betaine; Diagnosis, Differential; Drug Therapy, Combination; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Intervertebral Disc Displacement; Lens Subluxation; Male; Marfan Syndrome; Myopia; Osteoporosis; Retinal Detachment; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2005 |
Homocysteine metabolism in ZDF (type 2) diabetic rats.
Topics: Animals; Betaine; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression Regulation, Enzymologic; Hepatocytes; Homocysteine; Insulin Resistance; Liver; Methionine; Phosphatidylcholines; Rats; Rats, Zucker; RNA, Messenger | 2005 |
Diagnostic significance of urinary thiodiglycolic acid as a possible tool for studying the role of vitamins B12 and folates in the metabolism of thiolic substances.
Topics: Adult; Betaine; Biomarkers; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Leucovorin; Male; Sulfhydryl Compounds; Thioglycolates; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Betaine; Choline; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Sex Factors; Surveys and Questionnaires; Vitamin B Complex | 2006 |
Hyperhomocysteinemia can be ameliorated by dimethylsulfoniopropionate in place of folic acid in mice.
Topics: Animals; Betaine; Chromatography, High Pressure Liquid; Folic Acid; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Kinetics; Male; Mice; Mice, Inbred ICR; Sulfonium Compounds | 2006 |
Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model.
Topics: Alanine Transaminase; Animals; Betaine; Biosynthetic Pathways; Central Nervous System Depressants; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Ethanol; Fatty Liver, Alcoholic; Heat-Shock Proteins; Homocysteine; Hyperhomocysteinemia; Lipogenesis; Lipotropic Agents; Liver; Mice; Mice, Knockout; Models, Animal; Molecular Chaperones; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Triglycerides | 2006 |
Effects of chronic betaine ingestion on methionine-loading induced plasma homocysteine elevation in rats.
Topics: Analysis of Variance; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Carnitine; Choline; Gastrointestinal Agents; Homocysteine; Injections, Intravenous; Liver; Male; Methionine; Rats; Rats, Wistar; Time Factors | 2006 |
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
Topics: Betaine; Carbon; DNA Methylation; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Kinetics; Mathematics; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Molecular Biology; Nutritional Physiological Phenomena; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polymorphism, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2006 |
Dimethylthetin treatment causes diffuse alveolar lung damage: a pilot study in a sheep model of Continuous Ambulatory Peritoneal Dialysis (CAPD).
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Dialysis Solutions; Disease Models, Animal; Glycine; Homocysteine; Hyperhomocysteinemia; Nephrectomy; Peritoneal Dialysis, Continuous Ambulatory; Pilot Projects; Pulmonary Alveoli; Renal Insufficiency; Sheep; Substrate Specificity | 2007 |
Homocysteinylation of metallothionein impairs intracellular redox homeostasis: the enemy within!
Topics: Atherosclerosis; Betaine; Endothelium, Vascular; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Metallothionein; Oxidation-Reduction; Risk Factors; Vitamin B Complex | 2007 |
Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->t genotypes and B-vitamin status in a large-scale epidemiological study.
Topics: Betaine; Choline; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins | 2007 |
Betaine may act as a fast-acting antipsychotic by rapidly reducing blood levels of homocysteine.
Topics: Administration, Oral; Antipsychotic Agents; Betaine; Dose-Response Relationship, Drug; Homocysteine; Humans | 2007 |
Prospective study on dietary intakes of folate, betaine, and choline and cardiovascular disease risk in women.
Topics: Aged; Betaine; Cardiovascular Diseases; Choline; Cohort Studies; Diet; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Middle Aged; Netherlands; Nutrition Surveys; Odds Ratio; Postmenopause; Prospective Studies; Surveys and Questionnaires | 2008 |
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.
Topics: Betaine; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Neural Tube Defects; Nutritional Physiological Phenomena; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex | 2007 |
Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia.
