betaine has been researched along with folic acid in 206 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (14.56) | 18.7374 |
| 1990's | 14 (6.80) | 18.2507 |
| 2000's | 52 (25.24) | 29.6817 |
| 2010's | 85 (41.26) | 24.3611 |
| 2020's | 25 (12.14) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Poirier, LA | 1 |
| Canfield, CJ; McCormick, GJ; Smith, CC | 1 |
| Ammon, HV; Phillips, SF; Thomas, PJ | 1 |
| Chavez, E; Hafez, YS; Kratzer, FH; Vohra, P | 1 |
| Dudman, NP; Tyrrell, PA; Wilcken, DE | 2 |
| Barak, AJ; Beckenhauer, HC; Tuma, DJ | 2 |
| Poirier, LA; Whitehead, VM | 1 |
| Beaton, JM; Bradley, RJ; Bridgers, WF; McClain, LD; Pegram, GV; Smythies, JR | 1 |
| Howell, JN; Jaenicke, L; Sauer, H | 1 |
| Batra, KK; Buehring, KU; Stokstad, EL | 1 |
| Fuller, HL; Keshavarz, K | 1 |
| Allen, SH; Marston, HR | 1 |
| Levy, H; Morrow, G; Mudd, SH | 1 |
| Komrower, GM | 1 |
| Benevenga, NJ; Berlow, S; Smolin, LA | 1 |
| Allen, RH; Bostom, AG; Nadeau, MR; Selhub, J; Shemin, D; Shih, V; Stabler, SP | 1 |
| Allen, RH; Lindenbaum, J; Savage, DG; Stabler, SP | 1 |
| Boers, GH | 1 |
| Cabello Tomás, ML; Dalmau Serra, J; García Gómez, AM; Montero Brens, C; Rodes Monegal, M; Vilaseca Busca, A | 1 |
| Cooper, BA; Dilling, LA; Haworth, JC; Lue-Shing, H; Rosenblatt, DS; Seargeant, LE; Surtees, RA | 1 |
| Kang, SS | 1 |
| Albright, CD; Citarella, MT; da Costa, KA; Mar, MH; Shin, OH; Zeisel, SH | 1 |
| Donker, AJ; Jakobs, C; Janssen, MJ; Lambert, J; Stehouwer, CD; ter Wee, PM; van Guldener, C | 1 |
| Bridge, C; Till, J; Walter, JH; White, FJ; Wraith, JE | 1 |
| Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J | 1 |
| Cooney, CA; Kodell, RL; Moore, SR; Wolff, GL | 1 |
| de Meer, K; Donker, AJ; Janssen, MJ; Stehouwer, CD; van Guldener, C | 1 |
| Blom, HJ; Boers, GH; Cruysberg, JR; Kluijtmans, LA; Kraus, JP; Trijbels, FJ; van den Heuvel, LP | 1 |
| Bassan, H; Fattal-Valevski, A; Gutman, A; Harel, S; Korman, SH; Lerman-Sagie, T | 1 |
| Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Robson, RA | 2 |
| Boers, GH; Brenton, DP; Howard, PM; Lee, PJ; Naughten, ER; Walter, JH; Wilcken, B; Wilcken, DE; Yap, S | 1 |
| al-Essa, MA; Ozand, PT; Rashed, MS | 1 |
| Bodamer, OA; Smith, DL | 1 |
| Alfthan, G; Aro, A; Saarinen, M; Schwab, U; Toppinen, L; Törrönen, A; Uusitupa, M | 1 |
| Katan, MB; Steenge, GR; Verhoef, P | 1 |
| Jirtle, RL; Waterland, RA | 1 |
| ERICSON, LE; HARPER, AE | 1 |
| ANDERSON, EI; HSU, PT; STEKOL, JA; WATJEN, A; WEISS, S | 1 |
| BACQ, ZM; LIEBECQ-HUTTER, S | 1 |
| LIEBECQ-HUTTER, S | 1 |
| ROTZSCH, W; THOMITZEK, WD | 1 |
| HOSEIN, EA | 1 |
| BRICTEUX-GREGOIRE, S; FLAMEE, P; LIEBECQ-HUTTER, S; VERLY, WG | 1 |
| KUNZ, W; STRACK, E | 1 |
| BALL, CR | 1 |
| STRACK, E; THOMITZEK, WD | 1 |
| GEER, BW; VOVIS, GF | 1 |
| HEUSER, GF; NORRIS, LC; YOUNG, RJ | 1 |
| KRAKE, JJ; MILLER, WL | 1 |
| Bleie, Ø; Holm, PI; Lien, EA; Nordrehaug, JE; Nygård, O; Refsum, H; Ueland, PM | 1 |
| Alfthan, G; Aro, A; Nissinen, K; Saarela, J; Tapani, K | 1 |
| Kelly, TL; Neaga, OR; Rozen, R; Schwahn, BC; Trasler, JM | 1 |
| Blom, HJ; den Heijer, M; Holm, PI; Keijzer, MB; Midttun, Ø; Ueland, PM; Vollset, SE | 1 |
| Johnson, DA; Kirk, JM; Minns, RA; Sandercock, PA; Tallur, KK | 1 |
| Fowler, B; Gutsche, S; Hennermann, JB; Horneff, G; Kozich, V; Mueller, P; Novotna, Z; Suormala, T; Vilarinho, L; Vilaseca, MA; Wilichowski, E; Zavadáková, P; Zeman, J | 1 |
| Olthof, MR; Verhoef, P | 1 |
| Borderie, D; Deschênes, G; Favier, R; Frémeaux-Bacchi, V; Giraudier, S; Guigonis, V; Massy, Z; Mougenot, B; Rosenblatt, DS | 1 |
| Boxer, AL; Finley, R; Goldman, J; Johnston, K; Kramer, JH; Miller, BL | 1 |
| Katan, MB; Olthof, MR; van Vliet, T; Verhoef, P; Zock, PL | 1 |
| Clarke, R; Holm, PI; Melse-Boonstra, A; Olthof, M; Ueland, PM; Verhoef, P | 1 |
| Fokkema, MR; Holm, PI; Muskiet, FA; Ueland, PM; van der Dijs, FP; Velzing-Aarts, FV | 1 |
| Choi, SW; Mason, JB | 1 |
| Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM | 1 |
| Lane, JB; Percy, AK | 1 |
| Bodamer, OA; Fowler, B; Huemer, M; Sass, JO; Simma, B; Suormala, T | 1 |
| Alscher, DM; Benzinger, P | 1 |
| Heyrovský, M; Kohlíková, E; Navrátil, T; Pelclová, D; Petr, M; Pristoupil, TI; Pristoupilová, K; Senholdová, Z | 1 |
| Gulevich, RG; Latypov, IF; Os'kina, IN; Pliusnina, IZ; Prasolova, LA; Trut, LN; Vsevolodov, EB | 1 |
| Cho, E; Colditz, GA; Dougherty, L; Jacques, P; Selhub, J; Willett, WC; Zeisel, SH | 1 |
| Nakajima, K | 1 |
| Dolinoy, DC; Lin, JR; Shi, X; Smith, CA; Tahiliani, KG; Waterland, RA | 1 |
| Boynton, A; Gregory, JF; James, SJ; Neuhouser, ML; Nijhout, HF; Reed, MC; Shane, B; Ulrich, CM | 1 |
| Benjamin, J; Gossell-Williams, M | 1 |
| Allen, RH; Goodfellow, J; Lang, D; Lewis, MJ; Madhavan, A; McDowell, IF; Moat, SJ; Payne, N; Stabler, SP; Taylor, SY | 1 |
| Austin, RC; Colgan, SM | 1 |
| Grotmol, T; Holm, PI; Hustad, S; Schneede, J; Ueland, PM; Vollset, SE | 1 |
| Bots, ML; Dalmeijer, GW; Olthof, MR; van der Schouw, YT; Verhoef, P | 1 |
| Benevenga, NJ | 1 |
| Blom, HJ; Clarke, R; de Groot, LC; Eussen, SJ; Hoefnagels, WH; Ueland, PM; van Staveren, WA | 1 |
| Abratte, CM; Caudill, MA; Li, R; Moriarty, DJ; Wang, W | 1 |
| Abdelmalek, MF; Barve, S; Benevenga, NJ; Halsted, CH; Kaplowitz, N; Kharbanda, KK; Liu, QY; Lu, SC; McClain, CJ; Purohit, V; Swanson, C; Zakhari, S | 1 |
| Lim, U; Ziegler, RG | 1 |
| Chiuve, SE; Dougherty, LW; Giovannucci, EL; Hankinson, SE; Rimm, EB; Willett, WC; Zeisel, SH | 1 |
| Bonham, MP; Clarkson, TW; Davidson, PW; Duffy, EM; McNulty, H; Molloy, AM; Myers, GJ; Robson, PJ; Scott, JM; Shamlaye, CF; Strain, J; Ueland, PM; Wallace, JM; Ward, M | 1 |
| Deng, L; Knock, E; Lawrance, AK; Rozen, R; Wang, XL; Wu, Q | 1 |
| Abratte, CM; Axume, J; Caudill, MA; Li, R; Moriarty, DJ; Wang, W | 1 |
| Abratte, CM; Caudill, MA; Hung, J; Li, R; Moriarty, DJ; Wang, W | 1 |
| Drevon, CA; Konstantinova, SV; Tell, GS; Ueland, PM; Ulvik, A; Vollset, SE | 1 |
| Barrish, JO; Glaze, DG; Isaacs, JS; Lane, JB; Motil, KJ; Neul, JL; O'Brien, WE; Percy, AK; Schultz, RJ; Smith, EO | 1 |
| Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M; Slow, S | 1 |
| Os'kina, IN; Pliusnina, IZ; Prasolova, LA; Trut, LN | 1 |
| Davidson, MH | 1 |
| Cho, E; Hankinson, SE; Holmes, MD; Willett, WC | 1 |
| Beckman, KB; Cropley, JE; Martin, DI; Suter, CM | 1 |
| Cho, E; Dougherty, L; Giovannucci, E; Jacques, PF; Lee, JE; Selhub, J; Zeisel, SH | 1 |
| Anselm, I; Bacino, CA; Barbieri-Welge, R; Beaudet, AL; Bichell, TJ; Bird, LM; Glaze, DG; Kimonis, V; Nespeca, M; O'Brien, WE; Peters, SU; Sanborn, E; Shinawi, LM; Sun, Q; Waisbren, S | 1 |
| Cooney, CA; Downing, C; Johnson, TE; Larson, C; Leakey, TI; Rafferty, TM; Siegfried, RN | 1 |
| Caudill, MA; Christensen, KE; Deng, L; Rozen, R; Wang, X; Wu, Q | 1 |
| Green, AC; Hayward, N; Hughes, MC; Ibiebele, TI; Montgomery, G; Pandeya, N; Webb, PM; Whiteman, DC; Zhao, Z | 1 |
| Dowd, SE; Harris, RA; Kellermayer, R; Schaible, TD; Smith, CW | 1 |
| Campion, J; Cordero, P; Martínez, JA; Milagro, FI | 2 |
| Alachkar, A; Lajin, B; Sakur, AA | 1 |
| Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M | 1 |
| Cheng, S; Feng, J; Wang, X | 1 |
| Boyd, RN; Davies, PS; Moxon-Lester, L; Obeid, R; Schoendorfer, NC; Sharp, N; Vitetta, L | 1 |
| Baccarelli, A; Boeke, CE; Burris, HH; Gillman, M; Kleinman, KP; Litonjua, AA; Rifas-Shiman, SL; Tarantini, L | 1 |
| Gillman, MW; Oken, E; Rifas-Shiman, SL; Villamor, E | 1 |
| Liu, Y; Liu, YQ; Morita, T; Sugiyama, K | 1 |
| Artuch, R; Montoya, J; Ormazabal, A; Pérez-Dueñas, B; Serrano, M | 1 |
| Barto, R; Blom, HJ; Imbard, A; Jakobs, C; Kok, RM; Smith, DE; Smulders, YM | 1 |
| Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
| Chen, YM; Ho, SC; Li, B; Lin, FY; Mo, XF; Pan, MX; Wang, L; Zhang, CX | 1 |
| Idris, S; McIlwee, A; Ukachukwu, V | 1 |
| Bertolo, RF; McBreairty, LE | 2 |
| Billington, CJ; Georgieff, MK; Gopalakrishnan, R; Hodges, JS; Petryk, A; Schmidt, B; Schotta, G; Zhang, L | 1 |
