betaine and dasatinib

betaine has been researched along with dasatinib in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	4 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dalziel, G; Dean, B; Pang, J; Salphati, L; Ware, JA	1
Benet, LZ; Budha, N; Dean, B; Ding, X; Dresser, MJ; Frassetto, LA; Frymoyer, A; Jin, JY; Salphati, L; Smelick, GS; Ware, JA; Yago, MR	1

Reviews

1 review(s) available for betaine and dasatinib

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for betaine and dasatinib

Article	Year
The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria. The AAPS journal, 2014, Volume: 16, Issue:6 Topics: Absorption, Physiological; Achlorhydria; Adult; Antineoplastic Agents; Area Under Curve; Betaine; Cross-Over Studies; Dasatinib; Drug Interactions; Female; Gastric Acid; Healthy Volunteers; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Proton Pump Inhibitors; Pyrimidines; Rabeprazole; Thiazoles; Young Adult	2014

Article

Year

The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria.

The AAPS journal, 2014, Volume: 16, Issue:6

Topics: Absorption, Physiological; Achlorhydria; Adult; Antineoplastic Agents; Area Under Curve; Betaine; Cross-Over Studies; Dasatinib; Drug Interactions; Female; Gastric Acid; Healthy Volunteers; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Proton Pump Inhibitors; Pyrimidines; Rabeprazole; Thiazoles; Young Adult

2014

Other Studies

2 other study(ies) available for betaine and dasatinib

Article	Year
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Pharmacokinetics and absorption of the anticancer agents dasatinib and GDC-0941 under various gastric conditions in dogs--reversing the effect of elevated gastric pH with betaine HCl. Molecular pharmaceutics, 2013, Nov-04, Volume: 10, Issue:11 Topics: Absorption; Achlorhydria; Animals; Antineoplastic Agents; Betaine; Dasatinib; Dogs; Famotidine; Gastric Mucosa; Hydrogen-Ion Concentration; Indazoles; Male; Pentagastrin; Proton Pump Inhibitors; Pyrimidines; Stomach; Sulfonamides; Thiazoles	2013

Article

Year

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012

Pharmacokinetics and absorption of the anticancer agents dasatinib and GDC-0941 under various gastric conditions in dogs--reversing the effect of elevated gastric pH with betaine HCl.

Molecular pharmaceutics, 2013, Nov-04, Volume: 10, Issue:11

Topics: Absorption; Achlorhydria; Animals; Antineoplastic Agents; Betaine; Dasatinib; Dogs; Famotidine; Gastric Mucosa; Hydrogen-Ion Concentration; Indazoles; Male; Pentagastrin; Proton Pump Inhibitors; Pyrimidines; Stomach; Sulfonamides; Thiazoles

2013