Topics: Animals; Animals, Genetically Modified; Aorta; Apolipoprotein A-I; Betaine; Cholesterol; Disease Models, Animal; Fatty Liver; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Lipotropic Agents; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Time; Triglycerides; Tyrosine | 2007 |
Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.
Topics: Animals; Apolipoproteins B; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Fatty Liver; Gene Transfer Techniques; Hepatocytes; Homocysteine; Humans; Lipid Metabolism; Liver Neoplasms; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Sterol Regulatory Element Binding Protein 1 | 2007 |
Sex differences in the control of plasma concentrations and urinary excretion of glycine betaine in patients attending a lipid disorders clinic.
Topics: Adult; Betaine; Betaine-Homocysteine S-Methyltransferase; Carnitine; Female; Homocysteine; Humans; Lipid Metabolism Disorders; Male; Middle Aged; Sarcosine; Sex Factors; Thyroid Hormones | 2007 |
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
Topics: Adult; Alcohol Drinking; Betaine; Biomarkers; Choline; Cross-Sectional Studies; Diet Records; Female; Folic Acid; Homocysteine; Humans; Linear Models; Lipotropic Agents; Methylation; Middle Aged; Predictive Value of Tests; Surveys and Questionnaires; Vitamin B Complex | 2007 |
Inhibition of adiponectin production by homocysteine: a potential mechanism for alcoholic liver disease.
Topics: Adiponectin; Adipose Tissue; Animals; Betaine; Cystathionine beta-Synthase; Disease Models, Animal; Endoplasmic Reticulum; Ethanol; Homocysteine; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methionine; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Rats; Rats, Sprague-Dawley | 2008 |
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Homocysteine; Homocysteine S-Methyltransferase; Humans; Metalloproteins; Methylation; Recombinant Proteins; S-Adenosylmethionine; Sarcosine; Substrate Specificity; Vitamin U; Zinc | 2008 |
Is there a new component of the Mediterranean diet that reduces inflammation?
Topics: Betaine; Biomarkers; Choline; Confounding Factors, Epidemiologic; Diet Surveys; DNA Methylation; Epigenesis, Genetic; Feeding Behavior; Female; Greece; Homocysteine; Humans; Inflammation; Life Style; Male; Mediterranean Region; Promoter Regions, Genetic; United States | 2008 |
Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study.
Topics: Adult; Betaine; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methionine; Parturition; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Third; Seychelles; Vitamin B 12; Vitamin B Complex | 2008 |
Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Betaine; Biomarkers; C-Reactive Protein; Choline; Cross-Sectional Studies; Diet Surveys; Fasting; Feeding Behavior; Female; Greece; Homocysteine; Humans; Inflammation; Interleukin-6; Life Style; Lipotropic Agents; Male; Middle Aged; Tumor Necrosis Factor-alpha | 2008 |
Strain differences in mice highlight the role of DNA damage in neoplasia induced by low dietary folate.
Topics: Animals; Betaine; Diet; DNA Damage; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Genotype; Homocysteine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; RNA, Messenger; Thymine Nucleotides; Uridine Triphosphate | 2008 |
Divergent associations of plasma choline and betaine with components of metabolic syndrome in middle age and elderly men and women.
Topics: Aged; Betaine; Blood Glucose; Blood Pressure; Body Composition; Body Mass Index; Body Weights and Measures; Choline; Exercise; Female; Homocysteine; Humans; Lipids; Male; Metabolic Syndrome; Middle Aged; Triglycerides | 2008 |
Hyperhomocysteinemia induced by guanidinoacetic acid is effectively suppressed by choline and betaine in rats.
Topics: Animals; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Glycine; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Rats | 2008 |
Dietary betaine and inflammation.
Topics: Age Factors; Betaine; Biological Availability; Diet; Ethnicity; Homocysteine; Humans; Inflammation | 2008 |
Ethnicity and folate influence choline status in young women consuming controlled nutrient intakes.