| Forman, MR; Hernandez, LM; Lupo, PJ; Peterson, CB; Shete, S; Spitz, MR; Swartz, MD; Vannucci, M; Wu, X | 1 |
| Boeke, CE; Gillman, MW; Hughes, MD; Oken, E; Rifas-Shiman, SL; Villamor, E | 1 |
| Delaney, C; Hewagama, A; Hoeltzel, MF; Johnson, K; Mickelson, B; Richardson, BC; Sawalha, AH; Strickland, FM; Wu, A; Yung, R | 1 |
| Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH | 1 |
| Ballesteros, M; Berrocal-Zaragoza, MI; Cavallé-Busquets, P; Fernandez-Ballart, JD; Fernàndez-Roig, S; Murphy, MM; Salat-Batlle, J; Ueland, PM | 1 |
| Collin, SM | 1 |
| Aiello, C; Boenzi, S; Cogo, P; Di Chiara, L; Dionisi-Vici, C; Iodice, FG; Monti, L | 1 |
| Dyer, RA; Innis, SM; King, DJ; Mulder, KA; Wu, BT | 1 |
| Obeid, R | 1 |
| Brust, TF; Lee, HJ; Lee, SC; Park, J; Watts, VJ; Yeo, Y | 1 |
| Bertoia, ML; Cooke, JP; Joosten, MM; Mittleman, MA; Mukamal, KJ; Pai, JK; Rimm, EB | 1 |
| Doperé, I; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Vansant, G | 2 |
| Bearden, D; D'Aco, KE; Ficicioglu, C; Hyland, K; Rosenblatt, DS; Watkins, D | 1 |
| Brody, LC; Fan, R; Kirke, PN; Liu, A; Mills, JL; Molloy, AM; Shane, B; Ueland, PM; Wang, Y | 1 |
| Ashapkin, VV; Fedotova, IB; Merzalov, IB; Pavlova, GV; Perepelkina, OV; Poletaeva, II; Surina, NM | 1 |
| Hamill, LL; Keaveney, EM; McNulty, H; Molloy, AM; Piironen, V; Price, RK; Shewry, PR; Strain, JJ; Ueland, PM; von Reding, W; Wallace, JM; Ward, JL; Ward, M; Welch, RW | 1 |
| Baumgartner, MR; Burda, P; Chinnery, PF; Demirkol, M; Dionisi-Vici, C; Dobbelaere, D; Fowler, B; Froese, DS; Gökcay, G; Häberle, J; Huemer, M; Lossos, A; Mengel, E; Morris, AA; Mulder-Bleile, R; Niezen-Koning, KE; Parini, R; Plecko, B; Rokicki, D; Schiff, M; Schimmel, M; Sewell, AC; Sperl, W; Spiekerkoetter, U; Steinmann, B; Suormala, T; Taddeucci, G; Trefz, F; Trejo-Gabriel-Galán, JM; Tsuji, M; Vilaseca, MA; von Kleist-Retzow, JC; Walker, V; Zeev, BB; Zeman, J | 1 |
| Berge, RK; Bjørndal, B; Lysne, V; Nordrehaug, JE; Nygård, O; Skorve, J; Vik, R | 1 |
| Coathup, V; Smith, L; Wheeler, S | 1 |
| Bertolo, RF; Brunton, JA; Harding, SV; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Cavallé-Busquets, P; Fernandez-Ballart, JD; Murphy, MM; Solé-Navais, P | 1 |
| Du, YF; Lin, FY; Long, WQ; Luo, WP; Mo, XF; Xu, M; Yan, B; Zhang, CX | 1 |
| Caudill, MA; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Malysheva, O; Parvez, F; Shahriar, H; Siddique, AB; Uddin, MN | 1 |
| Bertolo, RF; Robinson, JL | 1 |
| Carrier, B; Caudill, MA; Chuang, JC; Cohen, VV; Fomin, VG; Ganti, A; Ganz, AB; Lopez, YS; Lovesky, J; Malysheva, OV; Mohan, S; Mudrak, E; Shields, K; Stover, JA; Swersky, CC; Taeswuan, S; Vitiello, GA; Yan, J | 1 |
| Gylling, B; Häggström, J; Hallmans, G; Hultdin, J; Johansson, I; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Van Guelpen, B | 1 |
| Devlieger, R; Duca, RC; Freson, K; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Straetmans, D; Van Herck, E | 1 |
| Bartlett, RK; Bertolo, RF; Brunton, JA; Harding, SV; Randell, EW; Robinson, JL | 1 |
| Bertolo, RF; Brunton, JA; Harding, SV; Robinson, JL | 1 |
| Aris, IM; Chong, MF; Chong, YS; Fortier, MV; Gluckman, PD; Godfrey, KM; Kramer, MS; Lee, YS; Quah, PL; Saw, SM; Tint, MT; van Lee, L; Yap, FK | 1 |
| A S Langie, S; Bekaert, B; Devlieger, R; Duca, RC; Freson, K; Ghosh, M; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S | 1 |
| Kanbak, G; Kartkaya, K; Oglakci, A; Sogut, I; Uysal, O; Yucel, F | 1 |
| Bekaert, B; Devlieger, R; Duca, RC; Freson, K; Ghosh, M; Godderis, L; Huybrechts, I; Koppen, G; Langie, SAS; Pauwels, S | 1 |
| Bekaert, B; Devlieger, R; Duca, RC; Freson, K; Ghosh, M; Godderis, L; Huybrechts, I; Koppen, G; Langie, SAS; Pauwels, S; Truijen, I | 1 |
| Liu, J; Liu, X; Meng, Q; Peng, Y; Xu, H; Zhao, S; Zhou, N | 1 |
| Du, YF; Huang, J; Huang, WQ; Luo, WP; Mo, XF; Xu, M; Yan, B; Zhang, CX | 1 |
| Wu, MM; Yang, F | 1 |
| Che, L; Chen, Y; Fang, Z; Feng, B; Li, J; Lin, Y; Liu, H; Mou, D; Wang, J; Xu, S | 1 |
| Kang, SS; Rosenson, RS | 1 |
| Gylling, B; Häggström, J; Hallmans, G; Johansson, I; Midttun, Ø; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Ulvik, A; Van Guelpen, B | 1 |
| Barzilay, E; Berger, H; Caudill, MA; Croxford, R; Kim, YI; Ly, A; Malysheva, O; Masih, SP; Moon, A; O'Connor, DL; Plumptre, L; Sohn, KJ; Visentin, CE | 1 |
| Bartlett, RK; Bertolo, RF; Brunton, JA; Harding, SV; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Barlik, M; Chmurzynska, A; Drews, K; Jagodziński, PP; Kurzawińska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Szwengiel, A | 1 |
| Che, L; Fang, Z; Feng, B; Jiang, X; Jin, C; Li, J; Lin, Y; Xu, S; Xuan, Y; Zhao, Y; Zhou, P | 1 |
| Dahdoul, T; Nijhout, HF; Reed, MC; Sadre-Marandi, F | 1 |
| Ali, MA; Bakir, MB; Kamel, MA; Khalifa, EA; Refaat, R; Salama, MA | 1 |
| Bassett, JK; Boussioutas, A; Brinkman, MT; Dugué, PA; English, DR; Giles, GG; Hodge, AM; Joo, JE; Milne, RL; Mitchell, H; Southey, MC; Wong, EM | 1 |
| Crider, KS; Mitchell, AA; Parker, SE; Petersen, JM; Tinker, SC; Werler, MM | 1 |
| Bustamante, A; Cakora, P; Felder, MR; Hall-South, A; Owen, A; Shorter, KR; Smith, N; Vrana, PB; Yadon, N | 1 |
| Behrman, EJ; Krzycki, JA; Picking, JW; Zhang, L | 1 |
| Akemokwe, FM; Ceesay, K; James, PT; Jawla, O; Mohammed, NI; Prentice, AM; Silver, MJ; Sise, EA; Sonko, B | 1 |
| DiNicolantonio, JJ; McCarty, MF; O'Keefe, JH | 1 |
| Chu, KY; Huang, KT; Huang, RS; Ku, WC; Lee, CN; Liu, CY; Shen, YL | 1 |
| Anselm, I; Bacino, CA; Bichell, TJ; Bird, LM; Golden, S; Han, J; Kimonis, V; Peters, SU; Waisbren, S | 1 |
| Chmurzynska, A; Martínez, JA; Milagro, FI; Muzsik, A; Radziejewska, A | 1 |
| Chen, L; Du, HS; Guo, G; Huo, WJ; Liu, C; Liu, Q; Pei, CX; Wang, C; Wu, ZZ; Zhang, GW; Zhang, J; Zhang, SL | 1 |
| Florindo, C; Macário, MC; Tavares de Almeida, I; Vieira, D | 1 |
| Ampong, I; Eid, N; Griffiths, HR; Morgan, HL; Rouillon, C; Watkins, AJ | 1 |
| Bergamini, C; Capelli, I; Cappuccilli, M; Cianciolo, G; Conte, D; Donati, G; Giacomelli, FA; La Manna, G; Natali, T | 1 |
| Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Slavkovich, V; Uddin, MN | 1 |
| Elango, R | 1 |
| Jiang, H; Maclean, KN; Mclagan, BM; Phinney, WN; Roede, JR; Stabler, SP | 1 |
| Fishchuk, L; Gorovenko, N; Medvedieva, N; Rossokha, Z; Sheyko, L | 1 |
| Andraos, S; Cameron-Smith, D; Chia, PHP; D'Souza, RF; Gillies, NA; Knowles, SO; Milan, AM; Mitchell, CJ; Mitchell, SM; Ramzan, F; Roy, NC; Sharma, P; Sjödin, A; Wagner, KH; Zeng, N | 1 |
| Agudo, A; Ardanaz, E; Bakker, MF; Biessy, C; Casagrande, C; Chiodini, P; Chirlaque López, MD; Clasen, J; De Bacquer, D; Ericson, U; Ferrari, P; Fortner, RT; Godderis, L; Gunter, MJ; Gylling, B; Halkjær, J; Heath, AK; Huybrechts, I; Karlsson, T; Katzke, V; Manjer, J; Masala, G; Muller, D; Nicolas, G; Overvad, K; Pala, V; Papadimitriou, N; Sacerdote, C; Sánchez, MJ; Schmidt, JA; Schulze, MB; Tjønneland, A; Tumino, R; Van Herck, K; Van Puyvelde, H; Weiderpass, E | 1 |
| Devlieger, R; Godderis, L; Hoeylaerts, S; Huybrechts, I; Koppen, G; Pauwels, S; Van Opstal, A | 1 |
| Chang, CY; Chang, TY; Doong, JY; Huang, RS; Kuo, CS; Lee, FJ; Lin, YS; Wang, BW; Wu, CH | 1 |
| Cruz, M; Diaz-Flores, M; Fernandez-Osornio, LF; Gomez-Diaz, RA; Gonzalez-Carranza, E; Hernández-Pineda, J; Maldonado-Rodriguez, R; Mondragon-Gonzalez, R; Sharma, T; Valladares-Salgado, A; Wacher, NH | 1 |
| Chmurzynska, A; Muzsik-Kazimierska, A; Nikrandt, G; Szwengiel, A | 1 |
| Broz, P; Racek, J; Rajdl, D; Stehlík, P; Trefil, L | 1 |
| Fishchuk, L; Gorovenko, N; Rossokha, Z; Yeroshkina, K | 1 |
| Arthurs, AL; Jankovic-Karasoulos, T; Roberts, CT; Smith, MD; Williamson, JM | 1 |
| Chen, S; Fang, AP; He, TT; Huang, BX; Huang, RZ; Huang, ZH; Li, SY; Liu, XZ; Liu, ZY; Lu, XT; Luo, Y; Maierhaba, W; Mo, QW; Wang, YF; Wang, YN; Yang, MT; Zhang, XG; Zhu, HL | 1 |
| Guyader, J; Jiang, Q; Loor, JJ; Pan, YX; Sherlock, DN; Zhang, H | 1 |
| Fukuoka, H; Horiguchi, S; Kagawa, Y; Kawabata, T; Kubo, Y; Nishikawa, M; Shoji, K; Tajima, A | 1 |
| Alegria-Lertxundi, I; Arroyo-Izaga, M; de Pancorbo, MM; Martín-Fernández-de-Labastida, S | 1 |