Topics: Adolescent; Adult; Betaine; Black or African American; Body Mass Index; Choline; Diet; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mexican Americans; Middle Aged; Phosphatidylcholines; Sphingomyelins; White People | 2008 |
Adequate Intake levels of choline are sufficient for preventing elevations in serum markers of liver dysfunction in Mexican American men but are not optimal for minimizing plasma total homocysteine increases after a methionine load.
Topics: Adolescent; Adult; Betaine; Choline; Genotype; Hispanic or Latino; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Reference Values | 2008 |
Dimethylthetin as a methylator of homocysteine.
Topics: Betaine; Cysteine; Glycine; Homocysteine; Humans | 1948 |
Choline deprivation induces hyperhomocysteinemia in rats fed low methionine diets.
Topics: Animals; Betaine; Choline; Choline Deficiency; Cysteine; Dietary Supplements; Growth; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Liver; Male; Methionine; Rats; Rats, Wistar | 2008 |
Long follow up of betaine therapy in two Japanese siblings with cystathionine beta-synthase deficiency.
Topics: Adolescent; Betaine; Cystathionine beta-Synthase; Female; Gastrointestinal Agents; Homocysteine; Homocystinuria; Humans; Methionine; Siblings | 2008 |
Antioxidant defense of betaine against isoprenaline-induced myocardial infarction in rats.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Aspartate Aminotransferases; Betaine; Catalase; Creatine Kinase; Glutathione Transferase; Homocysteine; Isoproterenol; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Myocardial Infarction; Myocardium; Rats; Spectrophotometry, Ultraviolet; Superoxide Dismutase | 2010 |
High casein diet decreases plasma homocysteine concentration in rats.
Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Diet; Dose-Response Relationship, Drug; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2009 |
Titration of betaine therapy to optimize therapy in an infant with 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Betaine; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Lipotropic Agents; Male; Time Factors | 2010 |
A clinical puzzle: fibrates and homocysteine elevation: editorial to: "fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine" by M. Lever et al.
Topics: Animals; Betaine; Bezafibrate; Clofibric Acid; Dyslipidemias; Folic Acid; Homocysteine; Humans; Hypolipidemic Agents; Metabolic Syndrome | 2009 |
Are dietary choline and betaine intakes determinants of total homocysteine concentration?
Topics: Betaine; Cardiovascular Diseases; Choline; Cognition Disorders; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Vitamin B 12; Vitamin B 6 | 2010 |
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carbon; Choline; Diet; Fatty Liver; Female; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; RNA, Messenger; Sex Factors | 2010 |
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Diet; Enzyme Inhibitors; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Betaine supplementation and the metabolic syndrome.
Topics: Betaine; Female; Homocysteine; Humans; Lipoproteins, LDL; Male; Metabolic Syndrome | 2011 |
Decreased serum betaine concentrations in patients after bariatric surgery.
Topics: Adult; Bariatric Surgery; Betaine; Female; Homocysteine; Humans; Male; Middle Aged; Obesity | 2011 |
Betaine prevents ethanol-induced oxidative stress and reduces total homocysteine in the rat cerebellum.
Topics: Animals; Antioxidants; Betaine; Catalase; Cerebellum; Ethanol; Glutathione Peroxidase; Homocysteine; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2011 |
Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives.
Topics: Adult; Betaine; Blood Pressure; Catecholamines; Female; Homocysteine; Humans; Hypertension; Indicators and Reagents; Male; Methylation; Niacinamide; Vitamins | 2012 |
Triplex tetra-primer ARMS-PCR method for the simultaneous detection of MTHFR c.677C>T and c.1298A>C, and MTRR c.66A>G polymorphisms of the folate-homocysteine metabolic pathway.
Topics: Betaine; DNA Primers; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Homocysteine; Humans; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide | 2012 |
Betaine excretion correlates with plasma homocysteine when plasma lipids are elevated.