| Feiten, AF; Ittner, LM; Ke, YD; Sontag, E; Sontag, JM; Taleski, G; van Hummel, A | 1 |
| Carmichael, SL; Darling, AM; Desrosiers, TA; Nestoridi, E; Parker, SE; Petersen, JM; Politis, MD; Shaw, GM; Smith-Webb, RS; Werler, MM; Yazdy, MM | 1 |
23 review(s) available for betaine and folic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Aged; Animals; Betaine; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Methylmalonyl-CoA Mutase; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Hyperhomocysteinaemia: a newly recognized risk factor for vascular disease.
Topics: Arteriosclerosis; Betaine; Coronary Disease; Folic Acid; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Methionine; Pyridoxine; Risk Factors; Vascular Diseases | 1994 |
Remethylation defects: guidelines for clinical diagnosis and treatment.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12 | 1998 |
Effects of betaine intake on plasma homocysteine concentrations and consequences for health.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Folic Acid; Homocysteine; Humans; Lipids | 2005 |
Effects of alcohol on folate metabolism: implications for carcinogenesis.
Topics: Animals; Betaine; Biological Availability; Central Nervous System Depressants; Choline; Ethanol; Folic Acid; Humans; Neoplasms | 2005 |
Rett syndrome: model of neurodevelopmental disorders.
Topics: Betaine; Female; Folic Acid; Gallbladder Diseases; Gastrointestinal Agents; Hematinics; Humans; Infant; Methyl-CpG-Binding Protein 2; Rett Syndrome | 2005 |
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium.
Topics: Animals; Betaine; Disease Models, Animal; Folic Acid; Humans; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine | 2007 |
[Research advances in the treatment of hyperhomocysteinemia].
Topics: Animals; Betaine; Folic Acid; Genetic Therapy; Humans; Hyperhomocysteinemia; Taurine | 2011 |
Genetic causes of cerebral folate deficiency: clinical, biochemical and therapeutic aspects.
Topics: Betaine; Cerebral Cortex; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Humans; Intestinal Absorption; Leucovorin; Nervous System Diseases; Tetrahydrofolates | 2012 |
The nutritional burden of methylation reactions.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Creatine; Diet; Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nutritional Status; Phosphatidylcholines | 2013 |
Folate and B12 in prostate cancer.
Topics: Betaine; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Male; Meta-Analysis as Topic; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Vitamin B 12 | 2013 |
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine | 2013 |
Early pregnancy B vitamin status, one carbon metabolism, pregnancy outcome and child development.
Topics: Betaine; Carbon; Child; Child Development; Child, Preschool; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Trimester, Third; Sarcosine; Vitamin B 12 | 2016 |
The dynamics of methionine supply and demand during early development.
Topics: Betaine; Child Development; Choline; Creatine; Diet; Dietary Supplements; DNA Methylation; Folic Acid; Humans; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Methionine; Phosphatidylcholines | 2016 |
The Pediatric Methionine Requirement Should Incorporate Remethylation Potential and Transmethylation Demands.
Topics: Amino Acids; Betaine; Diet; DNA Methylation; Folic Acid; Humans; Methionine; Methylation; Neonatology; Nutritional Requirements; Phosphatidylcholines; Protein Biosynthesis | 2016 |
[Research advances in the association between maternal intake of methyl donor nutrients during pregnancy and DNA methylation in offspring].
Topics: Betaine; Choline; DNA Methylation; Female; Folic Acid; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Vitamin B 12 | 2017 |
Analytic Approaches for the Treatment of Hyperhomocysteinemia and Its Impact on Vascular Disease.
Topics: Animals; Betaine; Biomarkers; Cardiovascular Diseases; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Phenotype; Risk Factors; Tetrahydrofolates; Treatment Outcome | 2018 |
One-Carbon Metabolism and Nonalcoholic Fatty Liver Disease: The Crosstalk between Nutrients, Microbiota, and Genetics.
Topics: Animals; Betaine; Carbon; Choline; Disease Progression; Female; Folic Acid; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lipid Metabolism; Liver; Methionine; Microbiota; Models, Genetic; Non-alcoholic Fatty Liver Disease; Nutrients; Polymorphism, Single Nucleotide; Pregnancy; Prenatal Exposure Delayed Effects; Risk | 2020 |
Vitamin B Supplementation and Nutritional Intake of Methyl Donors in Patients with Chronic Kidney Disease: A Critical Review of the Impact on Epigenetic Machinery.
Topics: Betaine; Cardiovascular Diseases; Choline; Dietary Supplements; DNA Methylation; Eating; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methionine; Nutritional Physiological Phenomena; Renal Insufficiency, Chronic; Uremia; Vitamin B 12; Vitamin B 6 | 2020 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
Betaine consumption as a new clinical approach to treatment and prophylaxis of folate-related pathologies.
Topics: Amino Acids; Betaine; Betaine-Homocysteine S-Methyltransferase; Folic Acid; Homocysteine; Humans; Methionine | 2023 |
High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Neural Tube Defects; Pregnancy; Thymidylate Synthase; Vitamin B 12 | 2022 |
24 trial(s) available for betaine and folic acid
| Article | Year |
|---|---|
No change in impaired endothelial function after long-term folic acid therapy of hyperhomocysteinaemia in haemodialysis patients.
Topics: Adult; Aged; Betaine; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Renal Dialysis | 1998 |
Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients.
Topics: Adult; Betaine; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Time Factors; Treatment Outcome | 1999 |
Vascular outcome in patients with homocystinuria due to cystathionine beta-synthase deficiency treated chronically: a multicenter observational study.
Topics: Adolescent; Adult; Aged; Betaine; Cardiovascular Diseases; Child; Child, Preschool; Comorbidity; Drug Therapy, Combination; Folic Acid; Follow-Up Studies; Homocystinuria; Humans; Middle Aged; Pyridoxine; Risk Assessment | 2001 |
Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure.
Topics: Aged; Betaine; Cross-Over Studies; Drug Therapy, Combination; Fasting; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipids; Male; Methionine; Middle Aged; Pyridoxine; Sarcosine | 2002 |
Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects.
Topics: Adult; Betaine; Blood Pressure; Body Composition; Body Weight; Diet; Dietary Supplements; Energy Intake; Energy Metabolism; Female; Folic Acid; Homocystine; Humans; Lipoproteins; Lipotropic Agents; Male; Middle Aged; Physical Exertion | 2002 |
Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Betaine; Choline; Coronary Angiography; Dietary Supplements; Drug Administration Schedule; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Methyltransferases; Middle Aged; Sarcosine; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2004 |
Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans.
Topics: Adult; Aged; Betaine; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Lipids; Lipotropic Agents; Male; Middle Aged; Phosphatidylcholines; Placebos; Risk Factors | 2005 |
Betaine concentration as a determinant of fasting total homocysteine concentrations and the effect of folic acid supplementation on betaine concentrations.
Topics: Administration, Oral; Aged; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged | 2005 |
High- but not low-dose folic acid improves endothelial function in coronary artery disease.
Topics: Aged; Betaine; Cardiotonic Agents; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Female; Folic Acid; Hematinics; Humans; Male; Middle Aged | 2006 |
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.