Topics: Aged; Betaine; Cholesterol; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Lipids; Male; Metabolic Syndrome; Middle Aged | 2012 |
Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Blood Coagulation; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Models, Animal; Homocysteine; Homocystinuria; Interleukin-1beta; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Thrombosis; Tumor Necrosis Factor-alpha | 2012 |
Methylation capacity in children with severe cerebral palsy.
Topics: Betaine; Biomarkers; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Choline; Cystathionine; DNA Methylation; Erythrocyte Indices; Erythrocyte Membrane; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Queensland; Severity of Illness Index; Uric Acid | 2012 |
The contrasting relationships between betaine and homocysteine in two clinical cohorts are associated with plasma lipids and drug treatments.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Betaine; Cholesterol; Cohort Studies; Female; Homocysteine; Hospitalization; Humans; Lipid Metabolism Disorders; Lipids; Male; Middle Aged; Models, Biological; Reproducibility of Results; Research Design; Vascular Diseases | 2012 |
Variability of plasma and urine betaine in diabetes mellitus and its relationship to methionine load test responses: an observational study.
Topics: Aged; Betaine; Biomarkers; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Glycosuria; Homocysteine; Humans; Linear Models; Male; Methionine; Middle Aged; New Zealand; Predictive Value of Tests; Reproducibility of Results; Sarcosine; Time Factors | 2012 |
Altered expression of apoA-I, apoA-IV and PON-1 activity in CBS deficient homocystinuria in the presence and absence of treatment: possible implications for cardiovascular outcomes.
Topics: Adolescent; Adult; Animals; Apolipoprotein A-I; Apolipoproteins A; Aryldialkylphosphatase; Betaine; Brain; Carboxylic Ester Hydrolases; Child; Child, Preschool; Dietary Supplements; Disease Models, Animal; Homocysteine; Homocystinuria; Humans; Lipotropic Agents; Liver; Male; Mice; Mice, Knockout; Young Adult | 2012 |
Betaine and secondary events in an acute coronary syndrome cohort.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Betaine; Chromatography, High Pressure Liquid; Cohort Studies; Female; Heart Failure; Homocysteine; Humans; Kaplan-Meier Estimate; Linear Models; Male; Middle Aged; Myocardial Infarction; New Zealand; Risk Factors; Sarcosine | 2012 |
Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline Deficiency; Dietary Supplements; Enzyme Inhibitors; Folic Acid; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Wistar; Sarcosine | 2012 |
Plasma betaine concentrations correlate with plasma cortisol but not with C-reactive protein in an elderly population.
Topics: Aged; Aged, 80 and over; Betaine; C-Reactive Protein; Carnitine; Female; Hip Fractures; Homocysteine; Humans; Hydrocortisone; Male; Regression Analysis | 2012 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
Acute myocardial infarction in a young patient with hyperhomocysteinaemia.
Topics: Acute Disease; Adult; Betaine; Coronary Vessels; Folic Acid; Heart; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Myocardium; Thrombosis; Troponin; Ventricular Function, Left | 2012 |
Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.
Topics: Alzheimer Disease; Animals; Betaine; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Male; Memory Disorders; Rats; Rats, Sprague-Dawley | 2013 |
Choline status and neurodevelopmental outcomes at 5 years of age in the Seychelles Child Development Nutrition Study.
Topics: Betaine; Child Development; Child, Preschool; Choline; Cognition; Female; Homocysteine; Humans; Language; Linear Models; Longitudinal Studies; Male; Methionine; Neuropsychological Tests; Nutritional Status; Pregnancy; Sarcosine; Seychelles | 2013 |
Betaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter.
Topics: Animals; Apolipoproteins E; Betaine; Carnitine O-Palmitoyltransferase; Choline; Cytochrome P-450 CYP2E1; DNA Methylation; Fatty Acid Synthase, Type I; Food, Formulated; Gene Expression Regulation; Glutathione Peroxidase; Homocysteine; Lipid Metabolism; Lipotropic Agents; Liver; Male; Mice; Mice, Inbred C57BL; PPAR alpha; Promoter Regions, Genetic; Signal Transduction; Superoxide Dismutase; Triglycerides | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.
Topics: Adult; Betaine; Choline; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Nutritional Status; Pregnancy; Sarcosine; Spain; Vitamin B 12 | 2013 |
Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats.
Topics: Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA; DNA Damage; DNA Methylation; Epigenesis, Genetic; Glucose Intolerance; Homocysteine; Insulin Resistance; Liver; Male; Metabolic Diseases; Niacin; Niacinamide; Oxidative Stress; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Time Factors; Uracil; Vitamin B Complex; Weight Gain | 2013 |
Higher homocysteine and lower betaine increase the risk of microangiopathy in patients with diabetes mellitus carrying the GG genotype of PEMT G774C.
Topics: Adult; Aged; Aged, 80 and over; Betaine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Genotype; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide | 2013 |
Stroke in a young man.
Topics: Adult; Betaine; Cystathionine beta-Synthase; Diet, Protein-Restricted; Homocysteine; Homocystinuria; Humans; Lipotropic Agents; Male; Methionine; Platelet Aggregation Inhibitors; Pyridoxine; Stroke; Treatment Outcome; Vision Disorders; Vitamin B Complex | 2013 |
Dietary practices in pyridoxine non-responsive homocystinuria: a European survey.
Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Diet, Protein-Restricted; Europe; Female; Homocysteine; Homocystinuria; Humans; Infant; Male; Methionine; Pyridoxine; Surveys and Questionnaires; Treatment Outcome | 2013 |
Adult-onset eculizumab-resistant hemolytic uremic syndrome associated with cobalamin C deficiency.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Antibodies, Monoclonal, Humanized; Betaine; Biopsy; Carrier Proteins; Diagnosis, Differential; Drug Resistance; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Hypertension, Malignant; Immunologic Factors; Kidney; Kidney Function Tests; Leucovorin; Lipotropic Agents; Male; Methionine; Methylmalonic Acid; Mutation; Oxidoreductases; Recurrence; Renal Dialysis; Treatment Outcome; Vitamin B 12 Deficiency; Vitamin B Complex | 2014 |
Betaine suppressed Aβ generation by altering amyloid precursor protein processing.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Betaine; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Homocysteine; Humans; L-Lactate Dehydrogenase; Lipotropic Agents; Mice; Mutation; Neuroblastoma; Transfection | 2014 |
Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism.
Topics: Acetylcholinesterase; Animals; Apoptosis; Betaine; Cerebellum; Choline; Choline O-Acetyltransferase; Disease Models, Animal; DNA Methylation; Ferredoxin-NADP Reductase; Gene Expression; Hippocampus; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Male; Memory, Short-Term; Methionine; Mice; Mice, Knockout; Synaptic Transmission | 2014 |
Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease.
Topics: Adult; Aged; Betaine; Case-Control Studies; Choline; Cohort Studies; Diet; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B Complex | 2014 |
Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase.
Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Databases, Protein; Enzyme Activation; Homocysteine; Humans; Kinetics; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutant Proteins; Potassium; Protein Conformation; Recombinant Proteins; Substrate Specificity | 2014 |
[Betaine-enriched beet suppresses hyperhomocysteinemia induced by choline deficiency in rats].
Topics: Amino Acids; Animals; Beta vulgaris; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Choline Deficiency; Cysteine; Diet; Dietary Supplements; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Rats; Rats, Wistar | 2015 |
Sulfur amino acid metabolism in Zucker diabetic fatty rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Cysteine; Dipeptides; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Homocysteine; Liver; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine; Spermine; Taurine | 2015 |
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6 | 2015 |
Betaine prevents homocysteine-induced memory impairment via matrix metalloproteinase-9 in the frontal cortex.