Topics: Aged; Attention; Betaine; Choline; Cognition; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Neuropsychological Tests; Psychomotor Performance; Sarcosine; Vitamin B 12; Vitamin B Complex | 2007 |
Choline status is not a reliable indicator of moderate changes in dietary choline consumption in premenopausal women.
Topics: Adolescent; Adult; Betaine; Choline; Diet; Female; Folic Acid; Genotype; Humans; Liver Diseases; Nutritional Status; Phosphatidylcholines; Premenopause; Sphingomyelins; Treatment Outcome | 2009 |
A study of the treatment of Rett syndrome with folate and betaine.
Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Double-Blind Method; Female; Folic Acid; Humans; Infant; Methyl-CpG-Binding Protein 2; Rett Syndrome; Treatment Outcome; Young Adult | 2009 |
Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males.
Topics: Adult; Betaine; Biomarkers; Choline; Creatinine; Cross-Over Studies; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Lipids; Male; Sarcosine; Time Factors; Vitamin B 12; Young Adult | 2009 |
Double-blind therapeutic trial in Angelman syndrome using betaine and folic acid.
Topics: Adolescent; Angelman Syndrome; Betaine; Child; Child, Preschool; Chromosomes, Human, Pair 15; DNA Methylation; Double-Blind Method; Drug Combinations; Female; Folic Acid; Genomic Imprinting; Humans; Infant; Lipotropic Agents; Male; Phenotype; Placebos; Ubiquitin-Protein Ligases; Vitamin B Complex | 2010 |
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Northern Ireland; Nutritional Status; Patient Compliance; Postmenopause | 2012 |
Postprandial plasma betaine and other methyl donor-related responses after consumption of minimally processed wheat bran or wheat aleurone, or wheat aleurone incorporated into bread.
Topics: Adult; Betaine; Bread; Choline; Cross-Over Studies; Dietary Fiber; Female; Folic Acid; Food Handling; Humans; Male; Postprandial Period; Sarcosine; Seeds; Triticum | 2015 |
Supplementation with Folic Acid, but Not Creatine, Increases Plasma Betaine, Decreases Plasma Dimethylglycine, and Prevents a Decrease in Plasma Choline in Arsenic-Exposed Bangladeshi Adults.
Topics: Adult; Arsenic; Bangladesh; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Female; Folic Acid; Humans; Male; Middle Aged; Sarcosine; Tandem Mass Spectrometry; Vitamin B Complex; Young Adult | 2016 |
Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis.
Topics: Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Genotype; Humans; Lactation; Methylenetetrahydrofolate Reductase (NADPH2); Phosphatidylcholines; Polymorphism, Single Nucleotide | 2016 |
Maternal methyl donor supplementation during gestation counteracts bisphenol A-induced oxidative stress in sows and offspring.
Topics: Actins; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Benzhydryl Compounds; Betaine; Catalase; Choline; Diet; Dietary Supplements; Female; Folic Acid; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Malondialdehyde; Maternal Nutritional Physiological Phenomena; Oxidative Stress; Phenols; Placenta; Pregnancy; Superoxide Dismutase; Swine; Vitamin B 12 | 2018 |
A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia.
Topics: Adolescent; Adult; Betaine; Dietary Supplements; Female; Folic Acid; Gambia; Homocysteine; Humans; Middle Aged; Nutritional Status; Riboflavin; Vitamin B 12; Young Adult | 2019 |
A placebo-controlled trial of folic acid and betaine in identical twins with Angelman syndrome.
Topics: Angelman Syndrome; Betaine; Child; Double-Blind Method; Folic Acid; Gastrointestinal Agents; Humans; Male; Sequence Deletion; Twins, Monozygotic; Vitamin B Complex | 2019 |
Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults.
Topics: Adult; Arsenic; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Folic Acid; Homocysteine; Humans; Methylation | 2021 |
Responsiveness of one-carbon metabolites to a high-protein diet in older men: Results from a 10-wk randomized controlled trial.
Topics: Aged; Betaine; Carbon; Choline; Diet; Diet, High-Protein; Folic Acid; Homocysteine; Humans; Male; Vitamin B Complex | 2021 |
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial.
Topics: Adolescent; Adult; Aged; Betaine; Dietary Supplements; Double-Blind Method; East Asian People; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 12; Vitamin B Complex; Young Adult | 2023 |
159 other study(ies) available for betaine and folic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes.
Topics: Animals; Betaine; Carcinogens; Carcinoma, Hepatocellular; Choline; Diet; Ethanolamines; Folic Acid; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methotrexate; Neoplasms, Experimental; Nitrosamines; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Vitamin B 12 | 1975 |
Plasmodium knowlesi: in vitro biosynthesis of methionine and thymidylic acid.
Topics: Animals; Betaine; Cells, Cultured; Choline; Erythrocytes; Folic Acid; Formaldehyde; Formyltetrahydrofolates; Haplorhini; Histidine; Homocysteine; Macaca mulatta; Methionine; Plasmodium; Sarcosine; Serine; Thymidine Monophosphate; Thymine Nucleotides | 1977 |
Effects of long chain fatty acids on solute absorption: perfusion studies in the human jejunum.
Topics: Betaine; Bile Acids and Salts; Biological Transport; Fatty Acids, Unsaturated; Folic Acid; Glucose; Glycerides; Humans; Jejunum; Leucine; Mannitol; Oleic Acids; Perfusion; Ricinoleic Acids; Water-Electrolyte Balance; Xylose | 1977 |
Methionine toxicity in chicks and poults.
Topics: Animals; Betaine; Bone Diseases, Developmental; Chickens; Folic Acid; Glycine; Homocystine; Male; Methionine; Paralysis; Poultry Diseases; Turkeys | 1978 |
Homocysteinemia: depressed plasma serine levels.
Topics: Adult; Betaine; Carbon-Oxygen Lyases; Child, Preschool; Folic Acid; Glycine; Homocysteine; Humans; Isoleucine; Kidney Transplantation; Lyases; Male; Serine | 1987 |
Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients.
Topics: Adolescent; Adult; Betaine; Child; Cystathionine beta-Synthase; Cysteine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Male; Methionine; Middle Aged; Pyridoxine; Serine | 1985 |
Ethanol, the choline requirement, methylation and liver injury.
Topics: Animals; Betaine; Choline; Ethanol; Folic Acid; Homocysteine; Liver; Methionine; Methylation; Rats; Tetrahydrofolates | 1985 |
Folate deficiency and formiminoglutamic acid excretion during chronic diethylnitrosamine administration to rats.
Topics: Animals; Betaine; Carcinogens; Choline; Diet; Drinking; FIGLU Test; Folic Acid; Folic Acid Deficiency; Glutamates; Histidine; Liver; Male; Methionine; Nitrosamines; Rats; Stimulation, Chemical; Transferases; Urocanate Hydratase; Vitamin B 12 | 1973 |
A study of the behavioral disruption of mice induced by l-methionine and related compounds.
Topics: Amphetamine; Animals; Behavior, Animal; Betaine; Chlorpromazine; Cystathionine; Folic Acid; Histidine; Homocysteine; Homoserine; Male; Mescaline; Methionine; Mice; N,N-Dimethyltryptamine; Niacinamide; Serine; Social Behavior | 1974 |
[Importance and regulation of the cobalamin-dependent methionine synthetase and the betaine: homocystein methyltransferase in methionine and tetrahydrofolic acid metabolism of the rat].
Topics: Animals; Betaine; Coenzyme A; Diet; Female; Folic Acid; Homocysteine; Kidney; Liver; Methionine; Methylation; Methyltransferases; Rats; Tetrahydrofolates; Vitamin B 12 | 1973 |
The effect of methionine on folic acid and histidine metabolism in perfused rat liver.
Topics: Animals; Betaine; Carbon Dioxide; Carbon Isotopes; Choline; Deficiency Diseases; Drug Synergism; Ethionine; Folic Acid; Formates; Glutamates; Histidine; Homocysteine; Liver; Male; Methionine; Oxidation-Reduction; Peptides; Perfusion; Rats; Tetrahydrofolates; Vitamin B 12 Deficiency | 1972 |
Relationship of arginine and methionine to creatine formation in chicks.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Body Weight; Chickens; Choline; Choline Deficiency; Creatine; Cystine; Deficiency Diseases; Depression, Chemical; Folic Acid; Folic Acid Deficiency; Glycine; Glycine max; Guanidines; Lipid Metabolism; Liver; Male; Methionine; Muscles; Ornithine; Stimulation, Chemical; Urea; Vitamin B 12; Vitamin B 12 Deficiency; Zea mays | 1971 |
Factors affecting formiminoglutamic acid excretion in vitamin B 12 deficiency.
Topics: Aminopterin; Animals; Betaine; Female; Folic Acid; Folic Acid Deficiency; Glutarates; Histidine; Male; Methionine; Rats; Sheep; Vitamin B 12; Vitamin B 12 Deficiency | 1970 |
Deranged B 12 metabolism: effects on sulfur amino acid metabolism.
Topics: Adenosine Triphosphate; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Betaine; Brain Chemistry; Carbon Isotopes; Child, Preschool; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Isomerases; Kidney; Liver; Male; Malonates; Methionine; Methyltransferases; Transferases; Vitamin B 12 | 1970 |
Dietary treatment of homocystinuria.
Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Child, Preschool; Diet Therapy; Female; Folic Acid; Growth; Homocystinuria; Humans; Infant; Infant, Newborn; Intellectual Disability; Intelligence Tests; Male; Quaternary Ammonium Compounds | 1967 |
Methotrexate hepatotoxicity.
Topics: Animals; Betaine; Cholesterol Esters; Folic Acid; Homocysteine; Lipotropic Agents; Liver; Male; Methionine; Methotrexate; Methylation; Rats; Tetrahydrofolates; Triglycerides | 1984 |
The use of betaine for the treatment of homocystinuria.
Topics: Administration, Oral; Adult; Betaine; Child; Female; Folic Acid; Homocystine; Homocystinuria; Humans; Male; Methionine; Pyridoxine | 1981 |
Short term betaine therapy fails to lower elevated fasting total plasma homocysteine concentrations in hemodialysis patients maintained on chronic folic acid supplementation.
Topics: Adult; Aged; Betaine; Fasting; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Treatment Failure | 1995 |
[Homocystinuria: effectiveness of the treatment with pyridoxine, folic acid, and betaine].
Topics: Betaine; Child; Child, Preschool; Drug Evaluation; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Male; Pyridoxine | 1993 |
Symptomatic and asymptomatic methylenetetrahydrofolate reductase deficiency in two adult brothers.
Topics: Adult; Betaine; Enzyme Stability; Folic Acid; Homocystine; Humans; Male; Metabolism, Inborn Errors; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Nervous System Diseases; Oxidoreductases Acting on CH-NH Group Donors; Paraparesis, Tropical Spastic | 1993 |
Treatment of hyperhomocyst(e)inemia: physiological basis.