Topics: Animals; Betaine; Drug Interactions; Frontal Lobe; Homocysteine; Hyperhomocysteinemia; Lipopolysaccharides; Male; Matrix Metalloproteinase 9; Memory Disorders; Mice | 2015 |
High homocysteine induces betaine depletion.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carrier Proteins; Disease Models, Animal; Female; GABA Plasma Membrane Transport Proteins; Homocysteine; Homocystinuria; Humans; Male; Mice; Mice, Transgenic; Rats; Rats, Wistar | 2015 |
Betaine is as effective as folate at re-synthesizing methionine for protein synthesis during moderate methionine deficiency in piglets.
Topics: Animals; Betaine; Carbon Isotopes; Choline; Cysteine; Diet; Dietary Supplements; Folic Acid; Homocysteine; Methionine; Models, Biological; Oxidation-Reduction; Phenylalanine; Protein Biosynthesis; Swine | 2016 |
NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Betaine; Blotting, Western; Cells, Cultured; Cysteine; Female; Glutathione; Hep G2 Cells; Homocysteine; Humans; Immunoenzyme Techniques; Liver; Liver Diseases; Methionine; Mice; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; S-Adenosylmethionine | 2015 |
Plasma 1-carbon metabolites and academic achievement in 15-yr-old adolescents.
Topics: Adolescent; Betaine; Choline; Cross-Sectional Studies; Educational Status; Female; Genotype; Homocysteine; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Single Nucleotide; Social Class; Surveys and Questionnaires | 2016 |
Alleviation of hepatic fat accumulation by betaine involves reduction of homocysteine via up-regulation of betaine-homocysteine methyltransferase (BHMT).
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Dietary Fats; Homocysteine; Humans; Liver; Male; Rats; Rats, Sprague-Dawley; Up-Regulation | 2016 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
The effect of increasing concentrations of dl-methionine and 2-hydroxy-4-(methylthio) butanoic acid on hepatic genes controlling methionine regeneration and gluconeogenesis.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Animals, Newborn; Betaine; Betaine-Homocysteine S-Methyltransferase; Carnitine O-Palmitoyltransferase; Cattle; Down-Regulation; Gluconeogenesis; Glucose-6-Phosphatase; Hepatocytes; Homocysteine; Liver; Methionine; Methionine Adenosyltransferase; Methylenetetrahydrofolate Reductase (NADPH2); Phosphoenolpyruvate Carboxykinase (GTP); S-Adenosylmethionine; Up-Regulation | 2016 |
Comparison of the effects of nicotinic acid and nicotinamide degradation on plasma betaine and choline levels.
Topics: Adult; Betaine; Blood Pressure; Choline; Dietary Supplements; Food, Fortified; Homocysteine; Humans; Hydrolysis; Kinetics; Male; Metanephrine; Methylation; Niacin; Niacinamide; Normetanephrine; Pyridones; Random Allocation; Young Adult | 2017 |
Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study.
Topics: Adipose Tissue; Adolescent; Adult; Betaine; Birth Weight; Body Composition; Body Mass Index; Choline; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Infant; Linear Models; Male; Methionine; Middle Aged; Nutritional Status; Prospective Studies; Sensitivity and Specificity; Singapore; Vitamin B 12; Young Adult | 2016 |
Choline and its metabolites are differently associated with cardiometabolic risk factors, history of cardiovascular disease, and MRI-documented cerebrovascular disease in older adults.
Topics: Aged; Aged, 80 and over; Betaine; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cerebrovascular Disorders; Cholesterol; Choline; Cross-Sectional Studies; Diabetes Mellitus; Female; Homocysteine; Humans; Hypertension; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphatidylcholines; Risk Factors; Triglycerides; Waist Circumference | 2017 |
Soybean amplifies the hypohomocysteinemic effect of betaine and improves its hypercholesterolemic effect.
Topics: Animal Feed; Animals; Betaine; Bile Acids and Salts; Body Weight; Caseins; Cholesterol; Feces; Gene Expression; Glycine max; Homocysteine; Hypercholesterolemia; Lecithins; Liver; Male; Organ Size; Rats, Wistar; Soybean Proteins; Triglycerides | 2018 |
One-carbon metabolite ratios as functional B-vitamin markers and in relation to colorectal cancer risk.