Topics: Betaine; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 1996 |
Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency.
Topics: Animals; Apoptosis; Betaine; Cell Line; Choline Deficiency; Culture Media; Folic Acid; Liver; Male; Methylation; Rats; Rats, Inbred F344; Vitamin B 12 | 1997 |
Strategies for the treatment of cystathionine beta-synthase deficiency: the experience of the Willink Biochemical Genetics Unit over the past 30 years.
Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Female; Folic Acid; Gastrointestinal Agents; Genetic Testing; Homocysteine; Homocystinuria; Humans; Infant; Infant, Newborn; Male; Pregnancy; Pregnancy Complications; Pyridoxine; Treatment Failure; Treatment Outcome | 1998 |
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice.
Topics: 5-Methylcytosine; Agouti Signaling Protein; Animals; Betaine; Choline; Cytosine; Dietary Supplements; Female; Folic Acid; Gene Expression Regulation; Genomic Imprinting; Hair Color; Intercellular Signaling Peptides and Proteins; Male; Methionine; Mice; Mice, Inbred Strains; Pregnancy; Proteins; S-Adenosylmethionine; Vitamin B 12; Zinc | 1998 |
The molecular basis of cystathionine beta-synthase deficiency in Dutch patients with homocystinuria: effect of CBS genotype on biochemical and clinical phenotype and on response to treatment.
Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Cystathionine beta-Synthase; Female; Fibroblasts; Folic Acid; Genotype; Homocystinuria; Humans; Male; Middle Aged; Mutation; Netherlands; Phenotype; Pyridoxine | 1999 |
Methylenetetrahydrofolate reductase deficiency: importance of early diagnosis.
Topics: Betaine; Child, Preschool; Diagnosis, Differential; Fatal Outcome; Fibroblasts; Folic Acid; Hematinics; Homocysteine; Homocystinuria; Homozygote; Humans; Infant; Intellectual Disability; Lipotropic Agents; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Treatment Outcome | 2000 |
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Betaine; Betaine-Homocysteine S-Methyltransferase; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methyltransferases; Middle Aged; Peritoneal Dialysis; Predictive Value of Tests; Pyridoxine; Renal Dialysis; Sarcosine; Uremia; Vitamin B 12; Zinc | 2001 |
Classic homocystinuria: clinical, biochemical and radiological observations, and therapeutic outcome of 24 Saudi patients.
Topics: Betaine; Child; Child, Preschool; Combined Modality Therapy; Consanguinity; Drug Monitoring; Drug Therapy, Combination; Female; Folic Acid; Homocystinuria; Humans; Infant; Male; Methionine; Pedigree; Pyridoxine; Saudi Arabia; Treatment Outcome | 1999 |
Practical management of combined methylmalonicaciduria and homocystinuria.
Topics: Adolescent; Adult; Betaine; Carnitine; Child; Child, Preschool; Female; Folic Acid; Gastrointestinal Agents; Hematinics; Homocystinuria; Humans; Hydrocephalus; Hydroxocobalamin; Injections, Intramuscular; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Microcephaly; Seizures | 2002 |
Betaine supplementation lowers plasma homocysteine in healthy men and women.
Topics: Adult; Betaine; Blood Glucose; Blood Pressure; Body Mass Index; Diet; Dietary Supplements; Eating; Fasting; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Reference Values | 2003 |
Transposable elements: targets for early nutritional effects on epigenetic gene regulation.
Topics: Alleles; Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA Methylation; DNA Transposable Elements; Exons; Folic Acid; Gene Expression Regulation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Models, Genetic; Molecular Sequence Data; Nutritional Physiological Phenomena; Phenotype; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Vitamin B 12 | 2003 |
Effect of diet on betaine-homocysteine transmethylase of rat liver. III. B-vitamins other than vitamin B12.
Topics: Animals; Betaine; Diet; Enzymes; Folic Acid; Homocysteine S-Methyltransferase; Liver; Rats; Vitamin B 12; Vitamin B Complex; Vitamins | 1955 |
Vitamin B12 and folic acid in relation to methionine synthesis from betaine in vivo and invitro.
Topics: Betaine; Choline; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 1957 |
Antagonism of gamma-butyrobetaine and carnitine on chick embryonic bones cultivated in vitro.
Topics: Animals; Betaine; Bone and Bones; Carnitine; Chickens; Choline; Folic Acid; In Vitro Techniques; Vitamin B Complex | 1957 |
[Antagonism of gamma-butyrobetaine and carnitine in bone skeleton cultivated in vitro].
Topics: Betaine; Bone and Bones; Carnitine; Choline; Embryo, Mammalian; Embryo, Nonmammalian; Folic Acid; In Vitro Techniques; Vitamin B Complex | 1957 |
[The influence of gama-butyrobetaine, crotonic acid betaine and isomeric carnitine on the growth of a mouse sarcoma].
Topics: Animals; Betaine; Carnitine; Choline; Folic Acid; Sarcoma, Experimental; Vitamin B Complex | 1962 |
The isolation of gamma-butyrobetaine, crotonbetaine and carnitine from brains of animals killed during induced convulsions.
Topics: Alkaloids; Animals; Betaine; Brain; Carnitine; Folic Acid; Seizures; Vitamin B Complex | 1963 |
[Metabolism of carnitine and crotonic betaine in the chick embryo].
Topics: Amino Acids; Animals; Betaine; Carnitine; Chick Embryo; Croton; Folic Acid; Vitamin B Complex | 1963 |
[ON THE DETERMINATION OF CARNITINE AS CROTONIC ACID BETAINE].
Topics: Ammonium Compounds; Betaine; Carnitine; Croton Oil; Folic Acid; Photometry; Polarography; Quaternary Ammonium Compounds; Research; Vitamin B Complex | 1963 |
ACTIONS OF BETAINE, CARNITINE AND CHOLINE ON THE PATTERN OF HEPATIC LIPOSIS IN MICE FED A HIGH-FAT, LOW-PROTEIN DIET.
Topics: Animals; Betaine; Carnitine; Choline; Diet, High-Fat; Diet, Protein-Restricted; Dietary Fats; Dietary Proteins; Folic Acid; Lipid Metabolism; Lipidoses; Lipotropic Agents; Liver; Liver Diseases; Mice; Pathology; Research; Statistics as Topic; Vitamin B Complex | 1964 |
[ON THE ACETYLCHOLINE-LIKE EXCITATION LEVEL AND COENZYME A ESTER OF BETAINE IN THE BRAIN AND ON ENZYMATIC ACETYLCARNITINE HYDROLYSIS].
Topics: Acetylcarnitine; Acetylcholine; Acetylcholinesterase; Ammonium Compounds; Betaine; Brain; Brain Chemistry; Carnitine; Chromatography; Coenzyme A; Folic Acid; Hydrolysis; Quaternary Ammonium Compounds; Rats; Research; Vitamin B Complex | 1964 |
THE EFFECTS OF CHOLINE AND RELATED COMPOUNDS ON THE GROWTH AND DEVELOPMENT OF DROSOPHILA MELANOGASTER.
Topics: Amino Acids; Amino Alcohols; Ammonium Compounds; Animals; Betaine; Carnitine; Chemical Phenomena; Chemistry; Choline; Diet; Drosophila; Drosophila melanogaster; Fatty Liver; Folic Acid; Growth and Development; Meat; Metamorphosis, Biological; Methionine; Neurospora; Pharmacology; Poultry; Quaternary Ammonium Compounds; Rats; Research; Salts; Vitamin B Complex | 1965 |
The chick's requirement for folic acid in the utilization of choline and its precursors betaine and methylaminoethanol.
Topics: Animals; Betaine; Chickens; Choline; Folic Acid; Humans; Meat; Poultry | 1955 |
Studies on lipid metabolism in mice treated with beta-hydroxy, gamma-betaine-butyric acid.
Topics: Animals; Betaine; Butyrates; Butyric Acid; Folic Acid; Gamma Rays; Lipid Metabolism; Mice; Vitamin B Complex | 1962 |
The effect of low doses of betaine on plasma homocysteine in healthy volunteers.
Topics: Adult; Betaine; Dose-Response Relationship, Drug; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Lipotropic Agents; Male; Middle Aged | 2004 |
Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Animals; Betaine; Dietary Supplements; Drug Administration Schedule; Fertility; Fertility Agents, Male; Folic Acid; Germ Cells; Infertility, Male; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Knockout; Sperm Count; Spermatogenesis; Statistics, Nonparametric; Testis | 2005 |
Betaine and folate status as cooperative determinants of plasma homocysteine in humans.
Topics: Adult; Aged; Betaine; Choline; Creatinine; Dose-Response Relationship, Drug; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6 | 2005 |
Folate-induced reversal of leukoencephalopathy and intellectual decline in methylene-tetrahydrofolate reductase deficiency: variable response in siblings.
Topics: Activities of Daily Living; Adolescent; Adult; Betaine; Brain; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Homocystinuria; Humans; Intelligence; Leukoencephalopathy, Progressive Multifocal; Long-Term Care; Magnetic Resonance Imaging; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Neurologic Examination; Treatment Outcome | 2005 |
cblE type of homocystinuria due to methionine synthase reductase deficiency: functional correction by minigene expression.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Betaine; Brain; Cell Line, Transformed; Codon, Nonsense; DNA Mutational Analysis; Ferredoxin-NADP Reductase; Fibroblasts; Folic Acid; Genes, Synthetic; Genetic Complementation Test; Genetic Therapy; Haplotypes; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Mutation, Missense; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Recombinant Fusion Proteins; Sequence Deletion; Transfection; White People | 2005 |
Late-onset thrombocytic microangiopathy caused by cblC disease: association with a factor H mutation.
Topics: Anemia; Betaine; Child; Combined Modality Therapy; Complement Factor H; Drug Therapy, Combination; Endothelium, Vascular; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Haptoglobins; Hemolytic-Uremic Syndrome; Humans; Hydroxocobalamin; Hypertension; Kidney; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Nephrotic Syndrome; Plasma Exchange; Point Mutation; Proteinuria; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Renal Dialysis; Vitamin B 12 | 2005 |
Executive dysfunction in hyperhomocystinemia responds to homocysteine-lowering treatment.
Topics: Adult; Anticoagulants; Betaine; Cognition Disorders; Confusion; Disease Progression; Drug Therapy, Combination; Folic Acid; Frontal Lobe; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Remission Induction; Seizures; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2005 |
Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy.
Topics: Adult; Africa, Western; Betaine; Black People; Choline; Dietary Supplements; Female; Folic Acid; Gestational Age; Hematinics; Homocysteine; Humans; Netherlands Antilles; Nutritional Status; Postpartum Period; Predictive Value of Tests; Pregnancy; Regression Analysis | 2005 |
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12 | 2005 |
Prenatal and postnatal treatment in cobalamin C defect.
Topics: Betaine; Carnitine; Female; Folic Acid; Hematinics; Humans; Hydroxocobalamin; Infant, Newborn; Lipotropic Agents; Male; Metabolism, Inborn Errors; Pregnancy; Prenatal Care; Prenatal Diagnosis; Vitamin B 12 Deficiency | 2005 |
[Untreated homocystinuria in adulthood].
Topics: Adult; Age Factors; Angina Pectoris; Betaine; Diagnosis, Differential; Drug Therapy, Combination; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Intervertebral Disc Displacement; Lens Subluxation; Male; Marfan Syndrome; Myopia; Osteoporosis; Retinal Detachment; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2005 |
Diagnostic significance of urinary thiodiglycolic acid as a possible tool for studying the role of vitamins B12 and folates in the metabolism of thiolic substances.
Topics: Adult; Betaine; Biomarkers; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Leucovorin; Male; Sulfhydryl Compounds; Thioglycolates; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
[The effect of methyl-containing supplements during pregnancy on the phenotypic modification of offspring hair color in rats].
Topics: Agouti Signaling Protein; Animals; Betaine; Choline; Color; Dietary Supplements; Electron Spin Resonance Spectroscopy; Female; Folic Acid; Hair Color; Heterozygote; Homozygote; Intercellular Signaling Peptides and Proteins; Male; Methionine; Phenotype; Pigments, Biological; Pregnancy; Rats; Vitamin B 12; Zinc | 2006 |
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Betaine; Choline; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Sex Factors; Surveys and Questionnaires; Vitamin B Complex | 2006 |
Hyperhomocysteinemia can be ameliorated by dimethylsulfoniopropionate in place of folic acid in mice.
Topics: Animals; Betaine; Chromatography, High Pressure Liquid; Folic Acid; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Kinetics; Male; Mice; Mice, Inbred ICR; Sulfonium Compounds | 2006 |
Maternal methyl supplements increase offspring DNA methylation at Axin Fused.
Topics: Alleles; Animals; Axin Protein; Betaine; Body Weight; Choline; CpG Islands; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Gene Expression Regulation; Heterozygote; Introns; Mice; Mice, Inbred C57BL; Models, Genetic; Polymerase Chain Reaction; Pregnancy; Random Allocation; Repressor Proteins; Sulfites; Vitamin B 12 | 2006 |
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
Topics: Betaine; Carbon; DNA Methylation; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Kinetics; Mathematics; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Molecular Biology; Nutritional Physiological Phenomena; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polymorphism, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2006 |
Choline: are our university students eating enough?
Topics: Adult; Betaine; Choline Deficiency; Female; Folic Acid; Food Analysis; Humans; Jamaica; Male; Nutrition Assessment; Nutritional Status; Pilot Projects; Students, Medical; Universities | 2006 |
Homocysteinylation of metallothionein impairs intracellular redox homeostasis: the enemy within!
Topics: Atherosclerosis; Betaine; Endothelium, Vascular; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Metallothionein; Oxidation-Reduction; Risk Factors; Vitamin B Complex | 2007 |
Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->t genotypes and B-vitamin status in a large-scale epidemiological study.
Topics: Betaine; Choline; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins | 2007 |
Prospective study on dietary intakes of folate, betaine, and choline and cardiovascular disease risk in women.
Topics: Aged; Betaine; Cardiovascular Diseases; Choline; Cohort Studies; Diet; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Middle Aged; Netherlands; Nutrition Surveys; Odds Ratio; Postmenopause; Prospective Studies; Surveys and Questionnaires | 2008 |
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.
Topics: Betaine; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Neural Tube Defects; Nutritional Physiological Phenomena; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex | 2007 |
Folate intake and the MTHFR C677T genotype influence choline status in young Mexican American women.
Topics: Adolescent; Adult; Betaine; Choline; Diet; Dietary Supplements; Female; Folic Acid; Genotype; Hispanic or Latino; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Nutritional Status; Phosphatidylcholines; Sphingomyelins | 2008 |
One-carbon metabolism, colorectal carcinogenesis, chemoprevention--with caution.
Topics: Animals; Betaine; Carbon; Cell Transformation, Neoplastic; Chemoprevention; Choline; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine | 2007 |
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
Topics: Adult; Alcohol Drinking; Betaine; Biomarkers; Choline; Cross-Sectional Studies; Diet Records; Female; Folic Acid; Homocysteine; Humans; Linear Models; Lipotropic Agents; Methylation; Middle Aged; Predictive Value of Tests; Surveys and Questionnaires; Vitamin B Complex | 2007 |
Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study.
Topics: Adult; Betaine; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methionine; Parturition; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Third; Seychelles; Vitamin B 12; Vitamin B Complex | 2008 |
Strain differences in mice highlight the role of DNA damage in neoplasia induced by low dietary folate.
Topics: Animals; Betaine; Diet; DNA Damage; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Genotype; Homocysteine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; RNA, Messenger; Thymine Nucleotides; Uridine Triphosphate | 2008 |
Ethnicity and folate influence choline status in young women consuming controlled nutrient intakes.
Topics: Adolescent; Adult; Betaine; Black or African American; Body Mass Index; Choline; Diet; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mexican Americans; Middle Aged; Phosphatidylcholines; Sphingomyelins; White People | 2008 |
Dietary patterns, food groups, and nutrients as predictors of plasma choline and betaine in middle-aged and elderly men and women.
Topics: Aged; Betaine; Bread; Cardiovascular Diseases; Choline; Cohort Studies; Diet Surveys; Dietary Fats; Eggs; Factor Analysis, Statistical; Feeding Behavior; Female; Folic Acid; Food, Fortified; Humans; Linear Models; Male; Meat; Metabolic Syndrome; Middle Aged; Norway; Phospholipids | 2008 |
[Methyl-containing diet of mothers affects the AGOUTI gene expression in the offspring of rats with various behavioral types].
Topics: Aggression; Agouti Signaling Protein; Animals; Behavior, Animal; Betaine; Choline; Dietary Supplements; Female; Folic Acid; Hair Color; Methionine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Selection, Genetic; Species Specificity; Vitamin B 12; Zinc | 2009 |
A clinical puzzle: fibrates and homocysteine elevation: editorial to: "fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine" by M. Lever et al.
Topics: Animals; Betaine; Bezafibrate; Clofibric Acid; Dyslipidemias; Folic Acid; Homocysteine; Humans; Hypolipidemic Agents; Metabolic Syndrome | 2009 |
Choline and betaine intake and risk of breast cancer among post-menopausal women.
Topics: Adult; Aged; Aged, 80 and over; Betaine; Breast Neoplasms; Choline; Female; Folic Acid; Humans; Middle Aged; Postmenopause; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Risk | 2010 |
CpG methylation of a silent controlling element in the murine Avy allele is incomplete and unresponsive to methyl donor supplementation.
Topics: Agouti Signaling Protein; Alleles; Animals; Base Sequence; Betaine; Choline; CpG Islands; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Genes, Intracisternal A-Particle; Germ Cells; Male; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Insertional; Phenotype; Promoter Regions, Genetic; Retroelements | 2010 |
Are dietary choline and betaine intakes determinants of total homocysteine concentration?
Topics: Betaine; Cardiovascular Diseases; Choline; Cognition Disorders; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Vitamin B 12; Vitamin B 6 | 2010 |
Subtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet.
Topics: Abnormalities, Drug-Induced; Animals; Betaine; Choline; Diet; DNA Methylation; Drug Resistance; Ethanol; Female; Fetal Death; Fetal Development; Folic Acid; Gene Expression; Genomic Imprinting; Insulin-Like Growth Factor II; Male; Maternal-Fetal Exchange; Methanol; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Species Specificity; Vitamin B 12 | 2011 |
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carbon; Choline; Diet; Fatty Liver; Female; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; RNA, Messenger; Sex Factors | 2010 |
High intake of folate from food sources is associated with reduced risk of esophageal cancer in an Australian population.
Topics: Adenocarcinoma; Adult; Aged; Alcohol Drinking; Australia; Barrett Esophagus; Betaine; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Dietary Supplements; Esophageal Neoplasms; Esophagus; Female; Folic Acid; Humans; Logistic Models; Male; Methionine; Middle Aged; Risk Factors; Smoking; Vitamin B Complex | 2011 |
Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes.
Topics: Animals; Bacteria; Betaine; Choline; Colitis; Dietary Supplements; Disease Susceptibility; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Humans; Intestinal Mucosa; Male; Maternal Nutritional Physiological Phenomena; Metagenome; Mice; Mice, Inbred C57BL; Pedigree; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12 | 2011 |
Dietary supplementation with methyl donor groups could prevent nonalcoholic fatty liver.
Topics: Animals; Betaine; Choline; Dietary Fats; Dietary Sucrose; Dietary Supplements; Disease Models, Animal; Fatty Liver; Folic Acid; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Vitamin B 12 | 2011 |
Triplex tetra-primer ARMS-PCR method for the simultaneous detection of MTHFR c.677C>T and c.1298A>C, and MTRR c.66A>G polymorphisms of the folate-homocysteine metabolic pathway.
Topics: Betaine; DNA Primers; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Homocysteine; Humans; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide | 2012 |
Methylation capacity in children with severe cerebral palsy.
Topics: Betaine; Biomarkers; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Choline; Cystathionine; DNA Methylation; Erythrocyte Indices; Erythrocyte Membrane; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Queensland; Severity of Illness Index; Uric Acid | 2012 |
Gestational intake of methyl donors and global LINE-1 DNA methylation in maternal and cord blood: prospective results from a folate-replete population.
Topics: Adult; Betaine; Choline; Diet; Dietary Supplements; DNA Methylation; Female; Fetal Blood; Folic Acid; Humans; Infant, Newborn; Long Interspersed Nucleotide Elements; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Vitamin B 12 | 2012 |
Maternal intake of methyl-donor nutrients and child cognition at 3 years of age.
Topics: Adult; Betaine; Child Development; Child, Preschool; Choline; Cognition; Cohort Studies; Diet; DNA Methylation; Female; Folic Acid; Food; Humans; Massachusetts; Maternal Age; Maternal Nutritional Physiological Phenomena; Methionine; Multivariate Analysis; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prenatal Exposure Delayed Effects; Prospective Studies; Surveys and Questionnaires; Vitamin B 12 | 2012 |
Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline Deficiency; Dietary Supplements; Enzyme Inhibitors; Folic Acid; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Wistar; Sarcosine | 2012 |
Plasma choline and betaine correlate with serum folate, plasma S-adenosyl-methionine and S-adenosyl-homocysteine in healthy volunteers.