Topics: Betaine; Biomarkers, Tumor; Carbon; Case-Control Studies; Colorectal Neoplasms; Creatinine; Cysteine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Riboflavin; Vitamin B 12; Vitamin B Complex | 2019 |
Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model.
Topics: Animals; Betaine; Caloric Restriction; Carbon; Choline; DNA Methylation; Female; Gene Expression; Homocysteine; Hydrolases; Liver; Male; Methylamines; Models, Biological; Pregnancy; Pregnancy, Animal; Rats, Wistar; S-Adenosylmethionine | 2018 |
Sex differences in hepatic one-carbon metabolism.
Topics: Betaine; Carbon; Choline; Female; Folic Acid; Homocysteine; Humans; Liver; Male; Models, Biological; Sex Characteristics | 2018 |
Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease.
Topics: Animals; Betaine; Carbon; Choline; Diet, High-Fat; Dietary Supplements; DNA Methylation; Folic Acid; Glutathione; Homocysteine; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; S-Adenosylmethionine | 2019 |
Betaine ameliorates prenatal valproic-acid-induced autism-like behavioral abnormalities in mice by promoting homocysteine metabolism.
Topics: Animals; Antimanic Agents; Autism Spectrum Disorder; Behavior, Animal; Betaine; Disease Models, Animal; Female; Homocysteine; Mice; Mice, Inbred ICR; Pregnancy; Prenatal Exposure Delayed Effects; Protective Agents; Social Behavior; Valproic Acid | 2019 |
Maternal betaine status, but not that of choline or methionine, is inversely associated with infant birth weight.
Topics: Adult; Betaine; Birth Weight; Choline; Female; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Pregnancy Trimesters; Sarcosine | 2019 |
Betaine-rich sugar beet molasses protects from homocysteine-induced reduction of survival in Caenorhabditis elegans.
Topics: Animals; Betaine; Caenorhabditis elegans; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Homocysteine; Hot Temperature; Molasses; Stress, Physiological; Survival Analysis | 2020 |
Betaine anhydrous in homocystinuria: results from the RoCH registry.
Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Female; France; Homocysteine; Homocystinuria; Humans; Infant; Male; Registries; Retrospective Studies; Spain; Treatment Outcome; Young Adult | 2019 |
Serum Betaine and Dimethylglycine Are Higher in South Asian Compared with European Pregnant Women in Canada, with Betaine and Total Homocysteine Inversely Associated in Early and Midpregnancy, Independent of Ethnicity.
Topics: Adult; Betaine; Canada; Ethnicity; Europe; Female; Homocysteine; Humans; India; Pregnancy; Retrospective Studies; Sarcosine | 2019 |
Early treatment using betaine and methionine for a neonate with MTHFR deficiency.
Topics: Betaine; Homocysteine; Homocystinuria; Humans; Infant; Infant, Newborn; Japan; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Psychotic Disorders; Treatment Outcome | 2019 |
An unusually high plasma concentration of homocysteine resulting from a combination of so-called "secondary" etiologies.
Topics: Aged; Betaine; Female; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Leucovorin; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Psychotic Disorders; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2020 |
Laboratory evaluation of homocysteine remethylation disorders and classic homocystinuria: Long-term follow-up using a cohort of 123 patients.
Topics: Betaine; Cystathionine beta-Synthase; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Laboratories; Methionine; Methylation | 2020 |
Interplay of Enzyme Therapy and Dietary Management of Murine Homocystinuria.
Topics: Animals; Betaine; Cystathionine beta-Synthase; Enzyme Therapy; Female; Homocysteine; Homocystinuria; Humans; Male; Methionine; Mice; Recombinant Proteins | 2020 |
Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis.