Topics: Adolescent; Adult; Betaine; Choline; Chromatography, High Pressure Liquid; DNA Methylation; Female; Folic Acid; Gonadal Steroid Hormones; Humans; Linear Models; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Sex Factors; Tandem Mass Spectrometry; Young Adult | 2013 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
Choline and betaine intake is inversely associated with breast cancer risk: a two-stage case-control study in China.
Topics: Betaine; Breast Neoplasms; Case-Control Studies; China; Choline; Diet; Eating; Female; Folic Acid; Humans; Logistic Models; Middle Aged; Odds Ratio; Risk Factors; Surveys and Questionnaires | 2013 |
Acute myocardial infarction in a young patient with hyperhomocysteinaemia.
Topics: Acute Disease; Adult; Betaine; Coronary Vessels; Folic Acid; Heart; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Myocardium; Thrombosis; Troponin; Ventricular Function, Left | 2012 |
Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.
Topics: Animals; Betaine; Choline; Craniofacial Abnormalities; Dietary Supplements; Disease Models, Animal; Face; Female; Folic Acid; Gastrulation; Jaw; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Parity; Pregnancy; Proteins; Risk Factors; Vitamin B 12; Vitamin B Complex | 2013 |
Investigating multiple candidate genes and nutrients in the folate metabolism pathway to detect genetic and nutritional risk factors for lung cancer.
Topics: Aged; Alcohol Drinking; Bayes Theorem; Betaine; Case-Control Studies; Choline; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Vitamin B Complex | 2013 |
Choline intake during pregnancy and child cognition at age 7 years.
Topics: Adult; Betaine; Child; Child Development; Choline; Cognition; Dietary Supplements; Female; Folic Acid; Humans; Intelligence; Male; Massachusetts; Memory; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prenatal Exposure Delayed Effects; Smoking; Socioeconomic Factors; Vitamin B 12 | 2013 |
Diet influences expression of autoimmune-associated genes and disease severity by epigenetic mechanisms in a transgenic mouse model of lupus.
Topics: Animals; Antibodies, Antinuclear; Betaine; CD40 Ligand; Choline; Coenzymes; Diet; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Silencing; Genetic Predisposition to Disease; Lupus Erythematosus, Systemic; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Micronutrients; Riboflavin; Vitamin B 12; Vitamin B 6; Zinc | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.
Topics: Adult; Betaine; Choline; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Nutritional Status; Pregnancy; Sarcosine; Spain; Vitamin B 12 | 2013 |
Cobalamin C defect presenting with isolated pulmonary hypertension.
Topics: Betaine; Brain; Child, Preschool; Diagnosis, Differential; Drug Therapy, Combination; Folic Acid; Genetic Carrier Screening; Humans; Hydroxocobalamin; Hypertension, Pulmonary; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Infant; Infant, Newborn; Injections, Intramuscular; Lung; Magnetic Resonance Imaging; Male; Metabolism, Inborn Errors; Neonatal Screening; Proto-Oncogene Proteins c-cbl; Pulmonary Artery; Tomography, X-Ray Computed; Vitamin B 12 Deficiency | 2013 |
Low plasma vitamin B-12 is associated with a lower pregnancy-associated rise in plasma free choline in Canadian pregnant women and lower postnatal growth rates in their male infants.
Topics: Adult; Betaine; British Columbia; Child Development; Choline; Dietary Supplements; Female; Folic Acid; Humans; Infant; Male; Methionine; Middle Aged; Pregnancy; Prospective Studies; Sarcosine; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Polydopamine-based simple and versatile surface modification of polymeric nano drug carriers.
Topics: Betaine; Biological Transport; Drug Carriers; Folic Acid; Humans; Indoles; KB Cells; Lactic Acid; Nanoparticles; Oligopeptides; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polymethacrylic Acids; Safety; Surface Properties | 2014 |
Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease.
Topics: Adult; Aged; Betaine; Case-Control Studies; Choline; Cohort Studies; Diet; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B Complex | 2014 |
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads.
Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult | 2014 |
Severe 5,10-methylenetetrahydrofolate reductase deficiency and two MTHFR variants in an adolescent with progressive myoclonic epilepsy.
Topics: Adolescent; Betaine; Female; Folic Acid; Homocystinuria; Humans; Lipotropic Agents; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Mutation; Myoclonic Epilepsies, Progressive; Psychotic Disorders; Vitamin B Complex | 2014 |
Supplementation with methyl donors during lactation to high-fat-sucrose-fed dams protects offspring against liver fat accumulation when consuming an obesogenic diet.
Topics: Adipose Tissue; Animals; Betaine; Body Composition; Choline; Diet; Diet, High-Fat; Dietary Sucrose; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Female; Folic Acid; Gene Expression; Lactation; Liver; Male; Maternal Nutritional Physiological Phenomena; Obesity; Pregnancy; Rats; Rats, Wistar; Receptors, Leptin; RNA, Messenger; Vitamin B 12 | 2014 |
Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects.
Topics: Adult; Betaine; Case-Control Studies; Choline; Dietary Supplements; Female; Folic Acid; Genome, Human; Genotype; Humans; Logistic Models; Neural Tube Defects; Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Selection, Genetic; Young Adult | 2014 |
Maternal methyl-enriched diet in rat reduced the audiogenic seizure proneness in progeny.
Topics: Animals; Animals, Newborn; Betaine; Choline; Diet; Epilepsy, Reflex; Female; Folic Acid; Male; Maternal Welfare; Methionine; Methylation; Pregnancy; Rats; Rats, Wistar; Vitamin B 12 | 2014 |
Reproducibility and validity of an FFQ to assess usual intake of methyl-group donors.
Topics: Adolescent; Adult; Belgium; Betaine; Choline; Diet; Diet Surveys; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Nutrition Assessment; Reproducibility of Results; Surveys and Questionnaires; Young Adult | 2015 |
Clinical pattern, mutations and in vitro residual activity in 33 patients with severe 5, 10 methylenetetrahydrofolate reductase (MTHFR) deficiency.
Topics: Ataxia; Betaine; Child; Female; Folic Acid; Genetic Association Studies; Homocystinuria; Humans; Intellectual Disability; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Mutation; Phenotype; Psychotic Disorders; Retrospective Studies; Spinal Cord Diseases; Vitamin B 12 | 2016 |
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6 | 2015 |
A method comparison of a food frequency questionnaire to measure folate, choline, betaine, vitamin C and carotenoids with 24-h dietary recalls in women of reproductive age.
Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; Betaine; Body Mass Index; Carotenoids; Choline; Diet Surveys; Educational Status; Energy Intake; Ethnicity; Female; Folic Acid; Follow-Up Studies; Humans; Mental Recall; Micronutrients; Nutrition Assessment; Reproducibility of Results; Reproduction; Surveys and Questionnaires; United Kingdom; White People; Young Adult | 2016 |
Betaine is as effective as folate at re-synthesizing methionine for protein synthesis during moderate methionine deficiency in piglets.
Topics: Animals; Betaine; Carbon Isotopes; Choline; Cysteine; Diet; Dietary Supplements; Folic Acid; Homocysteine; Methionine; Models, Biological; Oxidation-Reduction; Phenylalanine; Protein Biosynthesis; Swine | 2016 |
Serum betaine but not choline is inversely associated with breast cancer risk: a case-control study in China.
Topics: Adult; Aged; Betaine; Breast Neoplasms; Case-Control Studies; China; Choline; Diet; Exercise; Female; Folic Acid; Humans; Logistic Models; Middle Aged; Nutritional Status; Risk Factors; Socioeconomic Factors | 2017 |
Components of One-carbon Metabolism Other than Folate and Colorectal Cancer Risk.
Topics: Aged; Amino Acids; Betaine; Biomarkers; Biomarkers, Tumor; Case-Control Studies; Choline; Colorectal Neoplasms; Female; Folic Acid; Follow-Up Studies; Humans; Logistic Models; Male; Methionine; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Prospective Studies; Protective Factors; Sarcosine; Sweden | 2016 |
Maternal Methyl-Group Donor Intake and Global DNA (Hydroxy)Methylation before and during Pregnancy.
Topics: 5-Methylcytosine; Adult; Belgium; Betaine; Biomarkers; Choline; Cohort Studies; Cytosine; Diet; Dietary Supplements; DNA Methylation; Feeding Behavior; Female; Folic Acid; Humans; Hydroxylation; Leukocytes; Longitudinal Studies; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Prospective Studies; Self Report | 2016 |
Dietary methyl donors affect in vivo methionine partitioning between transmethylation and protein synthesis in the neonatal piglet.
Topics: Animals; Betaine; Choline; Cysteine; Diet; Feeding Behavior; Folic Acid; Methionine; Methylation; Protein Biosynthesis; Swine | 2016 |
Dietary Methyl Donors Contribute to Whole-Body Protein Turnover and Protein Synthesis in Skeletal Muscle and the Jejunum in Neonatal Piglets.
Topics: Animals; Animals, Newborn; Betaine; Choline; Diet; Dose-Response Relationship, Drug; Female; Folic Acid; Jejunum; Male; Methionine; Muscle, Skeletal; Phenylalanine; Protein Biosynthesis; Swine | 2016 |
Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study.
Topics: Adipose Tissue; Adolescent; Adult; Betaine; Birth Weight; Body Composition; Body Mass Index; Choline; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Infant; Linear Models; Male; Methionine; Middle Aged; Nutritional Status; Prospective Studies; Sensitivity and Specificity; Singapore; Vitamin B 12; Young Adult | 2016 |
Dietary and supplemental maternal methyl-group donor intake and cord blood DNA methylation.
Topics: Adult; Betaine; Choline; Cohort Studies; Diet; Dietary Supplements; DNA Methylation; Epigenomics; Feeding Behavior; Female; Fetal Blood; Folic Acid; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Nutrition Surveys; Pregnancy; Surveys and Questionnaires | 2017 |
Prenatal alcohol-induced neuroapoptosis in rat brain cerebral cortex: protective effect of folic acid and betaine.
Topics: Animals; Animals, Newborn; Apoptosis; Betaine; Blood Alcohol Content; Calpain; Caspase 3; Cathepsin B; Cathepsin L; Central Nervous System Depressants; Cerebral Cortex; Cytochromes c; Disease Models, Animal; Ethanol; Female; Folic Acid; Neuroprotective Agents; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2017 |
Maternal intake of methyl-group donors affects DNA methylation of metabolic genes in infants.
Topics: Betaine; Choline; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Folic Acid; High-Throughput Nucleotide Sequencing; Humans; Infant; Insulin-Like Growth Factor II; Leptin; Maternal Nutritional Physiological Phenomena; Nutrition Surveys; Pregnancy; Retinoid X Receptor alpha; Sequence Analysis, DNA | 2017 |
The effect of paternal methyl-group donor intake on offspring DNA methylation and birth weight.