Topics: Adenosylhomocysteinase; Animals; Betaine; Cystathionine beta-Synthase; Disease Models, Animal; Folic Acid; Gene Expression Regulation, Enzymologic; Glycine Hydroxymethyltransferase; Homocysteine; Homocystinuria; Humans; Liver; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Polyamines | 2021 |
POSITIVE EFFECT OF BETAINE-ARGININE SUPPLEMENT ON IMPROVED HYPERHOMOCYSTEINEMIA TREATMENT IN MARRIED COUPLES WITH REPRODUCTIVE DISORDERS.
Topics: Arginine; Betaine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12 | 2020 |
Dietary betaine reduces plasma homocysteine concentrations and improves bone strength in laying hens.
Topics: 6-Phytase; Animal Feed; Animals; Betaine; Chickens; Diet; Dietary Supplements; Female; Homocysteine; Phosphorus | 2021 |
The betaine-dependent remethylation pathway is a homocysteine metabolism pathway associated with the carnivorous feeding habits of spiders.
Topics: Animals; Betaine; Diet; Habits; Homocysteine; Mammals | 2022 |
Improved methylation in E. coli via an efficient methyl supply system driven by betaine.
Topics: Adenosine Triphosphate; Betaine; Escherichia coli; Homocysteine; Methylation; Methyltransferases; S-Adenosylmethionine | 2022 |
Lower plasma glutathione, choline, and betaine concentrations are associated with fatty liver in postmenopausal women.
Topics: Betaine; Biomarkers; Choline; Fatty Liver; Female; Folic Acid; Glutathione; Homocysteine; Humans; Postmenopause | 2022 |
In ovo injection of betaine promotes adrenal steroidogenesis in pre-hatched chicken fetuses.
Topics: Animals; Betaine; Chickens; Corticosterone; Fetus; Homocysteine | 2022 |
Nutritional biomarkers and heart failure requiring hospitalization in patients with type 2 diabetes: the SURDIAGENE cohort.
Topics: Aged; Betaine; Biomarkers; Carnitine; Choline; Cohort Studies; Cysteine; Diabetes Mellitus, Type 2; Female; Heart Failure; Homocysteine; Hospitalization; Humans; Male; Methionine; Middle Aged; Prospective Studies; Risk Factors | 2022 |
Effect of Beer Consumption on Methylation and Redox Metabolism.
Topics: Antioxidants; Apolipoproteins; Beer; Betaine; Cholesterol, LDL; Folic Acid; Homocysteine; Humans; Male; Methylation; Oxidation-Reduction; Superoxide Dismutase; Uric Acid; Vitamin B 6 | 2022 |
Betaine supplementation improves positive symptoms in schizophrenia.
Topics: Betaine; Dietary Supplements; Homocysteine; Humans; Methionine; Schizophrenia | 2022 |
Mutation in Smek2 regulating hepatic glucose metabolism causes hypersarcosinemia and hyperhomocysteinemia in rats.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Betaine; Glucose; Homocysteine; Hypercholesterolemia; Hyperhomocysteinemia; Liver; Mutation; Phosphoprotein Phosphatases; Rats; Rats, Inbred BN; Sarcosine; Sarcosine Dehydrogenase | 2023 |
Serum 5-Methyltetrahydrofolate Status Is Associated with One-Carbon Metabolism-Related Metabolite Concentrations and Enzyme Activity Indicators in Young Women.
Topics: Adolescent; Adult; Betaine; Carbon; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Pregnancy; S-Adenosylmethionine; Young Adult | 2023 |
[Association between maternal plasma one-carbon biomarkers during pregnancy and fetal growth in twin pregnancies].
Topics: Adult; Betaine; Biomarkers; Birth Weight; Choline; Cohort Studies; Female; Fetal Development; Fetal Weight; Homocysteine; Humans; Infant, Newborn; Methionine; Pregnancy; Pregnancy Outcome; Pregnancy Trimesters; Pregnancy, Twin | 2023 |