Topics: Adult; Belgium; Betaine; Birth Weight; Choline; DNA Methylation; Female; Fetal Blood; Folic Acid; Humans; Male; Methionine; Middle Aged; Obesity | 2017 |
Combined methylmalonic acidemia and homocysteinemia presenting predominantly with late-onset diffuse lung disease: a case series of four patients.
Topics: Betaine; Child; Child, Preschool; Female; Folic Acid; Homocystinuria; Humans; Infant; Lung Diseases; Male; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2017 |
[Effect of peripheral bloodgenomic DNA methylation on the relationship between methyl donor status and risk of breast cancer].
Topics: Betaine; Breast Neoplasms; Case-Control Studies; Choline; Colonic Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Humans; Methionine; Nutrition Surveys; Risk | 2017 |
One-carbon metabolite ratios as functional B-vitamin markers and in relation to colorectal cancer risk.
Topics: Betaine; Biomarkers, Tumor; Carbon; Case-Control Studies; Colorectal Neoplasms; Creatinine; Cysteine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Riboflavin; Vitamin B 12; Vitamin B Complex | 2019 |
Fetal one-carbon nutrient concentrations may be affected by gestational diabetes.
Topics: Adult; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Fetal Blood; Fetal Development; Fetus; Folic Acid; Humans; Infant, Newborn; Nutrients; Nutritional Status; Pregnancy; Prenatal Care; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2018 |
Betaine or folate can equally furnish remethylation to methionine and increase transmethylation in methionine-restricted neonates.
Topics: Animals; Animals, Newborn; Betaine; Blood; Choline; Female; Folic Acid; Male; Methionine; Methylation; Swine; Vitamin U | 2018 |
PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women.
Topics: Adolescent; Adult; Alleles; Betaine; Birth Weight; Carnitine; Choline; Choline-Phosphate Cytidylyltransferase; Diet; Female; Folic Acid; Genotype; Homozygote; Humans; Infant, Newborn; Methylamines; Nutritional Status; Phosphatidylethanolamine N-Methyltransferase; Poland; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Young Adult | 2018 |
Effect of maternal or post-weaning methyl donor supplementation on growth performance, carcass traits, and meat quality of pig offspring.
Topics: Animal Feed; Animals; Betaine; Body Weight; Dietary Supplements; Female; Folic Acid; Humans; Male; Maternal Nutritional Physiological Phenomena; Meat; Methionine; Pregnancy; Swine; Weaning | 2019 |
Sex differences in hepatic one-carbon metabolism.
Topics: Betaine; Carbon; Choline; Female; Folic Acid; Homocysteine; Humans; Liver; Male; Models, Biological; Sex Characteristics | 2018 |
Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease.
Topics: Animals; Betaine; Carbon; Choline; Diet, High-Fat; Dietary Supplements; DNA Methylation; Folic Acid; Glutathione; Homocysteine; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; S-Adenosylmethionine | 2019 |
Dietary Intake of Nutrients Involved in One-Carbon Metabolism and Risk of Gastric Cancer: A Prospective Study.
Topics: Adult; Aged; Australia; Betaine; Carbon; Case-Control Studies; Choline; Diet; Female; Folic Acid; Helicobacter Infections; Humans; Male; Middle Aged; Nutrients; Odds Ratio; Riboflavin; Risk Factors; Stomach Neoplasms; Vitamin B Complex | 2019 |
One-Carbon Cofactor Intake and Risk of Neural Tube Defects Among Women Who Meet Folic Acid Recommendations: A Multicenter Case-Control Study.
Topics: Adult; Betaine; Carbon; Case-Control Studies; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Methionine; Neural Tube Defects; Odds Ratio; Pregnancy; Risk Factors; Socioeconomic Factors; United States; Vitamin B 12; Vitamin B 6 | 2019 |
A high methyl donor diet affects physiology and behavior in Peromyscus polionotus.
Topics: Absorptiometry, Photon; Animals; Anxiety; Behavior, Animal; Betaine; Choline; Diet; DNA Methylation; Female; Folic Acid; Gonadotropin-Releasing Hormone; Male; Peromyscus; Social Behavior; Vitamin B 12 | 2019 |
MtpB, a member of the MttB superfamily from the human intestinal acetogen
Topics: Betaine; Demethylation; Energy Metabolism; Eubacterium; Folic Acid; Humans; Intestines; Methylamines; Methylation; Methyltransferases; Microbiota; Proline; Tetrahydrofolates | 2019 |
A diet rich in taurine, cysteine, folate, B
Topics: Alzheimer Disease; Animals; Betaine; Brain; Cysteine; Diet; Dietary Supplements; Folic Acid; Gases; Humans; Hydrogen Sulfide; Methylation; Risk; Taurine; Vitamin B 12 | 2019 |
Using Differential Threshold Effects of Individual and Combined Periconceptional Methyl Donor Status on Maternal Genomic LINE-1 and Imprinted H19 DNA Methylation to Predict Birth Weight Variance in the Taiwan Pregnancy-Newborn Epigenetics (TPNE) Cohort St
Topics: Adult; Betaine; Birth Weight; Choline; Cohort Studies; Differential Threshold; DNA; DNA Methylation; Epigenomics; Female; Folic Acid; Genomics; Humans; Infant, Newborn; Long Interspersed Nucleotide Elements; Pregnancy; RNA, Long Noncoding; Taiwan | 2020 |
Effects of rumen-protected folic acid and betaine supplementation on growth performance, nutrient digestion, rumen fermentation and blood metabolites in Angus bulls.
Topics: Animal Feed; Animals; Betaine; Cattle; Dietary Supplements; Digestion; Fatty Acids, Volatile; Fermentation; Folic Acid; Gastrointestinal Microbiome; Male; Rumen | 2020 |
Adult-onset methylenetetrahydrofolate reductase deficiency.
Topics: Age of Onset; Betaine; Dysarthria; Folic Acid; Gait Ataxia; Homocystinuria; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Psychotic Disorders; Tremor; Vitamin B 12; Young Adult | 2020 |
Low protein diet and methyl-donor supplements modify testicular physiology in mice.
Topics: Animals; Betaine; Choline; Diet, Protein-Restricted; Dietary Supplements; Fatty Acids; Folic Acid; Male; Methionine; Mice; Testis; Vitamin B 12 | 2020 |
Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis.
Topics: Adenosylhomocysteinase; Animals; Betaine; Cystathionine beta-Synthase; Disease Models, Animal; Folic Acid; Gene Expression Regulation, Enzymologic; Glycine Hydroxymethyltransferase; Homocysteine; Homocystinuria; Humans; Liver; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Polyamines | 2021 |
POSITIVE EFFECT OF BETAINE-ARGININE SUPPLEMENT ON IMPROVED HYPERHOMOCYSTEINEMIA TREATMENT IN MARRIED COUPLES WITH REPRODUCTIVE DISORDERS.
Topics: Arginine; Betaine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12 | 2020 |
Dietary Methyl-Group Donor Intake and Breast Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Topics: Adult; Aged; Betaine; Breast Neoplasms; Choline; Diet; Europe; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Prospective Studies; Risk Factors | 2021 |
Validation of a food-frequency questionnaire to assess methyl-group donor intake in preschoolers.
Topics: Adult; Betaine; Child; Choline; Diet; Diet Records; Diet Surveys; Energy Intake; Folic Acid; Humans; Reproducibility of Results; Surveys and Questionnaires | 2022 |
Optimal Dietary Intake Composition of Choline and Betaine Is Associated with Minimized Visceral Obesity-Related Hepatic Steatosis in a Case-Control Study.
Topics: Adiposity; Aged; Betaine; Biomarkers; Body Composition; Case-Control Studies; Choline; Diet Records; Eating; Fatty Liver; Female; Folic Acid; Humans; Male; Middle Aged; Obesity; Obesity, Abdominal; Odds Ratio; Taiwan; Ultrasonography | 2022 |
Micronutrients of the one-carbon metabolism cycle are altered in mothers and neonates by gestational diabetes and are associated with weight, height and head circumference at birth.
Topics: Betaine; Birth Weight; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Glycine; Humans; Infant, Newborn; Micronutrients; Mothers; Pregnancy; Tandem Mass Spectrometry; Vitamin B 12 | 2022 |
Lower plasma glutathione, choline, and betaine concentrations are associated with fatty liver in postmenopausal women.
Topics: Betaine; Biomarkers; Choline; Fatty Liver; Female; Folic Acid; Glutathione; Homocysteine; Humans; Postmenopause | 2022 |
Effect of Beer Consumption on Methylation and Redox Metabolism.
Topics: Antioxidants; Apolipoproteins; Beer; Betaine; Cholesterol, LDL; Folic Acid; Homocysteine; Humans; Male; Methylation; Oxidation-Reduction; Superoxide Dismutase; Uric Acid; Vitamin B 6 | 2022 |
One-carbon metabolism and related pathways in ruminal and small intestinal epithelium of lactating dairy cows.
Topics: Amino Acids; Animals; Antioxidants; Betaine; Carbon; Cattle; Creatine; Diet; Duodenum; Female; Folic Acid; Glutathione; Intestinal Mucosa; Lactation; Methionine; Milk; Rumen | 2023 |
Serum 5-Methyltetrahydrofolate Status Is Associated with One-Carbon Metabolism-Related Metabolite Concentrations and Enzyme Activity Indicators in Young Women.
Topics: Adolescent; Adult; Betaine; Carbon; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Pregnancy; S-Adenosylmethionine; Young Adult | 2023 |
Association between nutrient intake related to the one-carbon metabolism and colorectal cancer risk: a case-control study in the Basque Country.
Topics: Betaine; Carbon; Case-Control Studies; Choline; Colorectal Neoplasms; Diet; Eating; Folic Acid; Humans; Logistic Models; Risk Factors; Spain | 2023 |
Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy.
Topics: Alzheimer Disease; Animals; Betaine; Carbon; Choline; Dietary Supplements; Disease Models, Animal; Folic Acid; Humans; Mice; Mice, Transgenic; Phosphorylation; Protein Phosphatase 2; tau Proteins; Tauopathies | 2023 |
Periconceptional intakes of methyl donors and other micronutrients involved in one-carbon metabolism may further reduce the risk of neural tube defects in offspring: a United States population-based case-control study of women meeting the folic acid recom
Topics: Betaine; Carbon; Case-Control Studies; Choline; Female; Folic Acid; Humans; Methionine; Micronutrients; Neural Tube Defects; Racemethionine; Trace Elements; Vitamin B 6 | 2023 |